CN105998305A - Disinfection solution and preparation method and application thereof - Google Patents
Disinfection solution and preparation method and application thereof Download PDFInfo
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- CN105998305A CN105998305A CN201610531583.XA CN201610531583A CN105998305A CN 105998305 A CN105998305 A CN 105998305A CN 201610531583 A CN201610531583 A CN 201610531583A CN 105998305 A CN105998305 A CN 105998305A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/28—Mercury; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/65—Amphibians, e.g. toads, frogs, salamanders or newts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/234—Cnidium (snowparsley)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Abstract
The invention discloses a disinfection solution and a preparation method and application thereof. The disinfection solution is prepared from, by mass, 70-80 parts of ethanol medicine liquid, 8 parts of chloramphenicol and 12 parts of miconazole nitrate; the ethanol medicine liquid is prepared from, by mass, 35-45 parts of rhizoma coptidis, 25-35 parts of baical skullcap roots, 30-40 parts of Chinese corktree bark, 18-18.8 parts of cellulose and 800 parts of ethanol. The disinfection solution is convenient to use, and after sexual behaviors are conducted each time, the disinfection solution is directly sprayed on sexual organs and indirect sexual organs or skin; by means of a method of combining Chinese and western medicines, the disinfection solution has the advantages that disinfection is rapid, the disinfection effect is superstrong, and elimination is thorough.
Description
Technical field
The present invention relates to a kind of prevention and treatment of venereal diseases disinfection technology field, be specifically related to a kind of disinfectant solution and its preparation method and application.
Background technology
The infection of sexually transmitted disease (STD) is owing to unclean sexual behaviour produces, and the concrete route of infection are divided into again direct organ contagion
With non-substantivity organ contagion.Direct organ contagion refers to not use the protective measure substantivity organs such as condom
The infection that contact causes；Although non-substantivity organ contagion refers to take protective measure but by vaginal secretions and pubes
And the infection that skin causes.These route of infection are often misled by the publicity of mistake, think and have carried the condom will ' safety '！
This is also that the most online a lot of people asks: why he also can obtain the reason place of sexually transmitted disease (STD) and acquired immune deficiency syndrome (AIDS) with condom.Meanwhile,
Acquired immune deficiency syndrome (AIDS) is the pernicious infectious disease of the serious crisis human life that the most also cannot cure！And the main route of infection are to pass through
Spread through sex intercourse！How barrier propagates these route of infection and the propagation prevented AIDS, and needs exploitation in addition to condom
Disinfectant solution, as duplicate protection, is greatly lowered the probability of infection.
Summary of the invention
The deficiency existed for prior art, the present invention provides one can prevent and kill multiple sex desease virus, and as cutting
Disconnected spread of sexually transmitted diseases the disinfectant solution and preparation method thereof as sti prevention.
An object of the present disclosure is to provide a kind of disinfectant solution, and above-mentioned disinfectant solution is included the following: by mass parts
Ethanol medicinal liquid 70-80 part, 8 parts of chloromycetin, miconazole nitrate 12 parts；
Above-mentioned ethanol medicinal liquid extracts from the compositions of following mass parts:
Rhizoma Coptidis, 35-45 part, Radix Scutellariae, 25-35 part, Cortex Phellodendri, 30-40 part, cellulase, 18-18.8 part, ethanol, 800 parts.
Further, containing Flavonoids and the phenethanol glucosides class that mass fraction is 10-13% in above-mentioned ethanol medicinal liquid
The mixture of compound.
Further, above-mentioned composition also includes the dry rhizome that mass parts is 5-35 part Rhizoma Paridis.Water content is
Further, above-mentioned composition also includes the Mercury subsalicylate. that mass parts is 0.2-1 part.
Further, above-mentioned composition also includes the Venenum Bufonis that mass parts is 1 gram.
Further, above-mentioned composition also includes the Fructus Cnidii that mass parts is 2 grams.
Further, above-mentioned composition also includes the Radix Sophorae Flavescentis that mass parts is 10 grams.
