CN106073928A - Free fall type animal contusion injuries beating device and striking method - Google Patents
Free fall type animal contusion injuries beating device and striking method Download PDFInfo
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- CN106073928A CN106073928A CN201610388844.7A CN201610388844A CN106073928A CN 106073928 A CN106073928 A CN 106073928A CN 201610388844 A CN201610388844 A CN 201610388844A CN 106073928 A CN106073928 A CN 106073928A
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- cylinder
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D1/00—Surgical instruments for veterinary use
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Abstract
The invention discloses a kind of free fall type animal contusion injuries beating device and striking method, including spherical weight, support platform, cylinder, support and wedge；Described support one end is connected with supporting platform, and the other end is connected with cylinder upper end；Described cylinder is vertically installed in above support platform；Described wedge is arranged between support platform and cylinder.Power conduction to animal accurately can be treated damage tissue by the animal foot Skeletal muscle injury beating device of the present invention, and assay reproducibility is good, and completes without many people, can save manpower.
Description
Technical field
The invention belongs to medical experiment apparatus field, be specifically related to a kind of free fall type animal contusion injuries beating device and beat
Hit method.
Background technology
Skeletal muscle injury is one of common injury in motion, in the injury types of various sports events, muscle injury
Shared ratio is the highest, and its incidence rate accounts for the 10%～55% of athletic injury sum, wherein contusion injuries and the incidence rate of tension injury
Account for more than 90%.Skeletal muscle contusion injuries is that muscle suffers, caused by the compressing violence of direct passivity, multiple to be born in antagonism motion item
In mesh, quadriceps femoris and gastrocnemius are the predilection sites of skeletal muscle contusion injuries.Owing to after damage, muscle fiber is destroyed, produce
Microcirculatory disorder and the infiltration of inflammatory cell and the organization of hematoma etc. of muscular tissue, to athletic motor capacity, motion longevity
Life all constitutes potential threat.Although muscle injury can be repaired by anathrepsis, but the 26S Proteasome Structure and Function of muscle
Not necessarily can return to one's perfect health.The damage of skeletal muscle can have a strong impact on the contractile function of skeletal muscle, destroys myofiber plasma membrane and base
The integrity of counterdie, and ultimately cause the death of cell, thus cause the further damage of skeletal muscle.Lead in sports medical science research
In territory, the research of Skeletal muscle injury pathomechanism and the discussion of prevention, treatment and measure of rehabilitation always are focus.
In order to deepen the understanding to Skeletal muscle injury, probe into Skeletal muscle injury, especially the occurrence condition of contusion injuries, skeleton
The mechanism of muscle injury, Fibrotic inducement and repairing condition after Skeletal muscle injury, we need to carry out Research of Animal Model for Study.
The contusion injuries model of animal is widely used in the research of Skeletal muscle injury, but modeling means exist certain defect at present.At present
Conventional Skeletal muscle injury modeling method is that contusion injuries, i.e. weight injure by a crashing object.Conventional model animal has mice, rat, and rabbit.
Injuring method by a crashing object is: after model animal anesthesia, dorsal position gives away one's position muscle；Target muscles is injured by a crashing object along fixation locus with weight, or
One wedge is hit transmitter as pounding, is positioned on target muscles, hold pipeline on wedge, make weight along pipeline in wedge shape
Freely falling body directly over thing, pounds wedge, and power is transmitted on destination organization by wedge, ultimately causes contusion injuries (such as Fig. 3 institute
Show).There are problems in existing modeling method, as needed many people to complete: fixed model animal, throws away weight, fixed-piping, operation
Weight etc.；Confounding Factor is many: cannot ensure that weight height is completely the same, and weight and wedge there may be friction, cause modeling
Repeatable poor.
So, a kind of contusion injuries beating device need to be designed, it is ensured that the repeatability of experiment, save manpower.
Summary of the invention
It is an object of the invention to overcome the deficiencies in the prior art, it is provided that a kind of free fall type animal contusion injuries beating device
And striking method.
It is an object of the invention to be achieved through the following technical solutions:
The invention provides a kind of free fall type animal contusion injuries beating device and striking method, including spherical weight, prop up
Support platform, cylinder, support and wedge；Described support one end is connected with supporting platform, and the other end is connected with cylinder upper end；Described cylinder
It is vertically installed in above support platform；Described wedge is arranged between support platform and cylinder.
Preferably, described barrel wall is provided with the ballast support device laterally across cylinder.
Preferably, described animal support means is for supporting screw, latch or strip pad.
Preferably, the vertical dimension of described animal support means and cylinder top is equal to the radius of spherical weight.
Preferably, described barrel lenght is 103cm.
