CN106039193A - Traditional Chinese medicine preparation for treating oral aphthae in children - Google Patents

Traditional Chinese medicine preparation for treating oral aphthae in children Download PDF

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Publication number
CN106039193A
CN106039193A CN201610539391.3A CN201610539391A CN106039193A CN 106039193 A CN106039193 A CN 106039193A CN 201610539391 A CN201610539391 A CN 201610539391A CN 106039193 A CN106039193 A CN 106039193A
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parts
children
chinese medicine
preparation
oral aphthae
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刘兴涛
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9064Amomum, e.g. round cardamom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a traditional Chinese medicine preparation for treating the oral aphthae in children. The preparation is prepared from honeysuckles, round cardamom, herb of Slenderleaf Ixeris, coptidis rhizoma, radix angelicae sinensis, fructus mume, radix scutellariae, borneol, bamboo leaves, cortex cinnamomi and Trametes robiniophia Murr. The preparation can be directly smeared on a wound and achieves the effects on clearing away heat and fire, and eliminating inflammation and stopping pain after directly making contact with the wound. The preparation is simple in use method and has wide application prospects.

Description

A kind of Chinese medicine composition preparation treating oral aphthae in children
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine composition preparation treating oral aphthae in children.
Background technology
Oral ulcer is commonly called as " aphtha ", is a kind of common ulcerative damages disease betiding oral mucosa, and has There is the feature of periodical attack repeatedly, be difficult to radical cure.In general, aphtha be more common in inside lip, tongue, tongue abdomen, cheek mucosa, front The positions such as front yard ditch, soft palate, the mucosa at these positions lacks keratinization layer or keratinization is poor, is susceptible to single or multiple size The circle not waited or oval ulcer, surface covers greyish white or yellow pseudomembrane, concavity, clear border, surrounding mucosa red and Micro-swollen.Tongue ulcer refers to betide tongue, the oral ulcer of tongue abdominal part position.Sharp ache, locally causalgia during oral ulcer outbreak Substantially, severe patient also can affect diet, speak, and daily life causes very big inconvenience;Can concurrently halitosis, chronic pharyngitis, constipation, The General Symptomies such as headache, dizzy, nauseating, weak, irritated, heating, lymphadenectasis.The method existence for the treatment of aphtha at present takes effect Slowly the problem that drug effect can be gradually reduced is used and for a long time.
Summary of the invention
For the deficiencies in the prior art, the invention provides a kind of Chinese medicine composition preparation treating oral aphthae in children.
For achieving the above object, the present invention is achieved through the following technical solutions:
A kind of Chinese medicine composition preparation treating oral aphthae in children, is made up of the raw material of following weight portion: Flos Lonicerae 4-8 part, bean Cool 2-9 part, bud lettuce 5-9 part, Rhizoma Coptidis 8-15 part, Radix Angelicae Sinensis 12-16, Fructus Mume 3-10 part, Radix Scutellariae 3-6 part, Borneolum Syntheticum 8-15 part, Folium Bambusae 6- 10, Cortex Cinnamomi 1-4 part, Chinese scholartree pretty young woman's 5-15 part.
Preferably, it is made up of the raw material of following weight portion: Flos Lonicerae 5-7 part, Fructus Amomi Rotundus 3-7 part, bud lettuce 6-8 part, Rhizoma Coptidis 9- 11 parts, Radix Angelicae Sinensis 13-15, Fructus Mume 4-8 part, Radix Scutellariae 4-5 part, Borneolum Syntheticum 9-13 part, Folium Bambusae 7-9, Cortex Cinnamomi 2-3 part, Chinese scholartree pretty young woman's 6-12 part.
Preferably, it is made up of the raw material of following weight portion: Flos Lonicerae 6 parts, 5 parts of Fructus Amomi Rotundus, bud lettuce 8 parts, Rhizoma Coptidis 10 parts, Radix Angelicae Sinensis 15, Fructus Mume 5 parts, Radix Scutellariae 4 parts, Borneolum Syntheticum 10 parts, 7 parts of Folium Bambusae, Cortex Cinnamomi 3 parts, Chinese scholartree pretty young woman 10 parts.
