CN106236777A - A kind of new Colla Corii Asini - Google Patents

A kind of new Colla Corii Asini Download PDF

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Publication number
CN106236777A
CN106236777A CN201610635152.8A CN201610635152A CN106236777A CN 106236777 A CN106236777 A CN 106236777A CN 201610635152 A CN201610635152 A CN 201610635152A CN 106236777 A CN106236777 A CN 106236777A
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China
Prior art keywords
parts
corii asini
colla corii
sus domestica
gained
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CN201610635152.8A
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Chinese (zh)
Inventor
杨福安
王京娥
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SHANDONG FUJIAO GROUP DONGE TOWN DONKEY-HIDE GELATIN Co Ltd
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SHANDONG FUJIAO GROUP DONGE TOWN DONKEY-HIDE GELATIN Co Ltd
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Priority to CN201610635152.8A priority Critical patent/CN106236777A/en
Publication of CN106236777A publication Critical patent/CN106236777A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cell Biology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

A kind of new Colla Corii Asini, is made up of the raw material of following parts by weight: Corii Sus domestica 2,500 3500 parts, 10 20 parts of crystal sugar, 10 15 parts of Oleum Glycines, 26 parts of Shaoxing rice wine.The present invention is compared to Colla Corii Asini, the new Colla Corii Asini cost using Corii Sus domestica to obtain as raw material production is low, raw hides is more rich to be easy to get, the most close with Colla Corii Asini to several hemopathic therapeutic effect, and it being used for treating anemia, essential thrombocytopenia, dysfunctional uterine hemorrhage, aplastic anemia, the curative effect of new Colla Corii Asini is better than Colla Corii Asini.

