CN106177283A - Treatment chronic bronchitis, the Yao medicinal composition of bronchial asthma - Google Patents

Treatment chronic bronchitis, the Yao medicinal composition of bronchial asthma Download PDF

Info

Publication number
CN106177283A
CN106177283A CN201610741757.5A CN201610741757A CN106177283A CN 106177283 A CN106177283 A CN 106177283A CN 201610741757 A CN201610741757 A CN 201610741757A CN 106177283 A CN106177283 A CN 106177283A
Authority
CN
China
Prior art keywords
parts
radix
extractum
medicinal composition
chronic bronchitis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610741757.5A
Other languages
Chinese (zh)
Inventor
莫单丹
唐炳兰
周小雷
王硕
龚小妹
候小莉
欧春丽
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guangxi Botanical Garden of Medicinal Plants
Original Assignee
Guangxi Botanical Garden of Medicinal Plants
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guangxi Botanical Garden of Medicinal Plants filed Critical Guangxi Botanical Garden of Medicinal Plants
Priority to CN201610741757.5A priority Critical patent/CN106177283A/en
Publication of CN106177283A publication Critical patent/CN106177283A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • A61K36/03—Phaeophycota or phaeophyta (brown algae), e.g. Fucus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13—Coniferophyta (gymnosperms)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488—Pueraria (kudzu)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/69—Polygalaceae (Milkwort family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention discloses a kind of Yao medicinal composition treating chronic bronchitis, bronchial asthma, including the raw material of following parts by weight: calabash bores 10 30 parts, Radix Puerariae 36 parts, Folium Eucommiae 35 parts, Caulis Gneti 35 parts, Radix Cudraniae 35 parts, Radix Polygalae fallacis 35 parts, Thallus Laminariae (Thallus Eckloniae) 35 parts, eucalyptus leaves 35 parts, Herba speranskiae tuberculatae 12 parts, fevervine 12 parts and Radix Salviae Miltiorrhizae 12 parts.The present invention have removing toxic substances, sore-throat relieving, warming lung for dispelling cold, cough-relieving, relieving asthma reduce phlegm, effect of benefiting QI and nourishing blood, spleen-benefiting mind-tranquilizing, it is a kind of good medicine treating chronic bronchitis, bronchial asthma, curative effect is obvious, energy treating both the principal and secondary aspects of a disease, have no adverse reaction and toxic and side effects, the recurrence after healing can be avoided, raw material resources easily obtain.

