CN106038843A - Traditional Chinese medicine preparation for treating polymyalgia rheumatica and preparation method thereof - Google Patents
Traditional Chinese medicine preparation for treating polymyalgia rheumatica and preparation method thereof Download PDFInfo
- Publication number
- CN106038843A CN106038843A CN201610473113.2A CN201610473113A CN106038843A CN 106038843 A CN106038843 A CN 106038843A CN 201610473113 A CN201610473113 A CN 201610473113A CN 106038843 A CN106038843 A CN 106038843A
- Authority
- CN
- China
- Prior art keywords
- medicine preparation
- chinese medicine
- polymyalgia rheumatica
- traditional chinese
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/09—Lichens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/238—Saposhnikovia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/59—Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/754—Evodia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/85—Verbenaceae (Verbena family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses a traditional Chinese medicine preparation for treating polymyalgia rheumatica and a preparation method thereof, and belongs to the field of traditional Chinese medicines. The effective ingredient of the traditional Chinese medicine preparation is prepared from the following raw materials: rhizoma atractylodis macrocephalae, hempleaf negundo chastetree leaves, cassia twigs, kudzu vine roots, ligusticum wallichii, scutellaria indica, sassafras tsumu, passiflora wilsonii, flat-stemmed tetrastigma, trichosanthes palmata, azoila imbricata, parmelia tinctourium, pinus tabulaeformis, rodgersia sambucifolia hemsl, saposhnicovia divaricata and urena lobata. The traditional Chinese medicine preparation is prepared from traditional Chinese medicinal materials with effects of clearing heat, removing toxicity, expelling the evils in muscles by means of diaphoresis, dispelling wind, drying dampness and relieving pain, has the effects of relaxing tendons, activating collaterals, promoting circulation of blood and qi, warmly invigorating pulse-beat, removing stasis and diminishing swelling, is convenient to use, and has good absorption effect and no adverse, toxic or side effect. Clinical application verifies that the traditional Chinese medicine preparation has an extremely good effect for relieving and treating polymyalgia rheumatica, and is applicable to clinical treating and nursing popularization and application of polymyalgia rheumatica.
Description
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of Chinese medicine preparation treating polymyalgia rheumatica and preparation method.
Background technology
Polymyalgia rheumatica (PMR) be a kind of with extremity and trunk near-end myalgia the clinical syndrome as feature, right
Low-dose glucocorticoids reaction sensitivity.Often show as in neck, pectoral girdle and pelvic girdle flesh 2 or 2 with the pain of upper bit and
Stiff, continue 30 minutes or the longer time, no less than one-month period, the age is more than 50 years old.
The clinical manifestation of polymyalgia rheumatica is:
1, General Symptoms: patients more than half have General Symptoms, such as tired, low grade fever, loses weight, and possibly as starting
Symptom.Seldom there is peak heat in the PMR patient of nonjoinder giant cell arteritis (GCA).
2, near-end osteoarticular myalgia and morning are stiff: polymyalgia rheumatica is with symmetric proximal joint and muscle
Pain is ached and deadlock in morning is characterized, and the most prominent with shoulder joint, neck and pelvic girdle muscle, the most symmetrically property is remote when being distributed
Also can get involved in end muscle group and joint.Patient's pectoral girdle pain of more than 70% occurs at first, then develop into extremity near-end,
The positions such as neck, breast, buttocks, directly affect the life of patient, and above-mentioned symptom can onset suddenly, it is possible to concealment onset, continued for several weeks
To the several months.Pain and deadlock in morning in the morning and movable time increase the weight of, above-mentioned symptom may be heavier and make patient's daily routines limited,
So that can not stand up and deeply breathe.Touching a tender spot can occur in muscle, and affects activity and causes disuse atrophy, and being likely to occur muscle
Contracture.Muscular strength is the most normal.
3, joint symptoms: the arthropathy of polymyalgia rheumatica mainly shows as tendinitis and synovitis.Polycentric grind
Studying carefully display, the synovitis of the light moderate of PMR mainly affects proximal joint, spinal column and limbs band, as shoulder joint is the most often got involved；Separately have
15%～50% there is periphery articular synovitis, the most common with knee joint and carpal joint.
