CN106214839A - Many young granules and preparation method thereof - Google Patents
Many young granules and preparation method thereof Download PDFInfo
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Abstract
The invention discloses many young granules of one and preparation method thereof, Radix Dauci Sativae and Fructus Lycii in raw material use particular extraction procedure to propose effective ingredient, add natural plants and animal component again, part material is carried out pretreatment, the raw material of pretreatment can strengthen the effect of Chinese medicine extract and natural plant composition, the how young granule prepared is possible not only to improve reproduction of domesti animals function, and has certain opsonic action to the intestines and stomach.
Description
Technical field
The present invention relates to many young granules of one and preparation method thereof, belong to field of animal feed.
Background technology
Feedstuff, is the general name of the food of everyone domesticated animal, compares narrowly general feeds and generally refers to agricultural
Or the food of animal husbandry domesticated animal.Feedstuff include Semen sojae atricolor, bean cake, Semen Maydis, fish flour, aminoacid, the miscellaneous dregs of rice, additive, whey powder,
The feedstuff of more than ten kinds such as oils and fats, meat meal tankage, corn, sugar grass.
Animal feed is all directly to add various Chinese medicines, DeGrain at present.
Summary of the invention
It is an object of the invention to provide many young granules of one and preparation method thereof, Radix Dauci Sativae and Fructus Lycii in raw material use
Particular extraction procedure proposes effective ingredient, then adds natural plants and animal component, and part material is carried out pretreatment, pretreatment
Raw material can strengthen the effect of Chinese medicine extract and natural plant composition, it is numerous that prepared how young granules are possible not only to improve poultry
Grow function, and the intestines and stomach is had certain opsonic action.
A kind of many young granules, are made up of the raw material of following masses number: Chinese medicine extract 900-1000 part, vitamin C
50.10-50.30 part, vitamin E 20.50-20.70 part, carrier:
A kind of many young granules, are made up of the raw material of following masses number: Chinese medicine extract 900-1000 part, vitamin C
50.10-50.30 part, vitamin E 20.50-20.70 part, Semen Pisi sativi leaf 54-56 part, fish flour 17-19 part, Semen Raphani 26.5-27.5
Part, Rhizoma Polygonati 22.6-23.0 part, tryptophan 15-20 part, cobaltous sulfate 4.5-6.5 part, carnitine 6-8 part, propyl p-hydroxybenzoate
3.6-4.4 part, dibenzylatiooluene 7-9 part, white carbon 6-8 part, curcumin 5-6 part.
Described Chinese medicine extract is made up of the raw material of following masses number: Radix Dauci Sativae 29-30 part, Fructus Lycii 22.4-
23.8 parts.
The preparation method of Chinese medicine extract is:
(1) Fructus Lycii 40-50 DEG C of water-bath of ether of 9-11 times of quality is extracted 180-220 minute, filter, obtain filtering residue；
(2) filtering residue is added the distilled water of 20-21 times of quality to extract 4-5 hour under the conditions of 70-80 DEG C, be filtrated to get water and carry
Liquid；
(3) Aqueous extracts is centrifuged under the conditions of 1500-1700r/min, isolated supernatant；
(4) D113 ion exchange resin column on supernatant, upper column flow rate is 1.4-1.6BV/h, by 90% second of 3BV
Alcohol-acetone mixture, the 70% ethanol-acetone mixed liquor of 2BV, the 50% ethanol-acetone mixed liquor of 1BV carries out gradient successively and washes
De-, elution flow rate is 1.4-1.6BV/h, collects gradient eluent；
(5) the 1/3 of gradient eluent decompression and solvent recovery to original volume, it is dried, standby；
(6) Radix Dauci Sativae being pulverized, the extract obtained with upper step merges, and is Chinese medicine extract.
