CN105943597A - Traditional Chinese medicine composition capable of enhancing immunity and preventing and treating radiation diseases - Google Patents
Traditional Chinese medicine composition capable of enhancing immunity and preventing and treating radiation diseases Download PDFInfo
- Publication number
- CN105943597A CN105943597A CN201610487403.2A CN201610487403A CN105943597A CN 105943597 A CN105943597 A CN 105943597A CN 201610487403 A CN201610487403 A CN 201610487403A CN 105943597 A CN105943597 A CN 105943597A
- Authority
- CN
- China
- Prior art keywords
- parts
- chinese medicine
- medicine composition
- radix
- traditional chinese
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/41—Crassulaceae (Stonecrop family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/487—Psoralea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a traditional Chinese medicine composition capable of enhancing immunity and preventing and treating radiation diseases. Through the adoption of the traditional Chinese medicine composition, the problem of low immunity caused by long-term received radiation can be effectively solved, and the radiation hazard is reduced. The traditional Chinese medicine composition provided by the invention is made from the following components in parts by weight: 25-30 parts of rhodiola rosea, 12-15 parts of radix angelica sinensis,10-14 parts of gingko leaves, 8-12 parts of radix astragali, 6-8 parts of malaytea scurfpea fruits, 6-8 parts of rhizoma ligustici wallichii and 3-6 parts of pseudo-ginseng. The preparation method of the traditional Chinese medicine composition comprises the following steps: cutting up the medical raw materials, mixing the cut-up medical raw materials together, performing decoction with 60-75% ethanol, filtering decoction liquid, and performing vacuum concentration so as to obtain viscous pasty fluid namely the traditional Chinese medicine composition.
Description
Technical field
The present invention relates to compositions, a kind of Chinese medicine composition improving immunity and preventing and treating radiation.
Background technology
Along with the high speed development of modern science and technology, radiation becomes the harm generally existed in people's life, and such as hands is mechanical, electrical
Brain, electromagnetic oven etc. can produce the electromagnetic radiation source of various forms, different frequency, varying strength.Long-term raying is irradiated, meeting
Make human body produce discomfort, serious caused human organ and the damage of system, cause the generation of various disease, such as: leukemia,
Aplastic anemia, various tumor, retinopathy, reproductive system disease, senilism etc.；Tradition Anti-Radiation Countermeasures is mainly at electricity
Install radiation prevention film on device additional, or wear anti-radiation clothes etc..These methods are all to realize radioprotective by physical method, it is impossible to make people
Body forms self radiation protective mechanism.Patent CN201510455861.3 discloses a kind of alimentation composition reducing radiation hazradial bundle,
Having certain radiation resistance, patent CN 201410022608.4 discloses a kind of with Radix Pseudostellariae, Fructus Psoraleae, Fructus Lycii, stone
The compositions that dry measure used in former times etc. are component has good radiation resistance.
Summary of the invention
For above-mentioned situation, the present invention provides a kind of Chinese medicine composition improving immunity and preventing and treating radiation, by difference
The synergism of Chinese medicine, improves immunity, for alleviating or reduce the long-term harm accepting radiation.
The present invention adopts the following technical scheme that, this Chinese medicine composition, makes with following component for raw material: Radix Rhodiolae, Radix Angelicae Sinensis,
Folium Ginkgo, the Radix Astragali, Fructus Psoraleae, Rhizoma Chuanxiong, Radix Notoginseng, by above-mentioned raw medicinal material raw material chopping, mix, use ethanol water
Decocting, decoction liquor filters, and concentrating under reduced pressure obtains the mastic of thickness, obtains described Chinese medicine composition.
Further, preferably, the Chinese medicine composition that the present invention provides, make with following component for raw material: red
Herba hylotelephii erythrosticti 25-30 part, Radix Angelicae Sinensis 12-15 part, Folium Ginkgo 10-14 part, Radix Astragali 8-12 part, Fructus Psoraleae 6-8 part, Rhizoma Chuanxiong 6-8 part, Radix Notoginseng 3-
6 parts.By above-mentioned medicinal raw material chopping, mixing, decoct with the ethanol of 60-75%, decoction liquor filters, concentrating under reduced pressure,
To the mastic of thickness, obtain described Chinese medicine composition.