Description

Treatment chronic bronchitis, the Yao medicinal composition of bronchial asthma
Technical field
The present invention relates to precious jade medicine formulation art.It is more particularly related to one treats chronic bronchitis, a gas The Yao medicinal composition of pipe asthma.
Background technology
Chronic bronchitis is chronic non-specific by the trachea-bronchial epithelial cell mucosa caused by Different types of etiopathogenises and surrounding tissue thereof Property inflammation.Suffer from cold, smoking and flu often make primary disease induction or increase the weight of.Mainly show as chronic cough, expectoration, repeatedly feel Dye, or with panting.The average prevalence of primary disease China is 3.82%, along with the increase sickness rate at age also increases.The north, mountain District, plateau, cold district and factories and miness, rural area sickness rate height.Obstructive emphysema and chronic pulmonary heart disease can be developed into.
At present, the most typically use oral antibiotic and expectorant of relievining asthma, intravenous applications antibiotic, such as penicillin, ring Third norfloxacin etc.；There is side effect and greatly, easily form drug resistance in said medicine, therapeutic effect is poor, the deficiency at the bottom of cure rate；Cause This research is a kind of evident in efficacy, and the Chinese medicine composition of the treatment chronic bronchitis that side effect is little is the most necessary.
Bronchial asthma is the respiratory tract participated in by multiple inflammatory cells such as eosinophilic granulocyte, mastocyte and T cell Chronic inflammatory reacts, and this inflammatory reaction makes susceptible that various stimulating factors are had respiratory tract high response, and causes not With the extensive Reversible airway obstruction symptom of degree, usually merge respiratory tract bacterial infection simultaneously.Prop up for finding new treatment The medicine of san bronchial asthma the most never stops.
Summary of the invention
It is an object of the invention to solve at least the above, and the advantage that at least will be described later is provided.
It is a still further object of the present invention to provide a kind of Yao medicinal composition treating chronic bronchitis, bronchial asthma. The Yao medicinal composition of the present invention and preparation have removing toxic substances, sore-throat relieving, warming lung for dispelling cold, cough-relieving, relieving asthma reduce phlegm, benefiting QI and nourishing blood, spleen invigorating peace Effect of god, is a kind of good medicine treating chronic bronchitis, bronchial asthma, and curative effect is obvious, can treating both the principal and secondary aspects of a disease, without bad instead Should and toxic and side effects, the recurrence after healing can be avoided, raw material resources easily obtain.
In order to realize according to object of the present invention and further advantage, it is provided that one is treated chronic bronchitis, propped up The Yao medicinal composition of san bronchial asthma, including the raw material of following parts by weight: calabash bores 10-30 part, Radix Puerariae 3-6 part, Folium Eucommiae 3-5 Part, Caulis Gneti 3-5 part, Radix Cudraniae 3-5 part, Radix Polygalae fallacis 3-5 part, Thallus Laminariae (Thallus Eckloniae) 3-5 part, eucalyptus leaves 3-5 part, Herba speranskiae tuberculatae 1-2 part, Fevervine 1-2 part and Radix Salviae Miltiorrhizae 1-2 part.
Preferably, including the raw material of following parts by weight: calabash is bored 15-25 part, Radix Puerariae 4 parts, Folium Eucommiae 4 parts, buys fiber crops 4 parts of rattan, Radix Cudraniae 4 parts, Radix Polygalae fallacis 4 parts, Thallus Laminariae (Thallus Eckloniae) 4 parts, eucalyptus leaves 4 parts, Herba speranskiae tuberculatae 1 part, fevervine 1 part and Radix Salviae Miltiorrhizae 1 part.
Based on technique scheme, present invention also offers the preparation method of a kind of Yao medicinal composition, count by weight, Comprise the following steps:
Step one, 3-6 part powder of Radix Puerariae is broken into the fine powder of more than 100 mesh, standby；
Step 2,10-30 part calabash is bored boiling water extraction 2 times, each 2 hours, merges twice extraction filtrate, reduce pressure dense Contract to obtain the first extractum that relative density is 1.09；
Step 3, by 3-5 part Folium Eucommiae, 3-5 part Caulis Gneti, 3-5 part Radix Cudraniae, 3-5 part Radix Polygalae fallacis, 3-5 part elder brother Cloth and the mixing of 3-5 part eucalyptus leaves, add water, and intense fire decocts 1 as a child slow fire boiling 2 hours, is obtained by the filtrate reduced in volume of filtration Relative density is second extractum of 1.25；
Step 4, by 1-2 part Herba speranskiae tuberculatae, 1-2 part fevervine and 1-2 part Radix Salviae Miltiorrhizae mix, add water, intense fire decoct 0.5 hour Wait slow fire boiling 2 hours, the filtrate reduced in volume of filtration is obtained the 3rd extractum that relative density is 1.2；
