CN105943045A - High-precision bio-electrical impedance measuring system and method for body composition analysis - Google Patents
High-precision bio-electrical impedance measuring system and method for body composition analysis Download PDFInfo
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- CN105943045A CN105943045A CN201610331163.7A CN201610331163A CN105943045A CN 105943045 A CN105943045 A CN 105943045A CN 201610331163 A CN201610331163 A CN 201610331163A CN 105943045 A CN105943045 A CN 105943045A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/053—Measuring electrical impedance or conductance of a portion of the body
- A61B5/0537—Measuring body composition by impedance, e.g. tissue hydration or fat content
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4869—Determining body composition
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7221—Determining signal validity, reliability or quality
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Abstract
The invention relates to a high-precision bio-electrical impedance measuring system and measuring method for body composition analysis. The system comprises an upper computer, an electrode assembly, a micro controller, a signal generating module, a signal conditioning module and a signal processing module, wherein the micro controller is connected to the upper computer, the signal generating module, the signal conditioning module and the signal processing module; the signal generating module,the signal conditioning module and the signal processing module are sequentially connected; the signal conditioning module and the electrode assembly are connected; the electrode assembly is arranged on the surface of a to-be-detected object; the micro controller is used for transmitting a measuring command and generating an excitation signal; on one aspect, the excitation signal flows to a sampling circuit, so that an excitation current sample signal is obtained, and on the other aspect, the excitation signal is transmitted to the to-be-detected object by virtue of the signal conditioning module and a response voltage signal is returned; and the response voltage signal and the excitation signal flow to the micro controller by virtue of the signal processing module and are processed by the upper computer. Compared with the prior art, the measuring system and the measuring method disclosed by the invention have the advantages of being high in safety, good in high-frequency performance, high in data acquisition speed, high in accuracy and the like.
Description
Technical field
The present invention relates to Electrical Bioimpedance Measurement Technology field, particularly relate to a kind of height for bioelectrical impedance analysis
Precision bio-impedance measurement system.
Background technology
Along with progress and the development of human lives, people are more and more higher for the requirement of medical treatment, and not requiring nothing more than can be faster
Preferably cure diseases, more requirement can reduce the misery of self during curing the disease as far as possible.Therefore, this is just to medical treatment
Instrument is had higher requirement, and promotes its development to innovate.Owing to biological tissue's electrical impedance technology can be carried out
Cell measurement, cubing, human tissue structure analysis, bioelectrical impedance analysis etc., have noinvasive, cheap, peace
The features such as entirely, nontoxic, simple to operate and abundant information so that the present invention is in pathology detection and health monitoring side
Mask has operability, especially has the biggest application prospect and social meaning to be worth in bioelectrical impedance analysis field.
Bio-electrical impedance is one of physical quantity of reflection biological tissue, organ, cell and whole organism electrical properties,
It can help to obtain relevant tissue signature, physiology and pathological information, thus reach clinical monitoring, pathology detection and
The purpose of health monitoring.Biological tissue's electrical impedance technology is a kind of electrical characteristics utilizing biological tissue and organ and change thereof
Change the lossless decomposition technology extracting the biomedical information relevant to organization factors, i.e. by being placed in organism surface
Electrode apply the ac-excited signal of telecommunication of a safety, measurement response voltage signal to measurand, detection is corresponding
Electrical impedance and change thereof.
Bioelectrical impedance analysis is from producing till now at measuring method and measurement frequency both direction development.Measuring
Method aspect, initial electric bridge method carries out impedance bioelectrical measurement, and principle is simple but precision is relatively low；After propose bipolar electrode
Method, but due to the impact of contact impedance, impedance measurement error is bigger；Four electrode method is the most mostly used to carry out
Measuring, i.e. two electrodes add exciting current signal, two electrode measurement voltages.In terms of measuring frequency, initially use
Unifrequency (50kHz) electric current encourages；After in order to obtain more rich bio-electrical impedance information, be born many
Frequently system.At present, existing related experiment demonstrates the feasibility of bio-electrical impedance measuring, has correlational study to demonstrate,prove simultaneously
Understand bio-electrical impedance and pathological parameter and the relation of human body component.Research shows, by measuring and analyzing biology
The anti-information of tissue resistance, can obtain body water, muscle, fat, inorganic salt equal size, thus reach human body
The purpose of component analysis.
