CN106109055B - 一种血管覆膜支架制作方法 - Google Patents

一种血管覆膜支架制作方法 Download PDF

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CN106109055B
CN106109055B CN201610577365.XA CN201610577365A CN106109055B CN 106109055 B CN106109055 B CN 106109055B CN 201610577365 A CN201610577365 A CN 201610577365A CN 106109055 B CN106109055 B CN 106109055B
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bracket
blood vessel
tubing
covered stent
production method
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CN106109055A (zh
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马英祥
姜晓筑
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Beijing Taijieweiye Technology Co.,Ltd.
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Chengdu Jiabaoxiang Biological Technology Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2/07—Stent-grafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/0077—Special surfaces of prostheses, e.g. for improving ingrowth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2/07—Stent-grafts
    • A61F2002/072—Encapsulated stents, e.g. wire or whole stent embedded in lining
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2240/001—Designing or manufacturing processes
    • A61F2240/002—Designing or making customized prostheses

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Prostheses (AREA)

Abstract

本发明公开了一种血管覆膜支架制作方法，其特征在于，包括以下步骤：a.在管材上通过激光切割的方式形成沿所述管材的轴向依次切割出的多个圆锥型薄壁环，并制造出用于连接相邻两个外撑柱的连接挂钩或连接筋；b.利用镍钛合金编织成金属丝，且金属丝外表面镀上氮化钛材料屏蔽层，再制成含有多个波峰和多个波谷的波浪状上网架和下网架，且将上网架和下网架置于薄壁环内；c.对b步骤后得到的支架进行退火处理，以除去在所述激光切割时产生的残余应力；d.对c步骤得到的支架采用电化学抛光机进行抛光，再在支架外包裹覆膜。采用本发明有效提高覆膜支架的稳定性和可靠性。

Description

一种血管覆膜支架制作方法
技术领域
本发明涉及激光切割领域，具体而言，是一种血管覆膜支架制作方法。
背景技术
动脉瘤是临床上十分凶险的一种血管疾病，因此，一经发现动脉瘤患者，应尽快对其进行相应治疗。目前，利用采用的是利用管径较细的输送系统，将被压缩状态的覆膜支架送达病变血管的位置后准确释放，覆盖在病变血管段，隔绝瘤腔并形成新的血流通道；动脉瘤在丧失血液供应后，瘤腔内残留血液逐渐形成血栓并肌化成血管组织，扩张状态的瘤壁因受负压而收缩，逐渐恢复到接近原始形态，从而达到治疗动脉瘤的目的。这一技术大大减轻了手术创伤，患者恢复较快。然而，在治疗过程中，现有覆膜支架释放后容易被强制性弯折变形，使覆膜支架与血管壁或瘤颈的贴壁性能变差，容易导致覆膜支架移位与内漏。而采用镍钛合金材料制作的骨架，虽然也在一定程度上提高了支架的稳固能力，但其镍离子在人体内释放后，长期堆积容易引起炎症和血栓。
发明内容
本发明旨在提供一种血管覆膜支架制作方法，以解决上述问题。
为实现上述目的，本发明的技术方案如下：
一种血管覆膜支架制作方法，其特征在于，包括以下步骤：
a. 在管材上通过激光切割的方式形成沿所述管材的轴向依次切割出的多个圆锥型薄壁环，并制造出用于连接相邻两个外撑柱的连接挂钩或连接筋；
b.利用镍钛合金编织成金属丝，且金属丝外表面镀上氮化钛材料屏蔽层，再制成含有多个波峰和多个波谷的波浪状上网架和下网架，且将上网架和下网架置于薄壁环内；
c.对b步骤后得到的支架进行退火处理，以除去在所述激光切割时产生的残余应力；
d.对c步骤得到的支架采用电化学抛光机进行抛光，再在支架外包裹覆膜。
进一步地，所述步骤a中的管材直径为1mm。
本发明的有益效果在于：采用本发明提高径向支撑力的同时，金属覆盖率也会增加，覆膜支架单元依次套接设置，使覆膜支架的方向性降低，能够提高覆膜支架的弯曲或设置灵活性，从而能够使覆膜支架更好地与血管壁或瘤颈相适配，避免形成内漏。
具体实施方式
下面具体实施例对本发明做进一步说明。
一种血管覆膜支架制作方法，其特征在于，包括以下步骤：
a. 在直径为1mm管材上通过激光切割的方式形成沿所述管材的轴向依次切割出的多个圆锥型薄壁环，并制造出用于连接相邻两个外撑柱的连接挂钩或连接筋；
b.利用镍钛合金编织成金属丝，且金属丝外表面镀上氮化钛材料屏蔽层，再制成含有多个波峰和多个波谷的波浪状上网架和下网架，且将上网架和下网架置于薄壁环内；
c.对b步骤后得到的支架进行退火处理，以除去在所述激光切割时产生的残余应力；
d.对c步骤得到的支架采用电化学抛光机进行抛光，再在支架外包裹覆膜。
采用本发明提高径向支撑力的同时，金属覆盖率也会增加，覆膜支架单元依次套接设置，使覆膜支架的方向性降低，能够提高覆膜支架的弯曲或设置灵活性，从而能够使覆膜支架更好地与血管壁或瘤颈相适配，避免形成内漏。
以上所述仅为本发明的优选实施例而已，并不用于限制本发明，对于本领域的技术人员来说，本发明可以有各种更改和变化。凡在本发明的精神和原则之内，所作的任何修改、等同替换、改进等，均应包含在本发明的保护范围之内。

Claims (2)

1.一种血管覆膜支架制作方法，其特征在于，包括以下步骤：
a. 在管材上通过激光切割的方式形成沿所述管材的轴向依次切割出的多个圆锥型薄壁环，并制造出用于连接相邻两个外撑柱的连接挂钩或连接筋；
b.利用镍钛合金编织成金属丝，且金属丝外表面镀上氮化钛材料屏蔽层，再制成含有多个波峰和多个波谷的波浪状上网架和下网架，且将上网架和下网架置于薄壁环内；
c.对b步骤后得到的支架进行退火处理，以除去在所述激光切割时产生的残余应力；
d.对c步骤得到的支架采用电化学抛光机进行抛光，再在支架外包裹覆膜。
2.根据权利要求1所述的血管覆膜支架制作方法，其特征在于，所述步骤a中的管材直径为1mm。
CN201610577365.XA 2016-07-21 2016-07-21 一种血管覆膜支架制作方法 Active CN106109055B (zh)

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CN111659000A (zh) * 2020-06-30 2020-09-15 华东师范大学 一种中空金属微针和中空金属微针阵列及其制备方法
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CN201438978U (zh) * 2009-07-03 2010-04-21 先健科技(深圳)有限公司 血管覆膜支架
CN104706448A (zh) * 2015-03-26 2015-06-17 湖南埃普特医疗器械有限公司 覆膜支架以及覆膜支架用输送系统

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AU2007227000A1 (en) * 2006-03-20 2007-09-27 Xtent, Inc. Apparatus and methods for deployment of linked prosthetic segments
US9180030B2 (en) * 2007-12-26 2015-11-10 Cook Medical Technologies Llc Low profile non-symmetrical stent

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CN201438978U (zh) * 2009-07-03 2010-04-21 先健科技(深圳)有限公司 血管覆膜支架
CN104706448A (zh) * 2015-03-26 2015-06-17 湖南埃普特医疗器械有限公司 覆膜支架以及覆膜支架用输送系统

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