Step 5, by the first extractum, the second extractum and the 3rd extractum mixing and with in step one powder of Radix Puerariae mix, i.e. Yao medicinal composition described in.
Based on technique scheme, present invention also offers a kind of pharmaceutical preparation treating chronic bronchitis, by above-mentioned Yao medicinal composition and pharmaceutically acceptable adjuvant composition.
Based on technique scheme, present invention also offers a kind of pharmaceutical preparation treating bronchial asthma, by above-mentioned precious jade Drug composition and pharmaceutically acceptable adjuvant composition.
Using method: oral: tablet: one time 1～2, every day 1～2 times；Capsule: one time 1～2, every day 1～2 Secondary；Granule: one time 1～2 bags (10g/ bag), every day 1～2 times；Oral liquid: one time 30～60ml, every day 1～2 times.Or abide by doctor Advise.
Points for attention: be not taken by pregnant women, avoid pungent food during taking medicine cold and cool food, preventing cold.
Effect duration: 2-3.
The present invention at least includes following beneficial effect: ancient prescription traditional Chinese medical science personage think " lung is not hindered and is not coughed, and spleen does not hinder not chronic cough, Kidney do not hinder do not breathe heavily ", owing to exopathogen invades lung, cause cough, dyspnea with rapid and short breath, cause body opposing exopathogen ability to reduce, thus cause diseases caused by exogenous pathogenic factor The heresy invasion and attack of six climate exopathogens cause the recurrent exerbation of chronic tracheitis.The Yao medicinal composition of the present invention and preparation have disinfecting detoxifying, Tonifying the lung gas, sore-throat relieving, cough-relieving, relieving asthma reduce phlegm, blood circulation promoting and blood stasis dispelling, spleen-benefiting mind-tranquilizing, the effect of the chest stuffiness relieving of regulating the flow of vital energy, it is possible to strengthening vital QI to eliminate pathogenic factors, improve Immunity, is a kind of good medicine treating chronic bronchitis, bronchial asthma, and curative effect is obvious, and cure rate is high, energy treating both the principal and secondary aspects of a disease, Having no adverse reaction and toxic and side effects, the recurrence after healing can be avoided, raw material resources easily obtain.
Part is embodied by the further advantage of the present invention, target and feature by description below, and part also will be by this Invention research and practice and be understood by the person skilled in the art.
Detailed description of the invention
The invention discloses a kind of Yao medicinal composition treating chronic bronchitis, bronchial asthma.People in the art Member can use for reference present disclosure, is suitably modified technological parameter and realizes.Special needs to be pointed out is, all similar replacements and change Apparent to those skilled in the art, they are considered as being included in the present invention.The method of the present invention and application Being described by preferred embodiment, related personnel substantially can be right in without departing from present invention, spirit and scope Method described herein and application are modified or suitably change and combine realizing and applying the technology of the present invention.
Embodiment 1
A kind of Yao medicinal composition treating chronic bronchitis, bronchial asthma, including the raw material of following parts by weight: calabash 10 parts of reed brill, Radix Puerariae 3 parts, Folium Eucommiae 3 parts, Caulis Gneti 3 parts, Radix Cudraniae 3 parts, Radix Polygalae fallacis 3 parts, Thallus Laminariae (Thallus Eckloniae) 3 parts, eucalyptus leaves 3 Part, Herba speranskiae tuberculatae 1 part, fevervine 1 part and Radix Salviae Miltiorrhizae 1 part.
Its preparation method, comprises the following steps:
Step one, the powder of Radix Puerariae of above-mentioned weight portion is broken into the fine powder of more than 100 mesh, standby；
Step 2, the calabash of above-mentioned weight portion is bored boiling water extraction 2 times, each 2 hours, merges twice extraction filtrate, Concentrating under reduced pressure obtains the first extractum that relative density is 1.09；
Step 3, Folium Eucommiae, Caulis Gneti, Radix Cudraniae, Radix Polygalae fallacis, Thallus Laminariae (Thallus Eckloniae) and eucalyptus leaves by above-mentioned weight portion mix Closing, add water, intense fire decocts 1 as a child slow fire boiling 2 hours, that the filtrate reduced in volume of filtration obtains relative density is 1.25 Two extractum；
Step 4, Herba speranskiae tuberculatae by above-mentioned weight portion, fevervine and Radix Salviae Miltiorrhizae mixing, add water, and it is the most civilian that intense fire decocts 0.5 Fire decocts 2 hours, and the filtrate reduced in volume of filtration obtains the 3rd extractum that relative density is 1.2；
