CN106072113A - Cattle Fructus Lycopersici esculenti electuary - Google Patents
Cattle Fructus Lycopersici esculenti electuary Download PDFInfo
- Publication number
- CN106072113A CN106072113A CN201610430675.9A CN201610430675A CN106072113A CN 106072113 A CN106072113 A CN 106072113A CN 201610430675 A CN201610430675 A CN 201610430675A CN 106072113 A CN106072113 A CN 106072113A
- Authority
- CN
- China
- Prior art keywords
- lycopersici esculenti
- fructus lycopersici
- bovis seu
- seu bubali
- adeps bovis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 241000283690 Bos taurus Species 0.000 title claims abstract description 14
- 235000007688 Lycopersicon esculentum Nutrition 0.000 claims abstract description 11
- 239000007787 solid Substances 0.000 claims abstract description 9
- 239000002994 raw material Substances 0.000 claims abstract description 7
- 238000000034 method Methods 0.000 claims description 8
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims description 6
- 238000012545 processing Methods 0.000 claims description 6
- 102000019197 Superoxide Dismutase Human genes 0.000 claims description 4
- 108010012715 Superoxide dismutase Proteins 0.000 claims description 4
- 238000000605 extraction Methods 0.000 claims description 4
- 238000004806 packaging method and process Methods 0.000 claims description 4
- 244000153234 Hibiscus abelmoschus Species 0.000 claims description 3
- 238000009826 distribution Methods 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 3
- CHBNMKPHUSAEJE-KQLJZIGXSA-N 2,6,6-trimethyl-3-(2,6,6-trimethyl-3-bicyclo[3.1.1]hept-1-enyl)-3-[(3R)-2,6,6-trimethyl-3-bicyclo[3.1.1]hept-1-enyl]bicyclo[3.1.1]hept-1-ene Chemical compound C12=C([C@@H](CC(C1(C)C)C2)C1(C(=C2C(C(C1)C2)(C)C)C)C1C(=C2C(C(C1)C2)(C)C)C)C CHBNMKPHUSAEJE-KQLJZIGXSA-N 0.000 claims description 2
- OUUQCZGPVNCOIJ-UHFFFAOYSA-M Superoxide Chemical class [O-][O] OUUQCZGPVNCOIJ-UHFFFAOYSA-M 0.000 claims description 2
- 238000010009 beating Methods 0.000 claims description 2
- 238000004140 cleaning Methods 0.000 claims description 2
- 239000012141 concentrate Substances 0.000 claims description 2
- 238000009472 formulation Methods 0.000 claims description 2
- 238000010438 heat treatment Methods 0.000 claims description 2
- 241000227653 Lycopersicon Species 0.000 claims 4
- 235000013361 beverage Nutrition 0.000 abstract description 12
- 230000036541 health Effects 0.000 abstract description 8
- 240000003768 Solanum lycopersicum Species 0.000 abstract description 7
- 206010028980 Neoplasm Diseases 0.000 abstract description 6
- 230000015572 biosynthetic process Effects 0.000 abstract description 6
- 230000006870 function Effects 0.000 abstract description 5
- 230000036039 immunity Effects 0.000 abstract description 5
- 230000032683 aging Effects 0.000 abstract description 4
- 235000013305 food Nutrition 0.000 abstract description 4
- 238000004321 preservation Methods 0.000 abstract description 4
- 238000003786 synthesis reaction Methods 0.000 abstract description 4
- 201000011510 cancer Diseases 0.000 abstract description 3
- 230000002526 effect on cardiovascular system Effects 0.000 abstract description 3
- 239000008187 granular material Substances 0.000 abstract description 3
- 235000015097 nutrients Nutrition 0.000 abstract description 3
- 239000000843 powder Substances 0.000 abstract description 3
- 239000007788 liquid Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 208000017497 prostate disease Diseases 0.000 abstract 1
- 208000023958 prostate neoplasm Diseases 0.000 abstract 1
- 239000007909 solid dosage form Substances 0.000 abstract 1
- UPYKUZBSLRQECL-UKMVMLAPSA-N Lycopene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1C(=C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=C)CCCC2(C)C UPYKUZBSLRQECL-UKMVMLAPSA-N 0.000 description 34
- JEVVKJMRZMXFBT-XWDZUXABSA-N Lycophyll Natural products OC/C(=C/CC/C(=C\C=C\C(=C/C=C/C(=C\C=C\C=C(/C=C/C=C(\C=C\C=C(/CC/C=C(/CO)\C)\C)/C)\C)/C)\C)/C)/C JEVVKJMRZMXFBT-XWDZUXABSA-N 0.000 description 34
- 235000012661 lycopene Nutrition 0.000 description 34
- OAIJSZIZWZSQBC-GYZMGTAESA-N lycopene Chemical compound CC(C)=CCC\C(C)=C\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C=C(/C)CCC=C(C)C OAIJSZIZWZSQBC-GYZMGTAESA-N 0.000 description 34
- 239000001751 lycopene Substances 0.000 description 34
- 229960004999 lycopene Drugs 0.000 description 34
- ZCIHMQAPACOQHT-ZGMPDRQDSA-N trans-isorenieratene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/c1c(C)ccc(C)c1C)C=CC=C(/C)C=Cc2c(C)ccc(C)c2C ZCIHMQAPACOQHT-ZGMPDRQDSA-N 0.000 description 34
- 230000000694 effects Effects 0.000 description 16
- 239000000126 substance Substances 0.000 description 9
- MGSRCZKZVOBKFT-UHFFFAOYSA-N thymol Chemical compound CC(C)C1=CC=C(C)C=C1O MGSRCZKZVOBKFT-UHFFFAOYSA-N 0.000 description 8