The physical examination positive sign of polymyalgia rheumatica is less, can have an anemia, shoulder and knee joint mild tenderness, swollen
Swollen or a little synovial membrane hydrops is levied.Breast lock, shoulder, marrow bone joint biopsies show as non-specific lymphatic synovitis.Non-steroidal
AID can alleviate partial symptoms.Low dose of glucocorticoid can receive good efficacy, can make skeletal musculature pain and
Stiff symptom obtains and significantly improves, but can not effect a radical cure, recurrent exerbation, ultimately results in deterioration, brings great pain to patient
Bitter；And Chinese materia medica is as the traditional medicine of China, there is the advantages such as effect strong, instant effect, lasting medicine, and do not have dependency,
Drug resistance and toxic and side effects, therefore select a kind of Chinese medicine preparation treatment polymyalgia rheumatica, for treatment polymyalgia rheumatica
There is highly important clinical meaning.
Summary of the invention
The invention provides a kind of Chinese medicine preparation for treating polymyalgia rheumatica and preparation method, the present invention is selected clearly
Thermal detoxification, diaphoresis expelling pathogenic factors from muscles, removing dampness of dispeling the wind, the Chinese crude drug prescription of removing damp and stopping pain are concocted, and have relaxing muscles and tendons and activating QI and blood in the collateral, blood-activating and qi-promoting, temperature to stimulate the menstrual flow
Arteries and veins, effect of dissipating blood stasis for subsidence of swelling, easy to use, good absorbing effect is without bad and toxic and side effects, according to clinical verification, many to rheumatic
Myalgia has fabulous alleviation and therapeutic effect, is suitable to clinical treatment and the nursing popularization and application of polymyalgia rheumatica.
For achieving the above object, technical scheme is implemented as follows:
A kind of Chinese medicine preparation treating polymyalgia rheumatica, makes raw material composition and the weight of described Chinese medicine preparation effective ingredient
Amount number is:
Make described Chinese medicine preparation effective ingredient raw material composition and parts by weight be:
Make described Chinese medicine preparation effective ingredient raw material composition and parts by weight be:
Make described Chinese medicine preparation effective ingredient raw material composition and parts by weight be:
The preparation method of a kind of Chinese medicine preparation treating polymyalgia rheumatica, comprises the following steps that:
(1) Rhizoma Atractylodis macrocephalae, Radix Puerariae, Rhizoma Chuanxiong, Caulis et Radix Tetrastigmatis Planicaulis and Radix Stephaniae Cepharanthae are gone the removal of impurity, clean, be placed in container, add yellow wine stirring
Uniformly, take out after being run through by yellow wine and dry, grind into powder in being placed in mortar, obtained the fine powder of 120 mesh, standby；
(2) Folium Viticis Negundo, Herba Passiflorae Wilsonii, Parmelia saxatilis Ach. and Radix Urenae Lobatae are gone the removal of impurity, clean, fry in being placed in pot and be advisable to tack-free,
Taking-up is dried, and grinds into powder in being placed in mortar, obtains the fine powder of 140 mesh, standby；
(3) Ramulus Cinnamomi, Herba azollae imbricatae, Lignum Pini Nodi, Rhizoma Rodgersiae and Radix Saposhnikoviae are gone the removal of impurity, clean and put in container, add 8～10 times amount
Distilled water, after soaking 5～7 hours, boils 3～4 hours, extracts；Again add 6～8 times amount distilled water, boil 1～3 hour,
Extract；Finally, add 4～6 times amount distilled water, heated and boiled 1～2 hours, extract；Merge three extracting solution, filter, obtain filter
Liquid, being condensed into relative density at 60 DEG C is the thick paste of 1.10～1.13, dries, standby；
(4) Herba Scutellariae indicae and wiping tree are gone the removal of impurity, clean, microwave drying, grind into powder in being placed in mortar, obtained 160 purposes
Fine powder, standby；
(5) glue is made after step (1), step (2), the fine powder of step (4) gained being mixed with the thick paste of step (3) gained
Capsule, is the Chinese medicine preparation of described treatment polymyalgia rheumatica.
