CN202740008U - Automatic sampling and dosing system for animals - Google Patents
Automatic sampling and dosing system for animals Download PDFInfo
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- CN202740008U CN202740008U CN 201220276995 CN201220276995U CN202740008U CN 202740008 U CN202740008 U CN 202740008U CN 201220276995 CN201220276995 CN 201220276995 CN 201220276995 U CN201220276995 U CN 201220276995U CN 202740008 U CN202740008 U CN 202740008U
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- supplying system
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Abstract
The utility model provides an automatic sampling and dosing system for animals, and the system comprises a sampling system, a universal interface, a dosing system, a control system and a power system, wherein the sampling system and the dosing system are connected to the universal interface; the power system is used for driving the sampling system to actuate sampling action and driving the dosing system to actuate dosing action; and the control system is used for controlling a sampling process of the sampling system and a dosing process of the dosing system by controlling the power system. The automatic sampling and dosing system for the animals has automatic blood sampling and medicine injection functions, can sample or inject regularly and quantitatively according to experimental requirements and precisely record the experimental data, and can be widely applied to various experimental animals, such as mice, rats, cats, dogs, and pigs. The sampling success rate of the system is above 95 percent, and the system can re-sample automatically even if the sampling fails. The amount of sampled blood can reach 5ml at least, so that the harm to the experimental animals is minimized, and small animals can be chosen to replace big animals.
Description
Technical field
This utility model relates to animal experiment utensil, particularly, relates to a kind of animal drug-supplying system of automatically sampling.
Background technology
In the scientific research of the subjects such as medical science and the research, often need to test with animals such as rat, mice, rabbits, the test of animal is taken a blood sample to animal, and give animal medicine feed or injectable drug.Sampling apparatus of the prior art to be sampled into power low, and be difficult to accomplish trace blood, existing and can not finish sampling, can finish the device of administration again in same system in the prior art.
The utility model content
For defective of the prior art, the purpose of this utility model provides a kind of animal drug-supplying system of automatically sampling.
According to an aspect of the present utility model, a kind of animal drug-supplying system of automatically sampling is provided, comprise sampling system, universal interface, drug-supplying system, control system, dynamical system, wherein, described sampling system and drug-supplying system are connected to described universal interface, described dynamical system is used for driving described sampling system to be carried out sampling action and drives described drug-supplying system execution administration action, and described control system is used for controlling the sampling process of described sampling system and the administration process of described drug-supplying system by controlling described dynamical system.
Preferably, described sampling system comprises injection device and storage device, wherein, the sampling input of described injection device connects described universal interface, described storage device connects described injection device, is used for collecting the liquid that described injection device gathers, also as the part of described drug-supplying system, such as the part of injection device as drug-supplying system, then drug-supplying system is the automatic chemical feeding system to described injection device as the part of described sampling system the time.
Preferably, described injection device comprises syringe, the syringe positioning seat, locating groove, described syringe is fixed on the described syringe positioning seat by described locating groove, described dynamical system is finished push pull maneuver for the injection handle that drives described syringe, described dynamical system comprises motor, travelling gear, screw rod, slide, guide rod, leader fixed, wherein, described motor drives described screw rod rotation by travelling gear, one end of described screw rod connects described slide, described slide is installed on the described guide rod, can slide along described guide rod, described guide rod is installed between the described leader fixed and syringe positioning seat, and the slide draw-in groove of described slide is located the injection handle of described syringe.
Preferably, described universal interface comprises shell, outfan interface, equipment end interface and adapter sleeve, wherein, be connected by described adapter sleeve between the inner port of described outfan interface in described shell and the inner port of described equipment end interface in described shell.
Preferably, described outfan interface can freely rotate take its axis as rotating shaft.
Preferably, described universal interface also comprises following any or any two devices :-device folder, and wherein, described device folder is installed in the external port of described equipment end interface, and wherein, the external port of described equipment end interface is positioned at the outside of described shell;-vessel clamp, wherein, described vessel clamp is installed on described outfan interface.