Present invention also offers the preparation method of a kind of disinfectant solution, it is characterised in that: said method step is as follows:
The first step, divides preparation material by quality: Rhizoma Coptidis 35-45 part, Radix Scutellariae 25-35 part, Cortex Phellodendri 30-40 part, ethanol 1000ml or
800 parts；
Second step, is immersed in above-mentioned material in above-mentioned ethanol 24 hours, is subsequently adding catalyst fiber element enzyme, the addition of catalyst
It it is 18-18.8 part；
3rd step, then pulverizes 30 minutes with the ultrasonic echography of 25KHz frequency, and quickly fluid temperature is reduced to 20～25 degree；
4th step, it is that 20～25 degree of backflows propose device extraction 3 times and completed to extract in 2 hours, constant pressure that medicinal liquid adds temperature
Power is 2 atmospheric pressure；
5th step, the filter sizes of employing is that 100 mesh carry out ultrafiltration, obtains above-mentioned ethanol medicinal liquid, and above-mentioned ethanol medicinal liquid is homogeneous
Mutually or have trace drug precipitate, and containing mass fraction after concentrating is 10～13% Flavonoids and phenethanol glucosides class chemical combination
Thing；
6th step, by ethanol medicine liquid heating to 30 degree, according to mass parts ethanol medicinal liquid 70-80 part, 8 parts of chloromycetin, miconazole nitrate
12 parts, after mixing, it is sufficiently stirred for 30 minutes；
7th step, after question response temperature is down to room temperature, aseptic subpackaged after again filtering with 100 mesh.
Further, the temperature 36 of the catalytic reaction of above-mentioned catalyst～38 degree, the time of reaction is 2 hours.
Present invention also offers the application of above-mentioned disinfectant solution, above-mentioned disinfectant solution is applied to sti prevention, healthy reproduction cleaning-sterilizing,
Antiepidemic sterilizing field, and it is sprayed at genitals or skin or hair surface, above-mentioned sexually transmitted disease (STD) is common venereal diseases and HIV (human immunodeficiency virus).
The present invention has an advantage that
1. sterilization is quickly.Disinfectant solution described by this patent has superpower sterilizing function, can destroy antibacterial and disease within the extremely short time
Poison protein structure thus reach the purpose killed.
The most easy to use.As long as whether direct organ contact contacts after each sexual behaviour immediately with non-substantivity organ
Spray with this disinfectant solution and can kill the various sex desease virus on sexual organ and pubes and skin at once.
3. Integrated TCM, kills the most thoroughly.The present invention is a kind of to use Integrated TCM to make full use of Western medicine preparation
The principle of accuracy and the sterilization of Chinese medicine and removing toxic substances has the extract of superpower sterilizing function, and it directly acts on antibacterial and virus
Protein is allowed to recurring structure degeneration, dehydration, solidification, and removing toxic substances thoroughly destroys antibacterial and the protein structure of virus thus kills on earth
Go out antibacterial and virus purpose.
Detailed description of the invention
The present invention is the former of a kind of accuracy using Integrated TCM to make full use of Western medicine preparation and the sterilization of Chinese medicine and removing toxic substances
Reason has the extract of superpower sterilizing function, and it directly acts on the protein of antibacterial and virus and is allowed to recurring structure degeneration, dehydration,
Solidification, removing toxic substances thoroughly destroys antibacterial and the protein structure of virus thus kills antibacterial and the purpose of virus on earth.Because whether
The gonococcus of gonorrhea, the treponema pallidum of syphilis, the human papillomavirus of condyloma acuminatum, the herpes simplex virus of genital herpes,
Chancroid haemophilus ducreyi, nongonococcal urethritis chlamydia trachomatis Ureaplasma urealyticum, the most common fungus and mycete are drawn
The various genital diseases risen and their core of inhibition of HIV of acquired immune deficiency syndrome (AIDS) are all protein, and therefore this disinfectant solution is not only to respectively
Plant sex desease virus killing action and also HIV (human immunodeficiency virus) is had killing action simultaneously！
Embodiment 1
1.1 1 kinds of disinfectant solution.
Disinfectant solution is included the following: by mass parts
Ethanol medicinal liquid 70-80 part；8 parts of chloromycetin；Miconazole nitrate 12 parts；
Ethanol medicinal liquid extracts from the compositions of following mass parts: Rhizoma Coptidis, 35-45 part, Radix Scutellariae, 25-35 part, Cortex Phellodendri, 30-40 part,
Cellulase, 18-18.8 part, ethanol, 800 parts；
Compositions also includes the dry rhizome that mass parts is 5-35 part Rhizoma Paridis.
Ground compositions also includes the Mercury subsalicylate. that mass parts is 0.2-1 part.
Compositions also includes the Venenum Bufonis that mass parts is 1 gram.
Compositions also includes the Fructus Cnidii that mass parts is 2 grams.
Compositions also includes the Radix Sophorae Flavescentis that mass parts is 10 grams.
Containing Flavonoids and the mixing of phenethanol glucoside compound that mass fraction is 10-13% in ethanol medicinal liquid
Thing.