The property of medicine of Chinese medicine used by the present invention is as follows:
Rhizoma Atractylodis macrocephalae: acrid in the mouth, hardship, cool in nature；Return liver, kidney channel.Blood-activating and qi-promoting, eliminating stasis to stop pain.For the thoracic obstruction, treating swelling and pain by traumatic injury, fracture
Sprain, rheumatic arthralgia, wait pain, venom." Luchuan book on Chinese herbal medicine " carries: " refute bone, detumescence, pain relieving.Control traumatic injury to swell and ache, fracture,
Rheumatic ostalgia.”
Folium Viticis Negundo: mildly bitter flavor, pungent, property is put down；Return lung meridian.Expelling pathogenic wind from the body surface, dehumidify parasite killing, pain relieving.For anemofrigid cold, eruptive disease
Stomachache is vomited and diarrhoea, dysentery, rheumatalgia, tinea pedis erysipelas, carbuncle tinea pedis." Fujian Chinese herbal medicine " carries: " expelling pathogenic wind from the body surface, regulating QI stomach function regulating.”
Ramulus Cinnamomi: sweet in the mouth, pungent, warm in nature；GUIXIN, lung, bladder warp.Diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.
For anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention edema, cardiopalmus renal mass." book on Chinese herbal medicine is the newest " carries: " warming middle-JIAO
Promoting the circulation of blood, spleen and stomach dry, dampness removing of subsiding a swelling.Control feel cold work fiber crops, muscle of brothers and take out pain, and the disease such as diseases caused by exogenous pathogenic factor are cold and cool.”
Radix Puerariae: sweet in the mouth, pungent, cool in nature；Return spleen, stomach warp.Expelling pathogenic factors from muscles for reducing heat, rash of promoting the production of body fluid, yang invigorating antidiarrheal.For fever caused by exogenous pathogens head
Bitterly, stiff nape and back, thirsty to quench one's thirst, measles without adequate eruption, hematodiarrhoea has loose bowels, hypertension, neck pain." not Lu " carries: " excessive cold invading middle-JIAO(the spleen and stomach) public attention of curing the wound
Bitterly, expelling pathogenic factors from muscles, deliver, perspire, loosing the interspaces of skin and muscles.Treat incised wound, pain relieving, side of body wind pain.Taking root juice, treatment is quenched one's thirst, typhoid fever high fever.”
Rhizoma Chuanxiong: acrid in the mouth, warm in nature.Return liver, gallbladder, pericardium channel.Blood-activating and qi-promoting, wind-expelling pain-stopping.For menoxenia, amenorrhea pain
Warp, lump in the abdomen stomachache, breast side of body twinge, tumbling and swelling, headache, rheumatic arthralgia." medicine origin " carries: " enriches blood, controls headache due to deficiency of blood.”
Herba Scutellariae indicae: acrid in the mouth, hardship, property is put down；GUIXIN, liver, lung meridian.Expelling wind and activating blood circulation, pain relieving of detoxifying.For traumatic injury, spit blood
Hemoptysis, carbuncle furunculosis, acute throat trouble is had a toothache." Quanzhou book on Chinese herbal medicine " carries: " heat-clearing and toxic substances removing, detumescence moves back Huang, by blood removing blood stasis with potent drugs, removing pus and relieving carbuncle, removing heat from blood
Hemostasis, throat.Curing mainly all larynxs Huang, also control lung-fire height dyspnea of heat type and cough, spit blood, hemoptysis is spat blood, and blood stasis is had a pain, and knife injury is hemorrhage, dislikes
Carbuncle sore swells, tiger, lyssodexis.”
Wipe tree: sweet in the mouth, light, warm in nature.Dispel the wind by wet, promoting blood circulation to remove blood stasis.For rheumatic arthritis, rheumatoid arthritis, waist
Muscular strain, chronic lambago and skelalgia, hemiplegia, traumatic injury, bruise is hemorrhage on cutter." register planted by Guangxi medicine " carries: " root: control stomach
Disease, rheumatism, hemiplegia.Stem and leaf dispels the wind, and dries, and controls edema, arthritis.”