Preferably, also comprise conduit, wherein, described conduit extends to the far distance port of described sheathed catheter by the proximal port of described sheathed catheter from the external port of described outfan interface, and the external port of the proximal port of described sheathed catheter and described outfan interface lays respectively at the both sides of described vessel clamp.
Preferably, also comprise autonomous drug-supplying system, wherein, described autonomous drug-supplying system comprises doser, described doser comprises support, and be installed in medicine box on the described support, rolling disc, fixed disk, motor, delivery tube, wherein, the medicine outlet of described medicine box is close to the upper surface of described rolling disc, the upper surface of described fixed disk is close to the lower surface of described rolling disc, described rolling disc is provided with the drug storage mouth, and described fixed disk is provided with drug delivery port, the upper end of described delivery tube be positioned at described drug delivery port under, described rolling disc is installed on the output shaft of described motor, and described control system connects described motor.
Preferably, described rolling disc can rotate between primary importance and the second position, when described rolling disc is positioned at described primary importance, described drug storage mouth be positioned at described medicine box medicine outlet under, when described rolling disc is positioned at the described second position, described drug storage mouth be positioned at described drug delivery port directly over.
Preferably, described autonomous drug-supplying system also comprises flip flop equipment, and wherein said flip flop equipment is positioned at the porch of described support, described flip flop equipment comprises shell, described shell is provided with the triggering window, is provided with sensing device on the described triggering window, and described sensing device connects described control system.
Compared with prior art, this utility model is by PC software records data, and control dynamical system driving syringe pump carries out drug administration by injection or extraction is sampled, and syringe pump is connected with universal interface with animal.When native system during in injection pattern, directly liquid in the syringe is injected in the animal body, when native system during in sampling configuration, the syringe extracting liquid is in syringe, and the storage device that reinjects is preserved.
Further, the function of automatic blood sampling of the present utility model and injectable drug can be sampled at regular time and quantity or injects and accurately record experimental data according to requirement of experiment, can be widely used in various laboratory animals such as mice, rat, cat, Canis familiaris L., pig etc.It is sampled into power more than 95%, unsuccessfully also can automatically again adopt even sample.The minimum amount of adopting that can reach 5 microlitres of blood sampling volume has also reduced to minimum to the injury of laboratory animal like this, and can select toy to replace large animal.In sampling process, instrument is quantitative sampling as requested, and blood unnecessary in the conduit can return in the animal body with normal saline automatically, in case the stop thing is fainted.Adopt low temperature storage device to prevent sample reaction, rotten, guarantee to test and finish smoothly.In whole sampling process, animal is unconstrained, can be movable freely in cage.Simultaneously, native system can adopt the automatic chemical feeding system, also can adopt autonomous drug-supplying system, if adopt the automatic chemical feeding system, then sampling and administration are integrated in the same injection device, if adopt autonomous drug-supplying system, then sampling apparatus works alone with autonomous drug-supplying system.In addition, this utility model has powerful software support, and all processes are all automatically finished sampling process by computer control and can be obtained and greatly saved manpower and time than the more accurate effectively numerical value of artificial sample.
Description of drawings
By reading the detailed description of non-limiting example being done with reference to the following drawings, it is more obvious that other features, objects and advantages of the present utility model will become:
Fig. 1 illustrates according to system block diagram of the present utility model;
Fig. 2 illustrates the structural representation according to injection device of the present utility model;
Fig. 3 illustrates the cross-sectional view according to universal interface of the present utility model;
Fig. 4 illustrates the contour structures schematic diagram according to universal interface of the present utility model;
Fig. 5 illustrates the structural representation according to autonomous drug-supplying system of the present utility model;
Fig. 6 illustrates the structural representation according to flip flop equipment in the autonomous drug-supplying system of the present utility model.
The specific embodiment
The animal that provides according to this utility model drug-supplying system of automatically sampling, comprise sampling system 2, universal interface 3, drug-supplying system, control system 1, dynamical system, wherein, described sampling system and drug-supplying system are connected to described universal interface, described dynamical system is used for driving described sampling system to be carried out sampling action and drives described drug-supplying system execution administration action, and described control system is used for controlling the sampling process of described sampling system and the administration process of described drug-supplying system by controlling described dynamical system.
