CN106237139A - The preparation method of the oral liquid for the treatment of acute infantile convulsion wind - Google Patents
The preparation method of the oral liquid for the treatment of acute infantile convulsion wind Download PDFInfo
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- CN106237139A CN106237139A CN201610718054.0A CN201610718054A CN106237139A CN 106237139 A CN106237139 A CN 106237139A CN 201610718054 A CN201610718054 A CN 201610718054A CN 106237139 A CN106237139 A CN 106237139A
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- rhizoma
- infantile convulsion
- oral liquid
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Abstract
The invention discloses the preparation method of a kind of oral liquid treating acute infantile convulsion wind, can effectively treat acute infantile convulsion wind, described oral liquid is obtained by the Chinese medicine composition alcohol steep of following weight portion: Concha Erosariae seu Cypraeae 57, Rhizoma Phragmitis 12-15, Plumula Nelumbinis 13-15, Herba Potentillae Chinensis 8 12, Rhizoma Coptidis 46, Rhizoma Bolbostematis 68, Radix Isatidis 8 12, Cornu Bubali 8 12, Herba Inulae 35, Fructus Trichosanthis 24, Thallus Laminariae (Thallus Eckloniae) 24, Sargassum 24, Concha Arcae 46, Rhizoma Gastrodiae 8 10, Ramulus Uncariae Cum Uncis 8 10, Arillus Longan 13-15, Radix Angelicae Sinensis 8 12, Caulis Spatholobi 8 12, Fructus Mori 8 12, the Rhizoma Atractylodis Macrocephalae 10 14, Semen Lablab Album 8 12, Rhizoma Dioscoreae 23-25, Radix Pseudostellariae 8 12, Rhizoma Acori Graminei 24, Cortex Albiziae 8 10 and Caulis Polygoni Multiflori 8 10.
Description
Technical field
The present invention relates to tcm field, particularly relate to the preparation method of a kind of oral liquid treating acute infantile convulsion wind.
Background technology
Acute infantile convulsion wind, disease name, also known as " infantile convulsion ", " convulsions ", popular name " convulsion ", is common a kind of anxious in children's period
Severe disease disease, has a convulsion with clinic, goes into a coma as cardinal symptom, and any season all can occur, typically with 1~the children's of 5 years old for many
Seeing, break with tremendous force, change rapidly, even can threaten children's's life.
Modern Western medicine to the treatment of acute infantile convulsion typically by injection or instillation medicine spasmolytic, such as close chloral, phenobarbital,
Diazepam (stabilizing), mannitol lobeline, nikethamide etc., but these methods are often cured the symptoms, not the disease, and can only temporarily alleviate
Or elimination symptom, it is impossible to radical cure, easily recur, and side effect is bigger.
Traditional Chinese Medicine thinks that infantile convulsion is that a kind of evil is waited.Such as " Dong-eui-bo-gam children's " cloud: " the danger person of children's's disease, without more
The card of infantile convulsion "." pediatrics releases mystery infantile convulsion ": " disease of children's, the heaviest only shy ".The cause of disease is with pathogenic wind-warm, damp and hot pestilential pathogen, interior
It is main for accumulate expectorant warm-served food amassing, it is possible to see being terrified suddenly.Fragile muscle and skin of children is weak, interspaces of skin and muscles being loose, and QI and blood is not filled, and easily experiences seasonal pathogen,
Going from the exterior into the interior, owl opens and high fever pathogen, thermoae fire-transformation, and raw expectorant contained by fire, the most then people seeks human blood, and cave in pericardium, priming liver-wind, occurs
Unconsciousness due to high fever, convulsion are fainted from fear, a speckle is told nosebleed, or seen vital QI cannot conquer pathogen, unconsciousness and collapse.In a word, the main pathogenesis of acute infantile convulsion be heat,
Expectorant, the influencing each other of frightened, wind, reciprocal causation.Its main sick position is at conscience two warp.At present, the Chinese patent medicine for the treatment of infantile convulsion has children's
Calculus Bovis dissipates, Xiaoer Huichun Dan, anti-pestilence and fever powder (red) etc..But, due to many-sided reason, existing tcm methods is to acute infantile convulsion wind
Therapeutic effect the most preferable.At present, also not from the basic etiological analysis of acute infantile convulsion wind, it is possible to the most dialectical control
Treat the pure Chinese medicine oral liquid of acute infantile convulsion wind.