Preferably, the distance that described support and cylinder junction distance support platform is 100cm.
Preferably, described support includes fixed bracket, jack column or folding bracket.
Preferably, described support includes the transverse process bar of the mobile jib parallel with cylinder and band T-Ring, and transverse process bar is vertical with mobile jib
Connect, T-Ring is provided with the screw threadeded with it.Cylinder is made to be fixed on T-Ring by screw, and the height of adjustable cylinder
Degree.
Preferably, the radius of described spherical weight is 3cm, and weight is 320g or 160g.
Preferably, described wedge is turbination, and upper bottom surface radius is 4cm, and bottom surface radius is 2cm or 0.5cm, high
For 3cm.
All parts, except spherical weight is metal material, wedge is outside timber or metal material, and remainder can be all
Metal, plastics or wooden.
When, in time hitting animal and be Mus, selecting weight is the spherical weight of 320g, and bottom surface radius is the wedge of 2cm.
Spherical weight falls offer 3.14 Joule energies from 1 meter high, and this breaks energy is the required energy of rabbit skeletal muscle damage that document is supported
Amount.
When, in time hitting animal and be rabbit, selecting weight is the spherical weight of 160g, and bottom surface radius is the wedge shape of 0.5cm
Block.Spherical weight falls offer 1.57 Joule energies from 1 meter high, and this breaks energy is that the rat mice skeletal that document is supported is damaged
The required energy of wound.
Present invention also offers a kind of striking method based on described free fall type animal contusion injuries beating device, including
Following steps:
Laboratory animal being fixed on support platform, regulate the height of cylinder and fix, wedge is placed on laboratory animal and treats
Strike is between cylinder, and keeps wedge one end to treat at strike against laboratory animal, and the other end brings out under cylinder
Mouthful；
Spherical weight is put into from cylinder upper inlet, pounds to wedge by cylinder freely falling body, make wedge by power
Conduction to laboratory animal is treated at strike；
?.
Compared with prior art, the present invention has a following beneficial effect:
1, the assay reproducibility of the free fall type animal contusion injuries beating device of the present invention is good, and completes without many people,
Manpower can be saved.
2, power conduction to animal accurately can be treated damage tissue by the free fall type animal contusion injuries beating device of the present invention.
Accompanying drawing explanation
By the detailed description non-limiting example made with reference to the following drawings of reading, the further feature of the present invention,
Purpose and advantage will become more apparent upon:
Fig. 1 is the schematic diagram of free fall type animal contusion injuries beating device of the present invention；
Fig. 2 is the axonometric chart of the free fall type animal contusion injuries beating device of embodiment 1；
Fig. 3 is Skeletal muscle injury modeling method schematic diagram of the prior art；
Wherein, 1-cylinder；2-spherical weight；3-wedge；4-support；5-supports screw；6-screw；7-T-Ring.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is described in detail.Following example will assist in the technology of this area
Personnel are further appreciated by the present invention, but limit the present invention the most in any form.It should be pointed out that, the ordinary skill to this area
For personnel, without departing from the inventive concept of the premise, it is also possible to make some deformation and improvement.These broadly fall into the present invention
Protection domain.
The invention provides a kind of free fall type animal contusion injuries beating device, as depicted in figs. 1 and 2, including spherical heavy
Thing 2, support platform, cylinder 1, support 4 and wedge 5；Described support 4 one end is connected with supporting platform, and the other end is with cylinder 1 upper end even
Connect；Described cylinder 1 is vertically installed in above support platform；Described wedge 3 is arranged between support platform and cylinder 1.
It is provided with the ballast support device laterally across cylinder on described cylinder 1 wall.
Described animal support means is for supporting screw 5, latch or strip pad.
The vertical dimension on described animal support means and cylinder 1 top is equal to the radius of spherical weight 2.
The described a length of 103cm of cylinder 1.
The distance that described support 4 supports platform with cylinder 1 junction distance is 100cm.
Described support 4 includes fixed bracket, jack column or folding bracket.
The radius of described spherical weight 2 is 3cm, and weight is 320g or 160g.
Described wedge 3 is turbination, and upper bottom surface radius is 4cm, and bottom surface radius is 2cm or 0.5cm, a height of 3cm.
All parts, except spherical weight 2 is metal material, wedge 3 is outside timber or metal material, remainder
For metal, plastics or wooden.
The striking method of described free fall type animal contusion injuries beating device, comprises the following steps:
Laboratory animal being fixed on support platform, regulate the height of cylinder 1 and fix, wedge 3 is placed on laboratory animal
Treating that strike is between cylinder 1, and keep wedge 3 one end to treat at strike against laboratory animal, the other end is against cylinder 1 time
Bring out mouth；
Spherical weight 2 is put into from cylinder 1 upper inlet, is pounded to wedge 3 by cylinder 1 freely falling body, make wedge 3
Power conduction is treated at strike to laboratory animal；
?.