Herba Passiflorae Wilsonii: mildly bitter flavor, warm in nature.Relaxing muscles and tendons to promote blood circulation, removing dampness and killing parasites.For rheumatic arthritis, injury and bone fracture, hepatitis malaria
Disease, ascariasis." choosing of Yunnan Chinese herbal medicine " carries: " dampness, hemostasis, antiinflammatory, granulation promoting.Dispelling the wind and dampness pathogens lumbago, hepatitis, liver cirrhosis, tumor,
Traumatic injury, fracture.”
Caulis et Radix Tetrastigmatis Planicaulis: puckery, acid, property is put down；GUIXIN, Liver Channel.Dispel the wind removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral.For rheumatic arthralgia, lumbar muscle strain,
Apoplectic hemiplegia, traumatic injury." conventional Chinese herbal medicine handbook " carries: " dispeiling pathogenic wind and removing dampness.Treating rheumatic lumbago and skelalgia, hemiplegia, muscle wind
Wet pain.”
Radix Stephaniae Cepharanthae: bitter in the mouth, pungent, cool in nature；Return spleen, lung, kidney channel.Heat-clearing and toxic substances removing, cooling blood for hemostasis, dissipating blood stasis for subsidence of swelling.For acute
Hepatitis, bacillary dysentery, acute appendicitis, stomachache, internal hemorrhage, traumatic injury, venom, mumps, lymph node
Inflammation, neurodermatitis." conventional Chinese herbal medicine handbook " carries: " dispel the wind, diuretic, heat clearing away, reduce phlegm.Dispelling the wind and dampness pathogens pain, lumbar muscle strain, kidney
Scorching edema, stomachache, pulmonary tuberculosis, innominate toxic swelling, venom.”
Herba azollae imbricatae: acrid in the mouth, cold in nature.Diaphoresis, dispels the wind, rash.For rheumatalgia, wind scabies urticaria, measles can not send out thoroughly, tinea
Skin ulcer burn." Traditional Chinese Medicine in Sichuan will " carries: " diaphoresis diuretic, expelling wind and dampness control sudden high fever itching over the body, diuresis；Only quenching one's thirst, dispelling the wind and dampness pathogens is stupid
Tinea.”
Parmelia saxatilis Ach.: sweet in the mouth, property is put down.Nourishing blood for improving eyesight, the kidney invigorating diuresis, heat-clearing and toxic substances removing.For blurred vision, haematemesis metrorrhagia, waist knee joint
Pain, urine burning pain, nebulousurine leucorrhea, burn." Shandong Chinese herbal medicine handbook " carries: " the kidney invigorating, strengthening bone and muscle.”
Lignum Pini Nodi: acrid in the mouth, hardship, warm in nature.Expelling wind and removing dampness, activating collaterals to relieve pain.For rheumatic arthritis, lumbago and skelalgia, Kaschin-Beck disease, fall
Beat and swell and ache." the southern regions of the Yunnan Province book on Chinese herbal medicine " carries: " wind-damp dispelling, promoting blood circulation to remove obstruction in the collateral, anti-inflammatory analgesic.Treating rheumatic arthritis, bones and muscles pain, hypertension
Caused hemiplegia, osteomyelitis, bone tuberculosis is passed through network, controls phlegm-fire, bones and muscles pain, and arthralgia chiefly caused by damp pathogen flaccidity is soft, bone and muscle strengthening.”
Rhizoma Rodgersiae: bitter in the mouth, puckery, cool in nature.Clearing away heat and cooling blood, menstruction regulating and pain relieving.For enteritis and dysentery, dysmenorrhea, menorrhagia, rheumatic
Arthritis, traumatic injury, traumatic hemorrhage, eczema scrotum." choosing of Yunnan Chinese herbal medicine " carries: " antiinflammatory, convergence, alunite of dispeling the wind, pain relieving.Control
Knife injury is hemorrhage, traumatic injury, rheumatic arthritis, dysentery, diarrhoea.”
