CN106073929A - It is applicable to spring percussion device and the striking method of animal foot Skeletal muscle injury - Google Patents

It is applicable to spring percussion device and the striking method of animal foot Skeletal muscle injury Download PDF

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Publication number
CN106073929A
CN106073929A CN201610388845.1A CN201610388845A CN106073929A CN 106073929 A CN106073929 A CN 106073929A CN 201610388845 A CN201610388845 A CN 201610388845A CN 106073929 A CN106073929 A CN 106073929A
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China
Prior art keywords
spring
cylinder
skeletal muscle
applicable
animal
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Pending
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CN201610388845.1A
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Chinese (zh)
Inventor
陈疾忤
孙亚英
郭诗哲
刘少华
智云龙
张鹏
吴向东
方宏伟
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Huashan Hospital of Fudan University
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Huashan Hospital of Fudan University
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Priority to CN201610388845.1A priority Critical patent/CN106073929A/en
Publication of CN106073929A publication Critical patent/CN106073929A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D1/00Surgical instruments for veterinary use

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Percussive Tools And Related Accessories (AREA)

Abstract

The invention discloses a kind of spring percussion device being applicable to animal foot Skeletal muscle injury and striking method, described animal foot Skeletal muscle injury beating device includes cylinder, support, support platform and animal fixing device;Described support one end is connected with supporting platform, and the other end is connected with cylinder upper end;Described animal fixing device is arranged between support platform and cylinder;Spring beating unit it is provided with in described cylinder.The spring percussion device being applicable to animal foot Skeletal muscle injury of the present invention uses spring design, and with carrying graduated transparent tube that blow energy is labeled, it is ensured that the accuracy of blow energy value.