Wherein, in step (4), the volume ratio of supernatant and D113 ion exchange resin column is 2:1, the height of resin column and
Diameter ratio is for 8:1, and in 90% ethanol-acetone mixed liquor, the volume ratio of 90% ethanol and acetone is 4:1, and 70% ethanol-acetone mixes
Closing the volume of 70% ethanol and acetone in liquid is 3:1, and in 50% ethanol-acetone mixed liquor, the volume ratio of 50% ethanol and acetone is
2:1。
A kind of many young granules, its preparation method is:
(1) the Semen Raphani distilled water of 7-9 times of quality is decocted 50-70 minute, filter, obtain filtrate I and filtering residue I；
(2) filtering residue I and fish flour mix homogeneously, standby；
(3) Semen Pisi sativi leaf and Rhizoma Polygonati being joined in filtrate I, add 95% ethanol and make alcohol content be 30%, centrifugal, rotating speed is
800-900r/min, isolated precipitates；
(4) material that the precipitation that upper step is obtained obtains with (2) step is mixed homogeneously, with the distillation of gross mass 3-4 times
Water washs, and obtains pretreated raw material；
(5) Chinese medicine extract taking 1/4 mass is placed in mixer, adds pretreated raw material, vitamin C, dimension life
Element E, tryptophan, cobaltous sulfate, carnitine, propyl p-hydroxybenzoate, dibenzylatiooluene, white carbon, curcumin, mixing
20-30 minute, standby；
(6) taking remaining Chinese medicine extract to be placed in another mixer, add step (5) gained material, mixing 20-30 divides
Clock, subpackage, to obtain final product.
The solution have the advantages that:
1, Radix Dauci Sativae and Fructus Lycii use specific preparation method to obtain Chinese medicine extract, have effectively extracted improvement poultry
The composition of breeding function, effect is better than being provided without extracting method and the Radix Dauci Sativae of other extracting method and Fructus Lycii.
2, raw material uses Semen Pisi sativi leaf, fishbone powder, Semen Raphani and the Rhizoma Polygonati of plant animal composition, containing natural effective one-tenth
Point, have no side effect.
3, preparation process first carries out pretreatment Semen Pisi sativi leaf, fishbone powder, Semen Raphani and the Rhizoma Polygonati in raw material, then and other
Many young granules made by raw material.
4, the raw material of the pretreatment of the present invention can strengthen Chinese medicine extract and the effect of natural plants animal component, three
Combination, the how young granule prepared is possible not only to improve reproduction of domesti animals function, and has certain opsonic action to the intestines and stomach.
Detailed description of the invention
Below by embodiment, the invention will be further described.
Embodiment 1:
A kind of many young granules, are made up of the raw material of following masses number: Chinese medicine extract 900 parts, vitamin C 50.10
Part, vitamin E 20.50 parts, 54 parts of Semen Pisi sativi leaf, fish flour 17 parts, Semen Raphani 26.5 parts, Rhizoma Polygonati 22.6 parts, tryptophan 15 parts, sulfur
Acid cobalt 4.5 parts, carnitine 6 parts, propyl p-hydroxybenzoate 3.6 parts, dibenzylatiooluene 7 parts, white carbon 6 parts, ginger color
Element 5 parts.
Described Chinese medicine extract is made up of the raw material of following masses number: 29 parts of Radix Dauci Sativae, Fructus Lycii 22.4 parts.
The preparation method of Chinese medicine extract is:
(1) Fructus Lycii 40 DEG C of water-baths of ether of 9 times of quality are extracted 180 minutes, filter, obtain filtering residue；
(2) distilled water filtering residue being added 20 times of quality extracts 4 hours under the conditions of 70 DEG C, is filtrated to get Aqueous extracts；
(3) Aqueous extracts is centrifuged under the conditions of 1500r/min, isolated supernatant；
(4) D113 ion exchange resin column on supernatant, upper column flow rate is 1.4BV/h, with 90% ethanol-the third of 3BV
Ketone mixed liquor, the 70% ethanol-acetone mixed liquor of 2BV, the 50% ethanol-acetone mixed liquor of 1BV carries out gradient elution successively, washes
Separation of flow speed is 1.4BV/h, collects gradient eluent；
(5) the 1/3 of gradient eluent decompression and solvent recovery to original volume, it is dried, standby；
(6) Radix Dauci Sativae being pulverized, the extract obtained with upper step merges, and is Chinese medicine extract.
