CN106136243A - A kind of Sargassum extract health care soft capsule - Google Patents
A kind of Sargassum extract health care soft capsule Download PDFInfo
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- CN106136243A CN106136243A CN201610730359.3A CN201610730359A CN106136243A CN 106136243 A CN106136243 A CN 106136243A CN 201610730359 A CN201610730359 A CN 201610730359A CN 106136243 A CN106136243 A CN 106136243A
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- semen lini
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- 239000007901 soft capsule Substances 0.000 title claims abstract description 30
- 230000036541 health Effects 0.000 title claims abstract description 25
- 241000195474 Sargassum Species 0.000 title claims abstract description 21
- 239000003921 oil Substances 0.000 claims abstract description 117
- 239000002671 adjuvant Substances 0.000 claims abstract description 28
- 239000000463 material Substances 0.000 claims abstract description 16
- 239000002775 capsule Substances 0.000 claims abstract description 15
- 239000002994 raw material Substances 0.000 claims abstract description 12
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- 235000014593 oils and fats Nutrition 0.000 claims abstract description 5
- 230000002262 irrigation Effects 0.000 claims abstract description 4
- 238000003973 irrigation Methods 0.000 claims abstract description 4
- 238000003756 stirring Methods 0.000 claims description 35
- 238000000034 method Methods 0.000 claims description 19
- 239000000843 powder Substances 0.000 claims description 18
- 230000008569 process Effects 0.000 claims description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 15
- 239000000344 soap Substances 0.000 claims description 12
- 238000002156 mixing Methods 0.000 claims description 10
- 239000003513 alkali Substances 0.000 claims description 9
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- 239000011162 core material Substances 0.000 claims description 8
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 6
- 229920000615 alginic acid Polymers 0.000 claims description 6
- 235000010443 alginic acid Nutrition 0.000 claims description 6
- 238000004140 cleaning Methods 0.000 claims description 6
- 238000004332 deodorization Methods 0.000 claims description 6
- 238000000605 extraction Methods 0.000 claims description 6
- 239000012535 impurity Substances 0.000 claims description 6
- 150000003904 phospholipids Chemical class 0.000 claims description 6
- 238000005406 washing Methods 0.000 claims description 6
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims description 5
- 229940072056 alginate Drugs 0.000 claims description 5
- 238000001035 drying Methods 0.000 claims description 5
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- 229910052799 carbon Inorganic materials 0.000 claims description 4
- 239000008187 granular material Substances 0.000 claims description 4
- 102100034279 Calcium-binding mitochondrial carrier protein Aralar2 Human genes 0.000 claims description 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 3
- 239000002253 acid Substances 0.000 claims description 3
- 239000003463 adsorbent Substances 0.000 claims description 3
- 238000009874 alkali refining Methods 0.000 claims description 3
- 239000007864 aqueous solution Substances 0.000 claims description 3
- 108010084210 citrin Proteins 0.000 claims description 3
- 239000000084 colloidal system Substances 0.000 claims description 3
- 239000000839 emulsion Substances 0.000 claims description 3
- 239000004744 fabric Substances 0.000 claims description 3
- 238000011049 filling Methods 0.000 claims description 3
- 239000004519 grease Substances 0.000 claims description 3
- 238000010438 heat treatment Methods 0.000 claims description 3
- 230000036571 hydration Effects 0.000 claims description 3
- 238000006703 hydration reaction Methods 0.000 claims description 3
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 claims description 3
- 229910052753 mercury Inorganic materials 0.000 claims description 3
- 239000011859 microparticle Substances 0.000 claims description 3
- 239000002245 particle Substances 0.000 claims description 3
- 239000002244 precipitate Substances 0.000 claims description 3
- 238000002360 preparation method Methods 0.000 claims description 3
- 238000012216 screening Methods 0.000 claims description 3
- 239000008234 soft water Substances 0.000 claims description 3
- 239000002351 wastewater Substances 0.000 claims description 3
- 230000009471 action Effects 0.000 claims description 2
- 238000000227 grinding Methods 0.000 claims description 2
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- 108010023302 HDL Cholesterol Proteins 0.000 description 5
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- 241000699670 Mus sp. Species 0.000 description 5
- 210000004958 brain cell Anatomy 0.000 description 5
- 239000003925 fat Substances 0.000 description 5
- 210000002966 serum Anatomy 0.000 description 5
