CN106093370A - A kind of white mice experimental monitoring device - Google Patents

A kind of white mice experimental monitoring device Download PDF

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Publication number
CN106093370A
CN106093370A CN201610672160.XA CN201610672160A CN106093370A CN 106093370 A CN106093370 A CN 106093370A CN 201610672160 A CN201610672160 A CN 201610672160A CN 106093370 A CN106093370 A CN 106093370A
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white mice
groove
cover body
monitoring device
circular pedestal
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CN201610672160.XA
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CN106093370B (en
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卢丽花
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Kanglong Huacheng (Beijing) Biotechnology Co., Ltd.
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卢丽花
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082Supracellular entities, e.g. tissue, organisms
    • G01N33/5088Supracellular entities, e.g. tissue, organisms of vertebrates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01GWEIGHING
    • G01G19/00Weighing apparatus or methods adapted for special purposes not provided for in the preceding groups
    • G01G19/44Weighing apparatus or methods adapted for special purposes not provided for in the preceding groups for weighing persons
    • G01G19/50Weighing apparatus or methods adapted for special purposes not provided for in the preceding groups for weighing persons having additional measuring devices, e.g. for height
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15Medicinal preparations ; Physical properties thereof, e.g. dissolubility

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)

Abstract

The present invention relates to a kind of white mice experimental monitoring device, including a base and a transparent hemispherical cover body;Described base includes a circular pedestal and connects the connection seat of circular seat body sidewall, and described circular pedestal includes hollow chassis and the weighing pan being arranged in hollow chassis, is provided with weight sensor between described weighing pan and hollow chassis;The side of described transparent hemispherical cover body is hinged to be arranged on circular pedestal, is provided with a hook openings bottom the opposite side of described transparent hemispherical cover body;The junction of described circular pedestal and connection seat offers one first groove, and described connection seat offers the second groove, and described first groove and the second groove are connected;The afterbody of described second groove is provided with a white mice tail cramping body;It is provided with a limit assembly on the junction of described circular pedestal and connection seat.White mice can be placed in circular seat body by the present invention, carries out intravenous injection, and can detect the rhythm of the heart and the body temperature of the weight of white mice, in real time monitoring white mice.

