CN106177463A - A kind of Chinese medicine treating amenorrhea caused by antipsychotic drug - Google Patents
A kind of Chinese medicine treating amenorrhea caused by antipsychotic drug Download PDFInfo
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- CN106177463A CN106177463A CN201610718264.XA CN201610718264A CN106177463A CN 106177463 A CN106177463 A CN 106177463A CN 201610718264 A CN201610718264 A CN 201610718264A CN 106177463 A CN106177463 A CN 106177463A
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- 239000003814 drug Substances 0.000 title claims abstract description 63
- 229940079593 drug Drugs 0.000 title claims abstract description 34
- 201000000736 Amenorrhea Diseases 0.000 title claims abstract description 33
- 206010001928 Amenorrhoea Diseases 0.000 title claims abstract description 33
- 231100000540 amenorrhea Toxicity 0.000 title claims abstract description 33
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Classifications
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Abstract
The invention belongs to the field of Chinese medicines, disclose a kind of Chinese medicine composition treating the particularly deficiency of qi and blood type amenorrhea of amenorrhea caused by antipsychotic drug.The present invention according to the etiology and pathogenesis of primary disease, the selected crude drug such as Caulis et Folium Fici beecheyanae, Radix Polygalae fallacis, clay ox party seven, Streptopus simplex D. Don, Gui Mugen, Flos Cymbidii Ensifolii, Radix Caraganae intermediae, Caulis Spatholobi, Herba hemipharagmatis heterophylli, Fructus Leonuri, Mao Lian, mountain hair moss, spun gold brush, Radix Glycyrrhizae.Prescription of the present invention is concise and rigorous, all linked with one another with pathogenesis, and full side has effect of benefiting vital QI and blood, invigorating the spleen and regulating the stomach, nourishing blood for regulating menstruation, tranquillizing and allaying excitement.Chinese medicine of the present invention has no side effect, it is applicable to different amenorrhea caused by anti-semen antibody, does not affect the absorption of anti-semen antibody, not only the anti-semen antibody taken with patient is without antagonism, also can assist play calm the nerves, calm effect, improve the compliance of patient's Taking Antipsychotics.Overall clinical efficacy rate reaches 97.30%, and clinic is promoted.
Description
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to one and treat the especially deficiency of qi and blood of amenorrhea caused by antipsychotic drug
The Chinese medicine of type amenorrhea.
Background technology
Anti-semen antibody is a kind of effective ways for the treatment of cyclothymic, but clinical application for many years shows, takes for a long time
Can be to human body with anti-semen antibody such as chlorpromazine, perphenazine, fluphenazine, sulpiride, penfluridol, risperidone, olanzapine etc.
Hormonal system produce the biggest interference, for female patient, amenorrhea be the most serious and insoluble drug induccd not
One of good reaction.
Doctor trained in Western medicine is thought, antipsychotic drug is formed by the dopamine receptor in retardance human body so that the nodule in human body
The Major Systems such as funnel produce abnormal, greatly the secretion of the prolactin antagonist in stimulation human body, and dopamine receptor is by suppression human body
Interior prolactin antagonist release and raising, can cause women to do sth. in advance amenorrhea, affects female body health and happy family life.This problem is
Through becoming one of subject matter of puzzlement women psychiatric treatment for many years.
Traditional Chinese medical science viewpoint is thought: apply psychosis class medicine easily QI of the spleen and stomach to be caused damage in the long-time course of disease,
The deficiency in being manifested initially by source, the mistake that punching is appointed is foster, and depletion of blood, so that row, ultimately results in amenorrhea.The store blood of poison of drug heresy invasion and attack liver
Effect, runs mechanism of qi the most smooth, ultimately results in amenorrhea.What the present invention mainly studied is the deficiency of qi and blood caused by antipsychotic drug
The treatment of type amenorrhea.Its main clinical manifestation is: prolong after menstrual cycle, and on the low side through amount, color is light, matter is dilute, then amenorrhea.Complexion is not
Honor, has a dizzy spell, shortness of breath and palpitation, spiritlessness and weakness.Light red tongue limit has tooth to print, thin fur, thready pulse without strength.
