CN106138569A - A kind of Chinese medicine composition treating chronic wound and application thereof - Google Patents
A kind of Chinese medicine composition treating chronic wound and application thereof Download PDFInfo
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Abstract
The present invention relates to technical field of traditional Chinese medicine, be specifically related to a kind of Chinese medicine composition treating chronic wound and application thereof.The Chinese medicine composition of the treatment chronic wound of the present invention, in parts by weight, comprises following crude drug: Sanguis Draxonis 20 30 parts, 10 30 parts of Flos Carthami, Olibanum 5 10 parts, Myrrha 5 10 parts, 0.1 0.3 parts of Moschus, Borneolum Syntheticum 25 parts.The present invention is with Sanguis Draxonis as monarch drug, and Flos Carthami is ministerial drug, and Olibanum, Myrrha are adjuvant drug, and Moschus, Borneolum Syntheticum are for making medicine.The pathomechanism occur for chronic wound, be in progress, healed, uses Traditional Chinese medicine blood circulation promoting blood stasis dispelling, removing the necrotic tissue and promoting granulation, sore to combine.The theory of doctor trained in Western medicine moisture treatment, proves through clinical practice, treats all kinds of chronic wound.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine, be specifically related to a kind of Chinese medicine composition treating chronic wound and answer
With.
Background technology
Chronic wound is also referred to as skin ulcer, refractory wound surface, refers to that any failing has according to normal wound healing process
The wound healed within the scheduled time to sequence；The wound surface failing more than 3 months to heal can become chronic wound.
Chronic wound there may be the several years and do not heals even all the life, causes psychology and physical stress that patient is serious, and thus
Huge financial burden is brought to patient and whole health care system.
Along with aged tendency of population, body weight increases and increasing is secondary to the disease such as diabetes, impaired function of vein
Sick complication, chronic wound sufferer number significantly increases.According to statistics, the people of about 1% at it in life it may happen that leg
Ulcer., the most just there is the cost nearly 50-100 hundred million dollars of 300-600 ten thousand chronic wound these wound surface of patient treatment in the only U.S..
In China, according to epidemiological study result, in inpatients in surgical department, the ratio of chronic wound is about 1.5% to 20.3%.
In recent years, the patient of various chronic diseases increases year by year, causes associated pressure ulcer, diabetic foot, lower limb quiet
Also there is high incidence in the chronic wounds such as arteries and veins ulcer.As a example by diabetic foot, recent five years, world's onset diabetes rate is annual
With the surprising speed increment of 11%.The most existing suffer from diabetes close to 200,000,000 people, and it is the fifth-largest that the most therefore diabetes become the world
The cause of the death.By the estimation of IDF (IDF), current diabetes mellitus in China patient has reached fifty-five million people, annual new discovery sugar
Urine patient 120 people, and increase with the speed of people's every day at least 3000.In following 3 years to 5 years, these diabetes patients
Middle the patient having 15% can suffer from diabetic foot, serious will face amputation.
Additionally, along with the continuous aging of population, the sickness rate of venous leg ulcers and pressure ulcer rises constantly.
Although chronic wound will not life-threatening immediately, but because of up to even several years several months, the more than ten years are prolonged does not heals, seriously
Affect patient's protopathy rehabilitation and quality of life, also bring heavy nursing and financial burden to family.Minority can occur ulcer
Canceration.If occurring to infect diffusion, may result in the complication such as sepsis, not only increasing the weight of protopathy but also threat to life.
Chronic wound is different from general traumatic surface, and its traumatic condition is increasingly complex.No matter pathogenesis, site of pathological change or
The aspects such as antibacterial infection conditions, Pathologic changes, have different epidemiology and pathological characteristic, and wound repair method is the most not to the utmost
Identical.Its cause of disease many bad with traumatic infection, locally blood supply, diabetes, radioactivity are relevant.So fundamentally to cure or to control
System carries out Comprehensive Treatment within normal range.