Wherein, in step (4), the volume ratio of supernatant and D113 ion exchange resin column is 2:1, the height of resin column and
Diameter ratio is for 8:1, and in 90% ethanol-acetone mixed liquor, the volume ratio of 90% ethanol and acetone is 4:1, and 70% ethanol-acetone mixes
Closing the volume of 70% ethanol and acetone in liquid is 3:1, and in 50% ethanol-acetone mixed liquor, the volume ratio of 50% ethanol and acetone is
2:1。
A kind of many young granules, its preparation method is:
(1) the Semen Raphani distilled water of 7 times of quality is decocted 50 minutes, filter, obtain filtrate I and filtering residue I；
(2) filtering residue I and fish flour mix homogeneously, standby；
(3) Semen Pisi sativi leaf and Rhizoma Polygonati being joined in filtrate I, add 95% ethanol and make alcohol content be 30%, centrifugal, rotating speed is
800r/min, isolated precipitates；
(4) material that the precipitation that upper step is obtained obtains with (2) step is mixed homogeneously, with the distilled water of gross mass 3 times
Washing, obtains pretreated raw material；
(5) Chinese medicine extract taking 1/4 mass is placed in mixer, adds pretreated raw material, vitamin C, dimension life
Element E, tryptophan, cobaltous sulfate, carnitine, propyl p-hydroxybenzoate, dibenzylatiooluene, white carbon, curcumin, mixing
20 minutes, standby；
(6) take remaining Chinese medicine extract to be placed in another mixer, add step (5) gained material, mix 20 minutes,
Subpackage, to obtain final product.
Embodiment 2:
A kind of many young granules, are made up of the raw material of following masses number: Chinese medicine extract 950 parts, vitamin C 50.20
Part, vitamin E 20.60 parts, 55 parts of Semen Pisi sativi leaf, fish flour 18 parts, Semen Raphani 27 parts, Rhizoma Polygonati 22.8 parts, tryptophan 18 parts, sulphuric acid
Cobalt 5.5 parts, carnitine 7 parts, propyl p-hydroxybenzoate 4 parts, dibenzylatiooluene 8 parts, white carbon 7 parts, curcumin 5.5
Part.
Described Chinese medicine extract is made up of the raw material of following masses number: 29.5 parts of Radix Dauci Sativae, Fructus Lycii 23 parts.
The preparation method of Chinese medicine extract is:
(1) Fructus Lycii 45 DEG C of water-baths of ether of 10 times of quality are extracted 200 minutes, filter, obtain filtering residue；
(2) distilled water filtering residue being added 20.5 times of quality extracts 4.5 hours under the conditions of 75 DEG C, is filtrated to get Aqueous extracts；
(3) Aqueous extracts is centrifuged under the conditions of 1600r/min, isolated supernatant；
(4) D113 ion exchange resin column on supernatant, upper column flow rate is 1.5BV/h, with 90% ethanol-the third of 3BV
Ketone mixed liquor, the 70% ethanol-acetone mixed liquor of 2BV, the 50% ethanol-acetone mixed liquor of 1BV carries out gradient elution successively, washes
Separation of flow speed is 1.5BV/h, collects gradient eluent；
(5) the 1/3 of gradient eluent decompression and solvent recovery to original volume, it is dried, standby；
(6) Radix Dauci Sativae being pulverized, the extract obtained with upper step merges, and is Chinese medicine extract.
