CN106139061A - A kind of Chinese medicine composition of the nocturnal fretfulness in infants treating Deficiency and coldness of spleen and stomach - Google Patents

Abstract

The invention belongs to tcm field, particularly disclose the Chinese medicine composition of a kind of nocturnal fretfulness in infants treating Deficiency and coldness of spleen and stomach, with the Radix Linderae, Rhizoma Alpiniae Officinarum, Rhizoma Cyperi part, Pericarpium Citri Reticulatae, the Radix Aucklandiae, Radix Platycodonis, Radix Glycyrrhizae, the Radix Paeoniae Alba, Rhizoma Zingiberis Preparatum, Fructus Amomi, the Rhizoma Atractylodis Macrocephalae, Poria, Medulla Junci, Bombyx Batryticatus, Cinnabaris, Radix Puerariae, Periostracum Cicadae, Herba Menthae, Concha Margaritifera, Radix Polygalae, Fructus Gardeniae, Folium Bambusae, Ramulus Uncariae Cum Uncis, Semen Sojae Preparatum as raw material, formulated according to certain weight proportion.The present invention prepares simply, good absorbing effect, and duration of efficacy is long, evident in efficacy, has no side effect, and safety is high, and production cost is low, and beneficially sufferer alleviates condition of illness in time.

Description

A kind of Chinese medicine composition of the nocturnal fretfulness in infants treating Deficiency and coldness of spleen and stomach

Technical field

The invention belongs to tcm field, relate to the Chinese medicine composition of a kind of nocturnal fretfulness in infants treating Deficiency and coldness of spleen and stomach.

Background technology

Nascent child cry is usually physiological phenomenon；If daytime is quiet, usually crys at nightfall, the most just fall asleep, slightly startle and just cry endlessly, cry then for morbid state the most whole night, how because of caused by Deficiency and coldness of spleen and stomach.Face card must detailed medical history-taking, go through physique, be aided with relevant lab testing if desired, that gets rid of that the diseases such as fever caused by exogenous pathogens, aphtha, intussusception, colic of cold type cause crys, in order to avoid affecting the infant state of an illness adversely.

The Clinical symptoms of the nocturnal fretfulness in infants of Deficiency and coldness of spleen and stomach is: children's often occurs that sob is humble, sleep happiness and curls, abdomen happiness touch by, extremities being not warm, suck the breast unable, complexion is bluish white, coolness of extremities, happiness is lain prostrate, and abdominal part is sent out cool, and lower limb of bending over to curl up is cry and screamed, anorexia, big loose stool is thin, clear urine in large amounts, and words are light red, pale tongue with white fur, light red superficial venule of the index finger.

At present, suffers from the children's of the night cry of Deficiency and coldness of spleen and stomach, hospitalization or say supertition at home, the most to no effect.People often can only allow " night cry youth " to wait until, and daybreak, doctor trained in Western medicine a shot in the locker are to use opioid therapy.Along with the raising of people's living standard, mostly the most nowadays being only child, it is looked after to have and adds by father and mother, and family several generations can be caused worried.

Summary of the invention

Technical problem

In order to overcome above deficiency, the present invention provides the Chinese medicine composition of a kind of nocturnal fretfulness in infants treating Deficiency and coldness of spleen and stomach.

Solution

The Chinese medicine composition of a kind of nocturnal fretfulness in infants treating Deficiency and coldness of spleen and stomach, is made up of the activated feedstock of following parts by weight:

The Radix Linderae 4 ~ 12 parts, Rhizoma Alpiniae Officinarum 6 ~ 12 parts, Rhizoma Cyperi 4 ~ 9 parts, Pericarpium Citri Reticulatae 3 ~ 6 parts,

The Radix Aucklandiae 4 ~ 12 parts, Radix Platycodonis 2 ~ 6 parts, 2 ~ 10 parts of Radix Glycyrrhizae, the Radix Paeoniae Alba 2 ~ 8 parts,

