CN108577838A - Multichannel electrical impedance tomography circuit and system - Google Patents

Multichannel electrical impedance tomography circuit and system Download PDF

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Publication number
CN108577838A
CN108577838A CN201810476960.3A CN201810476960A CN108577838A CN 108577838 A CN108577838 A CN 108577838A CN 201810476960 A CN201810476960 A CN 201810476960A CN 108577838 A CN108577838 A CN 108577838A
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China
Prior art keywords
signal
module
excitation
processing unit
central processing
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CN201810476960.3A
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Chinese (zh)
Inventor
石崇源
吴冠
宣和均
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Hangzhou Yongchuan Technology Co Ltd
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Hangzhou Yongchuan Technology Co Ltd
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Priority to CN201810476960.3A priority Critical patent/CN108577838A/en
Publication of CN108577838A publication Critical patent/CN108577838A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/053Measuring electrical impedance or conductance of a portion of the body
    • A61B5/0531Measuring skin impedance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/053Measuring electrical impedance or conductance of a portion of the body
    • A61B5/0536Impedance imaging, e.g. by tomography
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7225Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation

Abstract

The present invention provides multichannel electrical impedance tomography circuit and systems, are related to the field of medical instrument technology, wherein the multichannel electrical impedance tomography circuit includes:Central processing unit, current excitation module, encourage assurance module, measurement module and back end processing module, in use, current excitation module is after receiving the detectable signal that central processing unit is sent out, any two test electrode into measurement module sends out current signal, excitation assurance module is used for current signal being adjusted to steady state value, exciting current signal is generated according to steady state value, in this way, remaining test electrode generates multichannel driving voltage signal under exciting current signal function, until all test electrodes all receive exciting current signal, the driving voltage signal that each back end processing module generates the test electrode being attached thereto generates conversion results signal after being amplified and converting, to send central processing unit imaging to, improve the efficiency and precision of imaging.

Description

Multichannel electrical impedance tomography circuit and system
Technical field
The present invention relates to the field of medical instrument technology more particularly to multichannel electrical impedance tomography circuit and systems.
Background technology
Bioelectrical impedance tomography technology is a kind of novel medicine functional imaging technology, its principle is in human body surface Detection electrode is laid, and applies a faint electric current on the electrode and measures the voltage value on other electrodes later, according to Relationship between voltage and electric current reconstructs inside of human body impedance value or the changing value of electrical impedance.Due in this method reality Nucleic or ray are not used during applying, it is therefore, harmless, reuse can be repeatedly measured, its cost is relatively low in addition, Special working environment is not required, and therefore, bioelectrical impedance tomography technology is that one kind is ideal, has broad prospect of application Medical imaging technology.
But in traditional bioelectrical impedance tomography device, usually only four input/output switching compositions, i.e., There are two outputs to switch for emitting portion;There are two input switches for detection part.Due in bioelectrical impedance tomography device Number of poles is more, the switch that the signal in above-mentioned multiple electrodes can not simultaneously Jing Guo emitting portion and detection part, therefore, on The method of stating can only monitor slow change procedure in real time, although imaging still has functionality, limit its application Range.By taking the bioelectrical impedance tomography device with 16 test electrodes as an example, when having 2 electrodes as pumping signal When, adjacent voltage is required for obtaining two-by-two for other electrode (such as 14), then changes excitation electrode pair, all After electrode is to (symmetrical or adjacent) cycle one time, hundreds of data are measured, according to this hundreds of data, are finally inversed by electrode institute really The electrical impedance distribution of fixed plane.There is usually one amplifiers in existing device, therefore, it is difficult to meet high speed measure and The requirement of measurement accuracy.
To sum up, problem relatively low about traditional slow precision of bioelectrical impedance tomography device to test at present, there is no Effective solution method.
Invention content
In view of this, the embodiment of the present invention has been designed to provide multichannel electrical impedance tomography circuit and system, By the way that central processing unit, current excitation module, excitation assurance module, measurement module and back end processing module is arranged, especially with The back end processing module of each test electrode independent connection, improves the speed of signal transmission, and then ensured the efficiency of imaging And precision.
