CN106075000A - A kind of Chinese medicine ointment for treating hemorrhoid and preparation method thereof - Google Patents
A kind of Chinese medicine ointment for treating hemorrhoid and preparation method thereof Download PDFInfo
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- CN106075000A CN106075000A CN201610629169.2A CN201610629169A CN106075000A CN 106075000 A CN106075000 A CN 106075000A CN 201610629169 A CN201610629169 A CN 201610629169A CN 106075000 A CN106075000 A CN 106075000A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
Abstract
The invention discloses a kind of Chinese medicine ointment for treating hemorrhoid and preparation method thereof, described Chinese medicine ointment for treating hemorrhoid includes according to mass fraction: 15~25 parts of Herba Salviae Plebeiaes, 15~25 parts of Galla Chinensiss, 5~15 parts of Sanguis Draxonis, 15~25 Radix Sophorae Flavescentiss, 18~22 parts of Cortex Phellodendris, 15~25 parts of Natrii Sulfas, 15~25 parts of Borneolum Syntheticums and 600~900 parts of ointment bases.The present invention is with Herba Salviae Plebeiae cheap and easy to get, Galla Chinensis, Sanguis Draxonis, Endoconcha Sepiae, Cortex Phellodendri, Radix Sophorae Flavescentis, Natrii Sulfas, Borneolum Syntheticum as raw material, have instant effect, short treating period, no pain, be difficult to recurrence feature, evident in efficacy to internal hemorrhoid, external hemorrhoid, mixed hemorrhoid, the worry of hemorrhoid patients can be solved quickly, thoroughly.
Description
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine ointment for treating hemorrhoid and preparation method thereof.
Background technology
Hemorrhoid are a kind of common anus, and it is to be produced with anal mucosa membrane venous plexus by anal orifice and rectal intestine afterbody
Varicose, and then form one or more vein group, it is apt to occur in the crowd of different age group, and sickness rate increased constantly with the age
Rising, its clinical manifestation is hemorrhage when being defecation, and rectum is deviate from, swollen and ache.Owing to hemorrhoid belong to chronic disease, it forms the cycle relatively
Long, and cause the reason of hemorrhoid in daily life a lot, and complex, the worst living habit and physiology are asked
Topic all may cause hemorrhoid.
The modes such as freezing commonly used to hemorrhoid treating at present, laser, operation and various medicines.Freezing, laser and operation
Treatment brings very big inconvenience, particularly operative treatment to bring body function to injure patient to hemorrhoid patients, above to hemorrhoid
Treatment is all to cut the treatment of Folium Allii tuberosi formula, it is impossible to removes morbidity root, easily recurs, do not reach the purpose of radical cure after healing.
Domestic external hemorrhoid pharmacopoeia class is various, treatment hemorrhoid external application Chinese medicine mainly have suppository, ointment, lotion, tincture, patch,
Local injection liquid etc..In the external used medicine of numerous treatment hemorrhoid, suppository and ointment apply convenient, good effect to be subject to because of it
The favor of extensive patients, and suppository takes effect slowly, curative effect is not good enough, therefore, be badly in need of a kind of easy to use, rapid-action, hemorrhoid can be effected a radical cure again
The Chinese medicine ointment for treating hemorrhoid of skin ulcer.
Summary of the invention
It is an object of the invention to provide a kind of instant effect, short treating period, the Chinese medicine ointment for treating hemorrhoid of hemorrhoid can be effected a radical cure again, in order to
Solve prior art is treated the external used medicine drug effect of hemorrhoid slowly, the problem that cannot thoroughly effect a radical cure hemorrhoid.
For achieving the above object, first aspect present invention provides a kind of Chinese medicine ointment for treating hemorrhoid.Specifically, these Chinese medicine hemorrhoid
Ointment includes according to mass fraction: 15~25 parts of Herba Salviae Plebeiaes, 15~25 parts of Galla Chinensiss, 5~15 parts of Sanguis Draxonis, 15~25 Radix Sophorae Flavescentiss, 15
~25 parts of Natrii Sulfas, 15~25 parts of Borneolum Syntheticums and 600~900 parts of ointment bases.