Preferably, described sampling system comprises injection device and storage device 4, wherein, the sampling input of described injection device connects described universal interface, described storage device connects described injection device, is used for collecting the liquid that described injection device gathers, described injection device as the part of described sampling system the time also as the part of described drug-supplying system.
Wherein, described sampling system comprises injection device and dynamical system, wherein, described injection device comprises syringe 209, syringe positioning seat 2010, test rod 208, locating groove 207, the injection handle that described dynamical system is used for driving described syringe is finished push pull maneuver (when being used for finishing as sampling system blood drawing function or work as its injectable drug function as the automatic chemical feeding system), and described dynamical system comprises motor 201, travelling gear 202, screw rod 2011, slide 205, guide rod 204, leader fixed 203.
Particularly, described syringe is fixed on the described syringe positioning seat by described locating groove, and described test rod is for detection of the diameter of described syringe.Described motor drives described screw rod rotation by travelling gear, one end of described screw rod connects described slide, described slide is installed on the described guide rod, can slides along described guide rod, described guide rod is installed between the described leader fixed and syringe positioning seat, the injection handle of the described syringe in slide draw-in groove 206 location of described slide.
In a preference of the present embodiment, this utility model is by described dynamical system, so that the push pull maneuver of syringe can realize accurately push pull maneuver by motor under the control of control device, thereby guaranteed the accuracy of collection capacity and injection volume, be particularly suitable for trace and gather or administration.More specifically, described travelling gear is reduction gearing.Described motor is motor.Described control device connects described motor.
Described universal interface, comprise shell 303, outfan interface 308, equipment end interface 302, adapter sleeve 309, device folder 301, vessel clamp 304, sheathed catheter 306 and conduit, wherein, be connected by described adapter sleeve 309 between the inner port of described outfan interface 308 in described shell 303 and the inner port of described equipment end interface 302 in described shell 303.Described outfan interface 308, shell 303, equipment end interface 302 and adapter sleeve 309 coaxial settings.Described outfan interface 308 can freely rotate take its axis as rotating shaft.Described adapter sleeve 309 is made by polytetrafluoroethylmaterial material.
Be connected by the adapter sleeve 309 of being made by polytetrafluoroethylmaterial material between outfan interface 308 of the present utility model and the equipment end interface 302, but adapter sleeve 309 high temperature sterilizes, characteristics with antiacid alkali resistant, anti-various organic solvents, thereby guaranteed requirement of experiment, and this material friction coefficient is extremely low, also guaranteed this device freely rotate smooth and easy.
More specifically, described device folder 301 is installed in the external port of described equipment end interface 302, and wherein, the external port of described equipment end interface 302 is positioned at the outside of described shell.Described vessel clamp 304 is installed on described outfan interface 308.Described sheathed catheter 306 is installed on described vessel clamp 304, and described outfan interface 308 and described sheathed catheter 306 are separately fixed at the two ends of described vessel clamp 304, and is fixing with the first set bolt 307 and the second set bolt 305 respectively.
Further, the external port of the proximal port 3061 of described sheathed catheter 306 and described outfan interface 308 lays respectively at the both sides of described vessel clamp 304.Described conduit extends to the far distance port 3062 of described sheathed catheter 306 by the proximal port 3061 of described sheathed catheter 306 from the external port of described outfan interface 308.Described equipment end interface connects in described outer casing screw.
The present embodiment applies in the zoopery, this utility model in use, draw guiding tube by syringe and access described equipment end interface 302, described conduit is drawn by described outfan interface 308, penetrate the described sheathed catheter 306 from described sheathed catheter 306 upper ends, be connected on the animal body from the far distance port 3062 of described sheathed catheter 306.Animal can be freely movable, and sheathed catheter can freely rotate around the axle of universal interface.
