CN104716006A - Connector shared by ion migration spectrum and mass spectrum - Google Patents
Connector shared by ion migration spectrum and mass spectrum Download PDFInfo
- Publication number
- CN104716006A CN104716006A CN201310691002.5A CN201310691002A CN104716006A CN 104716006 A CN104716006 A CN 104716006A CN 201310691002 A CN201310691002 A CN 201310691002A CN 104716006 A CN104716006 A CN 104716006A
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- China
- Prior art keywords
- plate
- ion mobility
- ion
- faraday
- interface
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Classifications
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/06—Electron- or ion-optical arrangements
- H01J49/067—Ion lenses, apertures, skimmers
Abstract
The invention discloses a connector shared by an ion migration spectrum and a mass spectrum. An ion receiving pole of the ion migration spectrum is a Faraday disc with a small hole in the center, and center ions enter the mass spectrum from the ion migration spectrum through the small hole for characterization analysis. A concentric ring focusing electrode is arranged on the outer side of the Faraday disc, a certain DC voltage is applied to the electrode, the number of ions passing through the small hole can be increased accordingly, and therefore the detection sensitivity of the mass spectrum is improved.
Description
Technical field
The present invention devises a kind of interface for ion mobility spectrometry and mass spectrometry.The annulus focusing electrode that the arranged outside one of Faraday plate is concentric in ion mobility spectrometry, applies certain direct voltage on this electrode and can improve number of ions by aperture, thus improve mass spectrographic detection sensitivity.
Background technology
Ion mobility spectrometry is a kind of separation detection technique that 20 century 70s occur, compared with the conventional art such as mass spectrum, chromatogram, it has the features such as structure is simple, highly sensitive, analysis speed is fast, and in addition, ion mobility spectrometry can also realize the separation of some isomer.But the resolution of ion mobility spectrometry is generally on the low side, the accurately qualitative of complex sample cannot be realized.
Mass spectrum as a kind of characterization of compound method of classics, its compound accurate qualitative in have unique advantage, but it cannot realize the discriminating of isomer.If can by ion mobility spectrometry and mass spectrometry, both can supplement mutually, broaden application scope.At present, domestic and international researcher, by ion mobility spectrometry and mass spectrometry, is applied in environment VOCs, explosive, bioprotein etc. and is separated in detection.Ye Youduo company is proposed the commercialization instrument of both couplings simultaneously.
Because ion mobility spectrometry under atmospheric pressure works, mass spectrum requires to run under vacuum conditions, therefore needs the suitable interface of design one to carry out the conversion of transition two kinds of operating air pressures.In order to ensure the vacuum degree in mass spectrometer system, normally arrange an aperture or slit at the center of ion mobility spectrometry ion receiving pole for ion penetration, the ion therefore in ion mobility spectrometry only has few part can enter mass spectrum to carry out analyzing and testing.In order to improve the transmitance of ion, the present invention devises a kind of interface for ion mobility spectrometry and mass spectrometry.The annulus focusing electrode that the arranged outside one of Faraday plate is concentric in ion mobility spectrometry, applies certain direct voltage on this electrode and can improve number of ions by aperture, thus improve mass spectrographic detection sensitivity.
Summary of the invention
The present invention devises a kind of interface for ion mobility spectrometry and mass spectrometry, comprises Faraday plate, annulus focusing electrode, aperture plate and supports insulative pad;
The center of Faraday plate is provided with a through hole, and the ion in transference tube enters mass spectrum by this through hole;
Be provided with a coaxial annulus focusing electrode outside Faraday plate, both are not communicated with mutually;
Faraday plate front end is provided with an aperture plate, there is certain interval between the two;
Outer wall near the transference tube of Faraday plate side is provided with two symmetrical drift gas air inlets;
The diameter of the supercentral through hole of Faraday plate is 0.01-5mm, and Faraday plate is connected with outer signal amplifier by holding wire;
There is certain gap between annulus focusing electrode and aperture plate, and be connected with external direct voltage by wire;
Aperture plate is connected with external direct voltage by wire;
The drift gas that described drift gas air inlet enters is one or more in air, helium, nitrogen, hydrogen.
