CN204154641U - Sample analyser and absorbance measuring device thereof - Google Patents

Sample analyser and absorbance measuring device thereof Download PDF

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Publication number
CN204154641U
CN204154641U CN201420581630.8U CN201420581630U CN204154641U CN 204154641 U CN204154641 U CN 204154641U CN 201420581630 U CN201420581630 U CN 201420581630U CN 204154641 U CN204154641 U CN 204154641U
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light
emitting diode
sample
light emitting
exit side
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吴林涛
邱金宏
解传芬
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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Abstract

The utility model discloses a kind of absorbance measuring device, comprising: light source, sample are placed position and be placed on for detecting the sample light electric explorer that sample absorbance on position placed by sample.Wherein, light source comprises: light emitting diode and for providing the driving circuit of drive current to light emitting diode.Because light source adopts light emitting diode and driving circuit thereof to realize.The feature long according to lifetime of LED, can improve the mission life of light source.The utility model also also discloses a kind of sample analyser comprising this absorbance measuring device.

Description

Sample analyser and absorbance measuring device thereof
Technical field
The application relates to a kind of sample analyser, particularly relates to the absorbance measuring device of sample analyser.
Background technology
Biochemical Analyzer and microplate reader are one of visual plants of in-vitro diagnosis inspection, and Biochemical Analyzer main at present and the measuring system of microplate reader all adopt halogen tungsten lamp (as light source), optical filter or grating to coordinate the mode of photodiode.Although this technology is very ripe and be used widely, the halogen tungsten lamp life-span is shorter, is generally 500 ~ 2000h, and namely user needs to replace illuminator, the slightly biased height of illuminator maintenance cost in use for some time.In addition, in the situation that later stage in illuminator life-span possibility existence and stability is poor, measurement result is affected.
Summary of the invention
The application provides a kind of absorbance measuring device, to extend the mission life of absorbance measuring device light source.
According to the first aspect of the application, the application provides a kind of absorbance measuring device, comprising: light source, sample are placed position and be placed on for detecting the sample light electric explorer that sample absorbance on position placed by sample.Wherein, light source comprises: light emitting diode and for providing the driving circuit of drive current to light emitting diode.
Preferably, light emitting diode is multiple light emitting diode or white light emitting diodes with predetermined centre wavelength.
In one embodiment, light source also comprises for collecting and transmitting the optical transmission apparatus of the light that each light emitting diode sends, optical transmission apparatus comprises the light exit side for each lumination of light emitting diode being carried out concentrated outgoing, described light exit side comprises multiple smooth eye point, and the light that each light emitting diode sends is sent by the light eye point corresponding with it.
Light eye point corresponding to Same Wavelength light emitting diode is centrosymmetric around the center of light exit side distribution.
The response that the light eye point that different wave length light emitting diode is corresponding directly records according to sample light electric explorer is arranged to edge to the strong center from light exit side by weak.
Also comprise diaphragm, diaphragm is between the light exit side and sample placement position of light source.
In a kind of instantiation, optical transmission apparatus is All-in-One fibre bundle; The fractionation end of described All-in-One fibre bundle is light incident side, and each fractionation end is near the light emitting diode of its correspondence, and the polymerization end of All-in-One fibre bundle is light exit side, and place position towards sample and arrange, each fibre bundle of light exit side is light eye point.
Optical filter is provided with between the light emitting diode that each fibre bundle of light incident side is corresponding with it.
In a preferred embodiment, when the emission wavelength of light emitting diode is different, the drive current that driving circuit provides to the light emitting diode of different emission wavelength is different.
In another kind of embodiment, light source also comprises light exit side, multiple light-emitting diode arrangement places the side of position at light exit side towards sample, and form light exit side, the light emitting diode of Same Wavelength is centrosymmetric around the center of light exit side distribution, and the response that the light emitting diode of different wave length directly records according to sample light electric explorer is arranged to edge to the strong center from light exit side by weak.