Described autonomous drug-supplying system, comprise doser, described doser comprises support 502, and be installed in medicine box 501 on the described support 502, rolling disc 504, fixed disk 505, motor 506, delivery tube 507, wherein, the medicine outlet of described medicine box 501 is close to the upper surface of described rolling disc 504, the upper surface of described fixed disk 505 is close to the lower surface of described rolling disc 504, described rolling disc 504 is provided with drug storage mouth 509, described fixed disk 505 is provided with drug delivery port 508, the upper end of described delivery tube 507 be positioned at described drug delivery port 508 under, described rolling disc 504 is installed on the output shaft of described motor 506.
More specifically, described rolling disc 504 can rotate between primary importance and the second position, when described rolling disc 504 is positioned at described primary importance, described drug storage mouth 509 be positioned at described medicine box 501 medicine outlet under, when described rolling disc 504 is positioned at the described second position, described drug storage mouth 509 be positioned at described drug delivery port 508 directly over.
Further, described autonomous drug-supplying system also comprises flip flop equipment, and wherein said flip flop equipment is positioned at the porch of described support 502.Described flip flop equipment comprises shell 5010, and described shell 5010 is provided with and triggers window 5012, is provided with sensing device on the described triggering window 5012.Preferably, described sensing device comprises infrared emission tube 5011 and infrared receiver tube 5013.
In a preferred specific embodiment of the present utility model, first pill 503 is put into medicine box 501, when entering, animal limb triggers window 5012, interrupt the infrared ray of infrared emission tube 5011, make infrared receiver tube 5013 not receive signal, at this moment host computer sends a signal to motor 506, motor 506 drive rolling discs 504 revolve and turn around, pill 503 enters drug storage mouth 509 when 509 mouthfuls of drug storages rotate to medicine box 501 below, because drug storage mouth 509 is slightly larger than pill, only have a pill to enter the drug storage mouth fully, because of the resistance of other pill and medicine box 501 box walls, finally only have a pill to be brought into drug delivery port 8 by drug storage mouth 509, pill drops to the delivery tube 507 from drug delivery port 508, along delivery tube 507, pill is sent to the place that animal can be had.
Above specific embodiment of the utility model is described.It will be appreciated that, this utility model is not limited to above-mentioned specific implementations, and those skilled in the art can make various distortion or modification within the scope of the claims, and this does not affect flesh and blood of the present utility model.
Claims (10)
1. animal drug-supplying system of automatically sampling, it is characterized in that, comprise sampling system, universal interface, drug-supplying system, control system, dynamical system, wherein, described sampling system and drug-supplying system are connected to described universal interface, described dynamical system is used for driving described sampling system to be carried out sampling action and drives described drug-supplying system execution administration action, and described control system is used for controlling the automatic sampling process of described sampling system and the automatic chemical feeding process of described drug-supplying system by controlling described dynamical system.
2. the animal according to claim 1 drug-supplying system of automatically sampling, it is characterized in that, described sampling system comprises injection device and storage device, wherein, the sampling input of described injection device connects described universal interface, described storage device connects described injection device, is used for collecting the liquid that described injection device gathers, described injection device as the part of described sampling system the time also as the part of described drug-supplying system.
3. the animal according to claim 2 drug-supplying system of automatically sampling, it is characterized in that, described injection device comprises syringe, the syringe positioning seat, locating groove, described syringe is fixed on the described syringe positioning seat by described locating groove, described dynamical system is finished push pull maneuver for the injection handle that drives described syringe, described dynamical system comprises motor, travelling gear, screw rod, slide, guide rod, leader fixed, wherein, described motor drives described screw rod rotation by travelling gear, one end of described screw rod connects described slide, described slide is installed on the described guide rod, can slide along described guide rod, described guide rod is installed between the described leader fixed and syringe positioning seat, and the slide draw-in groove of described slide is located the injection handle of described syringe.
4. the animal according to claim 1 drug-supplying system of automatically sampling, it is characterized in that, described universal interface comprises shell, outfan interface, equipment end interface and adapter sleeve, wherein, be connected by described adapter sleeve between the inner port of described outfan interface in described shell and the inner port of described equipment end interface in described shell.