Step 5, by the first extractum, the second extractum and the 3rd extractum mixing and with in step one powder of Radix Puerariae mix, i.e. Yao medicinal composition described in, and make tablet.
Embodiment 2
A kind of Yao medicinal composition treating chronic bronchitis, bronchial asthma, including the raw material of following parts by weight: calabash 30 parts of reed brill, Radix Puerariae 6 parts, Folium Eucommiae 5 parts, Caulis Gneti 5 parts, Radix Cudraniae 5 parts, Radix Polygalae fallacis 5 parts, Thallus Laminariae (Thallus Eckloniae) 5 parts, eucalyptus leaves 5 Part, Herba speranskiae tuberculatae 2 parts, fevervine 2 parts and Radix Salviae Miltiorrhizae 2 parts.
Its preparation method, comprises the following steps:
Step one, the powder of Radix Puerariae of above-mentioned weight portion is broken into the fine powder of more than 100 mesh, standby；
Step 2, the calabash of above-mentioned weight portion is bored boiling water extraction 2 times, each 2 hours, merges twice extraction filtrate, Concentrating under reduced pressure obtains the first extractum that relative density is 1.09；
Step 3, Folium Eucommiae, Caulis Gneti, Radix Cudraniae, Radix Polygalae fallacis, Thallus Laminariae (Thallus Eckloniae) and eucalyptus leaves by above-mentioned weight portion mix Closing, add water, intense fire decocts 1 as a child slow fire boiling 2 hours, that the filtrate reduced in volume of filtration obtains relative density is 1.25 Two extractum；
Step 4, Herba speranskiae tuberculatae by above-mentioned weight portion, fevervine and Radix Salviae Miltiorrhizae mixing, add water, and it is the most civilian that intense fire decocts 0.5 Fire decocts 2 hours, and the filtrate reduced in volume of filtration obtains the 3rd extractum that relative density is 1.2；
Step 5, by the first extractum, the second extractum and the 3rd extractum mixing and with in step one powder of Radix Puerariae mix, i.e. Yao medicinal composition described in, is dried to powder and makes capsule.
Embodiment 3
A kind of Yao medicinal composition treating chronic bronchitis, bronchial asthma, including the raw material of following parts by weight: calabash 25 parts of reed brill, Radix Puerariae 4 parts, Folium Eucommiae 4 parts, Caulis Gneti 4 parts, Radix Cudraniae 4 parts, Radix Polygalae fallacis 4 parts, Thallus Laminariae (Thallus Eckloniae) 4 parts, eucalyptus leaves 4 Part, Herba speranskiae tuberculatae 1 part, fevervine 1 part and Radix Salviae Miltiorrhizae 1 part.
Its preparation method, comprises the following steps:
Step one, the powder of Radix Puerariae of above-mentioned weight portion is broken into the fine powder of more than 100 mesh, standby；
Step 2, the calabash of above-mentioned weight portion is bored boiling water extraction 2 times, each 2 hours, merges twice extraction filtrate, Concentrating under reduced pressure obtains the first extractum that relative density is 1.09；
Step 3, Folium Eucommiae, Caulis Gneti, Radix Cudraniae, Radix Polygalae fallacis, Thallus Laminariae (Thallus Eckloniae) and eucalyptus leaves by above-mentioned weight portion mix Closing, add water, intense fire decocts 1 as a child slow fire boiling 2 hours, that the filtrate reduced in volume of filtration obtains relative density is 1.25 Two extractum；
Step 4, Herba speranskiae tuberculatae by above-mentioned weight portion, fevervine and Radix Salviae Miltiorrhizae mixing, add water, and it is the most civilian that intense fire decocts 0.5 Fire decocts 2 hours, and the filtrate reduced in volume of filtration obtains the 3rd extractum that relative density is 1.2；
Step 5, by the first extractum, the second extractum and the 3rd extractum mixing and with in step one powder of Radix Puerariae mix, i.e. Yao medicinal composition described in.
Step 6, in Yao medicinal composition, add appropriate correctives, preservative, suspending agent or solubilizing agent, add water and shake up, fill Dress, obtains oral liquid.
Embodiment 4
A kind of Yao medicinal composition treating chronic bronchitis, bronchial asthma, including the raw material of following parts by weight: calabash 15 parts of reed brill, Radix Puerariae 4 parts, Folium Eucommiae 4 parts, Caulis Gneti 4 parts, Radix Cudraniae 4 parts, Radix Polygalae fallacis 4 parts, Thallus Laminariae (Thallus Eckloniae) 4 parts, eucalyptus leaves 4 Part, Herba speranskiae tuberculatae 1 part, fevervine 1 part and Radix Salviae Miltiorrhizae 1 part.
Embodiment 5
On the basis of embodiment 4, present invention also offers a kind of pharmaceutical preparation treating chronic bronchitis, with described Pharmaceutical composition is effective ingredient, collectively constitutes with pharmaceutically acceptable auxiliary element.
Embodiment 6
On the basis of embodiment 4, present invention also offers a kind of pharmaceutical preparation treating bronchial asthma, with described medicine Compositions is effective ingredient, collectively constitutes with pharmaceutically acceptable auxiliary element.
