CN106036850A - Traditional Chinese medicine health product having chloasma removing effect and preparation method thereof - Google Patents
Traditional Chinese medicine health product having chloasma removing effect and preparation method thereof Download PDFInfo
- Publication number
- CN106036850A CN106036850A CN201610409382.2A CN201610409382A CN106036850A CN 106036850 A CN106036850 A CN 106036850A CN 201610409382 A CN201610409382 A CN 201610409382A CN 106036850 A CN106036850 A CN 106036850A
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- China
- Prior art keywords
- chinese medicine
- parts
- health product
- chloasma
- rhizoma polygonati
- Prior art date
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
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- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
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- A—HUMAN NECESSITIES
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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Abstract
The invention provides a traditional Chinese medicine health product having a chloasma removing effect. The health product is an internal use medicine taking Chinese herbal medicines as main raw materials, and thus the shortcomings that in the prior art, external use medicines or surgical methods in chloasma treatment are poor in therapeutic effects and have side effects and chloasma reoccurs easily are overcome. The traditional Chinese medicine health product has the advantages of being green, safe, good in treatment effect and free of side effects and the like. The invention further provides a method for preparing the traditional Chinese medicine health product. The method is simple and convenient to operate, effective components in traditional Chinese medicine raw materials are effectively extracted, and the health product has the advantages that the health product preparation yield is high and the medicine effect is good.
Description
Technical field
The present invention relates to field of health care products, in particular to a kind of Chinese medicine health care product with functions of removing chloasma effect and
Its preparation method.
Background technology
Chloasma is that one is apt to occur in young and middle-aged women face, and is difficult to the hyperpigmentation dermatoses cured, clinical table
Now for occurring that limitation is filbert or brown pigment deposition, skin lesion is yellowish-brown or dark brown patch, be often symmetrically distributed in cheekbone portion,
Buccal.Owing to most chloasma show as symmetry pigementation, and precipitation is in wing shape, so having another name called butterfly spot.Additionally, by
In the brown of the liver that is similar in color of chloasma, therefore, chloasma is also known as chloasma hepaticum.Meanwhile, women period of gestation, due to pregnant
Reaction of being pregnent also results in there is pigementation on health, also can make to produce on face the brown speckle of butterfly-shaped distribution, thus yellow
Brown patch is also known as cyasma.
It is generally believed that chloasma to betide endocrine regulation relevant, research proof show, estrogen can stimulate black
Element emiocytosis melanin granule, progestogen can promote the transhipment of melanosome and increase melanin amount, ultimately resulting in melanin
Calm.Meanwhile, the generation of chloasma also has certain associating with sun exposure, and after transition light irradiates, chloasma can increase the weight of,
Avoid Exposure to Sunlight so that chloasma alleviates.
Owing to chloasma sickness rate is higher, chloasma also can directly affect appearance and attractive in appearance simultaneously, therefore become current the most very
The difficult problem that many women face.But, existing chloasma Therapeutic Method, main still employing is with the biological antioxygen such as polyphenol, Saponin
Agent is the externally used coating medicine of main component, and its cure rate is low, relapse rate height and DeGrain.And strip off therapy and laser treatment
Method also has certain side effect, it is not only possible to infringement or skin ambustion, is also easy to occur repeatedly, it is impossible to effectively cure chloasma.
Chinese medicine is China's traditional medicine, and compared to Western medicine or surgical operation for, Chinese medicine often therapeutic effect
More preferably and safety is good, side effect is little.Therefore, develop a kind of Chinese medicine composition for treating chloasma, particularly can be square
Health food that is the most daily edible with Chinese medicine composition as raw material and that have eliminating chloasma effect, is the most meaningful
, also there is the biggest research and development value and market prospect simultaneously.
In view of this, the special proposition present invention.
Summary of the invention
The first object of the present invention is to provide a kind of Chinese medicine health care product with functions of removing chloasma effect, described health product
The innerlich anwenden with Chinese herbal medicine as primary raw material, thus avoid in prior art in chloasma treatment external used medicine used or
The therapeutic effect of surgical method shortcoming poor, the most also side effect, Chinese medicine health care product of the present invention has green
The advantages such as safety, therapeutic effect are good and have no side effect.
