CN106176214B - Blood separation for extracting the growth factor for being rich in blood platelet and extraction element - Google Patents
Blood separation for extracting the growth factor for being rich in blood platelet and extraction element Download PDFInfo
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- CN106176214B CN106176214B CN201510566495.9A CN201510566495A CN106176214B CN 106176214 B CN106176214 B CN 106176214B CN 201510566495 A CN201510566495 A CN 201510566495A CN 106176214 B CN106176214 B CN 106176214B
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Abstract
It is centrifuged in the state that the blood for extracting the growth factor rich in blood platelet of the present invention detaches and extraction element contains blood in the receiving space portion for being formed in the lower part of main body tube, it will be injected into the separated space portion of main body tube as the white blood cell of the separating layer for the blood being centrifuged, it, thus can be by once centrifuging and a container is carried out at the same time the separation of blood and the extraction operation of Platelet Concentrate later in conjunction with upper cap and only to collect and extract Platelet Concentrate in such a way that the passage portion with main body tube is connected to.
Description
Technical field
The blood that the present invention relates to a kind of for extracting the growth factor rich in blood platelet detaches and extraction element, especially
Even if be related to a kind of construct is carried out at the same time separation and concentration operation and only by once centrifuging with an available container
Also it can realize separation and extract the blood separation for extracting the growth factor rich in blood platelet that the mode of operation is improved
And extraction element.
Moreover, it relates to which a kind of construction is with the most white blood cell using syringe recycling extraction in a reservoir
Mode improved for extract rich in blood platelet growth factor blood detach and extraction element.
Background technology
The blood of intravascular cycle in human body or animal body executes such as inferior multiple functions：The oxygen that will be sucked by lung
It is transported to histocyte, from tissue to pulmonary delivery carbon dioxide and is discharged into outside, the nutrient absorbed by alimentary canal is defeated
It is sent to internal organs or histocyte, as the decomposition product of tissue, extra substance for organism is transported to kidney simultaneously
It is discharged in vitro, the hormone (hormone) secreted from incretory is transported to effect organ, tissue, is uniformly dispersed body
Heat and fixedly keep body temperature, in addition to this, destroyed to invading the bacterium in organism, foreign matter etc., Non-toxic.
Though this blood also serves as to judge the leading indicator of various diseases or health status, life is rich in blood
The blood platelet and white blood cell of the long factor (Growth factor) are used with therapeutic purposes.
Blood includes red blood cell, white blood cell, blood platelet etc., wherein blood platelet is primarily present in blood plasma, and blood plasma is divided into rich blood
Platelet-poor plasma (Platelet Rich Plasma, PRP) layer and platelet poor plasma (Platelet Poor Plasma, PPP)
Layer.
Referred to as PRP (Platelet Rich Plasma：Blood platelet concentrate blood plasma) the blood plasma rich in blood platelet be located at blood
Slurry relatively under position, including cell factor (cytokine), platelet derived growth factor (Platelet Derived
Growth Factor, PDGF), transforming growth factor-beta 1 (Transforming Growth Factor-BETA1, TGF-
BETA1), the growth factors such as vascular endothelial growth factor (Vascular Endothelial Growth Factor, VEGP),
It is especially effective to skin disease and Wound healing that it has been illustrated in the data such as paper.
In addition, referred to as PPP (Platelet Poor Plasma：Blood platelet poor plasma) almost platelet-free blood plasma
As autoblood filler or autologous plasma cosmetics.
Wherein, Platelet Concentrate (PRP) layer only accounts for 1% or so of acquired blood, and viscosity is higher and is attached to
Red blood cell, therefore, it is difficult to acquire.If by the Platelet Concentrate (PRP) be transplanted to affected part, particularly inside the knee, ligament,
Muscle etc. is then played the effect for stimulating stem cell around and contributing to Hemapoiesis, therefore is used with therapeutic purposes always,
But it is difficult to acquire due to its amount is few and is attached to red blood cell, if red blood cell enters into the human body, very big pain can be caused
Hardship, and inflammation can be also therefore generated, so focus on the technology of the Platelet Concentrate (PRP) of acquisition removal red blood cell.