The treatment of chronic wound relates to many such as the department of Chinese medicine, Dept. of Hyperbaric Oxygen, department of general surgery, orthopaedics, department of dermatologry, department of endocrinology
Section, the method for the treatment of divides No operation and operative treatment.Non-operative treatment includes: topical agent；Various dressing；Various naturopathy
Means (sound, light, heat, electricity etc.)；Vacuum suction；Guan Bi vacuum suction；Somatomedin；Also can be by hyperbaric oxygentherapy.Operation side
Method includes: debridement and suturing；Skin-grafting；Big foreign body skin covers；Various local or axial skin flap；Microsurgery tissue transplantation；Neural,
Blood vessel, the micro suture of tendon and transplanting etc..
Over the past thousands of years, the Chinese medicine external of motherland's medical science but has the curative effect of uniqueness to wound healing.External application Chinese medicine is promoted
The use mechanism of wound healing, the traditional Chinese medical science has saying of " removing the necrotic tissue and promoting granulation being snuggled up to pus and put on flesh ", and existing research shows, external application Chinese medicine can promote
Wound surface secretion a large amount of consistence things, i.e. " pus ".In wound healing mid-term, this " pus " liquid is the most, then wound healing is the fastest, this and doctor trained in Western medicine
In moisture treatment play the same tune on different musical instruments part.Thus, the active ingredient of application modern science and technology prize external Chinese medicament purifies, and
Figuration, in new pattern compress, plays a role jointly, promotes the healing of wound surface further.
Summary of the invention
It is an object of the invention to overcome the deficiencies in the prior art, it is provided that a kind of Chinese medicine composition treating chronic wound
And application.The present invention is with Sanguis Draxonis as monarch drug, and Flos Carthami is ministerial drug, and Olibanum, Myrrha are adjuvant drug, and Moschus, Borneolum Syntheticum are for making medicine.For slowly
Property the wound surface pathomechanism that occurs, be in progress, heal, use Traditional Chinese medicine blood circulation promoting blood stasis dispelling, removing the necrotic tissue and promoting granulation, sore to combine.The moist treatment of doctor trained in Western medicine
The theory of method, proves through clinical practice, treats all kinds of chronic wound.
The purpose of the present invention is achieved through the following technical solutions:
The first object of the present invention is to provide a kind of Chinese medicine composition treating chronic wound, in parts by weight, comprises
Following crude drug: Sanguis Draxonis 20-30 part, Flos Carthami 10-30 part, Olibanum 5-10 part, Myrrha 5-10 part, Moschus 0.1-0.3 part, Borneolum Syntheticum 2-
5 parts.
Further, described Chinese medicine composition, in parts by weight, comprise following crude drug: Sanguis Draxonis 30 parts, 20 parts of Flos Carthami,
Olibanum 10 parts, Myrrha 10 parts, 0.2 part of Moschus, Borneolum Syntheticum 2 parts.
Further, described Chinese medicine composition can be made into oil immersion liquid, hydrocolloid or contains drug solns.
Further, the preparation method of described oil immersion liquid is as follows: weighting raw materials, takes 1500ml olive oil and is heated to 120
DEG C-150 DEG C put into Flos Carthami, keep this temperature, treat that Flos Carthami is decocted to sallow, filter, retain filtrate；Insert Olibanum, Myrrha, stir cold
But to 50 DEG C-80 DEG C, insert Sanguis Draxonis, Moschus, Borneolum Syntheticum, stir natural cooling, place 24 hours and filter standby.
Further, the preparation method of described hydrocolloid is as follows: weighting raw materials, with liquid-solid extraction method from crude drug
Extract original liquid, using 60vol% ethanol as Extraction solvent, 1.5 hours extraction times, Extracting temperature 60 DEG C, solid-liquid ratio 1:30,
Extract to obtain original liquid, then original liquid is mixed by weight 30-45:100 with Carboxymethyl cellulose sodium, pectin or gelatin, system
Standby one-tenth water soluble hydrocolloids.
