CN103887143A - Ion mobility spectrometer based on ion sweep type membrane sample introduction - Google Patents
Ion mobility spectrometer based on ion sweep type membrane sample introduction Download PDFInfo
- Publication number
- CN103887143A CN103887143A CN201210555933.8A CN201210555933A CN103887143A CN 103887143 A CN103887143 A CN 103887143A CN 201210555933 A CN201210555933 A CN 201210555933A CN 103887143 A CN103887143 A CN 103887143A
- Authority
- CN
- China
- Prior art keywords
- ion
- sample introduction
- ionization
- casing
- spectrometer based
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Landscapes
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Abstract
The invention designs an ion mobility spectrometer based on ion sweep type membrane sample introduction. The ion mobility spectrometer comprises a membrane sample introduction device, an ionization source, an ionization reaction region, an ion gate, an ion mobility region, a grid, and an ion receiving pole. The adopted technical means comprises the following steps: the membrane sample introduction device is located in the ionization reaction region; reactive ions generated under the action of the ionization source sweep the membrane surface exposed on the ionization reaction region; and an electric field is arranged in front of and behind the membrane device. Thus, the membrane sample introduction device sample transmittance and transmittance speed and instrument response speed and sensitivity can be effectively improved.
Description
Technical field
The present invention relates to a kind of ionic migration spectrometer based on ion blowing and sweeping type film sample introduction, effectively improve the transmitance of film sampling device to sample and response speed and the sensitivity of penetration speed and instrument.
Background technology
Ion mobility spectrometry (Ion Mobility Spectrometry, IMS) technology is that the one that 20 century 70s occur separates detection technique, compared with the conventional art such as mass spectrum, chromatogram, it has the features such as simple in structure, highly sensitive, analysis speed is fast, is suitable for on-the-spot use.Ionic migration spectrometer is mainly made up of ion source, ion gate, migration area and detector.Ion source makes sample molecule, N
2, O
2with steam ionization, the ion of generation is easy to and molecule generation ion molecule reaction, obtains multi-products ion.The ion gate that ion is opened by periodicity under the ordering about of electric field enters migration area, floating gas molecule with the neutrality of adverse current constantly collides, because these ions have different migration rates in electric field, different ions is separated, successively arrive detector.
Film sampling device, for ion mobility spectrometry provides a kind of direct, continuous input mode, has advanced the application of ion mobility spectrometry in continuous on-line monitoring field.Meanwhile, due to the existence of pellicle, can effectively prevent that particle and steam from entering ion mobility spectrometry, reach part and eliminated the effect of disturbing.Generally, sample molecule need leave film surface after seeing through pellicle under the effect of carrier gas, but the carrier gas of little flow velocity can not be taken away the sample molecule on film surface in time, thereby cause the sample concentration difference in outside in film to reduce gradually, reduced transmitance and the penetration speed of sample; The carrier gas of excessive flow velocity can play diluting effect to sample, thus the sensitivity of lowering apparatus.
Thus, the present invention has designed a kind of ionic migration spectrometer based on ion blowing and sweeping type film sample introduction.Sample sees through pellicle with the form of molecule, and under the purging effect of reactive ion, molecule ionizes on film surface; The ion film surface that speeds away under the acting in conjunction of electric field and carrier gas, has improved the sample concentration difference of the inside and outside both sides of film before and after the film sampling device, thus transmitance and the penetration speed of raising sample in film sampling device.
Summary of the invention
The object of the present invention is to provide a kind of ionic migration spectrometer based on ion blowing and sweeping type film sample introduction.
Based on an ionic migration spectrometer for ion blowing and sweeping type film sample introduction, comprise film sampling device and ion mobility spectrometry, ion mobility spectrometry comprises ionization source, ionization reaction district, ion gate, ion migration area, aperture plate, the ion receiving pole of arranging successively.
Film sampling device is an end opening, the airtight casing of the other end, and the openend of casing is provided with pellicle, and casing is provided with air inlet and gas outlet, and the openend of casing is placed in the ionization reaction district of ion mobility spectrometry; Pellicle is distinguished the ionization reaction of the internal chamber of casing and ion mobility spectrometry to separate, and they are not communicated with mutually; The reactive ion generating under ionization source effect purges the film surface that is exposed to ionization reaction district, and sample molecule is ionized on film surface.
Ionization reaction district comprises two above electrode retaining collars, and film sampling device is arranged between two electrode retaining collars, and two electrode retaining collars connect extraneous direct voltage by wire respectively.