Preferably, described Chinese medicine ointment for treating hemorrhoid also includes 15~25 portions of Endoconcha Sepiaes and 15~25 parts of Huangs according to mass fraction
Cypress.
Preferably, described Chinese medicine ointment for treating hemorrhoid includes according to mass fraction: 18~22 parts of Herba Salviae Plebeiaes, 18~22 parts five times
Son, 8~12 parts of Sanguis Draxonis, 18~22 portions of Endoconcha Sepiaes, 18~22 portions of Cortex Phellodendris, 18~22 Radix Sophorae Flavescentiss, 18~22 parts of Natrii Sulfas, 18~22 parts of ice
Sheet and 700~800 parts of ointment bases.
Preferably, described Chinese medicine ointment for treating hemorrhoid includes according to mass fraction: 20 parts of Herba Salviae Plebeiaes, 20 parts of Galla Chinensiss, 10 parts of blood
Exhaust, 20 parts of Endoconcha Sepiaes, 20 parts of Cortex Phellodendris, 20 Radix Sophorae Flavescentiss, 20 parts of Natrii Sulfas, 20 parts of Borneolum Syntheticums and 750 parts of ointment bases.
Preferably, described ointment base is vaseline.
Second aspect present invention provides the preparation method of a kind of Chinese medicine ointment for treating hemorrhoid.Specifically, described method include with
Lower step:
One, by Herba Salviae Plebeiae, Galla Chinensis, Sanguis Draxonis, Endoconcha Sepiae, Cortex Phellodendri and Radix Sophorae Flavescentis, pulverize and sieve rear mix homogeneously, obtain medicated powder
Mixture;
Two, after being mixed homogeneously with ointment base by step one gained medicinal powder mixture, it is heated to 100~140 DEG C, insulation
After 0.5~2.5h, naturally cool to 40~50 DEG C;
Three, the mixture after cooling down in step 2 adds the Natrii Sulfas after pulverizing and Borneolum Syntheticum, stirs, in i.e. preparing
Medicine ointment for treating hemorrhoid.
Preferably, the aperture sieved in described step one is 150~300 mesh.
Preferably, 200 mesh sieves are all crossed after Natrii Sulfas and Borneolum Syntheticum are all pulverized in described step 3.
The inventive method has the advantage that
1, the present invention utilizes Herba Salviae Plebeiae, Galla Chinensis, Sanguis Draxonis, Endoconcha Sepiae, Cortex Phellodendri, Radix Sophorae Flavescentis, Natrii Sulfas, Borneolum Syntheticum to be raw material, system
Preparation Method is simple, and material is prone to obtain, and has low cost, is prone to the feature of large-scale production.
2, Chinese medicine ointment for treating hemorrhoid of the present invention, has antipruritic, heat clearing and damp drying, removing the necrotic tissue and promoting granulation, and analgesic therapy is stopped blooding, and removing the necrotic tissue and promoting granulation is received
The effect held back, evident in efficacy to internal hemorrhoid, external hemorrhoid, mixed hemorrhoid, have no side effect, use safety.
3, Chinese medicine ointment for treating hemorrhoid of the present invention can reach more than 99% to the cure rate of hemorrhoid, and instant effect, short treating period, nothing
Painful, be difficult to recurrence.
4, Chinese medicine ointment for treating hemorrhoid of the present invention bacillus various to skin surface, coccus and fungus have extremely strong inhibitory action, can
Effectively prevent wound infection.
Detailed description of the invention
Following example are used for illustrating the present invention, but are not limited to the scope of the present invention.
