CN106053587A - Spatial discrimination spectrum acquisition equipment, fluorography equipment and ion mobility spectrometer - Google Patents
Spatial discrimination spectrum acquisition equipment, fluorography equipment and ion mobility spectrometer Download PDFInfo
- Publication number
- CN106053587A CN106053587A CN201610343841.1A CN201610343841A CN106053587A CN 106053587 A CN106053587 A CN 106053587A CN 201610343841 A CN201610343841 A CN 201610343841A CN 106053587 A CN106053587 A CN 106053587A
- Authority
- CN
- China
- Prior art keywords
- spatial discrimination
- ion
- fluorescent samples
- collection
- reception plate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
- G01N27/622—Ion mobility spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/06—Illumination; Optics
- G01N2201/061—Sources
- G01N2201/06113—Coherent sources; lasers
Landscapes
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Abstract
The invention discloses spatial discrimination spectrum acquisition equipment for an ion mobility spectrometer. The spatial discrimination spectrum acquisition equipment comprises an ionization source for generating fluorescent sample ions, a migration tube for separating sample ions, and a receiving plate, which is arranged on the output port of the migration tube. During the process that the receiving plate receives fluorescent sample ions, the receiving plate moves relatively to the output port of the migration tube, so that different areas of the surface of the receiving plate can sequentially capture fluorescent sample ions that reach the receiving plate in a migration rate sequence; wherein the speed of relative moving is greater than or equal to the moving speed of fluorescent sample ions so that fluorescent sample ions on the receiving plate can be bombarded. The invention also discloses fluorography equipment that is cooperatively used with the spatial discrimination spectrum acquisition equipment, and an ion mobility spectrometer comprising the spatial discrimination spectrum acquisition equipment and fluorography equipment. The conventional detection mode of ion mobility spectrometer is changed so as to improve the detection capability of ion mobility spectrometry.
Description
Technical field
The present invention relates to ionic migration spectrometer, particularly relate to a kind of spatial discrimination collection of illustrative plates collection for ionic migration spectrometer
Equipment, fluorography equipment and there is the ionic migration spectrometer of the said equipment.
Background technology
The usual structure of fluorescence molecule headed by biomacromolecule albumen is complex and has corresponding with steric configuration
Biological nature, ionic migration spectrometer can be carried out structural analysis by special resolved way (mobility) to this quasi-molecule and grind
Study carefully.Especially to the fluorescence molecule that some mass-to-charge ratioes are close or arrangement same space configuration difference is bigger.
At present, the detection of sample ions mobility generally utilizes the ion current two-dimensional curve to drift time on detector
Obtain its time step portion and distinguish spectrogram.Time step should be readily appreciated that as the ratio of ion migration spectrogram is countershaft and operate.Analyze not
During with sample, owing to the sample after being ionized has specific migration rate, so moving under electric field with air-flow dual function
Can spatial arrangements distribution sequentially in moving pipe.The arrival corresponding with its migration rate is shown through identical migration distance
Time, thus the time step obtaining correspondence differentiates spectrogram, user is generally carried out with the time corresponding to sample ions spectral peak
Analyze.
But by time spectrum detector response time restriction during actual acquisition, it is impossible to exceed the time of detecting system
Response speed, the sample similar for mobility is distinguished limited in one's ability.The gain bandwidth of testing circuit in addition, ion is in inspection
The analytical performance of instrument itself all can be had an impact by the electric field change that the attaching process surveyed and metal detection electrode cause.The opposing party
Face, researcher typically determines ion motion process in migration tube by Computer Simulation.Utilizing experiment to ion migration
When spectral theory is proved, motor process can only be deduced from the transient state migration time spectrogram that ion arrives at.
Summary of the invention
Present invention is primarily targeted at and overcome the deficiencies in the prior art, it is provided that a kind of space for ionic migration spectrometer
Resolution map collecting device, fluorography equipment and have the ionic migration spectrometer of the said equipment, improve ion mobility spectrometry
Power of test.
For achieving the above object, the present invention is by the following technical solutions:
A kind of spatial discrimination collection of illustrative plates collecting device for ionic migration spectrometer, including the ionization producing fluorescent samples ion
Source and the migration tube of separation sample ions, also include the reception plate being arranged at the output port of described migration tube, connect described
During receiving plate reception fluorescent samples ion, described reception plate and the output port generation relative movement of described migration tube, with
The region, different plate face making described reception plate captures the fluorescent samples ion arriving at described reception plate by mobility order successively, its
Described in the speed of relative movement more than or equal to fluorescent samples ion movement rate in described migration tube, thus described
Receive and launch on plate to hit fluorescent samples ion thereon.