In order to illustrate that the present invention treats the effect of the Yao medicinal composition of bronchial asthma, carry out with its pharmaceutical preparation prepared Following clinical research, result of the test is as follows:
Diagnostic criteria
Symptom: cough and asthma, gurgling with sputum sound, expectorant Huang is sticky, and expectorant is not the most smooth, and repeated relapsing is uncomfortable in chest, red tongue yellow fur Greasy.
Sign: during outbreak, thorax expands, and intercostal space is full, and auscultation two lung has wheezing sound widely, has wet during accompanying infection Rale, the dimnition of cardiac sound, prolonged illness has emphysema feature.
Efficacy assessment standard
1, cure: clinical symptom disappearance, do not recur in 1 year.
2, effective: clinical symptom relief, attack times significantly reduces.
Case-data, 50 example Bronchial Asthmas, the age between 15-65 year, 34 years old mean age；Man's 28 examples, female 22 examples, the course of disease 3 months-15 years.
Therapeutic Method:
Use the oral liquid of preparation in embodiment 3, every day 2 times, each take 30 milliliters, take continuously 1 month.
Therapeutic effect: cure 47 examples, do not fall ill, meet criterion of cure for more than 1 year；2 examples are effective, and wherein 1 example is during 1 year Recurred once, an other example clinical symptom relief；1 example is invalid, and total effective rate reaches 98%.
Model case
Case one: Xiao, man 26 years old, suffer from bronchial asthma 2 years, dyspnea during outbreak, can not crouch night, expectorant Huang is sticky, After this outbreak, use the oral liquid of the present invention, after taking one month continuously, transference cure, follow up a case by regular visits to not recur after 1 year.
In order to the effect of the Yao medicinal composition of the treatment chronic bronchitis of the present invention, the pharmaceutical preparation prepared with it are described Carrying out following clinical research, result of the test is as follows:
Diagnostic criteria
Symptom: cough, expectoration or companion pant, annual morbidity 3 months, continuous 2 years or above person；Other hearts, lung can be got rid of Disease (such as pulmonary tuberculosis, asthma, bronchiectasis, pulmonary carcinoma, heart disease etc.) person；Fall ill less than 3 months every year, and have clear and definite visitor See and check that foundation (such as x-ray, lung function tests etc.) person is the most diagnosable.
Efficacy assessment standard
1, curing: clinical symptoms and pulmonary rale substantially disappear, X-ray chest-fluoroscopy shade disappears, and more than 1 year without recurrence.
2, effective: clinical symptoms disappears substantially, and pulmonary rale is obviously reduced, X-ray chest-fluoroscopy dash area absorbs.
3, invalid: clinical symptoms and x-ray check without significant change.
Case-data, 120 example chronic bronchitis patients, the age between 48-65 year, 58 years old mean age；Man's 58 examples, Female 62 example, course of disease 3-15.
Therapeutic Method:
Use the capsule of preparation in embodiment 2, every day 2 times, each take one, take continuously 6 months.
Therapeutic effect: 120 patients, after treatment, cure 115 examples, effective 5 examples, invalid 0 example, cure rate 95.8%, Effective percentage 100%.
Model case
Case one: grandson so-and-so, female, 52 years old, suffer from chronic bronchitis 6 years, after taking medicine one week half the circumference of the sleeve where it joins the shoulder face upward breathe heavily number of times reduce, breast Vexed alleviating, breathe heavily and subtract greatly after two weeks, further consultation in about 3 months, its pain uncomfortable in chest disappears substantially, without asthma, coughs once in a while, advises patient Continuous use 3 months again, all diseases disappear.
Case two: Chen, man 61 years old, suffer from chronic bronchitis 10 years, breast is tubbiness, and double lungs are heard and dry moist rale, breast Sheet shows that bilateral intercostal space is broadening, body void spontaneous perspiration, it is impossible to flat sleeping, cough, expectoration.After taking medicine one week, flu takes a turn for the better, and spontaneous perspiration alleviates； After two weeks, flu is cured, and can put down sleeping, cough once in a while；Take medicine 3 months all transference cures, continue to take medicine 3 months, with kind its After.
Although embodiment of the present invention are disclosed as above, but it is not restricted in description and embodiment listed Using, it can be applied to various applicable the field of the invention completely, for those skilled in the art, and can be easily Realizing other amendment, therefore under the general concept limited without departing substantially from claim and equivalency range, the present invention does not limit In specific details with shown here as the embodiment with description.