Rhizoma Zingiberis Preparatum 2 ~ 10 parts, Fructus Amomi 2 ~ 6 parts, the Rhizoma Atractylodis Macrocephalae 2 ~ 6 parts, 2 ~ 6 parts of Poria,

Medulla Junci 1 ~ 6 part, Bombyx Batryticatus 3 ~ 12 parts, 0.3 ~ 1 part of Cinnabaris, Radix Puerariae 6 ~ 12 parts,

Periostracum Cicadae 2 ~ 6 parts, Herba Menthae 2 ~ 6 parts, Concha Margaritifera 9 ~ 15 parts, Radix Polygalae 3 ~ 12 parts,

Fructus Gardeniae 4 ~ 10 parts, 6 ~ 12 parts of Folium Bambusae, Ramulus Uncariae Cum Uncis 6 ~ 12 parts, Semen Sojae Preparatum 6 ~ 12 parts.

A kind of Chinese medicine composition of the nocturnal fretfulness in infants treating Deficiency and coldness of spleen and stomach, the weight proportion of its preferred each activated feedstock is:

The Radix Linderae 8 parts, Rhizoma Alpiniae Officinarum 9 parts, Rhizoma Cyperi 6 parts, Pericarpium Citri Reticulatae 5 parts,

The Radix Aucklandiae 5 parts, Radix Platycodonis 4 parts, 3 parts of Radix Glycyrrhizae, the Radix Paeoniae Alba 6 parts,

Rhizoma Zingiberis Preparatum 9 parts, Fructus Amomi 6 parts, the Rhizoma Atractylodis Macrocephalae 3 parts, 3 parts of Poria,

Medulla Junci 2 parts, Bombyx Batryticatus 6 parts, 0.6 part of Cinnabaris, Radix Puerariae 9 parts,

Periostracum Cicadae 4 parts, Herba Menthae 4 parts, Concha Margaritifera 12 parts, Radix Polygalae 6 parts,

Fructus Gardeniae 7 parts, 9 parts of Folium Bambusae, Ramulus Uncariae Cum Uncis 9 parts, Semen Sojae Preparatum 9 parts.

Instructions of taking:Chinese medicine of the present invention is decoction, cold water is accompanied to soak above Chinese medicine 35 minutes with 5, after firepower elder generation literary composition, force is decocted 15 minutes, twice extracting juice 10 30ml, every day 1 dose (10ml, 15ml in 6 months in 1 month, 20ml in 12 months, more than 12 months 30ml), it is taken in small doses at short intervals several times, within 5 days, is 1 course for the treatment of.

Pathogen and pathology of tcm: the nocturnal fretfulness in infants is the most on the books in more than 1,000 years front TCM Document.Owing to children's's internal organs are tender and lovely, manner cowardice, if children's nurses improper: infant has eaten supercool thing or cold breast milk (mother's excess eats raw food, iced food), have a cold outside or and attack tripe abdomen and feel the cold impairment of the spleen, make inward invasion of pathogenic cold or mother's ferritic deficiency and coldness, addiction to uncooked and cold food time conceived, it is hot and suffocating that congenital defect can result in the spleen-cold syndrome stagnation of QI, easily forms simulataneous insufficiency and excessive；In a word, cold then pain and crow, heat is then tired and crows, frightened then refreshing uneasiness and crow, the Etiological pathogenesis into primary disease of trembling with fear.

The pharmaceutical characteristic of each activated feedstock of the present invention is:

The Radix Linderae: promoting the circulation of QI to relieve pain, warming kidney for dispelling cold.Cure mainly fullness in the chest and hypochondrium vexed, abdominal distention, headache, colic of cold type pain, dysmenorrhea and puerperal abdonimal pain, frequent micturition, the enuresis.Medulla Junci: relieving stranguria by diuresis, clearing heart fire.Cure mainly pyretic stranguria, edema, dysuria, jaundice due to damp-heat, dysphoria and insomnia, the nocturnal fretfulness in infants, sore throat, aphtha of the mouth and tongue.Bombyx Batryticatus: expelling wind and relieving convulsion, dissipating phlegm and resolving masses, resolving toxin and disinhibiting the throat.Cure mainly infantile convulsion to twitch, apoplexy facial hemiparalysis, migraine and general headache, laryngopharynx swelling and pain, scrofula, mumps, rubella, sore.