However, currently in order to extraction Platelet Concentrate layer, has and was detached by centrifugal separation processes, a secondary centrifuging
The process of Cheng Jinhang concentrations, the process is that blood is being injected into the first separation container with top, lower liquid room
After in lower liquid room, the first separation container to being injected with blood is once centrifuged, and promotion is once centrifuging
In the process separated white blood cell and buffy (Buffy coat) layer and make it etc. and moved to top liquid chamber.
Hereafter, there is following process：The white blood cell and buffy coat of portion's liquid chamber are served to secondary separation container sidesway,
It carries out secondary centrifuging separation again and it is made to wait concentration, to extract Platelet Concentrate.
At this point, having following problem：Not only in the blood once centrifuged to the secondary separation container sidesway warp let-off
When generating loss during separating layer, and once centrifuging relatively complicated operation, secondary centrifuging detached job and operation
Between it is longer.
Invention content
[the invention project to be solved]
The present invention proposes that its purpose is to provide a kind of constructions with such as lower section in order to solve the various problems
The blood for extracting the growth factor rich in blood platelet that formula is improved detaches and extraction element：Using container into
Row simplifies centrifugal separation processes to extract and acquire the process of Platelet Concentrate, even if only by once centrifuging
Process can also realize separation and the extraction operation of Platelet Concentrate.
Another object of the present invention is to provide in a kind of separating layer of the construction easily to realize separated blood
The blood for extracting the growth factor rich in blood platelet that the mode of separation and the extraction of blood platelet is improved is detached and is carried
Take device.
Another object of the present invention is to provide a kind of construct with the big portion using syringe recycling extraction in a reservoir
Divide the blood separation for being used to extract the growth factor rich in blood platelet and extraction element that the mode of white blood cell is improved.
[means to solve the problem]
The present invention to reach the purpose has：Main body tube forms the receiving space portion of accommodating blood in lower part,
The passage portion with rake and upper end opening in such a way that internal diameter is narrower than lower part is formed on the top in the receiving space portion,
And it is formed with separated space portion, the separated space portion receiving is via the passage portion by centrifugation of the blood
A separating layer part for the blood of separation；
Sliding block (slider) is attached to the receiving space portion in a manner of slidably (sliding), via described logical
Road portion is forced through the separating layer of the blood of the centrifugation and separation to separated space portion side；And
Upper cap (cap), is detachably attached to the upper end of the main body tube, central lower formed with
The main body tube in conjunction with when the engaging portion that is combined with the upper end of the passage portion, and there is storage unit, the storage unit is with to institute
The extended mode of a side lower part for stating engaging portion is formed, small for the deshydremia in the separating layer of blood when the sliding block rises
Plate flows into and accommodates the Platelet Concentrate in the separating layer of the blood；And
The upper cap forms inlet, the first outflux and the second outflux in upper surface, the inlet for
The first syringe to inject the blood by the passage portion enters, and first outflux accommodates for being extracted to outside
Second syringe of the Platelet Concentrate in the storage unit enters, and second outflux is housed in for being extracted to outside
The third syringe of the white blood cell in the separated space portion enters,
Has guiding tube, the guiding tube is attached to the second outlet side, extends under the separated space portion
Until portion, the needle (needle) of the third syringe is guided.
In addition, the device of the invention：In the inlet, the first outflux, the second outflux in conjunction with for described each
First rubber stopper of the elasticity of the needle entrance of the first syringe, the second syringe, third syringe, the second rubber stopper, third rubber
Rubber plug.
In addition, the device of the invention：The guiding tube include be attached to the third rubber stopper major diameter portion, with institute
State major diameter portion bias mode extended minor diameter and the rake that connect the major diameter portion with minor diameter,
In the lower end of the minor diameter, be formed with for the third syringe needle end by notch.
In addition, the device of the invention is also equipped with lower cover, the lower cover is incorporated in the lower part of the main body tube, prevents institute
It states sliding block to fall off, and through-hole is formed in center, in order to the elevating mechanism for feeding to the upside promotion sliding block and it being made to increase
Disengaging.
In addition, the device of the invention：The upper cap is also equipped with separating plate, and the separating plate is in a manner of vertically outstanding
It is formed in the bottom surface of the storage unit.
[The effect of invention]
The present invention has the following effects that.
First, it forms the separated space portion divided using intermediate passage portion as medium in the inside of main body tube and receiving is empty
Between portion, the storage unit configuration being connected to passage portion when combining upper cap therefore has the following effects that in the lower part of upper cap：It can
By a container separation and the separating layer of extraction blood, when thus preventing the loss in transfer, and substantially shortening operation
Between.