Embodiment 1
Present embodiments provide a kind of free fall type animal contusion injuries beating device, as in figure 2 it is shown, include spherical weight 2,
Support platform, cylinder 1, support 4 and wedge 3；Described support 4 one end is connected with supporting platform, and the other end is connected with cylinder 1 upper end；
Described cylinder 1 is vertically installed in above support platform；Described wedge 3 is arranged between support platform and cylinder 1.
It is provided with the ballast support device laterally across cylinder 1 on described cylinder 1 wall.
Described animal support means is for supporting screw 5.
The vertical dimension on described support screw 5 and cylinder 1 top is equal to the radius of spherical weight 2.
The described a length of 103cm of cylinder 1.
The distance that described support 4 supports platform with cylinder 1 junction distance is 100cm.
Described support 4 includes fixed bracket, jack column or folding bracket.
Described support 4 includes the transverse process bar of the mobile jib parallel with cylinder and band T-Ring 7, and transverse process bar is vertical with mobile jib to be connected,
The screw 6 threadeded with it it is provided with on T-Ring 7.Cylinder 1 is made to be fixed on T-Ring by screw 6, and the height of adjustable cylinder
Degree.
The radius of described spherical weight 2 is 3cm, and weight is 320g or 160g.
Described wedge 3 is turbination, and upper bottom surface radius is 4cm, and bottom surface radius is 2cm or 0.5cm, a height of 3cm.
All parts, except spherical weight 2 is metal material, wedge 3 is outside timber or metal material, remainder
For metal, plastics or wooden.
When, in time hitting animal and be Mus, selecting weight is the spherical weight of 320g, and bottom surface radius is the wedge of 2cm.
Spherical weight falls offer 3.14 Joule energies from 1 meter high, and this breaks energy is the required energy of rabbit skeletal muscle damage that document is supported
Amount.
When, in time hitting animal and be rabbit, selecting weight is the spherical weight of 160g, and bottom surface radius is the wedge shape of 0.5cm
Block.Spherical weight falls offer 1.57 Joule energies from 1 meter high, and this breaks energy is that the rat mice skeletal that document is supported is damaged
The required energy of wound.
The striking method of the free fall type animal contusion injuries beating device described in the present embodiment, comprises the following steps:
1, after model animal being anaesthetized, it is positioned on support platform, intends being broken position and be positioned over immediately below nozzle, support platform
It is positioned over level ground；
2, adjust nozzle height, to adapt to be hit the tissue thickness of animal, keep it perpendicular to the ground；
3, hand steered wedge 3, below wedge 3, correspondence breaks position, and it is suitable for reading that top connects cylinder；
4, with screw, correspondence metal ball is stuck in cylinder fixing (now bead center of gravity is suitable for reading with cylinder maintains an equal level) suitable for reading
5, hereafter, reverse the turn of the screw, make bead drop.
6, bead drops after 1 meter, and dropping on the wedge of cylinder end opening, (now bead center of gravity is above cylinder end opening at 3cm.
But due to the high 103cm of cylinder, therefore bead drops 1 meter)；
7, energy is extremely broken position through wedge conduction；
8, terminate.
Power conduction to animal accurately can be treated damage tissue by the free fall type animal contusion injuries beating device of the present embodiment, real
Test favorable repeatability, and complete without many people, manpower can be saved.
The concrete application approach of the present invention is a lot, and the above is only the preferred embodiment of the present invention.It should be pointed out that, above
Embodiment is merely to illustrate the present invention, and is not limited to protection scope of the present invention.Common skill for the art
For art personnel, under the premise without departing from the principles of the invention, it is also possible to make some improvement, these improvement also should be regarded as this
Bright protection domain.
Claims (10)
1. a free fall type animal contusion injuries beating device and striking method, it is characterised in that include spherical weight, support
Platform, cylinder, support and wedge；Described support one end is connected with supporting platform, and the other end is connected with cylinder upper end；Described cylinder hangs down
Directly it is arranged at above support platform；Described wedge is arranged between support platform and cylinder；Described wedge is timber or metal material
Matter.
2. free fall type animal contusion injuries beating device as claimed in claim 1 and striking method, it is characterised in that described cylinder
The ballast support device laterally across cylinder it is provided with on body wall.
3. free fall type animal contusion injuries beating device as claimed in claim 2 and striking method, it is characterised in that described dynamic
Thing support means is for supporting screw, latch or strip pad.