Description

It is applicable to spring percussion device and the striking method of animal foot Skeletal muscle injury
Technical field
The invention belongs to medical experiment apparatus field, be specifically related to a kind of spring being applicable to animal foot Skeletal muscle injury Formula percussion device and striking method.
Background technology
Skeletal muscle injury is one of common injury in motion, in the injury types of various sports events, muscle injury Shared ratio is the highest, and its incidence rate accounts for the 10%~55% of athletic injury sum, wherein contusion injuries and the incidence rate of tension injury Account for more than 90%.Skeletal muscle contusion injuries is that muscle suffers, caused by the compressing violence of direct passivity, multiple to be born in antagonism motion item In mesh, quadriceps femoris and gastrocnemius are the predilection sites of skeletal muscle contusion injuries.Owing to after damage, muscle fiber is destroyed, produce Microcirculatory disorder and the infiltration of inflammatory cell and the organization of hematoma etc. of muscular tissue, to athletic motor capacity, motion longevity Life all constitutes potential threat.Although muscle injury can be repaired by anathrepsis, but the 26S Proteasome Structure and Function of muscle Not necessarily can return to one's perfect health.The damage of skeletal muscle can have a strong impact on the contractile function of skeletal muscle, destroys myofiber plasma membrane and base The integrity of counterdie, and ultimately cause the death of cell, thus cause the further damage of skeletal muscle.Lead in sports medical science research In territory, the research of Skeletal muscle injury pathomechanism and the discussion of prevention, treatment and measure of rehabilitation always are focus.
In order to deepen the understanding to Skeletal muscle injury, probe into Skeletal muscle injury, especially the occurrence condition of contusion injuries, skeleton The mechanism of muscle injury, Fibrotic inducement and repairing condition after Skeletal muscle injury, we need to carry out Research of Animal Model for Study. The contusion injuries model of animal is widely used in the research of Skeletal muscle injury, but modeling means exist certain defect at present.At present Conventional Skeletal muscle injury modeling method is that contusion injuries, i.e. weight injure by a crashing object.Conventional model animal has mice, rat, and rabbit. Injuring method by a crashing object is: after model animal anesthesia, dorsal position gives away one's position muscle;Target muscles is injured by a crashing object along fixation locus with weight, or One wedge is hit transmitter as pounding, is positioned on target muscles, hold pipeline on wedge, make weight along pipeline in wedge shape Freely falling body directly over thing, pounds wedge, and power is transmitted on destination organization by wedge, ultimately causes contusion injuries (such as Fig. 4 institute Show).There are problems in existing modeling method, as needed many people to complete: fixed model animal, throws away weight, fixed-piping, operation Weight etc.;Confounding Factor is many: cannot ensure that weight height is completely the same, and weight and wedge there may be friction, cause modeling Repeatable poor.
So, a kind of contusion injuries beating device need to be designed, it is ensured that the repeatability of experiment, save manpower.
Summary of the invention
It is an object of the invention to overcome the deficiencies in the prior art, it is provided that a kind of animal foot Skeletal muscle injury of being applicable to Spring percussion device and striking method.
It is an object of the invention to be achieved through the following technical solutions:
The invention provides a kind of spring percussion device being applicable to animal foot Skeletal muscle injury, including cylinder, prop up Frame, support platform and animal fixing device;Described support one end is connected with supporting platform, and the other end is connected with cylinder upper end;Described dynamic Thing fixing device is arranged between support platform and cylinder;Spring beating unit it is provided with in described cylinder.
Preferably, described cylinder top is closed, bottom end opening;Described top central authorities arrange a through hole.
Preferably, described spring beating unit includes spring, handle and wedge;Described handle one end is provided with pedestal, The other end is provided with handle head, and described spring is arranged between pedestal and handle head;Described pedestal is connected with wedge.Described hands Button is Rubber end or finger ring, facilitates hand-held tractive.
Preferably, described base height is 1cm;Wedge height is 5cm, and weight is less than 20g.
Preferably, the described a diameter of 0.6cm of wedge bottom face (hitting Mus) or 1.8cm (hitting rabbit).
Preferably, described pedestal is cylindrical, and pedestal lateral wall is provided with screw channel;Described wedge top is cylindrical, Bottom is turbination, and the medial wall on wedge top is provided with the screw thread matched with pedestal screw channel.It is threaded connection, makes Chuck top is consistent with wedge tip height.
Preferably, described handle and wedge all use light material to prepare;Described wedge is hollow structure.
Preferably, described handle and wedge all use plastics to prepare, and handle and wedge gross weight are less than 50g.So, Spring need to provide the strength of 0.48 newton to resist, and i.e. initial deformation amount 0.384cm, is negligible.So this initial shape The energy variation that variable is caused is negligible.
Preferably, described in be provided with handle one end of handle head and stretched out by the through hole of cylinder, make handle head be positioned on cylinder Side.
Preferably, described handle is hollow pipe for connecting the middle part of handle head and pedestal, and diameter is less than 0.5cm, Length 50cm, weight is less than 20g.
Preferably, described spring one end and cylinder top are fixing to be connected, or described handle stretch out cylinder in place of arrange convex Rising, described projection is close to cylinder upper surface;Described spring diameter is 4.5cm, a length of 45cm, and coefficient of elasticity K is 125N/m.
Preferably, the diameter of described projection is more than through hole.
Preferably, described spring is identical with the diameter of pedestal.
Preferably, there is scale described cylinder lateral wall, and barrel lenght is 50cm, a diameter of 5cm.
Preferably, described cylinder scale is energy unit's joule (J), and scale is 0-10 joule from bottom to top.
From spring deformation coefficient: often compress 4cm, erg-ten energy can be stored.For model animal, minimum blunt Contusion energy range is at 3.0-3.7 joule, therefore needs 12-14.8cm spring deformation.
Spring-handle association rotates the total length of twist-on wedge rear spring and wedge should keep one with long tube length degree Cause, range of error 0.5cm.
Preferably, described support includes fixed bracket, jack column or folding bracket.
Present invention also offers the striking method of a kind of spring percussion device being applicable to animal foot Skeletal muscle injury, Comprise the following steps:
Laboratory animal is fixed in animal fixing device, regulates the height of cylinder and fix;