Description

A kind of new Colla Corii Asini
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of new Colla Corii Asini.
Background technology
Colla Corii Asini is the dried bark by equine species donkey or Cortex Dictamni boils and forms.Show according to state's livestock statistical yearbook, China donkey Breeding stock, by 11,000,000 of the nineties in last century, slips down to current 6,000,000, and also with the number of annual about 300,000 Amount declines, and is available for the donkey skin of glue year, only enough realizes about the sixty percent of Current production.Corii Sus domestica is medicine-food two-purpose animal material, valency Lattice are cheap, wide material sources, therefore replace donkey skin glue both can make up insufficient raw material with Corii Sus domestica, have again the multiple merit of Colla Corii Asini concurrently Effect, and low cost, be beneficial to promote.
The medicinal history of Corii Sus domestica glue just had begun to before bright.Later Han Dynasty's Zhang Zhongjing " the few cloudy piece of Treatise on Febrile Diseases " cloud: " few YIN diseasei, lower sore-throat relieving pain, fullness in the chest is vexed, and Corii Sus domestica soup boils it." Golden Mirror of Medicine side's solution says: " Corii Sus domestica person is to remove from office outer skin skin also." Lee Time treasure's Compendium of Material Medica cloud: " all make all glue, between October to two, March, useCattle, Babalus bubalis L., donkey skin person are upper, pig, horse, mule, Camel skin person take second place.”
1976, Pingyin Donkey-Hide Gelatin Factory, Shandong's (being positioned at present Donga town), on the basis of Colla Corii Asini processing technology, was developed into Merit " the new Colla Corii Asini " that make for raw material with Corii Sus domestica.Through 20 Duo Ge medical institutions clinic trial more than 1400 examples, it was demonstrated that to several blood The sick therapeutic effect of liquid is the most close with Colla Corii Asini, and be used for treating anemia, essential thrombocytopenia, dysfunctional uterine go out Blood, aplastic anemia, the curative effect of new Colla Corii Asini is better than Colla Corii Asini.But what kind of component and how to boil new Colla Corii Asini and could send out Wave the curative effect of new Colla Corii Asini, not systematic research.
Summary of the invention
It is an object of the invention to provide the new Colla Corii Asini that a kind of Corii Sus domestica boils, cost is low, has YIN nourishing, enriches blood and merit of stopping blooding Effect, weak to blood deficiency, menoxenia therapeutic effect is good, and haematemesiss, epistaxis, platelet and leukopenia are had obvious curative effects, solution Determine problems of the prior art.
The present invention solves that above-mentioned technical problem be the technical scheme is that
A kind of new Colla Corii Asini, is made up of the raw material of following parts by weight: Corii Sus domestica 2500-3500 part, crystal sugar 10-20 part, Oleum Glycines 10-15 part, Shaoxing rice wine 2-6 part.
Preferably, it is made up of the raw material of following parts by weight: Corii Sus domestica 3000 parts, 15 parts of crystal sugar, 12.5 parts of Oleum Glycines, Shaoxing rice wine 4 Part.
The preparation method of a kind of new Colla Corii Asini comprises the steps:
S1, selecting and weigh qualified Corii Sus domestica, Cortex Dictamni scrapes off oils and fats and hair, puts into wash and cleans standby in skin pond, and dried bark is direct Put into bubble Pi Chizhong, soak 4-5 day, change water 1-2 time every day, take out after soaking, unhairing;
S2, gained Corii Sus domestica in S1 is cut into 30-50cm square;
S3, gained Corii Sus domestica square in S2 is placed in Xi Pichi clean;
S4, clean for gained in S3 skin is put into rotary spherical digester Pi Jizhong, adds the water of 1:0.4, ventilation to pressure at 0.12- 0.20Mpa, extracts glue juice 3-5h, and glue juice precipitates 4-5h in settling box, is so repeated twice, takes supernatant in concentration pan Middle evaporation, concentrate, carry oil and carry foam;
S5, by gained liquid concentration in S4 to shovel provoke extension pearl after, add the crystal sugar of corresponding amount, Oleum Glycines, Shaoxing rice wine in dispensing, continue Continuous being concentrated into when provoking extension flag with shovel, inclined to by glue in gel box, gel rear cutout becomes the fritter of regulatory specifications;
S6, by surface being wiped to light, ultraviolet radiation sterilization after in S5, gained fritter dries in the shade, then pack.
Usage and dosage: once-a-day, one time 9-15 gram.
Compared with prior art, the invention have the advantage that compared to Colla Corii Asini, use Corii Sus domestica as raw material production obtain new Colla Corii Asini cost is low, and raw hides is more rich to be easy to get, the most close with Colla Corii Asini to several hemopathic therapeutic effect, and is used for controlling Treating anemia, essential thrombocytopenia, dysfunctional uterine hemorrhage, aplastic anemia, the curative effect of new Colla Corii Asini is better than Colla Corii Asini.
Detailed description of the invention
For the technical characterstic of this programme can be clearly described, below by detailed description of the invention, the present invention is explained in detail State.
Embodiment 1
A kind of new Colla Corii Asini, is made up of the raw material of following weight: Corii Sus domestica 2500kg, crystal sugar 10kg, Oleum Glycines 10kg, Shaoxing rice wine 2kg.
Preparation method is as follows:
S1, select and weigh qualified dry Corii Sus domestica, direct plunge into bubble Pi Chizhong, soak 4, change water every day 1 time, after soaking Take out, unhairing;
S2, gained Corii Sus domestica in S1 is cut into 30cm square;
S3, gained Corii Sus domestica square in S2 is placed in Xi Pichi clean;
S4, clean for gained in S3 skin being put into rotary spherical digester Pi Jizhong, add the water of 1:0.4, ventilation, carries to pressure at 0.12Mpa Taking glue juice 3h, glue juice precipitates 4h in settling box, is so repeated twice, takes supernatant and evaporates in concentration pan, concentrates, carries Oil carries foam;
S5, by gained liquid concentration in S4 to shovel provoke extension pearl after, add dispensing crystal sugar, Oleum Glycines, Shaoxing rice wine, continue to be concentrated into use When extension flag provoked by shovel, being inclined to by glue in gel box, gel rear cutout becomes the fritter of regulatory specifications;
S6, by surface being wiped to light, ultraviolet radiation sterilization after in S5, gained fritter dries in the shade, then pack.
Usage and dosage: once-a-day, a 9-15g.
Embodiment 2
A kind of new Colla Corii Asini, is made up of the raw material of following weight: Corii Sus domestica 3500kg, crystal sugar 20kg, Oleum Glycines 15kg, Shaoxing rice wine 6kg.
Preparation method is as follows:
S1, select and weigh qualified fresh pig skin, scrape off oils and fats and hair, put into wash skin pond is cleaned standby;
S2, gained Corii Sus domestica in S1 is cut into 50cm square;
S3, gained Corii Sus domestica square in S2 is placed in Xi Pichi clean;
S4, clean for gained in S3 skin being put into rotary spherical digester Pi Jizhong, add the water of 1:0.4, ventilation, carries to pressure at 0.20Mpa Taking glue juice 5h, glue juice precipitates 5h in settling box, is so repeated twice, takes supernatant and evaporates in concentration pan, concentrates, carries Oil carries foam;
S5, by gained liquid concentration in S4 to shovel provoke extension pearl after, with crystal sugar, Oleum Glycines, Shaoxing rice wine, continue to be concentrated into and choose with shovel When playing extension flag, being inclined to by glue in gel box, gel rear cutout becomes the fritter of regulatory specifications;
S6, by surface being wiped to light, ultraviolet radiation sterilization after in S5, gained fritter dries in the shade, then pack.
Usage and dosage: once-a-day, a 9-15g.
Embodiment 3
A kind of new Colla Corii Asini is made up of the raw material of following weight: Corii Sus domestica 3000kg, crystal sugar 15kg, Oleum Glycines 12.5kg, Shaoxing rice wine 4kg。
Preparation method is as follows:
S1, select and weigh qualified dry Corii Sus domestica, direct plunge into bubble Pi Chizhong, soak 5, change water every day 2 times, after soaking Take out, unhairing;
S2, gained Corii Sus domestica in S1 is cut into 40cm square;
S3, gained Corii Sus domestica square in S2 is placed in Xi Pichi clean;
S4, clean for gained in S3 skin being put into rotary spherical digester Pi Jizhong, add the water of 1:0.4, ventilation, carries to pressure at 0.16Mpa Taking glue juice 4h, glue juice precipitates 5h in settling box, is so repeated twice, takes supernatant and evaporates in concentration pan, concentrates, carries Oil carries foam;
S5, by gained liquid concentration in S4 to shovel provoke extension pearl after, with crystal sugar, Oleum Glycines, Shaoxing rice wine, continue to be concentrated into and choose with shovel When playing extension flag, being inclined to by glue in gel box, gel rear cutout becomes the fritter of regulatory specifications;
S6, by surface being wiped to light, ultraviolet radiation sterilization after in S5, gained fritter dries in the shade, then pack.
Usage and dosage: once-a-day, a 9-15g.
Model case:
Case 1: Lee, female, 58 years old, physical weakness, myasthenia of limbs, anemia, take the new Colla Corii Asini that embodiment 1 is made, two After individual month, Anemia alleviates, and health is strongr than before, and after continuing edible tri month, Anemia is wholly absent, in vigorous health, Extremity are strong.
Case 2: revive so-and-so, female, 65 years old, dizzy unable, lower limb distributed ecchymosis, suffer from thrombocytopenia, take reality Executing the new Colla Corii Asini after three months of example 2 preparation, transference cure, ecchymosis disappears, evident in efficacy.
Case 3: journey so-and-so, female, 35 years old, dizzy nervous, inappetence, general weakness, sometimes gingival hemorrhage, complexion, mouth Lip is the palest, is diagnosed as reproducibility obstacle anemia, takes the new Colla Corii Asini (in conjunction with integrative therapy) of embodiment 3 preparation, takes altogether Three months, subjective symptoms disappeared.
Case 4: model so-and-so, female, 40 years old, more than leukopenia half a year, dizzy weak, it is impossible to adhere to work, long period Half-day rest, takes the new Colla Corii Asini after month of embodiment 3 preparation certainly, and leukocyte substantially rises, and spirit takes a turn for the better, and dizziness alleviates, can be hard Hold whole day working.
Above-mentioned detailed description of the invention cannot function as limiting the scope of the invention, for the technology people of the art For Yuan, any alternate modification being made embodiment of the present invention or conversion all fall within protection scope of the present invention.
The present invention does not describes part in detail, is the known technology of those skilled in the art of the present technique.