In a first aspect, an embodiment of the present invention provides multichannel electrical impedance tomography circuits, including:Central processing unit, Current excitation module, excitation assurance module, measurement module and back end processing module, wherein the number of the back end processing module It is multiple;
The central processing unit, the excitation assurance module, the current excitation module, the measurement module and each institute Back end processing module is stated to be sequentially connected, and, each back end processing module is connected with the central processing unit, wherein institute It includes multiple test electrodes to state measurement module, and multiple test electrodes are evenly spaced in a plane, and, each survey Examination electrode is connected with a back end processing module;
The current excitation module, for after receiving the detectable signal that the central processing unit is sent out, to the survey Test electrode described in amount mould any two in the block sends out current signal, until all test electrodes all receive it is described Until current signal;
The excitation assurance module generates according to the steady state value and swashs for the current signal to be adjusted to steady state value Encourage current signal;
Remaining described test electrode, for generating multichannel driving voltage signal under the action of the exciting current signal;
Each back end processing module, the driving voltage for being generated to the test electrode being attached thereto are believed Conversion results signal is generated after number being amplified and convert, and is imaged with sending the central processing unit to.
With reference to first aspect, an embodiment of the present invention provides the first possible embodiments of first aspect, wherein every Include that detect and select switch, preamplifier, bandpass filter, the logarithm being sequentially connected are put in a back end processing module Big device and A/D digital quantizers;
It is described to detect and select switch, for being connected to the preamplifier being connected with the test electrode;
The preamplifier obtains the first amplification voltage letter for carrying out Linear Amplifer to the driving voltage signal Number;
The bandpass filter obtains band logical voltage signal for being filtered to the first amplification voltage signal;
The logafier obtains the second amplification voltage letter for carrying out logarithmic amplification to the band logical voltage signal Number;
The A/D digital quantizers obtain digital voltage for carrying out analog-to-digital conversion to the second amplification voltage signal Signal.
The possible embodiment of with reference to first aspect the first, an embodiment of the present invention provides second of first aspect Possible embodiment, wherein multiple switches that detect and select are connected with the central processing unit;
Switch is detected and selected described in multiple, is used to be connected to remaining after the return path signal for receiving the central processing unit Connection between the test electrode and the preamplifier.
The possible embodiment of with reference to first aspect the first, an embodiment of the present invention provides the third of first aspect Possible embodiment, wherein further include the first calibrating resistance in each back end processing module;
One end of first calibrating resistance and the first calibrating resistance phase in the adjacent back end processing module Even, it is circularized until first calibrating resistance in all back end processing modules is sequentially connected, the first calibration electricity The other end of resistance is connected with the switch that detects and selects;
First calibrating resistance, for sending out the first calibration letter to the switch that detects and selects in the central processing unit Number excitation under generate first voltage;
The central processing unit, for the difference between the first voltage measured and the first normal voltage to be denoted as One measured error signal.
The third possible embodiment with reference to first aspect, an embodiment of the present invention provides the 4th kind of first aspect Possible embodiment, wherein further include the second calibrating resistance in each back end processing module, wherein second school Quasi- resistance is different from the resistance value of the first calibrating resistance;
One end of second calibrating resistance and the second calibrating resistance phase in the adjacent back end processing module Even, it is circularized until second calibrating resistance in all back end processing modules is sequentially connected, the second calibration electricity The other end of resistance is connected with the switch that detects and selects;
Second calibrating resistance, for sending out the second calibration letter to the switch that detects and selects in the central processing unit Number excitation under generate second voltage;
The central processing unit, for the difference between the second voltage measured and the second normal voltage to be denoted as Two measured error signals.
With reference to first aspect, an embodiment of the present invention provides the 5th kind of possible embodiments of first aspect, wherein institute Current excitation module is stated to include the current source generator being sequentially connected, exciting amplifier and encourage selecting switch, and, the excitation Selecting switch is connected with the central processing unit;
The current source generator, for generating excitation electricity after receiving the detectable signal that the central processing unit is sent out Stream;
The exciting amplifier obtains the exciting current signal for being amplified to the exciting current;
The excitation selecting switch tests electrode for being connected under the control of the central processing unit described in any two With the connection between the exciting amplifier.