Summary of the invention
It is an object of the invention to for the problems referred to above or defect, it is provided that the preparation of a kind of oral liquid treating acute infantile convulsion wind
Method, it is possible to the most effectively treatment acute infantile convulsion wind, cure rate is high, is difficult to recurrence, has no side effect.
Other purposes with some for achieving the above object, the present invention adopts the following technical scheme that
The preparation method of a kind of oral liquid treating acute infantile convulsion wind, wherein, comprises the following steps:
Step 1, extraction, by Chinese medicine composition drying and crushing, obtain raw material powder, and described Chinese medicine composition mainly includes following
The raw material of weight portion: Concha Erosariae seu Cypraeae 5-7, Rhizoma Phragmitis 12-15, Plumula Nelumbinis 13-15, Herba Potentillae Chinensis 8-12, Rhizoma Coptidis 4-6, Rhizoma Bolbostematis 6-8,
Radix Isatidis 8-12, Cornu Bubali 8-12, Herba Inulae 3-5, Fructus Trichosanthis 2-4, Thallus Laminariae (Thallus Eckloniae) 2-4, Sargassum 2-4, Concha Arcae 4-6, Rhizoma Gastrodiae 8-10, hook
Rattan 8-10, Arillus Longan 13-15, Radix Angelicae Sinensis 8-12, Caulis Spatholobi 8-12, Fructus Mori 8-12, Rhizoma Atractylodis Macrocephalae 10-14, Semen Lablab Album 8-12, Rhizoma Dioscoreae
23-25, Radix Pseudostellariae 8-12, Rhizoma Acori Graminei 2-4, Cortex Albiziae 8-10 and Caulis Polygoni Multiflori 8-10.
Step 2, raw material powder mixing with the 65-75% ethanol solution of 10-30 times of volume extraction, extraction terminates post-heating to be made
Ethanol evaporation, obtains extract.
Step 3, extract is added distilled water diluting 5-8 times, obtain the oral liquid of described treatment acute infantile convulsion wind.
Preferably, in the preparation method of the oral liquid of described treatment acute infantile convulsion wind, Chinese drug-treated group described in step one
Compound mainly includes the raw material of following weight portion:
Concha Erosariae seu Cypraeae 6, Rhizoma Phragmitis 9, Plumula Nelumbinis 14, Herba Potentillae Chinensis 10, Rhizoma Coptidis 5, Rhizoma Bolbostematis 7, Radix Isatidis 10, Cornu Bubali 10, gold Buddhist
Grass 4, Fructus Trichosanthis 3, Thallus Laminariae (Thallus Eckloniae) 3, Sargassum 3, Concha Arcae 5, Rhizoma Gastrodiae 9, Ramulus Uncariae Cum Uncis 9, Arillus Longan 14, Radix Angelicae Sinensis 10, Caulis Spatholobi 10, Fructus Mori 10, white
Art 12, Semen Lablab Album 10, Rhizoma Dioscoreae 24, Radix Pseudostellariae 10, Rhizoma Acori Graminei 3, Cortex Albiziae 9 and Caulis Polygoni Multiflori 9;
Preferably, in the preparation method of the oral liquid of described treatment acute infantile convulsion wind, anxious to treatment children's in step 3
The oral liquid of infantile convulsion adds the Mel of 5-8%.
The present invention at least includes following beneficial effect: first, and the present invention utilizes the traditional Chinese medical science five elements and dialectical theory, it is believed that children's
The cause of disease of acute infantile convulsion is that liver heresy is had a surplus and raw wind heat, the raw expectorant of heat, and expectorant heat visitor is between heart diaphragm, then wind-fire is fought mutually, therefore its card is anxious sudden and violent, strong
Heat-phlegm is stopped up, and alters regarding anti-sheet, and vibration of twitching, gnathospasma, the red red lip of cheek, this stagnation of liver-QI wind heat of floating pulse flood number, for the card of overabundance of YANG leading to deficiency of YIN.
