CN1060083C

CN1060083C - Traditional Chinese medicine bolus for treating pulmonary tuberculosis and method for preparing same

Info

Publication number: CN1060083C
Application number: CN97115216A
Authority: CN
Inventors: 高志海
Original assignee: Individual
Current assignee: Individual
Priority date: 1997-08-19
Filing date: 1997-08-19
Publication date: 2001-01-03
Anticipated expiration: 2017-08-19
Also published as: CN1208628A

Abstract

The present invention relates to a pill for treating phthisis and a preparation method thereof. The formula of the present invention comprises: 9 to 10 g of amomun fruit, 25 to 30 g of Chinese ephedra, 20 to 40 g of radix asteris, 10 to 15 g of licorice root, 15 to 20 g of Chinese angelica root, 20 g of astragalus root, 20 to 30 g of loquat leaf, 15 to 20 g of honeysuckle flower, 15 to 20 g of Jianqu, 18 to 20 g of haw, 10 g of Sichuan fritillary bulb, 15 to 20 g of bletilla tuber, 15 g of stemona root, 18 to 20 g of lilyturf root, 25 to 30 g of white mustard seed, 20g of schisandra fruit, rimifon, PS and/or 50 to 60 sheets of rifampin (0.5 g/ sheet). The raw materials are prepared into 120 pills, and each pill is about 9g. The clinical data indicates that the cure rate of the pill for treating phthisis is as high as 86.78%, and the total effective rate is 95.8%. The pill for treating phthisis has the advantages of no recurrence after cure, no toxic or side effect by taking the pill for a long term and no drug resistance. The pill for treating phthisis has curative effect on different types of patients and different types of phthises.

Description

Pulmonary tuberculosis pill and preparation method thereof

The present invention relates to a kind of phthisical Chinese herbal pill and preparation method thereof of specially controlling.

The western medicine pulmonary tuberculosis adopts isoniazid usually, to amido sodium salicylate and/or rifampicin, take the back toxic side effect for a long time, can develop immunity to drugs more easily recurrence of back.

The objective of the invention is to develop a kind of to the pulmonary tuberculosis cure rate is high, that do not recur after more, toxic and side effects is little and do not have Traditional Chinese medicine bolus for treating pulmonary tuberculosis of Drug resistance and preparation method thereof.

Traditional Chinese medicine bolus for treating pulmonary tuberculosis of the present invention is a kind of compositions, and material medicine is composed as follows:

Fructus Amomi 9-10 grams, Herba Ephedrae 25-30 grams, Radix Asteris 20-40 grams, Radix Glycyrrhizae 10-15 grams, Radix Angelicae Sinensis 15-20 grams, the Radix Astragali 20 grams, Folium Eriobotryae 20-30 grams, Flos Lonicerae 15-20 grams, Massa Medicata Fermentata 15-20 grams, Fructus Crataegi 18-20 grams, Bulbus Fritillariae Cirrhosae 10 grams, the Pseudobulbus Bletillae (Rhizoma Bletillae) 15-20 grams, the Radix Stemonae 15 grams, restrain Radix Ophiopogonis 18-20, Semen Sinapis Albae 25-30 grams, Fructus Schisandrae Chinensis 20 grams, isoniazid, to amido sodium salicylate and/or 50-60 of rifampicin (0.5 gram/sheet), make 120 balls altogether, every ball about 9 the gram.

Also can add following material medicine in the above-mentioned composition:

Radix Platycodonis 10-15 gram Radix Salviae Miltiorrhizaes 10-20 gram Cortex Lycii 10-15 grams

The preparation method of Traditional Chinese medicine bolus for treating pulmonary tuberculosis of the present invention is:

1. pick up the interior silt particle of clean medicine, foreign material etc., remove powder such as earth and foreign material with the scalping sieve;

2. by the coarse pulverization of said ratio elder generation, regrind into fine powder, stir;

3. use the ultraviolet radiation disinfection fine powder;

4. with the Mel heating and filtering, reuse copper pot decocts, and removes clean wax foam, endures to dropping liquid Cheng Zhu;

5. above-mentioned medicated powder and Mel are stirred, the garden of making about nine grams of every ball is spherical, after paper that the reuse disinfection by ultraviolet light is crossed and the wax shell packing, seals with wax.

Clinical data shows that Traditional Chinese medicine bolus for treating pulmonary tuberculosis is treated phthisical cure rate up to 86.78%, and total effective rate is 95.87%.Concrete condition is as follows:

Patient: male 1429 people, women 1406 people, totally 2835 people, age: 94 examples below 10 years old, 11-20 years old 235 example, 21-30 years old 1265 example, 31-40 years old 68 example, 41-50 years old 235 example, 51-60 years old 209 example, 116 examples more than 60 years old; The course of disease: 1699 examples of person below 6 months had 1775 examples in 6-12 months, 561 examples more than 12 months; Typing: primary pulmonary tuberculosis 680 examples, blood group are sent out type 420 examples, infiltrative type 1429 examples, chronic fiber air-conditioning-type 235 examples, tuberculous pleuritis 71 examples.

Instructions about how to take medicine: every day son, noon, the fourth of the twelve Earthly Branches, respectively obey 1 ball the 4 o'clock tenth of the twelve Earthly Branches, children's is cut down according to the circumstance.

The course of treatment: 4-6 months

The treatment standard:

1. cure: expectorant bacterium negative continuously (or cloudy continuously commentaries on classics), pathological changes absorb or do not have an activeness; The cavity

Closure all reaches above person half a year; If any the cavity, then need the cloudy continuously commentaries on classics of expectorant bacterium 1 year

Above person; General Symptoms disappears.

2. produce effects: General Symptoms obviously improves; The expectorant bacterium is cloudy continuously to be changeed, and pathological changes obviously absorbs or absorbs;

The cavity is closed or dwindle, and all reaches person more than three months.

3. effective: General Symptoms improves; Sputum conversion, pathological changes obviously absorb, absorb or do not have a change,

The cavity is closed, dwindles or does not have change, all reaches person more than month; The expectorant bacterium is continuous

Feminine gender, pathological changes absorbs, and the cavity dwindles, and all reaches person more than month.

4. invalid: General Symptoms, expectorant bacterium, X be red all not to have change.

Therapeutic outcome:

This is organized among the 2835 routine patients, and clinical cure 2461 examples account for 86.78%; Produce effects 209 examples account for 7.44%; Effective 48 examples account for 1.65%; Invalid 117 examples account for 4.13%, and total effective rate reaches 95.87%.2835 routine pulmonary tuberculosis case curative effect statistics

Cure	Produce effects	Effectively	Invalid	Add up to
Cure	Produce effects	Effectively	Invalid	Add up to	2461 86．78	209 7．44	48 1．65	117 4．13	2835 100％

Case one:

Open * *, man, 29 years old, the willow gulf miner people of Fenxi mineral bureau.Suffered from chronic fibro cavernous pulmonary tuberculosis 7 years, integrative therapy, the time heavy when light.When go to a doctor in October, 85, see that body is thin and weak, pale complexion, low grade fever, night sweat, tachypnea uncomfortable in chest, it is unable to cough, and abundant expectoration is rare clearly, sputum mixed with blood, spitting of blood is more than sometimes, indigestion and loss of appetite abdominal distention.Pale tongue, fat tender, there is indentation on the limit, and tongue is greasy in vain, deep,thready and forceless pulse.

Dialectical: deficiency of YIN leading to consumption of QI, the lung spleen causes impairment of purifying function of the lung with sick, and dysfunction of the spleen in transportation is the pathological changes in pulmonary tuberculosis later stage.Insufficiency of lung-QI, so cough is unable, shortness of breath and low voice; Failure of qi transforming fluid forms the expectorant disease, sees that then expectorant is clear rare and amount is many; The deficiency of vital energy can not Gu Wei, thus fever of the body, spontaneous perspiration.It is one QI failing to control blood then, the witness of the dysfunction of the spleen.

Diagnosis: pulmonary tuberculosis (deficiency of both QI and YIN)

Method of treatment: nourishing YIN and moistening the lung, replenishing QI to invigorate the spleen

Side's medicine: Traditional Chinese medicine bolus for treating pulmonary tuberculosis

Instructions about how to take medicine: every day son, noon, the fourth of the twelve Earthly Branches, respectively obey 1 ball the 4 o'clock tenth of the twelve Earthly Branches, eliminating cold for resuscitation water send down, period in a medicine is avoided clothes rareripe, living Bulbus Allii, tobacco and wine.

Nurse: note lying up, regulate nutrition.

Auxiliary examination: hemoglobin 8.5 grams, erythrocyte sedimentation rate 52mm/H, expectorant is coated with (+); X line film making is seen: the chronic fibro cavernous pulmonary tuberculosis progressive stage.

Therapeutic outcome: the back clothes Traditional Chinese medicine bolus for treating pulmonary tuberculosis of being admitted to hospital, instructions about how to take medicine are the same.Through treatment in two months, diet increased, and spirit takes a turn for the better, and spitting of blood stops, cough once in a while, and amount of expectoration reduces.X line perspective sees that focus absorbs to some extent.After four months, General Symptoms obviously improves, sputum conversion.Hospitalization is six months altogether, and General Symptoms disappears, and the cavity is closed, continuous four months cloudy commentaries on classics of expectorant bacterium.Recurrence is not followed up a case by regular visits in the coal mining of going into the well in May, 97 so far.

