CN106072113A - Cattle Fructus Lycopersici esculenti electuary - Google Patents
Cattle Fructus Lycopersici esculenti electuary Download PDFInfo
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- CN106072113A CN106072113A CN201610430675.9A CN201610430675A CN106072113A CN 106072113 A CN106072113 A CN 106072113A CN 201610430675 A CN201610430675 A CN 201610430675A CN 106072113 A CN106072113 A CN 106072113A
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- Prior art keywords
- lycopersici esculenti
- fructus lycopersici
- bovis seu
- seu bubali
- adeps bovis
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of of health nutrient field and apply natural food Fructus Lycopersici esculenti, Adeps Bovis seu Bubali, a kind of cattle Fructus Lycopersici esculenti electuary with certain health care functions of Mel synthesis.The Fructus Lycopersici esculenti, the wild Adeps Bovis seu Bubali in Tianshan Mountains and the snow mountain mountain flower Mel that use Xinjiang to produce are raw material, by concentrating, extracting and synthetic technology, the granules beverage organically made by main component organic synthesis, the most often include tomato solids thing 7g, Adeps Bovis seu Bubali extract 1.5g, Mel 1.5g.The present invention is concentrated liquid, dissolved granule, powder or blocks of solid dosage form, provides a kind of low price, convenient transport preservation, taking convenience and crowd to be prone to the beverage accepted for people.Can effectively slow down aging, strengthen body immunity, prevent and suppress cancer, protect cardiovascular and cerebrovascular vessel, prevention and control human prostate's disease and tumor.Improve human body total quality, increase human longevity expected value.
Description
Technical field
The present invention relates to a kind of drinking food product in health nutrient field, be related specifically to apply natural food Fructus Lycopersici esculenti, cattle
Extremely, a kind of cattle Fructus Lycopersici esculenti electuary with certain health care functions of Mel synthesis.
Background technology
Lycopene (Lycopene) is the one of carotenoid, is the strongest a kind of antioxidant, has extremely strong clear
Except the ability of free radical, there is remarkable result to preventing and treating carcinoma of prostate, pulmonary carcinoma, breast carcinoma, uterus carcinoma etc., also prevent cardiovascular and cerebrovascular vessel
Disease, raising effect such as immunity, slow down aging, have the title of plant gold, be described as " new lovers of 21 century health product ".It is
Antioxidant the strongest in nature, its antioxidation is 2 times of beta-carotene, 100 times of VE.Removing human body, " ten thousand is sick
Source "---free radical aspect, the effect of lycopene is more powerful than beta-carotene.
Adeps Bovis seu Bubali is Labiatae Origanum herbaceos perennial, for armaticity spice berry.All have in worldwide with
This is human drugs and the health product of raw material, is a kind of potential natural antibiotics and non-drug growth promoter.American agriculture
The background information of " phytochemistry and the plant species " in portion shows, Adeps Bovis seu Bubali contains more than 30 kind of antimicrobial compound, thus Adeps Bovis seu Bubali can
It can be a kind of potential non-drug growth promoter.Adeps Bovis seu Bubali herb contain volatile oil, mainly have to a P-cymene, carvacrol,
Thymol, Herba Pelargonii Graveolentis acetas etc. can diuresis, promote appetite, improve digestion, go expectorant, antibacterial effect, containing anti-ageing in every 1 milligram
Old element superoxide dismutase 187.80 microgram, is content soprano in vegetable, and its anti-oxidation function is very strong, eliminates certainly with it
For the antioxidant effect of base, exceed 42 times than Fructus Mali pumilae, exceed 30 times than Rhizoma Solani tuber osi, exceed 12 times than Fructus Citri tangerinae.Adeps Bovis seu Bubali acrid in the mouth,
Slightly warm in nature, has the effect of eliminating summer-heat from the exterior, inducing diuresis to remove edema.
Lycopene is containing 11 conjugated double bonds and the non-annularity plane of 2 non-conjugated double bonds in a kind of chemical structural formula
Polyunsaturated fat hydrocarbon, can form β mono-carotene through cyclisation.Lycopene is distributed in Fructus Lycopersici esculenti, Citrullus vulgaris, Fructus Cucurbitae moschatae, Lee, Fructus Kaki, recklessly
The fruits such as green pepper fruit, Fructus Persicae, Fructus Chaenomelis, Fructus Mangifera Indicae, Fructus psidii guajavae immaturus, Fructus Vitis viniferae, grapefruit, raspberry, molka, mandarin orange and Radix Raphani, Radix Dauci Sativae, turnip, sweet
The root of indigo plant etc., but content is considerably less, and be difficult to be absorbed.Human body self can not synthesize carotenoid, it is necessary to takes the photograph from meals
Take, eat the lycopene that a uncivilized nation eggplant can only absorb 0.05 milligram.Raw naturally occurring kind of biosynthesis pathway carotenoid
Lycopene is all alltrans, and steaming and decocting under high temperature to be passed through, the processing mode such as fried make lycopene by anti-configuration to cis
Transformation of configuration.Therefore the anti-ageing element of our Fructus Lycopersici esculenti must be extracted by high temperature steaming.