Absorbance measuring device also further comprises: beam splitting mean, reference light detector and information processing and controller; Beam splitting mean is arranged on light exit side and sample and places between position in light path, and the light for being sent by light source is divided into measurement light for irradiating sample and reference light; Reference light detector is arranged in beam splitting mean reference light light path, for collecting reference light; Information processing and controller are connected with driving circuit, sample light electric explorer and reference light detector respectively, receive the electric signal of sample light electric explorer and the output of reference light detector, according to the drive current that described electric signal adjustment driving circuit exports.
In another kind of embodiment, light emitting diode is white light emitting diode, and absorbance measuring device also comprises the light filter with predetermined wavelength, and light filter is arranged on white light emitting diode and sample is placed in the light path between position.
The beneficial effect of the application is: the absorbance measuring device provided according to the application, replace halogen tungsten lamp as the light source of light signal owing to adopting light emitting diode, relative to the technical scheme of halogen tungsten lamp, extend the mission life of illuminator, on the one hand, the replacement frequency of illuminator can be reduced, thus promote the easy degree of user's use; On the other hand, owing to extending the mission life of illuminator, thus the serviceable life of absorbance measuring device can be extended, reduce use cost.In addition, the power of light emitting diode is low, can reduce energy consumption, and it is little to generate heat.This absorbance measuring apparatus structure is simple, is easy to realize.
Accompanying drawing explanation
Fig. 1 is absorbance measuring apparatus structure schematic diagram disclosed in a kind of embodiment of the application;
Fig. 2 is a kind of generation type schematic diagram of the embodiment of the present application light exit side;
Fig. 3 a is a kind of arrangement mode schematic diagram of the embodiment of the present application light exit side;
Fig. 3 b is the another kind of arrangement mode schematic diagram of the embodiment of the present application light exit side;
The light spot shape that Fig. 4 a is formed for arrangement mode shown in the embodiment of the present application Fig. 3 a/large logotype;
The light spot shape that Fig. 4 b is formed for arrangement mode shown in the embodiment of the present application Fig. 3 b/large logotype;
Fig. 5 is light emitting diode radiation intensity comparative examples figure under the embodiment of the present application nominal drive condition;
Fig. 6 is the relative energy utilization factor schematic diagram of the different Exit positions of the embodiment of the present application light signal;
Fig. 7 is absorbance measuring apparatus structure schematic diagram disclosed in the another kind of embodiment of the application.
Embodiment
By reference to the accompanying drawings the present invention is described in further detail below by embodiment.
Embodiment one:
In Biochemical Analyzer and microplate reader equal samples analyser, usually absorbance measuring device is utilized to carry out colorimetric measurement to tested sample, namely utilize light source to provide the illumination of different wave length to penetrate sample successively and place sample on position, the light through sample is detected by photodetector, then the light signal of collection is converted to electric signal transmission and carries out analyzing and processing to analytic system, obtain the absorbance of sample.
Please refer to Fig. 1, Figure 1 shows that absorbance measuring apparatus structure schematic diagram disclosed in the present embodiment.This absorbance measuring device comprises: light source 1, first convergent lens 4, sample place position 2 and sample light electric explorer 3.Sample places position 2 for placing the container accommodating tested sample, in the present embodiment, is described so that cuvette 21 to be placed in sample placement position 2.Light source 1 irradiates the light beam of cuvette 21 for launching, and the first convergent lens 4 is arranged on light source 1 and sample is placed in the light path between position 2, the light that the first convergent lens 4 sends for convergent light source, makes the hot spot that is irradiated on cuvette more concentrated.Sample light electric explorer 3 receives the light after the sample effect in cuvette 21, in the particular embodiment, sample light electric explorer 3 for the light signal of reception being carried out opto-electronic conversion and being sent to information processing and controller, to carry out the spectral analysis process of follow-up sample.In preferred specific embodiment, light source 1, first convergent lens 4, cuvette 21 and sample light electric explorer 3 are arranged along optical axis 10.
In the present embodiment, light source 1 comprises multiple LED, All-in-One fibre bundle 14 and driving circuit (not shown), and each LED is the narrow-band LED with respective centre wavelength.All-in-One fibre bundle 14 is as optical transmission apparatus, comprise the fractionation end 141 being divided into multiple beams of optical fiber bundle and the polymerization end 142 be combined by multiple beams of optical fiber constriction, the fractionation end 141 of All-in-One fibre bundle is light incident side, each LED splitting end its correspondence close, the polymerization end 142 of All-in-One fibre bundle is light exit side, for each lumination of light emitting diode is carried out concentrated outgoing, each fibre bundle of light exit side forms light eye point, light exit side is placed position towards sample and is arranged, to make the light beam irradiation sent to tested sample.