Description

A kind of white mice experimental monitoring device
Technical field
The present invention relates to field of medical technology, particularly relate to a kind of white mice experimental monitoring device.
Background technology
Existing being required in field of medical technology carries out drug test to white mice, so that it is determined that the effect of medicine.Ratio The relatively often thing of operation, by after white mice is carried out intravenous drug observing white mice, in observation, needs in time The record heart beating of white mice and the change etc. of body temperature, and the most also white mice is weighed, record it big Little;The mode of conventional injection is all manually to pick up white mice, or is picked up by complicated equipment, then carries out intravenous injection, note Pick up again after penetrating to be placed in another container and observe, so move about and add workload.
Summary of the invention
It is an object of the invention to provide a kind of white mice experimental monitoring device, simple in construction, and injection convenient, can obtain The information such as the weight of white mice, the rhythm of the heart and body temperature;Can directly observe white mice situation after injection, white mice need not be moved to Another container is observed.
The present invention is achieved in that a kind of white mice experimental monitoring device, it is characterised in that: include a base and saturating Bright hemispherical cover body;Described base includes a circular pedestal and connects the connection seat of circular seat body sidewall, described circular pedestal bag Include hollow chassis and the weighing pan being arranged in hollow chassis, between described weighing pan and hollow chassis, be provided with weight sensing Device;Having a groove in the middle part of described weighing pan, be provided with an elastomeric pad in described groove, in described elastomeric pad, setting also has One for detecting the annular pressure sensor of the white mice rhythm of the heart;The middle part of described annular pressure sensor is provided with one for detecting The infrared temperature probe of white mice shell temperature;Described infrared temperature probe is connected with infrared measurement of temperature module through wire;In described Being provided with a rechargeable battery in empty chassis, described rechargeable battery is that a circuit board is powered, and described circuit board is provided with MCU, Described MCU is connected with weight sensor, annular pressure sensor and infrared measurement of temperature module;The one of described transparent hemispherical cover body Side is hinged to be arranged on circular pedestal, and the opposite side edge part of described transparent hemispherical cover body is provided with a hook openings, in order to After transparent hemispherical cover body covers, the tail of described white mice is stretched out by this hook openings;Described circular pedestal and connection seat Junction offers one first groove, described connection seat offers the second groove, described first groove and the second groove and is connected Connect;The afterbody of described second groove is provided with a white mice tail cramping body;It is provided with track, for described on described connection seat White mice tail cramping body moves forward and backward on that track;It is provided with one spacing on the junction of described circular pedestal and connection seat Assembly;Being equipped with four reset post on described transparent hemispherical cover body, described reset post is positioned at transparent hemispherical cover body End arranges a spacing net, and during in order to press under described reset post, white mice lived by this spacing guard, limits the action of white mice;Institute State the end that reset post is positioned at outside transparent hemispherical cover body and be provided with a gripper shoe;The arc top of described transparent hemispherical cover body is fixed Connecting and have a screw rod, described screw rod passes described gripper shoe center, and is arranged with a limited screw on this screw rod.
In an embodiment of the present invention, described elastomeric pad includes a pad and is arranged on the reset bullet under pad Spring;Back-moving spring compress after, described pad can be pressed into described in groove in.
In an embodiment of the present invention, the sidewall of described base is provided with a USB charging inlet, described USB charging The charged circuit of outfan of mouth is the charging of described rechargeable battery.
In an embodiment of the present invention, described connection seat be rubber connect seat, rubber connect seat can deviously with described circle Shape pedestal is connected.
In an embodiment of the present invention, described white mice tail cramping body includes a square framework, in described square framework Offering a screwed hole, on described screwed hole, spiral is provided with a manual screw, and described square framework is fixed in the second groove.
In an embodiment of the present invention, described limit assembly includes two support bars being arranged side by side, and two support bars It is located exactly at the top of the first groove;Set up between described support bar and have a spacing steel wire.
In an embodiment of the present invention, the inwall of described hook openings is provided with a resilient rubbber cushion.
In an embodiment of the present invention, described circular pedestal is provided with two drawing boxs, wherein first pull on the left side Box is used for placing aseptic cotton;Second drawing box on the right is used for placing ethanol for disinfection.