Pellicle in film sampling device is the silicone rubber membrane of plane or tubulose.
Ionization source is radioactive ionization gauge source or light ionization source or discharge ionization source.
In the time that ionization source is light ionization source, in carrier gas, add dopant for generation of reactive ion.
Dopant is acetone, ethanol, toluene.
The air inlet of casing is connected with sample gas source of the gas by pipeline, the gas outlet emptying of casing or connect receiving flask by pipeline.
Air inlet or gas outlet place in casing are provided with sampling pump.Advantage of the present invention:
The reactive ion generating under ionization source effect purges the film surface that is exposed to ionization reaction district, sample molecule is ionized on film surface, the ion film surface that speeds away under the acting in conjunction of electric field and carrier gas generating, keep the maximum sample concentration difference of film both sides, improve transmitance and the penetration speed of film sampling device to sample, thereby improve sensitivity and the response speed of instrument.
Accompanying drawing explanation
Fig. 1 is the 3 kind structural representations of the present invention while adopting planar film.
Fig. 2 is the 2 kind structural representations of the present invention while adopting tubular film.
Fig. 3 is radioactive ionization gauge source structure schematic diagram.
Fig. 4 is light ionization source structural representation.
Fig. 5 is discharge ionization source structural representation.
Embodiment
The invention provides a kind of ionic migration spectrometer based on ion blowing and sweeping type film sample introduction.
Film sampling device is an end opening, the airtight casing of the other end, and the openend of casing is provided with pellicle, and casing is provided with air inlet and gas outlet, and the openend of casing is placed in the ionization reaction district of ion mobility spectrometry; Pellicle is distinguished the ionization reaction of the internal chamber of casing and ion mobility spectrometry to separate, and they are not communicated with mutually; The reactive ion generating under ionization source effect purges the film surface that is exposed to ionization reaction district, and sample molecule is ionized on film surface.
Ionization reaction district comprises two above electrode retaining collars, and film sampling device is arranged between two electrode retaining collars, and two electrode retaining collars connect extraneous direct voltage by wire respectively.
Pellicle in film sampling device is the silicone rubber membrane of plane or tubulose.
Ionization source is radioactive ionization gauge source or light ionization source or discharge ionization source.
In the time that ionization source is light ionization source, in carrier gas, add dopant for generation of reactive ion.
Dopant is acetone, ethanol, toluene.
The air inlet of casing is connected with sample gas source of the gas by pipeline, the gas outlet emptying of casing or connect receiving flask by pipeline.
Air inlet or gas outlet place in casing are provided with sampling pump.
As depicted in figs. 1 and 2, wherein 1 is ionization source, 2 ionization reaction districts, 3 ion migration areas, 4 is electrode retaining collar, 5 is dead ring, 6 is ion gate, and 7 is aperture plate, and 8 is ion receiving pole, 9 is pellicle, 10 is sample air inlet, and 11 is sample gas outlet, and 12 is carrier gas inlet, 13 for floating gas entrance, and 14 is gas outlet.Sample enters film sampling device from sample air inlet, and its molecule sees through pellicle under the effect of concentration difference; The reactive ion generating under ionization source effect directly purges the film surface that is exposed to ionization reaction district, sample molecule is above ionized, the ion film surface that speeds away under the acting in conjunction of front and back electric field and carrier gas generating, keep the maximum sample concentration difference of film both sides, improved transmitance and the transmission rates of film sampling device to sample.The ion gate that ion was opened by the cycle enters the ion migration area being made up of uniform electric field, because different ions there are differences at aspects such as structure, quality, electric charges, therefore they have different mobilities, cause its speed difference mobile in migration area, successively reach detector, separate and detect thereby realize.
Claims (8)
1. the ionic migration spectrometer based on ion blowing and sweeping type film sample introduction, comprises film sampling device and ion mobility spectrometry, and ion mobility spectrometry comprises ionization source, ionization reaction district, ion gate, ion migration area, aperture plate, the ion receiving pole of arranging successively; It is characterized in that:
Film sampling device is an end opening, the airtight casing of the other end, and the openend of casing is provided with pellicle, and casing is provided with air inlet and gas outlet, and the openend of casing is placed in the ionization reaction district of ion mobility spectrometry; Pellicle is distinguished the ionization reaction of the internal chamber of casing and ion mobility spectrometry to separate, and they are not communicated with mutually; The reactive ion generating under ionization source effect purges the film surface that is exposed to ionization reaction district, and sample molecule is ionized on film surface.