Second, the present invention is to realize the separation and extraction of blood in a container by centrifugal separation processes,
Therefore the advantages of there is the convenience of operation to improve, and the efficiency of operation can be improved.
Third, though the depth for containing the separated space portion 104 of white blood cell is relatively deep, the needle 31 of third syringe 30 is drawn
Guiding tube 400 is led, therefore can realize stable recycling.
4th, receiving space portion 102 is divided with separated space portion 104 and under separated space portion 104 by rake 105a
Portion is more towards the inner wall surface side of main body tube 100, then space is narrower.In this case, needle 31 of the guiding in guiding tube 400
End be located at position corresponding with the middle section of rake 105a, therefore, it is difficult to extract the separation for remaining in and gradually becoming narrow
The white blood cell of the lowest part of spatial portion 104, but the minor diameter 402 of the lower side because being located at guiding tube 400 in an eccentric manner
And the end of notch 402a and curved guide needle 31, to the white blood of the extractable lowest part for remaining in separated space portion 104
Ball.
Description of the drawings
Fig. 1 is point for indicating the blood separation and extraction element for extracting the growth factor rich in blood platelet of the present invention
Solve stereogram.
Fig. 2 is to look up the exploded perspective view for indicating Fig. 1.
Fig. 3 is the bonding state figure of Fig. 1.
Fig. 4 is the engaging portion for indicating the present invention and the stereogram of storage unit.
Fig. 5 a, Fig. 5 b, Fig. 5 c, Fig. 5 d, Fig. 5 e, Fig. 5 f, Fig. 5 g are the use shapes for sequentially indicating the use state of the present invention
State figure.
Fig. 6 is the partial cross-sectional perspective view for another embodiment for indicating the storage unit of the present invention.
Fig. 7 is the usage state diagram of Fig. 6.
Fig. 8 is the sectional view for another embodiment for indicating the device of the invention.
Fig. 9 is the stereogram of the guiding tube of Fig. 8.
[explanation of symbol]
10：First syringe
20：Second syringe
30：Third syringe
31：Needle
100：Main body tube
102：Receiving space portion
104：Separated space portion
105：Passage portion
105a、403：Rake
200：Sliding block
210：First plunger member
220：Second plunger member
250：Lower cover
255：Through-hole
300：Upper cap
300a：First outflux
300b：Second outflux
300c：Inlet
302：Second rubber stopper
303：Third rubber stopper
304：First rubber stopper
310：Engaging portion
312：Combined hole
320：Storage unit
330：Separating plate
400：Guiding tube
401：Major diameter portion
402：Minor diameter
402a：Notch
P：Platelet Concentrate
R：Red blood cell
W：White blood cell
Specific implementation mode
Centrifugation point is carried out in the state that the present invention contains blood in the receiving space portion for being formed in the lower part of main body tube
From, so that the white blood cell as the separating layer for the blood being centrifuged is separated in the separated space portion of main body tube, later with
Main body tube passage portion connection mode combination upper cap and so as to only collect and extract Platelet Concentrate, thus can pass through one
Secondary centrifugation and a container carry out the separation of blood and the extraction operation of Platelet Concentrate and white blood cell.
Hereinafter, with reference to attached drawing, preferred embodiment of the present invention will be described in detail.
If illustrated referring to figs. 1 to Fig. 5, the blood for extracting the growth factor rich in blood platelet of the present invention
Separation and extraction element have：Main body tube 100 forms the receiving space portion 102 of accommodating blood, in receiving sky in lower part
Between the top in portion 102 form the passage portion 105 with rake 105a and upper end opening in such a way that internal diameter is narrower than lower part, and
Be formed with separated space portion 104, the receiving of separated space portion 104 via the passage portion 105 by the blood from
The heart detaches and a separating layer part for the blood of separation；Sliding block 200 is slidably coupled to the receiving space portion
102, the blood of the centrifugation and separation is forced through to 104 side of separated space portion via the passage portion 105
Separating layer；And upper cap 300, it is detachably attached to the upper end of the main body tube 100, is formed in central lower
The engaging portion 310 combined with the upper end of the passage portion 105 when being combined with the main body tube 100, and there is storage unit 320,
The storage unit 320 is formed in such a way that the side lower part to the engaging portion 310 is extended, when the sliding block 200 rises, is supplied
Platelet Concentrate P in the separating layer of blood is flowed into and is accommodated the Platelet Concentrate P in the separating layer of the blood.