Preferably, Radix Rhodiolae 25-28 part, Radix Angelicae Sinensis 12-13 part, Folium Ginkgo 10-14 part, Radix Astragali 8-10 part, Fructus Psoraleae 6-8
Part, Rhizoma Chuanxiong 6-8 part, Radix Notoginseng 3-6 part are as raw material.It is highly preferred that Radix Rhodiolae 26 parts, Radix Angelicae Sinensis 12 parts, Folium Ginkgo 13 parts, the Radix Astragali 9
Part, Fructus Psoraleae 7 parts, Rhizoma Chuanxiong 7 parts, Radix Notoginseng 4 parts.
Further, ethanol water volumetric usage is 5-11 times of raw medicinal material weight, preferred alcohol aqueous solution volume
Consumption is 7-9 times of raw medicinal material weight.
Detailed description of the invention
For the object, technical solutions and advantages of the present invention are better described, below in conjunction with specific embodiment to the present invention
It is described further.
Embodiment 1
Radix Rhodiolae 26 parts, Radix Angelicae Sinensis 12 parts, Folium Ginkgo 13 parts, the Radix Astragali 9 parts, Fructus Psoraleae 7 parts, Rhizoma Chuanxiong 7 parts, Radix Notoginseng 4 parts；By above-mentioned
Raw medicinal material shreds, and mixes, and the ethanol with 60% decocts, and decoction liquor filters, and concentrating under reduced pressure obtains the mastic of thickness, its
In ethanol volumetric usage is medicinal raw material weight 7 times of 60%.
Embodiment 2
Radix Rhodiolae 27 parts, Radix Angelicae Sinensis 13 parts, Folium Ginkgo 10 parts, the Radix Astragali 10 parts, Fructus Psoraleae 8 parts, Rhizoma Chuanxiong 6 parts, Radix Notoginseng 3 parts；By above-mentioned
Raw medicinal material chopping, mix, with 65% ethanol decoct, decoction liquor filtration, concentrating under reduced pressure, obtain the mastic of thickness,
Wherein ethanol volumetric usage is medicinal raw material weight 9 times of 65%.
Embodiment 3
Radix Rhodiolae 30 parts, Radix Angelicae Sinensis 15, Folium Ginkgo 14 parts, the Radix Astragali 8 parts, Fructus Psoraleae 12 parts, Rhizoma Chuanxiong 7 parts, Radix Notoginseng 6 parts.By above-mentioned
Medicinal raw material shreds, and mixes, and the ethanol with 75% decocts, and decoction liquor filters, and concentrating under reduced pressure obtains the mastic of thickness, its
In ethanol volumetric usage is medicinal raw material weight 8 times of 75%.
1. Antiradiation injury experiment:
With mice as object of study, investigate the Chinese medicine composition of the embodiment of the present invention 1 to 30 days survival rates of raying mice
Affecting, the human body of the Chinese medicine composition of the present invention recommends consumption to be 6g/60kg.BW every day, and following basic, normal, high dosage group is suitable
In 1 times, 5 times, 10 times of human body recommended dose, and test as follows:
(1) selecting SD mice, female 60, weight range is 19-22g.Raise one week in the case of feeding environment is identical；
(2) being randomly divided into 5 groups, often group 12, is divided into normal group, model control group, low dose group, middle dosage group, high dose group；
Normal group refuses any process, and model group gives distilled water, and basic, normal, high dosage component does not give the embodiment 1 of corresponding dosage
Chinese medicine composition, uses the mode of gavage (ig), every day 1 time, continuous gavage 30d；
5h after (3) the 30th days gavages, in addition to normal group, remaining 4 groups all carry out whole body disposable 60Co gamma-rays irradiate, irradiate away from
From for 1.0m, exposure dose is 8.5Gy；After irradiation, observed and recorded respectively organizes the survival state of mice, body weight change, calculates each group little
The mean survival time of Mus, 30d survival rate etc..
The Chinese medicine composition of the present invention is as shown in table 1 to the result (x ± s) of 30 days survival rates of raying mice.
Table 1
Survived as it can be seen from table 1 the Chinese medicine composition of the present invention can significantly improve by 8.5Gy roentgenization mice 30d
Rate, extends the life span of raying mice, and therefore, the Chinese medicine composition of the present invention has certain preventing and treating radiation effects.
2, the impact on spleen
Spleen is maximum lymphatic organ, is also one of important peripheral immune organ, containing substantial amounts of T cell, NKT
Cell and Tumor-infiltrating lymphocytes etc..Spleen is also the place that haematogenous antigen produces immunne response, can synthesize
And secrete such as the bioactive substance such as complement, IFN, spleen weight reflects the immune state of body indirectly.Research display, irradiates comparison
Group mice spleen heavily significantly reduces, and gives the present invention Chinese medicine composition of high, medium and low dosage, significantly increases mice after irradiation
Spleen weight, the present invention is high, middle, and dosage group compares with irradiation control group, has significant difference.Result is as shown in table 2:
The impact on spleen of table 2 Chinese medicine composition of the present invention
Above experimental result shows indirectly, and the Chinese medicine composition of the present invention can improve body immunity, thus prevents and treats radiation, fall
Low emissivity endangers.
The foregoing is only the optimal case study on implementation of the present invention, be merely illustrative for the purpose of the present invention, and unrestricted
Property.Those skilled in the art understands, it can be carried out some and revise in the scope of the claims in the present invention, but all
To fall within the scope of protection of the present invention.
Claims (6)
1. the Chinese medicine composition improving immunity and preventing and treating radiation, it is characterised in that described Chinese medicine composition uses such as lower section
Prepared by method: with Radix Rhodiolae, Radix Angelicae Sinensis, Folium Ginkgo, the Radix Astragali, Fructus Psoraleae, Rhizoma Chuanxiong, Radix Notoginseng as raw material, and raw material shreds, and mixes,
Decocting with ethanol water, decoction liquor filters, and concentrating under reduced pressure obtains the mastic of thickness, obtains described Chinese medicine composition.
Chinese medicine composition the most according to claim 1, it is characterised in that the consumption of each raw material is: Radix Rhodiolae 25-30 part, when
Return 12-15 part, Folium Ginkgo 10-14 part, Radix Astragali 8-12 part, Fructus Psoraleae 6-8 part, Rhizoma Chuanxiong 6-8 part, Radix Notoginseng 3-6 part.
3. according to the Chinese medicine composition described in claim 1-2, it is characterised in that the consumption of each raw material is: Radix Rhodiolae 25-28 part,
Radix Angelicae Sinensis 12-13 part, Folium Ginkgo 10-14 part, Radix Astragali 8-10 part, Fructus Psoraleae 6-8 part, Rhizoma Chuanxiong 6-8 part, Radix Notoginseng 3-6 part.
4. according to the Chinese medicine composition described in claim 1-3, it is characterised in that the consumption of each raw material is: Radix Rhodiolae 26 parts, when
Return 12 parts, Folium Ginkgo 13 parts, the Radix Astragali 9 parts, Fructus Psoraleae 7 parts, Rhizoma Chuanxiong 7 parts, Radix Notoginseng 4 parts.
5. according to the Chinese medicine composition described in claim 1-4, it is characterised in that described ethanol water is the ethanol of 60-75%,
Ethanol water volumetric usage is 5-11 times of raw medicinal material weight.
6. according to the Chinese medicine composition described in claim 1-5, it is characterised in that ethanol water volumetric usage is raw material weight
7-9 times.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610487403.2A CN105943597A (en) | 2016-06-29 | 2016-06-29 | Traditional Chinese medicine composition capable of enhancing immunity and preventing and treating radiation diseases |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610487403.2A CN105943597A (en) | 2016-06-29 | 2016-06-29 | Traditional Chinese medicine composition capable of enhancing immunity and preventing and treating radiation diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105943597A true CN105943597A (en) | 2016-09-21 |
Family
ID=56901604
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610487403.2A Pending CN105943597A (en) | 2016-06-29 | 2016-06-29 | Traditional Chinese medicine composition capable of enhancing immunity and preventing and treating radiation diseases |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105943597A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101391025A (en) * | 2007-09-22 | 2009-03-25 | 杨光孝 | Anti-radiation preparation and production technique thereof |
| CN102380016A (en) * | 2011-11-22 | 2012-03-21 | 中国人民解放军第三军医大学第二附属医院 | Anti-radiation traditional Chinese medicine composition |
| CN102389511A (en) * | 2011-11-22 | 2012-03-28 | 中国人民解放军第三军医大学第二附属医院 | Anti-radiation Chinese medicine preparation and preparation method thereof |
-
2016
- 2016-06-29 CN CN201610487403.2A patent/CN105943597A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101391025A (en) * | 2007-09-22 | 2009-03-25 | 杨光孝 | Anti-radiation preparation and production technique thereof |
| CN102380016A (en) * | 2011-11-22 | 2012-03-21 | 中国人民解放军第三军医大学第二附属医院 | Anti-radiation traditional Chinese medicine composition |
| CN102389511A (en) * | 2011-11-22 | 2012-03-28 | 中国人民解放军第三军医大学第二附属医院 | Anti-radiation Chinese medicine preparation and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 苗明三主编: "《中药药理学》", 31 March 2013, 湖南科学技术出版社 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102018937B (en) | Medicament for treating acne and preparation method thereof | |
| CN103446567B (en) | Premenstrual ease pharmaceutical composition and preparation technique thereof | |
| CN103751497A (en) | Medicament for treating mastitis and preparation method thereof | |
| CN104758229A (en) | Pure natural acne-removing facial mask | |
| CN103446376A (en) | Traditional Chinese medicine composition used for treating radiation proctitis | |
| CN101632817A (en) | Chinese medicinal composition for treating breast lumps | |
| CN104491689A (en) | Ionization radiation injury protective agent | |
| CN104491688A (en) | Preparation method of biological agent for preventing electromagnetic radiation | |
| CN101366903A (en) | Traditional Chinese medicine composition for treating climacteric syndrome | |
| CN103349763A (en) | Drug for treating acquired immune deficiency syndrome | |
| CN105943597A (en) | Traditional Chinese medicine composition capable of enhancing immunity and preventing and treating radiation diseases | |
| CN101549040A (en) | New application of Chinese Herbal Medicine scutellaria, red peony root and rehmanniae radix for clearing heat, cooling and activating blood and curing acne | |
| CN104306846A (en) | Traditional Chinese medicine for treating attention deficit hyperactivity disorder | |
| CN102961647A (en) | Traditional Chinese medicine for treating osteoporosis | |
| CN105902970A (en) | Chuanxiong rhizome-containing traditional Chinese medicine composition for preventing and treating radiation | |
| CN103908614B (en) | A kind of medicine of live pig preventive care | |
| CN105213972A (en) | A kind of pharmaceutical preparation of promoting blood circulation to remove obstruction in the collateral and application thereof | |
| CN105213973A (en) | For alleviating the pharmaceutical composition of symptom before feminine menstrual | |
| CN104043085A (en) | Traditional Chinese medicine for treating vomitus gravidarum | |
| CN104127602A (en) | Traditional Chinese medicine for treating fatty liver | |
| CN105902607A (en) | Fiveleaf gynostemma herb-containing traditional Chinese medicine composition | |
| CN108126154A (en) | A kind of preparation method and application for the nano dispersion fluid for treating obstruction of collaterals by blood stasis arthralgia-syndrome pain | |
| CN103341111A (en) | Traditional Chinese medicine composition for treating spermatorrhea | |
| CN103800812A (en) | Traditional Chinese medicine radix curcumae-tangerine peel powder for treating anorexia | |
| CN101569683A (en) | New application of Chinese herbal medicaments of baikal skullcap root, phellodendron, cortex moutan, chrysanthemum, liquorice, red peony root and forsythia fruit for treating acne |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20160921 |
|
| WD01 | Invention patent application deemed withdrawn after publication |