2. the ionic migration spectrometer based on ion blowing and sweeping type film sample introduction according to claim 1, it is characterized in that: ionization reaction district comprises two above electrode retaining collars, film sampling device is arranged between two electrode retaining collars, and two electrode retaining collars connect extraneous direct voltage by wire respectively.
3. the ionic migration spectrometer based on ion blowing and sweeping type film sample introduction according to claim 1, is characterized in that: the pellicle in film sampling device is the silicone rubber membrane of plane or tubulose.
4. the ionic migration spectrometer based on ion blowing and sweeping type film sample introduction according to claim 1, is characterized in that: ionization source is radioactive ionization gauge source or light ionization source or discharge ionization source.
5. the ionic migration spectrometer based on ion blowing and sweeping type film sample introduction according to claim 4, is characterized in that: in the time that ionization source is light ionization source, add dopant for generation of reactive ion in carrier gas.
6. the ionic migration spectrometer based on ion blowing and sweeping type film sample introduction according to claim 5, is characterized in that: dopant is acetone, ethanol, toluene.
7. the ionic migration spectrometer based on ion blowing and sweeping type film sample introduction according to claim 1, is characterized in that: the air inlet of casing is connected with sample gas source of the gas by pipeline, the gas outlet emptying of casing or connect receiving flask by pipeline.
8. the ionic migration spectrometer based on ion blowing and sweeping type film sample introduction according to claim 1, is characterized in that: air inlet or gas outlet place in casing are provided with sampling pump.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210555933.8A CN103887143A (en) | 2012-12-19 | 2012-12-19 | Ion mobility spectrometer based on ion sweep type membrane sample introduction |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210555933.8A CN103887143A (en) | 2012-12-19 | 2012-12-19 | Ion mobility spectrometer based on ion sweep type membrane sample introduction |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103887143A true CN103887143A (en) | 2014-06-25 |
Family
ID=50955981
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210555933.8A Pending CN103887143A (en) | 2012-12-19 | 2012-12-19 | Ion mobility spectrometer based on ion sweep type membrane sample introduction |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103887143A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107941897A (en) * | 2017-11-30 | 2018-04-20 | 北京市北分仪器技术有限责任公司 | A kind of bipolarity controllable pulse corona discharge ionization source and its ionic migration spectrometer |
| CN111199867A (en) * | 2018-11-20 | 2020-05-26 | 中国科学院大连化学物理研究所 | Low discrimination ion gate and control method |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1916619A (en) * | 2005-08-19 | 2007-02-21 | 上海新漫传感技术研究发展有限公司 | Ion migration spectrometer based on sample through membrane |
| CN101113968A (en) * | 2006-07-27 | 2008-01-30 | 中国科学院大连化学物理研究所 | Method for on-line measuring drug-making chemicals with ion transfer spectrometer |
| CN101629933A (en) * | 2008-07-16 | 2010-01-20 | 同方威视技术股份有限公司 | Ion mobility spectrometer |
| CN101667518A (en) * | 2008-09-05 | 2010-03-10 | 中国科学院大连化学物理研究所 | Photoemission ionization source and application thereof in mass spectrometry or ion mobility spectrometry |
| CN102103124A (en) * | 2009-12-18 | 2011-06-22 | 中国科学院大连化学物理研究所 | Method for quickly analyzing organic pollutant in liquid on line by using micro mass spectrometer |
| CN201935894U (en) * | 2010-12-31 | 2011-08-17 | 同方威视技术股份有限公司 | Ion mobility spectrometry and sample injection device used for same |
| CN202423215U (en) * | 2011-12-16 | 2012-09-05 | 中国科学院大连化学物理研究所 | Gas film sampling device of ion mobility spectrometry |
| CN103854951A (en) * | 2012-12-06 | 2014-06-11 | 中国科学院大连化学物理研究所 | High-field asymmetric waveform ion mobility spectrometer with film purging sample introduction function |
-
2012
- 2012-12-19 CN CN201210555933.8A patent/CN103887143A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1916619A (en) * | 2005-08-19 | 2007-02-21 | 上海新漫传感技术研究发展有限公司 | Ion migration spectrometer based on sample through membrane |