The 5th kind of possible embodiment with reference to first aspect, an embodiment of the present invention provides the 6th kind of first aspect Possible embodiment, wherein the number of the excitation selecting switch is two, and, two excitation selecting switch series connection, One of them described excitation selecting switch ground connection;
The unearthed excitation selecting switch, for sending out exciting current signal to test electrode described in any two During, level-one isolation is carried out to remaining described described test electrode;
The excitation selecting switch of ground connection, for sending out exciting current signal to test electrode described in any two In the process, two level isolation is carried out to remaining described described test electrode.
With reference to first aspect, an embodiment of the present invention provides the 7th kind of possible embodiments of first aspect, wherein institute It includes feedback detection resistance, feedback amplifier and feedback A/Ds to state excitation assurance module;
The exciting amplifier and the excitation selecting switch are connected with the input terminal of the feedback amplifier, described anti- Feedback detection resistance is connected in parallel on the input terminal of the feedback amplifier, the feedback amplifier and the feedback A/Ds phase Even, the feedback A/Ds are connected with the central processing unit;
The feedback detection resistance, for generating feedback pressure drop under the action of the exciting current signal;
The feedback amplifier, for being amplified to the feedback pressure drop;
The feedback A/Ds, for the amplified feedback pressure drop to be converted into digital pressure drop;
The central processing unit, for when judging that the digital pressure drop is less than preset steady state value, increasing the detection Signal, to increase the size of the exciting current.
With reference to first aspect, an embodiment of the present invention provides the 8th kind of possible embodiments of first aspect, wherein institute The number for stating test electrode is even number.
Second aspect, an embodiment of the present invention provides multichannel Electrical Impedance Tomography Systems, including:Host computer and above-mentioned Any one of them multichannel electrical impedance tomography circuit;
The host computer is connected or is wirelessly connected by USB line with the multichannel electrical impedance tomography circuit;
The host computer is monitored in real time for the working condition to the multichannel electrical impedance tomography circuit.
Multichannel electrical impedance tomography circuit provided in an embodiment of the present invention and system, wherein the multichannel electrical impedance Fault imaging circuit includes:Central processing unit, current excitation module, measurement module and back end processing module, in multichannel electricity In impedance tomography circuit, the number of back end processing module is multiple, and above-mentioned central processing unit, measures current excitation module Module and each back end processing module are sequentially connected, also, each back end processing module is connected with central processing unit, i.e., multiple Back end processing module is all independent to be connected together to multiple signal returns to the channel of central processing unit, above-mentioned survey with central processing unit It includes multiple test electrodes to measure module, also, multiple test electrodes are evenly spaced in a plane, each test electricity therein Extremely it is connected with a back end processing module, in use, current excitation module is used to receive central processing unit hair After the detectable signal gone out, any two test electrode into measurement module sends out exciting current signal, is tested to open Journey, remaining test electrode are used to generate multichannel driving voltage signal under the action of exciting current signal, i.e., tested body is in quilt The driving voltage signal generated after above-mentioned exciting current signal stimulus, later, each back end processing module are used for being attached thereto The driving voltage signal that generates of test electrode be amplified after processing and analog-to-digital conversion and generate conversion results signal, to send to Central processing unit carries out imaging, by above-mentioned processing procedure, realizes single test electrode and individual back-end processing mould Block is connected, and the effect to work, in this way, multiple test electrodes in test process can be simultaneously by the excitation measured electricity Stream signal return is handled to central processing unit, compared with existing processing mode, the multichannel electrical impedance tomography electricity Road can realize high speed and high-precision signal processing, and then improve the efficiency of test.
Other features and advantages of the present invention will illustrate in the following description, also, partly become from specification It obtains it is clear that understand through the implementation of the invention.The purpose of the present invention and other advantages are in specification, claims And specifically noted structure is realized and is obtained in attached drawing.
To enable the above objects, features and advantages of the present invention to be clearer and more comprehensible, preferred embodiment cited below particularly, and coordinate Appended attached drawing, is described in detail below.
Description of the drawings
It, below will be to specific in order to illustrate more clearly of the specific embodiment of the invention or technical solution in the prior art Embodiment or attached drawing needed to be used in the description of the prior art are briefly described, it should be apparent that, in being described below Attached drawing is some embodiments of the present invention, for those of ordinary skill in the art, before not making the creative labor It puts, other drawings may also be obtained based on these drawings.
