CN106075014A - One treats colpitic Chinese medicine preparation and preparation method - Google Patents

One treats colpitic Chinese medicine preparation and preparation method Download PDF

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CN106075014A
CN106075014A CN201610624566.0A CN201610624566A CN106075014A CN 106075014 A CN106075014 A CN 106075014A CN 201610624566 A CN201610624566 A CN 201610624566A CN 106075014 A CN106075014 A CN 106075014A
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radix
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herba
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牛艳红
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牛艳红
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/09—Lichens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/234—Cnidium (snowparsley)
    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/59—Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A61K36/746—Morinda
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/894—Dioscoreaceae (Yam family)
    • A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • A—HUMAN NECESSITIES
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Abstract

The invention discloses one and treat colpitic Chinese medicine preparation and preparation method, belong to the field of Chinese medicines；The raw material of Chinese medicine preparation effective ingredient of the present invention consists of: Radix Morindae Officinalis, Rhizoma Dioscoreae, the Radix Pulsatillae, Pericarpium Pyri, Radix Osbeckiae Crinitae, Caulis seu radix berberidis virgetori, Flos Lonicerae, Fructus Ponciri Trifoliatae (Fructus Ponciri Trifoliatae Immaturus), Caulis Arcangelisiae, Herba Iresines Herbstii, Radix Rubiae, Radix Stephaniae hemandifoliae, Herba Allii bulleyani, Fructus Cnidii, Usnea and Herba Osbeckiae；Selected by Chinese medicine preparation of the present invention, medical material compatibility is suitable, meeting Chinese medicine and pharmacy and modern medicine theory, and have effect of heat-clearing and toxic substances removing, dispelling wind for relieving itching, removing dampness and killing parasites, the vaginitis caused for treating various symptoms has unique curative effect, and it is evident in efficacy, quick result, non-relapse after healing, safe without toxic side effect, the purpose for the treatment of both the principal and secondary aspects of a disease can be reached, cost is relatively low, and patient adaptability is strong, wide popularization and application on clinic.

Description

One treats colpitic Chinese medicine preparation and preparation method
Art
The present invention relates to the field of Chinese medicines, particularly relate to one and treat colpitic Chinese medicine preparation and preparation method.
Background technology
Vaginitis i.e. colpitis, the intrusion of pathogen is had certainly by normal healthy women vagina due to the feature of anatomical tissue So defense function, such as the Guan Bi of vaginal orifice, vagina front and rear wall is close to, vaginal epithelial cell hypertrophy under the influence of estrogen and Cells of superficial layer keratinization, vagina acid-base degree keeps balance, makes the breeding of pathogen of adaptation alkalescence be suppressed, and neck tube mucus in Alkalescence, when the natural defense function of vagina is destroyed, pathogen is prone to invade, and causes colpitis.
Having aerobe and anaerobe to reside in intravaginal under normal circumstances, form normal vaginal microbial flora, any reason will Ecological balance between vagina and flora is broken, it is possible to formation condition pathogenic bacterium.The most common have bacterial vaginosis, beads Bacterium property vaginitis, trichomonal vaginitis, senile vaginitis, infantile vaginitis.Bacterial vaginosis: 10%～40% patient Without clinical symptoms, there is symptom mainly to show as vaginal secretions and increase, have a fish like smell, especially sexual intercourse postemphasis, can be with gently Degree pruritus vulvae or burning sensation.Checking and see that vaginal mucosa shows without congested inflammation, secretions feature is canescence, uniform one Causing, thin, length attaches to vaginal wall, is easily wiped away from vaginal wall by secretions；Monilial vaginitis: pruritus vulvae, causalgia, Sexual anhedonia, frequent micturition, dysurea.When dysurea feature is to urinate, urine stimulates the pudendum of edema and vestibule to cause pain, feature secretions: White stiff is curdled milk or bean dregs sample, vulvitis-ground pattern erythema, edema, scratch, and vaginitis-edema, erythema, white are membranaceous Thing.
At present, hospital is to treatment vaginitis many employings doctor trained in Western medicine antibiotic therapy, but effect is less desirable, takes stopgap measures and does not controls This, it is easy to recurrence, long-term taking can produce drug resistance, the most certain side effect, and the course for the treatment of is longer, costly, gives The spirit of patient and economy bring the biggest puzzlement.