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 5
- 239000002585 base Substances 0.000 description 4
- 210000004556 brain Anatomy 0.000 description 4
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- 235000016709 nutrition Nutrition 0.000 description 3
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- 210000004051 gastric juice Anatomy 0.000 description 2
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- 241000699666 Mus <mouse, genus> Species 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 102100037204 Sal-like protein 1 Human genes 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
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- 229960001126 alginic acid Drugs 0.000 description 1
- 239000000783 alginic acid Substances 0.000 description 1
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- 239000000835 fiber Substances 0.000 description 1
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- 238000004519 manufacturing process Methods 0.000 description 1
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- 208000015380 nutritional deficiency disease Diseases 0.000 description 1
- 210000004279 orbit Anatomy 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 210000002381 plasma Anatomy 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 210000000582 semen Anatomy 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- NRHMKIHPTBHXPF-TUJRSCDTSA-M sodium cholate Chemical compound [Na+].C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC([O-])=O)C)[C@@]2(C)[C@@H](O)C1 NRHMKIHPTBHXPF-TUJRSCDTSA-M 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The invention discloses a kind of Sargassum extract health care soft capsule, added adjuvant by core-clad material to form through automatic rotary transformation of ownership mechanical irrigation dress, the core-clad material of capsule is made up of following raw material, split the DHA 20～30 parts extracted in kettle algae or dinoflagellate, in Chlorococcum extract EPA 10～20 parts, ARA 10～20 parts, Semen Lini oil 30～50 parts.Several high-end oils and fatss such as DHA, EPA, ARA, Semen Lini oil are raw material by the present invention, use the processing method improved to be manufactured and become soft capsule, easy for carrying and eating, absorption of human body utilization rate is high, has enhancing immunity, promotes hair cell growth, prevention senile dementia, enhancement blood circulation, blood fat reducing and effect of blood pressure lowering.
Description
Technical field
The present invention relates to a kind of health product, a kind of Sargassum extract health care soft capsule.
Background technology
According to the nutrition report display of the up-to-date whole world, malnutrition is the major incentive that global disease spreads.Along with people live
Level the highest, people are more and more urgent to the food demand with health-care effect, have the food of health-care effect currently on the market
Product effect is single or has serious deficiency, therefore innovates a kind of new health care of food capsule with composite efficacy and has wide
Market prospect.
DHA is the high-grade nutrient hardening agent that a kind of human body can not self synthesize, and is referred to as " NAOHUANGJIN " by image.Result of study
Show that DHA is as brain development, one of important substance of growth.Being the composition that mainly comprises of people's brain cell, DHA is easy to pass through
Brain barrier enters brain cell, is present in brain cell and cell process, and in human brain cytolipin, 10% is DHA.It is to constitute brain phosphorus
Fat, the basis of brain cell membrane, the division of brain cell, propagation, nerve conduction, the g and D of synapse are played particularly important
Effect, is that human brain is formed and the required material of IQ exploitation.It to vision, cerebral activity, lipid metabolism, fetal growth,
And immunologic function and avoid alzheimer disease to have extreme influence.The health promoting product containing DHA in the market is of a great variety, but
The collocation of other nutrients is not reasonable, at the bottom of the purity of like product, unstable properties, not only can affect the absorption to DHA,
And do not have more preferable health-care effect, it is difficult to effectively play the effect of DHA.
Summary of the invention
The technical problem to be solved is to provide a kind of Sargassum extract health care soft capsule.
For solving above-mentioned technical problem, the technical scheme is that a kind of Sargassum extract health care soft capsule, by capsule-core
Thing add adjuvant through the automatic rotary transformation of ownership mechanical irrigation dress form, the core-clad material of capsule is made up of following raw material: split kettle algae or
In dinoflagellate extract DHA 20～30 parts, in Chlorococcum extract EPA 10～20 parts, ARA 10～20 parts, Semen Lini oil 30～
50 parts.