Driving circuit is used for providing drive current to each LED, to control lighting timings and the luminous intensity of diode (LED).In a particular embodiment, multiple light emitting diode can share a driving circuit, also can have independently driving circuit separately, and namely a driving circuit is only for corresponding with it light emitting diode provides drive current.
When detecting, under the control of driving circuit, the LED of different-waveband is lighted in a certain order successively, the light that each LED sends is coupled into independently optical fiber incidence end respectively, and the exit end of these optical fiber is banded in together, form All-in-One fibre bundle as shown in Figure 1.The light that multiple like this LED exports is concentrated to together after All-in-One fibre bundle, cuvette is irradiated to after the first convergent lens 4, and the sample light electric explorer placed by its rear end receive, the signal that sample light electric explorer receives is sent to information processing and controller, for the spectral analysis of sample in cuvette.
Under the control of driving circuit, LED can realize lighting closedown fast, can complete the one-shot measurement of all wavelengths in a short period of time, being on close level, can being applied to the products such as Biochemical Analyzer at a high speed with adopting the photometer of grating beam splitting.When system detects, under the control of information processing and controller, the LED of different-waveband is lighted in a certain order successively, ensure light that a certain single point in time only has a certain wavelength light emitting diodes LED to send through cuvette 21 and receive by sample light electric explorer, namely complete a multispectral data collection after the LED of different wave length lights measurement successively.Information processing and controller also can control LED to be continued to emit beam to cuvette 21, sample light electric explorer 3 continues to carry out multispectral data collection, to complete the time dependent multispectral data record of tested sample, and then carry out corresponding spectral analysis work.
In a preferred embodiment, optical filter 12 is also provided with between the light incident side fibre bundle of each LED and its correspondence, the light that each LED sends arrives fibre bundle through optical filter 12, and optical filter 12 has the wavelength of setting, for the light through setting wavelength.
In this specific embodiment, adopt All-in-One fibre bundle to propagate light, on the one hand, due to the flexibility of optical fiber and the randomness of length, making when designing light emitting diode layout more free, facilitating the design of integral layout.
In another kind of specific embodiment, please refer to Fig. 2, light source also comprises light exit side, such as substrate 13, each LED is arranged in position placed by substrate 13 side towards sample, and form light exit side, the center of substrate 13 is the center of light exit side, in one embodiment, each LED can according to the intensity of respective light signal according to the regular array preset.Substrate 13 is the object that can carry light emitting diode, such as circuit board, and its shape of cross section is preferably circular.
When forming light exit side 11, the arrangement mode of each LED or All-in-One fibre bundle has a variety of.The mode realizing light exit side 11 for All-in-One fibre bundle is described.As shown in Figure 3 a, each circle represents a branch of optical fiber to a kind of arrangement mode of light exit side, and the circle of identical filling represents the fibre bundle of phase co-wavelength, and the feature of the light exit side fibre bundle arrangement mode shown in Fig. 3 a is: the fibre bundle of Same Wavelength concentrates in together.The problem brought like this is: when lighting some LEDs, light exit side 11 only some region has light to penetrate, hot spot when this can cause different LED to be lit on cuvette 21 has difference, thus it is different with position to cause the light of each wavelength to be radiated at the spot size that cuvette 21 is formed.Please refer to Fig. 4 a, suppose that the light exit area of a certain LED be lit is positioned at above the optical axis of the first convergent lens 4, the light that then this LED sends is irradiated to the hot spot A0 that cuvette 21 is formed and is positioned at below the optical axis of the first convergent lens 4 after the first convergent lens 4 acts on, otherwise then hot spot A0 is positioned at above the optical axis of the first convergent lens 4, when other LED be lit, light exit area change time, the position of hot spot A0 also can change thereupon.The hot spot then cuvette formed when there being diaphragm to limit is as shown in A0 ' in Fig. 4 a, when other LED be lit, light exit area change time, the position of hot spot A0 ' and shape all can change thereupon, will have influence on accuracy and the consistance of measurement result.For solving this problem, fiber coupler can be installed additional at the light exit side of All-in-One fibre bundle, but fiber coupler cost is higher, the thousands of unit of general needs.For ensureing that the consistance of the hot spot of different wave length on cuvette 21 also keeps lower cost, disclosed in the present embodiment, a kind of optimal way is: place (such as between the first convergent lens 4 and cuvette 21) between position 2 at light exit side and sample and be placed with diaphragm, diaphragm is used for being blocked by light, thus limit the spot size be radiated on cuvette, the fibre bundle of the light exit side of All-in-One fibre bundle is arranged in such a way, please refer to Fig. 3 b:
The first, light outgoing fibre bundle corresponding to Same Wavelength light emitting diode is centrosymmetric around the center of light exit side 11 distribution.When being centrally located on optical axis of light exit side 11, the light of Same Wavelength is symmetrical centered by optical axis, it is symmetrical centered by optical axis equally that symmetrical light is focused at through the first convergent lens 4 hot spot that cuvette is formed, therefore, this distribution of fibre bundle, the facula position that the light of different wave length can be made to be formed on cuvette is consistent.When being placed with diaphragm between the first convergent lens 4 and cuvette 21, when lighting the LED of a certain wave band, each orientation, the center of light exit side 11 all has light beam to penetrate, and the orientation such as up and down of optical axis all has the light of this wavelength to be irradiated on the first convergent lens 4.Please refer to Fig. 4 b, the light of such as Same Wavelength forms the region of the overlapping formation such as hot spot A1, A2, A3 and A4 after the first convergent lens 4 is assembled.These light are irradiated on cuvette 21 and form hot spot A after diaphragm light hole 20, and size, the shape of hot spot A are subject to the size of diaphragm light hole 20, the impact of shape, thus the spot size that the light of different wave length can be made to be formed on cuvette is consistent.Visible, by this specific configuration and the diaphragm of outgoing fibre bundle, namely can ensure that the light of different wave length is radiated at the position of the hot spot on tested sample after the first convergent lens 4 consistent as far as possible with size, thus improve accuracy and the consistance of measurement.
The second, the response that the light outgoing fibre bundle that different wave length light emitting diode is corresponding directly records according to sample light electric explorer is arranged to edge to the strong center from light exit side 11 by weak.Because the centre wavelength of light emitting diode is different, self radiation intensity of light emitting diode light LED of different wave length also there are differences, sample light electric explorer 3 is not identical for the light emitting diode response of different radiation intensity yet, so may there is a certain wavelength channels intensity when carrying out light-intensity test excessive even beyond the sensing range of detector, and the situation that another wavelength causes signal to noise ratio (S/N ratio) poor because intensity is too small.For making the response of sample light electric explorer to the light emitting diode of different radiation intensity identical, can be realized by any one in wavelength response characteristic three parameters of the radiation intensity of adjustment light emitting diode, light signal energy utilization factor and photodetector.In the present embodiment, the response that fibre bundle directly records according to sample light electric explorer is arranged, the more weak fibre bundle of the response that sample light electric explorer directly records is the closer to the center of light exit side 11, and the stronger fibre bundle of the response that sample light electric explorer directly records is more away from the center of light exit side 11.The response that sample light electric explorer directly records is relevant with the radiation intensity of light emitting diode and the wavelength response characteristic of photodetector, following methods can be adopted to record: under normal circumstances, the light emitting diode of Same Wavelength has identical radiation intensity, the light that light emitting diode sends directly arrives sample light electric explorer without sample, and the value that sample light electric explorer induction light exports is the response that this sample light electric explorer directly records.By the light emitting diode of different wave length, under same test condition, (such as adopt same photodetector, test position are identical, temperature is identical, drive current is identical, through same light path etc.), through the detection of sample light electric explorer, thus can draw the response that the sample light electric explorer of each wavelength light emitting diodes directly records.If the response that the sample light electric explorer of the light emitting diode of certain wavelength directly records is smaller, then by the light-emitting diode arrangement of this wavelength at inner ring, if the response that the sample light electric explorer of the light emitting diode of certain wavelength directly records is larger, then by the light-emitting diode arrangement of this wavelength in outer ring, as shown in Figure 3 b.When being centrally located on optical axis of light exit side 11, light more departs from optical axis, and utilization factor is less, and light is the