Beneficial effect of the present invention is: the annulus focusing electrode that the arranged outside one of Faraday plate is concentric in ion mobility spectrometry, applies certain direct voltage on this electrode and can improve number of ions by aperture, thus improve mass spectrographic detection sensitivity.
Accompanying drawing explanation
Fig. 1 is structural representation of the present invention.
Wherein, 1 is ion mobility spectrometry, and 2 is mass spectrum, and 3 is aperture plate, and 4 is Faraday plate, and 5 is annulus focusing electrode, and 6 is aperture, and 7 is drift gas entrance, and 8 is supports insulative pad.
Fig. 2 is annulus focusing electrode ground connection and applying 690V direct voltage successively in the present invention, compares the O through diameter 3mm aperture
2 -ion concentration.
Embodiment
The present invention devises a kind of interface for ion mobility spectrometry and mass spectrometry, comprises Faraday plate, annulus focusing electrode, aperture plate and supports insulative pad;
The center of Faraday plate is provided with a through hole, and the ion in transference tube enters mass spectrum by this through hole;
Be provided with a coaxial annulus focusing electrode outside Faraday plate, both are not communicated with mutually;
Faraday plate front end is provided with an aperture plate, there is certain interval between the two;
Outer wall near the transference tube of Faraday plate side is provided with two symmetrical drift gas air inlets;
The diameter of the supercentral through hole of Faraday plate is 0.01-5mm, and Faraday plate is connected with outer signal amplifier by holding wire;
There is certain gap between annulus focusing electrode and aperture plate, and be connected with external direct voltage by wire;
Aperture plate is connected with external direct voltage by wire;
The drift gas that described drift gas air inlet enters is one or more in air, helium, nitrogen, hydrogen.
First ion enters in ion mobility spectrometry and is separated; Subsequently, arrived on Faraday plate by a part of ion of aperture plate and form micro-electric current, through outer signal amplifier amplify after obtain Ion transfer spectrogram, and another part ion under the effect of annulus focusing electrode to the center convergence of Faraday plate and smooth by aperture after enter mass spectrum carry out analyzing and testing with obtains output mass spectrogram.
Embodiment 1
Faraday plate hole diameter is 3mm, and annulus focusing electrode is ground connection and the direct voltage applying 690V successively, records the O arriving this aperture place respectively
2 -ion transfer spectrogram, as shown in Figure 2.Result shows, during relative to ground connection, direct voltage annulus focusing electrode applying a 690V can by O
2 -ion concentration improve nearly 1 times.
Claims (5)
1., for an interface for ion mobility spectrometry and mass spectrometry, comprise Faraday plate (4), annulus focusing electrode (5), aperture plate (3) and supports insulative pad (8), it is characterized in that:
The center of Faraday plate is provided with a through hole (6), and the ion in transference tube enters mass spectrum by this through hole (6);
Faraday plate (4) outside is provided with a coaxial annulus focusing electrode, and both are not communicated with mutually;
Faraday plate (4) front end is provided with an aperture plate (3), there is certain interval between the two;
Outer wall near the transference tube of Faraday plate (4) side is provided with two symmetrical drift gas air inlets (7).
2. the interface for ion mobility spectrometry and mass spectrometry according to claim 1, is characterized in that:
The diameter of Faraday plate (4) supercentral through hole (6) is 0.01-5mm, and Faraday plate (4) is connected with outer signal amplifier by holding wire.
3. the interface for ion mobility spectrometry and mass spectrometry according to claim 1, is characterized in that:
There is certain gap between annulus focusing electrode and aperture plate (3), and be connected with external direct voltage by wire.
4. the interface for ion mobility spectrometry and mass spectrometry according to claim 1, is characterized in that:
Aperture plate (3) is connected with external direct voltage by wire.