As further technical scheme, the consumption of described adjuvant accounts for the 33%～35% of core-clad material weight portion, adjuvant by with
The raw material of lower weight portion is prepared from: Rhizoma Dioscoreae powder 50～60 parts, Fructus Crataegi powder 20～30 parts, Aspidlsiraelatior 10～15 parts, brown sugar 5～8
Part, alginate 1～2 parts；Adjuvant is obtained by following steps: is 1. cleaned with clear water by the fresh Aspidlsiraelatior plucked, drains the water
After Fen, with dehydrator with 60～70 DEG C of drying, dry crumbing to blade；2. the Aspidlsiraelatior after drying puts into grounds travel
Broken machine is pulverized, and makes Aspidlsiraelatior powder；Take Aspidlsiraelatior powder, Rhizoma Dioscoreae powder, Fructus Crataegi powder, brown sugar, alginic acid the most by weight
Salt is sufficiently mixed stirring and is placed in hermetic container, places 24 hours to seal higher than the temperature 40 of room temperature～50 DEG C, i.e. makes
Adjuvant.
As further technical scheme, described a kind of Sargassum extract health care soft capsule, it is made up of following steps:
Step one, the extraction of Semen Lini oil
1. carry out the impurity in Semen Lini screening, filter, dedusting cleaning, the Semen Lini impurity content after cleaning must not exceed
0.1%；The most then Semen Lini is put into frying pan and propagandizes 10 minutes hotly；3. the Semen Lini after propagandizing hotly is put into squeezer and is squeezed；④
Being filtered by the Semen Lini oil filter cloth device squeezed out, during filtration, pressure is less than 4kg/c；5. the Semen Lini after filtering
Oil is squeezed into hydration tank and is carried out aquation degumming process, first heats up, and oil temperature reaches aquation when 70～75 DEG C, the stirring speed of 60 revs/min
Degree is lower to add oil and weighs 2～3% with oil temperature saline solution, stirs 30 minutes, when having phospholipid microparticles to separate with oils and fats, is down to mixing speed
Being 30 revs/min, until the cohesion of phospholipid particle in when being clearly separated, stop stirring, now oil temperature rises to 75～80 DEG C, precipitates 8 hours
More than proceed to next procedure；6. the Semen Lini oil after aquation degumming is carried out deacidification process；7. the negative pressure in bleacher is utilized to incite somebody to action
Semen Lini oil after deacidification process decolours in sucking bleacher；8. the Semen Lini oil of decolouring is sucked in odor removing pot,
When useful load reaches the 3/5 of total capacity, stop oil-feed, then carry out deodorize process；9. finally Semen Lini oil to cooling tank is crystallized,
In 48 hours, oil temperature is down to 0, keeps oil temperature 2～3 hours growing the grains, then cooling Semen Lini oil is moved to thermostatic tank and treat oil temperature
Rise to 25 DEG C and be filtrated to get refined Semen Lini oil；
Step 2, the preparation of capsule core material
The refined Semen Lini oil obtained is extracted in the DHA of extraction, Chlorococcum with splitting in kettle algae or dinoflagellate respectively according to weight portion
EPA, ARA raw material be sufficiently mixed, and be stirred continuously, stir 10～15 minutes, then according to amount ratio adds adjuvant, add
It is again stirring for after adjuvant 10～15 minutes, is eventually adding core-clad material and the colloid of adjuvant weight portion 3 times, after stirring, makes capsule
Core compositions；
Step 3, prepare soft capsule
Core-clad material compositions is added filling formation in automatic rotary transformation of ownership capsule machine and is pressed into soft capsule, obtain Sargassum extract health care
Soft capsule granule.