But, current Electrical Bioimpedance Measurement Technology there is also more deficiency, is mainly manifested in most systems
Using simple signal to encourage, the bio-electrical impedance information obtained is the abundantest, even if use multifrequency measurement is
Uniting, its upper limiting frequency is relatively low, phase measurement is inaccurate.Meanwhile, the many employings of existing bio-impedance measurement system
Four opponents, foot electrode measure, and the information measurement precision of abdominal part and trunk is relatively low.Presently, there are for biology
The related invention of impedance measurement, major part is provided to make to be subject to inspection people more convenient to use, and in certainty of measurement
This improvement on the one hand not enough is less, and these deficiencies limit human body based on bio-electrical impedance to a certain extent
Divide the application of analytical technology, therefore, invent a kind of high precision bio-impedance measurement system based on electrical impedance method tool
There are bigger realistic meaning and practical value.
Summary of the invention
The purpose of the present invention is contemplated to the defect overcoming existing Electrical Bioimpedance Measurement Technology to exist, and therefore designs
A kind of high precision bio-impedance measurement system for bioelectrical impedance analysis.This system is protected by the isolation of safety
Protect, the appropriate design such as the high-speed parallel conditioning of exciting current sample circuit, voltage and current signal and analog digital conversion and
The configuration of eight pairs of electrodes, has reached the purpose of safety, broadband, high-acruracy survey.
The purpose of the present invention can be achieved through the following technical solutions:
A kind of high precision bio-impedance measurement system for bioelectrical impedance analysis, including host computer, electrode assemblie,
Microcontroller, signal generating module, Signal-regulated kinase and signal processing module, described microcontroller connects respectively
Host computer, signal generating module, Signal-regulated kinase and signal processing module, described signal generating module, signal
Conditioning module, signal processing module are sequentially connected with, and described Signal-regulated kinase is connected with electrode assemblie, described signal
Occur module include the Direct Digital Synthesizer being sequentially connected with, program control rheostat, differential signal change-over circuit,
First isolating transformer, driving source, sample circuit and the first filter circuit, described Direct Digital Synthesizer
Being connected with microcontroller, described sample circuit is connected with Signal-regulated kinase, at described first filter circuit and signal
Reason module connects, wherein:
Direct Digital Synthesizer, is used for producing sine-wave current signal, and the frequency of this signal, phase place are by micro-
Controller controls；
Program control rheostat, for being converted into sine by the sine-wave current signal that Direct Digital Synthesizer produces
Wave voltage signal；
Differential signal change-over circuit, is converted into two amplitudes for the sine voltage signal produced by program control rheostat
Identical, the differential signal of phase 180 °；
First isolating transformer, sends excitation to after the differential signal isolation produced by differential signal change-over circuit
Source；
Driving source, for producing pumping signal according to the differential signal after isolation；
Sample circuit, for gather amplitude that driving source produces, the exciting current signal that is applied to measurand with
Phase place, and pumping signal is sent to Signal-regulated kinase；
First filter circuit, is filtered for the signal producing sample circuit, and is passed through by filtered signal
Signal processing module is transferred to microcontroller.
Described microcontroller passes sequentially through the second isolating chip and serial ports and communicates to connect with host computer.
Described Signal-regulated kinase includes relay, buffering follow circuit, analog switch, the second filter circuit and the
Three isolating chips, described relay is connected with signal generating module, and described relay, electrode assemblie, buffering are followed
Circuit, analog switch and the second filter circuit are sequentially connected with, and described analog switch passes through the 3rd isolating chip and micro-control
Device processed connects, wherein:
Relay, for receiving the pumping signal that signal generating module sends, gating treats exciting electrode；
Buffering follow circuit, for receiving the response voltage signal of electrode assemblie, and enters described response voltage signal
Row buffering and isolation；
Analog switch, is used for gating electrode to be measured；
Second filter circuit, for the filtering of described response voltage signal；
3rd isolating chip, isolates for the control signal producing microcontroller, is then sent to simulation and opens
Close conducting and the shutoff controlling analog switch.
The first isolating chip that described signal processing module includes being sequentially connected with, the first adc circuit, data buffer storage
Module, the second adc circuit and the second isolating transformer, described first isolating chip and the first filter circuit connect,
Described second isolating transformer is connected with Signal-regulated kinase, and described data cache module is connected with microcontroller, its
In:
First isolating chip, for isolating through the first filtered signal of filter circuit；
First adc circuit, for being sent to data buffer storage mould to after the signal simulation/numeral conversion after isolation
Block；
Second isolating transformer, for isolating the response voltage signal that Signal-regulated kinase produces and be sent to second
Adc circuit；
Second adc circuit, for being simulated/numeral conversion to the response voltage signal after isolation；
Data cache module, the analog/digital for caching the first adc circuit, the second adc circuit output turns
Change result.