Wherein, in step (4), the volume ratio of supernatant and D113 ion exchange resin column is 2:1, the height of resin column and
Diameter ratio is for 8:1, and in 90% ethanol-acetone mixed liquor, the volume ratio of 90% ethanol and acetone is 4:1, and 70% ethanol-acetone mixes
Closing the volume of 70% ethanol and acetone in liquid is 3:1, and in 50% ethanol-acetone mixed liquor, the volume ratio of 50% ethanol and acetone is
2:1。
A kind of many young granules, its preparation method is:
(1) the Semen Raphani distilled water of 8 times of quality is decocted 60 minutes, filter, obtain filtrate I and filtering residue I；
(2) filtering residue I and fish flour mix homogeneously, standby；
(3) Semen Pisi sativi leaf and Rhizoma Polygonati being joined in filtrate I, add 95% ethanol and make alcohol content be 30%, centrifugal, rotating speed is
850r/min, isolated precipitates；
(4) material that the precipitation that upper step is obtained obtains with (2) step is mixed homogeneously, with the distillation of gross mass 3.5 times
Water washs, and obtains pretreated raw material；
(5) Chinese medicine extract taking 1/4 mass is placed in mixer, adds pretreated raw material, vitamin C, dimension life
Element E, tryptophan, cobaltous sulfate, carnitine, propyl p-hydroxybenzoate, dibenzylatiooluene, white carbon, curcumin, mixing
25 minutes, standby；
(6) take remaining Chinese medicine extract to be placed in another mixer, add step (5) gained material, mix 25 minutes,
Subpackage, to obtain final product.
Embodiment 3:
A kind of many young granules, are made up of the raw material of following masses number: Chinese medicine extract 1000 parts, vitamin C 50.30
Part, vitamin E2 0.70 part, 56 parts of Semen Pisi sativi leaf, fish flour 19 parts, Semen Raphani 27.5 parts, Rhizoma Polygonati 23.0 parts, tryptophan 20 parts, sulphuric acid
Cobalt 6.5 parts, carnitine 8 parts, propyl p-hydroxybenzoate 4.4 parts, dibenzylatiooluene 9 parts, white carbon 8 parts, curcumin 6
Part.
Described Chinese medicine extract is made up of the raw material of following masses number: 30 parts of Radix Dauci Sativae, Fructus Lycii 23.8 parts.
The preparation method of Chinese medicine extract is:
(1) Fructus Lycii 50 DEG C of water-baths of ether of 11 times of quality are extracted 220 minutes, filter, obtain filtering residue；
(2) distilled water filtering residue being added 21 times of quality extracts 5 hours under the conditions of 80 DEG C, is filtrated to get Aqueous extracts；
(3) Aqueous extracts is centrifuged under the conditions of 1700r/min, isolated supernatant；
(4) D113 ion exchange resin column on supernatant, upper column flow rate is 1.6BV/h, with 90% ethanol-the third of 3BV
Ketone mixed liquor, the 70% ethanol-acetone mixed liquor of 2BV, the 50% ethanol-acetone mixed liquor of 1BV carries out gradient elution successively, washes
Separation of flow speed is 1.6BV/h, collects gradient eluent；
(5) the 1/3 of gradient eluent decompression and solvent recovery to original volume, it is dried, standby；
(6) Radix Dauci Sativae being pulverized, the extract obtained with upper step merges, and is Chinese medicine extract.
Wherein, in step (4), the volume ratio of supernatant and D113 ion exchange resin column is 2:1, the height of resin column and
Diameter ratio is for 8:1, and in 90% ethanol-acetone mixed liquor, the volume ratio of 90% ethanol and acetone is 4:1, and 70% ethanol-acetone mixes
Closing the volume of 70% ethanol and acetone in liquid is 3:1, and in 50% ethanol-acetone mixed liquor, the volume ratio of 50% ethanol and acetone is
2:1。
A kind of many young granules, its preparation method is:
(1) the Semen Raphani distilled water of 9 times of quality is decocted 70 minutes, filter, obtain filtrate I and filtering residue I；
(2) filtering residue I and fish flour mix homogeneously, standby；
(3) Semen Pisi sativi leaf and Rhizoma Polygonati being joined in filtrate I, add 95% ethanol and make alcohol content be 30%, centrifugal, rotating speed is
900r/min, isolated precipitates；
(4) material that the precipitation that upper step is obtained obtains with (2) step is mixed homogeneously, with the distilled water of gross mass 4 times
Washing, obtains pretreated raw material；
(5) Chinese medicine extract taking 1/4 mass is placed in mixer, adds pretreated raw material, vitamin C, dimension life
Element E, tryptophan, cobaltous sulfate, carnitine, propyl p-hydroxybenzoate, dibenzylatiooluene, white carbon, curcumin, mixing
30 minutes, standby；
(6) take remaining Chinese medicine extract to be placed in another mixer, add step (5) gained material, mix 30 minutes,
Subpackage, to obtain final product.
