CN105998231A - External medicine for treating phlebitis and preparation method of external medicine - Google Patents

External medicine for treating phlebitis and preparation method of external medicine Download PDF

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Publication number
CN105998231A
CN105998231A CN201610602294.4A CN201610602294A CN105998231A CN 105998231 A CN105998231 A CN 105998231A CN 201610602294 A CN201610602294 A CN 201610602294A CN 105998231 A CN105998231 A CN 105998231A
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ethanol
days
external medicine
preparation
medicine
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肖琼芬
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/39Convolvulaceae (Morning-glory family), e.g. bindweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Insects & Arthropods (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention discloses an external medicine for treating phlebitis and a preparation method of the external medicine. The external medicine is prepared from the following raw materials by weight proportion: 50 to 100g of abutilon striatum, 25 to 100g of rhizoma coptidis, 25 to 100g of Chinese gall and 1000ml of ethanol. The preparation method comprises the following steps of mixing the abutilon striatum, the rhizoma coptidis and the Chinese gall according to proportions; then adding 50 to 95% ethanol, and placing into a sealed bottle; stirring for one time on first three days, and later stirring for one time every half month; soaking for 60 to 90 days, and taking filtrate, thus obtaining a finished product. The external medicine disclosed by the invention has the efficacies of subsiding swelling, detoxifying and healing sore, has a good curative effect for phlebitis at various stages and has no remarkable side effects.

