CN105943855A - 一种治疗病毒性心肌炎的中药组合物 - Google Patents

一种治疗病毒性心肌炎的中药组合物 Download PDF

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CN105943855A
CN105943855A CN201610345612.3A CN201610345612A CN105943855A CN 105943855 A CN105943855 A CN 105943855A CN 201610345612 A CN201610345612 A CN 201610345612A CN 105943855 A CN105943855 A CN 105943855A
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董伟
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Abstract

本发明涉及一种治疗病毒性心肌炎的中药组合物，其中药原料及重量份配比为：黄芪10‑30份、水红花子5‑25份、罗布麻5‑20份、麦冬5‑25份、石龙刍5‑25份、茶树根5‑25份、昙花5‑25份、荜茇5‑20份、刺龙牙5‑25份、薄荷5‑25份、柏子仁5‑25份、葶苈子5‑20份、血风藤5‑25份、龙眼肉5‑25份、乌金草5‑20份、马鞭草5‑25份、回心草5‑25份、绢毛菊5‑20份、独叶岩珠5‑25份、肿节风5‑25份、瓜萎皮5‑20份、黑点草5‑25份、仙茅5‑25份、甘草5‑15份。本发明的中药组合物具有补益气血、润肺清心、清热解毒、养心安神、行气止痛、活血散瘀的功效，其治疗病毒性心肌炎疗效显著，作用可靠。

