CN106136232A - A kind of preparation method of beneficial bacteria factor composite chewable tablet - Google Patents
A kind of preparation method of beneficial bacteria factor composite chewable tablet Download PDFInfo
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- CN106136232A CN106136232A CN201610499407.2A CN201610499407A CN106136232A CN 106136232 A CN106136232 A CN 106136232A CN 201610499407 A CN201610499407 A CN 201610499407A CN 106136232 A CN106136232 A CN 106136232A
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- 241000894006 Bacteria Species 0.000 title claims abstract description 40
- 230000009286 beneficial effect Effects 0.000 title claims abstract description 39
- 239000007910 chewable tablet Substances 0.000 title claims abstract description 34
- 229940068682 chewable tablet Drugs 0.000 title claims abstract description 34
- 238000002360 preparation method Methods 0.000 title claims abstract description 16
- 239000002131 composite material Substances 0.000 title claims abstract description 15
- 239000007788 liquid Substances 0.000 claims abstract description 33
- 235000015203 fruit juice Nutrition 0.000 claims abstract description 22
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims abstract description 21
- 229940059442 hemicellulase Drugs 0.000 claims abstract description 21
- 108010002430 hemicellulase Proteins 0.000 claims abstract description 21
- 239000007779 soft material Substances 0.000 claims abstract description 19
- 238000001914 filtration Methods 0.000 claims abstract description 15
- 239000000203 mixture Substances 0.000 claims abstract description 14
- 238000000034 method Methods 0.000 claims abstract description 13
- 239000000843 powder Substances 0.000 claims abstract description 8
- 235000021355 Stearic acid Nutrition 0.000 claims abstract description 7
- 239000011230 binding agent Substances 0.000 claims abstract description 7
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 claims abstract description 7
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 claims abstract description 7
- 238000004806 packaging method and process Methods 0.000 claims abstract description 7
- 239000008117 stearic acid Substances 0.000 claims abstract description 7
- 239000000463 material Substances 0.000 claims description 30
- 239000002245 particle Substances 0.000 claims description 18
- 239000003826 tablet Substances 0.000 claims description 15
- 239000008187 granular material Substances 0.000 claims description 12
- 238000003756 stirring Methods 0.000 claims description 12
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims description 9
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 6
- 229910052782 aluminium Inorganic materials 0.000 claims description 6
- 238000001704 evaporation Methods 0.000 claims description 6
- 230000008020 evaporation Effects 0.000 claims description 6
- 239000011888 foil Substances 0.000 claims description 6
- 235000013305 food Nutrition 0.000 claims description 6
- 238000010438 heat treatment Methods 0.000 claims description 6
- 238000005507 spraying Methods 0.000 claims description 6
- 239000012141 concentrate Substances 0.000 claims description 4
- 230000008569 process Effects 0.000 claims description 4
- 240000008790 Musa x paradisiaca Species 0.000 claims description 3
- 235000021015 bananas Nutrition 0.000 claims description 3
- 235000020413 lychee juice Nutrition 0.000 claims description 3
- 235000015206 pear juice Nutrition 0.000 claims description 3
- 240000000111 Saccharum officinarum Species 0.000 claims description 2
- 235000007201 Saccharum officinarum Nutrition 0.000 claims description 2
- 238000001694 spray drying Methods 0.000 claims description 2
- 230000000968 intestinal effect Effects 0.000 abstract description 8
- 229930006000 Sucrose Natural products 0.000 abstract description 6
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract description 6
- 239000003814 drug Substances 0.000 abstract description 6
- 239000005720 sucrose Substances 0.000 abstract description 6
- 101100381997 Danio rerio tbc1d32 gene Proteins 0.000 abstract description 3
- 101100381999 Mus musculus Tbc1d32 gene Proteins 0.000 abstract description 3
- 239000000427 antigen Substances 0.000 abstract description 2
- 102000036639 antigens Human genes 0.000 abstract description 2
- 108091007433 antigens Proteins 0.000 abstract description 2
- 230000000694 effects Effects 0.000 abstract description 2
- 238000005457 optimization Methods 0.000 abstract description 2
- 230000028993 immune response Effects 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 description 5