Embodiment 1
The preparation method of the present embodiment Chinese medicine ointment for treating hemorrhoid, sequentially includes the following steps:
One, by Herba Salviae Plebeiae, Galla Chinensis, Sanguis Draxonis, Endoconcha Sepiae, Cortex Phellodendri and Radix Sophorae Flavescentis, mix homogeneously after 300 mesh sieves was pulverized,
To medicinal powder mixture;
Two, after being mixed homogeneously with ointment base by step one gained medicinal powder mixture, it is heated to 110 DEG C, after insulation 1h, from
So it is cooled to 50 DEG C;
Three, the mixture after cooling down in step 2 adds Natrii Sulfas and the Borneolum Syntheticum pulverizing 200 mesh sieves, stirs,
I.e. prepare Chinese medicine ointment for treating hemorrhoid.
Embodiment 2
The preparation method of the present embodiment Chinese medicine ointment for treating hemorrhoid, sequentially includes the following steps:
One, by Herba Salviae Plebeiae, Galla Chinensis, Sanguis Draxonis, Endoconcha Sepiae, Cortex Phellodendri and Radix Sophorae Flavescentis, mix homogeneously after 150 mesh sieves was pulverized,
To medicinal powder mixture;
Two, after being mixed homogeneously with ointment base by step one gained medicinal powder mixture, it is heated to 140 DEG C, after insulation 2h, from
So it is cooled to 46 DEG C;
Three, the mixture after cooling down in step 2 adds Natrii Sulfas and the Borneolum Syntheticum pulverizing 200 mesh sieves, stirs,
I.e. prepare Chinese medicine ointment for treating hemorrhoid.
Embodiment 3
The preparation method of the present embodiment Chinese medicine ointment for treating hemorrhoid, sequentially includes the following steps:
One, by Herba Salviae Plebeiae, Galla Chinensis, Sanguis Draxonis, Endoconcha Sepiae, Cortex Phellodendri and Radix Sophorae Flavescentis, mix homogeneously after 200 mesh sieves was pulverized,
To medicinal powder mixture;
Two, after being mixed homogeneously with ointment base by step one gained medicinal powder mixture, it is heated to 100 DEG C, after insulation 2.5h,
Naturally cool to 48 DEG C;
Three, the mixture after cooling down in step 2 adds Natrii Sulfas and the Borneolum Syntheticum pulverizing 200 mesh sieves, stirs,
I.e. prepare Chinese medicine ointment for treating hemorrhoid.
Embodiment 4
The preparation method of the present embodiment Chinese medicine ointment for treating hemorrhoid, sequentially includes the following steps:
One, by Herba Salviae Plebeiae, Galla Chinensis, Sanguis Draxonis, Endoconcha Sepiae, Cortex Phellodendri and Radix Sophorae Flavescentis, mix homogeneously after 270 mesh sieves was pulverized,
To medicinal powder mixture;
Two, after being mixed homogeneously with ointment base by step one gained medicinal powder mixture, it is heated to 130 DEG C, after insulation 1.5h,
Naturally cool to 40 DEG C;
Three, the mixture after cooling down in step 2 adds Natrii Sulfas and the Borneolum Syntheticum pulverizing 200 mesh sieves, stirs,
I.e. prepare Chinese medicine ointment for treating hemorrhoid.
Embodiment 5
The preparation method of the present embodiment Chinese medicine ointment for treating hemorrhoid, sequentially includes the following steps:
One, by Herba Salviae Plebeiae, Galla Chinensis, Sanguis Draxonis, Endoconcha Sepiae, Cortex Phellodendri and Radix Sophorae Flavescentis, mix homogeneously after 250 mesh sieves was pulverized,
To medicinal powder mixture;
Two, after being mixed homogeneously with ointment base by step one gained medicinal powder mixture, it is heated to 120 DEG C, after insulation 0.5,
Naturally cool to 42 DEG C;
Three, the mixture after cooling down in step 2 adds Natrii Sulfas and the Borneolum Syntheticum pulverizing 200 mesh sieves, stirs,
I.e. prepare Chinese medicine ointment for treating hemorrhoid.