Described data cache module caches described analog/digital conversion result with the form of purely logical control.
Described electrode assemblie includes eight pairs of electrodes, respectively two opponent's electrodes, two pairs of foot electrodes and four pairs of stem electrode,
During application, described four pairs of stem electrode are arranged in the surface of trunk different parts.
A kind of measuring method based on the high precision bio-impedance measurement system for bioelectrical impedance analysis, including with
Lower step:
1) host computer sends measuring command to microcontroller；
2) measuring command is sent to signal generating module by microcontroller, and signal generating module is according to described measuring command
Sending pumping signal, detailed process is:
201) Direct Digital Synthesizer receives measuring command, receives the clock letter that microcontroller provides simultaneously
Number, produce a sine-wave current signal, and deliver to program control rheostat；
202) sine-wave current signal received is converted into sine voltage signal by program control rheostat, and deliver to poor
Sub-signal change-over circuit；
203) the sine voltage signal received is converted into that two amplitudes are identical, phase place by differential signal change-over circuit
Differ the differential signal of 180 °, and deliver to the first isolating transformer；
204) differential signal received is isolated and is sent to driving source by the first isolating transformer；
205) driving source produces pumping signal；
206) sample circuit sends described pumping signal to Signal-regulated kinase, simultaneously to being applied to measurand
Exciting current signal carries out the collection of amplitude and phase place, and by the signal that collects successively through the first filter circuit,
One isolating chip, the first adc circuit, finally cache numeric results to data cache module；
207) numeric results in microcontroller obtains data cache module, obtains exciting current after carrying out digital demodulation
The amplitude of signal and phase information；
3) Signal-regulated kinase receives the pumping signal that signal generating module sends, and described pumping signal is passed through electrode
Assembly acts on measurand, responds electricity according to the measuring command of microcontroller accordingly to signal processing module transmission
Pressure signal；
4) signal processing module described response voltage signal is isolated successively, analog/digital conversion and caching；
5) signal processing module is written and read obtaining analog/digital conversion result by microcontroller, and through digital solution
Adjust amplitude and the phase information obtaining response voltage signal；
6) the exciting current signal after demodulation and amplitude and the phase information responding voltage signal are uploaded by microcontroller
Carry out data process to host computer, obtain bio-electrical impedance information.
Described step 3) in, the concrete generation process of response voltage signal is:
301) treat exciting electrode during relay receives pumping signal backgating electrode assemblie, and send pumping signal
To treating exciting electrode；
302) pumping signal is delivered to measurand and receives the response voltage signal that measurand is passed back by electrode assemblie,
Response voltage signal is sent to buffer follow circuit simultaneously buffer and isolate；
303) measuring command that analog switch produces according to the microcontroller received gates electrode to be measured；
304) the response voltage signal that the measurement electrode being strobed is passed back is filtered by the second filter circuit, and delivers to
Signal processing module.
Described step 4) particularly as follows:
401) the response voltage signal received is isolated and is sent to the second adc circuit by the second isolating transformer；
402) the response voltage signal after the isolation that the second adc circuit will receive is simulated/numeral conversion, will
Transformation result is delivered to data cache module and is cached.
Compared with prior art, the bio-impedance measurement system of the present invention can be simultaneously to exciting current signal and quilt
The response voltage signal surveying object carries out high-speed synchronous analog/digital conversion, it is achieved high-precision bio-electrical impedance
It is obtained in that the phase information of electrical impedance accurately while amplitude measurement, has the advantages that
1) in the present invention, all signals being connected with measurand all have passed through isolating chip, has adequately protected tested
Object, improves the safety of system.
2) data cache module SRAM used in the present invention caches analog/digital with the form of purely logical control
Transformation result, improves acquisition speed.
3) present invention is arranging exciting current sample circuit as exciting current detector unit at exciting electrode,
This exciting current sampled signal and tested response voltage signal carry out high-speed synchronous analog/digital conversion, in order to synchronize
Measure exciting current signal and the amplitude of response voltage signal and phase place, improve amplitude and the phase place of bio-electrical impedance
The accuracy measured, and improve high frequency performance.