Summary of the invention
The invention provides one and treat colpitic Chinese medicine preparation and preparation method；Medical material selected by Chinese medicine preparation of the present invention Compatibility is suitable, meets Chinese medicine and pharmacy and modern medicine theory, and has effect of heat-clearing and toxic substances removing, dispelling wind for relieving itching, removing dampness and killing parasites, The vaginitis caused for treating various symptoms has unique curative effect, and evident in efficacy, quick result, non-relapse after healing, peace Atoxic side effect, it is possible to reach the purpose for the treatment of both the principal and secondary aspects of a disease, cost is relatively low, and patient adaptability is strong, and clinic is widely popularized Application.
For achieving the above object, technical scheme is implemented as follows:
One treats colpitic Chinese medicine preparation, makes raw material composition and the parts by weight of described Chinese medicine preparation effective ingredient For:
Make described Chinese medicine preparation effective ingredient raw material composition and parts by weight be:
Make described Chinese medicine preparation effective ingredient raw material composition and parts by weight be:
Make described Chinese medicine preparation effective ingredient raw material composition and parts by weight be:
A kind of preparation method treating colpitic Chinese medicine preparation, comprises the following steps that:
(1) Radix Morindae Officinalis, the Radix Pulsatillae, Pericarpium Pyri, Radix Osbeckiae Crinitae, Caulis seu radix berberidis virgetori, Fructus Ponciri Trifoliatae (Fructus Ponciri Trifoliatae Immaturus), Caulis Arcangelisiae, Herba Allii bulleyani and Usnea are cleaned, put Enter in container, add the distilled water of 8～10 times amount, after soaking 5～6 hours, boil 3～4 hours, extract；Again add 6～8 Times amount distilled water, boils 2～3 hours, extracts；Finally, add 4～6 times amount distilled water, heated and boiled 1～2 hours, extract；Close And three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10～1.13, standby；
(2) Rhizoma Dioscoreae and Radix Stephaniae hemandifoliae are put into container, carry out pulverization process, grind into powder, obtain the fine powder of 180 mesh, standby；
(3) Flos Lonicerae, Radix Rubiae and Fructus Cnidii are cleaned, immerse 5 times amount 80% alcohol solution dipping 1～2 hours, add Heat is extracted 3 hours, reclaims ethanol, filters, obtains filtrate, and concentration is that at 65 DEG C, relative density is the thick paste of 1.12～1.16, standby；
(4) Herba Iresines Herbstii and Herba Osbeckiae are cleaned, chopping, put into container, twist juice, filter impurity, stay juice standby；
(5) thick paste, fine powder and the juice obtained by above-mentioned steps (1)～(4) is made capsule, obtain described treatment Colpitic Chinese medicine preparation.
The property of medicine of Chinese medicine used by the present invention is as follows:
Radix Morindae Officinalis: sweet in the mouth, pungent, slightly warm in nature；Return kidney, Liver Channel.Kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.For impotence and seminal emission, palace Cold infertile, menoxenia, few abdomen cold type of pain, rheumatic arthralgia, muscles and bones flaccidity is soft.
Rhizoma Dioscoreae: sweet in the mouth, property is put down；Return spleen, lung, kidney channel.Spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, Incessant chronic diarrhea, the deficiency of the lung breathes with cough, and emission due to deficiency of the kidney, leukorrhagia, frequent micturition, deficiency-heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) spleen reinforcing stomach invigorating.For insufficiency of the spleen lack of appetite, Have loose bowels loose stool, leukorrhagia." detailed outline " carries: " kidney tonifying gas, strengthening the spleen and stomach, stopping leak dysentery, reduce phlegm saliva, moistens fur.”
The Radix Pulsatillae: bitter in the mouth, cold in nature；Return stomach, large intestine channel.Heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery, removing dampness and killing parasites.Cure mainly dysentery, Epistaxis, metrorrhagia, internal hemorrhoid with bleeding, cold and heat pyrexial malaria, leukorrhagia, pudendal pruritus, eczema, scrofula, ulcerative carbuncle, eyes swelling pain." Japan hanako materia medica " carries: " control All pathogenic wind and warm waist knee joint, improving eyesight, disappear superfluous.Son: function is ibid.”