Control fire of preferably dispelling be monarch, suitable cool preferably clear, eliminate the phlegm as minister, preferably drop, help with liver nourishing blood, support temper, calmness of having one's ideas straightened out.
In the present invention, Concha Erosariae seu Cypraeae, tranquillizing and allaying excitement, liver heat removing and eyesight improving;Rhizoma Phragmitis, heat clearing away, relieving restlessness;Plumula Nelumbinis, bitter in the mouth, clears away heart-fire, becomes
Heat;Herba Potentillae Chinensis, heat-clearing and toxic substances removing, conscience of dispelling fire;Rhizoma Coptidis, eliminating fire and detoxication, heat clearing and damp drying;Rhizoma Bolbostematis, heat-clearing and toxic substances removing, mass dissipating and swelling eliminating;
Radix Isatidis, capable of clearing heat and reducing internal heat, removing toxic substances, removing heat from blood;Cornu Bubali, eliminating fire and detoxication, arresting convulsion of calming the nerves;Herba Inulae, heat clearing away is eliminated the phlegm;Fructus Trichosanthis, lung heat clearing
Reduce phlegm, promoting the circulation of QI the chest stuffiness relieving;Thallus Laminariae (Thallus Eckloniae), Sargassum, eliminating phlegm and softening indurated mass;Concha Arcae, expectorant blood stasis dispelling, hard masses softening and resolving;Rhizoma Gastrodiae, endogenous wind stopping relieving convulsion, suppressing the hyperactive liver
YANG hyperactivity suppressing;Ramulus Uncariae Cum Uncis, endogenous wind stopping relieving convulsion, heat clearing away suppressing the hyperactive liver;Arillus Longan, liver nourishing blood, foster temper;Radix Angelicae Sinensis, blood-supplementing blood-nourishing;Caulis Spatholobi, promoting the circulation of blood is mended
Blood, dispelling wind and removing obstruction in the collateral;Fructus Mori, nourishing YIN and supplementing blood, breath wind syndrome caused by deficiency;The Rhizoma Atractylodis Macrocephalae, spleen invigorating QI invigorating, calms the nerves;Semen Lablab Album, invigorating the spleen for eliminating dampness;Rhizoma Dioscoreae, preferably gas
Yin nourishing, spleen reinforcing lung kidney;Radix Pseudostellariae, QI invigorating supports temper;Rhizoma Acori Graminei, has one's ideas straightened out, allays excitement, removing dampness to restore normal function of the stomach;Cortex Albiziae, resolving depression of calming the nerves, opens
Key is calm;Caulis Polygoni Multiflori, tranquilizing by nourishing the heart, dredging collateral.The present invention is by the reasonable compatibility of above plurality of Chinese, and fire of dispelling is monarch, Yi Liangyi
Clearly, eliminate the phlegm as minister, preferably drop, help with liver nourishing blood, support temper, calmness of having one's ideas straightened out, so that acute infantile convulsion wind is cured.
Secondly, by by can effectively treat acute infantile convulsion wind Chinese medicine composition carry out alcohol steep, make prepared
The oral liquid not only taking convenience for the treatment of acute infantile convulsion wind, and the absorption of beneficially effective ingredient, effectively treat children's
Acute infantile convulsion.
The present invention, according to clinical 100 example patient view statistics, divides 2-4 time with 30-50 milliliter consumption every day and takes, often
Within 5-7 days, being a course for the treatment of, cure rate 89%, total effective rate is up to 95%.
Part is embodied by the further advantage of the present invention, target and feature by description below, and part also will be by this
Invention research and practice and be understood by the person skilled in the art.
Detailed description of the invention
Below the present invention is elaborated, with make those of ordinary skill in the art refer to can be real according to this after this specification
Execute.