In an embodiment of the present invention, a micro electric pump it is provided with in described base;It is provided with one on described circuit board Micro electric pump drive circuit, described micro electric pump drive circuit is connected with described MCU;Described MCU is also associated with a switch, described Micro electric pump drive circuit is used for driving described micro electric pump;The water inlet end of described micro electric pump is communicated to described second pull In box;Described micro electric delivery side of pump is connected to a needle-based shower nozzle through a catheter;Described needle-based shower nozzle alignment second Groove, when being beneficial to have an injection, user passes through switch activated micro electric pump, and ethanol is sprayed onto the afterbody needle insertion site of white mice.
In an embodiment of the present invention, described catheter is stretched out by the sidewall of described circular pedestal, and is fixed on and is arranged at In clamp bracket on described track.
It is an advantage of the current invention that: the present invention by white mice is limited on a base, utilize base function of weighing, Heartbeat inspecting and infrared temperature detection, can realize while white mice carries out intravenous injection, obtaining more white mice life entity The information levied, and after white mice is carried out intravenous injection, decontrol cramping body, white mice can be with transparent hemispherical cover body Circular seat body in observe, improve the reliability of the conventional efficient to white mice and data.It is noted that this Invention protection is whole apparatus structure, for follow-up by pin injection operation, be not belonging to the present invention and protect category.
Accompanying drawing explanation
Fig. 1 is the structural representation of the embodiment of the present invention;
Fig. 2 is the top view of the embodiment of the present invention.
Detailed description of the invention
Below in conjunction with the accompanying drawings and embodiment the present invention will be further described.
As depicted in figs. 1 and 2, first embodiment of the invention one white mice experimental monitoring device, including a base 1 and Transparent hemispherical cover body 2;Described base 1 includes a circular pedestal 11 and connects the connection seat 12 of circular pedestal 11 sidewall, described Circular pedestal includes hollow chassis 111 and the weighing pan 112 being arranged in hollow chassis, at the bottom of described weighing pan 111 and hollow Weight sensor 113 it is provided with between dish;There is in the middle part of described weighing pan a groove 114, be provided with one in described groove elastic Pad 115, in described elastomeric pad, setting also has one for detecting the annular pressure sensor 116 of the white mice rhythm of the heart;Described ring The middle part of shape pressure transducer is provided with one for detecting the infrared temperature probe 117 of white mice shell temperature;Described infrared survey Temperature probe is connected with infrared measurement of temperature module through wire 118;Being provided with a rechargeable battery 119 in described hollow chassis, described fills Electricity battery is that a circuit board is powered, and described circuit board 120 is provided with MCU, described MCU and passes with weight sensor, annular pressure Sensor and infrared measurement of temperature module connect;The side of described transparent hemispherical cover body 2 is hinged to be arranged on circular pedestal 11, described A hook openings 21 it is provided with bottom the opposite side of transparent hemispherical cover body 2;Described circular pedestal 11 and the connection of connection seat 12 Place offers one first groove 3, and described connection seat 12 offers the second groove 4, described first groove 3 and the second groove 4 phase Connect;The afterbody of described second groove 4 is provided with a white mice tail cramping body 5;It is provided with track 18 on described connection seat 12, Move forward and backward on that track for described white mice tail cramping body.Owing to white mice is in different size, its tail length is also Different, therefore, adjusted the position of cramping body by this track, can guarantee that this device is suitable for different size of white mice;Institute State and be provided with a limit assembly 6 on the junction of circular pedestal 11 and connection seat 12;Wear on described transparent hemispherical cover body 2 Having four reset post 13, described reset post is positioned at the end of transparent hemispherical cover body and arranges a spacing net 14, in order to described multiple When pressing under the post of position, white mice lived by this spacing guard, limits the action of white mice;Described reset post is positioned at outside transparent hemispherical cover body End be provided with a gripper shoe 15;The arc top of described transparent hemispherical cover body is fixedly connected with a screw rod 16, and described screw rod is worn Cross described gripper shoe center, and on this screw rod, be arranged with a limited screw 17;So catch white mice and white mice is placed in circle In pedestal 11, the tail of white mice 8 is placed in the first groove 3 and the second groove 4 simultaneously, transparent hemispherical cover body 2 is covered Down and hook openings 21 is hooked on limit assembly 6, the tail of white mice is clamped by white mice tail cramping body 5 Live, carrying out injection operation with entry needle 7, if it is desired to keep white mice not tamper in transparent hemi cover body, can be by adjusting Joint limited screw 17, utilizes described spacing net to be fixed by white mice, it is worth mentioning at this point that, in the present embodiment, described reset post 13 is to be resetted by spring 27.