closer to optical axis, and utilization factor is larger, and Fig. 6 is the relative energy utilization factor of the different Exit positions of light signal, and distance light exit side center is far away, and utilization factor is less.Thus, also the response of equalization photodetector can be carried out by the position adjusting light exit side, if the response that photodetector directly records is smaller, then the distance of light exit side and optical axis is adjusted near, if the response that photodetector directly records is larger, then the distance of light exit side and optical axis is adjusted far away.Figure 5 shows that response comparison diagram before and after the arrangement that sample light electric explorer records under nominal drive condition of different wave length light emitting diode, the light emitting diode of visible different wave length is after arranging according to the present embodiment mode, and the response of sample light electric explorer more reaches unanimity.Certainly, the response of equalization photodetector also can be carried out by the wavelength response characteristic selecting photodetector.Under normal circumstances, determine light emitting diode and photodetector, the radiation intensity of light emitting diode and the response characteristic of detector just determine, and want the response that equalization sample light electric explorer directly records, and need the capacity usage ratio adjusting light signal.
Certainly, in other embodiments, also each light exit side order of All-in-One fibre bundle can be upset completely, random arrangement, also the consistance of hot spot on cuvette can be realized, but which effect when fiber cores silk negligible amounts is poor, and cannot realize the adjustment of different wave length light radiation intensity.
In a particular embodiment, also light exit side 11 is arranged on the focal position of the first convergent lens 4, such as, light exit side 11 is arranged perpendicular to optical axis 10, and make it be centrally located at the focal position of the first convergent lens 4.This set coordinates with the arrangement mode of the light exit side shown in Fig. 3 b again, and the illumination further improving different wave length is mapped to the consistance of hot spot on cuvette.
According to content disclosed in the present application, those skilled in the art only can also adopt one of them aspect of above-mentioned arrangement mode, and reach corresponding effect, such as only make the light eye point of Same Wavelength to be centrosymmetric around the center of light exit side distribution, or the response only making the light eye point of different wave length directly record according to sample light electric explorer is arranged to edge to the strong center from light exit side by weak.When not needing to ensure that on cuvette, hot spot is in the same size, also diaphragm can not be needed.
It should be noted that, realize in the embodiment of light exit side for substrate, the arrangement mode of above-mentioned light emitting diode optical fiber bundle also can be adopted to arrange on substrate light emitting diode.In like manner, the position of substrate also can be set with reference to the position of above-mentioned light exit side 11, though substrate be centrally located on optical axis, be preferably placed at the focal position of the first convergent lens 4.
In other specific embodiment, other devices can also be adopted as optical transmission apparatus, the light that each light emitting diode is sent is concentrated by the light eye point corresponding with it and is sent.
Collection can be received by sample light electric explorer 3 with effectively assembling to make the light after cuvette 21 transmission, in a kind of specific embodiment, absorbance measuring device can further include the second convergent lens 5, second convergent lens 5 is arranged on sample and places between position 2 and sample light electric explorer 3, when laying the second convergent lens 5, the optical axis of the second convergent lens 5 should overlap with optical axis 10.Photodetector 3 is preferably placed in the focus of lens 5.
Embodiment two:
Because the luminous intensity of LED is also relevant with drive current, drive current is larger, luminous intensity is larger, therefore in a certain embodiment, also design according to the drive current of the radiation intensity of light emitting diode to light emitting diode on the basis of above-described embodiment, under normal circumstances, the light emitting diode of selected same emission wavelength has identical radiation intensity, therefore driving circuit export drive current based on driven light emitting diode emission wavelength and determine, make the light emitting diode of each wavelength, a corresponding drive current, driving circuit provides different drive currents to the light emitting diode of different emission wavelength.Theoretically, when suitably improving for different wave length respectively according to the difference of its radiation intensity or reduce its drive current, the relative radiant intensity of the different wave length light emitting diode that detector responds can reach completely the same, thus avoids the different problem of response that detector causes because LED radiation intensity is different.