Description

One treats phlebitic external used medicine and preparation method thereof
Technical field
The present invention relates to a kind of preparation method treating phlebitic external used medicine and this medicine.
Background technology
Theory of Chinese medical science is thought: phlebitis is that the many reasons such as repeated localised puncture and medicine irritation causes local venation hematogenous blockage, Blood stasis blocks, stagnation of QI and blood may bring about pain;Vim and vigour are smooth, and body fluid inputs swelling of being obstructed;Accumulate in blood stasis, accumulate long heat-transformation, then local pyrexia; Venation is damaged, and accumulates then local rubescent in blood oozing from the body openings or subcuta neous tissue skin or heat in blood.Traditional Chinese medicine therapy with heat clearing away, change congestion, eliminating stagnation, promote blood circulation It is main.
Current phlebitic treatment mainly uses following methods: partial closure, is coated with, hormone soak, ethanol or dense outside Chinese medicinal ointment Sodium chloride soak, local method is smashed local to pieces with Rhizoma Solani tuber osi or Radix et Caulis Opuntiae Dillenii and is applied, but therapeutic effect is inconspicuous, or recovers slower.
Summary of the invention
The technical problem to be solved is to provide one can effectively treat phlebitic external used medicine of each phase, and offer should The preparation method of medicine.
The present invention is with the following technical scheme above-mentioned technical problem of solution:
The present invention treats phlebitic external used medicine, is made up of the raw material mixing immersion of following weight proportion: Bell's 50-100 Gram, Rhizoma Coptidis 25-100 gram, Galla Chinensis 25-100 gram, ethanol 1000ml.
The present invention treats the preparation method of phlebitic external used medicine:
Add the ethanol that concentration is 50% 95% after Bell's, Rhizoma Coptidis and Galla Chinensis being mixed by proportioning, put into air-tight bottle, 3 Stirring it every day 1 time, the most every first quarter moon stirs 1 time, soaks 60 90 days, takes filtrate and i.e. obtain finished product.
The external used medicine of the present invention has effect of detumescence, removing toxic substances, sore, medicine of the present invention through the clinical practice more than 6 years, There is short treating period, each phase phlebitis is all had significant curative effect, herpes zoster is also had significant adjuvant treatment effect simultaneously, right Skin scald (without skin injury) also has significant curative effect.
The inventor of medicine of the present invention from 2009 so far, through the clinical practice of 6 years, Nanning first people Hospital application Herbal medicines for external use of the present invention treats 1000 many cases phlebitis, and effective percentage reaches 100%, and without obvious toxic and side effects.
Detailed description of the invention
Raw material used in inventive formulation, all uses common Chinese herbal medicine, medicine source to enrich, is prone to obtain.Each taste in formula Attribute and effect of herbal raw material are as follows:
1. Bell's: for the seed of convolvulaceous plant morning glory.Classification system: Pharbitis nil (Linn.) Choisy; Nature and flavor: cold in nature, bitter in the mouth;Poisonous;Gui Jing: return lung meridian, kidney channel, large intestine channel.Function cures mainly: removing water retention by purgation relieving constipation, and expectorant is washed Drink, parasite killing is attacked long-pending.For edema distension, constipation and anuresis, phlegm retention gathers, and QI rising in reverse order is breathed with cough, abdominal pain due to worm stagnation, ascarid, cestode Sick.
2. Rhizoma Coptidis: Coptis herbaceos perennial, takes rhizome and is used as medicine, containing multiple alkaloid.Classification system: Coptis chinensis Franch;Nature and flavor: cold in nature, bitter in the mouth;Gui Jing: GUIXIN, liver, stomach, large intestine channel;Function cures mainly: heat clearing away Pathogenic fire purging, dampness, removing toxic substances.For calentura, high heat is irritated, unconsciousness and delirium;Hyperactivity of heart-fire, chest and diaphragm heat is vexed, vexed insomnia, Aphtha of the mouth and tongue;Bleeding due to blood-heat, spits blood;Liver-fire conjunctival congestion and swelling pain;Gastropyretic vomiting, quenches one's thirst, gingival swelling and pain;The intestines and stomach is damp and hot, gastral cavity Abdomen feeling of fullness, has loose bowels, dysentery;Pathopyretic ulcer, eczema, scald.
3. Galla Chinensis: for the dry insect gall on Anacardiaceae plant Fructus rhois chinensis, potanin sumac or Radix Rhois Sinicae leaf, mainly by melaphis chinensis Baker Parasitic and formed;Classification system: Rhus chinensis Mill;Nature and flavor: it is cold in nature are sour in the mouth, puckery;Gui Jing: return lung, Large intestine, kidney channel;Function cures mainly: the hemostasis of pathogenic fire reducing of astringing the lung, relieving diarrhea with astringents, arresting sweating, removing dampness sore etc..For chronic cough of deficiency lung, The diseases such as chronic diarrhea chronic dysentery, hemorrhoidal bleeding of having blood in stool, carbuncle sore tumefacting virus, Skin wet and rotten.
The using method of medicine of the present invention: outer be coated with or soak, three times on the one, slight phlebitis (one, second phase) took effect the same day, Within 1~3 day, cure;Severe phlebitis (three, the fourth phase) takes effect for 1 day, within 5~7 days, cures.
Patient uses and is coated with or external application outside medicine of the present invention, and in a few hours, sensation phlebitis local is refrigerant, comfortable, and half a day feels pressure Alleviation of pain is light, causes phlebitis the most effective in cure transfusion.
The following is the specific embodiment of medicine of the present invention:
Embodiment 1:
Composition of raw materials: Jin Ling 100 grams, Rhizoma Coptidis 100 grams, Galla Chinensis 100 grams, ethanol 1000ml.
Its preparation method sequentially includes the following steps:
Adding the ethanol 1000ml that volumetric concentration is 75% after said herbal medicine being mixed, put into air-tight bottle, first three days stirs every day Mixing 1 time, the most every first quarter moon stirs 1 time, soaks 60 days, takes filtrate and i.e. obtain finished product.
Embodiment 2:
Composition of raw materials: Jin Ling 100 grams, Rhizoma Coptidis 70 grams, Galla Chinensis 70 grams, ethanol 1000ml.
Its preparation method sequentially includes the following steps:
Adding the ethanol 1000ml that volumetric concentration is 75% after said herbal medicine being mixed, put into air-tight bottle, first three days stirs every day Mixing 1 time, the most every first quarter moon stirs 1 time, soaks 70 days, takes filtrate and be finished product.
Embodiment 3:
Composition of raw materials: Jin Ling 75 grams, Rhizoma Coptidis 50 grams, Galla Chinensis 50 grams, ethanol 1000ml.
Its preparation method sequentially includes the following steps:
Adding the ethanol 1000ml that volumetric concentration is 75% after said herbal medicine being mixed, put into air-tight bottle, first three days stirs every day Mixing 1 time, the most every first quarter moon stirs 1 time, soaks 70 days, takes filtrate and be finished product.