The using method of this disinfectant solution is very simple, after sexual behaviour terminates, be directly sprayed onto genitals with at the pubes contacted and skin
?.
1.2 bacteriostatic test.
Equipment: spectrophotometer；Pipettor；Automatic high pressure steam sterilization pan；Superclean bench；Constant incubator；Orifice plate,
Inoculating loop, toothpick, alcohol burner etc..
1.2.1 experiment material prepares
S1. band HIV (human immunodeficiency virus) blood, 1ML；
S2. gonococcus and culture fluid, 1ML；
S3. treponema pallidum and culture fluid, 1ML；
S4. the human papillomavirus of condyloma acuminatum and culture fluid, 1ML；
S5. chancroid haemophilus ducreyi and culture fluid thereof, 1ML；
S6. nongonococcal urethritis chlamydia trachomatis Ureaplasma urealyticum and culture fluid thereof, 1ML；
S7. fungus and culture fluid thereof, 1ML；
S8. mycete and culture fluid thereof, 1ML；
1.2.2 experimental procedure
The first step, the concentration of the disinfectant solution that method in embodiment 2 is made as benchmark concentration, dilute becomes 0.1,0.2,
0.3, the sample 1-sample 5 to be tested of 0.5,0.8,1.0 5 Concentraton gradient, component 5ML, once general used according to spraying
Disinfectant solution component is the minimum amount of 5 milliliters.
Pathogen culture liquid various in S1-S8 are joined in disinfectant solution gradient sample by second step；
3rd step, by sample 1 and the comparative sample of sample 5, observes fungistatic effect.
According to experimental result, 4th step, determines that Mlc is interval.
1.3 bacteriostatic test results
Shown in the following antibacterial gradient table 1 of experimental result:
Table 1: antibacterial gradient table
| Sample 1 | Sample 2 | Sample 3 | Sample 4 | Sample 4 | Sample 5 | |
| S1 | NG | NG | NG | |||
| S2 | NG | |||||
| S3 | NG | NG | ||||
| S4 | ||||||
| S5 | NG | |||||
| S6 | ||||||
| S7 | NG | NG | NG | NG | ||
| S8 | NG | NG | NG | NG |
Wherein: NG represents does not has bacteriostasis, blank to refer to compared with comparative sample, it is not changed in or to breed growing way more preferable.
Result: this disinfectant solution dilution one times is also had well sterilization and insect killing effect.
1.4 clinical trials:
Picking 100 volunteers's (from sex worker), provide free disinfectant solution, continuous observation 3 years, actual test is not the most sent out
Now infect any sexually transmitted disease (STD).
Embodiment 2
Present invention also offers the preparation method of a kind of disinfectant solution, it is characterised in that: method step is as follows:
The first step, divides preparation material by quality: Rhizoma Coptidis 35-45 part, Radix Scutellariae 25-35 part, Cortex Phellodendri 30-40 part, ethanol 1000ml or
800 parts；
Second step, soaks material 24 hours in ethanol, is subsequently adding catalyst fiber element enzyme, and the addition of catalyst is 18-18.8
Part；
3rd step, then pulverizes 30 minutes with the ultrasonic echography of 25KHz frequency, and quickly fluid temperature is reduced to 20～25 degree；
4th step, it is that 20～25 degree of backflows propose device extraction 3 times and completed to extract in 2 hours, constant pressure that medicinal liquid adds temperature
Power is 2 atmospheric pressure；
5th step, the filter sizes of employing is that 100 mesh carry out ultrafiltration, obtains ethanol medicinal liquid, and ethanol medicinal liquid is homogeneous phase or has micro-
Amount drug precipitation, and be 10～13% Flavonoids and phenethanol glucoside compound containing mass fraction after concentrating；
6th step, by ethanol medicine liquid heating to 30 degree, according to mass parts ethanol medicinal liquid 70-80 part, 8 parts of chloromycetin, miconazole nitrate
12 parts, after mixing, it is sufficiently stirred for 30 minutes；It addition, add the Camellia oil dregs of fat (tea seed cake or tea bran) leachate or extracting solution
10 parts, the leachate of employing, by 500 parts of Camellia oil dregs of fat micropowders, joins 3000 parts of 100 degree of hot water, supersonic oscillations 3
Hour, more isolated supernatant, it is leachate or extracting solution, is additionally added the mercury compound of 3 parts, 1 part of snake venom or snake venom
Extract, is stirred for 1 hour.
7th step, after question response temperature is down to room temperature, aseptic subpackaged after again filtering with 100 mesh.
