CN106106920A - A kind of effervescent tablet for slimming herbal tea and preparation method thereof - Google Patents
A kind of effervescent tablet for slimming herbal tea and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a kind of effervescent tablet for slimming herbal tea, including following components: the common extract of Chinese herbal medicine 10 16 parts, laminarin 6 10 parts and citrus pectin 48 parts, raspberry extract 46 parts and agar 30 40 parts；Wherein, the common extract of described Chinese herbal medicine is obtained by Exocarpium Citrulli 20 30 parts, 10 25 parts of Folium Mori, Fructus Crataegi 18 26 parts, Radix Polygoni Multiflori 46 parts, Pericarpium Citri Reticulatae 8 15 parts and 16 30 parts of common extractions of Poria.Present invention adds laminarin and citrus pectin, laminarin has good fat-reducing effect, it is possible to take out of external by the fat in chyme, thus reduces body to the fat absorption in food.The present invention is also added into raspberry extract, containing various active material, anthocyanidin, phenol and organic acid class etc., has extremely strong non-oxidizability, removes interior free yl, and can effectively reduce lipids contents, lipid metabolism in acceleration bodies.
Description
Technical field
The invention belongs to Chinese herbal and crude drugs preparations and native compound extractive technique field, be specifically related to a kind of effervescent tablet for slimming cool
Tea, the invention still further relates to the preparation method of a kind of effervescent tablet for slimming herbal tea.
Background technology
At present, the plant cold tea of the Medicine Food Homology that antipyretic beverage has no side effect the most safely, increasingly by people's
Favor.From these literature existing to, many Chinese herbal medicine can make herbal tea, and these herbal tea are the life side of adding of people
Just, but the weak point existed is that the composition having is more and complicated process of preparation.
Along with scale, the diversification in herbal tea market, single heat-clearing and detoxifying herbal tea can not meet most demand.When
The front overweight and fat health problem worldwide presenting quickly growth, and if the appearance of this health problem
Not being controlled by, it can bring again the serious diseases such as more complicated cardiovascular and cerebrovascular vessel；It addition, modern youngster is for ' bony
Beautiful ' pursuit, allow ' fat-reducing ' this topic be discussed warmly always.So, according to people to healthy and aesthetic two big demands, fat-reducing
Market can be actively catered in the release of herbal tea, and brings the agitation of one health slimming.
On market, herbal tea uses canned or bottled mostly, and the herbal tea of this kind of form is drunk conveniently, is suitable for major part occasion.But
Being to be not appropriate for for long-distance travel or the crowd that goes on business, that goes away typically cannot carry overweight beverage type article, typically
Can select the most repeatedly to buy, once be difficult on the way obtain, or herbal tea selling at exorbitant prices, then just directly contribute
The crowd drinking specific herbal tea is needed to be difficult to meet self needs.In addition, long-distance trip natively can bring labor to health
Tired or uncomfortable, need to drink the health-related beverages such as herbal tea.Therefore, Vehicles Collected from Market needs one be convenient for carrying, Instant Drinks quick
Herbal tea product.
Effervescent tablet is a kind of tablet containing gas-producing disintegrant.So-called gas-producing disintegrant be typically organic acid and sodium carbonate,
The mixture of sodium bicarbonate (sodium bicarbonate)；Effervescent tablet itself is dried moisture-free, and two kinds of materials in gas-producing disintegrant are unionized
Can not react；But after effervescent tablet is put in water, two kinds of material generation acid-base reactions, produce great amount of carbon dioxide, make
The rapid disintegrate of tablet and thawing, the bubble that disintegrate sometimes produces also can make tablet roll up and down in water, accelerates its disintegrate and melt
Change.The carbon dioxide produced during disintegration of tablet is partially dissolved in drinking-water, makes drinking-water have the aesthetic feeling as soda pop when drinking in entrance.Bubble
The beverage rising tablet preparation is highly convenient for carrying, and Instant Drinks mouthfeel is unique, is liked by the current young consumer group.Especially in inflammation
In the summer of heat, the mouthfeel after effervescent tablet punching is released is dispersed extremely hot and unhappy, will bring one agitation of the new beverage of herbal tea.
Summary of the invention
It is an object of the invention to provide a kind of effervescent tablet for slimming herbal tea, in order to meet people currently to healthy beautiful pursuit,
And enrich current herbal tea market.
It is a further object of the present invention to provide the preparation method of a kind of effervescent tablet for slimming herbal tea.