Embodiment 4:
Composition of raw materials: Jin Ling 50 grams, Rhizoma Coptidis 50 grams, Galla Chinensis 50 grams, ethanol 1000ml.
Its preparation method sequentially includes the following steps:
Adding the ethanol 1000ml that volumetric concentration is 95% after said herbal medicine being mixed, put into air-tight bottle, first three days stirs every day Mixing 1 time, the most every first quarter moon stirs 1 time, soaks 60 days, takes filtrate and be finished product.
Embodiment 5:
Composition of raw materials: Jin Ling 50 grams, Rhizoma Coptidis 50 grams, Galla Chinensis 50 grams, ethanol 1000ml.
Its preparation method sequentially includes the following steps:
Adding the ethanol 1000ml that volumetric concentration is 50% after said herbal medicine being mixed, put into air-tight bottle, first three days stirs every day Mixing 1 time, the most every first quarter moon stirs 1 time, soaks 90 days, takes filtrate and be finished product.
Embodiment 6:
Composition of raw materials: Jin Ling 50 grams, Rhizoma Coptidis 50 grams, Galla Chinensis 25 grams, ethanol 1000ml.
Its preparation method sequentially includes the following steps:
Adding the ethanol 1000ml that volumetric concentration is 50% after said herbal medicine being mixed, put into air-tight bottle, first three days stirs every day Mixing 1 time, the most every first quarter moon stirs 1 time, soaks 90 days, takes filtrate and be finished product.
Embodiment 7:
Composition of raw materials: Jin Ling 50 grams, Rhizoma Coptidis 25 grams, Galla Chinensis 25 grams, ethanol 1000ml.
Its preparation method sequentially includes the following steps:
Adding the ethanol 1000ml that volumetric concentration is 50% after said herbal medicine being mixed, put into air-tight bottle, first three days stirs every day Mixing 1 time, the most every first quarter moon stirs 1 time, soaks 90 days, takes filtrate and be finished product.
The following is the checking example applying product of the present invention:
1, yellow XX, female, 35 years old, breast cancer postoperative chemotherapy, on May 09th, 2016, the right ancon PICC of row put pipe, put There is red and swollen heat pain in pipe initial stage local, and through changing dressings, process red and swollen heat pain is alleviated, but puts tube side elbow joint and can not stretch, right upper extremity In 140 degree of flexings, cephalic vein accessible longitudinally walking on elbow joint, long 5cm, the strip scleroma of wide 1cm, conscious There are sense of dragging and RIF feeling of numbness, asked nursing consultation May 24, be diagnosed as fourth phase phlebitis.Give local wet dressing Product of the present invention, using method: half range removes the transparent applicator of A/C, soak medicinal liquid with 4 layers of gauze and hold for 24 hours Continuous soak, finds after 1 day that bar rope thing reduces and shortens, the conscious right elbow joint of patient loosens, and sense of dragging alleviates, bar rope after 3 days Thing shortens to 1 × 0.5cm, and it is 180 degree that right elbow joint stretches, and changes into embrocating by product of the present invention after the 4th day, check in 7 days, The right elbow joint of patient can stretch, the most rotatable, and sense of dragging, forefinger numbness situation disappear.PICC conduit is retained Get off to continue chemotherapy to use.
2, XX slowly, man, 96 years old, it is diagnosed as pulmonary infection, is admitted to hospital on March 6th, 2016, right cervical region is inserted the most quiet Arteries and veins conduit, puts 10 days local of pipe and occurs red, swollen, hot, and harden 1 × 1cm, has purulent secretion, is defined as fourth phase vein Inflammation, locally gives the soak of this medicine, and red after 3 days, swollen, heat alleviates, and local desiccation is without secretions, and deliquescing of hardening, after 5 days Red, swollen, pyretolysis, scleroma is dissipated, is changed embrocating product of the present invention, transference cure after 7 days into.
3, yellow XX, man, 78 years old, be diagnosed as cerebral infarction sequela, be admitted to hospital on May 13rd, 2016, insert right stock quiet Arteries and veins conduit is used for infusion treatment, puts pipe and within 5 days, finds that local is red, swollen, hot, has purulent secretion, is defined as fourth phase phlebitis, Because patient's both limbs is paralysed, the pain sensation cannot judge.Giving product local wet dressing of the present invention, next day is red, swollen, heat alleviates, Secretions reduce, the 3rd day red, swollen, heat disappearance, local desiccation without secretions, the 5th day transference cure.
4, once XX, man, 84 years old, it is diagnosed as cancerometastasis before prostatitis, is admitted to hospital on February 14th, 2016, right forearm indwelling Pin infusion potassium chloride is red, swollen, hot to local, tenderness, and locally 2 × 2cm scleroma, is defined as three phase phlebitis, gives this Invention product local wet dressing, red after 1 day, swollen, hot, tenderness alleviates, and scleroma softens, and the 3rd day resolution of symptoms, scleroma disappears Dissipate, the 6th day transference cure.
5, old XX, man, 89 years old, it is diagnosed as pulmonary infection, is admitted to hospital on March 10th, 2016, remaining needle fat infusion Breast extravasation is the reddest, swollen, hot to local, tenderness, is defined as the second stage of phlebitis, gives product soak of the present invention, next day is red, swollen, Pyretolysis, the 4th day transference cure.
6, Lu XX, female, 80 years old, nephropathy diagnosis syndrome, it to be admitted to hospital on January 24th, 2016, retention needle infusion exosmoses To left forearm second phase phlebitis, there is red, swollen, hot, tenderness in local, gives product of the present invention and locally embrocates, next day symptom Alleviate, transference cure after 3 days.
7, permitted XX, female, 94 years old, be diagnosed as cerebral arteriosclerosis blood supply insufficiency, be admitted to hospital on May 8th, 2016, indwelling Pin transfusion extravasation, to left forearm second phase phlebitis, the reddest, swollen, hot, tenderness, is given to wipe outside product of the present invention local, 1 Red, swollen, pyretolysis after it, tenderness alleviates, and local can press, and continues coating pain disappearance after 3 days.
8, Lee XX, female, 24 years old, patient diagnosis was pulmonary infection, was admitted to hospital on January 8th, 2016, and transfusion extravasation is extremely The right hand back of the body is red, swollen, hot, tenderness, is defined as the second stage of phlebitis, gives product of the present invention and embrocate, and next day is red, swollen, heat disappears Losing, within second day, pain disappears.
9, Peng XX, man, 84 years old, it is diagnosed as cerebral arteriosclerosis blood supply insufficiency, is admitted to hospital on January 21st, 2016, stays Put that pin transfusion is red, swollen to left forearm, touch a tender spot, be defined as the second stage of phlebitis, give product of the present invention and embrocate, next day is red, swollen, Pyretolysis, the 3rd day transference cure.
Above phlebitis case, after product soak of the present invention or embrocating treatment, phlebitis all reaches to cure.Visible, this Bright product has detumescence, removing toxic substances, and effect of sore can solve skin soft tissue inflammatory injury, have excellent clinical effectiveness.