Claims (5)

1. the Yao medicinal composition treating chronic bronchitis, bronchial asthma, it is characterised in that include following parts by weight Raw material: calabash bore 10-30 part, Radix Puerariae 3-6 part, Folium Eucommiae 3-5 part, Caulis Gneti 3-5 part, Radix Cudraniae 3-5 part, Radix Polygalae fallacis 3-5 part, Thallus Laminariae (Thallus Eckloniae) 3-5 part, eucalyptus leaves 3-5 part, Herba speranskiae tuberculatae 1-2 part, fevervine 1-2 part and Radix Salviae Miltiorrhizae 1-2 part.
Treat the Yao medicinal composition of chronic bronchitis, bronchial asthma the most as claimed in claim 1, it is characterised in that bag Include the raw material of following parts by weight: calabash bores 15-25 part, Radix Puerariae 4 parts, Folium Eucommiae 4 parts, Caulis Gneti 4 parts, Radix Cudraniae 4 parts, Hemerocallis citrina Baroni Thalictrum omeiense W. T. Wang et S. H. Wang 4 parts, Thallus Laminariae (Thallus Eckloniae) 4 parts, eucalyptus leaves 4 parts, Herba speranskiae tuberculatae 1 part, fevervine 1 part and Radix Salviae Miltiorrhizae 1 part.
3. the preparation method of a Yao medicinal composition, it is characterised in that count by weight, comprise the following steps:
Step one, 3-6 part powder of Radix Puerariae is broken into the fine powder of more than 100 mesh, standby；
Step 2,10-30 part calabash being bored boiling water extraction 2 times, each 2 hours, merges twice extraction filtrate, concentrating under reduced pressure obtains Relative density is first extractum of 1.09；
Step 3, by 3-5 part Folium Eucommiae, 3-5 part Caulis Gneti, 3-5 part Radix Cudraniae, 3-5 part Radix Polygalae fallacis, 3-5 part Thallus Laminariae (Thallus Eckloniae) and 3-5 part eucalyptus leaves mixes, and adds water, and intense fire decocts 1 as a child slow fire boiling 2 hours, is obtained relatively by the filtrate reduced in volume of filtration Density is second extractum of 1.25；
Step 4,1-2 part Herba speranskiae tuberculatae, 1-2 part fevervine and 1-2 part Radix Salviae Miltiorrhizae being mixed, add water, intense fire decocts 0.5 the most civilian Fire decocts 2 hours, and the filtrate reduced in volume of filtration obtains the 3rd extractum that relative density is 1.2；
Step 5, by the first extractum, the second extractum and the 3rd extractum mixing and with in step one powder of Radix Puerariae mix, obtain institute The Yao medicinal composition stated.
4. the pharmaceutical preparation treating chronic bronchitis, it is characterised in that combined by the precious jade medicine described in claim 1 or 2 Thing and pharmaceutically acceptable adjuvant composition.
5. the pharmaceutical preparation treating bronchial asthma, it is characterised in that by the Yao medicinal composition described in claim 1 or 2 Form with pharmaceutically acceptable adjuvant.
CN201610741757.5A 2016-08-26 2016-08-26 Treatment chronic bronchitis, the Yao medicinal composition of bronchial asthma Pending CN106177283A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610741757.5A CN106177283A (en) 2016-08-26 2016-08-26 Treatment chronic bronchitis, the Yao medicinal composition of bronchial asthma