- 235000013312 flour Nutrition 0.000 description 4
- 239000006041 probiotic Substances 0.000 description 4
- 235000018291 probiotics Nutrition 0.000 description 4
- 210000004027 cell Anatomy 0.000 description 3
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 2
- 230000001055 chewing effect Effects 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 210000000936 intestine Anatomy 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 230000035764 nutrition Effects 0.000 description 2
- 241000186016 Bifidobacterium bifidum Species 0.000 description 1
- 206010008190 Cerebrovascular accident Diseases 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 208000005156 Dehydration Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000002538 fungal effect Effects 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 230000007661 gastrointestinal function Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000008105 immune reaction Effects 0.000 description 1
- 230000005847 immunogenicity Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 244000000010 microbial pathogen Species 0.000 description 1
- 210000000214 mouth Anatomy 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000008855 peristalsis Effects 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Medicinal Preparation (AREA)
Abstract
The present invention relates to the preparation method of a kind of beneficial bacteria factor composite chewable tablet, comprise the following steps: S1, prepare beneficial bacteria factor complex: in hemicellulase liquid, be directly added into Rhizoma amorphophalli powder in a reservoir, addition is the 1/10~1/8 of the volume of hemicellulase liquid, after being sufficiently stirred for, sequentially pass through filtration, be concentrated in vacuo, the technique that is spray-dried prepares beneficial bacteria factor complex;S2, dispensing: carry out dispensing by following weight portion: beneficial bacteria factor complex: 100~120 parts, binding agent 30~45 parts, sucrose: 12~16 parts, oatmeal: 20~30 parts, citric acid: 1~5 part, stearic acid: 2~4 parts;S3, mix and blend;S4, make soft material;S5, tabletting;S6, low-temperature bake;S7, packaging.It is an advantage of the current invention that: intestinal microecology system can play the effect of optimization, may act as immuno-stimulator, improve medicine or antigen immune response ability, after adding fruit juice, taste enriches, and has preferable mouthfeel after Herba bromi japonici compatibility.
Description
Technical field
The present invention relates to the preparation method of chewable tablet, the preparation method of a kind of beneficial bacteria factor composite chewable tablet.
Background technology
Chewable tablet refers to chew or suck the tablet that clothes make sheet swallow after dissolving in oral cavity, is commonly incorporated into sucrose, Oleum menthae etc.
Sweeting agent and flavorant adjust taste, and through chewing, rear surface is long-pending to increase tablet, can promote medicine dissolving in vivo and absorption.
Taking convenience, can swallow, chew containing sucking or taking after water-dispersible.Through chewing, rear surface is long-pending to increase tablet, can promote that medicine exists
Even if internal dissolving and absorption it is also ensured that take medicine on time, are especially suitable for old man, child, apoplexy trouble under exsiccosis
Person, swallow difficulty and gastrointestinal function difference patient, it is possible to reduce medicine to gastrointestinal bear.Therefore chewable tablet is disappeared by vast
The welcome of the person of expense.
But, nowadays rhythm of life is accelerated, and can not take out time motion, how could realize effective absorption of nutrition?
Threpsology expert thinks: only puts into by nutrition and can not solve problem, for the practical situation of contemporary people, improves the suction of intestinal
Receipts ability is a good method, and beneficial bacteria factor is to promote the factor of probiotics propagation in human body, and it is to health, Nai Zhiying
The absorption supported is most important.
Summary of the invention
It is an object of the invention to overcome the shortcoming of prior art, it is provided that the preparation side of a kind of beneficial bacteria factor composite chewable tablet
Method, can play the effect of optimization to intestinal microecology system, may act as immuno-stimulator, improves medicine or antigen immune should
Answering ability, after adding fruit juice, taste enriches, and has preferable mouthfeel after Herba bromi japonici compatibility.