5. the interface for ion mobility spectrometry and mass spectrometry according to claim 1, is characterized in that:
The drift gas that described drift gas air inlet enters is one or more in air, helium, nitrogen, hydrogen.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310691002.5A CN104716006A (en) | 2013-12-13 | 2013-12-13 | Connector shared by ion migration spectrum and mass spectrum |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310691002.5A CN104716006A (en) | 2013-12-13 | 2013-12-13 | Connector shared by ion migration spectrum and mass spectrum |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104716006A true CN104716006A (en) | 2015-06-17 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310691002.5A Pending CN104716006A (en) | 2013-12-13 | 2013-12-13 | Connector shared by ion migration spectrum and mass spectrum |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104716006A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105513935A (en) * | 2016-01-13 | 2016-04-20 | 中国科学院上海有机化学研究所 | Quick ionizing method and device |
| CN106057628A (en) * | 2016-06-13 | 2016-10-26 | 塔里木大学 | Migration tube and ion mobility spectrometer with migration tube for axial focusing under atmospheric pressure |
| CN107275180A (en) * | 2017-06-29 | 2017-10-20 | 哈尔滨工业大学（威海） | Ion receiving pole |
| CN108335964A (en) * | 2017-01-20 | 2018-07-27 | 广州智纯科学仪器有限公司 | Ion mobility spectrometry and flight time mass spectrum combined instrument and its connecting interface structure |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060289745A1 (en) * | 2005-05-24 | 2006-12-28 | Miller Raanan A | Combined mass and differential mobility spectrometry and associated methods, systems, and devices |
| US7858927B2 (en) * | 2007-11-23 | 2010-12-28 | Dh Technologies Development Pte, Ltd. | Apparatus and method for operating a differential mobility analyzer with a mass spectrometer |
| US20120326023A1 (en) * | 2011-06-27 | 2012-12-27 | Department Of Homeland Security | ION MOBILITY SPECTROMETER to MASS SPECTROMETER INTERFACE |
| CN103367090A (en) * | 2012-03-30 | 2013-10-23 | 岛津分析技术研发（上海）有限公司 | An ion analyzer and an ion analysis method |
-
2013
- 2013-12-13 CN CN201310691002.5A patent/CN104716006A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060289745A1 (en) * | 2005-05-24 | 2006-12-28 | Miller Raanan A | Combined mass and differential mobility spectrometry and associated methods, systems, and devices |
| US7858927B2 (en) * | 2007-11-23 | 2010-12-28 | Dh Technologies Development Pte, Ltd. | Apparatus and method for operating a differential mobility analyzer with a mass spectrometer |
| US20120326023A1 (en) * | 2011-06-27 | 2012-12-27 | Department Of Homeland Security | ION MOBILITY SPECTROMETER to MASS SPECTROMETER INTERFACE |
| CN103367090A (en) * | 2012-03-30 | 2013-10-23 | 岛津分析技术研发（上海）有限公司 | An ion analyzer and an ion analysis method |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105513935A (en) * | 2016-01-13 | 2016-04-20 | 中国科学院上海有机化学研究所 | Quick ionizing method and device |
| CN106057628A (en) * | 2016-06-13 | 2016-10-26 | 塔里木大学 | Migration tube and ion mobility spectrometer with migration tube for axial focusing under atmospheric pressure |
| CN106057628B (en) * | 2016-06-13 | 2018-03-27 | 塔里木大学 | Axial focused ion mobility spectrometer under migration tube and atmospheric pressure with the migration tube |
| CN108335964A (en) * | 2017-01-20 | 2018-07-27 | 广州智纯科学仪器有限公司 | Ion mobility spectrometry and flight time mass spectrum combined instrument and its connecting interface structure |
| CN107275180A (en) * | 2017-06-29 | 2017-10-20 | 哈尔滨工业大学（威海） | Ion receiving pole |
| CN107275180B (en) * | 2017-06-29 | 2019-07-12 | 哈尔滨工业大学（威海） | Ion receiving pole |
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Application publication date: 20150617 |