CN106177318A - A kind of medicine treating insomnia - Google Patents

A kind of medicine treating insomnia Download PDF

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Publication number
CN106177318A
CN106177318A CN201610703412.0A CN201610703412A CN106177318A CN 106177318 A CN106177318 A CN 106177318A CN 201610703412 A CN201610703412 A CN 201610703412A CN 106177318 A CN106177318 A CN 106177318A
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gram
insomnia
fructus
medicine
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周舜宁
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/89Cyperaceae (Sedge family)
    • A61K36/8905Cyperus (flatsedge)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/14Cupressaceae (Cypress family), e.g. juniper or cypress
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/535Perilla (beefsteak plant)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/744Gardenia
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    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
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    • A61K36/88Liliopsida (monocotyledons)
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    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

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Abstract

The invention discloses a kind of medicine treating insomnia, be made up of following raw material: Radix Angelicae Sinensis 15 25 grams, Radix Ginseng 5 15 grams, Fructus Citri Sarcodactylis 10 30 grams, Semen Platycladi 5 15 grams, Fructus Schisandrae Chinensis 15 25 grams, Rhizoma Cyperi 6 10 grams, Rhizoma Pinelliae Preparatum 6 10 grams, Semen Ziziphi Spinosae 6 10 grams, Cortex Albiziae 10 15 grams, 10 15 grams of Flos Carthami, Concha Haliotidis 10 20 grams, Fructus Gardeniae 10 20 grams, Folium Perillae 15 25 grams.The present invention combines the mechanism of each crude drug component, carries out reaching the mediation of negative and positive in patient body by Chinese medicine preparation, obtains in conjunction with clinical trial for many years, has good effect for treatment insomnia.