The purpose of the present invention is achieved through the following technical solutions: the preparation method of a kind of beneficial bacteria factor composite chewable tablet,
Comprise the following steps:
S1, prepare beneficial bacteria factor complex: contain a certain amount of hemicellulase liquid in a reservoir, then in hemicellulase liquid
Being directly added into Rhizoma amorphophalli powder, addition is the 1/10~1/8 of the volume of hemicellulase liquid, after being sufficiently stirred for, sequentially pass through filtration,
The technique be concentrated in vacuo, being spray-dried prepares beneficial bacteria factor complex;
S2, dispensing: carry out dispensing by following weight portion: beneficial bacteria factor complex: 100~120 parts, binding agent 30~45 parts, sugarcane
Sugar: 12~16 parts, oatmeal: 20~30 parts, citric acid: 1~5 part, stearic acid: 2~4 parts;
S3, mix and blend: after being sufficiently stirred for by the material of above-mentioned weight portion, cross 100 mesh sieves, remove oarse-grained material;
S4, make soft material: stirring the mixed material after filtering are put into container, then in container, adds fruit juice, stir,
Every 40g mixed material adds fruit juice 2~6ml, obtains soft material;
S5, tabletting: carrying out tabletting in the soft material obtained in step S4 is added tablet machine, indoor temperature is 20~25 DEG C, relatively
Humidity is 40~50%, and to control tablet machine pressure be 250~300kg/cm2, obtain sheet-like particle;
S6, low-temperature bake: spread out by the sheet-like particle obtained in step S5, be placed in baking oven, at 40~50 DEG C toast 40~
50min, takes out when the moisture to sheet-like particle is 1~3%, obtains chewable tablet granule;
S7, packaging: chewable tablet granule employing food stage aluminum foil package material is packed.
In step S1, comprising the concrete steps that of described filtration: the liquid obtained through enzymolysis is crossed 200~400 mesh sieves.
In step S1, described be concentrated in vacuo comprise the concrete steps that: vacuum concentration equipment will be loaded through the liquid filtered
In, controlling vacuum is 60~90kPa, and heating evaporation concentrates, and to control temperature be 45~60 DEG C, obtains paste.
In step S1, comprising the concrete steps that of described spray drying: will put in baking oven through the paste being concentrated in vacuo,
Controlling temperature is 60~70 DEG C, toasts 20~30min, simultaneously in baking process, at interval of 3~5 minutes to paste surface
Carry out spraying treatment.
In step S4, described fruit juice is in Sucus Mali pumilae, Fructus Citri tangerinae juice, bananas juice, Lychee juice, Fructus psidii guajavae immaturus juice, pear juice
Kind.
The invention have the advantages that
1, the beneficial bacteria factor complex of the present invention carries out enzymolysis by hemicellulase liquid to Rhizoma amorphophalli powder, and passes through series of physical
Effect obtains, and not by the digested absorption of human body intestines and stomach, is directly entered large intestine, and highly selective gives bacillus bifidus etc. in intestinal
Probiotics provides culture matrix, stimulates rapidly probiotics amount reproduction, improves probiotics vigor, improve intestine microenvironment,
Improve every physiological function comprehensively, be preferentially combined with the receptor of human body intestinal canal cell surface, prevent pathogenic microorganism to animal body
The adhesion of intestinal mucosal epithelial, it is achieved the eliminating of pathogenetic bacteria.
2, after taking the chewable tablet of beneficial bacteria factor complex, intestinal peristalsis promoting can be stimulated, improve function of intestinal canal, increase feces wet
Spend and keep certain osmotic pressure, thus prevent the generation of constipation.
3, Oligomeric manna sugar has an immunogenicity, effective stimulus immunne response, and can be with toxin, virus and fungal cell
Surface combine, strengthen cell and humoral immune reaction, fungi-proofing disease-resistant.
4, the chewable tablet of the present invention is also added into Herba bromi japonici and fruit juice, can be different according to the fruit juice kind added, and obtains difference
The chewable tablet of taste, rich in taste, with oatmeal compatibility, further improves the mouthfeel of chewable tablet, by consumers in general's
Welcome.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further described, but protection scope of the present invention is not limited to following institute
State.