It is formed with inlet 300c, the first outflux 300a and the second outflux in the upper surface of the upper cap 300
300b, the inlet 300c for injected by the passage portion 105 blood the first syringe 10 enter, institute
The first outflux 300a is stated for being housed in the second syringe of the Platelet Concentrate P in the storage unit 320 to external extraction
20 enter, and the second outflux 300b is for being housed in the third of the white blood cell W in the separated space portion 104 to external extraction
Syringe 30 enters.
Guiding tube 400, the guiding tube 400 is combined to extend to the separated space portion in the sides the second outflux 300b
Until 104 lower part, the needle 31 of the third syringe 30 is guided.
In the inlet 300c, the first outflux 300a, the second outflux 300b in conjunction with for each first note
Emitter, the second syringe, third syringe 10,20,30 needle (needle) enter elasticity the first rubber stopper, the second rubber
Plug, third rubber stopper 304,302,303.
If be illustrated in more details, separated space portion 104 is to be with passage portion 105 in the upside of main body tube 100
Medium and demarcate the construction come with receiving space portion 102, and in following construction：When the sliding block 200 rises, for use by institute
The separating layer part of blood stated the centrifugation of blood and detached is flowed by the passage portion 105 and accommodates the blood
Separating layer a part.
In addition, in the lower part of main body tube 100, lower cover 250, the lower cover 250 is detachably combined to prevent
The sliding block 200 falls off, and is formed with through-hole 255, and the sliding block 200 is pushed and the lifting that makes it increase in order to feed to upside
Tool disengaging (not shown).
Passage portion 105 is formed in the upper side in receiving space portion 102 in a vertical manner, is narrower than receiving space portion with internal diameter
The mode of 102 internal diameter has rake 105a.
Receiving space portion 102 is divided with separated space portion 104 and under separated space portion 104 by rake 105a as a result,
More towards the inner wall surface side of main body tube 100, then the space for accommodating white blood cell W is narrower in portion.
The engaging portion 310 of upper cap 300 is formed with the combined hole 312 of lower openings, to be engaged to the upper of passage portion 105
End peripheral surface.
Storage unit 320 has the structure formed in a manner of the position that bottom face is located at less than the lower end of engaging portion 310
It makes.
That is, storage unit 320 has the construction that receiving passes through the Platelet Concentrate P that passage portion 105 flows into.
Sliding block 200 includes the first plunger member, the second plunger member 210,220.
First plunger member 210 combines sealing (sealing) component of multiple annular states in peripheral surface periphery, in order to keep
It is airtight, and when carrying out vertical motion with the volume in uniform pressure diminution receiving space portion 102.
Second plunger member 220 is silicon (silicon) material, is incorporated in the lower part of first plunger member 210, is utilizing liter
When drop tool makes the first plunger member 210 carry out vertical motion, the first plunger member 210 can be protected.
First plunger member 210 has following construction：By by the lifting tool (actuators such as cylinder (cylinder) especially
(actuator) or the finger of people) transmit climbing power and carry out vertical motion, along the receiving space portion 102 of main body tube 100
Inner peripheral surface rises.
At this point, lifting tool can enter the inside in receiving space portion 102 by the through-hole 255 of lower cover 250, to sliding block
200 assign unlifting pressure.
When sliding block 200 carries out vertical motion, the extracted amount (for example, 1.0~2.5cc) of Platelet Concentrate P can be according to height
Low variation and change.
After the Platelet Concentrate P for being collected into set volume, it can will be extracted in the storage by the second syringe 20
The Platelet Concentrate P for depositing portion 320 extracts outside.
On the other hand, storage unit 320 can also be integrally formed to upper cap 300 with engaging portion 310 with a main body
Bottom surfaces, or detachably it is attached to the lower part of upper cap 300.
Fig. 8 and Fig. 9 indicates another embodiment of the device of the invention.