Radix Saposhnikoviae: acrid in the mouth, sweet, warm in nature；Return bladder, liver, spleen channel.Deliver and dispel the wind, removing dampness to relieve pain.For affection of exogenous wind-cold, headache
Dizzy, stiffness of the nape, anemofrigid-damp arthralgia, joint aches, and extremity contraction is anxious, tetanus." Changsha medicine solution " carries: " network of passing through, by wet excessive, clearance
Joint, relieve the pain pain, and relaxing muscles and tendons arteries and veins stretches anxious contraction, and podomere of living plays paralysis, holds back spontaneous perspiration, helmet antiperspirant, breaks, metrorrhagia.”
Radix Urenae Lobatae: sweet in the mouth, light, cool in nature；Return lung, spleen channel.Expelling wind and activating blood circulation, clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling.For Fengshi Guanjie
Bitterly, malaria of catching a cold, enteritis and dysentery, infantile dyspepsia, leucorrhea." east, Fujian book on Chinese herbal medicine " carries: " control stiffness of the muscle and joint, rheumatic arthralgia, yang deficiency
Spontaneous perspiration, edema, have loose bowels, puerperal exposure to wind, leukorrhagia, stomachache.”
The present invention compared with prior art, has the advantages that
The selected heat-clearing and toxic substances removing of the present invention, diaphoresis expelling pathogenic factors from muscles, removing dampness of dispeling the wind, the Chinese crude drug prescription of removing damp and stopping pain are concocted, and have relaxing muscles and tendons
Active, effect of blood-activating and qi-promoting, promoting the flow of QI-blood by warming the meridian, dissipating blood stasis for subsidence of swelling, easy to use, good absorbing effect, without bad and toxic and side effects, warp
Clinical verification, has fabulous alleviation and therapeutic effect to polymyalgia rheumatica, is suitable to the clinical treatment of polymyalgia rheumatica and protects
Reason popularization and application.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
The processing step of Chinese medicine preparation preparation method of the present invention is:
(1) Rhizoma Atractylodis macrocephalae, Radix Puerariae, Rhizoma Chuanxiong, Caulis et Radix Tetrastigmatis Planicaulis and Radix Stephaniae Cepharanthae are gone the removal of impurity, clean, be placed in container, add yellow wine stirring
Uniformly, take out after being run through by yellow wine and dry, grind into powder in being placed in mortar, obtained the fine powder of 120 mesh, standby；
(2) Folium Viticis Negundo, Herba Passiflorae Wilsonii, Parmelia saxatilis Ach. and Radix Urenae Lobatae are gone the removal of impurity, clean, fry in being placed in pot and be advisable to tack-free,
Taking-up is dried, and grinds into powder in being placed in mortar, obtains the fine powder of 140 mesh, standby；
(3) Ramulus Cinnamomi, Herba azollae imbricatae, Lignum Pini Nodi, Rhizoma Rodgersiae and Radix Saposhnikoviae are gone the removal of impurity, clean and put in container, add 8～10 times amount
Distilled water, after soaking 5～7 hours, boils 3～4 hours, extracts；Again add 6～8 times amount distilled water, boil 1～3 hour,
Extract；Finally, add 4～6 times amount distilled water, heated and boiled 1～2 hours, extract；Merge three extracting solution, filter, obtain filter
Liquid, being condensed into relative density at 60 DEG C is the thick paste of 1.10～1.13, dries, standby；
(4) Herba Scutellariae indicae and wiping tree are gone the removal of impurity, clean, microwave drying, grind into powder in being placed in mortar, obtained 160 purposes
Fine powder, standby；
(5) glue is made after step (1), step (2), the fine powder of step (4) gained being mixed with the thick paste of step (3) gained
Capsule, is the Chinese medicine preparation of described treatment polymyalgia rheumatica.
Usage and dosage: oral, three times a day, the morning, noon and afternoon, the most each 2,10 days be a course for the treatment of, usual 2～3
The onset recovery from illness course for the treatment of, pertinacious disease needs 4～5 recoveries from illness course for the treatment of.
Embodiment 2
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage are same as in Example 1.
Embodiment 3
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage are same as in Example 1.
Embodiment 4
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage are same as in Example 1.