Further, the described preparation method containing drug solns is as follows: extract former medicine from crude drug with liquid-solid extraction method
Liquid, using ethanol as Extraction solvent, 1.5 hours extraction times, Extracting temperature 60 DEG C, volume fraction of ethanol 60%, crude drug with
Weight ratio 1:30 of ethanol, extracts to obtain original liquid, then is arranged to containing concentration be the pharmaceutical extraction of 30-45wt% with sterilized water
Thing solution.
The second object of the present invention is to provide above-mentioned Chinese medicine composition in preparation treatment treatment chronic wound medicine
Application.
Further, after described Chinese medicine composition being made oil immersion liquid, hydrocolloid or containing drug solns, infiltrate or be coated on algae
Hydrochlorate fabric, is prepared as pastille dressing.
Each crude drug Action Specification in Chinese medicine composition of the present invention is as follows:
Sanguis Draxonis: babassu, the resin in the brown fruit of kylin and rattan.Nature and flavor: sweet, salty, flat, GUIXIN, liver spleen channel.Merit
Effect: promoting blood circulation to remove blood stasis, analgesic therapy for oral administration, external hemostasia and promoting granulation, sore.Sanguis Draxonis water logging agent (1:2) is to trichophyton, the most blue achorion, Austria
Du big belly little spore tinea bacterium, rust little spore tinea bacterium, ulotrichy little spore tinea bacterium, epidermophyton inguinale, color bead-containing bacteria, star
Shape slave blocks the dermatophytess such as bacterium all inhibitory action in various degree.Also having report to point out, Sanguis Draxonis is to staphylococcus aureus, lemon
Lemon color staphylococcus, Nai Shi coccus, diphtheria corynebacterium and Bacillus typhi have the strongest bacteriostasis.To escherichia coli, bacillus pyocyaneus,
Shigella flexneris etc. have stronger bacteriostasis.Sanguis Draxonis also has antiinflammatory action, and suppression platelet aggregation accelerates platelet electricity
Swimming speed, still has significant anti thrombotic action.But clotting time, prothrombin time and blood viscosity are had no significant effect.Join not
Medicine, Olibanum, the power of its promoting blood circulation and breaking stagnation strengthens, blood activating and promoting tissue regeneration sore again, therefore can be used for malignant boil, carbuncle, do not close up for a long time, gold is created
Blood, wound such as do not conform at the disease.
Flos Carthami: Flos Carthami is Compositae platymiscium, has another name called Flos Carthami, red Cymbidium ensifolium (L.) Sw. etc., 1 year or biennial herb.Warm in nature, return
The heart, liver two, gas perfume (or spice) row dissipates, enters blood system.Have invigorate blood circulation, blood stasis dispelling, analgesic efficacy.
Olibanum: for olive subject plant.The oleo-gum-resin that the skin zones such as Boswellia carterii, Bao Da Boswellia carterii, wild Boswellia carterii ooze out, taste
Pungent, bitter, slightly warm in nature, GUIXIN, liver, spleen channel.Effect: blood-activating and qi-promoting, inducing menstruation to relieve menalgia, detumescence and promoting granulation, cures mainly traumatic injury stasis of blood pain, and carbuncle swells
Poison, the sore being festered and unhealed.
Myrrha: for olive subject plant.If the oleo-gum-resin that loblolly tree and congener trunk skin zone ooze out, bitter in the mouth, property are flat, return
Liver, spleen, the heart, kidney channel.Effect: promoting blood circulation and stopping pain, detumescence and promoting granulation, cures mainly carbuncle skin infection.
Moschus: for animal in deer family.Woods Moschus moschiferous, horse Moschus moschiferous or the dry secretions of former Moschus moschiferous maturation hero body adenocele.Acrid in the mouth, property
Temperature, GUIXIN, liver, spleen channel.Effect: refreshment of having one's ideas straightened out, promoting blood circulation to restore menstrual flow, removing obstruction for relieving pain, its pungent perfume (or spice) of property walks to alter, and outer and skin hair key is without institute
Do not reach.
