CN106174525A - 一种防治慢性哮喘的食品及其制备方法 - Google Patents

一种防治慢性哮喘的食品及其制备方法 Download PDF

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CN106174525A
CN106174525A CN201610609044.3A CN201610609044A CN106174525A CN 106174525 A CN106174525 A CN 106174525A CN 201610609044 A CN201610609044 A CN 201610609044A CN 106174525 A CN106174525 A CN 106174525A
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radix
powder
herba
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王兴民
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    • A—HUMAN NECESSITIES
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Abstract

本发明公开了一种防治慢性哮喘的食品及其制备方法，由葛粉、花粉、莲子粉、半枝莲、龙牙草、麻黄、沙参、红花、地龙、元胡、半夏、沙参、陈皮、五味子、草决明、莱菔子、北风草、赤芍、胆南星、蔓荆子、败酱和车前草制备而成，将上述各中药按配比混合加水煎煮成药液，然后加入葛粉、花粉、莲子粉，搅拌均匀，减压浓缩至稠膏，减压干燥，粉碎成粉料，与面粉或米粉结合，制成饼干、面包或发糕。本发明将中药与食品结合，不仅发挥了食品的食疗作用，而且有发挥了中药的治疗以及调理作用，本发明对慢性肺炎具有很好的治疗效果，无毒副作用，安全有效，还可以很好的提高病人的体质。