As preferably, the 6. deacidification of described step one processes and concretely comprises the following steps:
1) according to acid value and the oil mass of Semen Lini oil, obtain required concentration of lye and quantity, join alkali；
2) valency alkali neutralizes, and adds the alkali liquor prepared within the time of 10 minutes, stirs 20～60 points with the speed of 60 revs/min
Clock, in emulsion when oil and the separated state of neat soap, is heated to 65～70 DEG C with the programming rate of 1～1.5 degree min, reduces
Mixing speed 30 revs/min, after stirring 10 minutes, oil and neat soap, in when being clearly separated state, stop stirring；
3) staticly settle 6～8 hours, lower floor's oil foot is moved in soap stock pot, surplus absolute oil in alkali refining tank；
4) washing, is heated to 70 DEG C by absolute oil, adds the soft water of 65～70 DEG C, amount of water under 15～30 turn, point mixing speeds
For the 8～10% of oil weight, to wash away the neat soap of remaining in absolute oil, stand 1～2 hour, put washing waste water and complete deacidification.
As preferably, what 7. described step one decoloured concretely comprises the following steps:
1) opening vacuum pump, the Semen Lini oil after utilizing the negative pressure in bleacher deacidification to be processed sucks in bleacher, loads tank
After 60% volume of body volume, temperature is raised to 90～100 DEG C, and vacuum is not less than 700 millimetress of mercury, uniform stirring 15 minutes, fall
Low grease water content is below 0.1%；
2) turning down vacuum valve, open adsorbent suction inlet valve, suck activated carbon and the bleaching clay bleaching clay of 1%, consumption is the 2～5% of oil weight,
Maintaining the former pressure of former temperature, stir 30 minutes, stop heating, breaking vacuum, oil temperature is cooled to less than 60 DEG C, filters；
3) oil after cooling is passed through the filtration of multiple filter, and the oil after filter can not contain bleaching clay.
As preferably, concretely comprising the following steps of described step one 8. deodorize:
1) open vacuum equipment, by means of negative pressure, Semen Lini oil is sucked in odor removing pot, when useful load reaches the 3/5 of total capacity, stop into
Oil；
2) oil temperature reaches 150 DEG C, and live (open) steam pressure is not less than 1 atmospheric pressure, and now deodorize starts, and heavy with now adding oil
The citrin aqueous solution of 0.01 ~ 0.02% is in oil；
3) stripped vapor consumption is 30 ~ 50KG/T, and deodorization temperature controls at 180～250 DEG C, Stress control at below 0.6kPa,
Deodorization time 2.5～4h.
The method have the advantages that
1, several high-end oils and fatss such as DHA, EPA, ARA, Semen Lini oil are raw material by the present invention, use the processing method improved by it
Manufacturing and become soft capsule, easy for carrying and eating, absorption of human body utilization rate is high, have enhancing immunity, promote hair cell growth,
Prevention senile dementia, enhancement blood circulation, blood fat reducing and effect of blood pressure lowering.
2, soft capsule dosage form is as health product carrier, has a mitigation, decrease gastric acid to health product after taking
The destruction of effective ingredient, along with soft capsule slowly melts, DHA therein, EPA, ARA, Semen Lini oil nutritional labeling by slowly
Discharge, the Fructus Crataegi composition in adjuvant can stimulate stomach, helps lend some impetus to DHA, EPA, ARA, Semen Lini pick up the oil,
And the starch that Rhizoma Dioscoreae in adjuvant, Aspidlsiraelatior composition contain, Plant fiber can more consume gastric juice during decomposing,
Form complementation with Fructus Crataegi, and then formation gastric juice balances dynamically, fully absorbing of the most each nutritional labeling, solves similar product
Product purity is low, the problem of unstable properties, weak effect, takes full advantage of DHA, EPA in Sargassum and assists enhancing immunity, blood fat reducing
Effect, and make DHA, EPA, ARA, Semen Lini oil and adjuvant organically combine and reach health-care effect.