Clinical data:
1, case selection:
Selecting the polymyalgia rheumatica 408 example clinical observation that my institute or outer court make a definite diagnosis, patient is randomly divided into two groups, treatment group
204 examples, wherein male 70 example, women 134 example, age 50～79 years old, 63 years old mean age, the course of disease 3 months～5 years, average 3
Year.Matched group 204 example, wherein male 77 example, women 127 example, age 50～80 years old, 60 years old mean age, the course of disease 1 month～4
Year, average 2 years.The course of disease of two groups of cases, degrees of symptoms are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes Chinese medicine preparation of the present invention, and oral, three times a day, the morning, noon and afternoon the most once, each 2,10 days are one
The course for the treatment of, usual 2～3 the onset recoveries from illness course for the treatment of, pertinacious disease needs 4～5 recoveries from illness course for the treatment of.
Matched group takes methylprednisolone sheet, oral, and 1 day 16～24mg divide 2 times, maintenance dose 1 day 4～8mg.
3, efficacy determination:
(1) cure: the transference cures such as the pain such as pectoral girdle, pelvis joint, cervical region are stiff for morning, limitation of activity；Healthy, movable
Freely.
(2) effective: above-mentioned symptom has been alleviated, healthy, and activity is freely.
(3) invalid: disease is unchanged.
4, result:
Take in the treatment group of Chinese medicine preparation of the present invention, cure 164 examples, effective 25 examples, invalid 15 examples, cure rate
80.4%, total effective rate 92.6%.
Matched group is cured 138 examples, effective 31 examples, invalid 35 examples, cure rate 67.6%, total effective rate 82.8%.
Result above shows, treatment group cure rate and total effective rate are apparently higher than matched group.
1, clock ××, man, 50 years old, Production Supervisor, Bay, Ningde, Fujian Province people.Patient has under low grade fever, weak, asthenia, body weight at the initial stage
Degradation General Symptoms, is paid attention to, later stage neck, pectoral girdle near-end muscular soreness, stiff discomfort.Once various analgesic was taken
Thing, effect is the most inconspicuous, and my institute checked later, was diagnosed as polymyalgia rheumatica.Take 1 course for the treatment of of Chinese medicine preparation of the present invention
After, above symptom is substantially alleviated, and after continuing to take 1 course for the treatment of, above transference cure, livelihood restoration is normal, and activity is freely.Follow up a case by regular visits to
So far do not recur.
2, ×× slowly, female, 54 years old, peasant, people from Linyi, Shandong.Patient's pectoral girdle, pelvic girdle near-end muscle deadlock pain, with daystart
Time movable obvious, systemic pain of especially waking up morning is stiff unbearably, combs one's hair, clothing, stair activity is all had any problem time serious.By me
Institute is diagnosed as polymyalgia rheumatica.After taking 2 courses for the treatment of of Chinese medicine preparation of the present invention, pectoral girdle, pelvic pain substantially alleviate, and live
Dynamic improvement, continues to strengthen after taking 2 courses for the treatment of, and pain and stiff sense disappear, and movable recovery is normal.Follow up a case by regular visits to not recur so far.
3, high ××, female, 59 years old, sanitationman, people from Xinyu, Jiangxi.The unexpected onset of patient, daystart is waken up and shoulder back is occurred
Etc. symptoms such as systemic pain and low grade fever, weak, take for overworking caused, alleviated after taking tablet for alleviating pain, but in the recent period
Feels pain increases the weight of earlier above, and limitation of activity.The most to our hospital, it is diagnosed as polymyalgia rheumatica.Take Chinese medicine of the present invention
After 2 courses for the treatment of of preparation, symptom takes a turn for the better, after continuing to take 3 courses for the treatment of, transference cure, activity freely, not recurrence.
4, ×× is opened, man, 62 years old, unemployed, Zhejiang Jiaxing people.Patient suffers from the polymyalgia rheumatica several months, fails to fully recover from an illness always
And neck, pectoral girdle muscle group rest pain are stiff more,.After people recommends to take 3 courses for the treatment of of Chinese medicine preparation of the present invention, symptom is complete
Disappearing, freely, livelihood restoration is normal in activity.Follow up a case by regular visits to not recur so far.