According to the scale value selected, handle button makes wedge bottom be parallel at selected scale value straight up, Release handle head allows spring recover elastic deformation, makes wedge striking experiment animal;
?.
Compared with prior art, the present invention has a following beneficial effect:
1, the assay reproducibility of the spring percussion device being applicable to animal foot Skeletal muscle injury of the present invention is good, and Complete without many people, manpower can be saved.
2, the spring percussion device being applicable to animal foot Skeletal muscle injury of the present invention can be accurately by the most dynamic for power conduction Thing treats damage tissue.
3, the spring percussion device being applicable to animal foot Skeletal muscle injury of the present invention uses spring design, and with carrying Blow energy is labeled by graduated transparent tube, it is ensured that the accuracy of blow energy value.
Accompanying drawing explanation
By the detailed description non-limiting example made with reference to the following drawings of reading, the further feature of the present invention, Purpose and advantage will become more apparent upon:
Fig. 1 is the schematic diagram that the present invention is applicable to the spring percussion device of animal foot Skeletal muscle injury;
Fig. 2 is the spring beating unit signal that the present invention is applicable to the spring percussion device of animal foot Skeletal muscle injury Figure;
Fig. 3 is the wedge schematic diagram that the present invention is applicable to the spring percussion device of animal foot Skeletal muscle injury;Figure A left side is the wedge of base diameter 1.8cm;The figure right side is the wedge of base diameter 0.6cm;
Fig. 4 is Skeletal muscle injury modeling method schematic diagram of the prior art;
Wherein, 1-cylinder;2-spring beating unit;3-support;4-supports platform;5-spring;6-pedestal;7-handle head;8- Weight;9-wedge.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is described in detail.Following example will assist in the technology of this area Personnel are further appreciated by the present invention, but limit the present invention the most in any form.It should be pointed out that, the ordinary skill to this area For personnel, without departing from the inventive concept of the premise, it is also possible to make some deformation and improvement.These broadly fall into the present invention Protection domain.
Embodiment 1
Present embodiments provide a kind of spring percussion device being applicable to animal foot Skeletal muscle injury, such as Fig. 1 and Fig. 2 Shown in, including cylinder 1, support 3, support platform 4 and animal fixing device;Described support 3 one end is connected with supporting platform 4, the other end It is connected with cylinder 1 upper end;Described animal fixing device is arranged between support platform 4 and cylinder 1;It is provided with bullet in described cylinder 1 Spring beating unit 2.
Described cylinder 1 top closure, bottom end opening;Described top central authorities arrange a through hole.
Described spring beating unit 2 includes spring 5, handle and wedge 9 (as shown in Figure 3);Described handle one end is arranged Having pedestal 6, the other end is provided with handle head 7, and described spring 5 is arranged between pedestal 6 and handle head 7;Described pedestal 6 and wedge shape Block 9 connects.Described handle head 7 is Rubber end or finger ring, facilitates hand-held tractive.
Described pedestal 6 height is 1cm;Wedge 9 height is 5cm, and weight is less than 20g.
The described wedge 9 a diameter of 0.6cm of bottom face (hitting Mus) or 1.8cm (hitting rabbit).
Described pedestal 6 is cylindrical, and pedestal 6 lateral wall is provided with screw channel;Described wedge 9 top is cylindrical, bottom For turbination, the medial wall on wedge 9 top is provided with the screw thread matched with pedestal 6 screw channel.It is threaded connection, makes base Seat 6 tops are consistent with wedge 9 tip height.
Described handle and wedge 9 all use light material to prepare;Described wedge 9 is hollow structure.
Described handle and wedge 9 all use plastics to prepare, and handle and wedge 9 gross weight are less than 50g.So, spring The strength that need to provide 0.48 newton is resisted, and i.e. initial deformation amount 0.384cm, is negligible.So this initial deformation amount The energy variation caused is negligible.
Described handle one end being provided with handle head 7 is stretched out by the through hole of cylinder 1, makes handle head 7 be positioned at above cylinder 1.
Described handle is hollow pipe for connecting the middle part of handle head 7 and pedestal 6, and diameter is less than 0.5cm, length 50cm, weight is less than 20g.
Described spring 5 one end and cylinder 1 top are fixing to be connected, or described handle stretch out cylinder 1 in place of projection is set, institute State projection and be close to cylinder 1 upper surface;The described a diameter of 4.5cm of spring 5, a length of 45cm, coefficient of elasticity K is 125N/m.
The diameter of described projection is more than through hole.
Described spring 5 is identical with the diameter of pedestal 6.
There are scale, a length of 50cm of cylinder 1, a diameter of 5cm in described cylinder 1 lateral wall.
Described cylinder 1 scale is energy unit's joule (J), and scale is 0-10 joule from bottom to top.
From spring deformation coefficient: often compress 4cm, erg-ten energy can be stored.For model animal, minimum blunt Contusion energy range is at 3.0-3.7 joule, therefore needs 12-14.8cm spring deformation.
Spring-handle association rotates the total length of twist-on wedge rear spring and wedge should keep one with long tube length degree Cause, range of error 0.5cm.
Described cylinder 1 is prepared for transparent material.
Described support 3 includes fixed bracket, jack column or folding bracket.
Prepared by the present embodiment is applicable to the striking method of the spring percussion device of animal foot Skeletal muscle injury, including Following steps:
Laboratory animal is fixed in animal fixing device, regulates the height of cylinder 1 and fix;
According to the scale value selected, handle button 7 makes wedge 9 bottom be parallel to selected scale value straight up Place, release handle 7 allows spring 5 recover elastic deformation, makes wedge 9 striking experiment animal;
?.
In sum, the spring percussion device being applicable to animal foot Skeletal muscle injury of the present invention has the most excellent Point: assay reproducibility is good, and complete without many people, manpower can be saved;Accurately power conduction to animal can be treated damage tissue;Adopt Design with spring, and with carrying graduated transparent tube that blow energy is labeled, it is ensured that the accuracy of blow energy value.
The concrete application approach of the present invention is a lot, and the above is only the preferred embodiment of the present invention.It should be pointed out that, above Embodiment is merely to illustrate the present invention, and is not limited to protection scope of the present invention.Common skill for the art For art personnel, under the premise without departing from the principles of the invention, it is also possible to make some improvement, these improvement also should be regarded as this Bright protection domain.