Detailed description of the invention
Embodiment 1
A kind of Sargassum extract health care soft capsule, is added adjuvant by core-clad material and forms through automatic rotary transformation of ownership mechanical irrigation dress, capsule
Core-clad material is made up of following raw material: split the DHA 15 parts extracted in kettle algae or dinoflagellate, the EPA 15 extracted in Chlorococcum
Part, ARA 15 parts, Semen Lini oil 40 parts, the consumption of described adjuvant accounts for the 33%～35% of core-clad material weight portion, and adjuvant is by following heavy
The raw material of amount part is prepared from: Rhizoma Dioscoreae powder 55 parts, Fructus Crataegi powder 25 parts, Aspidlsiraelatior 12 parts, 6 parts of brown sugar, alginate 2 parts；Adjuvant
Obtained by following steps: 1. the fresh Aspidlsiraelatior plucked is cleaned with clear water, after draining away the water, with dehydrator with 60～70 DEG C
Dry, dry crumbing to blade；2. the Aspidlsiraelatior after drying is put into grinding and crushing machine and pulverizes, and makes Aspidlsiraelatior
Powder；Take Aspidlsiraelatior powder the most by weight, Rhizoma Dioscoreae powder, Fructus Crataegi powder, brown sugar, alginate are sufficiently mixed stirring and are placed on airtight
In container, place 24 hours to seal higher than the temperature 40 of room temperature～50 DEG C, i.e. make adjuvant.
Above-mentioned Sargassum extract health care soft capsule, it is made up of following steps:
Step one, the extraction of Semen Lini oil
1. carry out the impurity in Semen Lini screening, filter, dedusting cleaning, the Semen Lini impurity content after cleaning must not exceed
0.1%；
The most then Semen Lini is put into frying pan and propagandizes 10 minutes hotly；
3. the Semen Lini after propagandizing hotly is put into squeezer and is squeezed；
4. being filtered by the Semen Lini oil filter cloth device squeezed out, during filtration, pressure is less than 4kg/c；
5. the Semen Lini oil after filtering is squeezed into hydration tank and is carried out aquation degumming process, first heats up, and oil temperature reaches water when 70～75 DEG C
Change, under the mixing speed of 60 revs/min, add oil weigh 2～3% with oil temperature saline solution, stir 30 minutes, have phospholipid microparticles and oils and fats
During separation, being down to mixing speed is 30 revs/min, until the cohesion of phospholipid particle in when being clearly separated, stops stirring, and now oil temperature rises to
75～80 DEG C, precipitate and proceed to next procedure in more than 8 hours；
6. the Semen Lini oil after aquation degumming is carried out deacidification process, comprises the following steps:
1) according to acid value and the oil mass of Semen Lini oil, obtain required concentration of lye and quantity, join alkali；
2) valency alkali neutralizes, and adds the alkali liquor prepared within the time of 10 minutes, stirs 20～60 points with the speed of 60 revs/min
Clock, in emulsion when oil and the separated state of neat soap, is heated to 65～70 DEG C with the programming rate of 1～1.5 degree min, reduces
Mixing speed 30 revs/min, after stirring 10 minutes, oil and neat soap, in when being clearly separated state, stop stirring；
3) staticly settle 6～8 hours, lower floor's oil foot is moved in soap stock pot, surplus absolute oil in alkali refining tank；
4) washing, is heated to 70 DEG C by absolute oil, adds the soft water of 65～70 DEG C, amount of water under 15～30 turn, point mixing speeds
For the 8～10% of oil weight, to wash away the neat soap of remaining in absolute oil, stand 1～2 hour, put washing waste water and complete deacidification；
7. the Semen Lini oil after utilizing the negative pressure in bleacher deacidification to be processed decolours in sucking bleacher, concrete steps
For:
1) opening vacuum pump, the Semen Lini oil after utilizing the negative pressure in bleacher deacidification to be processed sucks in bleacher, loads tank
After 60% volume of body volume, temperature is raised to 90～100 DEG C, and vacuum is not less than 700 millimetress of mercury, uniform stirring 15 minutes, fall
Low grease water content is below 0.1%；
2) turning down vacuum valve, open adsorbent suction inlet valve, suck activated carbon and the bleaching clay bleaching clay of 1%, consumption is the 2～5% of oil weight,
Maintaining the former pressure of former temperature, stir 30 minutes, stop heating, breaking vacuum, oil temperature is cooled to less than 60 DEG C, filters；
3) oil after cooling is passed through the filtration of multiple filter, and the oil after filter can not contain bleaching clay；
8. the Semen Lini oil of decolouring is sucked in odor removing pot, when useful load reaches the 3/5 of total capacity, stop oil-feed, then carry out
Deodorize processes, and concretely comprises the following steps:
1) open vacuum equipment, by means of negative pressure, Semen Lini oil is sucked in odor removing pot, when useful load reaches the 3/5 of total capacity, stop into
Oil；
2) oil temperature reaches 150 DEG C, and live (open) steam pressure is not less than 1 atmospheric pressure, and now deodorize starts, and heavy with now adding oil
The citrin aqueous solution of 0.01 ~ 0.02% is in oil；
3) stripped vapor consumption is 30 ~ 50KG/T, and deodorization temperature controls at 180～250 DEG C, Stress control at below 0.6kPa,
Deodorization time 2.5～4h.