4. free fall type animal contusion injuries beating device as claimed in claim 2 and striking method, it is characterised in that described dynamic
The vertical dimension of thing support means and cylinder top is equal to the radius of spherical weight.
5. free fall type animal contusion injuries beating device as claimed in claim 1 and striking method, it is characterised in that described cylinder
Body length is 103cm.
6. free fall type animal contusion injuries beating device as claimed in claim 1 and striking method, it is characterised in that described
The distance that frame supports platform with cylinder junction distance is 100cm.
7. free fall type animal contusion injuries beating device as claimed in claim 1 and striking method, it is characterised in that described
Frame includes fixed bracket, jack column or folding bracket.
8. free fall type animal contusion injuries beating device as claimed in claim 1 and striking method, it is characterised in that described ball
The radius of shape weight is 3cm, and weight is 320g or 160g.
9. free fall type animal contusion injuries beating device as claimed in claim 1 and striking method device, it is characterised in that described
Wedge is turbination, and upper bottom surface radius is 4cm, and bottom surface radius is 2cm or 0.5cm, a height of 3cm.
10. a striking method based on the free fall type animal contusion injuries beating device described in any one of claim 1～9,
It is characterized in that, comprise the following steps:
Laboratory animal being fixed on support platform, regulate the height of cylinder and fix, wedge is placed on laboratory animal and waits to hit
Being between cylinder, and keep wedge one end to treat at strike against laboratory animal, the other end exports against the lower end of cylinder；
Spherical weight is put into from cylinder upper inlet, pounds to wedge by cylinder freely falling body, make wedge power be conducted
Treat at strike to laboratory animal；
?.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610388844.7A CN106073928A (en) | 2016-06-02 | 2016-06-02 | Free fall type animal contusion injuries beating device and striking method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610388844.7A CN106073928A (en) | 2016-06-02 | 2016-06-02 | Free fall type animal contusion injuries beating device and striking method |
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| Publication Number | Publication Date |
|---|---|
| CN106073928A true CN106073928A (en) | 2016-11-09 |
Family
ID=57447043
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610388844.7A Pending CN106073928A (en) | 2016-06-02 | 2016-06-02 | Free fall type animal contusion injuries beating device and striking method |
Country Status (1)
| Country | Link |
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| CN (1) | CN106073928A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110082199A (en) * | 2018-01-26 | 2019-08-02 | 株式会社岛津制作所 | Percussion device and intrinsic frequency measurement device |
| CN114600790A (en) * | 2022-01-20 | 2022-06-10 | 中国人民解放军西部战区总医院 | Small animal blunt contusion striking system |
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| CN101450005A (en) * | 2007-11-30 | 2009-06-10 | 深圳市北科生物科技有限公司 | Installation method of ventral urgent spinal cord injury animal model |
| CN201341952Y (en) * | 2009-02-11 | 2009-11-11 | 天津医科大学总医院 | Free falling type small-sized biological trauma machine |
| CN201414851Y (en) * | 2009-06-25 | 2010-03-03 | 中国人民解放军第四军医大学 | Animal closed brain injury falling body hitting device |
| CN203576679U (en) * | 2013-11-08 | 2014-05-07 | 中国人民解放军成都军区总医院 | Biological impact machine for small rodents |
| CN104287861A (en) * | 2014-10-31 | 2015-01-21 | 江南大学 | Mouse spinal cord contusion modeling experiment table |
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2016
- 2016-06-02 CN CN201610388844.7A patent/CN106073928A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101450005A (en) * | 2007-11-30 | 2009-06-10 | 深圳市北科生物科技有限公司 | Installation method of ventral urgent spinal cord injury animal model |
| CN201341952Y (en) * | 2009-02-11 | 2009-11-11 | 天津医科大学总医院 | Free falling type small-sized biological trauma machine |
| CN201414851Y (en) * | 2009-06-25 | 2010-03-03 | 中国人民解放军第四军医大学 | Animal closed brain injury falling body hitting device |
| CN203576679U (en) * | 2013-11-08 | 2014-05-07 | 中国人民解放军成都军区总医院 | Biological impact machine for small rodents |
| CN104287861A (en) * | 2014-10-31 | 2015-01-21 | 江南大学 | Mouse spinal cord contusion modeling experiment table |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110082199A (en) * | 2018-01-26 | 2019-08-02 | 株式会社岛津制作所 | Percussion device and intrinsic frequency measurement device |
| CN114600790A (en) * | 2022-01-20 | 2022-06-10 | 中国人民解放军西部战区总医院 | Small animal blunt contusion striking system |
| CN114600790B (en) * | 2022-01-20 | 2023-05-05 | 中国人民解放军西部战区总医院 | Blunt contusion striking system for small animals |
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Application publication date: 20161109 |
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