CN106138648A - The liver benefiting effect of head and application thereof - Google Patents
The liver benefiting effect of head and application thereof Download PDFInfo
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- CN106138648A CN106138648A CN201510509120.9A CN201510509120A CN106138648A CN 106138648 A CN106138648 A CN 106138648A CN 201510509120 A CN201510509120 A CN 201510509120A CN 106138648 A CN106138648 A CN 106138648A
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- head
- extract
- decoction pieces
- preparation
- hepatitis
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Abstract
The invention discloses head purposes in preparing the liver benefiting effect product.With head as raw material, the liver benefiting product of all kinds of high-quality can be effectively converted to by extraction process and processing technique, including the health-care products of human and animal and natural drug goods and medicated diet.
Description
Technical field
The present invention relates to a kind of head process technology with the liver benefiting effect and the purposes in food, medicated diet, health food, natural drug,
Specifically, it is that fresh and dry head, deep processing and method for preparing extractive, head deep processed product, head extract, head are the most chemical
The application in the medicine of preparation hepatitis of purposes in preparing liver-protecting efficacy health product and medicated diet of composition, head, head.
Background technology
Liver is one of organ important in body, subjects the processed work of substantial amounts of biochemistry factory every day, to substantial amounts of through digestion
The food that road absorbs and other foreign substance carry out the processing of metabolism, are very easy to tired and sustain damage.Hepar damnification is the serious harm people
Healthy sick kind.China has more than the hepatitis B virus lifelong carrier of 100,000,000 people, the carrier of tens million of hepatitis C virus at present, the most thousands of
Wan Renhui is transformed into chronic hepatitis, liver cirrhosis, hepatocarcinoma, and because of hepatopathy, the people of death there are about hundreds of thousands of them every year.In recent years by being addicted to drink, medicine and each
The toxic hepar damnification planting harmful factor and cause increases the most increasingly.The annual expense for treating hepatopathy of China is up to tens billion of yuans, right
The physical and mental health of economy and social development particularly patient causes the biggest burden, so keeping the health of liver to become the target that people pursue.Food
Thing and medicine are the key factors affecting liver function, thus exploitation to be of value to the food of liver health, health food and new drug the most urgent.
Head (Allium chinense G.Don): be the herbaceous plant of a kind of Liliaceae Allium.English is Chinese onion；Japanese is
らっきぅ (peppery).Head bulb is also referred to as head, makees vegetable and eats.Head originates in China.The Yangtze river basin and on the south each provinces and regions extensively plant
Training, also has wild；Also there are cultivation in Japan, Vietnam, Laos, Cambodia and the U.S., but the area of plantation head does not all have the report of its anti-hepatitis.
The present invention this be to be found that head new application in edible, food, medicated diet, health food and medicine, processing method and having of containing
Effect composition etc..
Summary of the invention
It is an object of the invention to provide the new application of head, i.e. new opplication in preparing treating hepatitis medicine, health food and animal the liver benefiting product.
It is a further object of the present invention to provide the medicine of a kind for the treatment of hepatitis.
It is also another object of the present invention to provide the health food of a kind of hepatitis auxiliary treatment.
The purpose of the present invention also includes providing prepares good head extract of convenience, health care and therapeutic effect and preparation method thereof.
Inventor has carried out substantial amounts of deep processing research according to the processing method enemy of agricultural product, pickles beans, head including a dry powder, head
Powder, Mel head, head dumpling, head steamed bun, head wonton, head steamed dumplings, head cold vegetable dish in sauce, head grilled fish, head decoction pieces etc..Head
Taste after pickling is crisp sweet, can make the characteristic curry medicated diet with dual the liver benefiting effect together with purple potato block.
Head can directly eat, it is also possible to directly edible dry head.
Inventor is with reference to " 2003 annual drug research technological guidance principle-Chinese medicine, natural goods fascicle " (State Food and Drug Administration 2003
Year), " new drug preclinical study guideline " (country Bureau of Drugs Supervision 1993) and " function of health food assessment process " (Ministry of Public Health 2003)
Deng the drug evaluation method for the treatment of hepatitis and health food evaluation methodology, enemy has carried out that prepared by extract, prepared by pharmaceutical dosage form, animal drugs
Reason and pathological study.
Inventor finds that head has the effect of the liver benefiting.Head can make the decoction pieces of natural drug.After harvesting, its decoction pieces makes and is characterised by: will
Head is clean to be made and is dried.Head can direct using fresh herb, it is also possible to directly eat its dried bulb decoction pieces.
The preparation method of head extract is: can take pickled Chinese onion decoction pieces 1000g or proper amount of fresh head, boiling three times, each 15 minutes,
Collecting decoction, filters, and filtrate concentrates thick paste, continues dried, and fine powder processed to obtain final product.This product is the granule of brown；Lightly seasoned sweet.
Inventor finds, carries out oral administration and drug administration by injection with head extract, has an obvious effect, serum liver biochemical function index and
Pathological index all improves significantly.
When treating with head extract, it can be with form oral administrations such as powder, granule, tablet, capsule, pill and liquid preparations；
Can also be with form parenteral administration such as injection, suppository, percutaneous preparation, sprays.The effective agent of head extract, by with suitable
Medicinal blend, is configured to such as mixing such as excipient, binding agent, penetrating agent, lubricants.
Head extract doses changes with the state of an illness, route of administration, the age of patient and the body weight of patient.In the case of oral administration, dosage leads to
It is often adult 500～1000mg/ days, preferably 800mg/ days.Also it is same principle in health food application aspect.