Description

A kind of medicine treating insomnia
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of medicine treating insomnia.
Background technology
Insomnia refers to fall asleep and maybe cannot keep sleep state, causes not having enough sleep.Also known as falling asleep and maintaining sleep barrier Hindering (DlMS), insomnia is relatively big to the harm of health, its Symptoms be difficulty falling asleep or awake frequently, dreaminess, without sleeping Sleep and feel, sleep deep and early awakening, do not recover from fatigue after waking up.The traditional Chinese medical science is called again: be insomnia, insomnia, must not crouch, the unable to close the eyes, be with warp Chang Buneng obtains a kind of disease of being characterized of ortho sleep, for a variety of causes cause difficulty falling asleep, Depth of sleep or frequency too short, Early awakening and the length of one's sleep are not enough or of poor quality etc., and the common reason causing insomnia mainly has environment reason, individual factors, body former Cause, Nervous and Mental Factors, emotional factor etc..According to Traditional Chinese medical theory, it is in disorder that the reason of insomnia is mainly internal organs, the especially heart The YIN nourishing function of warming YANG function and kidney can not coordinate, deficiency of qi and blood, imbalance of YIN and YANG etc..
Insomnia is treated by Western medicine, rapid-action, effective, but the insomnia of long-term taking western medicine often produces resistance to The property of medicine and dependency, unfavorable to patient body, for the treatment of insomnia after being less useful for.
Summary of the invention
For above-mentioned, it is an object of the invention to provide a kind of evident in efficacy, short treating period, instant effect, that is free from side effects controls Treat the medicine of insomnia.
The present invention adopts the technical scheme that:
A kind of medicine treating insomnia, is made up of following raw material: Radix Angelicae Sinensis 15-25 gram, Radix Ginseng 5-15 gram, Fructus Citri Sarcodactylis 10-30 gram, Semen Platycladi 5-15 gram, Fructus Schisandrae Chinensis 15-25 gram, Rhizoma Cyperi 6-10 gram, Rhizoma Pinelliae Preparatum 6-10 gram, Semen Ziziphi Spinosae 6-10 gram, Herba Albiziae Skin 10-15 gram, 10-15 gram of Flos Carthami, Concha Haliotidis 10-20 gram, Fructus Gardeniae 10-20 gram, Folium Perillae 15-25 gram.
Preferably, the medicine of described treatment insomnia, it is made up of following raw material: Radix Angelicae Sinensis 20 grams, Radix Ginseng 10 grams, Buddhist Hands Citrus chachiensis Hort. 20 grams, Semen Platycladi 10 grams, Fructus Schisandrae Chinensis 20 grams, Rhizoma Cyperi 8 grams, Rhizoma Pinelliae Preparatum 8 grams, Semen Ziziphi Spinosae 8 grams, Cortex Albiziae 12.5 grams, Flos Carthami 12.5 grams, Concha Haliotidis 15 grams, Fructus Gardeniae 15 grams, Folium Perillae 20 grams.
The preparation method of said medicine is: after proportionally being mixed by each crude drug, adds immersion 1 in the water of 10 times little Time, it being heated to fluidized state and keep 1.5-2 hour, sucking filtration, filtrate is standby, and residue fills into 8 times amount water again, then it is little to boil 1.5-2 Time, sucking filtration, merge the filtrate decocting gained twice, obtain medicine.
The invention have the advantage that the present invention combines the mechanism of each crude drug component, carried out patient's body by Chinese medicine preparation The mediation of internal negative and positive reaches, and obtains in conjunction with clinical trial for many years, has good effect for treatment insomnia.
Detailed description of the invention
In order to make the purpose of the present invention, technical scheme and advantage clearer, below in conjunction with embodiment, to the present invention It is described in further detail.Should be appreciated that specific embodiment described herein, and need not only in order to explain the present invention In limiting invention.
Embodiment 1
A kind of medicine treating insomnia, is made up of following raw material: Radix Angelicae Sinensis 15 grams, Radix Ginseng 5 grams, Fructus Citri Sarcodactylis 10 grams, Semen Platycladi 5 grams, Fructus Schisandrae Chinensis 15 grams, Rhizoma Cyperi 6 grams, Rhizoma Pinelliae Preparatum 6 grams, Semen Ziziphi Spinosae 6 grams, Cortex Albiziae 10 grams, 10 grams of Flos Carthami, Concha Haliotidis 10 Gram, Fructus Gardeniae 10 grams, Folium Perillae 15 grams.
Preparation method is: after proportionally being mixed by each crude drug, adds in the water of 10 times and soaks 1 hour, is heated to Fluidized state keeps 1.5 hours, sucking filtration, and filtrate is standby, and residue fills into 8 times amount water again, then boils 1.5 hours, sucking filtration, merges two The filtrate of secondary decoction gained.
Embodiment 2
A kind of medicine treating insomnia, is made up of following raw material: Radix Angelicae Sinensis 20 grams, Radix Ginseng 10 grams, Fructus Citri Sarcodactylis 20 grams, Semen Platycladi 10 grams, Fructus Schisandrae Chinensis 20 grams, Rhizoma Cyperi 8 grams, Rhizoma Pinelliae Preparatum 8 grams, Semen Ziziphi Spinosae 8 grams, Cortex Albiziae 12.5 grams, 12.5 grams of Flos Carthami, stone Semen Cassiae 15 grams, Fructus Gardeniae 15 grams, Folium Perillae 20 grams.
Preparation method is: after proportionally being mixed by each crude drug, adds in the water of 10 times and soaks 1 hour, is heated to Fluidized state keeps 2 hours, and sucking filtration, filtrate is standby, and residue fills into 8 times amount water again, then boils 1.5 hours, sucking filtration, merges twice Decoct the filtrate of gained.
Embodiment 3
A kind of medicine treating insomnia, is made up of following raw material: Radix Angelicae Sinensis 25 grams, Radix Ginseng 15 grams, Fructus Citri Sarcodactylis 30 grams, Semen Platycladi 15 grams, Fructus Schisandrae Chinensis 25 grams, Rhizoma Cyperi 10 grams, Rhizoma Pinelliae Preparatum 10 grams, Semen Ziziphi Spinosae 10 grams, Cortex Albiziae 15 grams, 15 grams of Flos Carthami, Concha Haliotidis Bright 20 grams, Fructus Gardeniae 20 grams, Folium Perillae 25 grams.
Preparation method is: after proportionally being mixed by each crude drug, adds in the water of 10 times and soaks 1 hour, is heated to Fluidized state keeps 2 hours, sucking filtration, and filtrate is standby, and residue fills into 8 times amount water again, then boils 2 hours, sucking filtration, merges twice and decocts Boil the filtrate of gained.
Embodiment 4
Clinical observation
Physical data: the present inventor carried out clinical observation treatment to 35 example out-patients so far in 2015, the age 20 arrives 45 years old.
Therapeutic Method: every day potion, sleep front decoction being taken warmly at twice, 5 days is a course for the treatment of, takes 2-3 the course for the treatment of.
Efficacy assessment standard:
Cure: symptom and sign is wholly absent;
Effective: symptom and sign alleviates earlier above;
Invalid: symptom and sign is front with treatment without improving.
Therapeutic effect: clinical cure 32 example, accounts for 91.4%;Effective 3 examples, invalid 0 example, total effective rate 100%.
Model case
Wang, because stress is big, causes insomnia, over nearly more than 10 days, lies awake all night, have palpitation, breathe hard, cardiopalmus, dizziness, inspection Looking into discovery red tongue, arrhythmia, lethargy is depressed, confirms as moderate insomnia.Take medicine of the present invention just to take effect, continuously that night After taking 5 days, symptom and sign alleviates earlier above, and after taking 5 days the most continuously, insomnia is thoroughly cured, recurrence of following up a case by regular visits to that so far there are no.
Zhang, half a year, cause was quarreled with leader, caused insomnia, ate a lot of insomnia drug effect fruit bad, and confirmed as slightly losing Sleep.Main suit is muddled, dizzy, dreaminess, cardiopalmus, check find red tongue, heart jump fast.Give medicine of the present invention, take two treatments Fully recover after journey, recurrence of following up a case by regular visits to that so far there are no.