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610741757.5A CN106177283A (en) 2016-08-26 2016-08-26 Treatment chronic bronchitis, the Yao medicinal composition of bronchial asthma

Publications (1)

Publication Number Publication Date
CN106177283A true CN106177283A (en) 2016-12-07

Family

ID=57527019

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610741757.5A Pending CN106177283A (en) 2016-08-26 2016-08-26 Treatment chronic bronchitis, the Yao medicinal composition of bronchial asthma

Country Status (1)

Country Link
CN (1) CN106177283A (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1899556A (en) * 2006-07-19 2007-01-24 罗世斌 Medicine for treating trachitis and asthma

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1899556A (en) * 2006-07-19 2007-01-24 罗世斌 Medicine for treating trachitis and asthma

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
刘春生等: "买麻藤", 《精编<本草纲目>药物彩色图鉴》 *
尹显洪主编: "葫芦钻", 《瑶药常用植物药化学与药理研究》 *
戴义龙等: "黄花倒水莲", 《450种中草药彩色图鉴》 *
杨卫平等: "桉树叶", 《新编中草药图谱及常用配方（五）》 *

Similar Documents

Publication Publication Date Title
CN103768541B (en) A kind of medicine for the treatment of chronic bronchitis
CN105582428A (en) Transdermal patch for acupoint sticking therapy and preparation method thereof
CN101085269B (en) Internal-applied traditional Chinese medicine composition for treating lung cancer
CN104042713B (en) A kind of Chinese medicine composition for the treatment of bronchial asthma
CN106109694A (en) A kind of Chinese medicine formula treating asthma
CN103638488A (en) Traditional Chinese medicine composition for treating pleurisy
CN104474256B (en) A kind of oral solution for treating pulmonary infection of AIDS
CN102198182A (en) Medicament for treatment of interstitial pneumonia
CN106177283A (en) Treatment chronic bronchitis, the Yao medicinal composition of bronchial asthma
CN110496200A (en) It is a kind of to treat phthisical Chinese medicine composition and its preparation method and application
CN104189605A (en) Traditional Chinese preparation for treating acute nasopharyngitis and preparation method thereof
CN101181509B (en) Chinese medicine prescription orally taken for curing pulmonary emphysema
CN101979015B (en) Chinese medicinal preparation for treating respiratory diseases of chronic tracheitis, emphysema and pulmonary heart disease
CN102614322A (en) Medicinal composition for treating child asthmatic suffocating pneumonia
CN105687684A (en) Traditional Chinese medicine preparation for treating chronic obstructive pulmonary disease
CN106215097A (en) A kind of Chinese medicine preparation treating chronic cardiopulmonary disease and preparation method thereof
CN104258361A (en) Traditional Chinese medicine composition for treating infantile asthma
CN105168838A (en) Traditional Chinese medicine composition for treating sphagitis and preparation thereof
CN104587278A (en) Traditional Chinese medicinal composition for treating pleural effusion and preparation method
CN104274702A (en) Traditional Chinese medicine preparation for treating chronic cardiac-failure qi deficiency and blood stasis and syndrome of internal stagnation of fluid-dampness
CN104027571A (en) Traditional Chinese medicine composition for treating chronic pulmonary heart disease
CN102641374B (en) Traditional Chinese decoction for treating chronic bronchitis
CN109646649A (en) A kind of Chinese drugs agentia for treating palpitaition flu
CN103705742A (en) Traditional Chinese medicine composite for treating lung-kidney qi deficiency type emphysema
CN108939019A (en) A kind of Chinese drugs agentia for treating palpitaition flu

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20161207