The liver benefiting therapeutical effect that the invention have the advantage that head is to find first at home and the most all so that it is become 3G food.Head can
Using the natural drug as treatment hepatitis.
It addition, head preparation method is fairly simple, also comparing of plant growing the characteristic study is thorough, and there is cultivation in the whole nation, has the kind of certain scale
Phytyl ground, so the source of material and economy are the most secure.The market recognition of natural product is higher, and the acceptance in market is high, market prospect
Well.
Detailed description of the invention
Examples provided below is used for being further elucidated with the present invention, and is not meant to limit the scope of the invention.
Embodiment 1. material
Head decoction pieces used by embodiment we self-control.Briefly, gather in the crops head (leaf), summer and autumn spring and mainly gather in the crops head.Autumn receives
Obtain a seed.Other medicine, reagent and laboratory animal, can be the most commercial.
Embodiment 2. preparation method example
Taking a decoction pieces 1000g, wash 3 times, the 3000ml that adds water decocts, totally three times, each 20 minutes, collecting decoction, filters, filtrate
It is condensed into thick paste, continues to be evaporated to do, obtain brown ceramic powder about 40g.
Embodiment 3. example of formulations,
(1) preparation method taking 1kg embodiment 2 obtains the head extract of each plant parts, pulverizes and crosses 100 mesh sieves, adds appropriate shallow lake
Powder mixes, and prepares granule, carries out subpackage, every bag of 2g after granulate.
(2) head extract 1000g, the hydroxyethyl cellulose 10g that the preparation method of Example 2 obtains, tablet made by tabletting.
(3) the head extract that the preparation method of embodiment 2 obtains is dissolved in normal saline or isotonic Glucose Liquid, uses on demand after filtered
The injection of preparation.
(4) the head extract that the preparation method of embodiment 2 obtains is dissolved in water, can be formulated directly into oral liquid.
(5) the head extract that the preparation method of embodiment 2 obtains can coordinate with the medicine such as Radix Isatidis extract and makes compound mixture for treating
Hepatitis.
Embodiment 4. effect experiment
(1) evaluation methodology
The drug efficacy study part of head extract for treating hepatitis
Laboratory animal is adult healthy male CD-1 mice.Enough tap waters and normal diet are provided during test.The packet of animal and process:
By mice by body weight random packet.For to be administered for three days on end in the observation of curative effect of hepatitis, once a day.Within 4th day, take blood and leave and take animal livers,
Measure liver function enzyme alanine transaminase (ALT) in serum, observe hepatic pathology intensity of variation.Experimental data represents with mean ± standard deviation.Application
Experimental result is used the methods analyst such as variance analysis, t inspection to process by EXCEL statistical software, and p ＜ 0.05 thinks that group difference has significance.
(2) evaluation result (table 1): head all has the good effect protecting the liver anti-toxic hepatitis.
The effect of 1 extract anti-carbon tetrachloride poisoning hepatitis of table
Note: ## compares p ＜ 0.05 with matched group.*, * * compares p ＜ 0.05 with poisoning hepatitis model group；P ＜ 0.01.
Claims (7)
1. for preparation, there is the plant product to human and animal's the liver benefiting effect, it is characterised in that containing head (Allium chinense G.Don) or carry
Take thing.
2. can make natural decoction pieces.Head can direct using fresh herb, it is also possible to directly eat its dried decoction pieces.
3. a head extract, it is characterised in that adopt and prepare with the following method, takes a decoction pieces or fresh head, only makes, boiling three times,
Each 15 minutes, collecting decoction, filter, filtrate concentrates thick paste.Or thick paste is dried, prepare fine powder.
The most according to claim 3 extract, it is characterised in that extract fine powder can make together with suitable medical dressing oral formulations,
The multiple dosage forms such as injection, granule, tablet, capsule, pill, powder.Can also be with other medicines or other plant extract compatibility
Composition compound preparation.
5. the medicine for hepatitis auxiliary treatment, it is characterised in that containing the head decoction pieces described in claim 2 and 3 or extract.
6. the health product for the liver benefiting, it is characterised in that containing the head decoction pieces described in claim 2 and 3 or extract.
7. the application in the medicine of preparation hepatitis and health product and medicated diet of head decoction pieces or described in claim 2 and 3 or extract.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510509120.9A CN106138648A (en) | 2015-08-19 | 2015-08-19 | The liver benefiting effect of head and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510509120.9A CN106138648A (en) | 2015-08-19 | 2015-08-19 | The liver benefiting effect of head and application thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106138648A true CN106138648A (en) | 2016-11-23 |
Family
ID=57348071
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510509120.9A Withdrawn CN106138648A (en) | 2015-08-19 | 2015-08-19 | The liver benefiting effect of head and application thereof |
Country Status (1)
| Country | Link |
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| CN (1) | CN106138648A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106727872A (en) * | 2017-01-20 | 2017-05-31 | 北京健旭康技术有限公司 | The beneficial liver effect of poinsettia and application technology |
-
2015
- 2015-08-19 CN CN201510509120.9A patent/CN106138648A/en not_active Withdrawn
Non-Patent Citations (1)
| Title |
|---|
| 雷荣剑等: "藠头总甾体皂苷对高脂大鼠降脂作用研究", 《中成药》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106727872A (en) * | 2017-01-20 | 2017-05-31 | 北京健旭康技术有限公司 | The beneficial liver effect of poinsettia and application technology |
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| Date | Code | Title | Description |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20161123 |