[embodiment 1]:
The preparation method of a kind of beneficial bacteria factor composite chewable tablet, comprises the following steps:
S1, prepare beneficial bacteria factor complex: contain a certain amount of hemicellulase liquid in a reservoir, then in hemicellulase liquid
Being directly added into Rhizoma amorphophalli powder, addition is the 1/8 of the volume of hemicellulase liquid, after being sufficiently stirred for, sequentially passes through filtration, vacuum dense
Contracting, the technique being spray-dried prepare beneficial bacteria factor complex, the liquid obtained through enzymolysis is crossed 400 mesh sieves, will pass through
The liquid filtered loads in vacuum concentration equipment, and controls vacuum is 60kPa, heating evaporation concentration, and to control temperature be 60 DEG C,
Obtaining paste, will put in baking oven through the paste being concentrated in vacuo, controlling temperature is 60 DEG C, toasts 30min, is drying simultaneously
During Kao, at interval of 5 minutes, paste surface is carried out spraying treatment;
S2, dispensing: carry out dispensing by following weight portion: beneficial bacteria factor complex: 120 parts, binding agent 30 parts, sucrose: 16 parts, swallow
Flour: 30 parts, citric acid: 1 part, stearic acid: 4 parts;
S3, mix and blend: after being sufficiently stirred for by the material of above-mentioned weight portion, cross 100 mesh sieves, remove oarse-grained material;
S4, make soft material: stirring the mixed material after filtering are put into container, then in container, adds fruit juice, described fruit
Juice is Sucus Mali pumilae, stirs, and every 40g mixed material adds fruit juice 6ml, obtains soft material;
S5, tabletting: carrying out tabletting in the soft material obtained in step S4 is added tablet machine, indoor temperature is 25 DEG C, relative humidity
It is 50%, and to control tablet machine pressure be 250kg/cm2, obtain sheet-like particle;
S6, low-temperature bake: spread out by the sheet-like particle obtained in step S5, be placed in baking oven, toasts 40min, extremely at 50 DEG C
Take out when the moisture of sheet-like particle is 3%, obtain chewable tablet granule;
S7, packaging: chewable tablet granule employing food stage aluminum foil package material is packed.
[embodiment 2]:
The preparation method of a kind of beneficial bacteria factor composite chewable tablet, comprises the following steps:
S1, prepare beneficial bacteria factor complex: contain a certain amount of hemicellulase liquid in a reservoir, then in hemicellulase liquid
Being directly added into Rhizoma amorphophalli powder, addition is the 1/9 of the volume of hemicellulase liquid, after being sufficiently stirred for, sequentially passes through filtration, vacuum dense
Contracting, the technique being spray-dried prepare beneficial bacteria factor complex, the liquid obtained through enzymolysis is crossed 300 mesh sieves, will pass through
The liquid filtered loads in vacuum concentration equipment, and controls vacuum is 70kPa, heating evaporation concentration, and to control temperature be 50 DEG C,
Obtaining paste, will put in baking oven through the paste being concentrated in vacuo, controlling temperature is 65 DEG C, toasts 25min, is drying simultaneously
During Kao, at interval of 4 minutes, paste surface is carried out spraying treatment;
S2, dispensing: carry out dispensing by following weight portion: beneficial bacteria factor complex: 110 parts, binding agent 40 parts, sucrose: 14 parts, swallow
Flour: 25 parts, citric acid: 3 parts, stearic acid: 3 parts;
S3, mix and blend: after being sufficiently stirred for by the material of above-mentioned weight portion, cross 100 mesh sieves, remove oarse-grained material;
S4, make soft material: stirring the mixed material after filtering are put into container, then in container, adds fruit juice, described fruit
Juice is Fructus Citri tangerinae juice, stirs, and every 40g mixed material adds fruit juice 4ml, obtains soft material;
S5, tabletting: carrying out tabletting in the soft material obtained in step S4 is added tablet machine, indoor temperature is 22 DEG C, relative humidity
It is 45%, and to control tablet machine pressure be 280kg/cm2, obtain sheet-like particle;
S6, low-temperature bake: spread out by the sheet-like particle obtained in step S5, be placed in baking oven, toasts 45min, extremely at 45 DEG C
Take out when the moisture of sheet-like particle is 2%, obtain chewable tablet granule;
S7, packaging: chewable tablet granule employing food stage aluminum foil package material is packed
[embodiment 3]:
The preparation method of a kind of beneficial bacteria factor composite chewable tablet, comprises the following steps:
S1, prepare beneficial bacteria factor complex: contain a certain amount of hemicellulase liquid in a reservoir, then in hemicellulase liquid
Being directly added into Rhizoma amorphophalli powder, addition is the 1/10 of the volume of hemicellulase liquid, after being sufficiently stirred for, sequentially passes through filtration, vacuum
The technique concentrate, being spray-dried prepares beneficial bacteria factor complex, and the liquid obtained through enzymolysis is crossed 280 mesh sieves, will be through
The liquid filtered loads in vacuum concentration equipment, and controls vacuum is 80kPa, heating evaporation concentration, and to control temperature be 52
DEG C, obtain paste, will put in baking oven through the paste being concentrated in vacuo, controlling temperature is 66 DEG C, toasts 24min, simultaneously
In baking process, at interval of 4 minutes, paste surface is carried out spraying treatment;
S2, dispensing: carry out dispensing by following weight portion: beneficial bacteria factor complex: 112 parts, binding agent 35 parts, sucrose: 15 parts, swallow
Flour: 23 parts, citric acid: 4 parts, stearic acid: 2 parts;
S3, mix and blend: after being sufficiently stirred for by the material of above-mentioned weight portion, cross 100 mesh sieves, remove oarse-grained material;
S4, make soft material: stirring the mixed material after filtering are put into container, then in container, adds fruit juice, described fruit
Juice is bananas juice or Lychee juice, stirs, and every 40g mixed material adds fruit juice 5ml, obtains soft material;
S5, tabletting: carrying out tabletting in the soft material obtained in step S4 is added tablet machine, indoor temperature is 23 DEG C, relative humidity
It is 46%, and to control tablet machine pressure be 280kg/cm2, obtain sheet-like particle;
S6, low-temperature bake: spread out by the sheet-like particle obtained in step S5, be placed in baking oven, toasts 45min, extremely at 45 DEG C
Take out when the moisture of sheet-like particle is 2%, obtain chewable tablet granule;
S7, packaging: chewable tablet granule employing food stage aluminum foil package material is packed.
[embodiment 4]:
The preparation method of a kind of beneficial bacteria factor composite chewable tablet, comprises the following steps:
S1, prepare beneficial bacteria factor complex: contain a certain amount of hemicellulase liquid in a reservoir, then in hemicellulase liquid
Being directly added into Rhizoma amorphophalli powder, addition is the 1/10 of the volume of hemicellulase liquid, after being sufficiently stirred for, sequentially passes through filtration, vacuum
The technique concentrate, being spray-dried prepares beneficial bacteria factor complex, and the liquid obtained through enzymolysis is crossed 200 mesh sieves, will be through
The liquid filtered loads in vacuum concentration equipment, and controls vacuum is 90kPa, heating evaporation concentration, and to control temperature be 45
DEG C, obtain paste, will put in baking oven through the paste being concentrated in vacuo, controlling temperature is 70 DEG C, toasts 20min, simultaneously
In baking process, at interval of 3~5 minutes, paste surface is carried out spraying treatment;
S2, dispensing: carry out dispensing by following weight portion: beneficial bacteria factor complex: 100 parts, binding agent 45 parts, sucrose: 12 parts, swallow
Flour: 20 parts, citric acid: 5 parts, stearic acid: 2 parts;
S3, mix and blend: after being sufficiently stirred for by the material of above-mentioned weight portion, cross 100 mesh sieves, remove oarse-grained material;
S4, make soft material: stirring the mixed material after filtering are put into container, then in container, adds fruit juice, described fruit
Juice is Fructus psidii guajavae immaturus juice or pear juice, stirs, and every 40g mixed material adds fruit juice 2ml, obtains soft material;
S5, tabletting: carrying out tabletting in the soft material obtained in step S4 is added tablet machine, indoor temperature is 20 DEG C, relative humidity
It is 40%, and to control tablet machine pressure be 300kg/cm2, obtain sheet-like particle;
S6, low-temperature bake: spread out by the sheet-like particle obtained in step S5, be placed in baking oven, toasts 50min, extremely at 40 DEG C
Take out when the moisture of sheet-like particle is 1%, obtain chewable tablet granule;
S7, packaging: chewable tablet granule employing food stage aluminum foil package material is packed.