Pericarpium Pyri: sweet in the mouth, puckery, cool in nature, nontoxic；Return lung, the heart, kidney, large intestine channel.Clearing away heart-fire and moistening the lung, pathogenic fire reducing promotes the production of body fluid, and solves sore.Main Control summer-heat excessive thirst, xeropulmonary cough, spit blood, dysentery, scabies, carbuncle on the back, furuncle." book on Chinese herbal medicine is the newest " carries: " clearing heart fire, nourishing kidney tonifying YIN, Quenching the thirst in main Tianjin, relieving restlessness is dried.”
Radix Osbeckiae Crinitae: sweet in the mouth, puckery, property is put down.Clearing away heat-damp and promoting diuresis, cough-relieving, regulating menstruation.For acute gastroenteritis, bacillary dysentery, digestion Bad, chronic bronchitis, spit blood, menoxenia, qi-restoratives kidney tonifying, astringing to arrest bleeding.Controlling consumptive disease wound cough to spit blood, lower limb are aching and limp, muscle Bone contracture, urinary incontinence, nebulousurine leucorrhea.
Caulis seu radix berberidis virgetori: bitter in the mouth, cold in nature；Return liver, stomach, large intestine channel.Heat-clearing and toxic substances removing.Treating the liver is scorching, cholecystitis, enteritis, bacillary dysentery, throat Inflammation, conjunctivitis, urethritis, sore swollen toxin." Guangxi Chinese herbal medicine " carries: " heat-clearing and toxic substances removing.Control bacillary dysentery, gastroenteritis, throat Inflammation, stomatitis, urethritis, acute conjunctivitis, skin infection festers.Prevention epidemic encephalitis.”
Flos Lonicerae: sweet in the mouth, micro-hardship, cold in nature；Return lung, stomach, the heart, large intestine channel.Heat clearing away is eliminating evil, dispelling wind-heat, removing summer-heat blood poison.Existing Showing for pharmacological research, the effective ingredient in Flos Lonicerae has antibacterial and antivirus action, to staphylococcus aureus, hemolytic Streptococcus, dysentery bacterium, Bacillus typhi, meningococcus, Diplococcus pneumoniae, bacillus pyocyaneus and influenza virus etc. have bright Aobvious inhibitory action, and immunologic function can be strengthened, antiinflammatory, antipyretic, inflammation there is is obvious inhibiting effect.
Fructus Ponciri Trifoliatae (Fructus Ponciri Trifoliatae Immaturus): acrid in the mouth, hardship, warm in nature.Dispersing the stagnated liver-QI for regulating the stomach, regulating QI to relieve pain.Control distension and fullness of the chest and abdomen, stomachache, hernia, testis swelling, breast Room tuberculosis, uterine prolapse, traumatic injury；Alcoholic intoxication." Chinese herbal medicine is commonly used in Shanghai " carries: " promoting the circulation of QI, stomach invigorating, relieving constipation.Control stomach swollen Full, dyspepsia, constipation, uterine prolapse, tuberculosis of breast.”
Caulis Arcangelisiae: bitter in the mouth, cold in nature；GUIXIN, lung, large intestine channel.Clearing away heat-damp and promoting diuresis, pain relieving of detoxifying.For prevent influenza, Leptospirosis, controls acute gastroenteritis, bacillary dysentery, tonsillitis, bronchitis, malaria；Eye conjunctivitis, skin are controlled in external Skin eczema, impetigo, vaginitis.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " heat-clearing and toxic substances removing.Control enteritis, bacillary dysentery, tonsil Inflammation, bronchitis, furuncle and phyma, malaria, dermatitis, eczema, impetigo, tinea pedis infects.”
Herba Iresines Herbstii: sweet in the mouth, micro-hardship, cool in nature；Return liver, large intestine channel.Cooling blood for hemostasis, clearing away heat-damp and promoting diuresis, removing toxic substances.Main haematemesis, epistaxis, Hemoptysis, has blood in stool, metrorrhagia, and dysentery is had loose bowels, damp-heat vaginal discharge, carbuncle." mountain of papers Chinese herbal medicine " carries: " relaxing muscles and tendons to promote blood circulation, menstruction regulating and pain relieving.Control the moon Through uncomfortable, epistaxis, dysmenorrhea, fracture.”