4) present invention uses eight electrode to carry out people's body section impedance bioelectrical measurement, i.e. except commonly used in the prior art
Outside hands, foot four are to electrode, add four pairs of stem electrode, promote sensitivity and accuracy that metastomium is measured.
5) four pairs of stem electrode can be positioned over trunk different parts according to different application target, it is simple at any time according to reality
Border situation selects optimum measurement scheme, reaches optimum measurement effect；Four pairs of moveable stem electrode solve the most well
Determine the measurement problem when measurand is inconvenient to carry out the similar actions such as upset.
Accompanying drawing explanation
Fig. 1 is the present invention system block diagram for the high precision bio-impedance measurement system of bioelectrical impedance analysis.
In figure: 1, host computer, 2, microcontroller, 3, signal generating module, 4, Signal-regulated kinase, 5,
Signal processing module, 101, serial ports, the 102, second isolating chip, 103, Direct Digital Synthesizer,
104, program control rheostat, 105, differential signal change-over circuit, the 106, first isolating transformer, 107, driving source,
108, sample circuit, the 109, first filter circuit, the 110, first isolating chip, the 111, first adc circuit,
112, relay, 113, electrode assemblie, 114, buffering follow circuit, 115, analog switch, the 116, second filter
Wave circuit, the 117, second isolating transformer, the 118, second adc circuit, 119, data cache module, 120,
3rd isolating chip.
Detailed description of the invention
The present invention is described in detail with specific embodiment below in conjunction with the accompanying drawings.The present embodiment is with the technology of the present invention side
Implement premised on case, give detailed embodiment and concrete operating process, but the protection model of the present invention
Enclose and be not limited to following embodiment.
As it is shown in figure 1, this enforcement provides a kind of high precision bio-impedance measurement system for bioelectrical impedance analysis
System, including host computer 1, electrode assemblie 113, microcontroller 2, signal generating module 3, Signal-regulated kinase 4
With signal processing module 5, microcontroller 2 connects host computer 1, signal generating module 3, signal condition mould respectively
Block 4 and signal processing module 5, signal generating module 3, Signal-regulated kinase 4, signal processing module 5 are successively
Connecting, Signal-regulated kinase 4 is connected with electrode assemblie 113.
Microcontroller 2 passes sequentially through the second isolating chip 102 and communicates with host computer 1 with serial ports (UART) 101
Connect, be used for preparing signal generating module 3, Signal-regulated kinase 4 and signal processing module 5, produce clock letter
Number and control signal, control the work of each module, the data passed back carried out digital demodulation process, and with upper simultaneously
Machine communicates.Second isolating chip 102 is set between microcontroller 2 and host computer 1, realizes electrical isolation with host computer
With minimizing host computer, the power supply of this measurement system is disturbed with Earth noise, improve and measure system accuracy.
Signal generating module 3 includes the Direct Digital Synthesizer (DDS) 103 being sequentially connected with, program control change
Resistance device 104, differential signal change-over circuit the 105, first isolating transformer 106, driving source 107, sample circuit
108 and first filter circuit 109, Direct Digital Synthesizer 103 is connected with microcontroller 2, sampling electricity
Road 108 is connected with Signal-regulated kinase 4, and the first filter circuit 109 is connected with signal processing module 5, wherein:
Direct Digital Synthesizer 103, is used for producing sine-wave current signal, and the frequency of this signal, phase place are by micro-
Controller 2 controls；Program control rheostat 104, for the sine wave produced by Direct Digital Synthesizer 103
Current signal is converted into voltage signal；Differential signal change-over circuit 105, for produce program control rheostat 104
Voltage signal is converted into that two amplitudes are identical, the differential signal of phase 180 °, makes the instantaneous electricity that human body is subject to
Stream sum is zero and reduces common-mode voltage；First isolating transformer 106, for by differential signal change-over circuit 105
Driving source 107 is sent to after the differential signal isolation produced；Driving source 107, for according to the difference letter after isolation
Number produce pumping signal；Sample circuit 108, for gathering amplitude and the phase of the pumping signal that driving source 107 produces
Position, and pumping signal is sent to Signal-regulated kinase 4；First filter circuit 109, for sample circuit 108
The signal produced is filtered, and through signal processing module 5, filtered signal is transferred to microcontroller 2.