5. the animal according to claim 4 drug-supplying system of automatically sampling is characterized in that, described outfan interface can freely rotate take its axis as rotating shaft.
6. the animal according to claim 4 drug-supplying system of automatically sampling is characterized in that, described universal interface also comprises following any or any two devices:
-device folder, wherein, described device folder is installed in the external port of described equipment end interface, and wherein, the external port of described equipment end interface is positioned at the outside of described shell;
-vessel clamp, wherein, described vessel clamp is installed on described outfan interface.
7. the animal according to claim 6 drug-supplying system of automatically sampling, it is characterized in that, also comprise conduit, wherein, described conduit extends to the far distance port of described sheathed catheter by the proximal port of described sheathed catheter from the external port of described outfan interface, the external port of the proximal port of described sheathed catheter and described outfan interface lays respectively at the both sides of described vessel clamp.
8. the animal according to claim 1 drug-supplying system of automatically sampling, it is characterized in that, also comprise autonomous drug-supplying system, wherein, described autonomous drug-supplying system comprises doser, described doser comprises support, and be installed in medicine box on the described support, rolling disc, fixed disk, motor, delivery tube, wherein, the medicine outlet of described medicine box is close to the upper surface of described rolling disc, the upper surface of described fixed disk is close to the lower surface of described rolling disc, described rolling disc is provided with the drug storage mouth, described fixed disk is provided with drug delivery port, the upper end of described delivery tube be positioned at described drug delivery port under, described rolling disc is installed on the output shaft of described motor, described control system connects described motor.
9. the animal according to claim 8 drug-supplying system of automatically sampling, it is characterized in that, described rolling disc can rotate between primary importance and the second position, when described rolling disc is positioned at described primary importance, described drug storage mouth be positioned at described medicine box medicine outlet under, when described rolling disc is positioned at the described second position, described drug storage mouth be positioned at described drug delivery port directly over.
10. the animal according to claim 8 drug-supplying system of automatically sampling, it is characterized in that, described autonomous drug-supplying system also comprises flip flop equipment, wherein said flip flop equipment is positioned at the porch of described support, described flip flop equipment comprises shell, described shell is provided with the triggering window, is provided with sensing device on the described triggering window, and described sensing device connects described control system.
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CN 201220276995 CN202740008U (en) | 2012-06-12 | 2012-06-12 | Automatic sampling and dosing system for animals |
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CN 201220276995 CN202740008U (en) | 2012-06-12 | 2012-06-12 | Automatic sampling and dosing system for animals |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102697513A (en) * | 2012-06-12 | 2012-10-03 | 上海瑞曼信息科技有限公司 | Automatic sampling and dosing system for animals |
CN106236063A (en) * | 2016-08-16 | 2016-12-21 | 程翌 | A kind of white mice body weight, the rhythm of the heart, the operational approach of body-temperature monitoring device |
CN106264508A (en) * | 2016-08-16 | 2017-01-04 | 程翌 | A kind of white mice body weight, the rhythm of the heart, body-temperature monitoring device |
-
2012
- 2012-06-12 CN CN 201220276995 patent/CN202740008U/en not_active Expired - Fee Related
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102697513A (en) * | 2012-06-12 | 2012-10-03 | 上海瑞曼信息科技有限公司 | Automatic sampling and dosing system for animals |
CN106236063A (en) * | 2016-08-16 | 2016-12-21 | 程翌 | A kind of white mice body weight, the rhythm of the heart, the operational approach of body-temperature monitoring device |
CN106264508A (en) * | 2016-08-16 | 2017-01-04 | 程翌 | A kind of white mice body weight, the rhythm of the heart, body-temperature monitoring device |
CN106264508B (en) * | 2016-08-16 | 2024-03-15 | 浙江维通利华实验动物技术有限公司 | Body weight, heart rhythm and body temperature monitoring device for mice |
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GR01 | Patent grant | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130220 Termination date: 20190612 |
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CF01 | Termination of patent right due to non-payment of annual fee |