- REFJWTPEDVJJIY-UHFFFAOYSA-N Quercetin Chemical compound C=1C(O)=CC(O)=C(C(C=2O)=O)C=1OC=2C1=CC=C(O)C(O)=C1 REFJWTPEDVJJIY-UHFFFAOYSA-N 0.000 description 6
- 239000003963 antioxidant agent Substances 0.000 description 6
- 230000003078 antioxidant effect Effects 0.000 description 6
- 235000006708 antioxidants Nutrition 0.000 description 6
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 6
- 241000196324 Embryophyta Species 0.000 description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 5
- 230000003712 anti-aging effect Effects 0.000 description 5
- YQUVCSBJEUQKSH-UHFFFAOYSA-N 3,4-dihydroxybenzoic acid Chemical compound OC(=O)C1=CC=C(O)C(O)=C1 YQUVCSBJEUQKSH-UHFFFAOYSA-N 0.000 description 4
- 239000005844 Thymol Substances 0.000 description 4
- 230000000844 anti-bacterial effect Effects 0.000 description 4
- RECUKUPTGUEGMW-UHFFFAOYSA-N carvacrol Chemical compound CC(C)C1=CC=C(C)C(O)=C1 RECUKUPTGUEGMW-UHFFFAOYSA-N 0.000 description 4
- HHTWOMMSBMNRKP-UHFFFAOYSA-N carvacrol Natural products CC(=C)C1=CC=C(C)C(O)=C1 HHTWOMMSBMNRKP-UHFFFAOYSA-N 0.000 description 4
- 235000007746 carvacrol Nutrition 0.000 description 4
- -1 compound 1 Chemical compound 0.000 description 4
- WYXXLXHHWYNKJF-UHFFFAOYSA-N isocarvacrol Natural products CC(C)C1=CC=C(O)C(C)=C1 WYXXLXHHWYNKJF-UHFFFAOYSA-N 0.000 description 4
- 210000004400 mucous membrane Anatomy 0.000 description 4
- 239000003755 preservative agent Substances 0.000 description 4
- 229960000790 thymol Drugs 0.000 description 4
- 108010007622 LDL Lipoproteins Proteins 0.000 description 3
- 102000007330 LDL Lipoproteins Human genes 0.000 description 3
- WSMYVTOQOOLQHP-UHFFFAOYSA-N Malondialdehyde Chemical compound O=CCC=O WSMYVTOQOOLQHP-UHFFFAOYSA-N 0.000 description 3
- ZVOLCUVKHLEPEV-UHFFFAOYSA-N Quercetagetin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=C(O)C(O)=C(O)C=C2O1 ZVOLCUVKHLEPEV-UHFFFAOYSA-N 0.000 description 3
- HWTZYBCRDDUBJY-UHFFFAOYSA-N Rhynchosin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=CC(O)=C(O)C=C2O1 HWTZYBCRDDUBJY-UHFFFAOYSA-N 0.000 description 3
- 230000003064 anti-oxidating effect Effects 0.000 description 3
- 230000000711 cancerogenic effect Effects 0.000 description 3
- 231100000315 carcinogenic Toxicity 0.000 description 3
- 235000021466 carotenoid Nutrition 0.000 description 3
- 150000001747 carotenoids Chemical class 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 3
- 235000012000 cholesterol Nutrition 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 230000035622 drinking Effects 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 3
- 210000001035 gastrointestinal tract Anatomy 0.000 description 3
- MWDZOUNAPSSOEL-UHFFFAOYSA-N kaempferol Natural products OC1=C(C(=O)c2cc(O)cc(O)c2O1)c3ccc(O)cc3 MWDZOUNAPSSOEL-UHFFFAOYSA-N 0.000 description 3
- 210000002540 macrophage Anatomy 0.000 description 3
- 230000003647 oxidation Effects 0.000 description 3
- 238000007254 oxidation reaction Methods 0.000 description 3
- 230000002335 preservative effect Effects 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 235000005875 quercetin Nutrition 0.000 description 3
- 229960001285 quercetin Drugs 0.000 description 3
- 150000003254 radicals Chemical class 0.000 description 3
- 238000011160 research Methods 0.000 description 3
- 241000251468 Actinopterygii Species 0.000 description 2
- 206010006187 Breast cancer Diseases 0.000 description 2
- 208000026310 Breast neoplasm Diseases 0.000 description 2
- 206010008342 Cervix carcinoma Diseases 0.000 description 2
- 201000004624 Dermatitis Diseases 0.000 description 2
- 206010064571 Gene mutation Diseases 0.000 description 2
- 108090001030 Lipoproteins Proteins 0.000 description 2
- 102000004895 Lipoproteins Human genes 0.000 description 2
- 244000046052 Phaseolus vulgaris Species 0.000 description 2
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 2
- 208000004880 Polyuria Diseases 0.000 description 2
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- OENHQHLEOONYIE-UKMVMLAPSA-N all-trans beta-carotene Natural products CC=1CCCC(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C OENHQHLEOONYIE-UKMVMLAPSA-N 0.000 description 2
- 125000003118 aryl group Chemical group 0.000 description 2
- 235000013734 beta-carotene Nutrition 0.000 description 2
- 239000011648 beta-carotene Substances 0.000 description 2
- TUPZEYHYWIEDIH-WAIFQNFQSA-N beta-carotene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2=CCCCC2(C)C TUPZEYHYWIEDIH-WAIFQNFQSA-N 0.000 description 2
- 229960002747 betacarotene Drugs 0.000 description 2
- 201000008275 breast carcinoma Diseases 0.000 description 2
- 201000010881 cervical cancer Diseases 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 229940125904 compound 1 Drugs 0.000 description 2