Signal-regulated kinase 4 includes that relay 112, buffering follow circuit 114, analog switch 115, second are filtered
Wave circuit 116 and the 3rd isolating chip 120, relay 112 is connected with signal generating module 3, relay 112,
Electrode assemblie 113, buffering follow circuit 114, analog switch 115 and the second filter circuit 116 are sequentially connected with,
Analog switch 115 is connected with microcontroller 2, wherein by the 3rd isolating chip 120: relay 112, is used for
Receiving the pumping signal that signal generating module 3 sends, gating treats exciting electrode；Buffering follow circuit 114, is used for
Receive the response signal of electrode assemblie 113, and response signal is buffered and isolates；Analog switch 115, uses
In gating electrode to be measured；Second filter circuit 116, for responding the filtering of signal；3rd isolating chip 120,
Control signal for producing microcontroller 2 is isolated, and the signal after isolation is sent to analog switch
115。
Signal processing module 5 includes first isolating chip the 110, first adc circuit 111, the data being sequentially connected with
Cache module (SRAM) the 119, second adc circuit 118 and the second isolating transformer 117, the second isolation becomes
Depressor 117 is connected with Signal-regulated kinase 4, and data cache module 119 is connected with microcontroller 2, wherein: the
One isolating chip 110, for isolating through the first filtered signal of filter circuit 109；Oneth ADC
Circuit 111, for being sent to data cache module 119 to after the signal simulation/numeral conversion after isolation；The
Two isolating transformers 117, isolate for the response signal produced by Signal-regulated kinase 4 and are sent to the 2nd ADC
Circuit 118；Second adc circuit 118, for being simulated/numeral conversion to the response signal after isolation；Number
According to cache module 119, for the simulation/number of fast cache the first adc circuit the 111, second adc circuit 118
Word transformation result, data cache module 119 caches analog/digital conversion result with the form of purely logical control.
In the present embodiment, electrode assemblie 113 is arranged in measurand skin surface, including eight pairs of electrodes, is respectively
Two opponent's electrodes, two pairs of foot electrodes and four pairs of stem electrode, during application, four pairs of stem electrode can be according to different application
Target is positioned over trunk different parts, it is simple to selects optimum measurement scheme according to practical situation at any time, reaches most preferably to survey
Dose-effect fruit, improves trunk and the sensitivity of abdominal part measurement and precision, improves the accuracy of measurement.
According to foregoing description, survey based on the above-mentioned high precision bio-impedance measurement system for bioelectrical impedance analysis
Metering method can comprise the following steps that
1) host computer sends measuring command, is sent to microcontroller through serial ports and the second isolating chip；
2) measuring command is sent to signal generating module by microcontroller, and sends clock signal to Direct Digital
Frequency synthesizer；
3) produce a sine-wave current signal after Direct Digital Synthesizer receives control signal, and send
To program control rheostat；
4) sine-wave current signal received is converted into voltage signal by program control rheostat, and delivers to differential signal
Change-over circuit；
5) single-ended voltage signal received is converted into that two amplitudes are identical, phase place phase by differential signal change-over circuit
Differ from the differential signal of 180 °, and deliver to the first isolating transformer；
6) differential signal received is isolated and is sent to driving source by the first isolating transformer；
7) driving source produces pumping signal according to the differential signal after isolation, and sequentially pass through sample circuit, the
The sample signal of the exciting current after filtering isolation is delivered to an ADC electricity by one filter circuit and the first isolating chip
Road；
8) the exciting current signal after analog/digital conversion is delivered to microcontroller, microcontroller by the first adc circuit
Device obtains amplitude and the phase information of exciting current signal after carrying out digital demodulation；
9) pumping signal that exciting circuit produces is sent to Signal-regulated kinase while flowing to the first filter circuit；
10) relay receives the electrode that pumping signal backgating is to be encouraged, and sends pumping signal to exciting electrode；
11) electrode is arranged in measurand skin surface, and small safe exciting current signal is delivered to measurand
And receive the response voltage signal that measurand is passed back, response voltage signal is returned to buffer follow circuit simultaneously and enters
Row buffering and isolation；
12) measuring command of microcontroller delivers to analog switch after the 3rd isolating chip isolation, wraps in measuring command
Including the control signal for controlling analog switch, analog switch measures electrode according to the control signal gating received；
13) the response voltage signal that the measurement electrode being strobed is passed back is filtered by the second filter circuit, and delivers to
Signal-regulated kinase；
14) the response voltage signal received is isolated and sends back back-end circuit by the second isolating transformer；
15) at the response voltage signal simulation/numeral conversion after the isolation that the second adc circuit will receive
Reason, and deliver to data cache module；
16) microcontroller is written and read obtaining sampled data to data cache module, and obtains sound through digital demodulation
The amplitude of induction signal and phase information；
17) pumping signal after demodulation and amplitude and the phase information responding signal are delivered to by microcontroller by serial ports
Host computer carries out data process, obtains bio-electrical impedance information.