The present embodiment indicates that the modification of the guiding tube 400, the guiding tube 400 have following construction：Including combination
To the major diameter portion 401 of the third rubber stopper 303, with the mode extended minor diameter eccentric with the major diameter portion 401
402 and the rake 403 that connect the major diameter portion 401 with minor diameter 402, and under the minor diameter 402
End be formed with the end for the needle 31 of the third syringe 30 by notch 402a.
If as follows to having the function of that the present invention of this composition illustrates.
First, with reference to Fig. 5 a, the blood for extracting the growth factor rich in blood platelet of the invention detaches and extraction dress
It sets after so that the first syringe 10 for being filled with blood is passed through to 304 side of the first rubber stopper, by passage portion 105 to main body tube
Blood is injected in 100 receiving space portion 102, using centrifugal separator to being infused in receiving space portion 102 as Fig. 5 b
Blood be centrifuged.
The injection rate of blood can be injected according to 30~50cc or so.
At this point, upper cap 300 keeps the state for being incorporated in the top of main body tube 100, so as to close in centrifugal separation processes
Seal separated space portion 104.
If centrifugation terminates, as shown in Fig. 5 c before sliding block 200 carries out lifting action, make engaging portion 310
It is moved with the upward side of the mode being separated from each other with passage portion 105.
If centrifugation terminates, the blood is divided into red blood cell R, white blood cell W, Platelet Concentrate P, according to proportion
Difference and white blood cell W, Platelet Concentrate P, red blood cell R are sequentially separated into from upside.
Secondly, if lifting tool is made to enter the inside of through-hole 255 of lower cover 250 and to upside ejection sliding block 200,
Sliding block 200 carries out vertical motion in the inside in receiving space portion 102 and reduces in the receiving space portion 102 of accommodating blood separating layer
Volume.
Sliding block 200 makes W layers of white blood cell in the separating layer for the blood being stored in receiving space portion 102 pass through when rising
Passage portion 105 is injected into the separated space portion 104 of main body tube 100.
The vertical motion of the sliding block 200 is to rise to until injections of the white blood cell W into separated space portion 104 terminate.
At this point, Platelet Concentrate P is located at the inside of passage portion 105, red blood cell R holdings are housed in receiving space portion 102
The state of lower part.
Hereafter, as fig 5d, if upper cap 300 is made to carry out lowering action again and make engaging portion 310 to be engaged to
The mode of the end of passage portion 105 combines, then the inside in receiving space portion 102 with the storage unit 320 of upper cap 300 to connect each other
Logical mode combines.
As depicted in fig. 5e, if after the engaging portion of upper cap 300 310 is engaged to passage portion 105, operating personnel is sharp again
So that sliding block 200 is carried out secondary rising with lifting tool, is then filled with the receiving space portion 102 of a separating layer part for blood
Volume further reduce and Platelet Concentrate P is flowed into the storage unit 320 of upper cap 300 by the upper end of passage portion 105
Inside.
The secondary vertical motion of sliding block 200 proceeds to until inflows of the Platelet Concentrate P into storage unit 320 terminate.
The capacity for being stored into the Platelet Concentrate P of storage unit 320 can be changed according to the injection rate of blood and the form quality of blood,
Substantially 1.5~3.0cc of concentration storage or so.
If inflows of the Platelet Concentrate P into storage unit 320 terminates, as shown in figure 5f, operating personnel executes as follows
Operation：Make the second syringe 20 by upper cap 300 second rubber stopper 302 by outside extraction be stored in storage unit 320
Platelet Concentrate (PRP).
Secondly, as shown in fig. 5g, following operation is executed：Make third rubber stopper of the third syringe 30 by upper cap 300
303 and be stored in the white blood cell W in separated space portion 104 to external extraction.At this point, the needle 31 of third syringe 30 is directed into
Guiding tube 400 and can steadily be directed to the deeper separated space portion of depth 104.
On the other hand, Fig. 6 and Fig. 7 is the figure for another embodiment for indicating the storage unit of the present invention.
Another embodiment of the storage unit of the present invention is identical as the inscape of the preceding embodiment illustrated before, but is also equipped with
Separating plate 330, the separating plate 330 are formed in the bottom surface of storage unit 320 in such a way that direction vertically upward is outstanding, to incite somebody to action
The inside of storage unit 320 is divided into left side and right side in figure.