Description

一种治疗病毒性心肌炎的中药组合物
技术领域
本发明涉及一种传统草药的未确定结构的医药配制品，尤其是一种治疗病毒性心肌炎的中药组合物。
背景技术
病毒性心肌炎是指由各种病毒引起的急性或慢性心肌炎症，以儿童和40 岁以下的成年人居多。其中，35％的病人在 10-30 岁之间发病，成年人发病年龄多在31-35岁。90％左右的患者以心律失常为主诉或首见症状，常见心悸、胸闷、心前区隐痛、头晕、乏力等症状，可出现晕厥甚至阿-斯综合征，重症弥漫性心肌炎可引起急性心力衰竭，易合并心源性休克或导致心肌病。目前西医尚无特效治疗方法，临床多采用免疫抑制剂、干扰素和心肌细胞营养剂等对症治疗，其虽有一定的疗效，但存在治标不治本及副作用的不足。
祖国医学认为病毒性心肌炎多由素体正气不足、心肺阴虚，邪毒侵心所致。
根据中医理论，针对病毒性心肌炎的发病机理，采用补益气血、润肺清心、清热解毒、养心安神、行气止痛、活血散瘀的治法，进行辩证配伍组方，以达到标本兼治的目的。
发明内容
为了克服现有技术中治疗病毒性心肌炎存在治标不治本及副作用的不足，本发明提供一种配制简便、成本低、疗效显著、无副作用的治疗病毒性心肌炎的中药组合物。
本发明解决其技术问题所采用的技术方案是：一种治疗病毒性心肌炎的中药组合物，其特征在于：其中药原料及重量份配比为：黄芪10-30份、水红花子5-25份、罗布麻5-20份、麦冬5-25份、石龙刍5-25份、茶树根5-25份、昙花5-25份、荜茇5-20份、刺龙牙5-25份、薄荷5-25份、柏子仁5-25份、葶苈子5-20份、血风藤5-25份、龙眼肉5-25份、乌金草5-20份、马鞭草5-25份、回心草5-25份、绢毛菊5-20份、独叶岩珠5-25份、肿节风5-25份、瓜萎皮5-20份、黑点草5-25份、仙茅5-25份、甘草5-15份。
本发明的优选技术方案是：一种治疗病毒性心肌炎的中药组合物，其特征在于：其中药原料及重量份配比为：黄芪20份、水红花子15份、罗布麻10份、麦冬15份、石龙刍15份、茶树根15份、昙花15份、荜茇10份、刺龙牙15份、薄荷15份、柏子仁15份、葶苈子10份、血风藤15份、龙眼肉15份、乌金草10份、马鞭草15份、回心草15份、绢毛菊10份、独叶岩珠15份、肿节风15份、瓜萎皮10份、黑点草15份、仙茅15份、甘草10份。
本发明中药组合物是在传统中医理论和临床经验指导下，精选药物组方。本发明中药组合物中：黄芪具有益气固表、敛汗固脱、托疮生肌、利水消肿的功效；水红花子具有活血消积、健脾利湿、清热解毒、明目的功效；罗布麻具有清热平肝、利水消肿的功效；麦冬具有养阴生津、润肺清心的功效；石龙刍具有利水通淋、泄热、安神、凉血止血的功效；茶树根具有强心利尿、活血调经、清热解毒的功效；昙花具有清肺止咳、凉血止血、养心安神的功效；荜茇具有温中散寒、行气止痛的功效；刺龙牙具有益气补肾、祛风利湿、活血止痛的功效；薄荷具有疏散风热、清利解毒、疏肝解郁的功效；柏子仁具有养心安神、润肠通便的功效；葶苈子具有泻肺降气、祛痰平喘、利水消肿的功效；血风藤具有补益气血、祛风活络的功效；龙眼肉具有补益心脾、养血安神的功效；乌金草具有平肝阳、养心安神、养血调经的功效；马鞭草具有清热解毒、活血散瘀、利水消肿的功效；回心草具有养心安神、镇静的功效；绢毛菊具有清热解毒、凉血止血的功效；独叶岩珠具有滋阴清热、解毒消肿的功效；肿节风具有祛风除湿、活血散瘀、清热解毒的功效；瓜萎皮具有润肺化痰、利气宽胸、止血通便的功效；黑点草具有清热除烦、活血消肿的功效；仙茅具有补肾助阳、益精血、强筋骨、行血消肿的功效；甘草具有补脾益气、清热解毒、祛痰止咳、调和诸药的功效。本发明精选药物组方，其药物组分经辩证配伍，在作用上相互佐助，共奏补益气血、润肺清心、清热解毒、养心安神、行气止痛、活血散瘀的功效，对病毒性心肌炎的治疗达到标本兼治。
本发明组合物的组分均采用天然的中药原料，其配制简便、药源广、成本低。本发明遵循中医的处方用药原则，各种组分药物采用水煎服用。经临床应用验证，其疗效显著可靠，药性平和，未出现毒副作用，有效率达96.7%，治愈率73.3%。
具体实施方式
下面结合实施例对本发明作进一步说明。
实施例1
一种治疗病毒性心肌炎的中药组合物，其中药原料及重量配比为：黄芪20g、水红花子15g、罗布麻10g、麦冬15g、石龙刍15g、茶树根15g、昙花15g、荜茇10g、刺龙牙15g、薄荷15g、柏子仁15g、葶苈子10g、血风藤15g、龙眼肉15g、乌金草10g、马鞭草15g、回心草15g、绢毛菊10g、独叶岩珠15g、肿节风15g、瓜萎皮10g、黑点草15g、仙茅15g、甘草10g。
实施例2
一种治疗病毒性心肌炎的中药组合物，其中药原料及重量配比为：黄芪15g、水红花子25g、罗布麻12g、麦冬20g、石龙刍5g、茶树根25g、昙花10g、荜茇20g、刺龙牙5g、薄荷25g、柏子仁10g、葶苈子20g、血风藤5g、龙眼肉25g、乌金草12g、马鞭草20g、回心草5g、绢毛菊15g、独叶岩珠10g、肿节风20g、瓜萎皮5g、黑点草25g、仙茅10g、甘草15g。
实施例3
一种治疗病毒性心肌炎的中药组合物，其中药原料及重量配比为：黄芪25g、水红花子10g、罗布麻15g、麦冬5g、石龙刍20g、茶树根10g、昙花25g、荜茇5g、刺龙牙20g、薄荷10g、柏子仁25g、葶苈子5g、血风藤20g、龙眼肉10g、乌金草15g、马鞭草5g、回心草20g、绢毛菊12g、独叶岩珠25g、肿节风5g、瓜萎皮20g、黑点草10g、仙茅25g、甘草5g。
实施例4
一种治疗病毒性心肌炎的中药组合物，其中药原料及重量配比为：黄芪10g、水红花子20g、罗布麻5g、麦冬25g、石龙刍10g、茶树根20g、昙花5g、荜茇15g、刺龙牙10g、薄荷20g、柏子仁5g、葶苈子15g、血风藤10g、龙眼肉20g、乌金草5g、马鞭草25g、回心草10g、绢毛菊20g、独叶岩珠5g、肿节风25g、瓜萎皮12g、黑点草20g、仙茅5g、甘草8g。
实施例5
一种治疗病毒性心肌炎的中药组合物，其中药原料及重量配比为：黄芪30g、水红花子5g、罗布麻20g、麦冬10g、石龙刍25g、茶树根5g、昙花20g、荜茇12g、刺龙牙25g、薄荷5g、柏子仁20g、葶苈子12g、血风藤25g、龙眼肉5g、乌金草20g、马鞭草10g、回心草25g、绢毛菊5g、独叶岩珠20g、肿节风10g、瓜萎皮15g、黑点草5g、仙茅20g、甘草12g。
本发明实施例中的中药组合物按常规的水煎法制取药剂。具体方法如下：将组方的中药原料放入容器中，加冷水漫过药面，浸泡15～20分钟，再加水没过药面约6厘米，进行第一次煎煮，未沸前采用武火煎煮，沸后用文火煎煮20～30分钟；第二次煎煮，加水没过药面约4厘米，水沸后煎煮15～20分钟。两次煎煮取汁，合并。
本发明以实施例1所给出的一种治疗病毒性心肌炎的中药组合物，做临床疗效总结如下：
一、一般性资料：本中药组合物应用于临床观察病例60例，男34例，女26例，年龄15～45岁。
二、临床表现为：胸闷或胸隐痛、心悸怔忡、头晕、乏力气短、自汗盗汗、发热、恶心欲呕、口干饮水、关节酸痛。心脏体征有心脏扩大、心律失常心杂音、心音低钝等。
三、用法用量：临床应用时，一日一剂，水煎两遍取汁约400ml，分早、晚两次空腹温服。十天为一疗程。治疗期间忌生冷辛辣刺激之物。
四、疗效标准：
1、治愈：患者自觉心悸、胸闷、气喘等表现完全消失，心电图恢复正常，心肌酶恢复正常，心脏彩超无异常表现；
2、显效：患者自觉心悸、胸闷、气喘等表现显著减轻，心电图基本恢复正常，心肌酶恢复正常，心脏彩超无异常表现；
3、有效：患者自觉心悸、胸闷、气喘等表现减轻，心电图轻度异常，心肌酶恢复正常，心脏彩超轻度异常；
4、无效：患者自觉心悸、胸闷、气喘等表现未减轻，心电图异常未改善、心肌酶未改善，心脏彩超未改善。
五、治疗效果：该临床观察病例中，服药2-5个疗程，痊愈44例，随访未见复发；显效9例，有效5例，无效2例。治疗期间未发生毒副作用。
六、典型病例：
病例1：
马某，女，23岁。患者近期出现胸闷、乏力、气短、晕厥、自汗等症状。心电图示：频发室早，二联律。心频示：偶发室早，心肌损伤，心肌缺血。诊断为病毒性心肌炎。服用本发明中药组合物制备的药剂2个疗程胸闷、乏力、气短、晕厥、自汗等症状减轻；继续服用2个疗程后，所有症状全部消失，痊愈。
病例2：
鲍某，男，38岁。患者心悸胸闷，气短，自觉时有早搏，乏力，多梦，睡眠不实，并伴有发热、咳嗽。心电图示：频发室早，右束支不完全传导阻滞，心律不齐。诊为：病毒性心肌炎服。服用本发明中药组合物制备的药剂2个疗程，发热、咳嗽消失，心悸、胸闷、气短减轻；继续服用3个疗程，心悸、胸闷、气短等症状完全消失，心电图恢复正常，痊愈。一年后随访无复发。