Cinnabaris: arresting convulsion of calming the nerves, improving eyesight, removing toxic substances.Cure mainly vexed, insomnia, palpitation with fear, demented, blurred vision, sore swollen toxin.Radix Puerariae: expelling pathogenic factors from muscles is delivered, promoting the production of body fluid to quench thirst, yang invigorating antidiarrheal.Cure mainly fever caused by exogenous pathogens, rigidity pain on the head and nape, measles from the beginning of, rash goes out smooth, and epidemic febrile disease is thirsty, diabetes, has loose bowels, dysentery.Periostracum Cicadae: dispelling wind-heat, rash sore-throat relieving, expelling wind and relieving convulsion.Cure mainly anemopyretic cold, laryngopharynx swelling and pain, hoarseness of coughing, measles without adequate eruption, rubella pruritus, cataract, infantile convulsion tic, tetanus.Herba Menthae: dispelling wind-heat, the clear profit head, sore-throat relieving, rash, dispersing the stagnated live-QI to relieve the stagnation of QI.Cure mainly wind heat to characterize, conjunctival congestion of having a headache, laryngopharynx swelling and pain, measles without adequate eruption, rubella pruritus, hypochondriac pain due to stagnation of liverQI.

Concha Margaritifera: suppressing the hyperactive liver and subsiding YANG, arresting convulsion of calming the nerves, liver heat removing and eyesight improving.Cure mainly headache dizziness, palpitation and insomnia, demented infantile convulsion, liver-heat conjunctival congestion, pterygium.Radix Polygalae: mind tranquilizing and the heart calming, eliminates the phlegm and has one's ideas straightened out, removing toxic substances and promoting subsidence of swelling.Curing mainly irritability, palpitation with fear is had a sleepless night, forgetful, infantile convulsion, cough with copious phlegm, carbuncle carbuncle on the back, breast swell and pain.Fructus Gardeniae: pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Cure mainly calentura vexed, liver-fire conjunctival congestion, headache, jaundice due to damp-heat, stranguria, spit blood, epistaxis, dysentery, hematuria, aphtha of the mouth and tongue.Folium Bambusae: clearing heat and relieving fidgetness, promotes the production of body fluid, diuresis.Curing mainly calentura excessive thirst, pediatric epilepsy scared, cough with dyspnea tells nosebleed, oliguria with reddish urine, the raw skin ulcer of erosion of the oral mucosa.Ramulus Uncariae Cum Uncis: relieving spasm by subduing liver-wind, heat clearing away suppressing the hyperactive liver.Curing mainly infantile convulsion, night cry, intenseness of heat wind symptom, eclamposia, dizziness due to hyperactivity of liver-YANG, liver-fire distending pain in the head, and cold headache high fever, epistaxis is more than.Semen Sojae Preparatum: expelling pathogenic factors from muscles is delivered, declares strongly fragrant relieving restlessness.Curing mainly diseases caused by exogenous pathogenic factor exterior syndrome, cold and heat are had a headache, vexed, uncomfortable in chest, heartburn sleeplessness.