Case two:

The king * *, man, 33 years old, the cadre of Lingshi County county Party committee.Suffer from infiltrative pulmonary tuberculosis a year and a half, cough, hemoptysis, chest pain in the aggravation February of losing heart, is gone to a doctor in February, 82.Disease is seen emaciated physique, darkish complexion, and cough is violent, sputum mixed with blood, hoarseness, chest pain and shortness of breath, fever and sweating, poor appetite, purplish tongue, thready and hesitant pulse.

Dialectical: sick blood stasis for a long time, the respectful function of falling is lost in the lung pulse retardance, the sputum mixed with blood so cough is violent, congestion is not all right, and nutrient QI being deficient is defended heat, fever and sweating then, hypofunction of YANG QI in chest, chest pain and losing heart then, purplish tongue, thready and hesitant pulse is blood vessels levying of becoming silted up and hinder.

Diagnosis: pulmonary tuberculosis (QI and blood stasis type)

The rule of treatment: moistening the lung and resolving phlegm, the silt collateral dredging of dispelling.

Instructions about how to take medicine: from 6 o'clock mornings, every six hours clothes one balls, eliminating cold for resuscitation water sent down.Medication period is avoided clothes rareripe, living Bulbus Allii, the wine of banning on opium-smoking and the opium trade for a long time.

Nurse: have additional nutrients, lie up

Auxiliary examination: hemoglobin 8 gram %, erythrocyte sedimentation rate 48mm/H, light be coated with (+), X-ray film finding: right lung infiltrative pulmonary tuberculosis (progressive stage).

Therapeutic outcome: treated one month after annotating institute, the cough chest pain obviously alleviates, and expectorant is coated with cloudy the commentaries on classics, and all diseases disappear after March, and through laboratory examination, hemoglobin 13 restrains %, and erythrocyte sedimentation rate 2mm/H, expectorant are coated with continuous cloudy the commentaries on classics.The X sheet shows: right lung is dispersed in most point shape scleroma calcification shadows, and two lung marking are more coarse, follow up a case by regular visits to so far not recurrence in February, 92.

Clinical data shows that the effect of Traditional Chinese medicine bolus for treating pulmonary tuberculosis of the present invention is apparent and easy:

1. cure rate is up to 86.78%, total effective rate 95.87%.

2. follow up a case by regular visits to after more and show, do not recur after more.

3. the patient is followed up a case by regular visits to and show that Traditional Chinese medicine bolus for treating pulmonary tuberculosis has no side effect, no Drug resistance.

4. to the patient of all ages and classes, dissimilar pulmonary tuberculosis all has produce effects.

Claims

1. pulmonary tuberculosis pill, it is characterized in that material medicine is composed as follows: Fructus Amomi 9-10 grams, Herba Ephedrae 25-30 grams, Radix Asteris 20-40 grams, Radix Glycyrrhizae 10-15 grams, Radix Angelicae Sinensis 15-20 grams, the Radix Astragali 20 grams, Folium Eriobotryae 20-30 grams, Flos Lonicerae 15-20 grams, Massa Medicata Fermentata 15-20 grams, Fructus Crataegi 18-20 grams, Bulbus Fritillariae Cirrhosae 10 grams, the Pseudobulbus Bletillae (Rhizoma Bletillae) 15-20 grams, the Radix Stemonae 15 grams, restrain Radix Ophiopogonis 18-20, Semen Sinapis Albae 25-30 gram, Fructus Schisandrae Chinensis 20 grams, isoniazid, to 60-60 of the rifampicin of amido sodium salicylate and/or every 20.5 gram.

2. the method for making of Traditional Chinese medicine bolus for treating pulmonary tuberculosis as claimed in claim 1 is characterized in that:

(1) silt particle in the clean medicine of inspection, foreign material etc. remove powder such as earth and foreign material with the scalping sieve;

(2) by the coarse pulverization of said ratio elder generation, regrind into fine powder, stir;

(3) use the ultraviolet radiation disinfection fine powder;

(4) with the Mel heating and filtering, reuse copper pot decocts, and removes clean wax foam, endures to dropping liquid Cheng Zhu;

(5) above-mentioned medicated powder and Mel are stirred, the garden of making about nine grams of every ball is spherical, after paper that the reuse disinfection by ultraviolet light is crossed and the wax shell packing, seals with wax.