Claims (10)

1. the spring percussion device being applicable to animal foot Skeletal muscle injury, it is characterised in that include cylinder, support, Support platform and animal fixing device;Described support one end is connected with supporting platform, and the other end is connected with cylinder upper end;Described animal Fixing device is arranged between support platform and cylinder;Spring beating unit it is provided with in described cylinder;Described cylinder is by transparent material Material preparation.
It is applicable to the spring percussion device of animal foot Skeletal muscle injury the most as claimed in claim 1, it is characterised in that institute State cylinder top to close, bottom end opening;Described cylinder top central authorities arrange a through hole.
It is applicable to the spring percussion device of animal foot Skeletal muscle injury the most as claimed in claim 2, it is characterised in that institute State spring beating unit and include spring, handle and wedge;Described handle one end is provided with pedestal, and the other end is provided with handle Head, described spring is arranged between pedestal and handle head;Described pedestal is connected with wedge.
It is applicable to the spring percussion device of animal foot Skeletal muscle injury the most as claimed in claim 3, it is characterised in that institute Stating pedestal is cylinder, and pedestal lateral wall is provided with screw channel;Described wedge top is cylindrical, and bottom is turbination, wedge The medial wall on shape block top is provided with the screw thread matched with pedestal screw channel.
It is applicable to the spring percussion device of animal foot Skeletal muscle injury the most as claimed in claim 3, it is characterised in that institute State handle and wedge all uses light material to prepare;Described wedge is hollow structure.
It is applicable to the spring percussion device of animal foot Skeletal muscle injury the most as claimed in claim 3, it is characterised in that institute State and be provided with handle one end of handle head and stretched out by the through hole of cylinder, make handle head be positioned at above cylinder.
It is applicable to the spring percussion device of animal foot Skeletal muscle injury the most as claimed in claim 3, it is characterised in that institute State that spring one end and cylinder top are fixing to be connected, or described handle stretch out cylinder in place of projection is set, described projection is close to cylinder Body upper surface;Described spring diameter is 4.5cm, a length of 45cm, and coefficient of elasticity K is 125N/m.
It is applicable to the spring percussion device of animal foot Skeletal muscle injury the most as claimed in claim 3, it is characterised in that institute State spring identical with the diameter of pedestal.
Being applicable to the spring percussion device of animal foot Skeletal muscle injury the most as claimed in claim 1 or 2, its feature exists In, there is scale described cylinder lateral wall, and barrel lenght is 50cm, a diameter of 5cm.
10. one kind is hit dress based on the spring being applicable to animal foot Skeletal muscle injury described in any one of claim 1~9 The striking method put, it is characterised in that comprise the following steps:
Laboratory animal is fixed in animal fixing device, regulates the height of cylinder and fix;
According to the scale value selected, handle button makes wedge bottom be parallel to, at selected scale value, unclamp straight up Handle head recovers elastic deformation by spring, makes wedge striking experiment animal;
?.
CN201610388845.1A 2016-06-02 2016-06-02 It is applicable to spring percussion device and the striking method of animal foot Skeletal muscle injury Pending CN106073929A (en)