First technical scheme of the present invention is, a kind of effervescent tablet for slimming herbal tea, according to mass parts (in terms of butt)
Including following components: Chinese herbal medicine common extract 10-16 part, laminarin 6-10 part and citrus pectin 4-8 part, Fructus Rubi is extracted
Thing 4-6 part；Wherein, the common extract of described Chinese herbal medicine by Exocarpium Citrulli 20-30 part, Folium Mori 10-25 part, Fructus Crataegi 18-26 part, what
Radix Polygoni Multiflori 4-6 part, Pericarpium Citri Reticulatae 8-15 part and Poria 16-30 part are jointly extracted and are obtained.
In technique scheme:
The preparation method of described laminarin is: Thallus Laminariae (Thallus Eckloniae) is dried powder process, adds water and is stirred continuously, and will wherein add cellulase afterwards
And protease, heating in water bath carries out ultrasonic Treatment after being stirred continuously；The enzymolysis solution obtained is centrifuged, concentrates and lyophilizing, standby
With.
Further, the concrete preparation method of above-mentioned laminarin is: taking Thallus Laminariae (Thallus Eckloniae) and be dried, grinding flour sieves, and adds water and makes
Its solid-liquid ratio is 1:25-35, and is stirred continuously, and is 2-3:1 by wherein adding the mass ratio that mass fraction is 0.2-0.5% afterwards
Cellulase: protease, in 55-65 DEG C of heating in water bath and after being stirred continuously 30-40min, then carry out ultrasonic Treatment；Finally
The enzymolysis solution obtained is centrifuged, concentrates and lyophilizing, standby.
Further, before above-mentioned addition enzyme, first Thallus Laminariae (Thallus Eckloniae) liquid being carried out microwave radiation, microwave power is preferably
600W。
Further, the preparation method of above-mentioned citrus pectin is: added water by fresh Fericarpium Citri Limoniae, regulates pH, in water-bath and
Extract under Ultrasonic Conditions, then add alcohol precipitation, finally the precipitated liquid obtained is centrifuged, concentrates and lyophilizing, standby.
Further, the concrete preparation method of above-mentioned citrus pectin is: fresh Fericarpium Citri Limoniae is added solid-liquid ratio is 1:50-
The pure water of 60, regulation pH is 0.5-1.5, extracts under 40-45 DEG C of water-bath and Ultrasonic Conditions, and then adding volume ratio is 1:
90% alcohol precipitation of 1, is finally centrifuged the precipitated liquid obtained, concentrates and lyophilizing.
Further, the extracting method of the common extract of described Chinese herbal medicine is: in terms of butt, take Exocarpium Citrulli 20-30 part,
Folium Mori 10-25 part, Fructus Crataegi 18-26 part, Radix Polygoni Multiflori 4-6 part, Pericarpium Citri Reticulatae 8-15 part and Poria 16-30 part, carried out above-mentioned each composition
Pulverize and sieve, and uniformly mix, first above-mentioned mixed powder is carried out microwave treatment, then under Ultrasonic Conditions, add
Enter the ethanol that mass fraction is 15-20% that solid-liquid ratio is 1:22-26 to carry out extracting 2-4h, obtain Chinese herbal medicine alcohol extract,
Then the common water extract of Chinese herbal medicine is obtained by outstanding steaming of vacuum with lyophilizing.
Further, superfine communication technique is taked in above-mentioned pulverizing, is crushed to 0.1-20 μm.
Further, above-mentioned mixed-powder carries out microwave radiation processing 30-35min, and the power of microwave is 700W.
Further, the preparation method of described raspberry extract is: taking the concentration that fresh Fructus Rubi addition solid-liquid ratio is 1:1 is
2-6% ethanol is pulled an oar, and extracts at the ethanol that addition concentration is 10-30% after homogenate, and solid-liquid ratio is 1:10-15,
Microwave radiation 1-2h, adds 95% ethanol that volume is extracting liquid volume 5%, extracts 2-after being sufficiently stirred under Ultrasonic Conditions
4h, centrifugal, take supernatant, concentrate, lyophilizing and get final product.
Second technical scheme of the present invention is, a kind of effervescent tablet for slimming herbal tea preparation method:
(1) weighing polyethylene glycol 6000, add sodium bicarbonate, stir after melting, cooling is ground, and sieving for standby is carbon
Acid hydrogen sodium wrappage granule；
(2) taking the above-mentioned common extract of prepared Chinese herbal medicine, starfish saponin and Stichopus japonicus polysaccharide, addition citric acid, diluent are abundant
Mix homogeneously also sieves；
(3) product after processing that step (1) and step (2) sieved mixes in proportion, and adds binding agent and be sufficiently mixed
Pelletizing, pelletizing press sheet is dried.
Further, the mesh number sieved in described step (1) and step (2) is 20-40 mesh.
Further, the diluent in described step (2) is lactose or alginate jelly.
Further, the binding agent in described step (3) is polyvinylpyrrolidone (PVP) ethanol solution, and its concentration
For 4-12wt%.
Further, adding flavoring agent in described step (2), it is sweeting agent, preferably stevioside.
Further, the mass fraction relation adding each component in described preparation method is: the common extract of Chinese herbal medicine
10-16 part, laminarin 6-10 part and citrus pectin 4-8 part, raspberry extract 4-6 part, sodium bicarbonate 10-25 part, poly-second
Glycol 6000 2-6 part, citric acid 12-24 part, diluent 8-15 part, sweeting agent 0.2-0.4 part, binding agent 0.2-0.6
Part.
Further, ultrasonic Treatment 35min is carried out after described step (3) adding binding agent.
The invention has the beneficial effects as follows: the Chinese herbal medicine of the present invention is selected 6 kinds of medicine-food two-purposes, gentle QI invigorating, effect is mutually auxiliary
Coordinating, conditioning health is able to healthy fat reducing.It addition, the present invention is also added into laminarin and citrus pectin, laminarin has
Good fat-reducing effect, it is possible to the fat in chyme is taken out of external, thus it is to the fat absorption in food and extra large to reduce body
Band polysaccharide also has hypoglycemic health-care effect；Citrus pectin, as water soluble dietary fiber, improves intestinal colony environment, reduces
Intestinal is for the absorption of fat, the accumulation slimmed the abdomen.Raspberry extract prepared by the present invention contains various active material,
Anthocyanidin, phenol and organic acid class etc., have extremely strong non-oxidizability, removes interior free yl, and can effectively reduce blood
Fat content, lipid metabolism in acceleration bodies.The present invention utilizes agar as the main bodies of effervescent tablet, and agar is algae extract,
Inherently there is good health-care effect.Through verification experimental verification, the present invention with the addition of laminarin and citrus pectin, it is possible to effectively
Blood fat reducing and loss of weight, with the addition of raspberry extract, while fat reducing blood sugar lowering, it is provided that good non-oxidizability, makes weight loss procedures more
For health.
Detailed description of the invention
Below in conjunction with detailed description of the invention, the present invention is described in detail.
Embodiment 1
The preparation method of a kind of effervescent tablet for slimming herbal tea is:
(1) weighing polyethylene glycol 6000, add sodium bicarbonate, stir after melting, cooling is ground, and crosses 20 mesh sieves standby, i.e.
For sodium bicarbonate wrappage granule；
(2) take the above-mentioned common extract of prepared Chinese herbal medicine, starfish saponin and Stichopus japonicus polysaccharide, add citric acid, lactose and Flos Chrysanthemi
Glycosides is sufficiently mixed uniformly and sieves；
(3) product after processing that step (1) and step (2) sieved mixes in proportion, and to add concentration be the poly-of 4wt%
Vinylpyrrolidone (PVP) ethanol solution, carries out ultrasonic Treatment 35min, and it is sufficiently mixed granulation, and pelletizing press sheet is dried i.e.
Can.
The mass fraction relation adding each component in described preparation method is: the common extract of Chinese herbal medicine 10 parts, Thallus Laminariae (Thallus Eckloniae) are many
Sugar 6 parts and citrus pectin 4 parts, raspberry extract 4 parts, sodium bicarbonate 10 parts, polyethylene glycol 6000 2 parts, citric acid 12 parts,
Diluent 8 parts, sweeting agent 0.2 part, binding agent 0.2 part.
Wherein, the preparation method of described laminarin is: takes Thallus Laminariae (Thallus Eckloniae) and is dried, and grinding flour crosses 3.5-5.5mm sieve, adds water and makes
Its solid-liquid ratio is 1:25, and is stirred continuously, and will wherein add the cellulose that mass ratio is 2:1 that mass fraction is 0.2% afterwards
Enzyme: protease, first carries out the process 30min that microwave power is 600W, then at 55-65 DEG C of heating in water bath and be stirred continuously 30-
After 40min, then carry out the ultrasonic Treatment of 20-40min；Finally the enzymolysis solution obtained is centrifuged, concentrates and lyophilizing, standby
With.
The preparation method of described citrus pectin is: fresh Fericarpium Citri Limoniae is added solid-liquid ratio is the pure water of 1:50, regulation
PH is 0.5, extracts under 40-45 DEG C of water-bath and Ultrasonic Conditions, then adds 90% ethanol that volume ratio is 1:1 and precipitates
2-4h, is finally centrifuged the precipitated liquid obtained, concentrates and lyophilizing.