Claims (2)

1. treat phlebitic external used medicine for one kind, it is characterised in that this medicine is mixed leaching by the raw material of following weight proportion It is brewed to: Bell's 50-100 gram, Rhizoma Coptidis 25-100 gram, Galla Chinensis 25-100 gram, ethanol 1000ml.
2. the preparation method treating phlebitic external used medicine, it is characterised in that:
Proportioning raw materials is: Bell's 50-100 gram, Rhizoma Coptidis 25-100 gram, Galla Chinensis 25-100 gram, ethanol 1000ml;
Preparation technology is:
Add the ethanol that concentration is 50% 95% after Bell's, Rhizoma Coptidis and Galla Chinensis being mixed by proportioning, put into air-tight bottle, 3 Stirring it every day 1 time, the most every first quarter moon stirs 1 time, soaks 60 90 days, takes filtrate and i.e. obtain finished product.
CN201610602294.4A 2016-07-27 2016-07-27 External medicine for treating phlebitis and preparation method of external medicine Pending CN105998231A (en)

Priority Applications (1)

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Application Number Priority Date Filing Date Title
CN201610602294.4A CN105998231A (en) 2016-07-27 2016-07-27 External medicine for treating phlebitis and preparation method of external medicine

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101181559A (en) * 2007-11-22 2008-05-21 张树球 Chinese medicine preparation for curing fungi dermatosis and preparation method thereof
CN101596252A (en) * 2009-07-14 2009-12-09 王婷 A kind of composition and method of making the same for the treatment of herpes zoster
CN102847064A (en) * 2012-08-31 2013-01-02 苏捷 Chinese herbal medicine used for inhibition of malignant tumor metastasis
CN105194037A (en) * 2015-10-16 2015-12-30 黄金凤 Externally applied drug for treating phlebitis

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101181559A (en) * 2007-11-22 2008-05-21 张树球 Chinese medicine preparation for curing fungi dermatosis and preparation method thereof
CN101596252A (en) * 2009-07-14 2009-12-09 王婷 A kind of composition and method of making the same for the treatment of herpes zoster
CN102847064A (en) * 2012-08-31 2013-01-02 苏捷 Chinese herbal medicine used for inhibition of malignant tumor metastasis
CN105194037A (en) * 2015-10-16 2015-12-30 黄金凤 Externally applied drug for treating phlebitis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
沙莎: "中药外敷治疗化学性静脉炎的研究进展", 《中国中药杂志》 *

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