Description

一种防治慢性哮喘的食品及其制备方法
技术领域
本发明涉及食品领域，具体是一种防治慢性哮喘的食品及其制备方法。
背景技术
慢性哮喘，多由于哮喘急性发作控制不利，或反复呼吸道感染而引起，一年四季皆可发作，不受气候和环境的影响，或虽可用药物控制但缓解期很短，大多合并肺气肿、肺功能减退、缺氧，体格检查时，可见胸部呈桶状。所以，虽然不是急性发作期，但常常感到胸闷、气急、肺部听诊可闻及哮鸣音。慢性哮喘，由于体质较差，抵抗力低下，经常易合并呼吸道感染，出现咳嗽、痰多，呈白色泡沫痰或粘稠痰。由于炎性分泌物阻塞气道，可发展成肺不张，有的发展成支气管扩张，严重者有心肺功能损害，甚至成为肺源性心脏病。虽然市场上已经出现治疗慢性哮喘的中药，但是其治疗的效果并不是很有效，而且也存在一定的副作用，安全性不高。
发明内容
本发明的目的在于提供一种防治慢性哮喘的食品及其制备方法，以解决上述背景技术中提出的问题。
为实现上述目的，本发明提供如下技术方案：
一种防治慢性哮喘的食品，由以下重量份的原料制备而成：葛粉30～36份，花粉12～16份，莲子粉20～24份，半枝莲12～14份，龙牙草16～20份，麻黄10～12份，沙参8～12份，红花16～20份，地龙13～15份，元胡11～13份，半夏9～11份，沙参8～10份，陈皮6～8份，五味子6～8份，草决明10～12份，莱菔子14～16份，北风草6～8份，赤芍11～15份，胆南星10～14份，蔓荆子12～16份，败酱4～6份，车前草8～12份。
作为本发明进一步的方案：所述花粉为松花粉、蜂花粉、玫瑰花粉、菊花粉中的一种。
一种所述的防治慢性哮喘的食品的制备方法，具体步骤如下：
（1）将上述各中药按配比混合，加入各中药总重量10～12倍的去离子水，先武火煮沸5～7min，然后在6～7MPa的压力下加热30～40min，再用文火煎煮2～3h，过滤，冷却至室温，备用；
（2）将葛粉、花粉、莲子粉在常温下依次加入上述合并的过滤液中，边加入边搅拌，至充分混合均匀，在45～50℃下进行减压浓缩至稠膏，减压干燥，粉碎成粉料；
（3）将制备的粉料与面粉或米粉结合，制成饼干、面包或发糕。
与现有技术相比，本发明的有益效果是：
本发明将中药与食品结合，不仅发挥了食品的食疗作用，而且有发挥了中药的治疗以及调理作用，本发明对慢性肺炎具有很好的治疗效果，无毒副作用，安全有效，还可以很好的提高病人的体质。
具体实施方式
下面将结合本发明实施例，对本发明实施例中的技术方案进行清楚、完整地描述，显然，所描述的实施例仅仅是本发明一部分实施例，而不是全部的实施例。基于本发明中的实施例，本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例，都属于本发明保护的范围。
实施例1
防治慢性哮喘的食品，由以下重量份的原料制备而成：葛粉30份，松花粉16份，莲子粉24份，半枝莲12份，龙牙草20份，麻黄10份，沙参12份，红花16份，地龙15份，元胡11份，半夏11份，沙参8份，陈皮8份，五味子6份，草决明12份，莱菔子14份，北风草8份，赤芍11份，胆南星14份，蔓荆子12份，败酱6份，车前草8份。
上述食品的制备步骤如下：
（1）将上述各中药按配比混合，加入各中药总重量10倍的去离子水，先武火煮沸5min，然后在6MPa的压力下加热40min，再用文火煎煮2h，过滤，冷却至室温，备用；
（2）将葛粉、花粉、莲子粉在常温下依次加入上述合并的过滤液中，边加入边搅拌，至充分混合均匀，在45℃下进行减压浓缩至稠膏，减压干燥，粉碎成粉料；
（3）将制备的粉料与面粉或米粉结合，制成饼干。
实施例2
防治慢性哮喘的食品，由以下重量份的原料制备而成：葛粉33份，玫瑰花粉14份，莲子粉22份，半枝莲13份，龙牙草18份，麻黄11份，沙参10份，红花18份，地龙14份，元胡12份，半夏10份，沙参9份，陈皮7份，五味子7份，草决明11份，莱菔子15份，北风草7份，赤芍13份，胆南星12份，蔓荆子14份，败酱5份，车前草10份。
上述食品的制备步骤如下：
（1）将上述各中药按配比混合，加入各中药总重量10～12倍的去离子水，先武火煮沸6min，然后在6.5MPa的压力下加热35min，再用文火煎煮2.5h，过滤，冷却至室温，备用；
（2）将葛粉、花粉、莲子粉在常温下依次加入上述合并的过滤液中，边加入边搅拌，至充分混合均匀，在47.5℃下进行减压浓缩至稠膏，减压干燥，粉碎成粉料；
（3）将制备的粉料与面粉或米粉结合，制成面包。
实施例3
防治慢性哮喘的食品，由以下重量份的原料制备而成：葛粉36份，菊花花粉12份，莲子粉20份，半枝莲14份，龙牙草16份，麻黄12份，沙参8份，红花20份，地龙13份，元胡13份，半夏9份，沙参10份，陈皮6份，五味子8份，草决明10份，莱菔子16份，北风草6份，赤芍15份，胆南星10份，蔓荆子16份，败酱4份，车前草12份。
上述食品的制备步骤如下：
（1）将上述各中药按配比混合，加入各中药总重量12倍的去离子水，先武火煮沸7min，然后在7MPa的压力下加热30min，再用文火煎煮3h，过滤，冷却至室温，备用；
（2）将葛粉、花粉、莲子粉在常温下依次加入上述合并的过滤液中，边加入边搅拌，至充分混合均匀，在50℃下进行减压浓缩至稠膏，减压干燥，粉碎成粉料；
（3）将制备的粉料与面粉或米粉结合，制成发糕。
实施例4 临床试验
1.一般资料
本院2013年至2016年门诊符合诊断标准患者180例，按照就诊次序随机分为治疗组、对照组一和对照组二，治疗组、对照组一、对照组二各60例。治疗组，男30例，女30例，年龄23-69岁；对照组一，男30例，女30例，年龄25-68岁；对照组二，男30例，女30例，年龄24-70岁。三组间年龄、性别及病情等经统计学处理P＞0.05，无显著性差异，具有可比性。
2.诊断标准
西医诊断标准：参照中华医学会呼吸疾病学会诊断标准与《中药新药治疗支气管哮喘临床指导原则》拟定支气管哮喘诊断标准。
中医证候标准：参照《中药新药治疗支气管哮喘的临床研究指导原则》与高等中医药院校统编教材《中医内科学》“哮病”、“喘证”章节中有关内容，拟定“痰癖互阻、肺失宣降”症候标准。
3.治疗方法
治疗组：食用实施例2的食品三个月；
对照组一：现有的中药；
对照组二：舒立迭（含沙美特罗50ug/吸，氟替卡松100ug/吸，产品由葛兰素威康
公司生产）早晚各1次，10天为1个疗程。
4.疗效判断
4. 1肺功能测定
治疗前后一天的呼气峰值流速(PEF)
4. 2疗效判定标准
参照中华医学会制订的《支气管哮喘的定义诊断、严重度分级及疗效判断标准》(修正方案)分为临床控制、显效、好转、无效四级。
（1）临床控制：哮喘的临床症状可完全缓解，即使偶有轻度发作不需药物治疗即可缓解，最大的呼气流量PEF增值＞35%以上，或治疗后PEF达到预计值的80-100%，PEF昼夜波动率<20%。
（2）显效：哮喘发作较治疗前明显改善，PEF值增加25-35%，或治疗后PEF达到预期值的60-79%，PEF昼夜波动率小于20%，仍然需要用激素或支气管舒张剂，但只需既往剂量的1/3。
（3）好转：哮喘症状有所减轻。PEF增值15%-25%，仍需用皮质激素和/或支气管舒张剂，用药剂量不能少于原来的1/2。
（4）无效：临床症状和PEF测定值无改善或加重。
2.结果
2. 1三组PEF值比较
三组治疗前后PEF值比较结果如表1所示:
表1三组PEF值比较
组别 治疗前PEF/s 治疗后PEF/s
治疗组 4.20±0.81 5.86±1.21
对照组一 4.23±0.83 5.01±1.02
对照组二 4.17±0.79 4.35±0.96
注：治疗组治疗前后PEF值比较具有显著差异P＜0. 05，治疗组与对照组一、对照组二治疗后PEF值比较具有显著差异P＜0. 05，具有统计学意义。
2.2治疗组和对照组疗效比较
治疗组和对照组疗效比较结果如表2所示：
表2三组疗效比较
组别 临床控制 显效 好转 无效 总有效率（％）
治疗组 3 15 10 2 93.3
对照组一 6 13 8 3 90
对照组二 5 16 8 1 96.7
由表2可以看出，本发明对慢性哮喘有很好的疗效。
对于本领域技术人员而言，显然本发明不限于上述示范性实施例的细节，而且在不背离本发明的精神或基本特征的情况下，能够以其他的具体形式实现本发明。因此，无论从哪一点来看，均应将实施例看作是示范性的，而且是非限制性的，本发明的范围由所附权利要求而不是上述说明限定，因此旨在将落在权利要求的等同要件的含义和范围内的所有变化囊括在本发明内。

