CN106168573A - A kind of Systems for optical inspection and include the Blood coagulation instrument of this system - Google Patents
A kind of Systems for optical inspection and include the Blood coagulation instrument of this system Download PDFInfo
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- CN106168573A CN106168573A CN201510559480.XA CN201510559480A CN106168573A CN 106168573 A CN106168573 A CN 106168573A CN 201510559480 A CN201510559480 A CN 201510559480A CN 106168573 A CN106168573 A CN 106168573A
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Abstract
The present invention is applicable to technical field of medical instruments, provide a kind of Systems for optical inspection, including light source assembly, optical fiber more than one point, optical fiber fixation kit, specimen holder and photo-detector, light source assembly includes housing and the LED illuminating part of at least one different wave length being arranged at enclosure interior, and it is arranged at the optical filter of each LED illuminating part light emission side, optical fiber more than one point includes single incoming fiber and Duo Gen output optical fibre, exported and pass being optically coupled in input optical fibre of optical filter by LED illuminating part, output optical fibre is fixed by optical fiber fixation kit, the light of its output is focused on photo-detector by the sample on specimen holder.The present invention is not required to rotate wavelength switching by filter wheel, only need to be luminous according to the LED illuminating part that timing controlled switching time is different, compared with the rotation of filter wheel, light switch speed can significantly improve, and then raising detection efficiency, and can increase the service life, this optical system is be applicable to the medical apparatus and instruments of the detection extinction amounts such as Blood coagulation instrument.
Description
Technical field
The invention belongs to technical field of medical instruments, particularly to a kind of Systems for optical inspection and include this system
Blood coagulation instrument.
Background technology
The transmission channels of traditional Blood coagulation instrument mostly uses Halogen light 01 to combine motor and drives optical filtering wheel disc 02
Structure, Halogen light 01 sends wide spectrum optical, and optical filtering wheel disc 02 rotates the optical filter that switching is different, and then output
The light of different wave length, is used for irradiating sample.The test to sample is carried out by gathering the transmission light through sample,
Thus obtain D-Dimer, the data of the projects such as ATIII, FDP.But, this traditional optical system is subject to
Being limited to the rotating speed of optical filtering wheel disc, wavelength switching times is long, and detection efficiency is low, and the service life of Halogen light
Limited, about need to change a Halogen light half a year, therefore also need to regularly replace light source, increase workload,
Cost is the highest.
Summary of the invention
It is an object of the invention to provide a kind of Systems for optical inspection, for Blood coagulation instrument, it is intended to improve medical treatment inspection
Survey efficiency, increase the service life.
The present invention is achieved in that a kind of Systems for optical inspection, including light source assembly, optical fiber more than one point,
Optical fiber fixation kit, specimen holder and photo-detector, described light source assembly includes housing and is arranged at described shell
The LED illuminating part of at least one different wave length in internal portion, and it is arranged at each described LED illuminating part
The optical filter of light emission side, described optical fiber more than one point includes single incoming fiber and Duo Gen output optical fibre, by described
LED illuminating part exports and passes being optically coupled in described input optical fibre of described optical filter, described output optical fibre
Being fixed by described optical fiber fixation kit, the light of described output optical fibre output is gathered by the sample on described specimen holder
Burnt on described photo-detector.
Another object of the present invention is to provide a kind of Blood coagulation instrument, including above-mentioned Systems for optical inspection.
The Systems for optical inspection that the present invention provides, uses novel light source assembly, and it includes at least one wavelength
Different LED illuminating parts, the light emission side at each LED illuminating part is provided with optical filter to obtain predetermined wavelength
With the monochromatic light of bandwidth, this monochromatic light can be directly coupled into single incoming fiber, then by many outputs
Fiber distribution is to different sense channels, and whole system is not required to rotate wavelength switching by filter wheel, only need to press
The LED illuminating part different according to timing controlled switching time is luminous, compared with the rotation of filter wheel, and this wavelength
Switch speed can significantly improve, and then improves detection efficiency;Use LED illuminating part can extend as light source
In service life, it is not required to often change light source, easy to use, low cost.This optical system is applicable to Blood coagulation instrument
In medical apparatus and instruments Deng detection extinction amount.
Accompanying drawing explanation
Fig. 1 is the Systems for optical inspection structural representation of Blood coagulation instrument in prior art;
Fig. 2 is the decomposition texture schematic diagram of the Systems for optical inspection that the embodiment of the present invention provides;
Fig. 3 is the light source assembly structural representation of the Systems for optical inspection that the embodiment of the present invention provides;
Fig. 4 is the optical fiber structure schematic diagram more than a point of the Systems for optical inspection that the embodiment of the present invention provides;
Fig. 5 is the part-structure schematic diagram of the Systems for optical inspection that the embodiment of the present invention provides;
Fig. 6 is the detection index path of the Systems for optical inspection that the embodiment of the present invention provides.