- 230000029087 digestion Effects 0.000 description 2
- 230000035619 diuresis Effects 0.000 description 2
- 235000013399 edible fruits Nutrition 0.000 description 2
- 230000002708 enhancing effect Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 239000007952 growth promoter Substances 0.000 description 2
- 230000001965 increasing effect Effects 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- 210000002490 intestinal epithelial cell Anatomy 0.000 description 2
- 238000009940 knitting Methods 0.000 description 2
- 150000002632 lipids Chemical class 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 235000013372 meat Nutrition 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 210000004877 mucosa Anatomy 0.000 description 2
- 239000003471 mutagenic agent Substances 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 201000001514 prostate carcinoma Diseases 0.000 description 2
- 238000010025 steaming Methods 0.000 description 2
- 230000001629 suppression Effects 0.000 description 2
- QAIPRVGONGVQAS-DUXPYHPUSA-N trans-caffeic acid Chemical compound OC(=O)\C=C\C1=CC=C(O)C(O)=C1 QAIPRVGONGVQAS-DUXPYHPUSA-N 0.000 description 2
- 230000009466 transformation Effects 0.000 description 2
- 239000000341 volatile oil Substances 0.000 description 2
- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 description 2
- ACEAELOMUCBPJP-UHFFFAOYSA-N (E)-3,4,5-trihydroxycinnamic acid Natural products OC(=O)C=CC1=CC(O)=C(O)C(O)=C1 ACEAELOMUCBPJP-UHFFFAOYSA-N 0.000 description 1
- 241000722824 Ardisia crenata Species 0.000 description 1
- 206010005003 Bladder cancer Diseases 0.000 description 1
- 240000002791 Brassica napus Species 0.000 description 1
- 235000011293 Brassica napus Nutrition 0.000 description 1
- 235000000540 Brassica rapa subsp rapa Nutrition 0.000 description 1
- 235000008534 Capsicum annuum var annuum Nutrition 0.000 description 1
- 240000008384 Capsicum annuum var. annuum Species 0.000 description 1
- 239000004215 Carbon black (E152) Substances 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 241000033870 Citrullus lanatus subsp. vulgaris Species 0.000 description 1
- 235000012840 Citrullus vulgaris Nutrition 0.000 description 1
- 241001672694 Citrus reticulata Species 0.000 description 1
- 240000000560 Citrus x paradisi Species 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 1
- 206010013082 Discomfort Diseases 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 206010015150 Erythema Diseases 0.000 description 1
- 206010016352 Feeling of relaxation Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 244000283207 Indigofera tinctoria Species 0.000 description 1
- 108010028554 LDL Cholesterol Proteins 0.000 description 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 description 1
- 241001093152 Mangifera Species 0.000 description 1
- 241001597008 Nomeidae Species 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 208000007117 Oral Ulcer Diseases 0.000 description 1
- 241001529744 Origanum Species 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 235000011034 Rubus glaucus Nutrition 0.000 description 1
- 244000235659 Rubus idaeus Species 0.000 description 1
- 235000009122 Rubus idaeus Nutrition 0.000 description 1
- 230000018199 S phase Effects 0.000 description 1
- 239000000877 Sex Attractant Substances 0.000 description 1
- 244000061458 Solanum melongena Species 0.000 description 1
- 235000002597 Solanum melongena Nutrition 0.000 description 1
- 208000031320 Teratogenesis Diseases 0.000 description 1
- 244000269722 Thea sinensis Species 0.000 description 1
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 description 1
- 208000002495 Uterine Neoplasms Diseases 0.000 description 1
- 235000009392 Vitis Nutrition 0.000 description 1
- 241000219095 Vitis Species 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 206010048222 Xerosis Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 210000004100 adrenal gland Anatomy 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 239000004599 antimicrobial Substances 0.000 description 1
- 208000002399 aphthous stomatitis Diseases 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 239000010692 aromatic oil Substances 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 230000003143 atherosclerotic effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000975 bioactive effect Effects 0.000 description 1
- 230000006696 biosynthetic metabolic pathway Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 230000004531 blood pressure lowering effect Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 229940074360 caffeic acid Drugs 0.000 description 1
- 235000004883 caffeic acid Nutrition 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 230000022131 cell cycle Effects 0.000 description 1