Claims (5)
1. the preparation method of a beneficial bacteria factor composite chewable tablet, it is characterised in that: comprise the following steps:
S1, prepare beneficial bacteria factor complex: contain a certain amount of hemicellulase liquid in a reservoir, then in hemicellulase liquid
Being directly added into Rhizoma amorphophalli powder, addition is the 1/10~1/8 of the volume of hemicellulase liquid, after being sufficiently stirred for, sequentially pass through filtration,
The technique be concentrated in vacuo, being spray-dried prepares beneficial bacteria factor complex;
S2, dispensing: carry out dispensing by following weight portion: beneficial bacteria factor complex: 100~120 parts, binding agent 30~45 parts, sugarcane
Sugar: 12~16 parts, oatmeal: 20~30 parts, citric acid: 1~5 part, stearic acid: 2~4 parts;
S3, mix and blend: after being sufficiently stirred for by the material of above-mentioned weight portion, cross 100 mesh sieves, remove oarse-grained material;
S4, make soft material: stirring the mixed material after filtering are put into container, then in container, adds fruit juice, stir,
Every 40g mixed material adds fruit juice 2~6ml, obtains soft material;
S5, tabletting: carrying out tabletting in the soft material obtained in step S4 is added tablet machine, indoor temperature is 20~25 DEG C, relatively
Humidity is 40~50%, and to control tablet machine pressure be 250~300kg/cm2, obtain sheet-like particle;
S6, low-temperature bake: spread out by the sheet-like particle obtained in step S5, be placed in baking oven, at 40~50 DEG C toast 40~
50min, takes out when the moisture to sheet-like particle is 1~3%, obtains chewable tablet granule;
S7, packaging: chewable tablet granule employing food stage aluminum foil package material is packed.
The preparation method of a kind of beneficial bacteria factor composite chewable tablet the most according to claim 1, it is characterised in that: step S1
In, comprising the concrete steps that of described filtration: the liquid obtained through enzymolysis is crossed 200~400 mesh sieves.
The preparation method of a kind of beneficial bacteria factor composite chewable tablet the most according to claim 2, it is characterised in that: step S1
In, described be concentrated in vacuo comprise the concrete steps that: will load in vacuum concentration equipment through the liquid filtered, controlling vacuum is
60~90kPa, heating evaporation concentrates, and to control temperature be 45~60 DEG C, obtains paste.
The preparation method of a kind of beneficial bacteria factor composite chewable tablet the most according to claim 3, it is characterised in that: step S1
In, comprising the concrete steps that of described spray drying: will put in baking oven through the paste that is concentrated in vacuo, control temperature be 60~
70 DEG C, toast 20~30min, simultaneously in baking process, at interval of 3~5 minutes, paste surface is carried out spraying treatment.
The preparation method of a kind of beneficial bacteria factor composite chewable tablet the most according to claim 1, it is characterised in that: step S4
In, described fruit juice is the one in Sucus Mali pumilae, Fructus Citri tangerinae juice, bananas juice, Lychee juice, Fructus psidii guajavae immaturus juice, pear juice.
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Cited By (1)
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---|---|---|---|---|
CN109832334A (en) * | 2017-11-28 | 2019-06-04 | 东阿阿胶股份有限公司 | A kind of donkey milk piece of strengthen immunity and preparation method thereof |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1904059A (en) * | 2006-05-29 | 2007-01-31 | 湖北广华生物有限公司 | Production method of konjak mannose using cellulase |
CN101816386A (en) * | 2010-04-07 | 2010-09-01 | 云南富源金田原农产品开发有限责任公司 | Konjak oligosaccharide buccal tablets |
CN105614897A (en) * | 2016-01-29 | 2016-06-01 | 福建农林大学 | Konjac glucomannan, strawberry and vitamin C chewable tablet and method for preparing same |
-
2016
- 2016-06-30 CN CN201610499407.2A patent/CN106136232A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1904059A (en) * | 2006-05-29 | 2007-01-31 | 湖北广华生物有限公司 | Production method of konjak mannose using cellulase |
CN101816386A (en) * | 2010-04-07 | 2010-09-01 | 云南富源金田原农产品开发有限责任公司 | Konjak oligosaccharide buccal tablets |
CN105614897A (en) * | 2016-01-29 | 2016-06-01 | 福建农林大学 | Konjac glucomannan, strawberry and vitamin C chewable tablet and method for preparing same |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109832334A (en) * | 2017-11-28 | 2019-06-04 | 东阿阿胶股份有限公司 | A kind of donkey milk piece of strengthen immunity and preparation method thereof |
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