Borneolum Syntheticum: for Dipterocarpaceae aiphyllium plant, the processed finished products of Borneolum Syntheticum resin or the trunk of Borneolum Syntheticum through distillation
Crystallize obtained by cooling, claim " borneol ".By the sublimate of Compositae perennial herb thing thing Herba Blumeae Balsamiferae (great Ai) processed split cut and
Become, claim " Blumeae preparatum Tabellae ".Existing multiplex Oleum Terebinthinae, Camphora etc., through being chemically synthesized, claim " BORNEOLUM SYNTHETICUM ".Acrid in the mouth is bitter, cool in nature, GUIXIN
Warp, Xin Xiang walks to alter, and pungent scattered bitter pond, is use with Moschus mutual reinforcement between, and the two one high one delays, reducing swelling and alleviating pain, and has the antipruritic effect of anticorrosion, clear
Thermal detoxification, erosion prevention and muscle growing.
The present invention is directed to generation and the healing mechanism of chronic wound, through clinical practice for many years, it is believed that chronic wound because of
Stagnation of QI-blood heresy poison enters flesh, blood circulation promoting and blood stasis dispelling in treatment, promoting tissue regeneration and ulcer healing after first removing the necrotic tissue.Select Chinese medicine for this present invention, extract through science
Take active ingredient and be prepared as hydrocolloid, replenisher, and figuration on alginate fabric, direct external application or fill wound surface, the most effectively
Rate reaches 86%, evident in efficacy.
Accompanying drawing explanation
Fig. 1 is the therapeutic process wound surface picture of case one；Wherein, before a is for treatment, after b is for treating February；
Fig. 2 is the therapeutic process wound surface picture of case two；Wherein, before a is for treatment, after b is for treating February；
Fig. 3 is the therapeutic process wound surface picture of case three；Wherein, a is that wound surface opens wide, and b is with containing the former medicine attached type of oil immersion liquid
Wound is filled in dressing；C is for add interruption vacuum suction continued treatment containing former medicine oil immersion liquid dressing.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is expanded on further.Should be understood that these embodiments are merely to illustrate the present invention
Rather than restriction the scope of the present invention.
Embodiment 1 treats Chinese medicine composition and the preparation thereof of chronic wound
A kind of Chinese medicine composition treating chronic wound, in parts by weight, comprises following crude drug: Sanguis Draxonis 30 parts, Flos Carthami
20 parts, Olibanum 10 parts, Myrrha 10 parts, 0.2 part of Moschus, Borneolum Syntheticum 2 parts.
Above-mentioned Chinese medicine composition is prepared as respectively oil immersion liquid, hydrocolloid or contains drug solns:
1, the preparation of oil immersion liquid: weighting raw materials, 1500ml olive oil is put and is heated to 120 DEG C-150 DEG C in copper pot and puts into red
Flower, keeps this temperature, treats that Flos Carthami is decocted to sallow, filters and inserts Olibanum, Myrrha, and stirring is cooled to 50 DEG C-80 DEG C, insert Sanguis Draxonis,
Moschus, Borneolum Syntheticum, stir natural cooling, places 24 hours and filters standby.
2, the preparation of hydrocolloid: weighting raw materials, extracts original liquid with liquid-solid extraction method from crude drug.Extract after deliberation
Take optimum condition: select ethanol as Extraction solvent, 1.5 hours extraction times, Extracting temperature 60 DEG C, volume fraction of ethanol
60%, solid-liquid ratio 1:30, extract to obtain original liquid, then by original liquid with Carboxymethyl cellulose sodium, pectin or gelatin by weight
30-45:100 mixes, and is prepared as water soluble hydrocolloids.
3, the preparation containing drug solns (replenisher) extracts original liquid with liquid-solid extraction method from crude drug.Extract after deliberation
Optimum condition: select ethanol as Extraction solvent, 1.5 hours extraction times, Extracting temperature 60 DEG C, volume fraction of ethanol 60%,
Solid-liquid ratio 1:30, extracts to obtain original liquid, and the pharmaceutical extraction thing being then arranged to containing concentration is 30-45wt% with sterilized water is molten
Liquid.
Embodiment 2 treats the clinical application effect evaluation of the Chinese medicine composition of chronic wound
The dressing using embodiment 1 preparation carries out clinical treatment, is described as follows:
1, case selection
All cases are selected from January, 2012 to my gate emergency treatment, inpatient, totally 100 example of in December, 2015, divide at random
Become treatment group and each 50 examples of matched group.Male 31 examples for the treatment of group, female 19 example, age 49-88 year, average 68.2 years old；Wherein, severe cranium
Brain injury 7 example, cerebral infarction 15 example, cerebral hemorrhage 8 example, respiratory failure 2 example, heart failure 3 example, high paraplegia 2 example, complication with diabetes
29 examples.Inclusion criteria: failed more than 3 months healing wound surface, wherein pressure ulcer 52 example (treatment group 28 example, matched group 24 example), under
Limb venous ulcer 11 example (treatment group 7 example, matched group 4 example).Diabetic ulcer 21 example (treatment group 9 example, matched group 12 example),
Reason the brightest wound surface 16 example (treatment group 6 example, matched group 10 example).Left card side inspection respectively in terms of age, sex, the state of an illness between two groups
Test, no significant difference (P 0.05), between two groups, there is comparability.
2. Therapeutic Method:
2.1 treatment groups: patient uses oil immersion liquid dressing, hydrocolloid prepared by embodiment 1 or composes containing drug solns (replenisher)
The alginate fabric dressing external application wound surface of shape, is spaced replacing in 1-2 days.
2.2 persistently close in negative pressure treatment at wound surface, with Chinese medicine composition extract solution (the i.e. pastille containing embodiment 1
Solution) retain every day and rinse secondary.
2.3 matched groups: clean after wound surface with 1:5000 furacilin solution, then with sterile vaseline gauze and other dressing
Wrapping, cleans and changes once, do efficacy evaluation after 8 weeks for 1-2 days.
3. curative effect determinate standard
The People's Republic of China's traditional Chinese medicine industry standard issued with reference to State Administration of Traditional Chinese Medicine " examine by surgery of Chinese medicine disease
Disconnected criterion of therapeutical effect ", Ministry of Public Health " new Chinese medicine clinical research guide " formulate curative effect grade scale.
Recovery from illness: wound surface heals completely, clinical symptom disappearance, follows up a case by regular visits to 2 months without recurrence.
Effective: wound surface area reduces and reaches more than 70%, and clinical symptoms disappears substantially.
Take a turn for the better: wound surface area reduces and reaches more than 30%, and clinical symptoms is improved.
Invalid: wound surface area reduces less than 30% or unchanged or expansion, and clinical symptoms is without improving.
4. therapeutic effect: two groups of patients after curative treatment compare and are shown in Table 1
Two groups of patients after curative treatment compare (table 1)
Note: P 0.05 compared with matched group
Two groups of comparitive study, treatment group cure rate, total effective rate are substantially better than matched group, have comparability, P 0.05.
In above-mentioned case, pick out 3 model cases and describe in detail
Case one: Lee XX, women, 78 years old.After cerebral hemorrhage, paralysis bed more than 2 years, the huge decubital ulcer of left side hip, go deep into bone
Bone face.Fig. 1 a is the wound surface before treatment, and Fig. 1 b is the wound surface after treating February, it will be seen from figure 1 that wound healing is effective.
Case two: XX male Cai, 72 years old, parkinson, lie in bed 3 years, left ischial tuberosity portion decubital ulcer more than a year, the VI phase.
Fig. 2 a is the wound surface before treatment, and Fig. 2 b is the wound surface after treating February, figure it is seen that through bimestrial treatment, wound surface
Fully recover, do not recur so far.
Case three: Shen XX, male, 64 years old, patient 2007.11.28 was because of " aching pain in waist and back companion's left lower extremity is numb " morbidity two weeks
Being admitted to hospital, MRI points out Spinal canal encroachment, and 2007.12.03 detects at general anesthesia descending T6-8 laminectomy for decompression, canalis spinalis, Intraspinal neoplasm
Enucleation.Postoperative there is incontinence of urination and defecation, and abdominal reflex exist, and right side stomach wall feels to drop to umbilical plane, under left side stomach wall sensation
Dropping to groin, anus has light contraction function.
Post operative diagnosis: 1, intramedullary spinal tumor is postoperative 2, below T6 paraplegia
2008.02.02 leaving hospital, 2008.02.18 is admitted to hospital again, finds " right leg outer side has size about 2*2cm pressure ulcer ".
Diameter 3cm decubital ulcer seen from hip on the right side of in the of 2009.12, wound surface is the most dry clean.
On the right side of in the of 2010.10, buttocks has diameter 6cm pressure ulcer, and wound surface oozes out on a small quantity, and granulation tissue is the freshest.
Having diameter 8cm pressure ulcer on the right side of in the of 2011.12 outside buttocks, wound surface oozes out on a small quantity, and granulation tissue owes fresh.
Being respectively arranged with diameter 9cm pressure ulcer on the right side of in the of 2013.01 outside buttocks, wound surface oozes out on a small quantity, and granulation tissue owes fresh.
2014.03.18 the descending right hip decubitus wound debridement of general anesthesia.
2014.03.25,39.5 DEG C of high heat occur, opens wide (such as Fig. 3 a) through wound surface, strengthen negative pressure drainage, hyperpyrexia.
2014.03.29 to fill wound (such as Fig. 3 b) containing the attached type dressing of former medicine oil immersion liquid, use and be interrupted punching containing drug solns
Wash, high febrile lysis.After with containing former medicine oil immersion liquid add interruption vacuum suction continued treatment (such as Fig. 3 c).
2015.06.18 patient leaves hospital automatically.While in hospital occurs without high heat again.
Below preferred embodiment to the invention is illustrated, but the invention is not limited to described
Embodiment, those of ordinary skill in the art also can make all equivalents on the premise of the invention spirit
Modification or replacement, modification or the replacement of these equivalents are all contained in the application claim limited range.
Claims (8)
1. treat a Chinese medicine composition for chronic wound, in parts by weight, comprise following crude drug: Sanguis Draxonis 20-30 part, Flos Carthami
10-30 part, Olibanum 5-10 part, Myrrha 5-10 part, Moschus 0.1-0.3 part, Borneolum Syntheticum 2-5 part.
A kind of Chinese medicine composition treating chronic wound the most according to claim 1, it is characterised in that: described Chinese medicine composition
Thing, in parts by weight, comprises following crude drug: Sanguis Draxonis 30 parts, 20 parts of Flos Carthami, Olibanum 10 parts, Myrrha 10 parts, 0.2 part of Moschus, ice
Sheet 2 parts.
A kind of Chinese medicine composition treating chronic wound the most according to claim 1, it is characterised in that: described Chinese medicine composition
Thing can be made into oil immersion liquid, hydrocolloid or contains drug solns.
A kind of Chinese medicine composition treating chronic wound the most according to claim 3, it is characterised in that: described oil immersion liquid
Preparation method is as follows: weighting raw materials, takes 1500ml olive oil and is heated to 120 DEG C-150 DEG C and puts into Flos Carthami, keeps this temperature, treat
Flos Carthami is decocted to sallow, filters, and retains filtrate, inserts Olibanum, Myrrha, and stirring is cooled to 50 DEG C-80 DEG C, inserts Sanguis Draxonis, Moschus, ice
Sheet, stirs natural cooling, places 24 hours and filters standby.
A kind of Chinese medicine composition treating chronic wound the most according to claim 3, it is characterised in that: described hydrocolloid
Preparation method is as follows: weighting raw materials, extracts original liquid with liquid-solid extraction method from crude drug, using ethanol as Extraction solvent,
1.5 hours extraction times, Extracting temperature 60 DEG C, volume fraction of ethanol 60%, crude drug and weight ratio 1:30 of ethanol, extract
Original liquid, then mixes original liquid by weight 30-45:100 with Carboxymethyl cellulose sodium, pectin or gelatin, is prepared as water
Dissolubility hydrocolloid.
A kind of Chinese medicine composition treating chronic wound the most according to claim 3, it is characterised in that: described containing drug solns
Preparation method as follows: from crude drug, extract original liquid with liquid-solid extraction method, using ethanol as Extraction solvent, extraction time
1.5 hours, Extracting temperature 60 DEG C, volume fraction of ethanol 60%, crude drug and weight ratio 1:30 of ethanol, extract to obtain original liquid,
Then it is arranged to containing the pharmaceutical extraction thing solution that concentration is 30-45wt% with sterilized water.
7. according to the answering in preparation treatment treatment chronic wound medicine of the Chinese medicine composition described in any one of claim 1-6
With.
Application the most according to claim 7, it is characterised in that: described Chinese medicine composition is made oil immersion liquid, hydrocolloid or
After drug solns, infiltrate or be coated on alginate fabric, being prepared as pastille dressing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610651331.0A CN106138569B (en) | 2016-08-10 | 2016-08-10 | Traditional Chinese medicine composition for treating chronic wound and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201610651331.0A CN106138569B (en) | 2016-08-10 | 2016-08-10 | Traditional Chinese medicine composition for treating chronic wound and application thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107349335A (en) * | 2017-06-13 | 2017-11-17 | 吉林省拓华生物科技有限公司 | One kind carries medicine membrane film and its production and use |
| CN109010570A (en) * | 2018-09-03 | 2018-12-18 | 李宗涛 | A kind of band bed sore ointment for treating bedsore |
| CN112274562A (en) * | 2020-12-01 | 2021-01-29 | 闫恪玉 | Formula for relieving swelling and pain |
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| CN1439413A (en) * | 2003-03-26 | 2003-09-03 | 彭德生 | Chinese medicine against skin and external diseases |
| CN101112480A (en) * | 2007-08-15 | 2008-01-30 | 关瑞峰 | Golden powder for treating wound |
| CN101428122A (en) * | 2008-12-10 | 2009-05-13 | 李金梅 | Traditional Chinese medicine powder for removing necrotic tissue and promoting granulation and preparation method thereof |
| CN101791364A (en) * | 2010-04-28 | 2010-08-04 | 董崇孝 | Traditional Chinese medicine composition capable of promoting wound healing and preparation method thereof |
| CN102240354A (en) * | 2011-06-20 | 2011-11-16 | 张佑强 | Chinese medicine prescription for treating skin ulcer and preparation method thereof |
| CN104721445A (en) * | 2015-04-01 | 2015-06-24 | 张金学 | Traditional Chinese medicine ointment for treating bedsores and preparation method thereof |
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Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1439413A (en) * | 2003-03-26 | 2003-09-03 | 彭德生 | Chinese medicine against skin and external diseases |
| CN101112480A (en) * | 2007-08-15 | 2008-01-30 | 关瑞峰 | Golden powder for treating wound |
| CN101428122A (en) * | 2008-12-10 | 2009-05-13 | 李金梅 | Traditional Chinese medicine powder for removing necrotic tissue and promoting granulation and preparation method thereof |
| CN101791364A (en) * | 2010-04-28 | 2010-08-04 | 董崇孝 | Traditional Chinese medicine composition capable of promoting wound healing and preparation method thereof |
| CN102240354A (en) * | 2011-06-20 | 2011-11-16 | 张佑强 | Chinese medicine prescription for treating skin ulcer and preparation method thereof |
| CN104721445A (en) * | 2015-04-01 | 2015-06-24 | 张金学 | Traditional Chinese medicine ointment for treating bedsores and preparation method thereof |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107349335A (en) * | 2017-06-13 | 2017-11-17 | 吉林省拓华生物科技有限公司 | One kind carries medicine membrane film and its production and use |
| CN109010570A (en) * | 2018-09-03 | 2018-12-18 | 李宗涛 | A kind of band bed sore ointment for treating bedsore |
| CN112274562A (en) * | 2020-12-01 | 2021-01-29 | 闫恪玉 | Formula for relieving swelling and pain |
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| CN106138569B (en) | 2020-07-31 |
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