Claims (9)
1. for the high precision bio-impedance measurement system of bioelectrical impedance analysis, including host computer (1),
Electrode assemblie (113), microcontroller (2), signal generating module (3), Signal-regulated kinase (4) and signal
Processing module (5), described microcontroller (2) connects host computer (1), signal generating module (3), letter respectively
Number conditioning module (4) and signal processing module (5), described signal generating module (3), Signal-regulated kinase (4),
Signal processing module (5) is sequentially connected with, and described Signal-regulated kinase (4) is connected with electrode assemblie (113),
It is characterized in that,
Direct Digital Synthesizer (103) that described signal generating module (3) includes being sequentially connected with, program control
Rheostat (104), differential signal change-over circuit (105), the first isolating transformer (106), driving source (107),
Sample circuit (108) and the first filter circuit (109), described Direct Digital Synthesizer (103) is with micro-
Controller (2) connects, and described sample circuit (108) is connected with Signal-regulated kinase (4), described first filter
Wave circuit (109) is connected, wherein with signal processing module (5):
Direct Digital Synthesizer (103), is used for producing sine-wave current signal, the frequency of this signal, phase
Position is controlled by microcontroller (2)；
Program control rheostat (104), for the sine-wave current produced by Direct Digital Synthesizer (103)
Signal is converted into sine voltage signal；
Differential signal change-over circuit (105), for the sine voltage signal produced by program control rheostat (104)
It is converted into that two amplitudes are identical, the differential signal of phase 180 °；
First isolating transformer (106), for differential signal that differential signal change-over circuit (105) is produced every
Driving source (107) is sent to after from；
Driving source (107), for producing pumping signal according to the differential signal after isolation；
Sample circuit (108), is used for gathering excitation that driving source (107) produces, that be applied to measurand electricity
The amplitude of stream signal and phase place, and pumping signal is sent to Signal-regulated kinase (4)；
First filter circuit (109), is filtered for the signal producing sample circuit (108), and will filter
Signal after ripple is transferred to microcontroller (2) by signal processing module (5).
High precision bio-impedance measurement system for bioelectrical impedance analysis the most according to claim 1,
It is characterized in that, described microcontroller (2) pass sequentially through the second isolating chip (102) and serial ports (101) with
Host computer (1) communicates to connect.
High precision bio-impedance measurement system for bioelectrical impedance analysis the most according to claim 1,
It is characterized in that, described Signal-regulated kinase (4) include relay (112), buffering follow circuit (114),
Analog switch (115), the second filter circuit (116) and the 3rd isolating chip (120), described relay (112)
It is connected with signal generating module (3), described relay (112), electrode assemblie (113), buffering follow circuit
(114), analog switch (115) and the second filter circuit (116) be sequentially connected with, described analog switch (115)
It is connected with microcontroller (2), wherein by the 3rd isolating chip (120):
Relay (112), is used for receiving the pumping signal that signal generating module (3) sends, and gates and treats excitation electricity
Pole；
Buffering follow circuit (114), is used for receiving the response voltage signal of electrode assemblie (113), and to described
Response voltage signal buffers and isolates；
Analog switch (115), is used for gating electrode to be measured；
Second filter circuit (116), for the filtering of described response voltage signal；
3rd isolating chip (120), isolates, then for the control signal producing microcontroller (2)
It is sent to analog switch (115) and controls conducting and the shutoff of analog switch.
High precision bio-impedance measurement system for bioelectrical impedance analysis the most according to claim 3,
It is characterized in that, the first isolating chip (110) that described signal processing module (5) includes being sequentially connected with, first
Adc circuit (111), data cache module (119), the second adc circuit (118) and the second isolation transformation
Device (117), described first isolating chip (110) is connected with the first filter circuit (109), described second isolation
Transformator (117) is connected with Signal-regulated kinase (4), described data cache module (119) and microcontroller
(2) connect, wherein:
First isolating chip (110), for isolating through the first filter circuit (109) filtered signal；
First adc circuit (111), for being sent to data to after the signal simulation/numeral conversion after isolation
Cache module (119)；
Second isolating transformer (117), for the response voltage signal isolation produced by Signal-regulated kinase (4)
And it is sent to the second adc circuit (118)；
Second adc circuit (118), for being simulated/numeral conversion to the response voltage signal after isolation；
Data cache module (119), for caching the first adc circuit (111), the second adc circuit (118)
The analog/digital conversion result of output.