Comparative example 1:
Much a kind of young granule, is made up of the raw material of following masses number: Chinese medicine extract 1200 parts, vitamin C 45 parts,
Vitamin E 25 parts, 50 parts of Semen Pisi sativi leaf, fish flour 25 parts, Semen Raphani 20 parts, Rhizoma Polygonati 25 parts, tryptophan 10 parts, cobaltous sulfate 10 parts, meat
Poison 5 parts of alkali, propyl p-hydroxybenzoate 5 parts, dibenzylatiooluene 10 parts, white carbon 5 parts, curcumin 8 parts.
Described Chinese medicine extract is made up of the raw material of following masses number: 25 parts of Radix Dauci Sativae, Fructus Lycii 29 parts.
Remaining is with embodiment 1.
Comparative example 2:
A kind of many young granules, the preparation method of Chinese medicine extract is:
(1) Fructus Lycii 45 DEG C of water-baths of acetone of 10 times of quality are extracted 200 minutes, filter, obtain filtering residue；
(2) distilled water filtering residue being added 20.5 times of quality extracts 4.5 hours under the conditions of 75 DEG C, is filtrated to get Aqueous extracts；
(3) Aqueous extracts is centrifuged under the conditions of 1600r/min, isolated supernatant；
(4) D113 ion exchange resin column on supernatant, upper column flow rate is 1.5BV/h, with 90% ethanol of 3BV, 2BV
70% ethanol, 50% ethanol of 1BV carries out gradient elution successively, and elution flow rate is 1.5V/h, collect gradient eluent；
(5) the 1/3 of gradient eluent decompression and solvent recovery to original volume, it is dried, standby；
(6) Radix Dauci Sativae being pulverized, the extract obtained with upper step merges, and is Chinese medicine extract.
Remaining is with embodiment 2.
Comparative example 3:
A kind of many young granules, are made up of the raw material of following masses number: Chinese medicine extract 1000 parts, vitamin C 50.30
Part, vitamin E 20.70 parts, fish flour 19 parts, Rhizoma Polygonati 23.0 parts, tryptophan 20 parts, cobaltous sulfate 6.5 parts, carnitine 8 parts, to hydroxyl
Yl benzoic acid propyl ester 4.4 parts, dibenzylatiooluene 9 parts, white carbon 8 parts, curcumin 6 parts.
A kind of many young granules, its preparation method is:
(1) Chinese medicine extract taking 1/4 mass is placed in mixer, adds vitamin C, vitamin E, fish flour, Rhizoma Polygonati, color
Propylhomoserin, cobaltous sulfate, carnitine, propyl p-hydroxybenzoate, dibenzylatiooluene, white carbon, curcumin, mix 30 points
Clock, standby；
(2) take remaining Chinese medicine extract to be placed in another mixer, add step (1) gained material, mix 30 minutes,
Subpackage, to obtain final product.
Remaining is with embodiment 3.
1. the present invention impact on sow reproductive performance
Choose parity, body condition close, the in-pig (long white × Yorkshire) 140 being in a good state of health, it is randomly divided into 7
Group, for matched group, embodiment 1-3 group and comparative example 1-3 group, often group 20.
Matched group sow feeds in-pig diet, embodiment 1-3 group and comparative example 1-3 group for 1-89 days pregnant pregnant
It is pregnent and the within 1-89 days, feeds in-pig diet (respectively containing the feedstuff that 10% embodiment 1-3 group and comparative example 1-3 group are prepared)；Pregnant
Be pregnent the 90th to childbirth the same day matched group sow feeding nursing sow diet, embodiment 1-3 group and comparative example 1-3 group feed suckling mother
Pig diet (feedstuff prepared containing 10% embodiment 1-3 group and comparative example 1-3 group respectively), reproductive performance is as shown in table 1.Test number
Statistical analysis is carried out according to using SPSS 13.0 to analyze software.