Radix Rubiae: bitter in the mouth, cold in nature.Return Liver Channel.Removing heat from blood and promoting blood circulation, blood stasis dispelling, stimulates the menstrual flow.For spitting blood, epistaxis, metrostaxis, wound Hemorrhage, amenorrhea stasis blocking, arthralgia, tumbling and swelling.Cooling blood for hemostasis, blood circulation promoting and blood stasis dispelling: this product is stopped blooding and do not stayed the stasis of blood, goes out for heat syndrome Blood, amenorrhea stomachache, traumatic injury.Join Os Sepiae hemostasis power higher.
Radix Stephaniae hemandifoliae: bitter in the mouth, cold in nature；GUIXIN, liver, large intestine channel.Heat-clearing and toxic substances removing, eliminating stasis to stop pain.Main flu, pharyngalgia, diarrhoea, dysentery Disease, cellulitis toxic swelling, stomachache, wind syndrome of head pain, rheumatic arthralgia, traumatic injury.
Herba Allii bulleyani: acrid in the mouth, sweet, property is put down；Return liver, spleen channel.Promoting blood circulation to remove blood stasis, dispelling wind for relieving itching.Main traumatic injury, gunshot wound, Herba Urticae Cannabinae Rash, psoriasis, dermatitis rhus.
Fructus Cnidii: acrid in the mouth, hardship, warm in nature.Warming the kidney to invigorate YANG, dampness, wind dispelling insecticide.For sexual impotence, cold womb, cold-damp leukorrhagia, wet Numbness lumbago, external treatment vulval eczema, married woman's pudendal pruritus, trichomonal vaginitis.Modern pharmacological research confirms, ethanol extraction has anti-true Bacterium effect.
Usnea: bitter in the mouth, sweet, property is put down；GUIXIN, kidney, lung meridian.Liver heat removing is reduced phlegm, hemostasis removing toxic substances.Control headache, conjunctival congestion, expectorant of coughing Many, malaria, scrofula, leucorrhea, metrorrhagia, traumatic hemorrhage, carbuncle, venom." Chinese herbal medicine is commonly used in Tibet " carries: " heat-clearing and toxic substances removing, only Cough and reduce phlegm.Control trauma infection contamination, pyogenic infection, venom, pulmonary tuberculosis cough with copious phlegm, cervical adenitis, mastitis.”
Herba Osbeckiae: acrid in the mouth, light, property is put down；Return lung, spleen, liver, large intestine channel.Reduce phlegm dampness removing, hemostasis by removing blood stasis, removing toxic substances and promoting subsidence of swelling.Master coughs Cough, asthma, dysentery, have loose bowels, spit blood, spitting of blood, have blood in stool, amenorrhea, infantile malnutrition, rheumatic ostalgia, traumatic injury." Nanning City's medicine will " Carry: " eliminating blood stasis to promote regeneration of blood, pain relieving restrains.Control interior external haemorrhage, infantile malnutrition, ulcerative gingivitis, toothache, cough.”
The present invention compared with prior art, has the advantages that
Selected by Chinese medicine preparation of the present invention, medical material compatibility is suitable, meets Chinese medicine and pharmacy and modern medicine theory, and has clear Thermal detoxification, dispelling wind for relieving itching, effect of removing dampness and killing parasites, the vaginitis caused for treating various symptoms has unique curative effect, and treats Effect is notable, quick result, non-relapse after healing, safe without toxic side effect, it is possible to reach the purpose for the treatment of both the principal and secondary aspects of a disease, and cost is relatively low, Patient adaptability is strong, wide popularization and application on clinic.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
A kind of preparation method treating colpitic Chinese medicine preparation, comprises the following steps that:
(1) Radix Morindae Officinalis, the Radix Pulsatillae, Pericarpium Pyri, Radix Osbeckiae Crinitae, Caulis seu radix berberidis virgetori, Fructus Ponciri Trifoliatae (Fructus Ponciri Trifoliatae Immaturus), Caulis Arcangelisiae, Herba Allii bulleyani and Usnea are cleaned, put Enter in container, add the distilled water of 8～10 times amount, after soaking 5～6 hours, boil 3～4 hours, extract；Again add 6～8 Times amount distilled water, boils 2～3 hours, extracts；Finally, add 4～6 times amount distilled water, heated and boiled 1～2 hours, extract；Close And three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10～1.13, standby；
(2) Rhizoma Dioscoreae and Radix Stephaniae hemandifoliae are put into container, carry out pulverization process, grind into powder, obtain the fine powder of 180 mesh, standby；
(3) Flos Lonicerae, Radix Rubiae and Fructus Cnidii are cleaned, immerse 5 times amount 80% alcohol solution dipping 1～2 hours, add Heat is extracted 3 hours, reclaims ethanol, filters, obtains filtrate, and concentration is that at 65 DEG C, relative density is the thick paste of 1.12～1.16, standby；
(4) Herba Iresines Herbstii and Herba Osbeckiae are cleaned, chopping, put into container, twist juice, filter impurity, stay juice standby；
(5) thick paste, fine powder and the juice obtained by above-mentioned steps (1)～(4) is made capsule, obtain described treatment Colpitic Chinese medicine preparation.