Detailed description of the invention
In order to make the purpose of the present invention, technical scheme and advantage clearer, below in conjunction with accompanying drawing and reality
Execute example, the present invention is further elaborated.Only should be appreciated that specific embodiment described herein
Only in order to explain the present invention, it is not intended to limit the present invention.
Below in conjunction with specific embodiment the present invention implemented and is described in detail:
Refer to Fig. 2 to Fig. 6, the embodiment of the present invention provides a kind of Systems for optical inspection, is mainly used in medical treatment
Detection field, such as Blood coagulation instrument, this system includes successively in optical transmission direction: light source assembly is more than 1, one point
Optical fiber 2, optical fiber fixation kit 3, specimen holder 4 and photo-detector 5, this light source assembly 1 includes housing 11
With the LED illuminating part 12 of at least one different wave length being arranged within housing 11, and it is arranged at each
The optical filter 13 of LED illuminating part 12 light emission side.Such as Fig. 4, more than one point, optical fiber 2 includes single incoming fiber
21 and Duo Gen output optical fibres 22, this input optical fibre 21 and output optical fibre 22 can be with good coupling, by light energy
It is evenly distributed in every output optical fibre 22.The input of the input optical fibre 21 in the present embodiment can be fixed
In the housing 11 of light source assembly 1, and be able to receive that enough light energies, many output optical fibres 22 by
Optical fiber fixation kit 3 is fixed, what LED illuminating part 12 exported and passed optical filter 13 be optically coupled to input
In optical fiber 21, the outfan at input optical fibre 21 uniformly coupled to every output optical fibre 22, every output light
Fine 22 corresponding sense channels.In test process, LED illuminating part 12 ceaselessly alternately flicker, makes not
The light of co-wavelength enters optical fiber, reaches to detect sample, and focuses on photo-detector 5, and photo-detector 5 is right
Optical signal carries out detecting and being converted to the signal of telecommunication, for data analysis to obtain testing result.
The Systems for optical inspection that the embodiment of the present invention provides, uses novel light source assembly 1, and it includes at least
The LED illuminating part 12 that one wavelength is different, the light emission side at each LED illuminating part 12 is provided with optical filter
13 to obtain predetermined wavelength and the monochromatic light of bandwidth, and this monochromatic light can be directly coupled into single incoming fiber
21, then it is assigned to different sense channels by many output optical fibres 22, whole system is not required to pass through filter wheel
Rotate wavelength switching, only need to be luminous, with filter according to the LED illuminating part 12 that timing controlled switching time is different
The rotation of halo is compared, and this wavelength switch speed can significantly improve, and then improves detection efficiency.This light
Learn detecting system and can complete the AD sampling of at least 6 wavelength, position, multiple hole in 1 second.Further, use
LED light source, can increase the service life, and is not required to often change light source, easy to use, low cost.
Further, light source assembly 1 also includes being arranged at the attenuator of the either side of optical filter 13 (in figure not
Show).Specifically, this attenuator can be arranged at the optical filter 13 side near LED illuminating part 12, also
The optical filter 13 side away from LED illuminating part 12 can be arranged on, and in each optical filter 13 side
Attenuator is all set.Preferably, attenuator is fixing with optical filter 13 to be connected, and carries out as a global facility
Assembling.Use attenuator, luminous energy can be carried out appropriateness and weaken, it is to avoid the light that photo-detector 5 receives is too strong
And reach saturated and then impact detection.
With further reference to Fig. 3, the light of optical filter 13 and attenuator output needs to be coupled into input optical fibre 21,
Input optical fibre 21 is fixed in the housing 11 of light source assembly 1, its input towards LED illuminating part 12,
By to LED illuminating part 12 and corresponding optical filter 13 and the position of attenuator and input optical fibre
The position of the input of 21 is reasonably designed, such as, combine the lighting angle of LED illuminating part 12, defeated
Structure and the optical parametric etc. that enter optical fiber 21 configure, or adjust light path by a series of eyeglasses etc. again,
Final guarantee input optical fibre 21 can receive enough light energies.