In prior art, amenorrhea most efficient method caused by treatment antipsychotic drug is drug withdrawal, and psychotic
Need Long-term taking medicine symptom management, the appearance of menolipsis phenomenon, bigger negative effect can be brought to patient, be allowed to produce and reduce or stop
By the idea of psychosis, the generation feared state of mind of taking medicine during to psychosis after treatment, this is also to affect women psychosis
The one of the main reasons of patient's drug compliance.If using western medicine amenorrhea, easily disturb the treatment of mental sickness, Er Qieyou
Certain side effect.Using the Chinese patent medicines such as ease pill, Herba Leonuri paste, ANLE PIAN, WUJI BAIFENG WAN to treat, effect is paid no attention to mostly
Think, there is the shortcomings such as high, the compliance difference of recurrent.
Summary of the invention
It is an object of the invention to, it is provided that one treats the especially deficiency of qi and blood type amenorrhea of amenorrhea caused by antipsychotic drug
Chinese medicine.
Technical program of the present invention lies in, a kind of Chinese medicine treating amenorrhea caused by antipsychotic drug is joined by following weight parts
The crude drug composition of ratio: Caulis et Folium Fici beecheyanae 50-80, Radix Polygalae fallacis 30-50, clay ox party seven 15-30, Streptopus simplex D. Don 10-20, Gui Mugen
15-30, Flos Cymbidii Ensifolii 10-15, Radix Caraganae intermediae 15-25, Caulis Spatholobi 9-15, Herba hemipharagmatis heterophylli 15-50, Fructus Leonuri 5-10, hair connect 10-15,
Mountain hair moss 20-25, spun gold brush 9-12, Radix Glycyrrhizae 3-8.
Preferably, technical program of the present invention lies in, a kind of Chinese medicine of amenorrhea caused by antipsychotic drug for the treatment of is by following
The crude drug composition of weight: Caulis et Folium Fici beecheyanae 60, Radix Polygalae fallacis 40, clay ox party 7 20, Streptopus simplex D. Don 20, osmanthus wood root 20, build
Cymbidium ensifolium (L.) Sw. 10, Radix Caraganae intermediae 20, Caulis Spatholobi 10, Herba hemipharagmatis heterophylli 40, Fructus Leonuri 5, hair connect 10, mountain hair moss 20, spun gold brush 10, Radix Glycyrrhizae 5.
Contained by the present invention, the pharmacological property of each crude drug is analyzed as follows.
Caulis et Folium Fici beecheyanae: stem, leaf for moraceae plants Fructus Fici Beecheyanae are used as medicine.Nature and flavor: sweet light, temperature.Enter lung, spleen, kidney three warp.Can invigorating middle warmer
QI invigorating, invigorating the spleen for eliminating dampness, bone and muscle strengthening, detumescence, promoting blood circulation and detoxication.Dispelling the wind and dampness pathogens arthralgia, the middle deficiency of vital energy is weak, and QI and blood is on the decline, and extremity are aching and limp,
Stiffness of the muscle and joint, traumatic injury, amenorrhea, galactostasis.
Radix Polygalae fallacis: the root for Polygalaceae polygala Radix Polygalae fallacis is used as medicine.Nature and flavor: hardship sweet, micro-are flat.Can mend
Replenishing QI and blood, invigorating spleen to remove dampness, promoting blood flow to regulate menstruation.Empty for body after being ill, soreness of waist and knee joint, traumatic injury, icterohepatitis, oedema due to nephritis,
Uterine prolapse, leucorrhea, menoxenia.
Clay ox party seven: for the root of apocynaceae plant Herba Lycianthis Biflorae rattan.Nature and flavor: micro-sweet；Micro-hardship；Cool in nature.Can spleen invigorating qi-restoratives；Heat clearing away
Removing toxic substances.Cure mainly dyspepsia；Blood deficiency breast is few；Aphtha of the mouth and tongue；Toothache.
Streptopus simplex D. Don: the root for Liliaceae Streptopus simplex D. Don is used as medicine.Nature and flavor: sweet, light, cold.Can clearing away lung-heat to relieve cough, invigorating the spleen and regulating the stomach.Cure mainly
Cough due to lung-heat, incoordination between the spleen and stomach, have palpitation, breathe hard, bones and muscles pain.
