CN106075386A - A kind of anti-tired anti-ageing iron supplement capsules and preparation method thereof - Google Patents
A kind of anti-tired anti-ageing iron supplement capsules and preparation method thereof Download PDFInfo
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- CN106075386A CN106075386A CN201610713545.6A CN201610713545A CN106075386A CN 106075386 A CN106075386 A CN 106075386A CN 201610713545 A CN201610713545 A CN 201610713545A CN 106075386 A CN106075386 A CN 106075386A
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- iron
- ageing
- testa
- tired
- iron supplement
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- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 title claims abstract description 58
- 229910052742 iron Inorganic materials 0.000 title claims abstract description 27
- 239000013589 supplement Substances 0.000 title claims abstract description 15
- 239000002775 capsule Substances 0.000 title claims abstract description 14
- 230000003712 anti-aging effect Effects 0.000 title claims abstract description 12
- 238000002360 preparation method Methods 0.000 title claims abstract description 10
- 150000003839 salts Chemical class 0.000 claims abstract description 10
- 241000282894 Sus scrofa domesticus Species 0.000 claims abstract description 9
- 229960002089 ferrous chloride Drugs 0.000 claims abstract description 9
- NMCUIPGRVMDVDB-UHFFFAOYSA-L iron dichloride Chemical compound Cl[Fe]Cl NMCUIPGRVMDVDB-UHFFFAOYSA-L 0.000 claims abstract description 9
- 241001116389 Aloe Species 0.000 claims abstract description 7
- 108091005658 Basic proteases Proteins 0.000 claims abstract description 7
- 235000011399 aloe vera Nutrition 0.000 claims abstract description 7
- 235000015278 beef Nutrition 0.000 claims abstract description 7
- 229920001184 polypeptide Polymers 0.000 claims abstract description 7
- 102000004196 processed proteins & peptides Human genes 0.000 claims abstract description 7
- 108090000765 processed proteins & peptides Proteins 0.000 claims abstract description 7
- 235000010837 Echinocereus enneacanthus subsp brevispinus Nutrition 0.000 claims abstract description 6
- 235000006850 Echinocereus enneacanthus var dubius Nutrition 0.000 claims abstract description 6
- 239000002994 raw material Substances 0.000 claims abstract description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 16
- 239000000843 powder Substances 0.000 claims description 13
- 239000000463 material Substances 0.000 claims description 12
- 239000006228 supernatant Substances 0.000 claims description 10
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 9
- 239000003814 drug Substances 0.000 claims description 7
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 6
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 6
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 6
- 102000001554 Hemoglobins Human genes 0.000 claims description 6
- 108010054147 Hemoglobins Proteins 0.000 claims description 6
- 244000018795 Prunus mume Species 0.000 claims description 6
- 235000011158 Prunus mume Nutrition 0.000 claims description 6
- 238000006243 chemical reaction Methods 0.000 claims description 6
- 238000001914 filtration Methods 0.000 claims description 6
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims description 6
- 238000010298 pulverizing process Methods 0.000 claims description 6
- 238000003756 stirring Methods 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 244000157072 Hylocereus undatus Species 0.000 claims description 5
- 239000013522 chelant Substances 0.000 claims description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 3
- 235000008331 Pinus X rigitaeda Nutrition 0.000 claims description 3
- 235000011613 Pinus brutia Nutrition 0.000 claims description 3
- 241000018646 Pinus brutia Species 0.000 claims description 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 3
- 235000010323 ascorbic acid Nutrition 0.000 claims description 3
- 229960005070 ascorbic acid Drugs 0.000 claims description 3
- 239000011668 ascorbic acid Substances 0.000 claims description 3
- 229960000935 dehydrated alcohol Drugs 0.000 claims description 3
- 239000012153 distilled water Substances 0.000 claims description 3
- 238000001035 drying Methods 0.000 claims description 3
- 238000010438 heat treatment Methods 0.000 claims description 3
- 238000009413 insulation Methods 0.000 claims description 3
- 235000013372 meat Nutrition 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 3
- 229910052757 nitrogen Inorganic materials 0.000 claims description 3
- 239000002244 precipitate Substances 0.000 claims description 3
- 239000001509 sodium citrate Substances 0.000 claims description 3
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims description 3
- 230000007480 spreading Effects 0.000 claims description 3
- 238000001291 vacuum drying Methods 0.000 claims description 3
- 244000047855 Acalypha wilkesiana Species 0.000 claims description 2
- 235000018481 Hylocereus undatus Nutrition 0.000 claims description 2
- 239000007788 liquid Substances 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 6
- 208000007502 anemia Diseases 0.000 abstract description 4
- 235000013924 ferrous gluconate Nutrition 0.000 abstract description 3
- 239000004222 ferrous gluconate Substances 0.000 abstract description 3
- 229960001645 ferrous gluconate Drugs 0.000 abstract description 3
- 230000036541 health Effects 0.000 abstract description 3
- VRIVJOXICYMTAG-IYEMJOQQSA-L iron(ii) gluconate Chemical compound [Fe+2].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O VRIVJOXICYMTAG-IYEMJOQQSA-L 0.000 abstract description 3
- 238000010521 absorption reaction Methods 0.000 abstract description 2
- 230000009471 action Effects 0.000 abstract description 2
- 235000001014 amino acid Nutrition 0.000 abstract description 2
- 150000001413 amino acids Chemical class 0.000 abstract description 2
- 230000002950 deficient Effects 0.000 abstract description 2
- 235000016709 nutrition Nutrition 0.000 abstract description 2
- 230000035764 nutrition Effects 0.000 abstract description 2
- 239000002699 waste material Substances 0.000 abstract description 2
- 240000008086 Echinocereus enneacanthus Species 0.000 abstract 1
- 229940024606 amino acid Drugs 0.000 abstract 1
- 239000008280 blood Substances 0.000 description 6
- 210000004369 blood Anatomy 0.000 description 6
- 229960000583 acetic acid Drugs 0.000 description 4
- 241001465754 Metazoa Species 0.000 description 2
- 206010010774 Constipation Diseases 0.000 description 1
- DKKCQDROTDCQOR-UHFFFAOYSA-L Ferrous lactate Chemical compound [Fe+2].CC(O)C([O-])=O.CC(O)C([O-])=O DKKCQDROTDCQOR-UHFFFAOYSA-L 0.000 description 1
- 206010070840 Gastrointestinal tract irritation Diseases 0.000 description 1
- 208000015710 Iron-Deficiency Anemia Diseases 0.000 description 1
- 244000046052 Phaseolus vulgaris Species 0.000 description 1
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 235000015249 blood sausages Nutrition 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 235000013925 ferrous lactate Nutrition 0.000 description 1
- 239000004225 ferrous lactate Substances 0.000 description 1
- 229940037907 ferrous lactate Drugs 0.000 description 1
- 229960001781 ferrous sulfate Drugs 0.000 description 1
- 239000011790 ferrous sulphate Substances 0.000 description 1
- 235000003891 ferrous sulphate Nutrition 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 210000004347 intestinal mucosa Anatomy 0.000 description 1
- BAUYGSIQEAFULO-UHFFFAOYSA-L iron(2+) sulfate (anhydrous) Chemical compound [Fe+2].[O-]S([O-])(=O)=O BAUYGSIQEAFULO-UHFFFAOYSA-L 0.000 description 1
- 229910000359 iron(II) sulfate Inorganic materials 0.000 description 1
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 239000012567 medical material Substances 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000003307 slaughter Methods 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
- A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
- A61K38/017—Hydrolysed proteins; Derivatives thereof from animals from blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
- A61K36/066—Clavicipitaceae
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/33—Cactaceae (Cactus family), e.g. pricklypear or Cereus
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K9/00—Medicinal preparations characterised by special physical form
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Abstract
The invention discloses a kind of anti-tired anti-ageing iron supplement capsules, be prepared by the raw materials in: aloe skin 20 30, Testa sojae atricolor 35 38, Fericarpium Citri Limoniae 22 28, crude salt 67, Testa arachidis hypogaeae 56, green prune 8 11, beef 30 33, fresh Sanguis sus domestica 220 300,2709 alkaline protease 57, ferrous chloride 25 30, Herba Ecliptae 1.8 3, Periostracum cicadae 1.7 2.2, Pitaya Flower 1.7 2.Health preparation anti-anemia action effect of the present invention is significantly better than Ferrous gluconate and ferrous chloride, and aminoacid and micromolecule polypeptide more can promote the absorption of ferrum, thus improve iron supplement effect, so being comparatively ideal iron-supplementing preparation, it is adaptable to improve iron-deficient nutrition anemia；The present invention is effectively utilized waste resource, indirect protection environment, improves resource utilization.
Description
Technical field
The present invention relates to health medicine technical field, particularly relate to a kind of anti-tired anti-ageing iron supplement capsules and preparation method thereof.
Background technology
At present, the preventing and treating of iron deficiency anemia mainly realizes by taking iron supplementary.Existing iron supplementary have ferrous sulfate,
Ferrous chloride, Ferrous gluconate, ferrous lactate etc., although these iron supplementary iron contents are high, but due to them in vivo
Utilization rate is relatively low, and there is metal rust taste in various degree and GI irritation, and research shows, polypeptide chelate iron is a kind of
Novel biology iron, can directly be absorbed by intestinal mucosa cells, and not producing digestive tract stimulates, and bioavailability is high, is preferable
Iron supplementary.
The blood flowed out after slaughtering animal is mainly used in making dish, blood powder, blood sausage and blood beans by China's many slaughterhouses
Oil etc., added value of product is low, also has quite a few blood to be directly discharged into environment, has both wasted the protein resource of preciousness, again
Severe contamination environment around, therefore, utilizes animal blood to prepare polypeptide ferrum to improving the added value of Sanguis sus domestica, profit to Sanguis sus domestica
Have great significance with preserving the ecological environment with going on industrialized developing road.
Summary of the invention
The object of the invention is contemplated to make up the defect of prior art, it is provided that a kind of anti-tired anti-ageing iron supplement capsules and preparation thereof
Method.
The present invention is achieved by the following technical solutions:
A kind of anti-tired anti-ageing iron supplement capsules, is prepared by the raw materials in:
Aloe skin 20-30, Testa sojae atricolor 35-38, Fericarpium Citri Limoniae 22-28, crude salt 6-7, Testa arachidis hypogaeae 5-6, green prune 8-11, beef 30-
33, fresh Sanguis sus domestica 220-300,2709 alkaline protease 5-7, ferrous chloride 25-30, Herba Ecliptae 1.8-3, Periostracum cicadae 1.7-2.2, fire
Dragon fruit flower 1.7-2.
The preparation method of described a kind of anti-tired anti-ageing iron supplement capsules, comprises the following steps:
(1) by after Herba Ecliptae, Periostracum cicadae, the Pitaya Flower flooding by 6-9 times amount, filter obtains Chinese medicine juice；
(2) aloe skin, Testa sojae atricolor, Fericarpium Citri Limoniae stir-fry 15-18 minute in being placed in pot, then pour crude salt into and enter pot and stir-fry whole to material
It is dried, then screens out unnecessary salt grain, finally leftover materials are pulverized into jointly with Testa arachidis hypogaeae powder；
(3) take green prune and dry pulverizing, obtain Armeniaca mume Sieb. dry powder；Beef is cut into slices, after uniformly spreading Armeniaca mume Sieb. dry powder, uniformly hammers into shape with hammer
Pine, then the sliced meat Chinese medicine juice handled well is fumigated 15-18 minute, obtain material in pot, dry in the air cool post-drying pulverizing；
(4) taking fresh Sanguis sus domestica, add the sodium citrate of its weight 0.4-0.5%, 2500-3000r/min is centrifuged 14-15min, abandons
Clear liquid, precipitate normal saline cleans, and is subsequently adding the distilled water of 3-4 times of volume, stirs, 50-60 under the conditions of lucifuge
DEG C heating 25-30min, obtain hemoglobin solutions；
(5) above-mentioned hemoglobin solutions is joined in 100-120 times of water, be placed in 40-50 DEG C of water-bath, add mixed liquor weight
2709 alkaline proteases of 2-3%, are 10-11 with sodium hydroxide regulation PH, and insulation reaction 6-7 hour adds acetic acid and adjusts pH value extremely
4-4.5, is incubated 18-20min at 90-95 DEG C, is cooled to room temperature, and 3500-4000r/min is centrifuged 2-3min, takes supernatant, adds
Enter the activated carbon of supernatant weight 1.5-2%, decolour two hours at 45-50 DEG C, sucking filtration, obtain destaining solution；
(6) take above-mentioned destaining solution, add the ascorbic acid of its liquor capacity 1-2%, be subsequently adding ferrous chloride, regulate with acetic acid
PH is 5-5.5, is passed through nitrogen, at room temperature hybrid reaction 8-10min, centrifugal 18-20min under 3500-4000r/min,
The supernatant obtained adds the dehydrated alcohol of its volume 3-5 times, stirring mixing 3-4 hour, sucking filtration, vacuum drying, obtains polypeptide
Chelate iron；
(7) by regrinding after above-mentioned steps gained material mix homogeneously, obtain fine powder, and load capsule, every heavy 1-1.2 gram,
Obtain.
The invention have the advantage that health preparation anti-anemia action effect of the present invention is significantly better than Ferrous gluconate and protochloride
Ferrum, aminoacid and micromolecule polypeptide more can promote the absorption of ferrum, thus improve iron supplement effect, so being comparatively ideal iron supplement system
Agent, it is adaptable to improve iron-deficient nutrition anemia；The present invention is effectively utilized waste resource, indirect protection environment, improves money
Source utilization rate；
Iron supplement of the present invention is effective, is suitable for crowd extensive, and health-care effect ideal has been also added with Herba Ecliptae, Periostracum cicadae, Pitaya Flower etc.
Food medical material, richness has given nourishing the liver and kidney of the present invention, anti-tired anti-ageing, lung moistening improving eyesight, loosening bowel to relieve constipation, the health-care effect of toxin expelling sleeping.
Detailed description of the invention
A kind of anti-tired anti-ageing iron supplement capsules, is prepared by the raw materials in:
Aloe skin 20, Testa sojae atricolor 35, Fericarpium Citri Limoniae 22, crude salt 6, Testa arachidis hypogaeae 5, green prune 8, beef 30, fresh Sanguis sus domestica 220,2709
Alkaline protease 5, ferrous chloride 25, Herba Ecliptae 1.8, Periostracum cicadae 1.7, Pitaya Flower 1.7.
The preparation method of described a kind of anti-tired anti-ageing iron supplement capsules, comprises the following steps:
(1) by after Herba Ecliptae, Periostracum cicadae, the Pitaya Flower flooding by 6 times amount, filter obtains Chinese medicine juice；
(2) aloe skin, Testa sojae atricolor, Fericarpium Citri Limoniae stir-fry in being placed in pot 15 minutes, then pour crude salt into and enter pot and stir-fry to material and all do
Dry, then screen out unnecessary salt grain, finally leftover materials are pulverized into jointly with Testa arachidis hypogaeae powder；
(3) take green prune and dry pulverizing, obtain Armeniaca mume Sieb. dry powder；Beef is cut into slices, after uniformly spreading Armeniaca mume Sieb. dry powder, uniformly hammers into shape with hammer
Pine, then the sliced meat Chinese medicine juice handled well is fumigated 15 minutes, obtain material in pot, dry in the air cool post-drying pulverizing；
(4) taking fresh Sanguis sus domestica, add the sodium citrate of its weight 0.4%, 2500r/min is centrifuged 14min, abandons supernatant, and precipitate is used
Normal saline cleans, and is subsequently adding the distilled water of 3 times of volumes, stirs, and under the conditions of lucifuge, 50 DEG C of heating 25min, obtain blood
Hemoglobin solution；
(5) above-mentioned hemoglobin solutions is joined in 100 times of water, be placed in 40 DEG C of water-baths, add mixed liquor weight 2%
2709 alkaline proteases, are 10 with sodium hydroxide regulation PH, insulation reaction 6 hours, and addition acetic acid tune pH value is to 4,90 DEG C of guarantors
Temperature 18min, is cooled to room temperature, and 3500r/min is centrifuged 2min, takes supernatant, adds the activated carbon of supernatant weight 1.5%,
Decolour two hours at 45 DEG C, sucking filtration, obtain destaining solution；
(6) take above-mentioned destaining solution, add the ascorbic acid of its liquor capacity 1%, be subsequently adding ferrous chloride, use vinegar acid for adjusting pH
Being 5, be passed through nitrogen, at room temperature hybrid reaction 8min, under 3500r/min, centrifugal 18min, adds in the supernatant obtained
The dehydrated alcohol of its volume 3 times, stirring mixing 3 hours, sucking filtration, vacuum drying, obtain polypeptide chelate iron；
(7) by regrinding after above-mentioned steps gained material mix homogeneously, obtain fine powder, and load capsule, every weight 1 gram, to obtain final product.
Claims (2)
1. an anti-tired anti-ageing iron supplement capsules, it is characterised in that be prepared by the raw materials in:
Aloe skin 20-30, Testa sojae atricolor 35-38, Fericarpium Citri Limoniae 22-28, crude salt 6-7, Testa arachidis hypogaeae 5-6, green prune 8-11, beef 30-
33, fresh Sanguis sus domestica 220-300,2709 alkaline protease 5-7, ferrous chloride 25-30, Herba Ecliptae 1.8-3, Periostracum cicadae 1.7-2.2, fire
Dragon fruit flower 1.7-2.
The preparation method of a kind of anti-tired anti-ageing iron supplement capsules the most as claimed in claim 1, it is characterised in that comprise the following steps:
(1) by after Herba Ecliptae, Periostracum cicadae, the Pitaya Flower flooding by 6-9 times amount, filter obtains Chinese medicine juice；
(2) aloe skin, Testa sojae atricolor, Fericarpium Citri Limoniae stir-fry 15-18 minute in being placed in pot, then pour crude salt into and enter pot and stir-fry whole to material
It is dried, then screens out unnecessary salt grain, finally leftover materials are pulverized into jointly with Testa arachidis hypogaeae powder；
(3) take green prune and dry pulverizing, obtain Armeniaca mume Sieb. dry powder；Beef is cut into slices, after uniformly spreading Armeniaca mume Sieb. dry powder, uniformly hammers into shape with hammer
Pine, then the sliced meat Chinese medicine juice handled well is fumigated 15-18 minute, obtain material in pot, dry in the air cool post-drying pulverizing；
(4) taking fresh Sanguis sus domestica, add the sodium citrate of its weight 0.4-0.5%, 2500-3000r/min is centrifuged 14-15min, abandons
Clear liquid, precipitate normal saline cleans, and is subsequently adding the distilled water of 3-4 times of volume, stirs, 50-60 under the conditions of lucifuge
DEG C heating 25-30min, obtain hemoglobin solutions；
(5) above-mentioned hemoglobin solutions is joined in 100-120 times of water, be placed in 40-50 DEG C of water-bath, add mixed liquor weight
2709 alkaline proteases of 2-3%, are 10-11 with sodium hydroxide regulation PH, and insulation reaction 6-7 hour adds acetic acid and adjusts pH value extremely
4-4.5, is incubated 18-20min at 90-95 DEG C, is cooled to room temperature, and 3500-4000r/min is centrifuged 2-3min, takes supernatant, adds
Enter the activated carbon of supernatant weight 1.5-2%, decolour two hours at 45-50 DEG C, sucking filtration, obtain destaining solution；
(6) take above-mentioned destaining solution, add the ascorbic acid of its liquor capacity 1-2%, be subsequently adding ferrous chloride, regulate with acetic acid
PH is 5-5.5, is passed through nitrogen, at room temperature hybrid reaction 8-10min, centrifugal 18-20min under 3500-4000r/min,
The supernatant obtained adds the dehydrated alcohol of its volume 3-5 times, stirring mixing 3-4 hour, sucking filtration, vacuum drying, obtains polypeptide
Chelate iron；
(7) by regrinding after above-mentioned steps gained material mix homogeneously, obtain fine powder, and load capsule, every heavy 1-1.2 gram,
Obtain.
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