When multiple light emitting diode shares a driving circuit, information processing and controller according to the lighting timings of each light emitting diode, can control driving circuit and provide the drive current corresponding with the emission wavelength of this light emitting diode to each light emitting diode.
When having multiple driving circuit, can set the drive current of each driving circuit output according to the emission wavelength of light emitting diode, the output terminal of each driving circuit is coupled to the light emitting diode of Same Wavelength.
Embodiment three:
The radiation intensity of LED has the feature with temperature, curent change, and LED is also unstable in its radiation intensity of the initial stage of lighting simultaneously, in order to ensure stability and the Quick Measurement of system, needing to add reference light and compensating and correcting.Please refer to Fig. 7, absorbance measuring device disclosed in the present embodiment also comprises beam splitting mean 61 and reference light detector 62, beam splitting mean 61 is arranged on light exit side 11 and sample and places between position in light path, light for being sent by light source is divided into transmitted light and reflected light, for comprising in the embodiment of the first convergent lens 4, beam splitting mean 61 is preferably arranged on the first convergent lens 4 and sample is placed between position 2.In a particular embodiment, beam splitting mean 61 can be spectroscope, also referred to as dichroscope.Reference light detector 62 is arranged in beam splitting mean reflected light light path, for collecting the light through beam splitting mean reflection.As shown in Figure 7, place between position 2 at the first convergent lens 4 and sample and place a dichroscope, received by sample light electric explorer 3 after the light small part of the first convergent lens 4 outgoing to be reflexed to most of light therethrough dichroscope of reference light detector 62, first convergent lens 4 outgoing and cuvette 21 by dichroscope.Information processing and controller are connected with sample light electric explorer 3 and reference light detector 62 respectively, receive the electric signal of sample light electric explorer 3 and reference light detector 62 output, when detecting according to the change of signal on reference light detector 62, sample measurement is revised, thus the impact of LED change in radiation intensity on measurement result can be eliminated, improve the Stability and veracity of spectral measurement, improve the performance of measurement mechanism.
In other specific embodiment, light emitting diode can be white light emitting diode, absorbance measuring device also comprises the light filter with predetermined wavelength, and light filter is arranged on white light emitting diode and sample is placed in the light path between position, and light filter can be optical filter or grating.White light emitting diode can have one or more, when one or more white light emitting diode concentrates in together outgoing, filter design can be become a rotating disk, the card of rotating disk offers multiple through hole, the optical filter of predetermined wavelength is installed in each through hole, different optical filters has different wavelength, runner is by rotating and/or translation, the optical filter of required wavelength is rotated in light path, the light that light emitting diode sends can obtain the light of required wavelength after optical filter, and makes the illumination of required wavelength be mapped to cuvette.But when having multiple white light emitting diode, light filter is to there being multiple optical filter, through Systematical control, multiple white light emitting diode can be made to light successively according to the order of setting, and the light that each light emitting diode sends is irradiated to cuvette after the optical filter of himself correspondence.
Absorbance measuring apparatus structure disclosed in the embodiment of the present application is simple, and cost is low; Adopt light emitting diode to substitute traditional halogen tungsten lamp and light signal is provided, extend the serviceable life of absorbance measuring device.
Above content is in conjunction with concrete embodiment further description made for the present invention, can not assert that specific embodiment of the invention is confined to these explanations.For general technical staff of the technical field of the invention, without departing from the inventive concept of the premise, some simple deduction or replace can also be made.

Claims (15)

1. an absorbance measuring device, comprise light source (1), position (2) placed by sample and be placed on for detecting the sample light electric explorer (3) that sample absorbance on position placed by sample, it is characterized in that, described light source (1) comprising:
Light emitting diode (LED);
For providing the driving circuit of drive current to light emitting diode (LED).
2. absorbance measuring device as claimed in claim 1, it is characterized in that, described light emitting diode is multiple light emitting diodes with predetermined centre wavelength.