Gui Mugen: the root for moraceae plants osmanthus wood is used as medicine.Nature and flavor: pungent；Slightly warm in nature.Return stomach warp.Can invigorating the spleen and regulating the stomach；Dispel the wind work
Blood.Cure mainly gastral cavilty not relax；Inappetence；Rheumatic arthralgia；Traumatic injury.
Flos Cymbidii Ensifolii: the flower for orchid sword-leaved cymbidium is used as medicine.Acrid in the mouth is flat.Enter the heart, spleen, lung three warp.Can regulate the flow of vital energy, alleviating distention in middle-JIAO, bright
Mesh.Control chronic cough, uncomfortable in chest, diarrhoea, optic atrophy." detailed outline is picked up any lost article from the road ": " wish Flos Cymbidii Ensifolii removes place gas, resolving depression.Candied Dracocephalum moldabium flower point tea
Drink, QI and blood regulating, alleviating distention in middle-JIAO relieving alcoholic intoxication.Hemerocallis citrina Baroni person's name honey is blue, can be with antidiarrheal.Darkish complexion person's name Chinese cymbidium, controls optic atrohic blindness and imitates most ".
Radix Caraganae intermediae: for the root of leguminous plant Caragana intermedia.Taste is micro-pungent, warm in nature.Can nourishing YIN and benefiting blood.Control hypertension, dizziness,
Have palpitation, breathe hard, tired.
Caulis Spatholobi: for the dry rattan of leguminous plant spatholobus suberectus (Caulis Sargentodoxae, Radix seu Caulis Verntilaginis Leiocarpae, SANYE Caulis Spatholobi, nine layers of wind).Property
Taste: bitter, sweet, temperature.Return liver, kidney channel.Can enrich blood, invigorate blood circulation, dredging collateral.For menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatism numbness
Bitterly.
Herba hemipharagmatis heterophylli: for all herbal medicine of Scrophulariaceae diversifolious hemiphragma herb platymiscium diversifolious hemiphragma herb.Nature and flavor: light are flat.Can promoting blood flow to regulate menstruation,
Relaxing muscles and tendons and activating QI and blood in the collateral, expelling wind and removing dampness.For amenorrhea, menoxenia, pulmonary tuberculosis, tonsillitis, traumatic injury, lumbago due to pathogenic wind-dampness；External is controlled
Eczema, skin infection, stomatitis.
Fructus Leonuri: for the dry mature fruit of labiate Herba Leonuri, the present invention selects Fructus Leonuri (parched).Nature and flavor: pungent,
Hardship, is slightly cold.GUIXIN bag, Liver Channel.Can promoting blood flow to regulate menstruation, liver heat removing and eyesight improving.For menoxenia, amenorrhea, dysmenorrhea, cataract, dizziness
Distending pain.
Mao Lian: for all herbal medicine of side, Ranunculaceae Pheasant's-Eye Sichuan gold small cup.Nature and flavor: bitter are cool.Can heat clearing away dry
Wet, calm.For carbuncle sore tumefacting virus, conjunctival congestion and swelling pain, vomiting dysentery, cardiopalmus sleeplessness, epilepsy.
Mountain hair moss: for all herbal medicine of hair Rhodobryum plant mountain, moss Dicranaceae mountain hair moss.Nature and flavor: sweet, light are flat.Can
Replenishing YIN and removing heat, nourishing blood to tranquillize the mind.For deficiency of YIN hectic fever, neurasthenia, demented, bones and muscles pain.
Spun gold brush: for the thallus of Parmeliaceae plant spun gold brush.Nature and flavor: bitter；Flat.GUIXIN, Liver Channel.Can calm the nerves；Suppressing the hyperactive liver；Live
Blood；Sore.Cure mainly insomnia；Epilepsy；Dizziness；Traumatic injury；Burn due to hot liquid or fire.
Radix Glycyrrhizae: this product is the dry root of glycyrrhizic legume.Nature and flavor: sweet are flat.GUIXIN, lung, spleen, stomach warp.Can spleen reinforcing benefit
Gas, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, expectorant of coughing
Many, gastral cavity abdomen, extremity contraction urgency pain, carbuncle sore tumefacting virus, cushion toxicity, strong.
The method of preparation and use of the present invention is: decocted twice by each crude drug decocting method routinely, merging filtrate and get final product.