Preparation process is as follows:
1) by Flos Lonicerae, bud lettuce, Radix Angelicae Sinensis, Radix Scutellariae, Folium Bambusae, Cortex Cinnamomi mixing, it is fully ground after sieving and obtains mixed-powder A also Being placed in hermetic container, the water soaking of addition A6-9 times of quality of mixed-powder 24-48 hour, then filter and remove residue, filtrate is standby;
2) Fructus Amomi Rotundus, Rhizoma Coptidis, Fructus Mume, Borneolum Syntheticum, Chinese scholartree pretty young woman are mixed and the driest, sieve after grinding and obtain mixture B;
3) by step 2) in gained mixture B add step 1) described filtrate is stirred and be dry, pulverize after cross 60-120 Mesh sieve, to obtain final product.
Preferably, described step 1) in add the water soaking 36 hours of 7 times of quality of mixed-powder.
Preferably, described step 3) in pulverize and sieve 60 mesh.
The invention provides a kind of Chinese medicine composition preparation treating oral aphthae in children, it provides the benefit that: the present invention passes through will Raw material of Chinese medicine composition is divided into two parts to carry out the mixing of solid-state and liquid, can effectively improve the mix homogeneously of Chinese medicine ingredients Property, Combination is preferable.Inside gained Chinese medicine of the present invention composition preparation special for treating children lip, inside cheek, on tongue, Sublingual occurs Oral ulcer, and can effectively eliminate brush teeth gargle, burning pain that the daily routines such as feed produce.Chinese medicine of the present invention forms Preparation can directly spread upon wound, and medicine directly acts on wound, reaches the effect of heat clearing away and internal heat reducing, reducing swelling and alleviating pain, and Can effectively suppress aphtha to recur, be with a wide range of applications.
Detailed description of the invention
For making the purpose of the embodiment of the present invention, technical scheme and advantage clearer, below in conjunction with the enforcement of the present invention Example, is clearly and completely described the technical scheme in the embodiment of the present invention.Based on the embodiment in the present invention, this area The every other embodiment that those of ordinary skill is obtained under not making creative work premise, broadly falls into present invention protection Scope.
Embodiment 1:
A kind of Chinese medicine composition preparation treating oral aphthae in children, is made up of the raw material of following weight portion: Flos Lonicerae 6 parts, Fructus Amomi Rotundus 5 Part, bud lettuce 8 parts, Rhizoma Coptidis 10 parts, Radix Angelicae Sinensis 15 parts, Fructus Mume 5 parts, Radix Scutellariae 4 parts, Borneolum Syntheticum 10 parts, 7 parts of Folium Bambusae, Cortex Cinnamomi 3 parts, Chinese scholartree pretty young woman 10 Part.
Preparation process is as follows:
1) by Flos Lonicerae, bud lettuce, Radix Angelicae Sinensis, Radix Scutellariae, Folium Bambusae, Cortex Cinnamomi mixing, it is fully ground after sieving and obtains mixed-powder A also Being placed in hermetic container, the water soaking of addition A7 times of quality of mixed-powder 36 hours, then filter and remove residue, filtrate is standby;
2) Fructus Amomi Rotundus, Rhizoma Coptidis, Fructus Mume, Borneolum Syntheticum, Chinese scholartree pretty young woman are mixed and the driest, sieve after grinding and obtain mixture B;
3) by step 2) in gained mixture B add step 1) described filtrate is stirred and be dry, pulverize after cross 60 mesh sieves, Obtain.
Embodiment 2:
A kind of Chinese medicine composition preparation treating oral aphthae in children, is made up of the raw material of following weight portion: Flos Lonicerae 4 parts, Fructus Amomi Rotundus 8 Part, bud lettuce 6 parts, Rhizoma Coptidis 13 parts, Radix Angelicae Sinensis 12 parts, Fructus Mume 10 parts, Radix Scutellariae 3 parts, Borneolum Syntheticum 15 parts, 6 parts of Folium Bambusae, Cortex Cinnamomi 3 parts, Chinese scholartree pretty young woman 15 Part.
Preparation process is as follows:
1) by Flos Lonicerae, bud lettuce, Radix Angelicae Sinensis, Radix Scutellariae, Folium Bambusae, Cortex Cinnamomi mixing, it is fully ground after sieving and obtains mixed-powder A also Being placed in hermetic container, the water soaking of addition A6 times of quality of mixed-powder 24 hours, then filter and remove residue, filtrate is standby;
2) Fructus Amomi Rotundus, Rhizoma Coptidis, Fructus Mume, Borneolum Syntheticum, Chinese scholartree pretty young woman are mixed and the driest, sieve after grinding and obtain mixture B;
3) by step 2) in gained mixture B add step 1) described filtrate is stirred and be dry, pulverize after cross 100 mesh Sieve, to obtain final product.
Embodiment 3:
A kind of Chinese medicine composition preparation treating oral aphthae in children, is made up of the raw material of following weight portion: Flos Lonicerae 7 parts, Fructus Amomi Rotundus 4 Part, bud lettuce 7 parts, Rhizoma Coptidis 9 parts, Radix Angelicae Sinensis 16 parts, Fructus Mume 7 parts, Radix Scutellariae 5 parts, Borneolum Syntheticum 8 parts, 10 parts of Folium Bambusae, Cortex Cinnamomi 1 part, Chinese scholartree pretty young woman 8 parts.
Preparation process is as follows:
1) by Flos Lonicerae, bud lettuce, Radix Angelicae Sinensis, Radix Scutellariae, Folium Bambusae, Cortex Cinnamomi mixing, it is fully ground after sieving and obtains mixed-powder A also Being placed in hermetic container, the water soaking of addition A8 times of quality of mixed-powder 40 hours, then filter and remove residue, filtrate is standby;
2) Fructus Amomi Rotundus, Rhizoma Coptidis, Fructus Mume, Borneolum Syntheticum, Chinese scholartree pretty young woman are mixed and the driest, sieve after grinding and obtain mixture B;
3) by step 2) in gained mixture B add step 1) described filtrate is stirred and be dry, pulverize after cross 120 mesh Sieve, to obtain final product.
Embodiment 4:
A kind of Chinese medicine composition preparation treating oral aphthae in children, is made up of the raw material of following weight portion: Flos Lonicerae 8 parts, Fructus Amomi Rotundus 2 Part, bud lettuce 5 parts, Rhizoma Coptidis 11 parts, Radix Angelicae Sinensis 14, Fructus Mume 3 parts, Radix Scutellariae 6 parts, Borneolum Syntheticum 8 parts, 10 parts of Folium Bambusae, Cortex Cinnamomi 4 parts, Chinese scholartree pretty young woman 9 parts.
Preparation process is as follows:
1) by Flos Lonicerae, bud lettuce, Radix Angelicae Sinensis, Radix Scutellariae, Folium Bambusae, Cortex Cinnamomi mixing, it is fully ground after sieving and obtains mixed-powder A also Being placed in hermetic container, the water soaking of addition A9 times of quality of mixed-powder 30 hours, then filter and remove residue, filtrate is standby;
2) Fructus Amomi Rotundus, Rhizoma Coptidis, Fructus Mume, Borneolum Syntheticum, Chinese scholartree pretty young woman are mixed and the driest, sieve after grinding and obtain mixture B;
3) by step 2) in gained mixture B add step 1) described filtrate is stirred and be dry, pulverize after cross 80 mesh sieves, Obtain.
Clinical experiment is observed:
1) Therapeutic Method:
Clinic of the present invention accepts 50 4-8 year oral aphthae in children patients for medical treatment.Wherein, 22 examples are inside lip, in 18 examples are cheek Side, 10 examples are the big ulcer of Semen Glycines that white yellow occurs in tongue different parts.
2) therapeutic outcome
Patient uses the aphtha Chinese medicine composition preparation in above-described embodiment 1, sooner or later respectively smears once every day, and symptom is lighter Smearing three to four times can fully recover, what symptom was heavier smears continuously one week and can fully recover, and cure rate is up to 99%, and effect is notable.
Above example only in order to technical scheme to be described, is not intended to limit;Although with reference to previous embodiment The present invention is described in detail, it will be understood by those within the art that: it still can be to aforementioned each enforcement Technical scheme described in example is modified, or wherein portion of techniques feature is carried out equivalent;And these amendment or Replace, do not make the essence of appropriate technical solution depart from the spirit and scope of various embodiments of the present invention technical scheme.