In one embodiment of the invention, described elastomeric pad includes a pad 1151 and is arranged on the reset under pad Spring 1152;Back-moving spring compress after, described pad can be pressed into described in groove 114 in.Arrange on the sidewall of described base Having a USB charging inlet 121, the charged circuit of outfan of described USB charging inlet is that described rechargeable battery 119 charges.
In the present invention, described connection seat 12 is that rubber connects seat, rubber connect seat can deviously with described circular pedestal 11 are connected.Described white mice tail cramping body 5 includes a square framework 51, and described square framework 51 offers a screwed hole (not shown), on described screwed hole, spiral is provided with a manual screw 52, and described square framework 51 is fixed in the second groove 4. White mice afterbody is fixed through square framework 51 carrying out tail by rotary screw 52.
Continuing with seeing Fig. 2, described limit assembly 6 includes two support bars being arranged side by side 61, and two support bars 61 It is located exactly at the top of the first groove 3;Set up between described support bar 61 and have a spacing steel wire 62.So hook openings 21 can hook On spacing steel wire 62, thus transparent hemispherical cover body 2 is fixed.Described transparent hemispherical cover body 2 is that transparent color is saturating Bright hemispherical cover body.So it is easy to the white mice situation after observing injection.
In an embodiment of the present invention, the inwall of described hook openings is provided with a resilient rubbber cushion 28, so transparent After hemispherical cover body 2 covers, can effectively protect the tail of white mice, it is to avoid white mice beats, cause tail epidermis impaired.
In an embodiment of the present invention, described circular pedestal is provided with two drawing boxs, wherein first pull on the left side Box 19 is used for placing aseptic cotton;Second drawing box 20 on the right is used for placing ethanol for disinfection.The two drawing box is provided with to be taken out Handle 25;This kind of structure can greatly facilitate the speed that white mice vein is had an injection, and having an injection due to white mice vein needs tail The skin in portion carries out disinfection cleaning, and therefore, this structure overcomes in the past when having an injection, and needs to be equipped with little of Cotton Gossypii, ethanol etc. and holds Device, not only takes up room, and carries trouble, for intravenous injection complex procedures.
In an embodiment of the present invention, an accumulator (not illustrating in figure), described accumulator it are provided with in described base Being that a micro electric pump 26 is powered through a switch (not illustrating in figure), the water inlet end of described micro electric pump is communicated to described second and takes out In pulling box 20;Described micro electric delivery side of pump is connected to a needle-based shower nozzle 23 through a catheter 22;Described needle-based shower nozzle Being directed at the second groove 4, when being beneficial to have an injection, user passes through switch activated micro electric pump, and ethanol is sprayed onto the afterbody pin of white mice Head insert division.
In an embodiment of the present invention, described catheter is stretched out by the sidewall of described circular pedestal, and is fixed on and is arranged at In clamp bracket 24 on described track 18.
Refering to shown in Fig. 2, in one embodiment of the invention, connecting seat 12 can be connected with described circular pedestal 11 deviously Connect.It may be said that this connection seat is flexible material, such as rubber etc..It is that user can protect by bending this connection seat having an injection The Tail skin of card white mice is tight, user can be allowed preferably to play pin, improve the success rate of acupuncture treatment.
In a word, the base of the present invention includes a circular pedestal and connects the connection seat of circular seat body sidewall, described transparent half The side of spherical cover body is hinged to be arranged on circular pedestal, and the junction of circular pedestal and connection seat offers one first groove, Offering the second groove on described connection seat, described first groove and the second groove are connected;The tail of white mice is placed in Carry out clamping tail by white mice tail cramping body on one groove and the second groove, white mice is carried out intravenous injection;Injection Rear relieving cramping body white mice can be observed in the circular seat body with transparent hemispherical cover body, simple to operate, and carries High work efficiency, if white mice is more active, can carry out spacing to white mice by spacing net, overcome existing needs Two people coordinate the drawback to white mice injection, greatly improve the intravenous efficiency of white mice and success rate.And After spacing for white mice, the belly of white mice is just attached on pad 1151, and pressure transducer just can accurately measure little Bai The heart beating of Mus, additionally, LOAD CELLS obtains the weight information of mouse, infrared body temperature monitoring is after monitoring white mice injection Shell temperature, improves the reliability of the conventional efficient to white mice and data.
The foregoing is only presently preferred embodiments of the present invention, all impartial changes done according to scope of the present invention patent with Modify, all should belong to the covering scope of the present invention.