Adeps Bovis seu Bubali is the change aromatic plant that a kind of antioxidant is stronger, and herb defying age element superoxide dismutase is
18.78%.Such as Quercetin (Quercetin), compound 1, caffeic acid and protocatechuic acid etc., Quercetin and derivant thereof are plants
Boundary's distribution is the widest, have multiple bioactive pyrite compounds, and its existence form is glucosides or aglycon, tool hydrophilic and parent
Lipid, can remove PMA stimulates people's neutral white rill to produce AOR, and suppresses snperoxiaized release.Internal malonaldehyde can also be suppressed
(MDA) generation of class material, malonaldehyde cross-linked proteins and lipid can form senile pigment, here it is anti-aging effects it
One.Compound 1 and caffeinic non-oxidizability are suitable with BHA, and protocatechuic acid is a kind of high activity antioxidant.
Herb can extract aromatic oil, and Main Ingredients and Appearance is phenol type substances, and carvacrol accounts for 79.6%, and cymene accounts for 8.7%, Moschus moschiferous
Rhizoma et radix valerianae phenol accounts for 2.5%, terpinene 2.1%, wherein carvacrol and thymol, and thymol is proved the strongest antibacterial activity, its
Active ingredient has the strongest surface activity and fat-soluble (this characteristic can promote that the further of lycopene absorbs), can be fast
Speed penetrates sex pheromone cell membrane, thus results in etiology microorganism water unbalance and dead, and another carvacrol and thymol are at intestinal
The outer layer of tract epithelial cell is active, can accelerate the turnover rate of intestinal epithelial cell, reduces pathogen to intestinal epithelial cell
Infect, strengthen the abilities of digestive and absorption to nutrient substance, improve growth performance.
Under above-mentioned theory research and practical advice, the anti-ageing element of this Fructus Lycopersici esculenti can produce following meaning to human body:
1, prevent and suppress cancer: be on the one hand because its antioxidation；On the other hand it is that lycopene can block group
Knitting cell and gene mutation process occurs under the effect of extraneous mutagenic agent, this is one of important mechanisms of generating of tumor.Experiment is sent out
Existing, lycopene can affect mammary gland, lung and the S phase in uterine cancer cells cycle；Lycopene is by Gl in suppression cell cycle
Transformation stage to S affects the growth of cell；Lycopene is by suppressing the oxidation of LDL-C and grillING meat, fish
The formation of the heterocyclic amine produced in browning reaction, thus effectively suppress carcinogenic generation and induced tumor.Research shows,
Lycopene all has certain inhibitory action to digestive tract cancer, cervical cancer, breast carcinoma, skin carcinoma, bladder cancer etc..
2, protection cardiovascular and cerebrovascular vessel: lycopene is a kind of low cholesterol agent, and it can suppress macrophage 3-hydroxy-3-methyl
The auxiliary A of glutaryl, is the rate-limiting enzyme of a kind of Biosynthesis of cholesterol.Experiment finds, adds in the medium cultivating macrophage
After entering lycopene, its cholesterol biosynthesis reduces, and lycopene also increases macrophage low density lipoprotein, LDL (LDL) receptor simultaneously
Activity.In atherosclerotic generation and evolution, the lipoprotein oxidation in tunica intima is a key factor.Kind
Lycopene plays an important role in terms of reducing lipoprotein oxidation, slows down the development of cardiovascular disease.Adeps Bovis seu Bubali has blood pressure lowering
Effect, has the effect increasing coronary artery blood flow.
3, ultra-violet radiation resisting function: lycopene can be to ultraviolet injury resistant.Research worker gives 10 Healthy People β-recklessly
Individual with lycopene 1-2 month of Radix Raphani element, result takes the area minimizing of lycopene crowd's ultraviolet initiation erythema, and degree alleviates.
4, suppression mutagenesis: one of important mechanisms that tumor generates is that histiocyte issues in the effect of extraneous mutagenic agent
Raw gene mutation, and lycopene can block this process, plays antitumaous effect.As Mediterranean Region resident grillING fish and
Use tomato sauce while meat, decrease the formation of the mutagenic agenies such as miscellaneous amine in gastronomical process.So while local resident's eating is easy
Carcinogenic grillING food, but the sickness rate of cervical cancer, carcinoma of prostate and hepatocarcinoma is the lowest.