Claims (3)

1. a new Colla Corii Asini, it is characterised in that be made up of the raw material of following parts by weight: Corii Sus domestica 2500-3500 part, crystal sugar 10- 20 parts, Oleum Glycines 10-15 part, Shaoxing rice wine 2-6 part.
The new Colla Corii Asini of one the most according to claim 1, it is characterised in that be made up of the raw material of following parts by weight: Corii Sus domestica 3000 parts, 15 parts of crystal sugar, 12.5 parts of Oleum Glycines, 4 parts of Shaoxing rice wine.
The new Colla Corii Asini of one the most according to claim 1, it is characterised in that preparation method comprises the steps:
S1, selecting and weigh qualified Corii Sus domestica, Cortex Dictamni scrapes off oils and fats and hair, puts into wash and cleans standby in skin pond, and dried bark direct plunges into Bubble Pi Chizhong, soaks 4-5 day, changes water 1-2 time every day, takes out, unhairing after soaking;
S2, gained Corii Sus domestica in S1 is cut into 30-50cm square;
S3, gained Corii Sus domestica square in S2 is placed in Xi Pichi clean;
S4, clean for gained in S3 skin being put into rotary spherical digester Pi Jizhong, add the water of 1:0.4, ventilation, carries to pressure at 0.12-0.20Mpa Taking glue juice 3-5h, glue juice precipitates 4-5h in settling box, is so repeated twice, take supernatant evaporate in concentration pan, dense Contracting, carry oil and carry foam;
S5, by gained liquid concentration in S4 to shovel provoke extension pearl after, add the crystal sugar of corresponding amount, Oleum Glycines, Shaoxing rice wine in dispensing, continue dense When being reduced to provoke extension flag with shovel, being inclined to by glue in gel box, gel rear cutout becomes the fritter of regulatory specifications;
S6, by surface being wiped to light, ultraviolet radiation sterilization after in S5, gained fritter dries in the shade, then pack.
CN201610635152.8A 2016-08-04 2016-08-04 A kind of new Colla Corii Asini Pending CN106236777A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107412268A (en) * 2016-12-29 2017-12-01 青海高原红绿色保健制品有限公司 A kind of Yak skin glue and preparation method thereof
CN109315767A (en) * 2018-08-31 2019-02-12 河北共永生物科技有限公司 A kind of formula and its preparation process of Islamic oxhide gelatin
CN110721200A (en) * 2019-12-03 2020-01-24 山东福牌阿胶股份有限公司 Application of donkey-hide gelatin and novel donkey-hide gelatin composition in preparation of medicines for preventing or treating diseases related to platelet reduction
CN110840916A (en) * 2019-12-03 2020-02-28 山东福牌阿胶股份有限公司 Application of composition of donkey-hide gelatin and new donkey-hide gelatin in preparation of antioxidant drugs
CN114129596A (en) * 2020-09-03 2022-03-04 洪立东 Liquid donkey-hide gelatin decocted from fish scales and pigskin

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103622999A (en) * 2013-10-31 2014-03-12 山东东阿阿胶股份有限公司 Method for rapidly producing donkey-hide gelatin
CN103784928A (en) * 2014-02-25 2014-05-14 山东东阿阿胶股份有限公司 Ass-hide glue paste with effects of clearing away lung-heat and moistening lung and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103622999A (en) * 2013-10-31 2014-03-12 山东东阿阿胶股份有限公司 Method for rapidly producing donkey-hide gelatin
CN103784928A (en) * 2014-02-25 2014-05-14 山东东阿阿胶股份有限公司 Ass-hide glue paste with effects of clearing away lung-heat and moistening lung and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
于平: "《传统技艺》", 31 August 2008 *
陈馥馨: "《新编中成药手册》", 31 March 1991 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107412268A (en) * 2016-12-29 2017-12-01 青海高原红绿色保健制品有限公司 A kind of Yak skin glue and preparation method thereof
CN109315767A (en) * 2018-08-31 2019-02-12 河北共永生物科技有限公司 A kind of formula and its preparation process of Islamic oxhide gelatin
CN110721200A (en) * 2019-12-03 2020-01-24 山东福牌阿胶股份有限公司 Application of donkey-hide gelatin and novel donkey-hide gelatin composition in preparation of medicines for preventing or treating diseases related to platelet reduction
CN110840916A (en) * 2019-12-03 2020-02-28 山东福牌阿胶股份有限公司 Application of composition of donkey-hide gelatin and new donkey-hide gelatin in preparation of antioxidant drugs
CN114129596A (en) * 2020-09-03 2022-03-04 洪立东 Liquid donkey-hide gelatin decocted from fish scales and pigskin

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Address after: 250401 Dong'e, Shandong, Pingyin Town, Ji'nan

Applicant after: Shandong Limited by Share Ltd donkey hide gelatin

Address before: 250401 Dong'e, Shandong, Pingyin Town, Ji'nan

Applicant before: Shandong Fujiao Group Donge Town Donkey-Hide Gelatin Co., Ltd.

CB03 Change of inventor or designer information
CB03 Change of inventor or designer information

Inventor after: Yang Hua

Inventor after: Wang Jinge

Inventor after: Yang Fuan

Inventor before: Yang Fuan

Inventor before: Wang Jinge

RJ01 Rejection of invention patent application after publication
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Application publication date: 20161221