Claims (2)

1.一种治疗病毒性心肌炎的中药组合物，其特征在于：其中药原料及重量份配比为：黄芪10-30份、水红花子5-25份、罗布麻5-20份、麦冬5-25份、石龙刍5-25份、茶树根5-25份、昙花5-25份、荜茇5-20份、刺龙牙5-25份、薄荷5-25份、柏子仁5-25份、葶苈子5-20份、血风藤5-25份、龙眼肉5-25份、乌金草5-20份、马鞭草5-25份、回心草5-25份、绢毛菊5-20份、独叶岩珠5-25份、肿节风5-25份、瓜萎皮5-20份、黑点草5-25份、仙茅5-25份、甘草5-15份。
2.根据权利要求1所述一种治疗病毒性心肌炎的中药组合物，其特征在于：其中药原料及重量份配比为：黄芪20份、水红花子15份、罗布麻10份、麦冬15份、石龙刍15份、茶树根15份、昙花15份、荜茇10份、刺龙牙15份、薄荷15份、柏子仁15份、葶苈子10份、血风藤15份、龙眼肉15份、乌金草10份、马鞭草15份、回心草15份、绢毛菊10份、独叶岩珠15份、肿节风15份、瓜萎皮10份、黑点草15份、仙茅15份、甘草10份。
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CN103520474A (zh) * 2013-10-14 2014-01-22 刘文武 一种治疗病毒性心肌炎的中药制剂
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CN103520474A (zh) * 2013-10-14 2014-01-22 刘文武 一种治疗病毒性心肌炎的中药制剂
CN105079438A (zh) * 2015-09-11 2015-11-25 山东大学 一种治疗病毒性心肌炎的药物制剂

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