Litter size=farrowed pig total head number/sow total head number；
Number born alive=produced survival piglet total head number/sow total head number；
Weigth at birth=farrowed pig gross weight/farrowed pig total head number；
Table 1 present invention impact on reproduction performance of gestation sow
As known from Table 1, the how young granule (embodiment 1-3) that the present invention prepares can significantly improve the litter size of sow, product
Live young number and weigth at birth, and effect be substantially better than comparative example 1 (proportioning raw materials is different) and comparative example 2 (Chinese medicine extract
Extraction process is different), comparative example 3 (being not added with Semen Pisi sativi leaf and Semen Raphani in raw material), the especially effect with embodiment 2 optimum,
The curative effect of prepared product is all had an impact by the proportioning of visible raw material, the extraction process of Chinese medicine extract and natural plant composition,
Therefore present invention employs specific proportioning raw materials, the extraction process of Chinese medicine extract and select suitable natural plant composition,
The how young granule prepared can improve sow breeding function.
2. the present invention impact on Small intestine advance activity
Choosing white mice 70, be randomly divided into 7 groups, often group 10,1-6 group gavage respectively is given and embodiment of the present invention 1-
3 and comparative example 1-3 prepare feedstuff 1.5g/kg, the 7th group of gavage normal saline 1.5mL/kg, as blank group.Give continuously
Medicine 3 days, after last administration 1h, gavage is to activated carbon 0.4mL/ only；Put to death animal after 20 minutes, with pylorus as starting point, measure efficient
Distance that property charcoal is pushed into and the total length of small intestinal.Then the propelling rate of activated carbon is calculated, as shown in table 2.Test data is adopted
Analyze software with SPSS 13.0 and carry out statistical analysis.
Propelling rate=the activated carbon of activated carbon distance (cm)/small intestinal total length × 100% in small intestinal
Table 2 present invention impact (x ± s) on mice intestine movement
| Group | Propelling rate |
| Blank group | 0.747±0.053 |
| Embodiment 1 | 0.945±0.042 |
| Embodiment 2 | 0.982±0.047 |
| Embodiment 3 | 0.950±0.069 |
| Comparative example 1 | 0.831±0.085 |
| Comparative example 2 | 0.793±0.052 |
| Comparative example 3 | 0.806±0.060 |
As known from Table 2, the how young granule (embodiment 1-3) that the present invention prepares can significantly improve the Intestinal pushing to mice
Rate, and effect be substantially better than comparative example 1 (proportioning raw materials is different) and comparative example 2 (extraction process of Chinese medicine extract is different),
Comparative example 3 (being not added with Semen Pisi sativi leaf and Semen Raphani in raw material), especially optimum with the effect of embodiment 2, it is seen that the proportioning of raw material,
The curative effect of prepared product is all had an impact by the extraction process of Chinese medicine extract and natural plant composition, therefore present invention employs
Specific proportioning raw materials, the extraction process of Chinese medicine extract and select suitable natural plant composition, prepared how young granules can
To promote intestine movement, the intestines and stomach is had certain opsonic action, have beneficial effect to improving digestive system simultaneously.
Claims (5)
1. more than, a young granule, is characterized by: be made up of the raw material of following masses number: Chinese medicine extract 900-1000 part, dimension
Raw element C 50.10-50.30 part, vitamin E 20.50-20.70 part, carrier.
2. more than, a young granule, is characterized by: be made up of the raw material of following masses number: Chinese medicine extract 900-1000 part, dimension
Raw element C 50.10-50.30 part, vitamin E 20.50-20.70 part, Semen Pisi sativi leaf 54-56 part, fish flour 17-19 part, Semen Raphani
26.5-27.5 part, Rhizoma Polygonati 22.6-23.0 part, tryptophan 15-20 part, cobaltous sulfate 4.5-6.5 part, carnitine 6-8 part, to hydroxyl
Propyl benzoate 3.6-4.4 part, dibenzylatiooluene 7-9 part, white carbon 6-8 part, curcumin 5-6 part.