The Radix Linderae, Rhizoma Alpiniae Officinarum, Rhizoma Zingiberis Preparatum warming spleen and stomach for dispelling cold, warming middle-JIAO and strengthening the spleen, Fructus Amomi, Pericarpium Citri Reticulatae, the Radix Aucklandiae, Rhizoma Cyperi promoting the circulation of QI to relieve pain；The Radix Paeoniae Alba, Radix Glycyrrhizae relieving spasm to stop pain, Radix Platycodonis medicine carrying is up, harmonizing the functional activities of vital QI, the Rhizoma Atractylodis Macrocephalae, Poria invigorating the spleen and benefiting QI；Periostracum Cicadae, Ramulus Uncariae Cum Uncis are dispeled the wind relieving convulsion.Double join Medulla Junci, Folium Bambusae is mainly used in clearing heart fire, mind tranquilizing and the heart calming；Double adding, joins Bombyx Batryticatus, Periostracum Cicadae, Herba Menthae, Radix Polygalae, be mainly used in expellingging wind and relieving convulsion, dissipating phlegm and resolving masses, resolving toxin and disinhibiting the throat, dispelling wind-heat；The most double join Radix Puerariae, the Radix Linderae, Semen Sojae Preparatum, deliver for expelling pathogenic factors from muscles, promoting the production of body fluid to quench thirst, promoting the circulation of QI to relieve pain, warming kidney for dispelling cold；The most double join Cinnabaris, Concha Margaritifera, Fructus Gardeniae, Ramulus Uncariae Cum Uncis, for suppressing the hyperactive liver and subsiding YANG, calm the nerves arresting convulsion, liver heat removing and eyesight improving.

Invention beneficial effect

Invigorating spleen and kidney of the present invention, warming the spleen cold expelling, tranquilizing the mind is the rule for the treatment of, and the combination of multiple medical material is collaborative, is mainly used in the nocturnal fretfulness in infants of Deficiency and coldness of spleen and stomach, also has significant preventive and therapeutic effect to the nocturnal fretfulness in infants.Invention medical material is pollution-free, cheap for this, take conveniently, make simple, it is particular enable to adapt to live in the people away from small towns, outlying village use, solves locality and lack the problem that medical condition is cured the disease, and hospitalization is invalid or " difficult problem " that cannot treat at home.

Detailed description of the invention

Embodiment 1

Take the Radix Linderae 6 parts, Rhizoma Alpiniae Officinarum 6 parts, Rhizoma Cyperi 3 parts, Pericarpium Citri Reticulatae 3 parts, the Radix Aucklandiae 3 parts, Radix Platycodonis 4 parts, 3 parts of Radix Glycyrrhizae, the Radix Paeoniae Alba 6 parts, Rhizoma Zingiberis Preparatum 3 parts, Fructus Amomi 6 parts, the Rhizoma Atractylodis Macrocephalae 3 parts, 3 parts of Poria, Medulla Junci 2 parts, Bombyx Batryticatus 3 parts, 0.6 part of Cinnabaris, Radix Puerariae 3 parts, Periostracum Cicadae 4 parts, Herba Menthae 4 parts, Concha Margaritifera 12 parts, Radix Polygalae 6 parts, Fructus Gardeniae 7 parts, 9 parts of Folium Bambusae, Ramulus Uncariae Cum Uncis 3 parts, Semen Sojae Preparatum 3 parts.Usage and dosage: accompanying cold water to soak above Chinese medicine 35 minutes with 5, after firepower elder generation literary composition, force is decocted 15 minutes, twice extracting juice 10 30ml, every day 1 dose (10ml, 15ml in 6 months, 20ml in 12 months in 1 month, more than 12 months 30ml), it is taken in small doses at short intervals several times, within 5 days, is 1 course for the treatment of.

Embodiment 2

Take the Radix Linderae 8 parts, Rhizoma Alpiniae Officinarum 9 parts, Rhizoma Cyperi 6 parts, Pericarpium Citri Reticulatae 5 parts, the Radix Aucklandiae 5 parts, Radix Platycodonis 4 parts, 3 parts of Radix Glycyrrhizae, the Radix Paeoniae Alba 6 parts, Rhizoma Zingiberis Preparatum 9 parts, Fructus Amomi 6 parts, the Rhizoma Atractylodis Macrocephalae 3 parts, 3 parts of Poria, Medulla Junci 2 parts, Bombyx Batryticatus 6 parts, 0.6 part of Cinnabaris, Radix Puerariae 9 parts, Periostracum Cicadae 4 parts, Herba Menthae 4 parts, Concha Margaritifera 12 parts, Radix Polygalae 6 parts, Fructus Gardeniae 7 parts, 9 parts of Folium Bambusae, Ramulus Uncariae Cum Uncis 9 parts, Semen Sojae Preparatum 9 parts.Usage and dosage: accompanying cold water to soak above Chinese medicine 35 minutes with 5, after firepower elder generation literary composition, force is decocted 15 minutes, twice extracting juice 10 30ml, every day 1 dose (10ml, 15ml in 6 months, 20ml in 12 months in 1 month, more than 12 months 30ml), it is taken in small doses at short intervals several times, within 5 days, is 1 course for the treatment of.