When taking, monthly menstrual cycle is taken on the 7th day, every day 1 dose, and decocting takes concoction point twice decoction being taken warmly, each 200ml sooner or later, serve on
It within 14 days, it is a course for the treatment of.
Inventor thinks: apply psychosis class medicine that QI of the spleen and stomach easily causes damage, taste when long in the course of disease
Deficient, change source not enough, store blood effect of poison of drug heresy invasion and attack liver, cause deficiency of qi and blood, punching to appoint and do not fill, the sea of blood is hollow, and depletion of blood can
Under, therefore infrequent menstruation is gradually not all right to closing down；Blood deficiency can not go up flourish in face, then shallow complexion；The deficiency of vital energy is depressed, therefore fatigue in both spirit and physical strength；Brain
Marrow loses supports, therefore dizziness and blurred vision；Blood failing to tonify the heart, therefore shortness of breath and palpitation；Light red tongue, thin fur, thready pulse without strength, be levying of deficiency of qi and blood.
So, inventor " benefiting vital QI and blood, invigorating the spleen and regulating the stomach, supports because using when taking amenorrhea that psychosis causes in treatment
Blood regulating menstruation, tranquillizing and allaying excitement " principle treat, all medicines share because taking the amenorrhea particularly deficiency of qi and blood that psychosis causes
Type amenorrhea treatment curative effect certainly, and has no side effect, and the most psychotolytic treatment, and can improve clothes for patients with anti-
The compliance of antipsychotic drugs.Wherein Caulis et Folium Fici beecheyanae, Radix Polygalae fallacis, clay ox party seven, Streptopus simplex D. Don, Gui Mugen, Flos Cymbidii Ensifolii compatibility can
Play effect of benefiting vital QI and blood, invigorating the spleen and regulating the stomach；Radix Caraganae intermediae, Caulis Spatholobi, Herba hemipharagmatis heterophylli, Fructus Leonuri compatibility can play blood-supplementing blood-nourishing,
Effect of promoting blood circulation to restore menstrual flow；Mao Lian, mountain hair moss, spun gold brush can heat clearing away be calm, nourishing blood to tranquillize the mind；Add Radix Glycyrrhizae invigorating the spleen and replenishing QI, only eliminate the phlegm
Cough, heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription.
The beneficial effects of the present invention is: 1, each medicine property of medicine is all linked with one another, jointly play benefiting vital QI and blood, invigorating the spleen and regulating the stomach,
Nourishing blood for regulating menstruation, effect of tranquillizing and allaying excitement.2, Chinese medicine of the present invention has no side effect, it is adaptable to different amenorrheas caused by anti-semen antibody,
Do not affect the absorption of anti-semen antibody, not only the anti-semen antibody taken with patient be without antagonism, also can assist play calm the nerves,
Calm effect, improves the compliance of patient's Taking Antipsychotics.3, Chinese medicine of the present invention preparation is simple, and taking convenience faces
Bed is remarkably productive.
Detailed description of the invention
Embodiment 1: a kind of Chinese medicine (unit: gram) treating amenorrhea caused by antipsychotic drug: Caulis et Folium Fici beecheyanae 50, Hemerocallis citrina Baroni pouring
Lotus 30, clay ox party 7 15, Streptopus simplex D. Don 10, osmanthus wood root 15, Flos Cymbidii Ensifolii 10, Radix Caraganae intermediae 15, Caulis Spatholobi 9, Herba hemipharagmatis heterophylli 15, Fructus Leonuri
5, hair connect 10, mountain hair moss 20, spun gold brush 9, Radix Glycyrrhizae 3.Each crude drug decocting method routinely is decocted twice, merging filtrate and get final product.
When taking, monthly menstrual cycle is taken on the 7th day, every day 1 dose, and decocting takes concoction point twice decoction being taken warmly, each 200ml sooner or later, serve on
It within 14 days, it is a course for the treatment of.
Embodiment 2: a kind of Chinese medicine (unit: gram) treating amenorrhea caused by antipsychotic drug: Caulis et Folium Fici beecheyanae 60, Hemerocallis citrina Baroni pouring
Lotus 40, clay ox party 7 20, Streptopus simplex D. Don 20, osmanthus wood root 20, Flos Cymbidii Ensifolii 10, Radix Caraganae intermediae 20, Caulis Spatholobi 10, Herba hemipharagmatis heterophylli 40, motherwort
Son 5, hair connect 10, mountain hair moss 20, spun gold brush 10, Radix Glycyrrhizae 5.Being decocted twice by each crude drug decocting method routinely, merging filtrate is i.e.