Hemorrhoid treatment effect: internal hemorrhoid, anus is painless, has blood in stool, and secretions is many, pruritus;External hemorrhoid, scorching hot pain, to have blood in stool, hemorrhoid block takes off
Go out;Mixed hemorrhoid, proctalgia, to have blood in stool, prolapse of hemorrhoid is outside anal orifice, and mucus is excessive.
Thoroughly cure: above clinical symptoms all disappears, without recurrence in half a year;
Evident in efficacy: above clinical symptoms all disappears;
Effective: above clinical symptoms partial disappearance;
Invalid: to have no and be clearly better.
Choose 200 hemorrhoid patients, use the Chinese medicine ointment for treating hemorrhoid that the method for embodiment 1~5 prepares respectively, its
In, patients with mild 120 people moderate patient 50 people, severe patient 30 people.
The Chinese medicine ointment for treating hemorrhoid that 200 hemorrhoid patients use the present invention is the most each the most once, after 7 days, after 14 days and 21 days
After treatment effect, and use this product to cure the recovery from illness patient after latter 1 year to pay a return visit, add up relapse rate.
The Chinese medicine ointment for treating hemorrhoid that table 1 embodiment 1~5 the prepares curative effect to different patients
From table 1 it follows that hemorrhoid patients uses the Chinese medicine ointment for treating hemorrhoid that embodiment 1~5 prepares, first treatment
The thorough cure rate of journey is about 25%, and patient evident in efficacy is 30~40%, and refractory patient is less than 2.5%.And hemorrhoid patients
It is gradually increased along with patient is thoroughly cured in the increase using the course for the treatment of, uses the Chinese medicine hemorrhoid that the embodiment of the present invention 1~5 prepares
After three courses for the treatment of of ointment, cure rate is up to about 60%, pays a return visit using this product thoroughly to cure patient, its recurrence after 1 year
Rate is 0%, and therapeutic effect far surpasses existing product.
By stool diluent uniform application on beef extract-peptone agar culture medium, it is placed in 37 DEG C of incubators cultivation
24h.Take 1g above-mentioned Chinese medicine ointment for treating hemorrhoid to mix with sterilized water and be settled to 4ml, utilize liquid-transfering gun to draw 100 μ L and drop to Carnis Bovis seu Bubali cream
In the Oxford cup placed on peptone agar culture medium, after 6-12 hour, observe the presence or absence and greatly of inhibition zone near added sample well
Little.
The Chinese medicine ointment for treating hemorrhoid that table 2 embodiment 1~5 the prepares suppression situation to stool flora
From Table 2, it can be seen that the Chinese medicine ointment for treating hemorrhoid of the embodiment of the present invention 1~5 preparation, antibacterial circle diameter is all at 2cm
Left and right, shows that the Chinese medicine ointment for treating hemorrhoid that embodiment 1~5 prepares has good inhibition to human body stool flora, and
There is the effect of long-acting bacteriostatic.
The Chinese medicine ointment for treating hemorrhoid of the present invention, can effectively prevent wound infection, further promote the healing of hemorrhoid wound, from
And ensure that the worry of releasing hemorrhoid patients quick, efficient.
Although, the present invention is described in detail to have used general explanation and specific embodiment, but at this
On the basis of invention, can make some modifications or improvements it, this will be apparent to those skilled in the art.Therefore,
These modifications or improvements without departing from theon the basis of the spirit of the present invention, belong to the scope of protection of present invention.
Claims (8)
1. a Chinese medicine ointment for treating hemorrhoid, it is characterised in that: described Chinese medicine ointment for treating hemorrhoid includes according to mass fraction: 15~25 parts of litchis
Branch grass, 15~25 parts of Galla Chinensiss, 5~15 parts of Sanguis Draxonis, 15~25 Radix Sophorae Flavescentiss, 15~25 parts of Natrii Sulfas, 15~25 parts of Borneolum Syntheticums and 600~
900 parts of ointment bases.