Further:
Described reception plate is the rotating disk being coupled to drive mechanism, during receiving fluorescent samples ion, and described driving
Mechanism drives described rotating disk to rotate in one direction.
The receiving plane moving direction of described reception plate is perpendicular to the motion of the fluorescent samples ion exported from described migration tube
Direction.
The sheet material of described reception plate for do not affect ionic migration spectrometer normal applied electric field distribution and can adhere to sample from
The material of son.
The ion gate controlling described ionization source in a gatherer process periodically turns on, and the time point every time opened is equal
Turn to the time point of certain particular point of rotation corresponding to described rotating disk, the duration every time opened is not more than described rotating disk and rotates
The time of one week.
Described ionization source is the soft ionization source that ionization mode does not affect testing sample fluorescent characteristic.
The fluorography equipment that a kind of Yu described spatial discrimination collection of illustrative plates collecting device ion complex uses, including exciting light
Source and fluorescent samples spectrogram filming apparatus, excitation light irradiation on described reception plate, is made described reception plate by described excitation source
On fluorescent samples send fluorescent photon, described fluorescent samples spectrogram filming apparatus shoots the fluorescent samples spectrum on described reception plate
Figure, to obtain described spatial discrimination spectrogram.
Further:
Being provided with semi-transparent semi-reflecting lens between described excitation source and described reception plate, what described excitation source sent excites
Semi-transparent semi-reflecting lens described in light transmission is radiated on described reception plate, the described fluorescent samples stimulated radiation on described reception plate glimmering
Light photon reflects in the direction of described fluorescent samples spectrogram filming apparatus through described semi-transparent semi-reflecting lens, it is preferable that swash described
The convex lens of excitation beam for obtaining predetermined diameter it is provided with between luminous source and described semi-transparent semi-reflecting lens.
Filter mirror it is provided with by predetermined model between described fluorescent samples spectrogram filming apparatus and described semi-transparent semi-reflecting lens
The exciting light of the low band enclosed is removed.
A kind of ionic migration spectrometer, including described spatial discrimination collection of illustrative plates collecting device and described fluorography equipment.
Beneficial effects of the present invention:
Nature examination and resolution capability owing to fluorescent samples molecule has specific elemental composition and space structure, to it
Research process intermediate ion mobility spectrometer the mobility of tie element can be provided and mobility can be utilized sample to be carried out point
Distinguish and screen.But the sample message that the mode of simple time step resolution spectrogram obtains in terms of resolution capability with result has
Limit, needs special method to be improved with means.The present invention provides a kind of spatial discrimination collection of illustrative plates for ionic migration spectrometer
Collecting device, fluorography equipment and have the ionic migration spectrometer of the said equipment, change the tradition inspection of ionic migration spectrometer
Survey mode, for fluorescent characteristic molecule, obtains the spatial discrimination spectrogram of sample in ionic migration spectrometer, thus overcomes ion to move
Move spectrometer and use the drawback of time spectrum detection, be effectively improved the power of test of ion mobility spectrometry.
Accompanying drawing explanation
Fig. 1 is the structural representation of the spatial discrimination collection of illustrative plates collecting device of an embodiment of the present invention；
Fig. 2 be an embodiment of the present invention the structural representation of fluorography equipment；
Fig. 3 is the spatial discrimination spectrogram that a kind of specific embodiment of the present invention is obtained.
Description of reference numerals:
1-ionization source, 2-migration tube, 3-servomotor, 4-power transmission shaft, 5-receives plate, 6-semi-transparent semi-reflecting lens, 7-filter mirror,
8-excitation source, 9,10-convex lens, 11-camera, 12-camera lens.
Detailed description of the invention
Hereinafter embodiments of the present invention are elaborated.It is emphasized that what the description below was merely exemplary,
Rather than in order to limit the scope of the present invention and application thereof.