?.When taking, monthly menstrual cycle is taken on the 7th day, every day 1 dose, and decocting takes concoction point twice decoction being taken warmly sooner or later, each 200ml, even
Take 14 days is a course for the treatment of.
Embodiment 3: a kind of Chinese medicine (unit: gram) treating amenorrhea caused by antipsychotic drug: Caulis et Folium Fici beecheyanae 80, Hemerocallis citrina Baroni pouring
Lotus 50, clay ox party 7 30, Streptopus simplex D. Don 20, osmanthus wood root 30, Flos Cymbidii Ensifolii 15, Radix Caraganae intermediae 25, Caulis Spatholobi 15, Herba hemipharagmatis heterophylli 50, motherwort
Son 10, hair connect 15, mountain hair moss 25, spun gold brush 12, Radix Glycyrrhizae 8.Being decocted twice by each crude drug decocting method routinely, merging filtrate is i.e.
?.When taking, monthly menstrual cycle is taken on the 7th day, every day 1 dose, and decocting takes concoction point twice decoction being taken warmly sooner or later, each 200ml, even
Take 14 days is a course for the treatment of.
Below, in conjunction with clinical data, beneficial effects of the present invention is described further.
L data and method
1.1 case basic conditions
Amenorrhea caused by psychosis is taken at my Out-patient Department and hospitalization selected from 74 example in June, 2010 in December, 2013
Female psychotic.Enter group standard: (1) meets " Chinese Spirit Obstacles classification and diagnostic criteria " the 3rd edition (CCMD-3) essence
God's Disease Diagnosis Standard.(2) without menolipsis phenomenon before non-Taking Antipsychotics, the age between 18-4l year, amenorrhea
35 months.(3) gestation and other physical disease are got rid of.Selected 18 20 years old 6 example, 25 28 years old 28 example, 31 34 years old 25 example,
37 41 years old 15 examples；Unmarried 25 example, married 49 examples；More than 3 months person 46 examples of the course of disease, more than 4 months person 22 examples, 5 months 6
Example；Take sulpiride 0.6 0.8g/d22 example, clozapine 75 400mg/d14 example, chlorpromazine 200-400mg/d14 example, put forth energy be
Quiet 6 24mg/d6 examples, risperidone 2-5mg/d18 example.It is randomly divided into treatment group 37 example and matched group 37 example, two groups of physical data
Comparing difference not statistically significant (P > 0.05), has comparability.
1.2 differentiation of symptoms and signs for classification of syndrome
Chinese medical discrimination all cases all meets deficiency of qi and blood type CM syndrome differentiation criterion, and clinical symptoms is that menstruation more than 3 months is the most damp, menstruation
Close down.Complexion is the most flourish, has a dizzy spell, shortness of breath and palpitation, spiritlessness and weakness.Light red tongue limit has tooth to print, thin fur, thready pulse without strength.
2 Therapeutic Method and result
2.1 Therapeutic Method
Treatment group: a kind of Chinese medicine (unit: gram) treating amenorrhea caused by antipsychotic drug: Caulis et Folium Fici beecheyanae 60, Radix Polygalae fallacis 40,
Clay ox party 7 20, Streptopus simplex D. Don 20, osmanthus wood root 20, Flos Cymbidii Ensifolii 10, Radix Caraganae intermediae 20, Caulis Spatholobi 10, Herba hemipharagmatis heterophylli 40, Fructus Leonuri 5, hair
Company 10, mountain hair moss 20, spun gold brush 10, Radix Glycyrrhizae 5.Each crude drug decocting method routinely is decocted twice, merging filtrate and get final product.Take
Time, monthly menstrual cycle is taken on the 7th day, every day 1 dose, and decocting takes concoction point twice decoction being taken warmly, each 200ml sooner or later, serve on 14 days
It it is a course for the treatment of.It serve on three courses for the treatment of.