- 230000010261 cell growth Effects 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- QAIPRVGONGVQAS-UHFFFAOYSA-N cis-caffeic acid Natural products OC(=O)C=CC1=CC=C(O)C(O)=C1 QAIPRVGONGVQAS-UHFFFAOYSA-N 0.000 description 1
- 210000001072 colon Anatomy 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 210000004351 coronary vessel Anatomy 0.000 description 1
- 229930007927 cymene Natural products 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 208000017574 dry cough Diseases 0.000 description 1
- 210000002919 epithelial cell Anatomy 0.000 description 1
- 231100000321 erythema Toxicity 0.000 description 1
- 239000003172 expectorant agent Substances 0.000 description 1
- 230000003419 expectorant effect Effects 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 230000000762 glandular Effects 0.000 description 1
- 229930182478 glucoside Natural products 0.000 description 1
- 150000008131 glucosides Chemical group 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 210000003701 histiocyte Anatomy 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- 150000002430 hydrocarbons Chemical class 0.000 description 1
- 230000001976 improved effect Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 210000002751 lymph Anatomy 0.000 description 1
- 239000002075 main ingredient Substances 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 210000005075 mammary gland Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 231100000350 mutagenesis Toxicity 0.000 description 1
- 238000002703 mutagenesis Methods 0.000 description 1
- 231100000219 mutagenic Toxicity 0.000 description 1
- 230000003505 mutagenic effect Effects 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 210000001672 ovary Anatomy 0.000 description 1
- HFPZCAJZSCWRBC-UHFFFAOYSA-N p-cymene Chemical compound CC(C)C1=CC=C(C)C=C1 HFPZCAJZSCWRBC-UHFFFAOYSA-N 0.000 description 1
- 210000000496 pancreas Anatomy 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 235000021085 polyunsaturated fats Nutrition 0.000 description 1
- 238000011321 prophylaxis Methods 0.000 description 1
- 210000002307 prostate Anatomy 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- NIFIFKQPDTWWGU-UHFFFAOYSA-N pyrite Chemical class [Fe+2].[S-][S-] NIFIFKQPDTWWGU-UHFFFAOYSA-N 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 235000015067 sauces Nutrition 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 210000003491 skin Anatomy 0.000 description 1
- 201000000849 skin cancer Diseases 0.000 description 1
- 201000008261 skin carcinoma Diseases 0.000 description 1
- 239000008247 solid mixture Substances 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- DKVBOUDTNWVDEP-NJCHZNEYSA-N teicoplanin aglycone Chemical compound N([C@H](C(N[C@@H](C1=CC(O)=CC(O)=C1C=1C(O)=CC=C2C=1)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)OC=1C=C3C=C(C=1O)OC1=CC=C(C=C1Cl)C[C@H](C(=O)N1)NC([C@H](N)C=4C=C(O5)C(O)=CC=4)=O)C(=O)[C@@H]2NC(=O)[C@@H]3NC(=O)[C@@H]1C1=CC5=CC(O)=C1 DKVBOUDTNWVDEP-NJCHZNEYSA-N 0.000 description 1
- 229930006978 terpinene Natural products 0.000 description 1
- 150000003507 terpinene derivatives Chemical class 0.000 description 1
- 210000001550 testis Anatomy 0.000 description 1
- 230000032258 transport Effects 0.000 description 1
- 210000004026 tunica intima Anatomy 0.000 description 1
- 230000007306 turnover Effects 0.000 description 1
- 201000005112 urinary bladder cancer Diseases 0.000 description 1
- 206010046766 uterine cancer Diseases 0.000 description 1
- 208000012991 uterine carcinoma Diseases 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of of health nutrient field and apply natural food Fructus Lycopersici esculenti, Adeps Bovis seu Bubali, a kind of cattle Fructus Lycopersici esculenti electuary with certain health care functions of Mel synthesis.The Fructus Lycopersici esculenti, the wild Adeps Bovis seu Bubali in Tianshan Mountains and the snow mountain mountain flower Mel that use Xinjiang to produce are raw material, by concentrating, extracting and synthetic technology, the granules beverage organically made by main component organic synthesis, the most often include tomato solids thing 7g, Adeps Bovis seu Bubali extract 1.5g, Mel 1.5g.The present invention is concentrated liquid, dissolved granule, powder or blocks of solid dosage form, provides a kind of low price, convenient transport preservation, taking convenience and crowd to be prone to the beverage accepted for people.Can effectively slow down aging, strengthen body immunity, prevent and suppress cancer, protect cardiovascular and cerebrovascular vessel, prevention and control human prostate's disease and tumor.Improve human body total quality, increase human longevity expected value.