With further reference to Fig. 2, optical fiber more than one point 2 for light beam is divided into multi beam, such as 3 bundles, 4 bundles,
5 bundles etc..Luminous energy distributes at most root output optical fibre 22 through single incoming fiber 21, through every output optical fibre
Sample is irradiated after 22 outputs.The output optical fibre 22 of this optical fiber 2 more than one point is fixed by optical fiber fixation kit 3,
This optical fiber fixation kit 3 includes a fixed plate 31, and this fixed plate 31 specifically one plate-like piece, in fixed plate
On 31, word order offers the through hole 32 passed for output optical fibre 22, the output termination of output optical fibre 22
221 one by one through through hole 32, and on its outer wall, the position of corresponding through hole 32 is arranged with sealing ring 33, this sealing
Circle 33 is sealed between output optical fibre 22 and through hole 32, can strengthen the fixed effect of output optical fibre 22,
Prevent it from rocking, provide stable illumination for sample.This plate-like piece is additionally provided with other pilot holes, is used for using
Assembly part is fixed in corresponding detection equipment through this pilot hole.
Such as Fig. 2, Fig. 5 and Fig. 6, in the present embodiment, respectively set between each output optical fibre 22 and sample
Having a focus lens group 6, multiple focus lens group can be installed in a lens mounting seat 7, this focusing
Battery of lens 6 is including at least two lens 61.Further, the two panels lens 61 of focus lens group 6 are constituted
Between or the dottle pin circle of employing between any two 62 of multi-disc lens 61 fix lenticular spacing, and each lens 61
Central shaft overlaps.By focus lens group 6, light beam is converged, reduce hot spot and make hot spot uniform, finally gathering
Burnt on photo-detector 5, so can reduce the consumption of sample, and improve the signal to noise ratio of signal.
Such as Fig. 2, in the present embodiment, specimen holder 4 is also fixedly mounted in corresponding detection equipment, and it is opened
Be provided with several for the installation position 41 placing specimen cup 8, each installation position 41 plugs a specimen cup 8,
This installation position 41 and output optical fibre 22 one_to_one corresponding, above-mentioned focus lens group 6 is i.e. positioned at this installation position 41
And between output optical fibre 22.Certainly, this installation position 41 can be and the position, hole of specimen cup 8 form fit,
It can also be the installation folder etc. for sandwiched specimen cup 8.Further, when using position, hole to install, also
One elastomeric element can be set in the edge of each installing hole, when specimen cup 8 inserts installing hole, should
Elastomeric element can be deformed by the sidewall slight squeeze of specimen cup, and then specimen cup is formed lateral pressure, by sample
Cup is stably fixed in installing hole, and so each mechanical arm is more stable when taking cup and put glass, it is to avoid cup
Body rocks.Specifically, this elastomeric element can be spring, is arranged at rim of a cup edge, and its draw direction is vertical
In the short transverse of specimen cup, under naturalness, due to the existence of spring, the rim of a cup width of specimen cup is less than
The diameter of specimen cup, after placing specimen cup, spring slightly stretches and specimen cup is produced lateral pressure.Certainly, should
Elastomeric element can also be other softer, elastic parts being easily deformed.
In the present embodiment, it is also possible to the incident side at photo-detector 5 is provided for filtering the shade of veiling glare
9, enter photo-detector 5 with veiling glares such as the outside visible rays of minimizing and interfere.This shade 9 can be assemblied in
At the incidence window of photo-detector.
In the present embodiment, also include for controlling the controller that different LED illuminating part 12 timesharing is luminous
Part (not shown), to realize being switched fast wavelength.Further, when detecting, generally need
The light energy making multiple sense channels of a certain wavelength is consistent or close, and makes the light energy of different wave length
Consistent or close, corresponding regulation circuit can be set and control device to realize above-mentioned purpose.
The Systems for optical inspection that the present invention provides realizes quick optical wavelength by above-mentioned light source assembly and switches, and carries
High detection efficiency, by arranging focus lens group between output optical fibre and detection sample, can reduce hot spot
Size, is reduced sample consumption and improves signal to noise ratio, being made by the cooperation of above-mentioned optical fiber fixation kit and sealing ring
Output optical fibre to go out light reliable and stable, it is ensured that detection quality.This Systems for optical inspection is applicable to the doctors such as Blood coagulation instrument
Treat apparatus, be mainly used in absorbance measuring, such as D-Dimer, the project such as ATIII, FDP.And then, bag
The Blood coagulation instrument including this Systems for optical inspection is the most within the scope of the present invention.
The foregoing is only presently preferred embodiments of the present invention, not in order to limit the present invention, all at this
Any amendment, equivalent and the improvement etc. made within bright spirit and principle, should be included in the present invention
Protection domain within.
Claims (9)
1. a Systems for optical inspection, it is characterised in that include that light source assembly, optical fiber more than one point, optical fiber are solid
Determining assembly, specimen holder and photo-detector, described light source assembly includes housing and is arranged at described enclosure interior
The LED illuminating part of at least one different wave length, and be arranged at each described LED illuminating part light emission side
Optical filter, described optical fiber more than one point includes single incoming fiber and Duo Gen output optical fibre, described LED sends out
Light part exports and passes being optically coupled in described input optical fibre of described optical filter, and described output optical fibre is by described
Optical fiber fixation kit is fixed, and the light of described output optical fibre output focuses on institute by the sample on described specimen holder
State on photo-detector.