Matched group: WUJI BAIFENG WAN (traditional Chinese medicines quasi-word Z20055050, big honeyed pills every ball weight 9g), 1 ball, one day 2 times.
The moon starts to take for premenstrual 7 days, disables during to menstrual onset, continues to take to menstrual onset next time, serve on 3 months after menstrual period.
2.2 criterion of therapeutical effect
Reference " Chinese medical disease Standardization of diagnosis and curative effect " (State Administration of Traditional Chinese Medicine, publishing house of Nanjing University, 1994) draft:
Cure: menstrual onset, continuous more than 3 times menorrheas；
Take a turn for the better: menstruation recovery is risen.But menstrual cycle is the most normal；
Do not heal: menstruation is risen not yet.
3 results
| Group | Cure | Take a turn for the better | Do not heal | Total effective rate |
| Treatment group (37 example) | 28(75.68%) | 8(21.62%) | 1(2.70%) | 97.30% |
| Matched group (37 example) | 17(45.95%) | 7(18.92%) | 13(35.14%) | 64.86% |
Two groups, than effect, treatment group total effective rate 97.30%, are significantly higher than matched group 64.86%, have clinical meaning.Treatment group patient
During taking Chinese medicine of the present invention, do not find any untoward reaction.
Claims (2)
1. the Chinese medicine treating amenorrhea caused by antipsychotic drug, it is characterised in that described amenorrhea is that deficiency of qi and blood type closes
Warp, described Chinese medicine is made up of the crude drug of following weight parts proportioning: Caulis et Folium Fici beecheyanae 50-80, Radix Polygalae fallacis 30-50, clay ox party
Seven 15-30, Streptopus simplex D. Don 10-20, osmanthus wood root 15-30, Flos Cymbidii Ensifolii 10-15, Radix Caraganae intermediae 15-25, Caulis Spatholobi 9-15, Herba hemipharagmatis heterophylli
15-50, Fructus Leonuri 5-10, hair connect 10-15, mountain hair moss 20-25, spun gold brush 9-12, Radix Glycyrrhizae 3-8.
A kind of Chinese medicine treating amenorrhea caused by antipsychotic drug, it is characterised in that by following heavy
The crude drug composition of amount part proportioning: Caulis et Folium Fici beecheyanae 60, Radix Polygalae fallacis 40, clay ox party 7 20, Streptopus simplex D. Don 20, osmanthus wood root 20, sword-leaved cymbidium
Spend 10, Radix Caraganae intermediae 20, Caulis Spatholobi 10, Herba hemipharagmatis heterophylli 40, Fructus Leonuri 5, hair connect 10, mountain hair moss 20, spun gold brush 10, Radix Glycyrrhizae 5.
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102008621A (en) * | 2010-12-09 | 2011-04-13 | 张月英 | Traditional Chinese medicine pill for curing amenorrhea resulted from psychotropic drugs and preparation method thereof |
| CN103830422A (en) * | 2014-02-16 | 2014-06-04 | 马芳 | Traditional Chinese medicine for treating amenorrhea |
| CN104740319A (en) * | 2015-03-31 | 2015-07-01 | 惠志强 | Traditional Chinese medicine preparation for preventing side reactions caused by antipsychotics |
| CN104758825A (en) * | 2015-03-26 | 2015-07-08 | 柳晖 | Traditional Chinese medicine composition for treating amenorrhea |
-
2016
- 2016-08-25 CN CN201610718264.XA patent/CN106177463A/en not_active Withdrawn
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102008621A (en) * | 2010-12-09 | 2011-04-13 | 张月英 | Traditional Chinese medicine pill for curing amenorrhea resulted from psychotropic drugs and preparation method thereof |
| CN103830422A (en) * | 2014-02-16 | 2014-06-04 | 马芳 | Traditional Chinese medicine for treating amenorrhea |
| CN104758825A (en) * | 2015-03-26 | 2015-07-08 | 柳晖 | Traditional Chinese medicine composition for treating amenorrhea |
| CN104740319A (en) * | 2015-03-31 | 2015-07-01 | 惠志强 | Traditional Chinese medicine preparation for preventing side reactions caused by antipsychotics |
Non-Patent Citations (1)
| Title |
|---|
| 施慧: "《施慧文集 医学卷》", 30 June 2015, 中国医科科技出版社 * |
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