Separating plate 330 executes following function：Even if being concentrated due to maloperation caused by the excessive vertical motion of sliding block 200
Blood platelet P and red blood cell R is mixed into unsegregated state in storage unit 320, and difference of specific gravity can also be used and keep institute mixed
The separating layer of blood is separated from each other in divided storage unit 320.
When sliding block 200 exceedingly rises, there are following worries：The Platelet Concentrate P being filled in receiving space portion 102
It is flowed into storage unit 320 by passage portion 105 with red blood cell R.
In this case, even if Platelet Concentrate P and red blood cell R is mixed into is divided into left and right space by separating plate 33
Storage unit 320 in, the difference of specific gravity of Platelet Concentrate P and red blood cell R can also be used and in the storage unit 320 in left side and right side
Interior separation.
That is, if after being flowed into the right side storage unit 320 of separating plate 330 with respect to the Platelet Concentrate P for being lighter than red blood cell R
Make red blood cell R flow into, then cross the top of separating plate 330 and be flowed into left side storage unit 320 space interior.
Platelet Concentrate P is separated to 330 benchmark of separating plate in the storage unit 320 in left side, and red blood cell R keeps separation to exist
State in right side storage unit 320.
Hereafter, the process of separated Platelet Concentrate P and the mistake illustrated before are extracted using extracting tools such as syringes
Cheng Xiangtong.
On the other hand, with reference to Fig. 5 g, receiving space portion 102 and separated space portion 104 is divided by rake 105a and is detached
The lower part of spatial portion 104 is more towards the inner wall surface side of main body tube 100, then space is narrower.
In this case, as shown in fig. 5g, guiding is located in the end of the needle 31 of guiding tube 400 with rake 105a's
The corresponding position in middle section, therefore, it is difficult to extract the white blood for the lowest part for remaining in the separated space portion 104 for gradually becoming narrow
Ball.
With reference to the Fig. 8 and Fig. 9 for indicating another embodiment of the present invention, the device of the present embodiment with eccentric manner by being located at
Minor diameter 402 and the notch 402a of the lower side of guiding tube 400 and to the internal face lateral bend of main body tube 100 guide needle 31
End, therefore the white blood cell of the extractable lowest part for remaining in separated space portion 104.
Therefore, the blood for extracting the growth factor rich in blood platelet of the invention detaches and extraction element can pass through one
The separation and concentrate operation that a container and a centrifugal separation processes realization are carried out by the centrifugation of blood, therefore having can
The loss generated during existing transfer is prevented, and improves the effect of the convenience of operation.
Claims (4)
1. a kind of blood separation and extraction element for extracting the growth factor rich in blood platelet, it is characterised in that have：It is main
Body pipe (100) forms the receiving space portion (102) of accommodating blood, in the top shape of the receiving space portion (102) in lower part
At the passage portion (105) with rake (105a) and upper end opening in such a way that internal diameter is narrower than lower part, and it is formed with separation
Spatial portion (104), separated space portion (104) receiving divide via the centrifugation by the blood of the passage portion (105)
From and detach blood separating layer a part；Sliding block (200) is slidably coupled to the receiving space portion
(102), via the passage portion (105) to separated space portion (104) side be forced through it is described centrifugation and detach
The separating layer of blood；And upper cap (300), it is detachably attached to the upper end of the main body tube (100),
Central lower be formed in the main body tube (100) in conjunction with when the engaging portion that is combined with the upper end of the passage portion (105)
(310), and there is storage unit (320), the storage unit (320) is with to the extended side of a side lower part of the engaging portion (310)
Formula is formed, and when the sliding block (200) rise, is flowed into for the Platelet Concentrate (P) in the separating layer of blood and is accommodated the blood
Platelet Concentrate (P) in the separating layer of liquid；And the upper cap (300) forms inlet (300c), first-class in upper surface
Export (300a) and the second outflux (300b), the inlet (300c) to pass through the passage portion (105) for injecting
The first syringe (10) of the blood enters, and first outflux (300a) is housed in the storage for being extracted to outside
The second syringe (20) of Platelet Concentrate (P) in portion (320) enters, and second outflux (300b) to outside for carrying
The third syringe (30) for the white blood cell (W) for being housed in the separated space portion (104) is taken to enter, also, described for extracting
The blood of growth factor rich in blood platelet detaches and extraction element has guiding tube (400), and the guiding tube (400) is attached to
Second outflux (300b) side until the lower part for extending to the separated space portion (104), and guides the third to inject
The needle (31) of device (30)；The guiding tube (400) includes major diameter portion (401), with the side with the major diameter portion (401) bias
The extended minor diameter of formula (402) and the rake for connecting the major diameter portion (401) with minor diameter (402)
(403), in the lower end of the minor diameter (402), the end formed for the needle (31) of the third syringe (30) passes through
Notch (402a).