2. Systems for optical inspection as claimed in claim 1, it is characterised in that the input of described input optical fibre
End is fixed in described housing.
3. Systems for optical inspection as claimed in claim 1, it is characterised in that described light source assembly also includes
It is arranged at the attenuator of the either side of described optical filter.
4. Systems for optical inspection as claimed in claim 3, it is characterised in that described attenuator is located at described
The light emission side of optical filter and fixing with described optical filter be connected.
5. Systems for optical inspection as claimed in claim 1, it is characterised in that each described output optical fibre and
A focus lens group it is respectively provided with between described sample.
6. Systems for optical inspection as claimed in claim 1, it is characterised in that described optical fiber fixation kit bag
Include fixed plate, described fixed plate offers the through hole passed for described output optical fibre, described output optical fibre
On outer wall, the position of corresponding described through hole is arranged with the sealing ring for fastening described output optical fibre.
7. Systems for optical inspection as claimed in claim 1, it is characterised in that in entering of described photo-detector
Light side is provided with the shade for filtering veiling glare.
8. Systems for optical inspection as claimed in claim 1, it is characterised in that described Systems for optical inspection is also
Including for controlling the control device that different described LED illuminating part timesharing is luminous.
9. a Blood coagulation instrument, it is characterised in that include the optical detection described in any one of claim 1 to 8
System.
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CN201510559480.XA CN106168573A (en) | 2015-09-06 | 2015-09-06 | A kind of Systems for optical inspection and include the Blood coagulation instrument of this system |
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CN201510559480.XA CN106168573A (en) | 2015-09-06 | 2015-09-06 | A kind of Systems for optical inspection and include the Blood coagulation instrument of this system |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112034568A (en) * | 2020-09-07 | 2020-12-04 | 武汉飞沃科技有限公司 | Stable and adjustable CWDM small module |
CN113994209A (en) * | 2019-07-31 | 2022-01-28 | 深圳迈瑞生物医疗电子股份有限公司 | Sample detection module and sample analyzer |
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CN201014978Y (en) * | 2007-02-12 | 2008-01-30 | 深圳雷杜生命科学股份有限公司 | Optical path device for semi-automatic biochemical analyzer |
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CN203478389U (en) * | 2013-08-23 | 2014-03-12 | 德意电器股份有限公司 | Closed-type spring buckle device |
CN203587598U (en) * | 2013-11-26 | 2014-05-07 | 温州大学 | Handheld smart urine analyzer |
CN104568147A (en) * | 2015-01-07 | 2015-04-29 | 上海科华实验系统有限公司 | Monochromator for microplate readers |
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JPS638537A (en) * | 1986-06-27 | 1988-01-14 | Tosoh Corp | Absorbance measuring apparatus for microplate |
CN201014978Y (en) * | 2007-02-12 | 2008-01-30 | 深圳雷杜生命科学股份有限公司 | Optical path device for semi-automatic biochemical analyzer |
CN201125905Y (en) * | 2007-08-02 | 2008-10-01 | 胜谷实业股份有限公司 | Telescopic positioning apparatus of primary and secondary fitting |
CN202024960U (en) * | 2011-03-30 | 2011-11-02 | 深圳市康立高科技有限公司 | Optical system for flowing type semi-automatic biochemical analyzer |
CN202221407U (en) * | 2011-08-26 | 2012-05-16 | 麦克奥迪实业集团有限公司 | Multispectral microscope |
CN203069505U (en) * | 2013-01-18 | 2013-07-17 | 苏州慧康电子信息科技有限公司 | Multichannel microplate reader |
CN103385695A (en) * | 2013-07-19 | 2013-11-13 | 武汉昊博科技有限公司 | Multi-wavelength liver reserve function detection instrument and ICG (indocyanine green) concentration detection method |
CN203478389U (en) * | 2013-08-23 | 2014-03-12 | 德意电器股份有限公司 | Closed-type spring buckle device |
CN203587598U (en) * | 2013-11-26 | 2014-05-07 | 温州大学 | Handheld smart urine analyzer |
CN104568147A (en) * | 2015-01-07 | 2015-04-29 | 上海科华实验系统有限公司 | Monochromator for microplate readers |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN113994209A (en) * | 2019-07-31 | 2022-01-28 | 深圳迈瑞生物医疗电子股份有限公司 | Sample detection module and sample analyzer |
CN112034568A (en) * | 2020-09-07 | 2020-12-04 | 武汉飞沃科技有限公司 | Stable and adjustable CWDM small module |
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