Embodiment 3

Take the Radix Linderae 9 parts, Rhizoma Alpiniae Officinarum 12 parts, Rhizoma Cyperi 12 parts, Pericarpium Citri Reticulatae 5 parts, the Radix Aucklandiae 5 parts, Radix Platycodonis 4 parts, 3 parts of Radix Glycyrrhizae, the Radix Paeoniae Alba 6 parts, Rhizoma Zingiberis Preparatum 12 parts, Fructus Amomi 6 parts, the Rhizoma Atractylodis Macrocephalae 12 parts, 12 parts of Poria, Medulla Junci 2 parts, Bombyx Batryticatus 6 parts, 0.6 part of Cinnabaris, Radix Puerariae 9 parts, Periostracum Cicadae 4 parts, Herba Menthae 4 parts, Concha Margaritifera 12 parts, Radix Polygalae 6 parts, Fructus Gardeniae 7 parts, 9 parts of Folium Bambusae, Ramulus Uncariae Cum Uncis 9 parts, Semen Sojae Preparatum 9 parts.Usage and dosage: accompanying cold water to soak above Chinese medicine 35 minutes with 5, after firepower elder generation literary composition, force is decocted 15 minutes, twice extracting juice 10 30ml, every day 1 dose (10ml, 15ml in 6 months, 20ml in 12 months in 1 month, more than 12 months 30ml), it is taken in small doses at short intervals several times, within 5 days, is 1 course for the treatment of.

Clinical data

1, physical data

200 examples are all outpatient, are randomly divided into treatment group and matched group.Treatment group 100 example: wherein, man, 59 examples, female 41 example；The month 18 at age 0-3 example, April-July 62 example, August-December 16 example, other: 4 examples；Matched group 100 example: the maleest 49 examples, female 51 example；The month 9 at age 0-3 example, example in April-July 17, August-December 71 example, other: 3 examples；The basic conditions such as the age of two groups of patients, sex, the course of disease there was no significant difference, and has comparability.

2, method

2.1 Therapeutic Method:

Treatment group is administered orally Chinese medicine composition decoction of the present invention, every day potion.Matched group: calcium gluconate day takes liquid, 2/day, vitamin A And D drops 1/day, take day.Two groups of cases were all 1 course for the treatment of with 1 week, and continuous 2 courses for the treatment of judge curative effect；

2.2 criterions of therapeutical effect:

Recovery from illness: sleep is normal, food receives increases, and complexion is the most ruddy, and stool is normally；

Taking a turn for the better: sleep improvement, cry and scream night and alleviate, increase received by food；

Invalid: night cry has no and is clearly better or increases the weight of, inappetence；

2.3 statistical analysiss, use SPSS13 statistical analysis software to be analyzed, and enumeration data uses x2 to analyze, with the standard of P ＜ 0.05 significant difference the most.

3, result

3.1 efficacy result

Treatment group comparitive study the results are shown in Table 1, and from table, treatment group overall clinical efficacy rate is 96%, is significantly higher than matched group.

1 liang of table group Clinical efficacy comparison result n (%)

Group	n	Recovery from illness	Take a turn for the better	Invalid	Full blast
						Matched group	100	72	9	19	81%
Treatment group	100	88	8	4	96%

Treatment group compares with matched group, P ＜ 0.05；

A situation arises in 3.2 untoward reaction: treatment group matched group does not all find obvious adverse reaction.

4 conclusions

The nocturnal fretfulness in infants can effectively be treated by medicine the most of the present invention, and western medicine relatively is without obvious adverse reaction.