Claims (6)

1. the Chinese medicine composition preparation treating oral aphthae in children, it is characterised in that be made up of the raw material of following weight portion: Flos Lonicerae 4-8 part, Fructus Amomi Rotundus 2-9 part, bud lettuce 5-9 part, Rhizoma Coptidis 8-15 part, Radix Angelicae Sinensis 12-16, Fructus Mume 3-10 part, Radix Scutellariae 3-6 part, Borneolum Syntheticum 8-15 Part, Folium Bambusae 6-10 part, Cortex Cinnamomi 1-4 part, Chinese scholartree pretty young woman's 5-15 part.
2. form preparation according to the Chinese medicine treating oral aphthae in children described in claim 1, it is characterised in that by following weight portion Raw material forms: Flos Lonicerae 5-7 part, Fructus Amomi Rotundus 3-7 part, bud lettuce 6-8 part, Rhizoma Coptidis 9-11 part, Radix Angelicae Sinensis 13-15, Fructus Mume 4-8 part, Radix Scutellariae 4-5 part, Borneolum Syntheticum 9-13 part, Folium Bambusae 7-9 part, Cortex Cinnamomi 2-3 part, Chinese scholartree pretty young woman's 6-12 part.
3. form preparation according to the Chinese medicine treating oral aphthae in children described in claim 2, it is characterised in that by following weight portion Raw material forms: Flos Lonicerae 6 parts, 5 parts of Fructus Amomi Rotundus, bud lettuce 8 parts, Rhizoma Coptidis 10 parts, Radix Angelicae Sinensis 15 parts, Fructus Mume 5 parts, Radix Scutellariae 4 parts, Borneolum Syntheticum 10 Part, 7 parts of Folium Bambusae, Cortex Cinnamomi 3 parts, Chinese scholartree pretty young woman 10 parts.
Treat the preparation method of the Chinese medicine composition preparation of oral aphthae in children the most according to claim 3, it is characterised in that described system Standby step is as follows:
1) by Flos Lonicerae, bud lettuce, Radix Angelicae Sinensis, Radix Scutellariae, Folium Bambusae, Cortex Cinnamomi mixing, it is fully ground after sieving and obtains mixed-powder A and be placed in In hermetic container, the water soaking of addition A6-9 times of quality of mixed-powder 24-48 hour, then filter and remove residue, filtrate is standby;
2) Fructus Amomi Rotundus, Rhizoma Coptidis, Fructus Mume, Borneolum Syntheticum, Chinese scholartree pretty young woman are mixed and the driest, sieve after grinding and obtain mixture B;
3) by step 2) mixture B add step 1) filtrate in, after stirring and dry, pulverize cross 60-120 mesh sieve, to obtain final product.
Treat the preparation method of the Chinese medicine composition preparation of oral aphthae in children the most according to claim 4, it is characterised in that described step Rapid 1) water soaking of addition 7 times of quality of mixed-powder 36 hours in.
Treat the preparation method of the Chinese medicine composition preparation of oral aphthae in children the most according to claim 4, it is characterised in that described step Rapid 3) 60 mesh are pulverized and sieved in.
CN201610539391.3A 2016-07-08 2016-07-08 Traditional Chinese medicine preparation for treating oral aphthae in children Pending CN106039193A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104173779A (en) * 2013-05-21 2014-12-03 柳景朋 Traditional Chinese medicine composition for treating oral ulcer
CN104324098A (en) * 2014-11-19 2015-02-04 天津太平洋制药有限公司 Traditional Chinese medicine for treating aphtha
CN104491551A (en) * 2015-01-04 2015-04-08 霍山县中医院 Traditional Chinese medicine for treating aphtha

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104173779A (en) * 2013-05-21 2014-12-03 柳景朋 Traditional Chinese medicine composition for treating oral ulcer
CN104324098A (en) * 2014-11-19 2015-02-04 天津太平洋制药有限公司 Traditional Chinese medicine for treating aphtha
CN104491551A (en) * 2015-01-04 2015-04-08 霍山县中医院 Traditional Chinese medicine for treating aphtha

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
穆天军: "口疡散治疗口腔溃疡", 《甘肃中医》 *

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