Usage and dosage: oral, every day 2 times, the most each 1 time, each 1 (every 0.5g), warm water delivery service after meal； Within 5 days, being 1 course for the treatment of, can fully recover 2～3 courses for the treatment of, the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage are same as in Example 1.
Embodiment 3
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage are same as in Example 1.
Embodiment 4
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage are same as in Example 1.
Embodiment 5
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage are same as in Example 1.
Clinical data:
1, case selection:
As treating colpitic Chinese medicine preparation, selecting the vaginitis patient 230 example clinical observation made a definite diagnosis, patient divides at random Become treatment group and matched group two groups, treatment group women 115 example, age 18～45 years old, 31.5 years old mean age, average course of disease 1 year； Matched group women 115 example, age 19～44 years old, 31.5 years old mean age, average course of disease 1 year.
Treatment group and the course of disease of two groups of cases of matched group, degrees of symptoms are basically identical, without significant difference, have comparable Property.
2, medicament selection:
Treatment group takes Chinese medicine preparation of the present invention, oral, every day 2 times, the most each 1 time, each 1 (every 0.5g), warm water delivery service after meal；Within 5 days, being 1 course for the treatment of, can fully recover 2～3 courses for the treatment of, the person's of being in a bad way meal with wine of following the doctor's advice adds Amount.
Matched group takes Hydrochloric Itraconazole Capsule in Human Body, oral, every day 2 times, every day 200mg, the course for the treatment of is depending on the state of an illness.
3, efficacy determination:
(1) cure: pruritus vulvae, causalgia, the symptom such as frequent micturition, dysurea all disappears, and leucorrhea routine examination is without exception.
(2) effective: above-mentioned symptom substantially alleviates, leucorrhea routine examination cleannes are obviously improved.
(3) effective: above-mentioned symptom has alleviated, and leucorrhea routine examination cleannes make moderate progress.
(4) invalid: by treatment after above-mentioned symptom without alleviating or increasing the weight of, vagina cleanness degree without improve or still look into see infusorian, Candidiasis, antibacterial.
4, result:
Result above shows, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Lu, female, 19 years old, Yangquan Shanxi people.Patient's leucorrhoea grow in quantity, yellow green, there are foam, a frowziness, pruritus vulvae, Have a strong impact on work and life, be diagnosed as vaginitis through examination in hospital, used several method to treat, and had no improvement, later I Institute goes to a doctor, and through taking Chinese medicine preparation of the present invention treatment, after taking 1 course for the treatment of, symptom substantially alleviates, after continuing to take 2 curative effects, Transference cure, follows up a case by regular visits to so far without recurrence.
2, Jiang, female, 32 years old, people from Shiyan, Hubei.Patient's pruritus vulvae, causalgia, vaginal secretions increases, and gynecologial examination is sent out Existing posterior fornix of vagina has a large amount of stiff curdled milk sample leucorrhea, and vaginal secretions checks the mycelia of visible candidiasis, is diagnosed as and examines Vaginitis, doctor gives Chinese medicine preparation of the present invention treatment, and after taking 1 course for the treatment of, symptom has alleviated, and continues to take 2 courses for the treatment of After, transference cure, recovery from illness, follow up a case by regular visits to after 1 year without recurrence.
3, Cai, female, 24 years old, Fujian Longyan people.Urgent micturition, dysurea during patient's urine, frequent micturition, the self-induction lower part of the body very itches unbearably, Gynecologial examination leucorrhea is many, and pudendum has the punctation being dispersed in, and once takes various western medicine, and symptom has no that improvement, doctor are given again Giving Chinese medicine preparation of the present invention treatment, after taking 1 course for the treatment of, symptom substantially alleviates, after continuing to take 1 course for the treatment of, and transference cure, fully recover from an illness More, follow up a case by regular visits to after half a year without recurrence.