5, slow down aging, enhancing immunity: lycopene, Adeps Bovis seu Bubali extract can be with maximally effective antioxidants, can cancellation
Singlet oxygen and removing peroxylradicals, keep cell homergy, pre-anti-aging.Above-mentioned substance passes through digestive tract in vivo
Mucosa absorption enters blood and lymph, is distributed to testis, adrenal gland, prostate, pancreas, breast, ovary, liver, lung, colon, skin
Skin and various mucosal tissue, promote glandular secretion hormone, so that human body keeps vigorous energy；Remove these organs and group
Free radical in knitting, protects them from injury, enhancing human body immunity power.India scholar points out, lycopene can make sterile man
Sub-sperm quantity increases, vigor strengthens, thus cures sterile problem.
6, lycopene can be substantially improved skin allergy, eliminates the xerosis cutis and pruritus caused because of skin allergy
Sense, makes us feeling relaxed happy.
7, lycopene protection mucosa: lycopene is present in internal various mucous membrane tissue in a large number, and long-term taking can change
The kind various various discomforts caused because internal mucous membrane tissue destroys.As dry and astringent in dry cough, eyes, oral ulcer, protect gastrointestinal tract
Mucous membrane tissue etc..
8, lycopene also has extremely strong antialcoholism action.It is anti-that ethanol metabolic process in human body is mainly oxidoreduction
Should, substantial amounts of free radical can be produced.Take lycopene at ordinary times, capacity for liquor can be increased；Taking before drinking, dispelling effects of alcohol is notable,
The ethanol damage to liver can be alleviated；And take after drunk, the drunk symptoms such as headache, vomiting can be alleviated.
9, above-mentioned substance also has pre-preventing bone rarefaction, blood pressure lowering, alleviates the different physiological roles such as the asthma that causes of motion.
10, this product is to gastral effect: anti-corrosive antibacterial, and stomach invigorating is aid digestion, antiinflammatory, function of gallbladder promoting, prophylactic treatment constipation.
11, there is no any side effect, be especially suitable for long-term care and take.
Summary of the invention
The present invention seeks to for people provide one take instant, be prone to accept, be readily transported preservation, low price and
And the aroma type cattle Fructus Lycopersici esculenti electuary containing polyphenoils such as high concentration lycopene.
The present invention is achieved by the following technical solutions:
A kind of cattle Fructus Lycopersici esculenti electuary, it is characterised in that: described cattle Fructus Lycopersici esculenti electuary often bag formulation content is as follows:
Tomato solids thing 7g
Adeps Bovis seu Bubali extract 1.5g
Mel 1.5g.
Primary raw material is Fructus Lycopersici esculenti, the wild Adeps Bovis seu Bubali in Tianshan Mountains and the snow mountain mountain flower Mel that Xinjiang produces, by concentrating, extract, closing
One-tenth technology, organically by main component organic synthesis, changes Fructus Lycopersici esculenti traditional fresh (fresh), dry (Tomato Dry), beans (Fructus Lycopersici esculenti
Beans), dosage form and the eating method such as juice (Fructus Lycopersici esculenti juice), be allowed to conveniently to preserve, run off few (active substance), easily melt, good absorb, send out
Wave the defying age to human body, health-care effect.
The processing technique step of described cattle Fructus Lycopersici esculenti electuary is as follows:
1) tomato solids thing is prefabricated
Fructus Lycopersici esculenti is classified → and cleaning → finishing → burn → making beating → heating concentrates stand-by, it is ensured that its lycopene and include that dimension is raw
Element C is prevented from losing at interior multivitamin；
2) Adeps Bovis seu Bubali extract extraction
Efficient extraction process is used to extract yellow punt-pole phenol, P-p-Cymene, Moschus moschiferous hay-scented phenol, r-terpinene and the superoxides in Adeps Bovis seu Bubali
Dismutase, the content of superoxide dismutase is more than 18.78%；
3) raw material mixing
By the formula proportion mixing as described in claim 1 of tomato solids thing, Adeps Bovis seu Bubali extract and Mel；
4) bag distribution packaging
By prefabricated raw material by often bag tomato solids thing 7g, Adeps Bovis seu Bubali extract 1.5g and Mel 1.5g packaging.
The present invention has effect slow down aging, strengthens body immunity, low price, convenient transport preservation and taking convenience etc.
Feature.