High precision bio-impedance measurement system for bioelectrical impedance analysis the most according to claim 4,
It is characterized in that, described data cache module (119) caches described analog/digital with the form of purely logical control and turns
Change result.
High precision bio-impedance measurement system for bioelectrical impedance analysis the most according to claim 1,
It is characterized in that, described electrode assemblie (113) includes eight pairs of electrodes, respectively two opponent's electrodes, two pairs of foot electricity
Pole and four pairs of stem electrode, during application, described four pairs of stem electrode are arranged in the surface of trunk different parts.
7. one kind based on the high precision bio-impedance measurement system for bioelectrical impedance analysis described in claim 4
The measuring method of system, it is characterised in that comprise the following steps:
1) host computer (1) sends measuring command to microcontroller (2)；
2) measuring command is sent to signal generating module (3), signal generating module (3) root by microcontroller (2)
Sending pumping signal according to described measuring command, detailed process is:
201) Direct Digital Synthesizer (103) receives measuring command, receives microcontroller (2) simultaneously
The clock signal be given, produces a sine-wave current signal, and delivers to program control rheostat (104)；
202) sine-wave current signal received is converted into sine voltage signal by program control rheostat (104),
And deliver to differential signal change-over circuit (105)；
203) the sine voltage signal received is converted into two amplitude phases by differential signal change-over circuit (105)
Same, the differential signal of phase 180 °, and deliver to the first isolating transformer (106)；
204) differential signal received is isolated and is sent to driving source (107) by the first isolating transformer (106)；
205) driving source (107) produces pumping signal；
206) described pumping signal is sent to Signal-regulated kinase (4) by sample circuit (108), simultaneously to applying
Exciting current signal to measurand carries out the collection of amplitude and phase place, and by the signal that collects successively through first
Filter circuit (109), the first isolating chip (110), the first adc circuit (111), finally by numeric results
Cache to data cache module (119)；
207) numeric results in microcontroller (2) obtains data cache module (119), after carrying out digital demodulation
Obtain amplitude and the phase information of exciting current signal；
3) Signal-regulated kinase (4) receives the pumping signal that signal generating module (3) sends, by described excitation letter
Number act on measurand by electrode assemblie (113), according to the measuring command of microcontroller (2) at signal
Reason module (5) sends and responds voltage signal accordingly；
4) described response voltage signal is isolated by signal processing module (5) successively, analog/digital conversion is eased up
Deposit；
5) microcontroller (2) is written and read obtaining analog/digital conversion result to signal processing module (5), and
Amplitude and the phase information of response voltage signal is obtained through digital demodulation；
6) microcontroller (2) is by the exciting current signal after demodulation and the amplitude and the phase information that respond voltage signal
It is uploaded to host computer (1) and carries out data process, obtain bio-electrical impedance information.
Measuring method the most according to claim 7, it is characterised in that described step 3) in, respond voltage signal
Concrete generation process be:
301) exciting electrode is treated during relay (112) receives pumping signal backgating electrode assemblie (113),
And send pumping signal to treating exciting electrode；
302) pumping signal is delivered to measurand and receives the response electricity that measurand is passed back by electrode assemblie (113)
Pressure signal, is sent to response voltage signal buffer follow circuit (114) simultaneously and buffers and isolate；
303) the measuring command gating that analog switch (115) produces according to the microcontroller (2) received is to be measured
Electrode；
304) the response voltage signal that the measurement electrode being strobed is passed back is filtered by the second filter circuit (116),
And deliver to signal processing module (5).