3. a kind of many young granules as claimed in claim 2, is characterized by:
Chinese medicine extract is made up of the raw material of following masses number: Radix Dauci Sativae 29-30 part, Fructus Lycii 22.4-23.8 part.
4. a kind of many young granules, is characterized by:
The preparation method of Chinese medicine extract is:
(1) Fructus Lycii 40-50 DEG C of water-bath of ether of 9-11 times of quality is extracted 180-220 minute, filter, obtain filtering residue；
(2) filtering residue is added the distilled water of 20-21 times of quality to extract 4-5 hour under the conditions of 70-80 DEG C, be filtrated to get Aqueous extracts；
(3) Aqueous extracts is centrifuged under the conditions of 1500-1700r/min, isolated supernatant；
(4) D113 ion exchange resin column on supernatant, upper column flow rate is 1.4-
1.6BV/h, by the 90% ethanol-acetone mixed liquor of 3BV, the 70% ethanol-acetone mixed liquor of 2BV, 50% second of 1BV
Alcohol-acetone mixture carries out gradient elution successively, and elution flow rate is 1.4-1.6BV/h, collects gradient eluent；
(5) the 1/3 of gradient eluent decompression and solvent recovery to original volume, it is dried, standby；
(6) Radix Dauci Sativae being pulverized, the extract obtained with upper step merges, and is Chinese medicine extract；
Wherein, in step (4), the volume ratio of supernatant and D113 ion exchange resin column is 2:1, the height of resin column and diameter
Ratio is 8:1, and in 90% ethanol-acetone mixed liquor, the volume ratio of 90% ethanol and acetone is 4:1,70% ethanol-acetone mixed liquor
In the volume of 70% ethanol and acetone be 3:1, in 50% ethanol-acetone mixed liquor, the volume ratio of 50% ethanol and acetone is 2:1.
5. a kind of many young granules as claimed in claim 2, is characterized by:
Its preparation method is:
(1) the Semen Raphani distilled water of 7-9 times of quality is decocted 50-70 minute, filter, obtain filtrate I and filtering residue I；
(2) filtering residue I and fish flour mix homogeneously, standby；
(3) Semen Pisi sativi leaf and Rhizoma Polygonati being joined in filtrate I, add 95% ethanol and make alcohol content be 30%, centrifugal, rotating speed is 800-
900r/min, isolated precipitates；
(4) material that the precipitation that upper step is obtained obtains with (2) step is mixed homogeneously, and washes with the distillation of gross mass 3-4 times
Wash, obtain pretreated raw material；
(5) Chinese medicine extract taking 1/4 mass is placed in mixer, add pretreated raw material, vitamin C, vitamin E,
Tryptophan, cobaltous sulfate, carnitine, propyl p-hydroxybenzoate, dibenzylatiooluene, white carbon, curcumin, mix 20-
30 minutes, standby；
(6) take remaining Chinese medicine extract to be placed in another mixer, add step (5) gained material, mix 20-30 minute,
Subpackage, to obtain final product.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1947544A (en) * | 2006-09-18 | 2007-04-18 | 阜新红日牧业有限公司 | Forage for sow with functions of promoting sexual maturity fetus-care and health-care |
| CN104824454A (en) * | 2015-05-18 | 2015-08-12 | 新希望六和饲料股份有限公司 | Sow formula feed and preparation method thereof |
| CN105211502A (en) * | 2015-09-18 | 2016-01-06 | 北京科慧通智慧科技有限公司 | Green feed additive |
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2016
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1947544A (en) * | 2006-09-18 | 2007-04-18 | 阜新红日牧业有限公司 | Forage for sow with functions of promoting sexual maturity fetus-care and health-care |
| CN104824454A (en) * | 2015-05-18 | 2015-08-12 | 新希望六和饲料股份有限公司 | Sow formula feed and preparation method thereof |
| CN105211502A (en) * | 2015-09-18 | 2016-01-06 | 北京科慧通智慧科技有限公司 | Green feed additive |
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Application publication date: 20161214 |