Description
Technical field
The present invention relates to a kind of drinking food product in health nutrient field, be related specifically to apply natural food Fructus Lycopersici esculenti, cattle
Extremely, a kind of cattle Fructus Lycopersici esculenti electuary with certain health care functions of Mel synthesis.
Background technology
Lycopene (Lycopene) is the one of carotenoid, is the strongest a kind of antioxidant, has extremely strong clear
Except the ability of free radical, there is remarkable result to preventing and treating carcinoma of prostate, pulmonary carcinoma, breast carcinoma, uterus carcinoma etc., also prevent cardiovascular and cerebrovascular vessel
Disease, raising effect such as immunity, slow down aging, have the title of plant gold, be described as " new lovers of 21 century health product ".It is
Antioxidant the strongest in nature, its antioxidation is 2 times of beta-carotene, 100 times of VE.Removing human body, " ten thousand is sick
Source "---free radical aspect, the effect of lycopene is more powerful than beta-carotene.
Adeps Bovis seu Bubali is Labiatae Origanum herbaceos perennial, for armaticity spice berry.All have in worldwide with
This is human drugs and the health product of raw material, is a kind of potential natural antibiotics and non-drug growth promoter.American agriculture
The background information of " phytochemistry and the plant species " in portion shows, Adeps Bovis seu Bubali contains more than 30 kind of antimicrobial compound, thus Adeps Bovis seu Bubali can
It can be a kind of potential non-drug growth promoter.Adeps Bovis seu Bubali herb contain volatile oil, mainly have to a P-cymene, carvacrol,
Thymol, Herba Pelargonii Graveolentis acetas etc. can diuresis, promote appetite, improve digestion, go expectorant, antibacterial effect, containing anti-ageing in every 1 milligram
Old element superoxide dismutase 187.80 microgram, is content soprano in vegetable, and its anti-oxidation function is very strong, eliminates certainly with it
For the antioxidant effect of base, exceed 42 times than Fructus Mali pumilae, exceed 30 times than Rhizoma Solani tuber osi, exceed 12 times than Fructus Citri tangerinae.Adeps Bovis seu Bubali acrid in the mouth,
Slightly warm in nature, has the effect of eliminating summer-heat from the exterior, inducing diuresis to remove edema.
Lycopene is containing 11 conjugated double bonds and the non-annularity plane of 2 non-conjugated double bonds in a kind of chemical structural formula
Polyunsaturated fat hydrocarbon, can form β mono-carotene through cyclisation.Lycopene is distributed in Fructus Lycopersici esculenti, Citrullus vulgaris, Fructus Cucurbitae moschatae, Lee, Fructus Kaki, recklessly
The fruits such as green pepper fruit, Fructus Persicae, Fructus Chaenomelis, Fructus Mangifera Indicae, Fructus psidii guajavae immaturus, Fructus Vitis viniferae, grapefruit, raspberry, molka, mandarin orange and Radix Raphani, Radix Dauci Sativae, turnip, sweet
The root of indigo plant etc., but content is considerably less, and be difficult to be absorbed.Human body self can not synthesize carotenoid, it is necessary to takes the photograph from meals
Take, eat the lycopene that a uncivilized nation eggplant can only absorb 0.05 milligram.Raw naturally occurring kind of biosynthesis pathway carotenoid
Lycopene is all alltrans, and steaming and decocting under high temperature to be passed through, the processing mode such as fried make lycopene by anti-configuration to cis
Transformation of configuration.Therefore the anti-ageing element of our Fructus Lycopersici esculenti must be extracted by high temperature steaming.
Adeps Bovis seu Bubali is the change aromatic plant that a kind of antioxidant is stronger, and herb defying age element superoxide dismutase is
18.78%.Such as Quercetin (Quercetin), compound 1, caffeic acid and protocatechuic acid etc., Quercetin and derivant thereof are plants
Boundary's distribution is the widest, have multiple bioactive pyrite compounds, and its existence form is glucosides or aglycon, tool hydrophilic and parent
Lipid, can remove PMA stimulates people's neutral white rill to produce AOR, and suppresses snperoxiaized release.Internal malonaldehyde can also be suppressed
(MDA) generation of class material, malonaldehyde cross-linked proteins and lipid can form senile pigment, here it is anti-aging effects it
One.Compound 1 and caffeinic non-oxidizability are suitable with BHA, and protocatechuic acid is a kind of high activity antioxidant.