Detailed description of the invention
Modern processing technique taked by this cattle Fructus Lycopersici esculenti electuary, by Fructus Lycopersici esculenti, the Xinjiang Wild Adeps Bovis seu Bubali of Xinjiang production, carries out clear respectively
Wash, repair, burn, pull an oar, heat concentration, extract, be dried, mix operations such as preparing, make electuary.Hobby according to people can
Make the finished products such as granule, powder, concentrated juice, bulk powder, class tea sample thing.
The present invention is the Fructus Lycopersici esculenti and the wild Adeps Bovis seu Bubali in Tianshan Mountains using Xinjiang to produce, and is characterized in that content of lycopene is high, its
In thickened solid composition, the content of lycopene is 0.5mg 1.5mg/g；Tianshan Mountains wild Adeps Bovis seu Bubali flowers, foliar SOD content equal
＞ 18.9%.Make the antioxidant of lycopene and Adeps Bovis seu Bubali in beverage and be significantly larger than commercially available capsule and other health promoting products.
Owing to Adeps Bovis seu Bubali is a kind of aromatic plant, the beverage course of processing of the present invention remains central volatile oil, makes
Its beverage can experience its peculiar delicate fragrance taste when drinking, and is not available for other any beverage.
Beverage adjuvant of the present invention with the addition of grassland, Tianshan Mountains Mel can accelerate beverage dissolving, increases beverage mouthfeel, strengthens again
Beverage health degree.
Beverage of the present invention is complete pure natural beverage, is not added with any preservative and chemical addition agent.Due to Adeps Bovis seu Bubali originally
It is a kind of natural antibacterial preservative substance, can replace chemical preservative, and there is no the teratogenesis of some chemical preservatives, carcinogenic, chronic
The side effect such as poisoning.It is beneficial to long period preservation.
Claims (2)
1. a cattle Fructus Lycopersici esculenti electuary, it is characterised in that: described cattle Fructus Lycopersici esculenti electuary often bag formulation content is as follows:
Tomato solids thing 7g
Adeps Bovis seu Bubali extract 1.5g
Mel 1.5g.
2. the processing technique of a cattle Fructus Lycopersici esculenti electuary according to claim 1, it is characterised in that: described cattle Fructus Lycopersici esculenti electuary
Processing technique step is as follows:
(1) tomato solids thing is prefabricated
Fructus Lycopersici esculenti is classified → and cleaning → finishing → burn → making beating → heating concentrates stand-by；
(2) Adeps Bovis seu Bubali extract extraction
Efficient extraction process is used to extract yellow punt-pole phenol, P-p-Cymene, Moschus moschiferous hay-scented phenol, r-terpinene and the superoxides in Adeps Bovis seu Bubali
Dismutase, the content of superoxide dismutase is more than 18.78%；
(3) raw material mixing
By the formula proportion mixing as described in claim 1 of tomato solids thing, Adeps Bovis seu Bubali extract and Mel；
(4) bag distribution packaging
By prefabricated raw material by often bag tomato solids thing 7g, Adeps Bovis seu Bubali extract 1.5g and Mel 1.5g packaging.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201610430675.9A CN106072113A (en) | 2016-06-17 | 2016-06-17 | Cattle Fructus Lycopersici esculenti electuary |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201610430675.9A CN106072113A (en) | 2016-06-17 | 2016-06-17 | Cattle Fructus Lycopersici esculenti electuary |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101115402A (en) * | 2004-12-16 | 2008-01-30 | 希尔氏宠物营养品公司 | Methods for enhancing the palatability of food compositions |
| CN103919067A (en) * | 2014-04-02 | 2014-07-16 | 浙江小二黑食品有限公司 | New method for preparing tomato powder |
| CN104305394A (en) * | 2014-10-09 | 2015-01-28 | 张璧云 | Instant drink comprising bubbles and dissolved gas and drink system |
| CN104883910A (en) * | 2012-11-27 | 2015-09-02 | 帝斯曼知识产权资产管理有限公司 | Process for the production of discrete solid extruded particles |
-
2016
- 2016-06-17 CN CN201610430675.9A patent/CN106072113A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101115402A (en) * | 2004-12-16 | 2008-01-30 | 希尔氏宠物营养品公司 | Methods for enhancing the palatability of food compositions |
| CN104883910A (en) * | 2012-11-27 | 2015-09-02 | 帝斯曼知识产权资产管理有限公司 | Process for the production of discrete solid extruded particles |
| CN103919067A (en) * | 2014-04-02 | 2014-07-16 | 浙江小二黑食品有限公司 | New method for preparing tomato powder |
| CN104305394A (en) * | 2014-10-09 | 2015-01-28 | 张璧云 | Instant drink comprising bubbles and dissolved gas and drink system |
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