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CN201610388845.1A CN106073929A (en) 2016-06-02 2016-06-02 It is applicable to spring percussion device and the striking method of animal foot Skeletal muscle injury

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Application Number Priority Date Filing Date Title
CN201610388845.1A CN106073929A (en) 2016-06-02 2016-06-02 It is applicable to spring percussion device and the striking method of animal foot Skeletal muscle injury

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109717982A (en) * 2019-03-15 2019-05-07 河南医学高等专科学校 A kind of percussion device causing the damage of minitype animal experiment brainpan

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2044871U (en) * 1988-08-19 1989-09-27 湖南医科大学附一院 External trigger
CN201341952Y (en) * 2009-02-11 2009-11-11 天津医科大学总医院 Free falling type small-sized biological trauma machine
CN101779987A (en) * 2010-03-16 2010-07-21 胡建中 Acute spinal cord injury animal model modeling impactor
CN202105043U (en) * 2011-05-30 2012-01-11 中国人民解放军第三军医大学 Device for building spinal cord injury or muscle contusion and laceration animal models
CN102379752A (en) * 2011-08-22 2012-03-21 中南大学湘雅医院 Automatic electric-control gravity-type striker for constructing acute spinal cord injury animal model
CN202637175U (en) * 2012-04-17 2013-01-02 广州军区广州总医院 Impactor for building closed liver trauma model

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2044871U (en) * 1988-08-19 1989-09-27 湖南医科大学附一院 External trigger
CN201341952Y (en) * 2009-02-11 2009-11-11 天津医科大学总医院 Free falling type small-sized biological trauma machine
CN101779987A (en) * 2010-03-16 2010-07-21 胡建中 Acute spinal cord injury animal model modeling impactor
CN202105043U (en) * 2011-05-30 2012-01-11 中国人民解放军第三军医大学 Device for building spinal cord injury or muscle contusion and laceration animal models
CN102379752A (en) * 2011-08-22 2012-03-21 中南大学湘雅医院 Automatic electric-control gravity-type striker for constructing acute spinal cord injury animal model
CN202637175U (en) * 2012-04-17 2013-01-02 广州军区广州总医院 Impactor for building closed liver trauma model

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109717982A (en) * 2019-03-15 2019-05-07 河南医学高等专科学校 A kind of percussion device causing the damage of minitype animal experiment brainpan
CN109717982B (en) * 2019-03-15 2020-07-24 河南医学高等专科学校 Striking device for causing brain injury of small experimental animal

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Application publication date: 20161109