9. finally Semen Lini oil to cooling tank is crystallized, in 48 hours, oil temperature is down to 0, keep oil temperature 2～support for 3 hours
Crystalline substance, then moves cooling Semen Lini oil and treats that oil temperature rises to 25 DEG C and is filtrated to get refined Semen Lini oil to thermostatic tank；
Step 2, the preparation of capsule core material
The refined Semen Lini oil obtained is extracted in the DHA of extraction, Chlorococcum with splitting in kettle algae or dinoflagellate respectively according to weight portion
EPA, ARA raw material be sufficiently mixed, and be stirred continuously, stir 10～15 minutes, then according to amount ratio adds adjuvant, add
It is again stirring for after adjuvant 10～15 minutes, is eventually adding core-clad material and the colloid of adjuvant weight portion 3 times, after stirring, makes capsule
Core compositions；
Step 3, prepare soft capsule
Core-clad material compositions is added filling formation in automatic rotary transformation of ownership capsule machine and is pressed into soft capsule, obtain Sargassum extract health care
Soft capsule granule.
Embodiment 2 present invention influence research to mice hyperlipidemia
Select ICR kind mice, feed ingredient, powdered base feedstuff: Semen Maydis flour 30%, flour 30%, Testa Tritici 35%, fish flour 2%, bone meal
2%, Sal 1%；
Powdery high lipid food (uses with other feed collocations): containing cholesterol 1.5%, sodium cholate 0.5%, Adeps Sus domestica 5%；
This experiment selects mice Mus age to be 4 weeks, and body weight 20～24g/, male, after normal feedstuff adapts to 1 week, mice is random
It is divided into 4 groups, often group 11.(1) Normal group (A group): raising with powdered base feedstuff, 24h feeds water；(2) high fat matched group (B
Group): raising the powdery high lipid food with 7% and the powdered base feedstuff of 93%, 24h feeds water；(3) model experiment group (C group): raise with 7%
The Sargassum extract health care soft capsule produced of the present invention of powdery high lipid food, the powdered base feedstuff of 73% and 20%
Grain；Feeding manner uses and freely takes food, and feeding time is 20 days.
Body weight: claim the weight (g) of every Mus before and after experiment processes respectively with balance weighing apparatus.
Blood plasma lipide: take a blood sample after 20 days, fasting 12h before blood sampling, eye socket takes blood 0.75ml, 5000r/min after 37 DEG C of insulations
Centrifugation serum, record serum total cholesterol (TC), serum levels of triglyceride (TG), HDL-C (HDL-C),
Low-density lipoprotein cholesterol (LDL-C).