5, Pueraria lobota ××, female, 66 years old, retired professor, people from Shijiazhuang, Hebei.Patient's shoulder joint, neck and pelvic girdle myalgia
Pain is prominent, after develop into the positions such as extremity near-end, neck, breast, buttocks, directly affect the life of patient.It is diagnosed as rheumatic by my institute
Myalgia.After taking 3 courses for the treatment of of Chinese medicine preparation of the present invention, symptom takes a turn for the better, and after continuing to take 1 course for the treatment of, pain symptom disappears, and lives
Move freely, not recurrence.
6, Cui's ××, man, 74 years old, unemployed, people from Datong.Patient suffers from rheumatic myalgia for many years, has a strong impact on life
Live, amyotrophy, red and swollen heat, the most painful.After people recommends to take 3 courses for the treatment of of Chinese medicine preparation of the present invention, symptom substantially alleviates, and continues
Continuing after taking 2 courses for the treatment of, physical recovery is normal, and activity freely, is not recurred so far.
Claims (5)
1. the Chinese medicine preparation treating polymyalgia rheumatica, it is characterised in that: make the former of described Chinese medicine preparation effective ingredient
Material forms and parts by weight are:
A kind of Chinese medicine preparation treating polymyalgia rheumatica the most according to claim 1, it is characterised in that: make described in
The raw material of medicine preparation effective ingredient forms and parts by weight are:
A kind of Chinese medicine preparation treating polymyalgia rheumatica the most according to claim 1, it is characterised in that: make described in
The raw material of medicine preparation effective ingredient forms and parts by weight are:
A kind of Chinese medicine preparation treating polymyalgia rheumatica the most according to claim 1, it is characterised in that: make described in
The raw material of medicine preparation effective ingredient forms and parts by weight are:
5. a preparation method for the Chinese medicine preparation of the treatment polymyalgia rheumatica as described in any one of Claims 1 to 4, it is special
Levy and be: comprise the following steps that:
(1) Rhizoma Atractylodis macrocephalae, Radix Puerariae, Rhizoma Chuanxiong, Caulis et Radix Tetrastigmatis Planicaulis and Radix Stephaniae Cepharanthae are gone the removal of impurity, clean, be placed in container, add yellow wine stirring all
Even, take out after being run through by yellow wine and dry, grind into powder in being placed in mortar, obtained the fine powder of 120 mesh, standby；
(2) Folium Viticis Negundo, Herba Passiflorae Wilsonii, Parmelia saxatilis Ach. and Radix Urenae Lobatae are gone the removal of impurity, clean, fry in being placed in pot and be advisable to tack-free, take out
Dry, grind into powder in being placed in mortar, obtained the fine powder of 140 mesh, standby；
(3) Ramulus Cinnamomi, Herba azollae imbricatae, Lignum Pini Nodi, Rhizoma Rodgersiae and Radix Saposhnikoviae are gone the removal of impurity, clean and put in container, add the distillation of 8～10 times amount
Water, after soaking 5～7 hours, boils 3～4 hours, extracts；Again add 6～8 times amount distilled water, boil 1～3 hour, extract；
Finally, add 4～6 times amount distilled water, heated and boiled 1～2 hours, extract；Merge three extracting solution, filter, obtain filtrate, concentrate
At becoming 60 DEG C, relative density is the thick paste of 1.10～1.13, dries, standby；
(4) Herba Scutellariae indicae and wiping tree are gone the removal of impurity, clean, microwave drying, grind into powder in being placed in mortar, obtained the fine powder of 160 mesh,
Standby；
(5) capsule is made after step (1), step (2), the fine powder of step (4) gained being mixed with the thick paste of step (3) gained,
It is the Chinese medicine preparation of described treatment polymyalgia rheumatica.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610473113.2A CN106038843A (en) | 2016-06-17 | 2016-06-17 | Traditional Chinese medicine preparation for treating polymyalgia rheumatica and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610473113.2A CN106038843A (en) | 2016-06-17 | 2016-06-17 | Traditional Chinese medicine preparation for treating polymyalgia rheumatica and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106038843A true CN106038843A (en) | 2016-10-26 |