Claims (3)

1. the medicine treating insomnia, it is characterised in that be made up of following raw material: Radix Angelicae Sinensis 15-25 gram, Radix Ginseng 5-15 Gram, Fructus Citri Sarcodactylis 10-30 gram, Semen Platycladi 5-15 gram, Fructus Schisandrae Chinensis 15-25 gram, Rhizoma Cyperi 6-10 gram, Rhizoma Pinelliae Preparatum 6-10 gram, Semen Ziziphi Spinosae 6- 10 grams, Cortex Albiziae 10-15 gram, 10-15 gram of Flos Carthami, Concha Haliotidis 10-20 gram, Fructus Gardeniae 10-20 gram, Folium Perillae 15-25 gram.
The medicine for the treatment of insomnia the most according to claim 1, it is characterised in that be made up of following raw material: Radix Angelicae Sinensis 20 Gram, Radix Ginseng 10 grams, Fructus Citri Sarcodactylis 20 grams, Semen Platycladi 10 grams, Fructus Schisandrae Chinensis 20 grams, Rhizoma Cyperi 8 grams, Rhizoma Pinelliae Preparatum 8 grams, Semen Ziziphi Spinosae 8 grams, Herba Albiziae Skin 12.5 grams, 12.5 grams of Flos Carthami, Concha Haliotidis 15 grams, Fructus Gardeniae 15 grams, Folium Perillae 20 grams.
The medicine for the treatment of insomnia the most according to claim 1 and 2, it is characterised in that preparation method is: pressed by each crude drug After mixing according to ratio, add in the water of 10 times and soak 1 hour, be heated to fluidized state and keep 1.5-2 hour, sucking filtration, filtrate Standby, residue fills into 8 times amount water again, then boils 1.5-2 hour, sucking filtration, merges the filtrate decocting gained twice, obtains medicine.
CN201610703412.0A 2016-08-22 2016-08-22 A kind of medicine treating insomnia Pending CN106177318A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106924388A (en) * 2017-03-16 2017-07-07 杨本雷 It is a kind of to treat pharmaceutical composition of insomnia and preparation method thereof, preparation and application

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103816332A (en) * 2013-12-10 2014-05-28 济南新起点医药科技有限公司 Traditional Chinese medicine composition for treating insomnia caused by weakness of both heart and spleen
CN104873752A (en) * 2015-05-11 2015-09-02 杭州美誉医药有限公司 Traditional Chinese medicine preparation for treating insomnia, preparation method and application

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103816332A (en) * 2013-12-10 2014-05-28 济南新起点医药科技有限公司 Traditional Chinese medicine composition for treating insomnia caused by weakness of both heart and spleen
CN104873752A (en) * 2015-05-11 2015-09-02 杭州美誉医药有限公司 Traditional Chinese medicine preparation for treating insomnia, preparation method and application

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106924388A (en) * 2017-03-16 2017-07-07 杨本雷 It is a kind of to treat pharmaceutical composition of insomnia and preparation method thereof, preparation and application
CN106924388B (en) * 2017-03-16 2018-06-29 杨本雷 A kind of pharmaceutical composition for treating insomnia and preparation method thereof, preparation and application

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Application publication date: 20161207