Chinese medicine ointment for treating hemorrhoid the most according to claim 1, it is characterised in that: described Chinese medicine ointment for treating hemorrhoid is according to mass fraction
Also include 15~25 portions of Endoconcha Sepiaes and 15~25 portions of Cortex Phellodendris.
Chinese medicine ointment for treating hemorrhoid the most according to claim 2, it is characterised in that: described Chinese medicine ointment for treating hemorrhoid is according to mass fraction
Including: 18~22 parts of Herba Salviae Plebeiaes, 18~22 parts of Galla Chinensiss, 8~12 parts of Sanguis Draxonis, 18~22 portions of Endoconcha Sepiaes, 18~22 portions of Cortex Phellodendris, 18
~22 Radix Sophorae Flavescentiss, 18~22 parts of Natrii Sulfas, 18~22 parts of Borneolum Syntheticums and 700~800 parts of ointment bases.
Chinese medicine ointment for treating hemorrhoid the most according to claim 3, it is characterised in that: described Chinese medicine ointment for treating hemorrhoid is according to mass fraction
Including: 20 parts of Herba Salviae Plebeiaes, 20 parts of Galla Chinensiss, 10 parts of Sanguis Draxonis, 20 parts of Endoconcha Sepiaes, 20 parts of Cortex Phellodendris, 20 Radix Sophorae Flavescentiss, 20 parts of Natrii Sulfas, 20 parts
Borneolum Syntheticum and 750 parts of ointment bases.
5. according to the Chinese medicine ointment for treating hemorrhoid described in claim any one of claim 1-4, it is characterised in that: described ointment base
Matter is vaseline.
6. the preparation method of a Chinese medicine ointment for treating hemorrhoid, it is characterised in that said method comprising the steps of:
One, by Herba Salviae Plebeiae, Galla Chinensis, Sanguis Draxonis, Endoconcha Sepiae, Cortex Phellodendri and Radix Sophorae Flavescentis, pulverize and sieve rear mix homogeneously, obtain medicated powder mixing
Thing;
Two, after being mixed homogeneously with ointment base by step one gained medicinal powder mixture, be heated to 100~140 DEG C, insulation 0.5~
After 2.5h, naturally cool to 40~50 DEG C;
Three, the mixture after cooling down in step 2 adds the Natrii Sulfas after pulverizing and Borneolum Syntheticum, stirs, i.e. prepare Chinese medicine hemorrhoid
Skin ulcer ointment.
The preparation method of Chinese medicine ointment for treating hemorrhoid the most according to claim 6, it is characterised in that: described step one is sieved
Aperture be 150~300 mesh.
The preparation method of Chinese medicine ointment for treating hemorrhoid the most according to claim 6, it is characterised in that: in described step 3 Natrii Sulfas and
Borneolum Syntheticum all crosses 200 mesh sieves after all pulverizing.
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CN107753693A (en) * | 2017-07-27 | 2018-03-06 | 青岛海芬健康产业科技有限公司 | A kind of anti-inflammation acne cream |
CN107823086A (en) * | 2017-11-29 | 2018-03-23 | 旮旯生活(成都)健康管理有限公司 | A kind of cleaning combination for being used to clean anus and anal skin |
CN112999339A (en) * | 2019-12-19 | 2021-06-22 | 陕西康乐实业有限公司 | Lysozyme gel and preparation method and application thereof |
CN114668825A (en) * | 2022-03-15 | 2022-06-28 | 贵州绿太阳制药有限公司 | Oil-in-water ointment for treating skin hemorrhoid and its preparation method |
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CN112999339A (en) * | 2019-12-19 | 2021-06-22 | 陕西康乐实业有限公司 | Lysozyme gel and preparation method and application thereof |
CN114668825A (en) * | 2022-03-15 | 2022-06-28 | 贵州绿太阳制药有限公司 | Oil-in-water ointment for treating skin hemorrhoid and its preparation method |
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