3. absorbance measuring device as claimed in claim 2, it is characterized in that, described light source (1) also comprises light exit side, described multiple light emitting diode (LED) is arranged in described light exit side and places the side of position towards sample, and the light emitting diode of Same Wavelength is centrosymmetric around the center of light exit side distribution.
4. absorbance measuring device as claimed in claim 3, is characterized in that, the response that the light emitting diode of different wave length directly records according to sample light electric explorer is arranged to edge to the strong center from light exit side by weak.
5. absorbance measuring device as claimed in claim 1, it is characterized in that, described light emitting diode is white light emitting diode.
6. the absorbance measuring device as described in claim 2 or 5, it is characterized in that, described light source (1) also comprises for collecting and transmitting the optical transmission apparatus of the light that each light emitting diode sends, optical transmission apparatus comprises the light exit side for each lumination of light emitting diode being carried out concentrated outgoing, described light exit side comprises multiple smooth eye point, and the light that each light emitting diode sends is sent by the light eye point corresponding with it.
7. absorbance measuring device as claimed in claim 6, is characterized in that, light eye point corresponding to Same Wavelength light emitting diode is centrosymmetric around the center of light exit side distribution.
8. absorbance measuring device as claimed in claim 7, is characterized in that, the response that the light eye point that different wave length light emitting diode is corresponding directly records according to sample light electric explorer is arranged to edge to the strong center from light exit side by weak.
9. absorbance measuring device as claimed in claim 7, is characterized in that, also comprise diaphragm, and described diaphragm is positioned between the light exit side of light source (1) and sample placement position (2).
10. absorbance measuring device as claimed in claim 6, it is characterized in that, described optical transmission apparatus is All-in-One fibre bundle (14); The fractionation end of described All-in-One fibre bundle is light incident side, and each fractionation end is near the light emitting diode of its correspondence, and the polymerization end of All-in-One fibre bundle is light exit side, and place position towards sample and arrange, each fibre bundle of light exit side is light eye point.
11. absorbance measuring devices as claimed in claim 10, is characterized in that, also comprise the optical filter between each fibre bundle of being located at light incident side respectively light emitting diode corresponding with it.
12. absorbance measuring devices as claimed in claim 2, is characterized in that, the drive current that described driving circuit provides to the light emitting diode of different emission wavelength is different.
13. absorbance measuring devices as claimed in claim 12, it is characterized in that there is multiple driving circuit, the output terminal of each driving circuit is coupled to the light emitting diode of Same Wavelength.
14., as the absorbance measuring device in claim 1-4 as described in any one, characterized by further comprising:
Beam splitting mean (61), is arranged on light exit side and sample and places between position in light path, and the light for being sent by light source is divided into measurement light for irradiating sample and reference light;
Reference light detector (62), is arranged in beam splitting mean reference light light path, for collecting reference light;
Information processing and controller, be connected with sample light electric explorer (3) and reference light detector (62), the electric signal that reception sample light electric explorer (3) and reference light detector (62) export, according to described electric signal correction sample measurement.
15. 1 kinds of sample analysers, comprise as the absorbance measuring device in claim 1-14 as described in any one.
CN201420581630.8U 2014-10-09 2014-10-09 Sample analyser and absorbance measuring device thereof Active CN204154641U (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105572058A (en) * 2014-10-09 2016-05-11 深圳迈瑞生物医疗电子股份有限公司 Sample analyzer and absorbance measurement device thereof
CN113218623A (en) * 2020-02-04 2021-08-06 均豪精密工业股份有限公司 Optical detection system

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105572058A (en) * 2014-10-09 2016-05-11 深圳迈瑞生物医疗电子股份有限公司 Sample analyzer and absorbance measurement device thereof
CN105572058B (en) * 2014-10-09 2024-01-02 深圳迈瑞生物医疗电子股份有限公司 Sample analyzer and absorbance measuring device thereof
CN113218623A (en) * 2020-02-04 2021-08-06 均豪精密工业股份有限公司 Optical detection system

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Assignee: Shenzhen Mindray Animal Medical Technology Co.,Ltd.

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Denomination of utility model: Sample analyzer and absorbance measuring device

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Record date: 20220804