4, certain is gone into business, female, 30 years old, Tongling, Anhui Province people.Patient suffers from vaginitis more than 1 year, pruritus vulvae, and with frequent micturition, dysurea And sexual anhedonia, use several drugs treatment, have no improvement, recommend to take Chinese medicine preparation of the present invention treatment by doctor, take 1 After the course for the treatment of, symptom is clearly better, and after continuing to take 2 courses for the treatment of, symptom all disappears, recovery from illness, follows up a case by regular visits to without recurrence after 5 months.
5, fourth, female, 41 years old, Distributions in Liaocheng of Shandong Province people.The many pruritus vulvaes of patient leucorrhea more than 1 year, time light time weight, dizzy weak, Dim complexion, gynecologial examination: vaginal secretions increases, vaginal mucosa is congested, and posterior fornix of vagina has volume leucorrhea, in lark pus Sexual secretion, is diagnosed as vaginitis.Use Drug therapy, and had no and alleviate, take Chinese medicine preparation of the present invention treatment upon somebody's introduction, After taking 1 course for the treatment of, pruritis alleviates, and leucorrhea significantly reduces in gynecologial examination, and after taking 3 courses for the treatment of, pruritis disappears, and fullys recover from an illness More.
6, Wei, female, 22 years old, people from Cangzhou, Hebei.Patient tells leucorrhoea grow in quantity post-abortion, and leucorrhea is as bean dregs sample, and accompanies pudendum Causalgia acute pruritus, frequent micturition dysurea, gynecologial examination: posterior fornix of vagina has volume leucorrhea, and white stiff curdled milk sample, pudendum is visible Scratch, is diagnosed as vaginitis, and doctor gives Chinese medicine preparation of the present invention treatment, and after taking 1 course for the treatment of, symptom has been alleviated, and takes 3 After the individual course for the treatment of, symptom all disappears, recovery from illness, and after 1 year, check is without recurrence.

Claims (5)

1. treat colpitic Chinese medicine preparation for one kind, it is characterised in that: make the raw material composition of described Chinese medicine preparation effective ingredient And parts by weight are:
Radix Morindae Officinalis 49～73 portions of Rhizoma Dioscoreaes, 47～71 parts of Pericarpium Pyri of 48～72 portions of Radix Pulsatillaes 47～71 parts
Radix Osbeckiae Crinitae 46～70 parts of Caulis seu radix berberidis virgetoris 46～45～69 portions of Fructus Ponciri Trifoliatae (Fructus Ponciri Trifoliatae Immaturus)s of 70 portions of Flos Loniceraes 44～68 parts
Caulis Arcangelisiae 44～68 parts of Herba Iresines Herbstiis 43～42～66 parts of Radix Stephaniae hemandifoliae of 67 portions of Radix Rubiaes 42～66 parts
Herba Allii bulleyani 42～66 parts of Fructus Cnidiis 41～38～62 parts of Herba Osbeckiaes of 64 portions of Usneas 38～62 parts.
One the most according to claim 1 treats colpitic Chinese medicine preparation, it is characterised in that: make described Chinese medicine preparation The raw material of effective ingredient forms and parts by weight are:
Radix Morindae Officinalis 53～69 portions of Rhizoma Dioscoreaes, 51～67 parts of Pericarpium Pyri of 52～68 portions of Radix Pulsatillaes 51～67 parts
Radix Osbeckiae Crinitae 50～66 parts of Caulis seu radix berberidis virgetoris 50～49～65 portions of Fructus Ponciri Trifoliatae (Fructus Ponciri Trifoliatae Immaturus)s of 66 portions of Flos Loniceraes 48～64 parts
Caulis Arcangelisiae 48～64 parts of Herba Iresines Herbstiis 47～46～62 parts of Radix Stephaniae hemandifoliae of 63 portions of Radix Rubiaes 46～62 parts
Herba Allii bulleyani 46～62 parts of Fructus Cnidiis 44～42～58 parts of Herba Osbeckiaes of 60 portions of Usneas 42～58 parts.