The preparation method of described raspberry extract is: take fresh Fructus Rubi adding the concentration that solid-liquid ratio is 1:1 is 2% ethanol
Pulling an oar, extract at the ethanol that addition concentration is 10% after homogenate, solid-liquid ratio is 1:10, and microwave radiation 1h adds
Volume is 95% ethanol of extracting liquid volume 5%, extracts 2-4h after being sufficiently stirred under Ultrasonic Conditions, centrifugal, takes supernatant, dense
Contracting, lyophilizing and get final product.
The preparation method of the common extract of described Chinese herbal medicine is: in terms of butt, takes Exocarpium Citrulli 20 parts, 10 parts of Folium Mori, Fructus Crataegi
18 parts, Radix Polygoni Multiflori 4 parts, Pericarpium Citri Reticulatae 8 parts and 16 parts of Poria, pulverize and sieve above-mentioned each composition, and uniformly mix, first by upper
Stating mixed powder and carry out microwave treatment 30-35min, the power of microwave is 700W, then under Ultrasonic Conditions, adds pan feeding
Liquor ratio is that the ethanol that mass fraction is 15% of 1:22 carries out extracting 2h, obtains Chinese herbal medicine alcohol extract, then passes through vacuum
Outstanding steaming obtains the common water extract of Chinese herbal medicine with lyophilizing.
Embodiment 2
The preparation method of a kind of effervescent tablet for slimming herbal tea is:
(1) weighing polyethylene glycol 6000, add sodium bicarbonate, stir after melting, cooling is ground, and crosses 20 mesh sieves standby, i.e.
For sodium bicarbonate wrappage granule；
(2) take the above-mentioned common extract of prepared Chinese herbal medicine, starfish saponin and Stichopus japonicus polysaccharide, add citric acid, lactose and Flos Chrysanthemi
Glycosides is sufficiently mixed uniformly and sieves；
(3) product after processing that step (1) and step (2) sieved mixes in proportion, and to add concentration be the poly-of 12wt%
Vinylpyrrolidone (PVP) ethanol solution, carries out ultrasonic Treatment 35min, and it is sufficiently mixed granulation, and pelletizing press sheet is dried i.e.
Can.
The mass fraction relation adding each component in described preparation method is: according to mass fraction (in terms of butt), medium-height grass
The common extract of medicine 16 parts, laminarin 10 parts and citrus pectin 8 parts, raspberry extract 6 parts, sodium bicarbonate 25 parts, poly-second
Glycol 6,000 6 parts, citric acid 24 parts, diluent 15 parts, sweeting agent 0.4 part, binding agent 0.6 part.
Wherein, the preparation method of described laminarin is: takes Thallus Laminariae (Thallus Eckloniae) and is dried, and grinding flour crosses 3.5-5.5mm sieve, adds water and makes
Its solid-liquid ratio is 1:35, and is stirred continuously, and will wherein add the cellulose that mass ratio is 3:1 that mass fraction is 0.5% afterwards
Enzyme: protease, first carries out the process 40min that microwave power is 600W, in 55-65 DEG C of heating in water bath and be stirred continuously 30-
After 40min, then carry out the ultrasonic Treatment of 20-40min；Finally the enzymolysis solution obtained is centrifuged, concentrates and lyophilizing, standby
With.
The preparation method of described citrus pectin is: fresh Fericarpium Citri Limoniae is added solid-liquid ratio is the pure water of 1:60, regulation
PH is 1.5, extracts under 40-45 DEG C of water-bath and Ultrasonic Conditions, then adds 90% ethanol that volume ratio is 1:1 and precipitates
2-4h, is finally centrifuged the precipitated liquid obtained, concentrates and lyophilizing.
The preparation method of described raspberry extract is: take fresh Fructus Rubi adding the concentration that solid-liquid ratio is 1:1 is 6% ethanol
Pulling an oar, extract at the ethanol that addition concentration is 30% after homogenate, solid-liquid ratio is 1:15, microwave radiation 2h, then adds
Enter 95% ethanol that volume is extracting liquid volume 5%, under Ultrasonic Conditions, after being sufficiently stirred for, extract 2-4h, centrifugal, take supernatant,
Concentrate, lyophilizing and get final product.
The preparation method of the common extract of described Chinese herbal medicine is: in terms of butt, takes Exocarpium Citrulli 30 parts, 25 parts of Folium Mori, Fructus Crataegi
26 parts, Radix Polygoni Multiflori 6 parts, Pericarpium Citri Reticulatae 15 parts and 30 parts of Poria, pulverize and sieve above-mentioned each composition, and uniformly mix, and first will
Above-mentioned mixed powder carries out microwave treatment 30-35min, and the power of microwave is 700W, then under Ultrasonic Conditions, adds
Solid-liquid ratio is that the ethanol that mass fraction is 20% of 1:26 carries out extracting 4h, obtains Chinese herbal medicine alcohol extract, then by true
Hovering steams and lyophilizing obtains the common water extract of Chinese herbal medicine.
Embodiment 3
The preparation method of a kind of effervescent tablet for slimming herbal tea is:
(1) weighing polyethylene glycol 6000, add sodium bicarbonate, stir after melting, cooling is ground, and crosses 20 mesh sieves standby, i.e.
For sodium bicarbonate wrappage granule；
(2) take the above-mentioned common extract of prepared Chinese herbal medicine, starfish saponin and Stichopus japonicus polysaccharide, add citric acid, lactose and Flos Chrysanthemi
Glycosides is sufficiently mixed uniformly and sieves；
(3) product after processing that step (1) and step (2) sieved mixes in proportion, and to add concentration be the poly-of 12wt%
Vinylpyrrolidone (PVP) ethanol solution, carries out ultrasonic Treatment 35min, and it is sufficiently mixed granulation, and pelletizing press sheet is dried i.e.
Can.
The mass fraction relation adding each component in described preparation method is: according to mass fraction (in terms of butt), medium-height grass
The common extract of medicine 12 parts, laminarin 8 parts and citrus pectin 6 parts, raspberry extract 5 parts, sodium bicarbonate 20 parts, poly-second two
Alcohol 6,000 3 parts, citric acid 20 parts, diluent 12 parts, sweeting agent 0.3 part, binding agent 0.4 part.
Wherein, the preparation method of described laminarin is: takes Thallus Laminariae (Thallus Eckloniae) and is dried, and grinding flour crosses 3.5-5.5mm sieve, adds water and makes
Its solid-liquid ratio is 1:30, and is stirred continuously, and will wherein add the cellulase that mass ratio is 2:1 that mass fraction is 4% afterwards:
Protease, first carries out the process 35min that microwave power is 600W, in 55-65 DEG C of heating in water bath and be stirred continuously 30-40min
After, then carry out the ultrasonic Treatment of 20-40min；Finally the enzymolysis solution obtained is centrifuged, concentrates and lyophilizing, standby.
The preparation method of described citrus pectin is: fresh Fericarpium Citri Limoniae is added solid-liquid ratio is the pure water of 1:55, regulation
PH is 1.0, extracts under 40-45 DEG C of water-bath and Ultrasonic Conditions, then adds 90% ethanol that volume ratio is 1:1 and precipitates
2-4h, is finally centrifuged the precipitated liquid obtained, concentrates and lyophilizing.
The preparation method of described raspberry extract is: take fresh Fructus Rubi adding the concentration that solid-liquid ratio is 1:1 is 3% ethanol
Pulling an oar, extract at the ethanol that addition concentration is 20% after homogenate, solid-liquid ratio is 1:12, microwave radiation 1.5h, then adds
Enter 95% ethanol that volume is extracting liquid volume 5%, under Ultrasonic Conditions, after being sufficiently stirred for, extract 2-4h, centrifugal, take supernatant,
Concentrate, lyophilizing and get final product.
The preparation method of the common extract of described Chinese herbal medicine is: in terms of butt, takes Exocarpium Citrulli 25 parts, 20 parts of Folium Mori, Fructus Crataegi
22 parts, Radix Polygoni Multiflori 5 parts, Pericarpium Citri Reticulatae 12 parts and 24 parts of Poria, pulverize and sieve above-mentioned each composition, and uniformly mix, and first will
Above-mentioned mixed powder carries out microwave treatment 30-35min, and the power of microwave is 700W, then under Ultrasonic Conditions, adds
Solid-liquid ratio is that the ethanol that mass fraction is 20% of 1:23 carries out extracting 3h, obtains Chinese herbal medicine alcohol extract, then by true
Hovering steams and lyophilizing obtains the common water extract of Chinese herbal medicine.
Comparative example 1:
The preparation method of a kind of effervescent tablet for slimming herbal tea is:
(1) weighing polyethylene glycol 6000, add sodium bicarbonate, stir after melting, cooling is ground, and crosses 20 mesh sieves standby, i.e.
For sodium bicarbonate wrappage granule；
(2) take the above-mentioned common extract of prepared Chinese herbal medicine, starfish saponin and Stichopus japonicus polysaccharide, add citric acid, lactose and Flos Chrysanthemi
Glycosides is sufficiently mixed uniformly and sieves；
(3) product after processing that step (1) and step (2) sieved mixes in proportion, and to add concentration be the poly-of 10wt%
Vinylpyrrolidone (PVP) ethanol solution, carries out ultrasonic Treatment 35min, and it is sufficiently mixed granulation, and pelletizing press sheet is dried i.e.
Can.
The mass fraction relation adding each component in described preparation method is: the common extract of Chinese herbal medicine 12 parts, Thallus Laminariae (Thallus Eckloniae) are many
Sugar 8 parts and citrus pectin 7 parts, sodium bicarbonate 20 parts, polyethylene glycol 6000 4 parts, citric acid 20 parts, diluent 15 parts, sweet taste
Agent 0.2 part, binding agent 0.3 part.
Wherein, the concrete preparation method of above-mentioned laminarin is: taking Thallus Laminariae (Thallus Eckloniae) and be dried, grinding flour sieves, and adds water and makes its material
Liquor ratio is 1:25-35, and is stirred continuously, and first Thallus Laminariae (Thallus Eckloniae) liquid is carried out microwave radiation 30min, and microwave power is preferably 600W, afterwards
To wherein add the cellulase that mass ratio is 2-3:1 that mass fraction is 0.2-0.5%: protease, add in 55-65 DEG C of water-bath
Heat after being stirred continuously 30-40min, then carry out ultrasonic Treatment；Finally the enzymolysis solution obtained is centrifuged, concentrates and freezes
Dry, standby.
The concrete preparation method of above-mentioned citrus pectin is: fresh Fericarpium Citri Limoniae is added solid-liquid ratio is the pure water of 1:55,
Regulation pH is 1, extracts under 40-45 DEG C of water-bath and Ultrasonic Conditions, then adds 90% alcohol precipitation that volume ratio is 1:1,
After the precipitated liquid obtained be centrifuged, concentrate and lyophilizing.
The preparation method of the common extract of said herbal medicine is: in terms of butt, takes Exocarpium Citrulli 24 parts, 20 parts of Folium Mori, Fructus Crataegi
22 parts, Radix Polygoni Multiflori 4 parts, Pericarpium Citri Reticulatae 12 parts and 27 parts of Poria, pulverize and sieve above-mentioned each composition, and uniformly mix, and first will
Above-mentioned mixed powder carries out microwave treatment 30-35min, and the power of microwave is 700W, then under Ultrasonic Conditions, adds
Solid-liquid ratio is that the ethanol that mass fraction is 20% of 1:24 carries out extracting 3h, obtains Chinese herbal medicine alcohol extract, then by true
Hovering steams and lyophilizing obtains the common water extract of Chinese herbal medicine.
Comparative example 2:
The preparation method of a kind of effervescent tablet for slimming herbal tea is:
(1) weighing polyethylene glycol 6000, add sodium bicarbonate, stir after melting, cooling is ground, and crosses 20 mesh sieves standby, i.e.
For sodium bicarbonate wrappage granule；
(2) take the above-mentioned common extract of prepared Chinese herbal medicine, starfish saponin and Stichopus japonicus polysaccharide, add citric acid, lactose and Flos Chrysanthemi
Glycosides is sufficiently mixed uniformly and sieves；
(3) product after processing that step (1) and step (2) sieved mixes in proportion, and to add concentration be the poly-of 8wt%
Vinylpyrrolidone (PVP) ethanol solution, carries out ultrasonic Treatment 35min, and it is sufficiently mixed granulation, and pelletizing press sheet is dried i.e.
Can.
The mass fraction relation adding each component in described preparation method is: the common extract of Chinese herbal medicine 16 parts, Fructus Rubi carry
Take thing 5 parts, sodium bicarbonate 20 parts, polyethylene glycol 6000 6 parts, citric acid 22 parts, diluent 15 parts, sweeting agent 0.4 part,
Binding agent 0.5 part.
Wherein, the preparation method of the common extract of said herbal medicine: in terms of butt, take Exocarpium Citrulli 26 parts, 22 parts of Folium Mori, mountain
Short, bristly hair or beard 25 parts, Radix Polygoni Multiflori 4 parts, Pericarpium Citri Reticulatae 12 parts and 28 parts of Poria, carry out pulverizing and sieving and uniformly mixing by above-mentioned each composition, mixed powder
End carries out microwave radiation processing 30-35min, and the power of microwave is 700W, and under Ultrasonic Conditions, adding solid-liquid ratio is 1:25's
Mass fraction be 18% ethanol carry out extracting 4h, obtain Chinese herbal medicine alcohol extract, then obtained with lyophilizing by outstanding steaming of vacuum
To the common water extract of Chinese herbal medicine.