The preparation method of a kind of oral liquid treating acute infantile convulsion wind, comprises the following steps:
Step 1, extraction, by Chinese medicine composition drying and crushing, obtain raw material powder, and described Chinese medicine composition mainly includes following
The raw material of weight portion: Concha Erosariae seu Cypraeae 5-7, Rhizoma Phragmitis 12-15, Plumula Nelumbinis 13-15, Herba Potentillae Chinensis 8-12, Rhizoma Coptidis 4-6, Rhizoma Bolbostematis 6-8,
Radix Isatidis 8-12, Cornu Bubali 8-12, Herba Inulae 3-5, Fructus Trichosanthis 2-4, Thallus Laminariae (Thallus Eckloniae) 2-4, Sargassum 2-4, Concha Arcae 4-6, Rhizoma Gastrodiae 8-10, hook
Rattan 8-10, Arillus Longan 13-15, Radix Angelicae Sinensis 8-12, Caulis Spatholobi 8-12, Fructus Mori 8-12, Rhizoma Atractylodis Macrocephalae 10-14, Semen Lablab Album 8-12, Rhizoma Dioscoreae
23-25, Radix Pseudostellariae 8-12, Rhizoma Acori Graminei 2-4, Cortex Albiziae 8-10 and Caulis Polygoni Multiflori 8-10.
Step 2, raw material powder mixing with the 65-75% ethanol solution of 10-30 times of volume extraction, extraction terminates post-heating to be made
Ethanol evaporation, obtains extract.
Step 3, extract is added distilled water diluting 5-8 times, obtain the oral liquid of described treatment acute infantile convulsion wind.
The present invention utilizes the traditional Chinese medical science five elements and dialectical theory, it is believed that the cause of disease of acute infantile convulsion wind is that liver heresy is had a surplus and raw wind heat,
The raw expectorant of heat, expectorant heat visitor is between heart diaphragm, then wind-fire is fought mutually, therefore its card is anxious sudden and violent, and high fever expectorant is stopped up, and alters regarding anti-sheet, and vibration of twitching, mandibular joint is tight
Closing, the red red lip of cheek, this stagnation of liver-QI wind heat of floating pulse flood number, for the card of overabundance of YANG leading to deficiency of YIN.Control fire of preferably dispelling be monarch, suitable cool preferably clear, eliminate the phlegm into minister,
Preferably drop, help with liver nourishing blood, support temper, calmness of having one's ideas straightened out.
The concrete pharmacology of the present invention is:
Concha Erosariae seu Cypraeae, tranquillizing and allaying excitement, liver heat removing and eyesight improving;
Rhizoma Phragmitis, heat clearing away, relieving restlessness;
Plumula Nelumbinis, bitter in the mouth, clears away heart-fire, warms up;
Herba Potentillae Chinensis, heat-clearing and toxic substances removing, conscience of dispelling fire;
Rhizoma Coptidis, eliminating fire and detoxication, heat clearing and damp drying;
Rhizoma Bolbostematis, heat-clearing and toxic substances removing, mass dissipating and swelling eliminating;
Radix Isatidis, capable of clearing heat and reducing internal heat, removing toxic substances, removing heat from blood;
Cornu Bubali, eliminating fire and detoxication, arresting convulsion of calming the nerves;
Herba Inulae, heat clearing away is eliminated the phlegm;
Fructus Trichosanthis, removing heat from the lung and dissipating phlegm, promoting the circulation of QI the chest stuffiness relieving;
Thallus Laminariae (Thallus Eckloniae), Sargassum, eliminating phlegm and softening indurated mass;
Concha Arcae, expectorant blood stasis dispelling, hard masses softening and resolving;
Rhizoma Gastrodiae, endogenous wind stopping relieving convulsion, suppressing the hyperactive liver and subsiding YANG;
Ramulus Uncariae Cum Uncis, endogenous wind stopping relieving convulsion, heat clearing away suppressing the hyperactive liver;
Arillus Longan, liver nourishing blood, foster temper;
Radix Angelicae Sinensis, blood-supplementing blood-nourishing;
Caulis Spatholobi, promoting the circulation of blood is enriched blood, dispelling wind and removing obstruction in the collateral;
Fructus Mori, nourishing YIN and supplementing blood, breath wind syndrome caused by deficiency;
The Rhizoma Atractylodis Macrocephalae, spleen invigorating QI invigorating, calms the nerves;
Semen Lablab Album, invigorating the spleen for eliminating dampness;
Rhizoma Dioscoreae, preferably gas yin nourishing, spleen reinforcing lung kidney;
Radix Pseudostellariae, QI invigorating supports temper;
Rhizoma Acori Graminei, has one's ideas straightened out, allays excitement, removing dampness to restore normal function of the stomach;
Cortex Albiziae, resolving depression of calming the nerves, calmness of having one's ideas straightened out;
Caulis Polygoni Multiflori, tranquilizing by nourishing the heart, dredging collateral.