Further, the temperature 36 of the catalytic reaction of catalyst～38 degree, the time of reaction is 2 hours.
Embodiment 3
Present invention also offers the application of above-mentioned disinfectant solution, disinfectant solution is applied to sti prevention, healthy reproduction cleaning-sterilizing, Antiepidemic sterilizing
Field, and it is sprayed at genitals or skin or hair surface, sexually transmitted disease (STD) is common venereal diseases and HIV (human immunodeficiency virus).
Below being only the preferred embodiment of the present invention, protection scope of the present invention is not limited merely to above-described embodiment, all genus
Technical scheme under thinking of the present invention belongs to protection scope of the present invention.It should be pointed out that, the common skill for the art
For art personnel, some improvements and modifications without departing from the principles of the present invention, these improvements and modifications also should be regarded as this
Bright protection domain.
Claims (10)
1. a disinfectant solution, it is characterised in that: described disinfectant solution is included the following: by mass parts
Ethanol medicinal liquid 70-80 part, 8 parts of chloromycetin, miconazole nitrate 12 parts；
Described ethanol medicinal liquid extracts from the compositions of following mass parts:
Rhizoma Coptidis, 35-45 part, Radix Scutellariae, 25-35 part, Cortex Phellodendri, 30-40 part, cellulase, 18-18.8 part, ethanol, 800 parts.
A kind of disinfectant solution the most according to claim 1, it is characterised in that: containing mass fraction in described ethanol medicinal liquid is 10-13%
Flavonoids and the mixture of phenethanol glucoside compound.
A kind of disinfectant solution the most according to claim 1, it is characterised in that: described compositions also including, mass parts is 5-35 part seven
The dry rhizome of leaf YIZHIHUA.
A kind of disinfectant solution the most according to claim 1, it is characterised in that: described compositions also including, mass parts is 0.2-1 part
Mercury subsalicylate..
A kind of disinfectant solution the most according to claim 1, it is characterised in that: described compositions also includes the toad that mass parts is 1 gram
Crisp.
A kind of disinfectant solution the most according to claim 1, it is characterised in that: described compositions also includes the Serpentis that mass parts is 2 grams
Machine tool.
A kind of disinfectant solution the most according to claim 1, it is characterised in that: described compositions also including, mass parts is 10 grams
Radix Sophorae Flavescentis.
8. the preparation method of disinfectant solution as described in any one of claim 1-7, it is characterised in that: described method step is as follows:
The first step, divides preparation material by quality: Rhizoma Coptidis 35-45 part, Radix Scutellariae 25-35 part, Cortex Phellodendri 30-40 part, ethanol 1000ml or
800 parts；
Second step, is immersed in described material in described ethanol 24 hours, is subsequently adding catalyst fiber element enzyme, the addition of catalyst
It it is 18-18.8 part；
3rd step, then pulverizes 30 minutes with the ultrasonic echography of 25KHz frequency, and quickly fluid temperature is reduced to 20～25 degree；
4th step, it is that 20～25 degree of backflows propose device extraction 3 times and completed to extract in 2 hours, constant pressure that medicinal liquid adds temperature
Power is 2 atmospheric pressure；
5th step, the filter sizes of employing is that 100 mesh carry out ultrafiltration, obtains described ethanol medicinal liquid, and described ethanol medicinal liquid is homogeneous
Mutually or have trace drug precipitate, and containing mass fraction after concentrating is 10～13% Flavonoids and phenethanol glucosides class chemical combination
Thing；
6th step, by ethanol medicine liquid heating to 30 degree, according to mass parts ethanol medicinal liquid 70-80 part, 8 parts of chloromycetin, miconazole nitrate
12 parts, after mixing, it is sufficiently stirred for 30 minutes；
7th step, after question response temperature is down to room temperature, aseptic subpackaged after again filtering with 100 mesh.
9. a disinfectant solution preparation method as claimed in claim 8, it is characterised in that: the temperature 36～38 of the catalytic reaction of described catalyst
Degree, the time of reaction is 2 hours.
10. the application of disinfectant solution as described in any one of claim 1-7, it is characterised in that: described disinfectant solution is applied to sti prevention,
Healthy reproduction cleaning-sterilizing, Antiepidemic sterilizing field, and it is sprayed at genitals or skin or hair surface, described sexually transmitted disease (STD) is common property
Disease and HIV (human immunodeficiency virus).
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| CN1367003A (en) * | 2002-01-28 | 2002-09-04 | 张在春 | Medicine for curing AIDS |
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