The body weight (g) of mice before and after raising
| Before and after raising | A | B | C |
| Before | 28.2±1.0 | 28.1±1.2 | 28.1±1.1 |
| After | 32.0±1.5 | 32.9±1.7 | 32.0±1.6 |
The each group of impact on bloodlipids character index (mmol/L)
| Group | TG | TC | HDL-C | LDL-C |
| A | 0.69±0.22 | 2.74±0.35 | 1.08±0.28 | 1.39±0.17 |
| B | 1.46±0.33 | 7.82±1.28 | 5.80±1.56 | 1.75±0.21 |
| C | 1.06±0.30 | 6.60±1.0 | 4..85±1.1 | 1.44±0.12 |
Can be drawn by upper table, C group with A group (Normal group) although comparing and having unconspicuous gap, but C group and B group (high fat pair
According to group) compare, serum levels of triglyceride (TG), serum total cholesterol (TC), HDL-C (HDL-C), low-density
Lipoprotein cholesterol (LDL-C) reduces by 27.4%, 15.6%, 16.4%, 17.7% respectively, declines the most obvious, it is clear that C group is added
Sargassum extract health care soft capsule granule of the present invention there is obvious antilipemic healthy function.
The equipment used in the present invention is the common equipment of this area, does not repeats them here.
The foregoing is only the schematic detailed description of the invention of the present invention, be not limited to the scope of the present invention.Any
Those skilled in the art, equivalent variations done on the premise of without departing from the design of the present invention and principle and amendment, all
The scope of protection of the invention should be belonged to.
Claims (6)
1. a Sargassum extract health care soft capsule, is added adjuvant by core-clad material and forms through automatic rotary transformation of ownership mechanical irrigation dress, and it is special
Levying and be, the core-clad material of capsule is made up of following raw material: split the DHA 20～30 parts extracted in kettle algae or dinoflagellate, green ball
In algae extract EPA 10～20 parts, ARA 10～20 parts, Semen Lini oil 30～50 parts.
2. a kind of Sargassum extract health care soft capsule as claimed in claim 1, it is characterised in that: the consumption of described adjuvant accounts for capsule
The 33%～35% of core thing weight portion, adjuvant is prepared from by the raw material of following weight portion: Rhizoma Dioscoreae powder 50～60 parts, Fructus Crataegi powder 20～
30 parts, Aspidlsiraelatior 10～15 parts, brown sugar 5～8 parts, alginate 1～2 parts；Adjuvant is obtained by following steps: 1. new by pluck
Fresh Aspidlsiraelatior clear water is cleaned, and after draining away the water, with dehydrator with 60～70 DEG C of drying, dries crumbing to blade；
2. the Aspidlsiraelatior after drying is put into grinding and crushing machine and pulverizes, and makes Aspidlsiraelatior powder；Take Aspidlsiraelatior powder the most by weight
End, Rhizoma Dioscoreae powder, Fructus Crataegi powder, brown sugar, alginate are sufficiently mixed stirring and are placed in hermetic container, with the temperature 40 higher than room temperature
～50 DEG C seal place 24 hours, i.e. make adjuvant.
3. a kind of Sargassum extract health care soft capsule as claimed in claim 1 or 2, it is characterised in that be made up of following steps:
Step one, the extraction of Semen Lini oil
1. carry out the impurity in Semen Lini screening, filter, dedusting cleaning, the Semen Lini impurity content after cleaning must not exceed
0.1%；The most then Semen Lini is put into frying pan and propagandizes 10 minutes hotly；3. the Semen Lini after propagandizing hotly is put into squeezer and is squeezed；④
Being filtered by the Semen Lini oil filter cloth device squeezed out, during filtration, pressure is less than 4kg/c；5. the Semen Lini after filtering
Oil is squeezed into hydration tank and is carried out aquation degumming process, first heats up, and oil temperature reaches aquation when 70～75 DEG C, the stirring speed of 60 revs/min
Degree is lower to add oil and weighs 2～3% with oil temperature saline solution, stirs 30 minutes, when having phospholipid microparticles to separate with oils and fats, is down to mixing speed
Being 30 revs/min, until the cohesion of phospholipid particle in when being clearly separated, stop stirring, now oil temperature rises to 75～80 DEG C, precipitates 8 hours
More than proceed to next procedure；6. the Semen Lini oil after aquation degumming is carried out deacidification process；7. the negative pressure in bleacher is utilized to incite somebody to action