Refering to Fig. 1 and Fig. 2, in one embodiment, a kind of spatial discrimination collection of illustrative plates collection for ionic migration spectrometer sets
Standby, including producing the ionization source 1 of fluorescent samples ion and separating the migration tube 2 of sample ions, also include being arranged at described migration
Reception plate 5 at the output port of pipe 2, during described reception plate 5 receives fluorescent samples ion, described reception plate 5 with
The output port generation relative movement of described migration tube 2, so that the region, different plate face of described reception plate captures successively by migration
Rate order arrives at the fluorescent samples ion of described reception plate, the speed of wherein said relative movement more than or equal to fluorescent samples from
The movement rate of son, thus launch to hit fluorescent samples ion thereon on described reception plate 5.
In a particular embodiment, it is achieved described relative movement mode both can be to drive reception plate 5 to move relative to migration tube 2
Dynamic, it is also possible to be to drive migration tube 2 to move relative to receiving plate 5, it is also possible to drive both to move simultaneously.
In a preferred embodiment, described reception plate 5 is the rotating disk being coupled to drive mechanism, is receiving fluorescent samples ion
During, described drive mechanism drives described rotating disk to rotate in one direction.Specifically, drive mechanism can include servo electricity
Machine 3, servomotor 3 drives turntable rotation by power transmission shaft 4.In further embodiments, it would however also be possible to employ linearly moving connect
Receive plate.
In a preferred embodiment, the receiving plane moving direction of described reception plate 5 is perpendicular to from the output of described migration tube 2
The direction of motion of fluorescent samples ion.It is preferred that receiving plane and receiving plane moving direction are on the same face.Such as, receiving plate 5 is
Rotating disk, disc surfaces is perpendicular to the direction of motion of fluorescent samples ion, the rotating shaft of rotating disk and the direction of motion of fluorescent samples ion
Parallel.
In a preferred embodiment, the sheet material of described reception plate 5 divides for not affecting the normal applied electric field of ionic migration spectrometer
Cloth and the material of sample ions can be adhered to.Described reception plate 5 can be cardboard, glass plate or rubber slab etc..Receive the tool of plate 5
Shape can determine according to the actual requirements.
In a preferred embodiment, the ion gate controlling described ionization source 1 in a gatherer process periodically turns on,
The time point every time opened both corresponds to described rotating disk and turns to the time point of certain particular point of rotation, the duration every time opened
It is not more than described rotating disk and rotates the time of one week.
In a preferred embodiment, described ionization source 1 uses ionization mode not affect the soft of testing sample fluorescent characteristic
Ionization source.Ionization source 1 can be electron spray (ESI) ionization source.
The fluorography equipment that a kind of Yu described spatial discrimination collection of illustrative plates collecting device ion complex uses, including exciting light
Source and fluorescent samples spectrogram filming apparatus, excitation light irradiation on described reception plate 5, is made described reception plate by described excitation source
Fluorescent samples on 5 sends fluorescent photon, and described fluorescent samples spectrogram filming apparatus shoots the fluorescent samples on described reception plate 5
Spectrogram, to obtain described spatial discrimination spectrogram.Fluorescent samples spectrogram filming apparatus can include camera 11 and camera lens 12.
In a preferred embodiment, between described excitation source 8 and described reception plate 5, semi-transparent semi-reflecting lens 6, institute it are provided with
State the exciting light that excitation source 8 sends to be radiated on described reception plate 5, on described reception plate 5 through described semi-transparent semi-reflecting lens 6
The fluorescent photon of described fluorescent samples stimulated radiation reflects in described fluorescent samples spectrogram shooting dress through described semi-transparent semi-reflecting lens 6
The direction put, it is preferable that be provided with convex lens 9,10 between described excitation source 8 and described semi-transparent semi-reflecting lens 6, be used for obtaining
The excitation beam of predetermined diameter.
In a preferred embodiment, arrange between described fluorescent samples spectrogram filming apparatus and described semi-transparent semi-reflecting lens 6
Having filter mirror 7, filter mirror 7 is for removing the exciting light of the low band of preset range.
A kind of ionic migration spectrometer, including described spatial discrimination collection of illustrative plates collecting device and described fluorography equipment.
In certain embodiments, the sample used by spatial discrimination collection of illustrative plates collecting device is that its sample ions has in certain wave
Section light irradiate be issued to radiation transistion produced by the first electron excitation singlet state and with the fluorescent samples of luminous power.Ionization
Source uses soft ionization source to make sample ionization, in order to avoid affecting testing sample fluorescent characteristic.Ionic migration spectrometer utilizes ion to float
The difference of shift time carries out separation and the judgement of sample ions.Corresponding with Conventional temporal spectrogram, spatial discrimination spectrogram refers to
It is with space length for a digit separator ionic strength.