The present invention is by the reasonable compatibility of above plurality of Chinese, and fire of dispelling is monarch, suitable cool preferably clear, eliminates the phlegm as minister, preferably drops, help with
Liver nourishing blood, foster temper, calmness of having one's ideas straightened out, so that acute infantile convulsion wind is cured.
Embodiment 1
The preparation method of a kind of oral liquid treating acute infantile convulsion wind, comprises the following steps:
Step 1, extraction, by Chinese medicine composition drying and crushing, obtain raw material powder, and described Chinese medicine composition mainly includes following
The raw material of weight portion: Herba clinopodii confinis (Herba Clinopodii Gracilis) 10, Radix Mussaendae 15, Herba Menthae 15, Fructus Arctii 10, Folium Ilicis 10, Herba Equiseti Hiemalis 5, Radix Puerariae 8, Rhizoma Cimicifugae 8,
Rhizoma Coptidis 5, Radix Scutellariae 10, Herba Andrographis 10, Budgerigar dish 10, Herba Lophatheri 10, Poria 10, Rhizoma Alismatis 10, Exocarpium Benincasae 10, Flos Lonicerae 10, Baphicacanthus cusia
Root 10, Rhizoma Phragmitis 10, Radix Scrophulariae 10, the Radix Astragali 10, Semen Lablab Album 10, Radix Adenophorae (Radix Glehniae) 10 and Radix Ophiopogonis 5.
Step 2, by 70% ethanol solution mixing extraction of raw material powder and 20 times of volumes, extraction terminates post-heating makes ethanol steam
Send out, obtain extract.
Step 3, extract is added distilled water diluting 6 times, obtain the oral liquid of described treatment acute infantile convulsion wind.
Embodiment 2
The preparation method of a kind of oral liquid treating acute infantile convulsion wind, comprises the following steps:
Step 1, extraction, by Chinese medicine composition drying and crushing, obtain raw material powder, and described Chinese medicine composition mainly includes following
The raw material of weight portion: Concha Erosariae seu Cypraeae 6, Rhizoma Phragmitis 9, Plumula Nelumbinis 14, Herba Potentillae Chinensis 10, Rhizoma Coptidis 5, Rhizoma Bolbostematis 7, Radix Isatidis 10, Cornu Bubali 10,
Herba Inulae 4, Fructus Trichosanthis 3, Thallus Laminariae (Thallus Eckloniae) 3, Sargassum 3, Concha Arcae 5, Rhizoma Gastrodiae 9, Ramulus Uncariae Cum Uncis 9, Arillus Longan 14, Radix Angelicae Sinensis 10, Caulis Spatholobi 10, Fructus Mori
10, the Rhizoma Atractylodis Macrocephalae 12, Semen Lablab Album 10, Rhizoma Dioscoreae 24, Radix Pseudostellariae 10, Rhizoma Acori Graminei 3, Cortex Albiziae 9 and Caulis Polygoni Multiflori 9.
Step 2, by 68% ethanol solution mixing extraction of raw material powder and 25 times of volumes, extraction terminates post-heating makes ethanol steam
Send out, obtain extract.
Step 3, extract adding distilled water diluting 7 times, adding mass percent is the Mel of 5-8%, obtain described in control
Treat the oral liquid of acute infantile convulsion wind.
For proving the clinical efficacy of the oral liquid for the treatment of acute infantile convulsion wind of the present invention further, select 100 patients
Carry out clinical observation.In 100 example clinical patients, minimum 1 years old of age, maximum 7 years old, 4 years old mean age.
1, the standard of curative effect evaluation:
Cure: acute infantile convulsion wind transference cure, do not recur in 1 year.