Model case

Certain boy baby of case 1 10 months, nighttime sleep is poor, easily cries and screams, and sob is humble, sleep happiness curls.Oral Chinese medicine composition decoction of the present invention, each 3 milliliters of every days, more than 5 times symptoms were alleviated for 3 days, within 7 days, eliminated.Pay a return visit without recurrence after 1 month.

Certain girl baby of case 28 months, when crying time before non-medication only, night sweat, anorexia, big loose stool is thin, clear urine in large amounts, and words are light red, pale tongue with white fur, light red superficial venule of the index finger.Oral Chinese medicine composition decoction of the present invention, each 2.5 milliliters of every days, more than 6 times symptoms were alleviated for 3 days, within 12 days, eliminated, paid a return visit without recurrence after 2 months.

Certain boy baby of case 31 years old, uneasiness of crying at nightfall, extremities being not warm, suck the breast unable, complexion is bluish white, coolness of extremities, happiness is lain prostrate.Oral medicine of the present invention, four times a day, alleviates, within 10 days, eliminates for 5 days by each 8 milliliters.Pay a return visit without recurrence after 3 months.

Claims (2)

1. treating a Chinese medicine composition for the nocturnal fretfulness in infants of Deficiency and coldness of spleen and stomach, its technical characteristic is, is made up of the activated feedstock of following parts by weight:

The Radix Linderae 4 ~ 12 parts, Rhizoma Alpiniae Officinarum 6 ~ 12 parts, Rhizoma Cyperi 4 ~ 9 parts, Pericarpium Citri Reticulatae 3 ~ 6 parts,

The Radix Aucklandiae 4 ~ 12 parts, Radix Platycodonis 2 ~ 6 parts, 2 ~ 10 parts of Radix Glycyrrhizae, the Radix Paeoniae Alba 2 ~ 8 parts,

Rhizoma Zingiberis Preparatum 2 ~ 10 parts, Fructus Amomi 2 ~ 6 parts, the Rhizoma Atractylodis Macrocephalae 2 ~ 6 parts, 2 ~ 6 parts of Poria,

Medulla Junci 1 ~ 6 part, Bombyx Batryticatus 3 ~ 12 parts, 0.3 ~ 1 part of Cinnabaris, Radix Puerariae 6 ~ 12 parts,

Periostracum Cicadae 2 ~ 6 parts, Herba Menthae 2 ~ 6 parts, Concha Margaritifera 9 ~ 15 parts, Radix Polygalae 3 ~ 12 parts,

Fructus Gardeniae 4 ~ 10 parts, 6 ~ 12 parts of Folium Bambusae, Ramulus Uncariae Cum Uncis 6 ~ 12 parts, Semen Sojae Preparatum 6 ~ 12 parts.

2. according to the Chinese medicine composition of a kind of nocturnal fretfulness in infants treating Deficiency and coldness of spleen and stomach described in claim 1, it is preferred that it is characterized in that: be made up of the activated feedstock of following parts by weight:

The Radix Linderae 8 parts, Rhizoma Alpiniae Officinarum 9 parts, Rhizoma Cyperi 6 parts, Pericarpium Citri Reticulatae 5 parts,

The Radix Aucklandiae 5 parts, Radix Platycodonis 4 parts, 3 parts of Radix Glycyrrhizae, the Radix Paeoniae Alba 6 parts,

Rhizoma Zingiberis Preparatum 9 parts, Fructus Amomi 6 parts, the Rhizoma Atractylodis Macrocephalae 3 parts, 3 parts of Poria,

Medulla Junci 2 parts, Bombyx Batryticatus 6 parts, 0.6 part of Cinnabaris, Radix Puerariae 9 parts,

Periostracum Cicadae 4 parts, Herba Menthae 4 parts, Concha Margaritifera 12 parts, Radix Polygalae 6 parts,

Fructus Gardeniae 7 parts, 9 parts of Folium Bambusae, Ramulus Uncariae Cum Uncis 9 parts, Semen Sojae Preparatum 9 parts.