Herb can extract aromatic oil, and Main Ingredients and Appearance is phenol type substances, and carvacrol accounts for 79.6%, and cymene accounts for 8.7%, Moschus moschiferous
Rhizoma et radix valerianae phenol accounts for 2.5%, terpinene 2.1%, wherein carvacrol and thymol, and thymol is proved the strongest antibacterial activity, its
Active ingredient has the strongest surface activity and fat-soluble (this characteristic can promote that the further of lycopene absorbs), can be fast
Speed penetrates sex pheromone cell membrane, thus results in etiology microorganism water unbalance and dead, and another carvacrol and thymol are at intestinal
The outer layer of tract epithelial cell is active, can accelerate the turnover rate of intestinal epithelial cell, reduces pathogen to intestinal epithelial cell
Infect, strengthen the abilities of digestive and absorption to nutrient substance, improve growth performance.
Under above-mentioned theory research and practical advice, the anti-ageing element of this Fructus Lycopersici esculenti can produce following meaning to human body:
1, prevent and suppress cancer: be on the one hand because its antioxidation；On the other hand it is that lycopene can block group
Knitting cell and gene mutation process occurs under the effect of extraneous mutagenic agent, this is one of important mechanisms of generating of tumor.Experiment is sent out
Existing, lycopene can affect mammary gland, lung and the S phase in uterine cancer cells cycle；Lycopene is by Gl in suppression cell cycle
Transformation stage to S affects the growth of cell；Lycopene is by suppressing the oxidation of LDL-C and grillING meat, fish
The formation of the heterocyclic amine produced in browning reaction, thus effectively suppress carcinogenic generation and induced tumor.Research shows,
Lycopene all has certain inhibitory action to digestive tract cancer, cervical cancer, breast carcinoma, skin carcinoma, bladder cancer etc..
2, protection cardiovascular and cerebrovascular vessel: lycopene is a kind of low cholesterol agent, and it can suppress macrophage 3-hydroxy-3-methyl
The auxiliary A of glutaryl, is the rate-limiting enzyme of a kind of Biosynthesis of cholesterol.Experiment finds, adds in the medium cultivating macrophage
After entering lycopene, its cholesterol biosynthesis reduces, and lycopene also increases macrophage low density lipoprotein, LDL (LDL) receptor simultaneously
Activity.In atherosclerotic generation and evolution, the lipoprotein oxidation in tunica intima is a key factor.Kind
Lycopene plays an important role in terms of reducing lipoprotein oxidation, slows down the development of cardiovascular disease.Adeps Bovis seu Bubali has blood pressure lowering
Effect, has the effect increasing coronary artery blood flow.
3, ultra-violet radiation resisting function: lycopene can be to ultraviolet injury resistant.Research worker gives 10 Healthy People β-recklessly
Individual with lycopene 1-2 month of Radix Raphani element, result takes the area minimizing of lycopene crowd's ultraviolet initiation erythema, and degree alleviates.
4, suppression mutagenesis: one of important mechanisms that tumor generates is that histiocyte issues in the effect of extraneous mutagenic agent
Raw gene mutation, and lycopene can block this process, plays antitumaous effect.As Mediterranean Region resident grillING fish and
Use tomato sauce while meat, decrease the formation of the mutagenic agenies such as miscellaneous amine in gastronomical process.So while local resident's eating is easy
Carcinogenic grillING food, but the sickness rate of cervical cancer, carcinoma of prostate and hepatocarcinoma is the lowest.
5, slow down aging, enhancing immunity: lycopene, Adeps Bovis seu Bubali extract can be with maximally effective antioxidants, can cancellation
Singlet oxygen and removing peroxylradicals, keep cell homergy, pre-anti-aging.Above-mentioned substance passes through digestive tract in vivo
Mucosa absorption enters blood and lymph, is distributed to testis, adrenal gland, prostate, pancreas, breast, ovary, liver, lung, colon, skin
Skin and various mucosal tissue, promote glandular secretion hormone, so that human body keeps vigorous energy；Remove these organs and group
Free radical in knitting, protects them from injury, enhancing human body immunity power.India scholar points out, lycopene can make sterile man
Sub-sperm quantity increases, vigor strengthens, thus cures sterile problem.
6, lycopene can be substantially improved skin allergy, eliminates the xerosis cutis and pruritus caused because of skin allergy
Sense, makes us feeling relaxed happy.
7, lycopene protection mucosa: lycopene is present in internal various mucous membrane tissue in a large number, and long-term taking can change
The kind various various discomforts caused because internal mucous membrane tissue destroys.As dry and astringent in dry cough, eyes, oral ulcer, protect gastrointestinal tract
Mucous membrane tissue etc..
8, lycopene also has extremely strong antialcoholism action.It is anti-that ethanol metabolic process in human body is mainly oxidoreduction
Should, substantial amounts of free radical can be produced.Take lycopene at ordinary times, capacity for liquor can be increased；Taking before drinking, dispelling effects of alcohol is notable,
The ethanol damage to liver can be alleviated；And take after drunk, the drunk symptoms such as headache, vomiting can be alleviated.
9, above-mentioned substance also has pre-preventing bone rarefaction, blood pressure lowering, alleviates the different physiological roles such as the asthma that causes of motion.
10, this product is to gastral effect: anti-corrosive antibacterial, and stomach invigorating is aid digestion, antiinflammatory, function of gallbladder promoting, prophylactic treatment constipation.