Effective: during outbreak, acute infantile convulsion wind symptom substantially alleviates, and in 1 year, attack times significantly reduces.
Effective: during outbreak, acute infantile convulsion wind symptom alleviates before relatively treating, and in 1 year, attack times relatively treats front minimizing.
Invalid: the performance that the state of an illness is without any improvement.
2, therapeutic scheme:
The most described oral liquid 30-50 milliliter, divides and takes for 2-4 time, within every 5-7 days, be a course for the treatment of, take 2-5
The individual course for the treatment of.
3, therapeutic effect statistics:
Through clinical treatment and statistics, 89 people cure, effective 4 examples, effective 2 examples, invalid 5 examples, cure rate 89%, total effective rate
95%.
Although embodiment of the present invention are disclosed as above, but it is not restricted in description and embodiment listed
Using, it can be applied to various applicable the field of the invention completely, for those skilled in the art, and can be easily
Realizing other amendment, therefore under the general concept limited without departing substantially from claim and equivalency range, the present invention does not limit
In specific details.
Claims (3)
1. treat a preparation method for the oral liquid of acute infantile convulsion wind, wherein, comprise the following steps:
Step 1, extraction, by Chinese medicine composition drying and crushing, obtain raw material powder, and described Chinese medicine composition mainly includes following weight
The raw material of part: Concha Erosariae seu Cypraeae 5-7, Rhizoma Phragmitis 12-15, Plumula Nelumbinis 13-15, Herba Potentillae Chinensis 8-12, Rhizoma Coptidis 4-6, Rhizoma Bolbostematis 6-8, Baphicacanthus cusia
Root 8-12, Cornu Bubali 8-12, Herba Inulae 3-5, Fructus Trichosanthis 2-4, Thallus Laminariae (Thallus Eckloniae) 2-4, Sargassum 2-4, Concha Arcae 4-6, Rhizoma Gastrodiae 8-10, Ramulus Uncariae Cum Uncis 8-
10, Arillus Longan 13-15, Radix Angelicae Sinensis 8-12, Caulis Spatholobi 8-12, Fructus Mori 8-12, Rhizoma Atractylodis Macrocephalae 10-14, Semen Lablab Album 8-12, Rhizoma Dioscoreae 23-25,
Radix Pseudostellariae 8-12, Rhizoma Acori Graminei 2-4, Cortex Albiziae 8-10 and Caulis Polygoni Multiflori 8-10;
Step 2, raw material powder mixing with the 65-75% ethanol solution of 10-30 times of volume extraction, extraction terminates post-heating makes ethanol
Evaporation, obtains extract;
Step 3, extract is added distilled water diluting 5-8 times, obtain the oral liquid of described treatment acute infantile convulsion wind.
2. the preparation method of the oral liquid for the treatment of acute infantile convulsion wind as claimed in claim 1, wherein, Chinese medicine described in step one
Compositions mainly includes the raw material of following weight portion:
Concha Erosariae seu Cypraeae 6, Rhizoma Phragmitis 9, Plumula Nelumbinis 14, Herba Potentillae Chinensis 10, Rhizoma Coptidis 5, Rhizoma Bolbostematis 7, Radix Isatidis 10, Cornu Bubali 10, Herba Inulae 4,
Fructus Trichosanthis 3, Thallus Laminariae (Thallus Eckloniae) 3, Sargassum 3, Concha Arcae 5, Rhizoma Gastrodiae 9, Ramulus Uncariae Cum Uncis 9, Arillus Longan 14, Radix Angelicae Sinensis 10, Caulis Spatholobi 10, Fructus Mori 10, the Rhizoma Atractylodis Macrocephalae 12,
Semen Lablab Album 10, Rhizoma Dioscoreae 24, Radix Pseudostellariae 10, Rhizoma Acori Graminei 3, Cortex Albiziae 9 and Caulis Polygoni Multiflori 9.
3. the preparation method of the oral liquid for the treatment of acute infantile convulsion wind as claimed in claim 1 is wherein, little to treatment in step 3
The oral liquid of youngster's acute infantile convulsion adds the Mel of 5-8%.
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