Fig. 1 shows the connection figure for the multichannel electrical impedance tomography circuit that the embodiment of the present invention is provided;
Fig. 2 shows the connection diagrams for the multichannel electrical impedance tomography circuit that the embodiment of the present invention is provided;
Fig. 3 shows the structure connection figure for the multichannel Electrical Impedance Tomography System that the embodiment of the present invention is provided.
Icon:1- central processing units;2- current excitation modules;3- encourages assurance module;4- measurement modules;5- back-end processings Module.
Specific implementation mode
Below in conjunction with attached drawing in the embodiment of the present invention, technical solution in the embodiment of the present invention carries out clear, complete Ground describes, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Usually exist The component of the embodiment of the present invention described and illustrated in attached drawing can be arranged and be designed with a variety of different configurations herein.Cause This, the detailed description of the embodiment of the present invention to providing in the accompanying drawings is not intended to limit claimed invention below Range, but it is merely representative of the selected embodiment of the present invention.Based on the embodiment of the present invention, those skilled in the art are not doing The every other embodiment obtained under the premise of going out creative work, shall fall within the protection scope of the present invention.
In existing bioelectrical impedance tomography device, in general, two output switches only are arranged in emitting portion, use To send pumping signal to test electrode;Two input switches are arranged in detection part, and being used for will be aitiogenic to pumping signal Return path signal (for example, driving voltage signal etc.) returns to processor one by one.Due in bioelectrical impedance tomography device Number of poles is more, the switch that the signal in above-mentioned multiple electrodes can not simultaneously Jing Guo emitting portion and detection part, Zhi Nengyi One transmission, in this way, causing the speed of detection slower, measuring accuracy can not also ensure, although imaging still has functionality, limit Its application range is made.
Based on this, an embodiment of the present invention provides multichannel electrical impedance tomography circuit and systems, below by implementation Example is described.
Embodiment 1
Referring to Fig. 1 and Fig. 2, the multichannel electrical impedance tomography circuit that the present embodiment proposes specifically includes:Central processing Device 1, current excitation module 2, excitation assurance module 3, measurement module 4 and back end processing module 5 need to illustrate herein It is that the number of back end processing module is multiple, by the way that multiple back end processing modules are arranged so that the passback being connected with test module Par wise irrelevance between channel, each independent back end processing module are used for handling the return path signal in a test process, when having When multiple test signals generate simultaneously, you can return to central processing unit simultaneously by above-mentioned each test module and further locate Reason.
Connection relation under lower mask body is introduced between above-mentioned modules:Above-mentioned central processing unit, excitation assurance module, Current excitation module, measurement module and each back end processing module are sequentially connected, also, each back end processing module is and central Processor is connected, wherein and measurement module includes multiple test electrodes, and multiple test electrodes are evenly spaced in a plane, and And each test electrode is connected with a back end processing module, needs to illustrate, above-mentioned measurement module includes more A test electrode, in general, the number of test electrode is even number, to facilitate optional two of which as the electrode of input, In the present embodiment, the number for testing electrode is 16.When in use, in order to ensure that test signal can be uniformly distributed, multiple surveys Examination electrode is evenly spaced in a plane, and each electrode of testing is connected with a back end processing module, in this way, a test Electrode and a back end processing module connect into independent return path.
After test is opened, current excitation module is used for after receiving the detectable signal that central processing unit is sent out, to survey Amount mould any two test electrode in the block sends out current signal.Here, central processing unit sends out detectable signal to measurement module It is the generation for promoting current signal in measurement module, i.e., test process is opened with this.Assurance module is encouraged to be used for current signal It is adjusted to steady state value, exciting current signal is generated according to steady state value, i.e., exciting current signal is ensured by the setting of steady state value Size.Due to, include multiple test electrodes in measurement module, also, the effect of each test electrode is identical, it is each to test The location of electrode is also identical.In this way, during the test, optionally any two of which test electrode it can be used as reception and swash The test electrode for encouraging current signal, signal is as uniform as possible in order to detect, and generally selects the test electrode of two opposite ends.In general, Pumping signal is single sine wave, to obtain the high sensitivity measured;Or the overlaid waveforms of limited multiple sine waves, to measure mesh Target frequency characteristic, compared with the current signals such as square wave, the variation of sine wave excitation currents signal is more steady, can improve measurement Sensitivity.All any twos test electrode calculates a test until all receiving exciting current signal in above-mentioned test process Process when usually used, can repeat above-mentioned test process (at least twice), then the result tested every time is done one linearly Fitting.
