CN105963597A - 一种治疗口腔溃疡的中药 - Google Patents

一种治疗口腔溃疡的中药 Download PDF

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CN105963597A
CN105963597A CN201610355851.7A CN201610355851A CN105963597A CN 105963597 A CN105963597 A CN 105963597A CN 201610355851 A CN201610355851 A CN 201610355851A CN 105963597 A CN105963597 A CN 105963597A
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严伟健
姚增科
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Abstract

本发明涉及一种治疗口腔溃疡的中药，由以下质量份数的组分组成：黄连14～18份、鸡内金16～20份、穿心莲12～16份、笔筒草10～14份、鱼眼草根16～20份、霞草12～16份、马兰10～14份、仙鹤草16～20份、茵陈12～16份、柴胡10～14份、千屈菜16～20份、崩大碗12～16份、合欢花12～16份、紫草10～14份、百部16～20份、棉花灰12～16份、玉竹10～14份、山茱萸16～20份、四季青12～16份、羊蹄草10～14份、枫香脂16～20份、土贝母12～16份、白茅根10～14份、积雪草16～20份、双花12～16份、翼首草12～16份、龙胆草12～16份、车前草12～16份、半枝莲12～16份。本方能清热解毒，清热化湿，活血消炎，扶正法邪，诸药配合，对口腔溃疡具有较好治疗效果。

Description

一种治疗口腔溃疡的中药
技术领域
本发明涉及一种治疗口腔溃疡的中药，属于中药配方技术领域。
背景技术
口腔溃疡是一种常见的发生于口腔黏膜的溃疡性损伤病症，多见于唇内侧、舌头、舌腹、颊黏膜、前庭沟、软腭等部位，这些部位的黏膜缺乏角质化层或角化较差。舌头溃疡指发生于舌头、舌腹部位的口腔溃疡。口腔溃疡发作时疼痛剧烈，局部灼痛明显，严重者还会影响饮食、说话，对日常生活造成极大不便；可并发口臭、慢性咽炎、便秘、头痛、头晕、恶心、乏力、烦躁、发热、淋巴结肿大等全身症状。
发明内容
本发明的目的在于提供一种治疗口腔溃疡的中药，以便更好地针对口腔溃疡进行治疗。
为了实现上述目的，本发明的技术方案如下。
一种治疗口腔溃疡的中药，由以下质量份数的组分组成：黄连14～18份、鸡内金16～20份、穿心莲12～16份、笔筒草10～14份、鱼眼草根16～20份、霞草12～16份、马兰10～14份、仙鹤草16～20份、茵陈12～16份、柴胡10～14份、千屈菜16～20份、崩大碗12～16份、合欢花12～16份、紫草10～14份、百部16～20份、棉花灰12～16份、玉竹10～14份、山茱萸16～20份、四季青12～16份、羊蹄草10～14份、枫香脂16～20份、土贝母12～16份、白茅根10～14份、积雪草16～20份、双花12～16份、翼首草12～16份、龙胆草12～16份、车前草12～16份、半枝莲12～16份。
进一步地，上述治疗口腔溃疡的中药，由以下质量份数的组分组成：黄连14份、鸡内金16份、穿心莲12份、笔筒草10份、鱼眼草根16份、霞草12份、马兰10份、仙鹤草16份、茵陈12份、柴胡10份、千屈菜16份、崩大碗12份、合欢花12份、紫草10份、百部16份、棉花灰12份、玉竹10份、山茱萸16份、四季青12份、羊蹄草10份、枫香脂16份、土贝母12份、白茅根10份、积雪草16份、双花12份、翼首草12份、龙胆草12份、车前草12份、半枝莲12份。
进一步地，上述治疗口腔溃疡的中药，由以下质量份数的组分组成：黄连16份、鸡内金18份、穿心莲14份、笔筒草12份、鱼眼草根18份、霞草14份、马兰12份、仙鹤草18份、茵陈14份、柴胡12份、千屈菜18份、崩大碗14份、合欢花14份、紫草12份、百部18份、棉花灰14份、玉竹12份、山茱萸18份、四季青14份、羊蹄草12份、枫香脂18份、土贝母14份、白茅根12份、积雪草18份、双花14份、翼首草14份、龙胆草14份、车前草14份、半枝莲14份。
进一步地，上述治疗口腔溃疡的中药，由以下质量份数的组分组成：黄连18份、鸡内金20份、穿心莲16份、笔筒草14份、鱼眼草根20份、霞草16份、马兰14份、仙鹤草20份、茵陈16份、柴胡14份、千屈菜20份、崩大碗16份、合欢花16份、紫草14份、百部20份、棉花灰16份、玉竹14份、山茱萸20份、四季青16份、羊蹄草14份、枫香脂20份、土贝母16份、白茅根14份、积雪草20份、双花16份、翼首草16份、龙胆草16份、车前草16份、半枝莲16份。
本方能清热解毒，清热化湿，活血消炎，扶正法邪，诸药配合，对口腔溃疡具有较好治疗效果，临床用之每收佳效。三年中，通过对39名患者的使用表明，该药能有效治疗口腔溃疡，有效率达92.31％。
下面结合临床实验数据说明本发明的有益效果：
1、一般资料：发明人2012年11月-2015年12月间共收集了78例口腔溃疡患者，其中，年龄20岁～50岁，病情1个月～3个月。随机分为：治疗组39例，对照组39例。两组年龄等资料无显著性差异，具有可比性。
2、试验方法：(1)对照组服用某市售口腔溃疡散，按照说明书服用。疗程14天。(2)治疗组口服本发明按照具体实施例2制得的散剂，早、中、晚各一次。疗程14天。(3)疗效标准及治疗结果：疗效标准：痊愈：口腔溃疡的临床症状全部消失。好转：口腔溃疡的临床症状减轻，病情得到控制。无效：口腔溃疡的临床症状无明显好转或加重。以痊愈和好转计算有效率。治疗统计结果见表1。
表1两组疗效比较
由此可见，采用本发明的组方制得的药物能够安全有效治疗口腔溃疡。
毒性试验：
试验药品是本发明实施例2中的散剂。试验动物为ICR种小白鼠，体重18～22克，雌雄各半，共40只。试验方法是，禁食12小时后，按20克/千克给小白鼠灌胃4个月，长期毒性试验结果显示，小白鼠体重，肝、肾功能、血象等与对照组无明显差异，表明该药的安全性大，属于无毒级别。
具体实施方式
下面结合实施例对本发明的具体实施方式进行描述，以便更好的理解本发明。
实施例1
本实施例中的治疗口腔溃疡的中药，称取黄连14克、鸡内金16克、穿心莲12克、笔筒草10克、鱼眼草根16克、霞草12克、马兰10克、仙鹤草16克、茵陈12克、柴胡10克、千屈菜16克、崩大碗12克、合欢花12克、紫草10克、百部16克、棉花灰12克、玉竹10克、山茱萸16克、四季青12克、羊蹄草10克、枫香脂16克、土贝母12克、白茅根10克、积雪草16克、双花12克、翼首草12克、龙胆草12克、车前草12克、半枝莲12克。加6倍量水，煎煮2小时，过滤；滤渣加8倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，混合均匀，装入胶囊壳，即得符合治疗用1天用量的胶囊剂。用于治疗口腔溃疡，口服，每日分早、中、晚三次服用。
实施例2
本实施例中的治疗口腔溃疡的中药，称取黄连16克、鸡内金18克、穿心莲14克、笔筒草12克、鱼眼草根18克、霞草14克、马兰12克、仙鹤草18克、茵陈14克、柴胡12克、千屈菜18克、崩大碗14克、合欢花14克、紫草12克、百部18克、棉花灰14克、玉竹12克、山茱萸18克、四季青14克、羊蹄草12克、枫香脂18克、土贝母14克、白茅根12克、积雪草18克、双花14克、翼首草14克、龙胆草14克、车前草14克、半枝莲14克。加10倍量水，煎煮2小时，过滤；滤渣加8倍量水，煎煮1.5小时，过滤；合并滤液，浓缩，干燥，合均匀，包装，即得符合治疗用1天用量的散剂。用于治疗口腔溃疡，口服，每日分早、中、晚三次服用。
实施例3
本实施例中的治疗口腔溃疡的中药，称取黄连18克、鸡内金20克、穿心莲16克、笔筒草14克、鱼眼草根20克、霞草16克、马兰14克、仙鹤草20克、茵陈16克、柴胡14克、千屈菜20克、崩大碗16克、合欢花16克、紫草14克、百部20克、棉花灰16克、玉竹14克、山茱萸20克、四季青16克、羊蹄草14克、枫香脂20克、土贝母16克、白茅根14克、积雪草20克、双花16克、翼首草16克、龙胆草16克、车前草16克、半枝莲16克。加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，混合均匀，按照本领域常规工艺制粒，包装，即得符合治疗用1天用量的颗粒剂。用于治疗口腔溃疡，口服，每日分早、中、晚三次服用。
以上所述是本发明的优选实施方式，应当指出，对于本技术领域的普通技术人员来说，在不脱离本发明原理的前提下，还可以做出若干改进和润饰，这些改进和润饰也视为本发明的保护范围。

Claims (4)

1.一种治疗口腔溃疡的中药，其特征在于：由以下质量份数的组分组成：黄连14～18份、鸡内金16～20份、穿心莲12～16份、笔筒草10～14份、鱼眼草根16～20份、霞草12～16份、马兰10～14份、仙鹤草16～20份、茵陈12～16份、柴胡10～14份、千屈菜16～20份、崩大碗12～16份、合欢花12～16份、紫草10～14份、百部16～20份、棉花灰12～16份、玉竹10～14份、山茱萸16～20份、四季青12～16份、羊蹄草10～14份、枫香脂16～20份、土贝母12～16份、白茅根10～14份、积雪草16～20份、双花12～16份、翼首草12～16份、龙胆草12～16份、车前草12～16份、半枝莲12～16份。
2.根据权利要求1所述的治疗口腔溃疡的中药，其特征在于：所述中药由以下质量份数的组分组成：黄连14份、鸡内金16份、穿心莲12份、笔筒草10份、鱼眼草根16份、霞草12份、马兰10份、仙鹤草16份、茵陈12份、柴胡10份、千屈菜16份、崩大碗12份、合欢花12份、紫草10份、百部16份、棉花灰12份、玉竹10份、山茱萸16份、四季青12份、羊蹄草10份、枫香脂16份、土贝母12份、白茅根10份、积雪草16份、双花12份、翼首草12份、龙胆草12份、车前草12份、半枝莲12份。
3.根据权利要求1所述的治疗口腔溃疡的中药，其特征在于：所述中药由以下质量份数的组分组成：黄连16份、鸡内金18份、穿心莲14份、笔筒草12份、鱼眼草根18份、霞草14份、马兰12份、仙鹤草18份、茵陈14份、柴胡12份、千屈菜18份、崩大碗14份、合欢花14份、紫草12份、百部18份、棉花灰14份、玉竹12份、山茱萸18份、四季青14份、羊蹄草12份、枫香脂18份、土贝母14份、白茅根12份、积雪草18份、双花14份、翼首草14份、龙胆草14份、车前草14份、半枝莲14份。
4.根据权利要求1所述的治疗口腔溃疡的中药，其特征在于：所述中药由以下质量份数的组分组成：黄连18份、鸡内金20份、穿心莲16份、笔筒草14份、鱼眼草根20份、霞草16份、马兰14份、仙鹤草20份、茵陈16份、柴胡14份、千屈菜20份、崩大碗16份、合欢花16份、紫草14份、百部20份、棉花灰16份、玉竹14份、山茱萸20份、四季青16份、羊蹄草14份、枫香脂20份、土贝母16份、白茅根14份、积雪草20份、双花16份、翼首草16份、龙胆草16份、车前草16份、半枝莲16份。
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CN106491857A (zh) * 2016-11-29 2017-03-15 广西大学 一种治疗口腔溃疡的中药制剂及其制备方法
CN108379152A (zh) * 2018-04-16 2018-08-10 新乡医学院三全学院 一种口腔护理液及制备方法

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CN103041243A (zh) * 2013-01-29 2013-04-17 宋小冰 一种中药清火排毒祛痘胶囊

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CN103041243A (zh) * 2013-01-29 2013-04-17 宋小冰 一种中药清火排毒祛痘胶囊

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106491857A (zh) * 2016-11-29 2017-03-15 广西大学 一种治疗口腔溃疡的中药制剂及其制备方法
CN108379152A (zh) * 2018-04-16 2018-08-10 新乡医学院三全学院 一种口腔护理液及制备方法

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