The second object of the present invention is to provide the preparation method of a kind of described Chinese medicine health care product, the method operation letter
Just, and can effectively be extracted by active ingredient in raw material of Chinese medicine, have health product to prepare productivity height, good drug efficacy etc. excellent simultaneously
Point.
In order to realize the above-mentioned purpose of the present invention, spy by the following technical solutions:
A kind of Chinese medicine health care product for treating chloasma, in parts by weight, described Chinese medicine health care product mainly by with
Lower component is made: Flos Chrysanthemi 20-60 part, Radix Paeoniae Alba 5-40 part, Rhizoma Polygonati 5-30 part, Radix Angelicae Dahuricae 3-50 part, Rhizoma Polygonati Odorati 5-30 part, Folium Perillae
5-60 part, Radix Angelicae Sinensis 10-50 part, Semen Ginkgo 10-30 part.
In the present invention, described Flos Chrysanthemi has liver heat removing and eyesight improving, effect of heat-clearing and toxic substances removing；The described Radix Paeoniae Alba has regulating menstruation of fostering the spirit of nobility, flat
Subduing the hyperfunction of the liver sun, prevents the function of night sweat, dizziness etc., the most also has foster accurate adjustment blood, astringing YIN to stop sweating, effect of suppressing liver-YANG；Described
Rhizoma Polygonati has boosting qi and nourishing yin, spleen invigorating, lung moistening, promotes the production of body fluid, kidney benefiting functions；The described Radix Angelicae Dahuricae can detumescence and apocenosis, and leucorrhea abnormal is had
Improve effect；Described Rhizoma Polygonati Odorati has nourishing YIN to relieve dryness, effect of promoting the production of body fluid to quench thirst；Described Folium Perillae has relieving exterior syndrome and dispelling cold, the merit of relieving QI stagnancy in the stomach
Effect；Described Radix Angelicae Sinensis has tune blood and enriches blood, menstruction regulating and pain relieving, loosening bowel to relieve constipation, effect of promoting blood circulation to restore menstrual flow；Described Semen Ginkgo have leukorrhagia stopping turbid,
Dingchuan, effect of urine reducing, its rich in proteins, vitamin B2, carotene, calcium, phosphorus, the compound long-term taking such as ferrum can expand
Open blood capillary, blood circulation promoting, make people's skin ruddy, in high spirits.Further, in the present invention, by having above-mentioned
The herbal raw material of the effects such as sterilization, removing blood stasis to reduce swelling, boosting qi and nourishing yin with the use of so that health product of the present invention to have temperature logical
Blood vessels skin-active blood stasis dispelling, blood-nourishing and freckle-removing, effect of moist skin, and can effectively expand peripheral vessel, improve face microcirculation,
Horny layer softening, to pigmentation good inhibiting effect；Meanwhile, Chinese medicine composition of the present invention can also dispersing the stagnated live-QI to relieve the stagnation of QI, tune tonifying liver
Kidney, and can effective endocrine regulation, adjust the endocrine of the bodies of gland such as regulation hypophysis cerebri, adrenal gland, thyroid and ovary
Function, reduces melanic secretion, and further health product of the present invention can also expand blood vessel, promotes that microcirculation improves complexion,
And realize the effect such as effectively healing and whitening etc. of chloasma.Chinese medicine health care product of the present invention has that therapeutic effect is good, has no side effect
And the advantage such as not recurrence.
Optionally, in the present invention, in parts by weight, described Chinese medicine health care product is mainly made up of following components: Flos Chrysanthemi
30-50 part, Radix Paeoniae Alba 10-30 part, Rhizoma Polygonati 10-20 part, Radix Angelicae Dahuricae 5-40 part, Rhizoma Polygonati Odorati 10-20 part, Folium Perillae 10-50 part, Radix Angelicae Sinensis
20-40 part, Semen Ginkgo 15-25 part.
In the present invention, by adjusting further and optimizing each raw material components consumption, thus further increase this
The health-care effect of bright health product and the therapeutic effect to chloasma.
Optionally, in the present invention, the component of described Chinese medicine health care product still further comprises adjuvant and additive.
In the present invention, by adding adjuvant and additive further, so that health product of the present invention can be made further
Standby piece agent or potus, further facilitate and carry and take.
Meanwhile, present invention also offers the preparation method of described Chinese medicine health care product, concrete, described method includes walking as follows
Rapid: to soak after the Radix Paeoniae Alba, Radix Rehmanniae, Semen phaseoli radiati, Herba Menthae, Radix et Rhizoma Rhei (processed), Cortex Moutan, eight kinds of raw material of Chinese medicine mixing of Radix Glycyrrhizae, and decoct
Boil, obtain Aqueous extracts, precipitate with ethanol filtering after then Aqueous extracts being concentrated, then the ethanol evaporation in filtrate is removed, and will steam
Filtrate after Faing concentrates and receives cream, is dried to powder, and cream powder after being extracted is described health product.
In the present invention, Chinese medicine composition described in the application of the invention is raw material, and is prepared by steps such as decoction, precipitate with ethanol
Health product of the present invention such that it is able to the active ingredient in the present composition is effectively extracted, thus improve this further
The invention health product curative effect to chloasma.The inventive method has the advantages such as step is simple, health product productivity is high, effective.
Optionally, in the present invention, described method still further comprises cream powder after described extraction and adjuvant and additive
After mixing, prepare the step of health-care preparation.
In the present invention, by preparing health-care preparation after cream powder mixes with adjuvant, additive etc. after extraction further, from
And can further facilitate and carry and take.Meanwhile, can also improve in the present invention further by interpolation adjuvant and additive
The local flavor of medicine health product.
Optionally, in the present invention, described health-care preparation is tablet.Further, present invention additionally comprises cream after extraction
After powder mixes with adjuvant, additive, pulverize and sieve, pelletize, be dried, granulate, mixing, tabletting to be to prepare the step of troche of health products
Suddenly.
Optionally, in the present invention, described health-care preparation is potus.Further, present invention additionally comprises cream after extraction
After powder mixes with adjuvant, additive, adding water and heated and stirred, then canned after cooling, sterilizing is to prepare the step of potus.
Optionally, in the present invention, described adjuvant is one or both the mixture in calcium hydrogen phosphate, white sugar.
Optionally, in the present invention, described additive is plasticizer, stabilizer, emulsifying agent, sweeting agent, acidic flavoring agent, thickening
The mixture of one or more in agent, anticaking agents.Further, in the present invention, described additive is Macrogol 4000, gathers
Ethylene glycol 6000, microcrystalline Cellulose, hydroxypropyl methyl Starch Sodium, hydroxypropyl methyl cellulose, magnesium stearate, sucralose, two
The mixture of one or more in silicon oxide, citric acid, sodium citrate.
Optionally, in the present invention, after described extraction, the mass ratio of cream powder, adjuvant and additive is (4-8): (3-
8): (1-13).
In the present invention, by the further of cream powder, adjuvant and additive amount after extracting is adjusted and optimizes, thus can
To adjust and to optimize the local flavor of health product of the present invention further.
Optionally, in the present invention, described in soak during, the quality added water is described eight kinds of total matter of raw material of Chinese medicine
6-10 times of amount.
In the present invention, by decocting adjustment and the optimization of institute water consumption, so that the inventive method is effectively
Extract in herbal raw material while active ingredient, also will not waste and too much use water.
Optionally, in the present invention, the temperature of described decoction is 80-110 DEG C, and the time of decoction is 2-5h.
In the present invention, by decocting temperature and the adjustment of time and optimization, such that it is able to by the medicine in Chinese herbal medicine
While effect composition effectively extracts, additionally it is possible to improve the efficiency extracted further, thus improve the preparation of whole health product
Efficiency.
Optionally, in the present invention, the number of times of described decoction is 2-3 time.
In the present invention, by decocting the adjustment of number of times and optimization, such that it is able to by the active ingredient in raw material Chinese herbal medicine
While extracting, it is also possible to improve the preparation efficiency of health product of the present invention further.
Optionally, in the present invention, the concentration of ethanol used by described precipitate with ethanol is 65-85%.Further, described alcohol is dense
Degree is mass concentration.
In the present invention, by the adjustment of determining alcohol used by precipitate with ethanol and optimization, such that it is able to the impurity in extract is filled
Analyze precipitation, thus improve the purity of active ingredient in health product of the present invention, and then improve the chloasma of health product of the present invention
Therapeutic effect.
Optionally, in the present invention, the time of described precipitate with ethanol is 12-48h.
In the present invention, by the adjustment of precipitate with ethanol time and optimization, such that it is able to impurity in extract is effectively being removed
While, the overall preparation efficiency that also will not be caused due to precipitate with ethanol overlong time is too low.
Compared with prior art, the invention have the benefit that
(1), in the present invention, make by the herbal raw material with effects such as sterilization, removing blood stasis to reduce swelling, boosting qi and nourishing yins is coordinated
With, such that it is able to realize the regulation of human hormone, and then realize the effective treatment to chloasma.
(2), in the inventive method, Chinese medicine composition described in the application of the invention is raw material, and by decoction, precipitate with ethanol etc.
Step prepares health product of the present invention such that it is able to is effectively extracted by the active ingredient in the present composition, thus enters one
Step improves the health product of the present invention curative effect to chloasma.
(3) in the inventive method, by the adjustment of the step reaction conditions such as decoction, precipitate with ethanol and optimization, thus realizing
While in herbal raw material, active ingredient effectively extracts, additionally it is possible to improve overall preparation efficiency further.
(4), in the inventive method, by adding adjuvant and additive further, and its consumption is further adjusted
Whole and optimize, thus the tablet or potus conveniently taken can not only be prepared further, additionally it is possible to the wind to health product of the present invention
Taste further adjusts and optimizes.
Detailed description of the invention
Below in conjunction with embodiment, embodiment of the present invention are described in detail, but those skilled in the art will
Understanding, the following example is merely to illustrate the present invention, and is not construed as limiting the scope of the present invention.In embodiment unreceipted specifically
Condition person, the condition advised according to normal condition or manufacturer is carried out.Agents useful for same or instrument unreceipted production firm person, be
Can be by the commercially available conventional products bought and obtain.
Embodiment 1
According to parts by weight, weigh Flos Chrysanthemi 20 parts, the Radix Paeoniae Alba 5 parts, Rhizoma Polygonati 5 parts, the Radix Angelicae Dahuricae 3 parts, Rhizoma Polygonati Odorati 5 parts, Folium Perillae 5 respectively
Part, Radix Angelicae Sinensis 10 parts, Semen Ginkgo 10 parts；Then, put in extraction pot after eight kinds of raw material of Chinese medicine mixing as above, add 530
Part water soaking, and under the conditions of 80 DEG C, decoct 3h, and repeat to decoct 1 time, then obtain Aqueous extracts, then Aqueous extracts is concentrated
After, add the ethanol that mass concentration is 85% and sink 24h, then filter, and the ethanol evaporation in filtrate is removed, then will evaporation
After filtrate concentrate receive cream, be dried to powder, i.e. obtain cream powder after the extraction of embodiment 1, be the health product of embodiment 1.
Then, according to mass fraction, weigh respectively cream powder after the extraction of 20 parts of embodiments 1,25 parts of Macrogol 4000s, 30
Part calcium hydrogen phosphate, 10 parts of microcrystalline Cellulose and 5 parts of carboxylic hydroxypropyl methyl Starch Sodium, then sieve after each component mix homogeneously,
And add appropriate containing 1.5% hydroxypropyl methyl cellulose and the aqueous solution of 1.5% PVP K30, after sieving
Mixture carries out moistening bonding, then carries out pelletizing, being dried and arrange, is subsequently added into 1.5 parts of magnesium stearate, 1 part of silicon dioxide
And 2.5 parts of microcrystalline Cellulose, and tabletting after mix homogeneously, obtain the Chinese medicine health care product tablet of embodiment 1.
Embodiment 2
According to parts by weight, weigh Flos Chrysanthemi 60 parts, the Radix Paeoniae Alba 40 parts, Rhizoma Polygonati 30 parts, the Radix Angelicae Dahuricae 20 parts, Rhizoma Polygonati Odorati 30 parts, purple respectively
Revive 60 parts, Radix Angelicae Sinensis 50 parts, Semen Ginkgo 30 parts；Then, put in extraction pot after eight kinds of raw material of Chinese medicine mixing as above, add
2560 parts of water soakings, and under the conditions of 90 DEG C, decoct 5h, and repeat to decoct 2 times, then obtain Aqueous extracts, then that Aqueous extracts is dense
After contracting, add the ethanol that mass concentration is 85% and sink 36h, then filter, and the ethanol evaporation in filtrate is removed, then will steam
Filtrate after Faing concentrates and receives cream, is dried to powder, i.e. obtains cream powder after the extraction of embodiment 2, is the health product of embodiment 2.
Then, according to mass fraction, weigh respectively cream powder after the extraction of 35 parts of embodiments 2,30 parts of polyethylene glycol 6000s, 12
Part calcium hydrogen phosphate, 15 parts of microcrystalline Cellulose and 5 parts of carboxylic hydroxypropyl methyl Starch Sodium, and sieve, so after each component mix homogeneously
Rear addition contains 1.5% hydroxypropyl methyl cellulose and the aqueous solution of 1.5% PVP K30 in right amount, and will sieve
Rear mixture carries out moistening bonding, then carries out pelletizing, being dried and arrange, is subsequently added into 1.5 parts of magnesium stearate, 1 part of phosphoric acid hydrogen
Calcium and 5.5 parts of microcrystalline Cellulose, and tabletting after mix homogeneously, obtain the Chinese medicine health care product tablet of embodiment 2.
Embodiment 3
According to parts by weight, weigh Flos Chrysanthemi 30 parts, the Radix Paeoniae Alba 30 parts, Rhizoma Polygonati 10 parts, the Radix Angelicae Dahuricae 5 parts, Rhizoma Polygonati Odorati 20 parts, Folium Perillae respectively
10 parts, Radix Angelicae Sinensis 40 parts, Semen Ginkgo 15 parts；Then, put in extraction pot after eight kinds of raw material of Chinese medicine mixing as above, add
1600 parts of water soakings, and under the conditions of 95 DEG C, decoct 4h, and repeat to decoct 2 times, then obtain Aqueous extracts, then that Aqueous extracts is dense
After contracting, add the ethanol that mass concentration is 65% and sink 24h, then filter, and the ethanol evaporation in filtrate is removed and reclaims, so
After will evaporation after filtrate concentrate receive cream, be dried to powder, i.e. obtain cream powder after the extraction of embodiment 3, be the health care of embodiment 3
Product.
Then, according to mass fraction, weigh cream powder, 27 parts of white sugars, 1.5 parts of lemons after the extraction of 30 parts of embodiments 3 respectively
Lemon acid, 5 parts of sodium citrates, 0.08 part of sucralose, and sieve after each component mix homogeneously, then add water to 1000ml, and
It is heated to 90 DEG C of stirring 3h, then stops heating, and continue stirring at ambient temperature, when the temperature of mixed solution is down to 45 DEG C
Time, in mixed solution, add appropriate amount of essence and pigment, and canned, then wall-through sterilizing, i.e. obtain the health product of embodiment 3
Potus.
Embodiment 4
According to parts by weight, weigh Flos Chrysanthemi 50 parts, the Radix Paeoniae Alba 10 parts, Rhizoma Polygonati 20 parts, the Radix Angelicae Dahuricae 40 parts, Rhizoma Polygonati Odorati 10 parts, purple respectively
Revive 30 parts, Radix Angelicae Sinensis 20 parts, Semen Ginkgo 20 parts；Then, put in extraction pot after eight kinds of raw material of Chinese medicine mixing as above, add
1400 parts of water soakings, and under the conditions of 90 DEG C, decoct 4h, and repeat to decoct 2 times, then obtain Aqueous extracts, then that Aqueous extracts is dense
After contracting, add the ethanol that mass concentration is 75% and sink 40h, then filter, and the ethanol evaporation in filtrate is removed and reclaims, so
After will evaporation after filtrate concentrate receive cream, be dried to powder, i.e. obtain cream powder after the extraction of embodiment 4, be the health care of embodiment 4
Product.
Then, according to mass fraction, weigh cream powder, 25 parts of white sugars, 1.8 parts of lemons after the extraction of 40 parts of embodiments 4 respectively
Lemon acid, 5 parts of sodium citrates, 0.08 part of sucralose, and sieve after each component mix homogeneously, then add water to 1000ml, and
It is heated to 90 DEG C of stirring 3h, then stops heating, and continue stirring at ambient temperature, when the temperature of mixed solution is down to 45 DEG C
Time, in mixed solution, add appropriate amount of essence and pigment, and canned, then wall-through sterilizing, i.e. obtain the health product of embodiment 4
Potus.
Experimental example 1
It it is 30-45 year by 40 ages, hence it is evident that have the female volunteers of chloasma to be randomly divided into four groups, often organize 10 people.Often
Group takes the health product of embodiment 1-4 respectively, daily three times, each takes 50g, continuous 6 weeks.During testing, will
Hope person disables the medicine of the speckle dispelling of other oral and externals, but does not change the former dietary habit of volunteer.Then, the most right
Volunteer individually pays a return visit, and according to being wholly absent, substantially alleviate, slightly improve, unchanged and the Pyatyi such as increased
Standard, please volunteer evaluate and test and record the improvement chloasma effect of health product, and statistical result is as shown in the table:
After taking health product described in embodiment of the present invention 1-4 at continuous six weeks, please volunteer stop continuing to take the present invention
Health product, and under conditions of keeping original dietary habit, ask volunteer to disable other oral and external relevant skin cares and dispel
The medicine of chloasma, and after January, volunteer is paid a return visit, it was found that all volunteer's chloasma faciei situations are all protected
Hold or be slightly better than the state after cutting out health product of the present invention, chloasma corruptions does not occur, does not also find any pair
Effect.
Comparative example 1
According to parts by weight, weigh the Radix Paeoniae Alba 30 parts, Rhizoma Polygonati 10 parts, the Radix Angelicae Dahuricae 5 parts, Rhizoma Polygonati Odorati 20 parts, Folium Perillae 10 parts, Radix Angelicae Sinensis respectively
40 parts, Semen Ginkgo 15 parts.Then, put in extraction pot after eight kinds of raw material of Chinese medicine mixing as above, add 1600 parts of water loggings
Bubble, and the health product of comparative example 1 are prepared according to the step of embodiment 3.
Comparative example 2
According to parts by weight, weigh Flos Chrysanthemi 30 parts, Rhizoma Polygonati 10 parts, the Radix Angelicae Dahuricae 5 parts, Rhizoma Polygonati Odorati 20 parts, Folium Perillae 10 parts, Radix Angelicae Sinensis respectively
40 parts, Semen Ginkgo 15 parts.Then, put in extraction pot after eight kinds of raw material of Chinese medicine mixing as above, add 1600 parts of water loggings
Bubble, and the health product of comparative example 2 are prepared according to the step of embodiment 3.
Comparative example 3
According to parts by weight, weigh Flos Chrysanthemi 10 parts, the Radix Paeoniae Alba 30 parts, Rhizoma Polygonati 10 parts, the Radix Angelicae Dahuricae 5 parts, Rhizoma Polygonati Odorati 20 parts, Folium Perillae respectively
10 parts, Radix Angelicae Sinensis 40 parts, Semen Ginkgo 15 parts.Then, put in extraction pot after eight kinds of raw material of Chinese medicine mixing as above, add
1600 parts of water soakings, prepare the health product of comparative example 3 according to the step of embodiment 2.
Experimental example 2
It is 30-45 year by 30 ages, and has obvious chloasma female volunteers to be randomly divided into three groups, often organize 10 people.Often
Group takes the health product of comparative example 1-3 respectively, daily three times, each takes 50g, continuous 6 weeks.During testing, will
Hope person disables the medicine of the relevant skin care functions of removing chloasma of other oral and externals, but does not change the former dietary habit of volunteer.So
After, week about volunteer is individually paid a return visit, and according to being wholly absent, substantially alleviate, slightly improve, unchanged and have
Being increased etc. by five grade standards, volunteer please evaluate and test the improvement chloasma effect of health product record, statistical result is as follows
Shown in table:
In sum, health product of the present invention with Chinese herbal medicine as primary raw material, and can effective eliminating chloasma, take effect simultaneously
Hurry up, the most repeatedly, and without any side effects.
Although illustrate and describing the present invention with specific embodiment, but it will be appreciated that without departing substantially from the present invention's
May be made that in the case of spirit and scope many other change and amendment.It is, therefore, intended that in the following claims
Including all such changes and modifications belonged in the scope of the invention.
Claims (10)
1. one kind for having the Chinese medicine health care product of eliminating chloasma effect, it is characterised in that in parts by weight, described in
Medicine health product are mainly made up of following components: Flos Chrysanthemi 20-60 part, Radix Paeoniae Alba 5-40 part, Rhizoma Polygonati 5-30 part, Radix Angelicae Dahuricae 3-50 part,
Rhizoma Polygonati Odorati 5-30 part, Folium Perillae 5-60 part, Radix Angelicae Sinensis 10-50 part, Semen Ginkgo 10-30 part.
Health product the most according to claim 1, it is characterised in that in parts by weight, described Chinese medicine health care product is main
It is made up of following components: Flos Chrysanthemi 30-50 part, Radix Paeoniae Alba 10-30 part, Rhizoma Polygonati 10-20 part, Radix Angelicae Dahuricae 5-40 part, Rhizoma Polygonati Odorati 10-20
Part, Folium Perillae 10-50 part, Radix Angelicae Sinensis 20-40 part, Semen Ginkgo 15-25 part.
Chinese medicine health care product the most according to claim 1 and 2, it is characterised in that the component of described Chinese medicine health care product also enters one
Step includes adjuvant and additive.
The preparation method with the Chinese medicine health care product removing chloasma effect the most according to claim 1 and 2, its feature exists
In, described method comprises the steps:
By Flos Chrysanthemi, the Radix Paeoniae Alba, Rhizoma Polygonati, the Radix Angelicae Dahuricae, Rhizoma Polygonati Odorati, Folium Perillae, Radix Angelicae Sinensis, soak after eight kinds of raw material of Chinese medicine mixing of Semen Ginkgo, and decoct
Boil, obtain Aqueous extracts, precipitate with ethanol filtering after then Aqueous extracts being concentrated, then the ethanol evaporation in filtrate is removed, and will steam
Filtrate after Faing concentrates and receives cream, is dried to powder, and cream powder after being extracted is described health product.
Method the most according to claim 4, it is characterised in that described method still further comprises cream powder after described extraction
After mixing with adjuvant and additive, prepare the step of health-care preparation.
Method the most according to claim 5, it is characterised in that the quality of cream powder, adjuvant and additive after described extraction
Ratio is (4-8): (3-8): (1-13).
Method the most according to claim 4, it is characterised in that described in soak during, the quality added water is
8-10 times of described eight kinds of raw material of Chinese medicine gross masses.
Method the most according to claim 4, it is characterised in that the temperature of described decoction is 80-110 DEG C, the time of decoction
For 2-5h.
Method the most according to claim 4, it is characterised in that the number of times of described decoction is 2-3 time.
Method the most according to claim 4, it is characterised in that the concentration of ethanol used by described precipitate with ethanol is 65-85%.
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Inventor after: Cui Zhaochen Inventor before: Cui Zhaochen Inventor before: Wang Yu Inventor before: Liu Weiguo |
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Application publication date: 20161026 |