11, there is no any side effect, be especially suitable for long-term care and take.
Summary of the invention
The present invention seeks to for people provide one take instant, be prone to accept, be readily transported preservation, low price and
And the aroma type cattle Fructus Lycopersici esculenti electuary containing polyphenoils such as high concentration lycopene.
The present invention is achieved by the following technical solutions:
A kind of cattle Fructus Lycopersici esculenti electuary, it is characterised in that: described cattle Fructus Lycopersici esculenti electuary often bag formulation content is as follows:
Tomato solids thing 7g
Adeps Bovis seu Bubali extract 1.5g
Mel 1.5g.
Primary raw material is Fructus Lycopersici esculenti, the wild Adeps Bovis seu Bubali in Tianshan Mountains and the snow mountain mountain flower Mel that Xinjiang produces, by concentrating, extract, closing
One-tenth technology, organically by main component organic synthesis, changes Fructus Lycopersici esculenti traditional fresh (fresh), dry (Tomato Dry), beans (Fructus Lycopersici esculenti
Beans), dosage form and the eating method such as juice (Fructus Lycopersici esculenti juice), be allowed to conveniently to preserve, run off few (active substance), easily melt, good absorb, send out
Wave the defying age to human body, health-care effect.
The processing technique step of described cattle Fructus Lycopersici esculenti electuary is as follows:
1) tomato solids thing is prefabricated
Fructus Lycopersici esculenti is classified → and cleaning → finishing → burn → making beating → heating concentrates stand-by, it is ensured that its lycopene and include that dimension is raw
Element C is prevented from losing at interior multivitamin；
2) Adeps Bovis seu Bubali extract extraction
Efficient extraction process is used to extract yellow punt-pole phenol, P-p-Cymene, Moschus moschiferous hay-scented phenol, r-terpinene and the superoxides in Adeps Bovis seu Bubali
Dismutase, the content of superoxide dismutase is more than 18.78%；
3) raw material mixing
By the formula proportion mixing as described in claim 1 of tomato solids thing, Adeps Bovis seu Bubali extract and Mel；
4) bag distribution packaging
By prefabricated raw material by often bag tomato solids thing 7g, Adeps Bovis seu Bubali extract 1.5g and Mel 1.5g packaging.
The present invention has effect slow down aging, strengthens body immunity, low price, convenient transport preservation and taking convenience etc.
Feature.
Detailed description of the invention
Modern processing technique taked by this cattle Fructus Lycopersici esculenti electuary, by Fructus Lycopersici esculenti, the Xinjiang Wild Adeps Bovis seu Bubali of Xinjiang production, carries out clear respectively
Wash, repair, burn, pull an oar, heat concentration, extract, be dried, mix operations such as preparing, make electuary.Hobby according to people can
Make the finished products such as granule, powder, concentrated juice, bulk powder, class tea sample thing.
The present invention is the Fructus Lycopersici esculenti and the wild Adeps Bovis seu Bubali in Tianshan Mountains using Xinjiang to produce, and is characterized in that content of lycopene is high, its
In thickened solid composition, the content of lycopene is 0.5mg 1.5mg/g；Tianshan Mountains wild Adeps Bovis seu Bubali flowers, foliar SOD content equal
＞ 18.9%.Make the antioxidant of lycopene and Adeps Bovis seu Bubali in beverage and be significantly larger than commercially available capsule and other health promoting products.
Owing to Adeps Bovis seu Bubali is a kind of aromatic plant, the beverage course of processing of the present invention remains central volatile oil, makes
Its beverage can experience its peculiar delicate fragrance taste when drinking, and is not available for other any beverage.
Beverage adjuvant of the present invention with the addition of grassland, Tianshan Mountains Mel can accelerate beverage dissolving, increases beverage mouthfeel, strengthens again
Beverage health degree.
Beverage of the present invention is complete pure natural beverage, is not added with any preservative and chemical addition agent.Due to Adeps Bovis seu Bubali originally
It is a kind of natural antibacterial preservative substance, can replace chemical preservative, and there is no the teratogenesis of some chemical preservatives, carcinogenic, chronic
The side effect such as poisoning.It is beneficial to long period preservation.
Claims (2)
1. a cattle Fructus Lycopersici esculenti electuary, it is characterised in that: described cattle Fructus Lycopersici esculenti electuary often bag formulation content is as follows:
Tomato solids thing 7g
Adeps Bovis seu Bubali extract 1.5g
Mel 1.5g.