Claims (3)

1.一种防治慢性哮喘的食品，其特征在于，由以下重量份的原料制备而成：葛粉30～36份，花粉12～16份，莲子粉20～24份，半枝莲12～14份，龙牙草16～20份，麻黄10～12份，沙参8～12份，红花16～20份，地龙13～15份，元胡11～13份，半夏9～11份，沙参8～10份，陈皮6～8份，五味子6～8份，草决明10～12份，莱菔子14～16份，北风草6～8份，赤芍11～15份，胆南星10～14份，蔓荆子12～16份，败酱4～6份，车前草8～12份。
2.根据权利要求1所述的防治慢性哮喘的食品，其特征在于，所述花粉为松花粉、蜂花粉、玫瑰花粉、菊花粉中的一种。
3.一种如权利要求1所述的防治慢性哮喘的食品的制备方法，其特征在于，具体步骤如下：
（1）将上述各中药按配比混合，加入各中药总重量10～12倍的去离子水，先武火煮沸5～7min，然后在6～7MPa的压力下加热30～40min，再用文火煎煮2～3h，过滤，冷却至室温，备用；
（2）将葛粉、花粉、莲子粉在常温下依次加入上述合并的过滤液中，边加入边搅拌，至充分混合均匀，在45～50℃下进行减压浓缩至稠膏，减压干燥，粉碎成粉料；
（3）将制备的粉料与面粉或米粉结合，制成饼干、面包或发糕。
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