| CN101113968A (en) * | 2006-07-27 | 2008-01-30 | 中国科学院大连化学物理研究所 | Method for on-line measuring drug-making chemicals with ion transfer spectrometer |
| CN101629933A (en) * | 2008-07-16 | 2010-01-20 | 同方威视技术股份有限公司 | Ion mobility spectrometer |
| CN101667518A (en) * | 2008-09-05 | 2010-03-10 | 中国科学院大连化学物理研究所 | Photoemission ionization source and application thereof in mass spectrometry or ion mobility spectrometry |
| CN102103124A (en) * | 2009-12-18 | 2011-06-22 | 中国科学院大连化学物理研究所 | Method for quickly analyzing organic pollutant in liquid on line by using micro mass spectrometer |
| CN201935894U (en) * | 2010-12-31 | 2011-08-17 | 同方威视技术股份有限公司 | Ion mobility spectrometry and sample injection device used for same |
| CN202423215U (en) * | 2011-12-16 | 2012-09-05 | 中国科学院大连化学物理研究所 | Gas film sampling device of ion mobility spectrometry |
| CN103854951A (en) * | 2012-12-06 | 2014-06-11 | 中国科学院大连化学物理研究所 | High-field asymmetric waveform ion mobility spectrometer with film purging sample introduction function |
Non-Patent Citations (2)
| Title |
|---|
| MADS LETH等: "A fully integrated trap-membrane inlet mass spectrometry system for the measurement of semivolatile organic compounds in aqueous solution", 《RAPID COMMUNICATIONS IN MASS SPECTROMETRY》, vol. 9, no. 7, 31 December 1995 (1995-12-31), pages 591 - 596 * |
| RENATO HADDAD等: "Easy Ambient Sonic-Spray Ionization-Membrane Interface Mass Spectrometry for Direct Analysis of Solution Constituents", 《ANALYTICAL CHEMISTRY》, vol. 80, no. 3, 1 August 2008 (2008-08-01), pages 898 - 903 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107941897A (en) * | 2017-11-30 | 2018-04-20 | 北京市北分仪器技术有限责任公司 | A kind of bipolarity controllable pulse corona discharge ionization source and its ionic migration spectrometer |
| CN107941897B (en) * | 2017-11-30 | 2024-01-02 | 北京市北分仪器技术有限责任公司 | Bipolar controllable pulse corona discharge ionization source and ion mobility spectrometer thereof |
| CN111199867A (en) * | 2018-11-20 | 2020-05-26 | 中国科学院大连化学物理研究所 | Low discrimination ion gate and control method |
| CN111199867B (en) * | 2018-11-20 | 2020-11-20 | 中国科学院大连化学物理研究所 | Low discrimination ion gate and control method |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2673670C1 (en) | Concentric apci surface ionization ion source, ion guide and method of use | |
| KR101434496B1 (en) | Detection Apparatus | |
| CN103380371B (en) | Utilize method and the device of Ion Mobility Spectroscopy technology for detection and discriminating gas | |
| CN108072690B (en) | Ion mobility spectrometry and ion trap mass spectrometry combined device and analysis method | |
| JP6625675B2 (en) | Sample probe inlet flow system | |
| CN102455318A (en) | Continuous monitor for detecting aerosol sample | |
| CN103871823A (en) | Membrane-inlet ion mobility spectrometer doped with organic solvent | |
| CN101113968A (en) | Method for on-line measuring drug-making chemicals with ion transfer spectrometer | |
| CN104880393A (en) | Device and method for measuring PM 2.5 of specific places | |
| JP2002373615A (en) | Ion source and mass spectrometer using the same | |
| CN202423215U (en) | Gas film sampling device of ion mobility spectrometry | |
| CN201903529U (en) | Continuous online ionic migration spectrum monitoring instrument for poisonous gases | |
| CN103887143A (en) | Ion mobility spectrometer based on ion sweep type membrane sample introduction | |
| CN101583868A (en) | Detector apparatus and pre-concentrators | |
| CN103698387B (en) | For the sampling device of ionic migration spectrometer and using method thereof and ionic migration spectrometer | |
| CN105632865B (en) | A kind of on-radiation transference tube | |
| JP2016530517A5 (en) | ||
| CN201837611U (en) | Detector for trace explosive on surface of certificate | |
| CN108088891A (en) | A kind of ion mobility spectrometry and operating method for being disposed vertically VUV radio-frequency lamps | |
| CN104716006A (en) | Connector shared by ion migration spectrum and mass spectrum | |
| CN103776893B (en) | A kind of dielectric barrier discharge ionization source ionic migration spectrometer | |
| CN108007999A (en) | A kind of ionic migration spectrum detection method of Etomidate in Etomidate Injection | |
| CN104716013A (en) | Novel high-field asymmetric ion mobility spectrometry device | |
| FI20205122A1 (en) | Method and apparatus for monitoring number density of aerosol particles | |
| CN103871827A (en) | Crossing type ion migration tube |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20140625 |