One the most according to claim 1 treats colpitic Chinese medicine preparation, it is characterised in that: make described Chinese medicine preparation The raw material of effective ingredient forms and parts by weight are:
Radix Morindae Officinalis 57～65 portions of Rhizoma Dioscoreaes, 55～63 parts of Pericarpium Pyri of 56～64 portions of Radix Pulsatillaes 55～63 parts
Radix Osbeckiae Crinitae 54～62 parts of Caulis seu radix berberidis virgetoris 54～53～61 portions of Fructus Ponciri Trifoliatae (Fructus Ponciri Trifoliatae Immaturus)s of 62 portions of Flos Loniceraes 52～60 parts
Caulis Arcangelisiae 52～60 parts of Herba Iresines Herbstiis 51～50～58 parts of Radix Stephaniae hemandifoliae of 59 portions of Radix Rubiaes 50～58 parts
Herba Allii bulleyani 50～58 parts of Fructus Cnidiis 48～46～54 parts of Herba Osbeckiaes of 56 portions of Usneas 46～54 parts.
One the most according to claim 1 treats colpitic Chinese medicine preparation, it is characterised in that: make described Chinese medicine preparation The raw material of effective ingredient forms and parts by weight are:
61 portions of Rhizoma Dioscoreaes of Radix Morindae Officinalis, 59 parts of Pericarpium Pyri of 60 portions of Radix Pulsatillaes 59 parts
58 parts of Caulis seu radix berberidis virgetoris of Radix Osbeckiae Crinitae, 57 portions of Fructus Ponciri Trifoliatae (Fructus Ponciri Trifoliatae Immaturus)s of 58 portions of Flos Loniceraes 56 parts
56 parts of Herba Iresines Herbstiis of Caulis Arcangelisiae, 54 parts of Radix Stephaniae hemandifoliae of 55 portions of Radix Rubiaes 54 parts
54 parts of Fructus Cnidiis of Herba Allii bulleyani, 50 parts of Herba Osbeckiaes of 52 portions of Usneas 50 parts.
5. the preparation method treating colpitic Chinese medicine preparation as described in any one of Claims 1 to 4, it is characterised in that: Comprise the following steps that:
(1) Radix Morindae Officinalis, the Radix Pulsatillae, Pericarpium Pyri, Radix Osbeckiae Crinitae, Caulis seu radix berberidis virgetori, Fructus Ponciri Trifoliatae (Fructus Ponciri Trifoliatae Immaturus), Caulis Arcangelisiae, Herba Allii bulleyani and Usnea are cleaned, put into appearance In device, add the distilled water of 8～10 times amount, after soaking 5～6 hours, boil 3～4 hours, extract；Again add 6～8 times amount Distilled water, boils 2～3 hours, extracts；Finally, add 4～6 times amount distilled water, heated and boiled 1～2 hours, extract；Merge three Secondary extracting solution, filters, obtains filtrate, and being condensed into relative density at 60 DEG C is the thick paste of 1.10～1.13, standby；
(2) Rhizoma Dioscoreae and Radix Stephaniae hemandifoliae are put into container, carry out pulverization process, grind into powder, obtain the fine powder of 180 mesh, standby；
(3) Flos Lonicerae, Radix Rubiae and Fructus Cnidii are cleaned, immerse 5 times amount 80% alcohol solution dipping 1～2 hours, heating carries Taking 3 hours, reclaim ethanol, filter, obtain filtrate, concentration is that at 65 DEG C, relative density is the thick paste of 1.12～1.16, standby；
(4) Herba Iresines Herbstii and Herba Osbeckiae are cleaned, chopping, put into container, twist juice, filter impurity, stay juice standby；
(5) thick paste, fine powder and the juice obtained by above-mentioned steps (1)～(4) is made capsule, obtain described treatment vagina Scorching Chinese medicine preparation.
CN201610624566.0A 2016-07-29 2016-07-29 One treats colpitic Chinese medicine preparation and preparation method Pending CN106075014A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103550645A (en) * 2013-11-14 2014-02-05 林丽娟 Traditional Chinese medicine for treating kysthitis
CN103800503A (en) * 2012-11-12 2014-05-21 梁小琼 Lotion for treating female vaginitis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103800503A (en) * 2012-11-12 2014-05-21 梁小琼 Lotion for treating female vaginitis
CN103550645A (en) * 2013-11-14 2014-02-05 林丽娟 Traditional Chinese medicine for treating kysthitis

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