In certain embodiments, the fluorescent samples that fluorography device is received on plate 5 by excitation light irradiation makes it send
Fluorescent photon, receives the fluorescent samples spectrogram on plate 5 under the front receiving plate 5 uses camera shooting.Wherein video camera with
Receiving and utilize high-pass filtering mirror to be removed by the exciting light of low band between plate 5, overall developing process is at impermeable extraneous natural light
Carry out in darkroom.
Example
(1) the migration tube diameter 16mm of ion mobility spectrometry, apparatus structure makes outer edge and the migration tube internal diameter outer of rotating disk
The most tangent.Using radius is that 10cm glass disk substitutes traditional detector, ion gate opening time 300 μ as receiving plate
m.After enabling, sample ions remains a constant speed substantially to receiving plate motion after one section of variable accelerated motion of experience in migration tube, receives
Plate capture successively strike against the ion on its surface and keep not interfering ion surface take off reception plate.It is positioned over fluorography dress
In putting, in camera, photographed this sample spatial discrimination spectrogram case at ion mobility spectrometry.
(2) wherein receiving mark scale on plate, triggering ion gate every time when this scale runs to 12 directions and open,
Receive angular velocity of satellite motion on the rotation roulette of plate place and keep stable.
(3) wherein sample is the RHODAMINE 6G (Shanghai Jing Chun biochemical technology limited company) with the characteristics of luminescence
Soluble in water and methanol, a kind of dyestuff luminous in yellow green, it is used widely in chemical industry.Apply electron spray ionisation source
5kV voltage, migration tube voltage is 50V/mm.
(4) excitation source sends 473nm laser, obtains 30mm diameter beam through expanding, and excites the fluorescence received on plate
Sample.The fluorescent photon of sample stimulated radiation reflects in camera direction through semi-transparent semi-reflecting lens.Camera mirror after filtering and camera lens
The light reflected is filtered and collects and obtains spectrogram, as shown in Figure 3.
Above content is to combine concrete/further description the most made for the present invention, it is impossible to recognize
Determine the present invention be embodied as be confined to these explanations.For general technical staff of the technical field of the invention,
Without departing from the inventive concept of the premise, these embodiments having described that can also be made some replacements or modification by it,
And these substitute or variant all should be considered as belonging to protection scope of the present invention.
Claims (10)
1. for a spatial discrimination collection of illustrative plates collecting device for ionic migration spectrometer, including the ionization source producing fluorescent samples ion
With the migration tube separating fluorescent samples ion, it is characterised in that also include being arranged at connecing at the output port of described migration tube
Receiving plate, receive during fluorescent samples ion at described reception plate, the output port of described reception plate and described migration tube is sent out
Raw relative movement, so that the region, different plate face of described reception plate captures successively and arrives at the glimmering of described reception plate by mobility order
Light sample ions, the speed of wherein said relative movement is more than or equal to the movement rate of fluorescent samples ion, thus described
Receive and launch on plate to hit fluorescent samples ion thereon.
2. spatial discrimination collection of illustrative plates collecting device as claimed in claim 1, it is characterised in that described reception plate is for being coupled to drive
The rotating disk of mechanism, during receiving fluorescent samples ion, described drive mechanism drives described rotating disk to rotate in one direction.
3. spatial discrimination collection of illustrative plates collecting device as claimed in claim 1, it is characterised in that the receiving plane of described reception plate moves
Direction is perpendicular to the direction of motion of the fluorescent samples ion exported from described migration tube.
4. spatial discrimination collection of illustrative plates collecting device as claimed in claim 1, it is characterised in that the sheet material of described reception plate is not shadow
Ring the distribution of ionic migration spectrometer normal applied electric field and the material of sample ions can be adhered to.
5. the spatial discrimination collection of illustrative plates collecting device as described in any one of claim 2 to 4, it is characterised in that once gathering
The ion gate controlling described ionization source in journey periodically turns on, and the time point every time opened both corresponds to described rotating disk and turns to
The time point of certain particular point of rotation, the duration every time opened is not more than described rotating disk and rotates the time of one week.