In this way, remaining test electrode is used to generate multichannel driving voltage signal under the action of exciting current signal, surveying After examination person receives above-mentioned exciting current signal, position that can be where testing electrode generates reaction, and is being placed on the position Remaining test electrode on generate multichannel driving voltage signal, i.e., one test electrode on generate driving voltage signal all the way.
Later, after each back end processing module receives driving voltage signal, each back end processing module is to phase therewith The driving voltage signal that test electrode even generates generates multiple conversion results signals accordingly after being carried out at the same time amplification and conversion, And it sends central processing unit to and is imaged.Since the setting of multiple back end processing modules can be to multichannel driving voltage signal Parallel processing is carried out, to improve the processing capacity that driving voltage signal is amplified and is converted.
Include the detection being sequentially connected in the multichannel electrical impedance tomography circuit, in each back end processing module Selecting switch, preamplifier, bandpass filter, logafier and A/D digital quantizers detect and select switch connection and survey The connected preamplifier of electrode is tried, i.e., before circuit is not used, is detected and selected between switch and preamplifier in disconnection shape State, also, multiple switches that detect and select are connected with central processing unit, in the circuit in use, multiple detect and select switch Connection for being connected to after the return path signal for receiving central processing unit between remaining test electrode and preamplifier, with shape At the connection relation one by one between test electrode and preamplifier.In general, return path signal is to send out spy by central processing unit It is generated after delay a period of time after survey signal, the length of specific a period of time can carry out flexibly according to the concrete condition of circuit Setting.
Above-mentioned preamplifier is used for carrying out Linear Amplifer to driving voltage signal, obtains the first amplification voltage signal, with Ensure the integrality of driving voltage signal fed back.Later, amplify voltage signal with bandpass filter pair first to filter Wave obtains band logical voltage signal, by the use of bandpass filter, effectively reduces the relatively low frequency in driving voltage signal waveform Part and higher-frequency part, the reason is that, it is relatively more compared with the interference that low frequency part and higher-frequency part are adulterated, pass through bandpass filtering More live parts can be got.Later, logarithmic amplification is carried out to band logical voltage signal with logafier, obtains the second amplification Voltage signal, traditional design are all the linear amplifiers of variable gain, due to the shape of a saddle logarithm point of electrical impedance imaging signal Cloth, can be to the measurement of useful signal higher resolution using logafier.And a small amount of big signal still can ensure phase To resolution ratio.Logafier can provide small signal bigger gain;And smaller gain is provided big signal. In the present embodiment, since the test electrode close to excitation end may obtain the detection signal of the about half of driving voltage signal. And the signal obtained apart from the test electrode of excitation end farther out is exponentially decayed.Logafier will be far from the excitation electricity at excitation end Signal is pressed to carry out the amplification of more large gain, to substantially increase the resolution ratio of signal.Getting above-mentioned driving voltage signal Afterwards, amplify voltage signal with A/D digital quantizers pair second and carry out analog-to-digital conversion, digital voltage signal is obtained, so as to center Processor is further processed digital voltage signal.
Due to the parameter meeting and standard parameter that electronic component in circuit etc. is made under different manufacturing process Difference, moreover, the connection relation between electronic component can also influence the accuracy of configured transmission.It is tested on electrode in view of being added in Exciting current signal it is fainter, in order to reduce influence of the circuit to test process itself, reduce and use A/D digital quantizers Carry out the error in transfer process.Further include the first calibrating resistance in above-mentioned each back end processing module, the first calibrating resistance One end is connected with the first calibrating resistance in adjacent back end processing module, until the first calibration in all back end processing modules Resistance, which is sequentially connected, to be circularized, and is continued for testing the number of electrode and be 16, and exactly the 1st detects and selects switch connection First calibrating resistance is connect with the 2nd the first calibrating resistance for detecting and selecting switch closed on, and so on, the 16th detection choosing The first calibrating resistance that the 1st the first calibrating resistance for detecting and selecting switch for selecting switch detects and selects switch with the 1st is connect, the The other end of one calibrating resistance is connected with switch is detected and selected, and in use, the first calibrating resistance is used in central processing Device generates first voltage to detecting and selecting switch and send out under the excitation of the first calibration signal, central processing unit be used to measure the Difference between one voltage and the first normal voltage is denoted as the first measured error signal.