2. the blood separation and extraction element according to claim 1 for extracting the growth factor rich in blood platelet,
It is characterized in that：In the inlet (300c), the first outflux (300a), the second outflux (300b) in conjunction with for described first
First rubber stopper of the elasticity of needle (needle) entrance of syringe, the second syringe, third syringe (10,20,30), second
Rubber stopper, third rubber stopper (304,302,303).
3. the blood separation and extraction element according to claim 1 for extracting the growth factor rich in blood platelet,
It is characterized in that being also equipped with lower cover (250), the lower cover (250) is attached to the lower part of the main body tube (100), prevents described
Sliding block (200) falls off, and through-hole (255) is formed in center, makes its rising in order to feed to the upside promotion sliding block (200)
Elevating mechanism disengaging.
4. the blood separation and extraction element according to claim 1 for extracting the growth factor rich in blood platelet,
It is characterized in that：The upper cap (300) is also equipped with separating plate (330), separating plate (330) shape in a manner of vertically outstanding
At the bottom surface in the storage unit (320).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020150077608A KR101666451B1 (en) | 2015-06-01 | 2015-06-01 | Seperator and collection apparatus for extracting of Platelet Rich Plasma |
| KR10-2015-0077608 | 2015-06-01 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106176214A CN106176214A (en) | 2016-12-07 |
| CN106176214B true CN106176214B (en) | 2018-09-25 |
Family
ID=57156962
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510566495.9A Active CN106176214B (en) | 2015-06-01 | 2015-09-08 | Blood separation for extracting the growth factor for being rich in blood platelet and extraction element |
Country Status (2)
| Country | Link |
|---|---|
| KR (1) | KR101666451B1 (en) |
| CN (1) | CN106176214B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102228222B1 (en) * | 2017-07-21 | 2021-03-16 | (주)메디퍼스트 | Centrifugal separation case assembly |
| KR102223877B1 (en) * | 2018-08-19 | 2021-03-09 | 주식회사 알엠생명과학 | Centrifugal separation case assembly |
| KR101979382B1 (en) * | 2018-11-30 | 2019-05-17 | (주)레보메드 | Kit for Separating and Concentrating a Body Fluid Cell |
| US11660253B2 (en) | 2019-09-18 | 2023-05-30 | Medisarang Co., Ltd. | Device for extracting platelet rich plasma |
| KR102490576B1 (en) * | 2020-10-19 | 2023-01-19 | 전민용 | Blood separate tube with cell activation part |
| CN116368212A (en) * | 2020-10-19 | 2023-06-30 | 金玟墉 | Blood separation tube with cell activating portion |
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| KR101433293B1 (en) * | 2012-05-03 | 2014-08-22 | 이은혜 | Seperator and collection apparatus for extracting of Platelet Rich Plasma |
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- 2015-06-01 KR KR1020150077608A patent/KR101666451B1/en active IP Right Grant
- 2015-09-08 CN CN201510566495.9A patent/CN106176214B/en active Active
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| KR101110576B1 (en) * | 2009-03-16 | 2012-02-15 | 주식회사 메디사랑 | Seperator and collection vial for platelet rich plasma |
| CN102421362A (en) * | 2009-05-14 | 2012-04-18 | 生物技术研究所I+D有限公司 | Method for preparing at least one compound from blood, and sampling device for use when carrying out said method |
| WO2013058600A2 (en) * | 2011-10-19 | 2013-04-25 | 최득수 | Platelet extraction kit |
| CN103842001A (en) * | 2011-12-29 | 2014-06-04 | 阿梅迪卡株式会社 | Integrated kit for separating blood and concentrating prp and method for extracting prp using same |
| WO2014168409A1 (en) * | 2013-04-11 | 2014-10-16 | (주)굿모닝바이오 | Blood separation container for extracting self-platelet |
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| CN106176214A (en) | 2016-12-07 |
| KR101666451B1 (en) | 2016-10-14 |
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