The preparation method of above-mentioned raspberry extract is: take fresh Fructus Rubi adding the concentration that solid-liquid ratio is 1:1 is 4% ethanol
Pulling an oar, extract at the ethanol that addition concentration is 20% after homogenate, solid-liquid ratio is 1:12, and microwave radiation 2h adds
Volume is 95% ethanol of extracting liquid volume 5%, extracts 2-4h after being sufficiently stirred under Ultrasonic Conditions, centrifugal, takes supernatant, dense
Contracting, lyophilizing and get final product.
Below by zoopery, embodiment 1-3 and comparative example 1-2 are carried out experiment effect checking.
1, laboratory animal
C57/BL6 mice, male, body weight 20-30g, purchased from Beijing Vital River Experimental Animals Technology Co., Ltd., licence
Number: SCXK (capital) 2014-0006.
2 test methods
C57/BL6 mice is randomly divided into 7 groups by body weight: embodiment 1 group, embodiment 2 groups, embodiment 3 groups, comparative example 1 group, right
Ratio 2 groups, normal group and model group, often group 10.Embodiment 1 group, embodiment 2 groups, embodiment 3 groups and comparative example 1-2 group,
Model group is high fat diet group, and in high fat diet group diet, the addition of fat is 2 times of normal group.Embodiment 1-3 group, right
Ratio 1-2 group is all added in diet according to the product content of 700mg/kg, and model group and normal group all add the agar of equivalent.
Experiment periods is January.Ad lib and water inlet, the doomsday, overnight stopping eating was not cut off the water, after docking in morning next day, eye socket take blood, cervical dislocation
Lethal, and take required organ and carry out indices mensuration.
3, result of the test
Measure Mouse Weight, and by test kit to T-CHOL in mice serum (TC), triglyceride (TG) and high density
The concentration of lipoprotein cholesterol (HDL-C) is measured, and the results are shown in Table 1.It can be seen that embodiment 1 group to 3 groups and normal control
All there is no significant difference at blood lipid level between group, and comparative example 1-2 group improves the level of blood fat significantly lower than embodiment 1-3
Group；In terms of reducing increased weight, although each experimental group is all clearly distinguishable from normal group, but, the increment of comparative example 1-2 group shows
Write higher than embodiment 1-3 group.Thus illustrate the present invention is added with the enforcement of laminarin, citrus pectin and raspberry extract
Example 1-3 group can effectively suppress body weight to increase, and significantly improves blood lipid level.It addition, can be seen by comparative example 1 and 2 contrast
Go out, add laminarin, citrus pectin and raspberry extract all can play the effect of loss of weight blood fat reducing, but laminarin, lemon
The effect of mango glue is better than raspberry extract, but analyzes from addition, and raspberry extract is used alone effect should be able to
Being better than that Thallus Laminariae (Thallus Eckloniae) is many and being used alone of citrus pectin, raspberry extract has effect of highly significant in terms of health slimming, also says
Understand that the present invention has good application effect in terms of health slimming.
The measurement result of table 1 each experimental mice fat-reducing related data
| Group | TC (mMol/L) | TG(mMol/L) | HDL(mMol/L) | Increased weight (/g) |
| Embodiment 1 group | 4.536±0.243 | 0.969±0.036 | 2.698±0.138 | 6.46±0.82* |
| Embodiment 2 groups | 4.582±0.224 | 0.934±0.059 | 2.745±0.257 | 6.45±0.79* |
| Embodiment 3 groups | 4.545±0.238 | 1.017±0.024 | 2.778±0.122 | 6.59±0.71* |
| Comparative example 1 group | 4.824±0.243* | 1.014±0.086 | 2.754±0.262 | 8.77±0.72** |
| Comparative example 2 groups | 5.162±0.996** | 1.172±0.089 | 2.921±0.126 | 9.01±0.96** |
| Model group | 5.475±0.896** | 1.297±0.262* | 3.368±0.321* | 12.58±0.78** |
| Normal group | 3.985±0.071 | 0.975±0.101 | 2.682±0.121 | 4.98±0.72 |
Note: * * P < 0.01；*P<0.05.
Claims (10)
1. an effervescent tablet for slimming herbal tea, it is characterised in that according to mass parts, in terms of butt, including following components: Chinese herbal medicine is common
With extract 10-16 part, laminarin 6-10 part and citrus pectin 4-8 part, raspberry extract 4-6 part；Wherein, in described
The common extract of medical herbs is by Exocarpium Citrulli 20-30 part, Folium Mori 10-25 part, Fructus Crataegi 18-26 part, Radix Polygoni Multiflori 4-6 part, Pericarpium Citri Reticulatae 8-15 part
Jointly extract with Poria 16-30 part and obtain.
2. effervescent tablet for slimming herbal tea as claimed in claim 1, it is characterised in that the preparation method of described laminarin is: sea
Band is dried powder process, adds water and is stirred continuously, will wherein add cellulase and protease afterwards, and heating in water bath is carried out after being stirred continuously
Ultrasonic Treatment；The enzymolysis solution obtained is centrifuged, concentrates and lyophilizing, standby.
3. effervescent tablet for slimming herbal tea as claimed in claim 2, it is characterised in that the concrete preparation method of above-mentioned laminarin
For: taking Thallus Laminariae (Thallus Eckloniae) and be dried, grinding flour sieves, and adding water and making its solid-liquid ratio is 1:25-35, and is stirred continuously, and will wherein add afterwards
Mass fraction is the cellulase that mass ratio is 2-3:1 of 0.2-0.5%: protease, in 55-65 DEG C of heating in water bath and constantly stirs
After mixing 30-40min, then carry out ultrasonic Treatment；Finally the enzymolysis solution obtained is centrifuged, concentrates and lyophilizing, standby.
4. effervescent tablet for slimming herbal tea as claimed in claim 1, it is characterised in that the preparation method of above-mentioned citrus pectin is: will
Fresh Fericarpium Citri Limoniae adds water, and regulates pH, extracts, then add alcohol precipitation, finally will obtain under water-bath and Ultrasonic Conditions
Precipitated liquid be centrifuged, concentrate and lyophilizing, standby.
5. effervescent tablet for slimming herbal tea as claimed in claim 1, it is characterised in that the extraction of the common extract of described Chinese herbal medicine
Method is: in terms of butt, takes Exocarpium Citrulli 20-30 part, Folium Mori 10-25 part, Fructus Crataegi 18-26 part, Radix Polygoni Multiflori 4-6 part, Pericarpium Citri Reticulatae 8-15
Part and Poria 16-30 part, pulverize and sieve above-mentioned each composition, and uniformly mix, first entered by above-mentioned mixed powder
Row microwave treatment, then under Ultrasonic Conditions, adds the ethanol that mass fraction is 15-20% that solid-liquid ratio is 1:22-26 and enters
Row extracts 2-4h, obtains Chinese herbal medicine alcohol extract, then obtains the common water extract of Chinese herbal medicine by outstanding steaming of vacuum with lyophilizing.
6. effervescent tablet for slimming herbal tea as claimed in claim 5, it is characterised in that above-mentioned mixed-powder carries out microwave radiation processing
30-35min, the power of microwave is 700W.
7. effervescent tablet for slimming herbal tea as claimed in claim 1, it is characterised in that the preparation method of described raspberry extract is:
Take fresh Fructus Rubi add solid-liquid ratio be the concentration of 1:1 be that 2-6% ethanol is pulled an oar, be 10-30% adding concentration after homogenate
Ethanol extract, solid-liquid ratio is 1:10-15, microwave radiation 1-2h, adds 95% second that volume is extracting liquid volume 5%
Alcohol, extracts 2-4h under Ultrasonic Conditions after being sufficiently stirred for, centrifugal, takes supernatant, concentrates, lyophilizing and get final product.
8. the preparation method of a kind of effervescent tablet for slimming herbal tea described in claim 1-7 any claim, it is characterised in that
(1) weighing polyethylene glycol 6000, add sodium bicarbonate, stir after melting, cooling is ground, and sieving for standby is carbon
Acid hydrogen sodium wrappage granule；
(2) taking the above-mentioned common extract of prepared Chinese herbal medicine, starfish saponin and Stichopus japonicus polysaccharide, addition citric acid, diluent are abundant
Mix homogeneously also sieves；
(3) product after processing that step (1) and step (2) sieved mixes in proportion, and adds binding agent and be sufficiently mixed
Pelletizing, pelletizing press sheet is dried.
9. the preparation method of effervescent tablet for slimming herbal tea as claimed in claim 8, it is characterised in that dilute in described step (2)
Releasing agent is lactose or alginate jelly.
10. the preparation method of effervescent tablet for slimming herbal tea as claimed in claim 8, it is characterised in that add in described preparation method
The mass fraction relation entering each component is: Chinese herbal medicine common extract 10-16 part, laminarin 6-10 part and citrus pectin 4-
8 parts, raspberry extract 4-6 part, sodium bicarbonate 10-25 part, polyethylene glycol 6000 2-6 part, citric acid 12-24 part, diluent
8-15 part, sweeting agent 0.2-0.4 part, binding agent 0.2-0.6 part.
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| CN114209055A (en) * | 2021-12-20 | 2022-03-22 | 星工坊(苏州)生物科技有限公司 | Composition helpful for blocking oil absorption, preparation method and preparation |
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Application publication date: 20161116 |