Family
ID=57166603
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610473113.2A Pending CN106038843A (en) | 2016-06-17 | 2016-06-17 | Traditional Chinese medicine preparation for treating polymyalgia rheumatica and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106038843A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1376502A (en) * | 2002-04-02 | 2002-10-30 | 谢群卿 | Chinese medicine for treating rheumatism |
| CN104547589A (en) * | 2015-01-23 | 2015-04-29 | 崔合芳 | Traditional Chinese medicine for treating polymyalgia rheumatica and applications of traditional Chinese medicine |
-
2016
- 2016-06-17 CN CN201610473113.2A patent/CN106038843A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1376502A (en) * | 2002-04-02 | 2002-10-30 | 谢群卿 | Chinese medicine for treating rheumatism |
| CN104547589A (en) * | 2015-01-23 | 2015-04-29 | 崔合芳 | Traditional Chinese medicine for treating polymyalgia rheumatica and applications of traditional Chinese medicine |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104288228A (en) | Traditional Chinese medicine composite for treating pain in neck, shoulders, waist and legs | |
| CN102988639B (en) | Medicament for treating cervical spondylosis and preparation method of medicament | |
| CN104857210A (en) | Traditional Chinese medicine combination preparation for treating fatty liver and preparation method thereof | |
| CN103977164A (en) | Traditional Chinese medicinal preparation for treating angina and preparation method | |
| CN106511905A (en) | Traditional Chinese medicine preparation used for curing cervical spondylosis and preparation method thereof | |
| CN105853562A (en) | Pharmaceutical preparation for treating asthma and preparing method | |
| CN105106634A (en) | Traditional Chinese medicine preparation for treating acute appendicitis and application thereof | |
| CN101934016B (en) | External medicament for treating arthritis | |
| CN105250959A (en) | Traditional Chinese medicine preparation for repairing liver damage and preparation method | |
| CN104383200A (en) | Traditional Chinese medicine preparation for treating dysmenorrhea and preparation method of traditional Chinese medicine preparation | |
| CN104887966A (en) | Traditional Chinese medicine preparation for treating lumbar muscle strain and preparation method thereof | |
| CN104474428A (en) | Traditional Chinese medicine preparation for treating spinal cord injury and preparation method | |
| CN104147277A (en) | Traditional Chinese medicinal preparation for treating myasthenia gravis and preparation method | |
| CN103961555A (en) | Traditional Chinese medicine preparation for treating peripheral nerve injury and preparation method thereof | |
| CN103989854A (en) | Traditional Chinese medicine preparation for treating ankylosing spondylitis and preparation method thereof | |
| CN103816450B (en) | A kind of Chinese medicine for the treatment of rheumatoid arthritis | |
| CN106038843A (en) | Traditional Chinese medicine preparation for treating polymyalgia rheumatica and preparation method thereof | |
| CN102872293A (en) | Traditional Chinese medicinal powder for treating rheumatism and rheumatoid disease | |
| CN101129651A (en) | Traditional Chinese medicine formulated product for treating cervical vertebra disease | |
| CN105770760A (en) | Preparation for treating gastric ulcer and preparation method thereof | |
| CN105456617A (en) | Oral-administrated traditional Chinese medicine pills for treating symptom of pathogenic fire derived from stagnation of liver and preparation method thereof | |
| CN105125964A (en) | Traditional Chinese medicine preparation for treating pelvic peritonitis and preparation method thereof | |
| CN104922595A (en) | Traditional Chinese medicinal preparation for herpes zoster and preparation method thereof | |
| CN105412484A (en) | Medicine for treating arthralgia, and preparation method thereof | |
| CN104721630A (en) | Traditional Chinese drug preparation used for anesthesia awakening and preparation method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB03 | Change of inventor or designer information |
Inventor after: Wang Yanming Inventor after: Wang Yonghua Inventor after: Ren Ruilian Inventor after: Wang Xiuyan Inventor after: Ji Yang Inventor before: Wang Qinhua Inventor before: Wang Yanming Inventor before: Ren Ruilian Inventor before: Wang Xiuyan Inventor before: Ji Yang |
|
| CB03 | Change of inventor or designer information |