Since, circuit is to the generally linear variation of response of pumping signal, rather than fixed value.Therefore, each rear end Further include the second calibrating resistance in processing module, needs to illustrate, the resistance of the second calibrating resistance and the first calibrating resistance Value is different, i.e., weighs its error, one end of the second calibrating resistance and adjacent back-end processing by the resistance of different resistance values Mould the second calibrating resistance in the block is connected, and is circularized until the second calibrating resistance in all back end processing modules is sequentially connected, The other end of second calibrating resistance is connected with switch is detected and selected, and in use, the second calibrating resistance can be in centre Reason device generates second voltage to detecting and selecting switch and send out under the excitation of the second calibration signal, central processing unit will measure second Difference between voltage and the second normal voltage is denoted as the second measured error signal.
Also, central processing unit calculates above-mentioned modulus according to above-mentioned first measured error signal and the second measured error signal Conversing circuits (the analog-to-digital conversion circuit be include A/D digital quantizers, the first calibrating resistance and the second calibrating resistance circuit) Interference value, for example, sending out the excitation (for example, 1mA electric currents) of the first calibration signal to switch is detected and selected in central processing unit Lower generation first voltage, it is assumed that 1mA is Vr1=1V under 1k Ohmic resistances, and actual measured value is Vad1=1.08V;Resistance 100 ohm of generation Vr2=0.1V, and actual measured value is Vad2=0.11V;Bring equation Vad=a*Vr+b into;Calculate a= (Vad1-Vad2)/(Vr1-Vr2)=1.078;B=1.08-1.078*1=0.002;Vad=1.078*V+0.002, practical electricity V=(Vad-0.002)/1.078 is pressed, is measured so just more accurate.In addition, it is necessary to illustrate, when actual implementation, is It is measured twice, and the result by measuring twice does an once linear fitting to determine final measurement error.
In addition, in the present embodiment current excitation module include the current source generator being sequentially connected, exciting amplifier and Selecting switch is encouraged, also, selecting switch is encouraged to be connected with central processing unit, in implementation process, current source generator is connecing Exciting current is generated after receiving the detectable signal that central processing unit is sent out, uses current source generator to be sent out as detectable signal here Raw device, can ensure the stability of electric current during the test, avoid remaining electronic component to the electric current in test It influences.Later, exciting amplifier obtains exciting current signal, has with guarantee sufficiently large for being amplified to exciting current Electric current reaches human body and is tested.Also, excitation selecting switch is connected to any two test electricity under the control of central processing unit Connection between pole and exciting amplifier.By encouraging the setting of selecting switch that can effectively respond the control of central processing unit System, and two are selected to be tested from above-mentioned 16 test electrodes.
In addition, being tested to further ensure that sufficiently large electric current reaches human body, excitation in the present embodiment is protected Barrier module includes feedback detection resistance, feedback amplifier and feedback A/Ds, the connection between above-mentioned all parts Relationship is:Exciting amplifier and excitation selecting switch are connected with the input terminal of feedback amplifier, and feedback detection resistance is connected in parallel on On the input terminal of feedback amplifier, feedback amplifier is connected with feedback A/Ds, feedback A/Ds and central processing Device is connected, in use, feedback detection resistance is used to generate feedback pressure drop under the action of exciting current signal, feedback amplifier is used It is amplified in feedback pressure drop, feedback A/Ds are used to amplified feedback pressure drop being converted into digital pressure drop, center Processor is used to, when the digital pressure drop of judgement is less than preset steady state value, increase detectable signal, to increase the size of exciting current, The numerical value specifically adjusted can be adjusted according to the feedback pressure drop measured in real time, so as to further ensure exciting current signal Numerical value it is sufficiently large, keep test process safe and effective.