Claims (10)

1. a white mice experimental monitoring device, it is characterised in that: include a base and a transparent hemispherical cover body;Described base Including a circular pedestal and the connection seat of connection circular seat body sidewall, during described circular pedestal includes hollow chassis and is arranged on Weighing pan on empty chassis, is provided with weight sensor between described weighing pan and hollow chassis;Have in the middle part of described weighing pan One groove, is provided with an elastomeric pad in described groove, in described elastomeric pad, setting also has one for detecting the white mice rhythm of the heart Annular pressure sensor;The middle part of described annular pressure sensor is provided with one for detecting the infrared of white mice shell temperature Temperature probe;Described infrared temperature probe is connected with infrared measurement of temperature module through wire;A charging it is provided with in described hollow chassis Battery, described rechargeable battery is that a circuit board is powered, described circuit board is provided with MCU, described MCU and weight sensor, Annular pressure sensor and infrared measurement of temperature module connect;The side of described transparent hemispherical cover body is hinged is arranged on circular pedestal On, the opposite side edge part of described transparent hemispherical cover body is provided with a hook openings, is beneficial to transparent hemispherical cover body and covers The tail of rear described white mice is stretched out by this hook openings;It is recessed that the junction of described circular pedestal and connection seat offers one first Groove, described connection seat offers the second groove, and described first groove and the second groove are connected;The afterbody of described second groove It is provided with a white mice tail cramping body;It is provided with track, for described white mice tail cramping body at this on described connection seat Move forward and backward on track;It is provided with a limit assembly on the junction of described circular pedestal and connection seat;Described transparent hemi Being equipped with four reset post on shape cover body, described reset post is positioned at the end of transparent hemispherical cover body and arranges a spacing net, uses During to press under described reset post, white mice lived by this spacing guard, limits the action of white mice;Described reset post is positioned at transparent hemi End outside shape cover body is provided with a gripper shoe;The arc top of described transparent hemispherical cover body is fixedly connected with a screw rod, described spiral shell Bar passes described gripper shoe center, and is arranged with a limited screw on this screw rod.
A kind of white mice experimental monitoring device the most according to claim 1, it is characterised in that: described elastomeric pad includes One pad and be arranged on the back-moving spring under pad;Back-moving spring compress after, described pad can be pressed into described in groove In.
A kind of white mice experimental monitoring device the most according to claim 1, it is characterised in that: set on the sidewall of described base Being equipped with a USB charging inlet, the charged circuit of outfan of described USB charging inlet is the charging of described rechargeable battery.
A kind of white mice experimental monitoring device the most according to claim 1, it is characterised in that: described connection seat is that rubber connects Joint chair, rubber connects seat and can be connected with described circular pedestal deviously.
A kind of white mice experimental monitoring device the most according to claim 1, it is characterised in that: described white mice tail clamps Body includes a square framework, and described square framework offers a screwed hole, and on described screwed hole, spiral is provided with a manual spiral shell Silk, described square framework is fixed in the second groove.
A kind of white mice experimental monitoring device the most according to claim 1, it is characterised in that: described limit assembly includes two The individual support bar being arranged side by side, and two support bars are located exactly at the top of the first groove;Set up between described support bar and have one Spacing steel wire.
A kind of white mice experimental monitoring device the most according to claim 1, it is characterised in that: the inwall of described hook openings It is provided with a resilient rubbber cushion.
A kind of white mice experimental monitoring device the most according to claim 1, it is characterised in that: arrange on described circular pedestal Having two drawing boxs, wherein first drawing box on the left side is used for placing aseptic cotton;Second drawing box on the right is used for placing sterilization Ethanol.
A kind of white mice experimental monitoring device the most according to claim 8, it is characterised in that: it is provided with in described base One micro electric pump;A micro electric pump drive circuit, described micro electric pump drive circuit and described MCU it is provided with on described circuit board Connect;Described MCU is also associated with a switch, and described micro electric pump drive circuit is used for driving described micro electric pump;Described is micro- The water inlet end of type electric pump is communicated in described second drawing box;Described micro electric delivery side of pump is connected to a pin through a catheter Hair style shower nozzle;Described needle-based shower nozzle is directed at the second groove, and when being beneficial to have an injection, user passes through switch activated micro electric pump, will Ethanol is sprayed onto the afterbody needle insertion site of white mice.
A kind of white mice experimental monitoring device the most according to claim 8, it is characterised in that: described catheter is by described The sidewall of circular pedestal stretches out, and is fixed in the clamp bracket being arranged on described track.
CN201610672160.XA 2016-08-16 2016-08-16 A kind of small white mouse experimental monitoring device Active CN106093370B (en)

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Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104013478A (en) * 2014-06-25 2014-09-03 李晓峰 Experimental rat fixing barrel
CN204318966U (en) * 2014-12-05 2015-05-13 黑占财 The special testing fixture of a kind of animal and veterinary
CN204364167U (en) * 2014-12-23 2015-06-03 辽宁中医药大学 A kind of rat fixing device
CN204446167U (en) * 2015-01-14 2015-07-08 苏州大学 Mouse tail vein injection experimental provision
CN204995608U (en) * 2015-10-02 2016-01-27 姜守丹 Inspecting device special for animal husbandry and veterinary
CN105287040A (en) * 2015-12-01 2016-02-03 上海市第一人民医院 Medical experiment animal treating and fixing equipment
CN205181526U (en) * 2015-12-01 2016-04-27 上海市第一人民医院 Fixing device is handled to medical experiment mouse
CN105662636A (en) * 2016-03-10 2016-06-15 苏州大学 Device for animal tail vein injection

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104013478A (en) * 2014-06-25 2014-09-03 李晓峰 Experimental rat fixing barrel
CN204318966U (en) * 2014-12-05 2015-05-13 黑占财 The special testing fixture of a kind of animal and veterinary
CN204364167U (en) * 2014-12-23 2015-06-03 辽宁中医药大学 A kind of rat fixing device
CN204446167U (en) * 2015-01-14 2015-07-08 苏州大学 Mouse tail vein injection experimental provision
CN204995608U (en) * 2015-10-02 2016-01-27 姜守丹 Inspecting device special for animal husbandry and veterinary
CN105287040A (en) * 2015-12-01 2016-02-03 上海市第一人民医院 Medical experiment animal treating and fixing equipment
CN205181526U (en) * 2015-12-01 2016-04-27 上海市第一人民医院 Fixing device is handled to medical experiment mouse
CN105662636A (en) * 2016-03-10 2016-06-15 苏州大学 Device for animal tail vein injection

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