6. spatial discrimination collection of illustrative plates collecting device as claimed in claim 1, it is characterised in that described ionization source be ionization mode not
Affect the soft ionization source of testing sample fluorescent characteristic.
7. the fluorescence used with the spatial discrimination collection of illustrative plates collecting device ion complex described in any one of claim 1 to 6 shows
Shadow equipment, it is characterised in that including excitation source and fluorescent samples spectrogram filming apparatus, described excitation source is by excitation light irradiation
On described reception plate, the fluorescent samples on described reception plate is made to send fluorescent photon, described fluorescent samples spectrogram filming apparatus
Shoot the fluorescent samples spectrogram on described reception plate, to obtain described spatial discrimination spectrogram.
8. the fluorography equipment that spatial discrimination collection of illustrative plates collecting device ion complex as claimed in claim 7 uses, its feature
It is, between described excitation source and described reception plate, is provided with semi-transparent semi-reflecting lens, the exciting light that described excitation source sends
It is radiated on described reception plate through described semi-transparent semi-reflecting lens, the fluorescence of the described fluorescent samples stimulated radiation on described reception plate
Photon reflects in the direction of described fluorescent samples spectrogram filming apparatus through described semi-transparent semi-reflecting lens, it is preferable that excite described
The convex lens of excitation beam for obtaining predetermined diameter it is provided with between light source and described semi-transparent semi-reflecting lens.
9. the fluorography equipment that spatial discrimination collection of illustrative plates collecting device ion complex as claimed in claim 8 uses, its feature
It is, between described fluorescent samples spectrogram filming apparatus and described semi-transparent semi-reflecting lens, is provided with filter mirror with by preset range
The exciting light of low band is removed.
10. an ionic migration spectrometer, it is characterised in that include that the spatial discrimination collection of illustrative plates described in any one of claim 1 to 6 is adopted
Fluorography equipment described in collection equipment and any one of claim 7 to 9.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610343841.1A CN106053587B (en) | 2016-05-23 | 2016-05-23 | Spatial discrimination map acquires equipment, fluorography equipment and ionic migration spectrometer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610343841.1A CN106053587B (en) | 2016-05-23 | 2016-05-23 | Spatial discrimination map acquires equipment, fluorography equipment and ionic migration spectrometer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106053587A true CN106053587A (en) | 2016-10-26 |
| CN106053587B CN106053587B (en) | 2019-01-11 |
Family
ID=57176566
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610343841.1A Active CN106053587B (en) | 2016-05-23 | 2016-05-23 | Spatial discrimination map acquires equipment, fluorography equipment and ionic migration spectrometer |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106053587B (en) |
Citations (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0447158A2 (en) * | 1990-03-13 | 1991-09-18 | Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Revenue | Detector for concealed explosive or narcotic substances |
| US5345809A (en) * | 1989-06-09 | 1994-09-13 | Research Corporation Technologies, Inc. | Explosive detection screening system |
| US20030132379A1 (en) * | 2002-01-17 | 2003-07-17 | Gangqiang Li | Ion mobility spectrometer with high ion transmission efficiency |
| CN1774623A (en) * | 2002-07-31 | 2006-05-17 | 阿尔利克斯公司 | System and method of sorting materials using holographic laser steering |
| CN101082601A (en) * | 2006-05-31 | 2007-12-05 | 中国科学院电子学研究所 | Microcomputer electric surface ionization source used for ion migration ratio instrument |
| CN101363839A (en) * | 2008-09-12 | 2009-02-11 | 首都师范大学 | Non-damage micrometering system for observating biological sample with fluorescent |
| WO2009094059A2 (en) * | 2007-11-06 | 2009-07-30 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Sensitive ion detection device and method for analysis of compounds as vapors in gases |
| US20120032071A1 (en) * | 2008-03-20 | 2012-02-09 | The Mitre Corporation | Multi-modal particle detector |
| CN103887141A (en) * | 2014-03-25 | 2014-06-25 | 清华大学深圳研究生院 | Ionic migration spectrometer |