Semen Lini oil after deacidification process decolours in sucking bleacher；8. the Semen Lini oil of decolouring is sucked in odor removing pot,
When useful load reaches the 3/5 of total capacity, stop oil-feed, then carry out deodorize process；9. finally Semen Lini oil to cooling tank is crystallized,
In 48 hours, oil temperature is down to 0, keeps oil temperature 2～3 hours growing the grains, then cooling Semen Lini oil is moved to thermostatic tank and treat oil temperature
Rise to 25 DEG C and be filtrated to get refined Semen Lini oil；
Step 2, the preparation of capsule core material
The refined Semen Lini oil obtained is extracted in the DHA of extraction, Chlorococcum with splitting in kettle algae or dinoflagellate respectively according to weight portion
EPA, ARA raw material be sufficiently mixed, and be stirred continuously, stir 10～15 minutes, then according to amount ratio adds adjuvant, add
It is again stirring for after adjuvant 10～15 minutes, is eventually adding core-clad material and the colloid of adjuvant weight portion 3 times, after stirring, makes capsule
Core compositions；
Step 3, prepare soft capsule
Core-clad material compositions is added filling formation in automatic rotary transformation of ownership capsule machine and is pressed into soft capsule, obtain Sargassum extract health care
Soft capsule granule.
4. a kind of Sargassum extract health care soft capsule as claimed in claim 3, it is characterised in that the 6. deacidification of described step one
Process concretely comprises the following steps:
1) according to acid value and the oil mass of Semen Lini oil, obtain required concentration of lye and quantity, join alkali；
2) valency alkali neutralizes, and adds the alkali liquor prepared within the time of 10 minutes, stirs 20～60 points with the speed of 60 revs/min
Clock, in emulsion when oil and the separated state of neat soap, is heated to 65～70 DEG C with the programming rate of 1～1.5 degree min, reduces
Mixing speed 30 revs/min, after stirring 10 minutes, oil and neat soap, in when being clearly separated state, stop stirring；
3) staticly settle 6～8 hours, lower floor's oil foot is moved in soap stock pot, surplus absolute oil in alkali refining tank；
4) washing, is heated to 70 DEG C by absolute oil, adds the soft water of 65～70 DEG C, amount of water under 15～30 turn, point mixing speeds
For the 8～10% of oil weight, to wash away the neat soap of remaining in absolute oil, stand 1～2 hour, put washing waste water and complete deacidification.
5. a kind of Sargassum extract health care soft capsule as claimed in claim 3, it is characterised in that 7. described step one decolours
Concretely comprise the following steps:
1) opening vacuum pump, the Semen Lini oil after utilizing the negative pressure in bleacher deacidification to be processed sucks in bleacher, loads tank
After 60% volume of body volume, temperature is raised to 90～100 DEG C, and vacuum is not less than 700 millimetress of mercury, uniform stirring 15 minutes, fall
Low grease water content is below 0.1%；
2) turning down vacuum valve, open adsorbent suction inlet valve, suck activated carbon and the bleaching clay bleaching clay of 1%, consumption is the 2～5% of oil weight,
Maintaining the former pressure of former temperature, stir 30 minutes, stop heating, breaking vacuum, oil temperature is cooled to less than 60 DEG C, filters；
3) oil after cooling is passed through the filtration of multiple filter, and the oil after filter can not contain bleaching clay.
6. a kind of Sargassum extract health care soft capsule as claimed in claim 3, it is characterised in that the 8. deodorize of described step one
Concretely comprise the following steps:
1) open vacuum equipment, by means of negative pressure, Semen Lini oil is sucked in odor removing pot, when useful load reaches the 3/5 of total capacity, stop into
Oil；
2) oil temperature reaches 150 DEG C, and live (open) steam pressure is not less than 1 atmospheric pressure, and now deodorize starts, and heavy with now adding oil
The citrin aqueous solution of 0.01 ~ 0.02% is in oil；
3) stripped vapor consumption is 30 ~ 50KG/T, and deodorization temperature controls at 180～250 DEG C, Stress control at below 0.6kPa,
Deodorization time 2.5～4h.
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