9. according to claim 7 measuring method, it is characterised in that described step 4) particularly as follows:
401) the response voltage signal received is isolated and is sent to the 2nd ADC by the second isolating transformer (117)
Circuit (118)；
402) the response voltage signal after the isolation that the second adc circuit (118) will receive is simulated/numeral
Conversion, delivers to transformation result data cache module (119) and caches.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107463826A (en) * | 2017-08-16 | 2017-12-12 | 联想(北京)有限公司 | A kind of data processing method and electronic equipment |
| CN108577838A (en) * | 2018-05-17 | 2018-09-28 | 杭州永川科技有限公司 | Multichannel electrical impedance tomography circuit and system |
| CN108685572A (en) * | 2018-05-17 | 2018-10-23 | 杭州永川科技有限公司 | Multichannel electrical impedance tomography circuit and system |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1489447A (en) * | 2000-11-29 | 2004-04-14 | ��ʽ���簢�й���9 | Method and device for measuring body composition |
| US20070038140A1 (en) * | 2005-07-07 | 2007-02-15 | Tanita Corporation | Truncal visceral/subcutaneous fat measuring method and apparatus |
| US20090247896A1 (en) * | 2005-10-12 | 2009-10-01 | Omron Healthcare Co., Ltd. | Body fat measuring device capable of accurately measuring visceral fat amount |
| CN101721208A (en) * | 2008-10-31 | 2010-06-09 | 启德电子股份有限公司 | Device and method for measuring biological impedance of multi-limb segment components of human body |
| CN103230272A (en) * | 2013-04-23 | 2013-08-07 | 中国科学院电工研究所 | Method and device for hepatopathy nutrition state detection |
| CN105496409A (en) * | 2016-01-19 | 2016-04-20 | 北京四海华辰科技有限公司 | Human body composition analyzer |
-
2016
- 2016-05-18 CN CN201610331163.7A patent/CN105943045A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1489447A (en) * | 2000-11-29 | 2004-04-14 | ��ʽ���簢�й���9 | Method and device for measuring body composition |
| US20070038140A1 (en) * | 2005-07-07 | 2007-02-15 | Tanita Corporation | Truncal visceral/subcutaneous fat measuring method and apparatus |
| US20090247896A1 (en) * | 2005-10-12 | 2009-10-01 | Omron Healthcare Co., Ltd. | Body fat measuring device capable of accurately measuring visceral fat amount |
| CN101721208A (en) * | 2008-10-31 | 2010-06-09 | 启德电子股份有限公司 | Device and method for measuring biological impedance of multi-limb segment components of human body |
| CN103230272A (en) * | 2013-04-23 | 2013-08-07 | 中国科学院电工研究所 | Method and device for hepatopathy nutrition state detection |
| CN105496409A (en) * | 2016-01-19 | 2016-04-20 | 北京四海华辰科技有限公司 | Human body composition analyzer |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109247937A (en) * | 2017-07-13 | 2019-01-22 | 三星电子株式会社 | The operating method of biological processor, bio signal detection system and biological processor |
| CN109247937B (en) * | 2017-07-13 | 2023-11-24 | 三星电子株式会社 | Biological processor, biological signal detection system, and method of operating biological processor |
| CN107463826A (en) * | 2017-08-16 | 2017-12-12 | 联想(北京)有限公司 | A kind of data processing method and electronic equipment |
| CN109567805A (en) * | 2017-09-29 | 2019-04-05 | 上海交通大学 | High-performance pulmonary function detection system and method based on thorax impedance measurement |
| CN108577838A (en) * | 2018-05-17 | 2018-09-28 | 杭州永川科技有限公司 | Multichannel electrical impedance tomography circuit and system |
| CN108685572A (en) * | 2018-05-17 | 2018-10-23 | 杭州永川科技有限公司 | Multichannel electrical impedance tomography circuit and system |
| CN113453616A (en) * | 2018-12-18 | 2021-09-28 | 皇家飞利浦有限公司 | Inductive sensing system and method |
| WO2021147902A1 (en) * | 2020-01-20 | 2021-07-29 | 北京津发科技股份有限公司 | Multi-channel based skin resistance measuring device and method |
| CN113080923A (en) * | 2021-03-23 | 2021-07-09 | 桂林电子科技大学 | Equivalent bioelectrical impedance measuring method based on bridge method |
| CN113080923B (en) * | 2021-03-23 | 2024-04-02 | 桂林电子科技大学 | Equivalent bioelectrical impedance measuring method based on bridge method |
| CN113827247A (en) * | 2021-09-27 | 2021-12-24 | 中国科学院深圳先进技术研究院 | Spread spectrum modulation electrode contact impedance online measurement device and method |
| WO2024011931A1 (en) * | 2022-07-12 | 2024-01-18 | 深圳迈微医疗科技有限公司 | Tissue ablation apparatus, and electrochemical impedance measurement apparatus and method |
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