| CN105181782A (en) * | 2015-10-09 | 2015-12-23 | 中国船舶重工集团公司第七一〇研究所 | Array type detecting plate for ion mobility spectrometry, detecting system and detecting method |
| CN105353023A (en) * | 2014-08-20 | 2016-02-24 | 布鲁克道尔顿公司 | Ion mobility spectrometry mobility axis correction method and ion mobility spectrometry mobility axis correction instrument |
-
2016
- 2016-05-23 CN CN201610343841.1A patent/CN106053587B/en active Active
Patent Citations (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5345809A (en) * | 1989-06-09 | 1994-09-13 | Research Corporation Technologies, Inc. | Explosive detection screening system |
| EP0447158A2 (en) * | 1990-03-13 | 1991-09-18 | Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Revenue | Detector for concealed explosive or narcotic substances |
| US20030132379A1 (en) * | 2002-01-17 | 2003-07-17 | Gangqiang Li | Ion mobility spectrometer with high ion transmission efficiency |
| CN1774623A (en) * | 2002-07-31 | 2006-05-17 | 阿尔利克斯公司 | System and method of sorting materials using holographic laser steering |
| CN101082601A (en) * | 2006-05-31 | 2007-12-05 | 中国科学院电子学研究所 | Microcomputer electric surface ionization source used for ion migration ratio instrument |
| WO2009094059A2 (en) * | 2007-11-06 | 2009-07-30 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Sensitive ion detection device and method for analysis of compounds as vapors in gases |
| US20120032071A1 (en) * | 2008-03-20 | 2012-02-09 | The Mitre Corporation | Multi-modal particle detector |
| CN101363839A (en) * | 2008-09-12 | 2009-02-11 | 首都师范大学 | Non-damage micrometering system for observating biological sample with fluorescent |
| CN103887141A (en) * | 2014-03-25 | 2014-06-25 | 清华大学深圳研究生院 | Ionic migration spectrometer |
| CN105353023A (en) * | 2014-08-20 | 2016-02-24 | 布鲁克道尔顿公司 | Ion mobility spectrometry mobility axis correction method and ion mobility spectrometry mobility axis correction instrument |
| CN105181782A (en) * | 2015-10-09 | 2015-12-23 | 中国船舶重工集团公司第七一〇研究所 | Array type detecting plate for ion mobility spectrometry, detecting system and detecting method |
Also Published As
| Publication number | Publication date |
|---|---|
| CN106053587B (en) | 2019-01-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101356432A (en) | Ion trap mobility spectrometer | |
| CN108459013A (en) | Sample detection means based on laser induced breakdown spectroscopy | |
| CN103604789A (en) | Fluorescent powder performance test system and test method | |
| CN103940898B (en) | A kind of micro-mass spectrum imaging stage apparatus and formation method thereof | |
| WO2012051813A1 (en) | Method for determining boron isotopic composition with positive thermal ionization mass spectrometer by static double-collection | |
| CN103972021A (en) | Momentum analyzer based time-of-flight mass spectrometer | |
| CN106053587B (en) | Spatial discrimination map acquires equipment, fluorography equipment and ionic migration spectrometer | |
| CN206340512U (en) | Laser desorption ionisation mass spectrometric apparatus | |
| EP2235738A2 (en) | Ion spectrum analysing apparatus and method | |
| WO2014017544A1 (en) | Element analyzing device | |
| CN201152867Y (en) | Infrared laser desorption/vacuum ultraviolet single photon ionization mass spectrometry analytical equipment | |
| CN106783508B (en) | The method of transference tube and operation transference tube | |
| CN102290319B (en) | Dual-ion trap mass spectrometer | |
| CN109427535A (en) | Aerosol mass spectrometer | |
| CN209843661U (en) | Matrix-assisted laser desorption ionization time-of-flight mass spectrometer | |
| CN108169320A (en) | The laser mass spectrometry measuring method of one trace elements and normal pressure open type Portable laser mass spectrograph | |
| CN107946167A (en) | A kind of metal complex mass spectrometer | |
| CN105403614B (en) | The tracer method that mobile ion is distributed in ionic migration spectrometer | |
| JP3683156B2 (en) | Method for surface analysis of solid materials | |
| CN109632939A (en) | A kind of method and its system using ion probe measurement inert gas | |
| CN208157358U (en) | External electromagnetic field normal pressure open-type laser mass spectrograph | |
| CN103887143A (en) | Ion mobility spectrometer based on ion sweep type membrane sample introduction | |
| Nan-Nan et al. | Detection of plasticizers in soil using surface desorption atmospheric pressure chemical ionization imaging mass spectrometry | |
| CN202796851U (en) | Ion source combining thermal desorption with electron impact | |
| CN108303457B (en) | Instrument and method for ionosphere H, he isotope measurement |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |