CN105996035A - Fishbone, dried small shrimp, radix angelica sinensis and dried orange peel chewable tablets capable of enriching calcium and preparation method of fishbone, dried small shrimp, radix angelica sinensis and dried orange peel chewable tablets - Google Patents
Fishbone, dried small shrimp, radix angelica sinensis and dried orange peel chewable tablets capable of enriching calcium and preparation method of fishbone, dried small shrimp, radix angelica sinensis and dried orange peel chewable tablets Download PDFInfo
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- CN105996035A CN105996035A CN201610371740.5A CN201610371740A CN105996035A CN 105996035 A CN105996035 A CN 105996035A CN 201610371740 A CN201610371740 A CN 201610371740A CN 105996035 A CN105996035 A CN 105996035A
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- 239000007910 chewable tablet Substances 0.000 title claims abstract description 26
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 title claims abstract description 15
- 239000011575 calcium Substances 0.000 title claims abstract description 15
- 229910052791 calcium Inorganic materials 0.000 title claims abstract description 15
- 238000002360 preparation method Methods 0.000 title claims description 7
- 241000382455 Angelica sinensis Species 0.000 title abstract 7
- 241000238557 Decapoda Species 0.000 title abstract 5
- 239000000843 powder Substances 0.000 claims abstract description 23
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims abstract description 14
- 229920001661 Chitosan Polymers 0.000 claims abstract description 13
- 239000004005 microsphere Substances 0.000 claims abstract description 8
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims abstract description 7
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims abstract description 7
- 240000001008 Dimocarpus longan Species 0.000 claims abstract description 7
- 235000000235 Euphoria longan Nutrition 0.000 claims abstract description 7
- 229930195725 Mannitol Natural products 0.000 claims abstract description 7
- 229940087559 grape seed Drugs 0.000 claims abstract description 7
- 235000019359 magnesium stearate Nutrition 0.000 claims abstract description 7
- 239000000594 mannitol Substances 0.000 claims abstract description 7
- 235000010355 mannitol Nutrition 0.000 claims abstract description 7
- 229940100486 rice starch Drugs 0.000 claims abstract description 7
- 235000010413 sodium alginate Nutrition 0.000 claims abstract description 7
- 239000000661 sodium alginate Substances 0.000 claims abstract description 7
- 229940005550 sodium alginate Drugs 0.000 claims abstract description 7
- 239000002994 raw material Substances 0.000 claims abstract description 4
- 241000125175 Angelica Species 0.000 claims description 35
- 235000001287 Guettarda speciosa Nutrition 0.000 claims description 34
- 241000143060 Americamysis bahia Species 0.000 claims description 19
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 18
- 229940068682 chewable tablet Drugs 0.000 claims description 16
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 15
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 9
- 238000001914 filtration Methods 0.000 claims description 9
- 239000000203 mixture Substances 0.000 claims description 9
- 239000011324 bead Substances 0.000 claims description 6
- 210000000582 semen Anatomy 0.000 claims description 6
- 239000007779 soft material Substances 0.000 claims description 6
- 238000003756 stirring Methods 0.000 claims description 6
- 230000001105 regulatory effect Effects 0.000 claims description 5
- 238000000855 fermentation Methods 0.000 claims description 4
- 230000004151 fermentation Effects 0.000 claims description 4
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims description 3
- 240000001046 Lactobacillus acidophilus Species 0.000 claims description 3
- 235000013956 Lactobacillus acidophilus Nutrition 0.000 claims description 3
- 239000001888 Peptone Substances 0.000 claims description 3
- 108010080698 Peptones Proteins 0.000 claims description 3
- 230000033228 biological regulation Effects 0.000 claims description 3
- 238000004132 cross linking Methods 0.000 claims description 3
- 239000000706 filtrate Substances 0.000 claims description 3
- 238000000227 grinding Methods 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- 235000019319 peptone Nutrition 0.000 claims description 3
- 238000001694 spray drying Methods 0.000 claims description 3
- 230000001954 sterilising effect Effects 0.000 claims description 3
- 238000004659 sterilization and disinfection Methods 0.000 claims description 3
- 239000006228 supernatant Substances 0.000 claims description 3
- 238000001291 vacuum drying Methods 0.000 claims description 3
- 238000005406 washing Methods 0.000 claims description 3
- 210000004369 blood Anatomy 0.000 abstract description 10
- 239000008280 blood Substances 0.000 abstract description 10
- 208000007502 anemia Diseases 0.000 abstract description 7
- 230000000694 effects Effects 0.000 abstract description 6
- 230000006378 damage Effects 0.000 abstract description 4
- 230000000857 drug effect Effects 0.000 abstract description 2
- 208000024891 symptom Diseases 0.000 abstract description 2
- 241000251468 Actinopterygii Species 0.000 abstract 1
- 240000007087 Apium graveolens Species 0.000 abstract 1
- 235000015849 Apium graveolens Dulce Group Nutrition 0.000 abstract 1
- 235000010591 Appio Nutrition 0.000 abstract 1
- 244000141359 Malus pumila Species 0.000 abstract 1
- 241000899834 Obovaria olivaria Species 0.000 abstract 1
- 241000220317 Rosa Species 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 235000021016 apples Nutrition 0.000 abstract 1
- 229940036811 bone meal Drugs 0.000 abstract 1
- 239000002374 bone meal Substances 0.000 abstract 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 4
- 206010010774 Constipation Diseases 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 210000003743 erythrocyte Anatomy 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 210000000952 spleen Anatomy 0.000 description 2
- 201000000736 Amenorrhea Diseases 0.000 description 1
- 206010001928 Amenorrhoea Diseases 0.000 description 1
- 208000006820 Arthralgia Diseases 0.000 description 1
- 208000005171 Dysmenorrhea Diseases 0.000 description 1
- 206010013935 Dysmenorrhoea Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 208000019255 Menstrual disease Diseases 0.000 description 1
- QYZBCWXZSYTIOY-UHFFFAOYSA-N Mercuric oxide Chemical compound [O-2].[Hg+2] QYZBCWXZSYTIOY-UHFFFAOYSA-N 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 208000001132 Osteoporosis Diseases 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 241000590428 Panacea Species 0.000 description 1
- 208000025747 Rheumatic disease Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000002776 aggregation Effects 0.000 description 1
- 238000004220 aggregation Methods 0.000 description 1
- 231100000540 amenorrhea Toxicity 0.000 description 1
- 206010003549 asthenia Diseases 0.000 description 1
- 230000023555 blood coagulation Effects 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 235000008935 nutritious Nutrition 0.000 description 1
- 210000005259 peripheral blood Anatomy 0.000 description 1
- 239000011886 peripheral blood Substances 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000003014 reinforcing effect Effects 0.000 description 1
- 230000000552 rheumatic effect Effects 0.000 description 1
- 230000035943 smell Effects 0.000 description 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/113—Acidophilus
Landscapes
- Medicinal Preparation (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The invention discloses fishbone, dried small shrimp, radix angelica sinensis and dried orange peel chewable tablets capable of enriching calcium. The fishbone, dried small shrimp, radix angelica sinensis and dried orange peel chewable tablets are prepared from the following raw materials in parts by weight: 60-70 parts of radix angelica sinensis, 20-25 parts of dried orange peel, 10-15 parts of fish bone meal, 12-14 parts of dried small shrimp powder, 1-2 parts of grape seed submicron powder, 15-16 parts of celery, 14-17 parts of apples, 2-4 parts of hickory nut kernels, 20-25 parts of purple rice starch, 4-6 parts of dried longan pulp dry powder, 2-4 parts of rose flavored juice, 8-10 parts of mannitol, 6-8 parts of magnesium stearate, 50-60 parts of chitosan, and an appropriate quantity of a sodium alginate solution. The radix angelica sinensis and the dried orange peel are combined to make the chewable tablets, so that the chewable tablets have a good effect of replenishing blood, crowds suffering from anemia can eat the chewable tablets when anemia symptoms occur, and damage caused by anemia is reduced; the radix angelica sinensis and the dried orange peel are fermented to make ferments, so that drug effects can be strengthened, and rapid absorption is facilitated. The chewable tablets are wrapped in microspheres, so that pungent smell and pungent mouth feel of the chewable tablets can be effectively concealed, and the chewable tablets are convenient to eat.
Description
Technical field
The present invention relates to food processing technology field, particularly relate to a kind of fishbone dried small shrimps and replenish the calcium angelica and dried orange peel chewable tablet and preparation method thereof.
Background technology
Radix Angelicae Sinensis, for the dry root of umbelliferae angelica.Main product the southeast of Gansu, is secondly that Yunnan, Sichuan, Shaanxi, Hubei etc. save, is cultivation.There is replenishing and activating blood, menstruction regulating and pain relieving, effect of loosening bowel to relieve constipation.It is usually used in blood deficiency and yellow complexion, dizziness cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores, dryness of the intestine constipation.Radix Angelicae Sinensis weighs due to its sweet in the mouth, therefore specially can enrich blood, and its gas is light and pungent, thus again can promoting the circulation of blood, invigorating middle warmer has, has benefit in row, is the panacea enriched blood of circulation of qi promoting.
Pericarpium Citri Reticulatae is conventional Chinese medicine, has regulating qi-flowing for strengthening spleen, the function of drying dampness to eliminate phlegm.Ming Dynasty's Li Shizhen (1518-1593 A.D.) cloud: " then mend with tonic, then rush down with cathartic, then rise with Hydrargyri Oxydum Rubrum, then drop with fall medicine.Spleen is the mother of Primordial Qi, is the label taking the photograph gas, therefore Pericarpium Citri tangerinae is two through the medicine of edema caused by disorder of QI, but with join and reinforcing and reducing lift also." Pericarpium Citri Reticulatae can significantly reduce blood fat, significantly alleviates hepatocellular esterified degree, there are obvious blood fat reducing, prevention of arterial hardening and anti-high blood coagulation state effect, and Pericarpium Citri Reticulatae can suppress platelet aggregation, and there is reduction erythrocyte aggregation.
Anemia refers to that human peripheral blood erythrocyte volume reduces, less than a kind of common clinical symptoms of lower limit normal range.Pericarpium Citri Reticulatae and Radix Angelicae Sinensis collocation have effect of well enriching blood, and daily can have some improvement anemia.But owing to inconvenience taken by Chinese medicine, need to be processed making it easy to carry and take to them.The chewable tablet occurred on market can meet requirement, therefore they can be made chewable tablet, the most easy to carry, conveniently takes, and can quantitatively take, it is to avoid disposably takes and damage human body too much.
Summary of the invention
The object of the invention is contemplated to make up the defect of prior art, it is provided that a kind of fishbone dried small shrimps is replenished the calcium angelica and dried orange peel chewable tablet and preparation method thereof.
The present invention is achieved by the following technical solutions:
A kind of fishbone dried small shrimps is replenished the calcium angelica and dried orange peel chewable tablet, is made up of the raw material of following weight portion: Radix Angelicae Sinensis 60-70, Pericarpium Citri Reticulatae 20-25, fishbone powder 10-15, dried small shrimps powder 12-14, grape seed ultramicro-farina 1-2, Herba Apii graveolentis 15-16, Fructus Mali pumilae 14-17, Semen Caryae Cathayensis 2-4, purple rice starch 20-25, Arillus Longan dry powder 4-6, Liquor Rosae Rugosae Distillata 2-4, mannitol 8-10, magnesium stearate 6-8, chitosan 50-60, sodium alginate soln are appropriate.
Described a kind of fishbone dried small shrimps is replenished the calcium the preparation method of angelica and dried orange peel chewable tablet, comprises the following steps:
(1) the soak by water 60-70min of 5-6 times is added after Radix Angelicae Sinensis, Pericarpium Citri Reticulatae being cleaned together, after filtration, medicinal residues are pulverized standby, filtrate adds ethanol stirring after being concentrated into the 20-30% of volume be 65-70% to alcohol content, take supernatant after standing 20-24h and reclaim ethanol, after spray drying, obtain angelica and dried orange peel water extract；
(2) it is ground into 40-50 mesh after draining moisture after Herba Apii graveolentis, Fructus Mali pumilae, Semen Caryae Cathayensis being cleaned roguing, the water of the weight such as addition and the peptone of 2-3%, through 110-120 DEG C of autoclave sterilization 25-30min, then first regulating mixture pH after being cooled to 35-37 DEG C is 5.5-6, then the bacillus acidophilus after overactivation accessing 4-5% is fermented 20-25h, then the medicinal residues adding angelica and dried orange peel continue fermentation 8-12h, and dried ultramicronising is pulverized and obtained angelica and dried orange peel ferment；
(3) add chitosan in 1% acetum of certain mass and dissolve, then with after sodium hydroxide solution regulation pH to 6.0, obtain chitosan solution standby, angelica and dried orange peel ferment is added in the sodium alginate soln of appropriate 15g/L and dissolve, it is then added in certain density calcium chloride solution, continuously stirred 25-30min, bead is collected after filtration, bead is put in chitosan solution, continuously stirred crosslinking 50-60min, at a temperature of 40 DEG C, it is dried 20-24h after sucking filtration washing, obtains angelica and dried orange peel ferment microsphere；
(4) angelica and dried orange peel ferment microsphere, the water extract of angelica and dried orange peel, fishbone powder, dried small shrimps powder, grape seed ultramicro-farina, purple rice starch, Arillus Longan dry powder, Liquor Rosae Rugosae Distillata, mannitol co-grinding are crossed 60 mesh sieves, it is subsequently adding the water of 10% weight portion, stir and be placed in the vacuum drying oven of 55-65 DEG C that to be dried to water content be 2.5-3.5%, obtain mixing soft material；
(5) will mix after soft material is pulverized and cross 14-18 mesh sieve, and be subsequently adding magnesium stearate, after mix homogeneously, carry out tabletting, and obtain fishbone dried small shrimps and replenish the calcium angelica and dried orange peel chewable tablet.
The invention have the advantage that the present invention is by making chewable tablet and have, by Radix Angelicae Sinensis and Pericarpium Citri Reticulatae combination, effect of well enriching blood, anemia crowd can be made conveniently to take when Anemia, reduce its harm brought, angelica and dried orange peel is made ferment by fermentation and can strengthen drug effect, contribute to quickly absorbing, it is wrapped in microsphere and can effectively be covered its irritating abnormal smells from the patient and mouthfeel, be conducive to taking.The fishbone powder of interpolation, dried small shrimps powder etc. are the most nutritious, improve the shortcoming that chewable tablet nutrition is single, but also have good effect of supplemented calcium, effective to sufferers of osteoporosis face.
Detailed description of the invention
A kind of fishbone dried small shrimps is replenished the calcium angelica and dried orange peel chewable tablet, is made up of the raw material of following weight portion (kg): Radix Angelicae Sinensis 60, Pericarpium Citri Reticulatae 20, fishbone powder 10, dried small shrimps powder 12, grape seed ultramicro-farina 1, Herba Apii graveolentis 15, Fructus Mali pumilae 14, Semen Caryae Cathayensis 2, purple rice starch 20, Arillus Longan dry powder 4, Liquor Rosae Rugosae Distillata 2, mannitol 8, magnesium stearate 6, chitosan 50, sodium alginate soln are appropriate.
Described a kind of fishbone dried small shrimps is replenished the calcium the preparation method of angelica and dried orange peel chewable tablet, comprises the following steps:
(1) the soak by water 60min of 5 times is added after Radix Angelicae Sinensis, Pericarpium Citri Reticulatae being cleaned together, after filtration, medicinal residues are pulverized standby, filtrate be concentrated into volume 20% after to add ethanol stirring be 65% to alcohol content, stand and take supernatant after 20h and reclaim ethanol, after spray drying, obtain angelica and dried orange peel water extract；
(2) it is ground into 40 mesh after draining moisture after Herba Apii graveolentis, Fructus Mali pumilae, Semen Caryae Cathayensis being cleaned roguing, the water of the weight such as addition and the peptone of 2%, through 110 DEG C of autoclave sterilization 25min, then first regulating mixture pH after being cooled to 35 DEG C is 5.5, then access the bacillus acidophilus after overactivation of 4% to ferment 20h, then the medicinal residues adding angelica and dried orange peel continue fermentation 8h, and dried ultramicronising is pulverized and obtained angelica and dried orange peel ferment；
(3) add chitosan in 1% acetum of certain mass and dissolve, then with after sodium hydroxide solution regulation pH to 6.0, obtain chitosan solution standby, angelica and dried orange peel ferment is added in the sodium alginate soln of appropriate 15g/L and dissolve, it is then added in certain density calcium chloride solution, continuously stirred 25min, bead is collected after filtration, bead is put in chitosan solution, continuously stirred crosslinking 50min, at a temperature of 40 DEG C, it is dried 20h after sucking filtration washing, obtains angelica and dried orange peel ferment microsphere；
(4) angelica and dried orange peel ferment microsphere, the water extract of angelica and dried orange peel, fishbone powder, dried small shrimps powder, grape seed ultramicro-farina, purple rice starch, Arillus Longan dry powder, Liquor Rosae Rugosae Distillata, mannitol co-grinding are crossed 60 mesh sieves, it is subsequently adding the water of 10% weight portion, stir and be placed in the vacuum drying oven of 55 DEG C that to be dried to water content be 2.5%, obtain mixing soft material；
(5) will mix after soft material is pulverized and cross 14 mesh sieves, and be subsequently adding magnesium stearate, after mix homogeneously, carry out tabletting, and obtain fishbone dried small shrimps and replenish the calcium angelica and dried orange peel chewable tablet.
Claims (2)
1. a fishbone dried small shrimps is replenished the calcium angelica and dried orange peel chewable tablet, it is characterized in that, be made up of the raw material of following weight portion: Radix Angelicae Sinensis 60-70, Pericarpium Citri Reticulatae 20-25, fishbone powder 10-15, dried small shrimps powder 12-14, grape seed ultramicro-farina 1-2, Herba Apii graveolentis 15-16, Fructus Mali pumilae 14-17, Semen Caryae Cathayensis 2-4, purple rice starch 20-25, Arillus Longan dry powder 4-6, Liquor Rosae Rugosae Distillata 2-4, mannitol 8-10, magnesium stearate 6-8, chitosan 50-60, sodium alginate soln are appropriate.
A kind of fishbone dried small shrimps the most according to claim 1 is replenished the calcium the preparation method of angelica and dried orange peel chewable tablet, it is characterised in that comprise the following steps:
(1) the soak by water 60-70min of 5-6 times is added after Radix Angelicae Sinensis, Pericarpium Citri Reticulatae being cleaned together, after filtration, medicinal residues are pulverized standby, filtrate adds ethanol stirring after being concentrated into the 20-30% of volume be 65-70% to alcohol content, take supernatant after standing 20-24h and reclaim ethanol, after spray drying, obtain angelica and dried orange peel water extract；
(2) it is ground into 40-50 mesh after draining moisture after Herba Apii graveolentis, Fructus Mali pumilae, Semen Caryae Cathayensis being cleaned roguing, the water of the weight such as addition and the peptone of 2-3%, through 110-120 DEG C of autoclave sterilization 25-30min, then first regulating mixture pH after being cooled to 35-37 DEG C is 5.5-6, then the bacillus acidophilus after overactivation accessing 4-5% is fermented 20-25h, then the medicinal residues adding angelica and dried orange peel continue fermentation 8-12h, and dried ultramicronising is pulverized and obtained angelica and dried orange peel ferment；
(3) add chitosan in 1% acetum of certain mass and dissolve, then with after sodium hydroxide solution regulation pH to 6.0, obtain chitosan solution standby, angelica and dried orange peel ferment is added in the sodium alginate soln of appropriate 15g/L and dissolve, it is then added in certain density calcium chloride solution, continuously stirred 25-30min, bead is collected after filtration, bead is put in chitosan solution, continuously stirred crosslinking 50-60min, at a temperature of 40 DEG C, it is dried 20-24h after sucking filtration washing, obtains angelica and dried orange peel ferment microsphere；
(4) angelica and dried orange peel ferment microsphere, the water extract of angelica and dried orange peel, fishbone powder, dried small shrimps powder, grape seed ultramicro-farina, purple rice starch, Arillus Longan dry powder, Liquor Rosae Rugosae Distillata, mannitol co-grinding are crossed 60 mesh sieves, it is subsequently adding the water of 10% weight portion, stir and be placed in the vacuum drying oven of 55-65 DEG C that to be dried to water content be 2.5-3.5%, obtain mixing soft material；
(5) will mix after soft material is pulverized and cross 14-18 mesh sieve, and be subsequently adding magnesium stearate, after mix homogeneously, carry out tabletting, and obtain fishbone dried small shrimps and replenish the calcium angelica and dried orange peel chewable tablet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610371740.5A CN105996035A (en) | 2016-05-31 | 2016-05-31 | Fishbone, dried small shrimp, radix angelica sinensis and dried orange peel chewable tablets capable of enriching calcium and preparation method of fishbone, dried small shrimp, radix angelica sinensis and dried orange peel chewable tablets |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610371740.5A CN105996035A (en) | 2016-05-31 | 2016-05-31 | Fishbone, dried small shrimp, radix angelica sinensis and dried orange peel chewable tablets capable of enriching calcium and preparation method of fishbone, dried small shrimp, radix angelica sinensis and dried orange peel chewable tablets |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105996035A true CN105996035A (en) | 2016-10-12 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610371740.5A Withdrawn CN105996035A (en) | 2016-05-31 | 2016-05-31 | Fishbone, dried small shrimp, radix angelica sinensis and dried orange peel chewable tablets capable of enriching calcium and preparation method of fishbone, dried small shrimp, radix angelica sinensis and dried orange peel chewable tablets |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105996035A (en) |
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2016
- 2016-05-31 CN CN201610371740.5A patent/CN105996035A/en not_active Withdrawn
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Application publication date: 20161012 |
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