2. the processing technique of a cattle Fructus Lycopersici esculenti electuary according to claim 1, it is characterised in that: described cattle Fructus Lycopersici esculenti electuary
Processing technique step is as follows:
(1) tomato solids thing is prefabricated
Fructus Lycopersici esculenti is classified → and cleaning → finishing → burn → making beating → heating concentrates stand-by；
(2) Adeps Bovis seu Bubali extract extraction
Efficient extraction process is used to extract yellow punt-pole phenol, P-p-Cymene, Moschus moschiferous hay-scented phenol, r-terpinene and the superoxides in Adeps Bovis seu Bubali
Dismutase, the content of superoxide dismutase is more than 18.78%；
(3) raw material mixing
By the formula proportion mixing as described in claim 1 of tomato solids thing, Adeps Bovis seu Bubali extract and Mel；
(4) bag distribution packaging
By prefabricated raw material by often bag tomato solids thing 7g, Adeps Bovis seu Bubali extract 1.5g and Mel 1.5g packaging.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610430675.9A CN106072113A (en) | 2016-06-17 | 2016-06-17 | Cattle Fructus Lycopersici esculenti electuary |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610430675.9A CN106072113A (en) | 2016-06-17 | 2016-06-17 | Cattle Fructus Lycopersici esculenti electuary |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106072113A true CN106072113A (en) | 2016-11-09 |
Family
ID=57235610
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610430675.9A Pending CN106072113A (en) | 2016-06-17 | 2016-06-17 | Cattle Fructus Lycopersici esculenti electuary |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106072113A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101115402A (en) * | 2004-12-16 | 2008-01-30 | 希尔氏宠物营养品公司 | Methods for enhancing the palatability of food compositions |
| CN103919067A (en) * | 2014-04-02 | 2014-07-16 | 浙江小二黑食品有限公司 | New method for preparing tomato powder |
| CN104305394A (en) * | 2014-10-09 | 2015-01-28 | 张璧云 | Instant drink comprising bubbles and dissolved gas and drink system |
| CN104883910A (en) * | 2012-11-27 | 2015-09-02 | 帝斯曼知识产权资产管理有限公司 | Process for the production of discrete solid extruded particles |
-
2016
- 2016-06-17 CN CN201610430675.9A patent/CN106072113A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101115402A (en) * | 2004-12-16 | 2008-01-30 | 希尔氏宠物营养品公司 | Methods for enhancing the palatability of food compositions |
| CN104883910A (en) * | 2012-11-27 | 2015-09-02 | 帝斯曼知识产权资产管理有限公司 | Process for the production of discrete solid extruded particles |
| CN103919067A (en) * | 2014-04-02 | 2014-07-16 | 浙江小二黑食品有限公司 | New method for preparing tomato powder |
| CN104305394A (en) * | 2014-10-09 | 2015-01-28 | 张璧云 | Instant drink comprising bubbles and dissolved gas and drink system |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR20140049673A (en) | Manufacturing method of the enzyme using 125 kinds of medicinal herb extracts (extract using extract by the co2 (or n2) carrier gas method, enzyme extract by the fermentation method, microwave and filter) | |
| CN103027142B (en) | Skimmia japonica scented tea and making technology | |
| Tarantul et al. | Onion (lat. Állium cépa) | |
| KR20200106577A (en) | Composition for anti-oxidant, anti-inflammatory and relieving swelling containing plant complex extracts | |
| CN103859276B (en) | Health porridge for maintaining beauty and keeping young and preparation method of health porridge | |
| KR20220059078A (en) | A functional food additive | |
| CN104068177A (en) | Health-care life-lengthening natural plant tea | |
| CN104026506A (en) | Health care water chestnut flour and preparation method thereof | |
| CN106387163A (en) | Camellia oleifera having effects of assisting in reducing blood sugar, reducing blood lipid and resisting oxidation and preparation method of camellia oleifera | |
| KR102491108B1 (en) | Manufacturing process for rice syrup by using red ginseng and red ginseng rice syrup thereby the same that | |
| KR101037572B1 (en) | Powder manufacturing process using rind and pip of rubus coreanus | |
| CN107624912A (en) | Flowers Pu'er cooked tea food and its preparation method and application | |
| KR20090057342A (en) | Sweetish loess the amenity traditional soy sauce | |
| CN106072113A (en) | Cattle Fructus Lycopersici esculenti electuary | |
| KR101524128B1 (en) | A dietary supplement | |
| KR101152272B1 (en) | Composition of Food for relief of alcoholic hangover and preparation method thereof | |
| CN105942115A (en) | Aloe and wax gourd fermented drink and preparation method thereof | |
| CN104872322A (en) | Snake gourd fruit and tartary buckwheat tea and method for manufacturing same | |
| KR20100118223A (en) | A granule of chinese cabbage | |
| CN104106803A (en) | Buckwheat jam tea paste and preparation method thereof | |
| Selvamuthukumaran | Amla (Indian Gooseberry): Characteristics, Therapeutic Potential, and Its Value Addition | |
| KR101348312B1 (en) | Fermented extract of onion and manufacturing process of the same | |
| KR102683022B1 (en) | METHOD FOR MANUFACTURING SEASONING SAUCE FOR PORK USING Flammulina velutipes EXTRACT AND SEASONING SAUCE FOR PORK PRODUCED THEREBY | |
| KR102515041B1 (en) | Health food using sprout ginseng and manufacturing method of the same | |
| KR20090057345A (en) | Tradition the main family korean hot pepper paste |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20161109 |
|
| RJ01 | Rejection of invention patent application after publication |