Since meeting is by the exciting current signal in circuit during encouraging selecting switch to carry out open and close It influences, for example, when excitation selecting switch be closed two-way therein come when gating the test electrode being attached thereto, other 14 tunnel Encourage selecting switch can be during above-mentioned two-way is closed by rush of current.In the present embodiment, selecting switch is encouraged Number is two, also, two excitation selecting switch series connection, i.e., only there are two could will be encouraged when excitation selecting switch is all connected Current signal transfer gives test electrode.It needs to illustrate, one of excitation selecting switch ground connection, by exciting current The influence access the earth generated when signal flows through.In specific implementation process, unearthed excitation selecting switch be used for appoint During two test electrodes of meaning send out exciting current signal, level-one isolation, i.e. any two are carried out to remaining test electrode When testing the excitation selecting switch conducting corresponding to electrode, there is exciting current signal warp in any two test electrode of conducting It crosses, the excitation selecting switch corresponding to remaining test electrode does not turn on, although can be influenced by the exciting current signal passed through, But level-one isolation is effectively carried out due to not turning on.On this basis, the excitation selecting switch of ground connection be used for appoint During two test electrodes of meaning send out exciting current signal, two level isolation is carried out to remaining test electrode, i.e., it is above-mentioned not lead Excitation selecting switch corresponding to remaining logical test electrode the excitation selecting switch of concatenated ground connection can be by the sharp of process The influence for encouraging current signal further weakens, to ensure the measuring accuracy of test electrode.
In conclusion multichannel electrical impedance tomography circuit provided in this embodiment includes:Central processing unit, electric current swash Encourage module, excitation assurance module, measurement module and back end processing module, wherein the number of back end processing module is multiple, center Processor, excitation assurance module, current excitation module, measurement module and each back end processing module are sequentially connected, also, each Back end processing module is connected with central processing unit, wherein measurement module includes multiple test electrodes, also, multiple tests are electric Pole is evenly spaced in a plane, and each electrode of testing is connected with a back end processing module, in use, electric current Encourage module after receiving the detectable signal that central processing unit is sent out, any two test electrode into measurement module is sent out Current signal, excitation assurance module are used for current signal being adjusted to steady state value, and exciting current signal is generated according to steady state value, this Sample, remaining test electrode generate multichannel driving voltage signal under the action of exciting current signal, subsequently carry out parallel processing, i.e., The driving voltage signal that each back end processing module generates the test electrode being attached thereto generates after being amplified and converting to be turned Change consequential signal, be imaged with sending central processing unit to, by above-mentioned processing procedure, accelerate bio-electrical impedance tomography at As the test speed of device, its measuring accuracy is improved.
Embodiment 2
Referring to Fig. 3, present embodiments providing multichannel Electrical Impedance Tomography System includes:Host computer and any of the above-described Multichannel electrical impedance tomography circuit, need exist for illustrating, host computer and multichannel electrical impedance tomography Circuit is connected or is wirelessly connected by USB line, specifically, between host computer and multichannel electrical impedance tomography circuit When distance is closer, connected by USB line, it is convenient and efficient;When between host computer and multichannel electrical impedance tomography circuit away from From farther out either line inconvenience when, by being wirelessly connected, in this way, host computer can be to multichannel electrical impedance tomography electricity The working condition on road is monitored in real time, in order to which manager can observe multichannel electrical impedance tomography circuit in real time Working condition.
In conclusion multichannel Electrical Impedance Tomography System provided in this embodiment includes:Host computer and any of the above-described Multichannel electrical impedance tomography circuit, host computer connected by USB line with multichannel electrical impedance tomography circuit or Person is wirelessly connected, and in use, host computer is used to carry out the working condition of multichannel electrical impedance tomography circuit real When monitor, consequently facilitating supervision and oversight.
It is apparent to those skilled in the art that for convenience and simplicity of description, the system of foregoing description Specific work process, can refer to previous embodiment in corresponding process, details are not described herein.
In addition, in the description of the embodiment of the present invention unless specifically defined or limited otherwise, term " installation ", " phase Even ", " connection " shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or be integrally connected;It can Can also be electrical connection to be mechanical connection;It can be directly connected, can also indirectly connected through an intermediary, Ke Yishi Connection inside two elements.To those skilled in the art, it can understand above-mentioned term in the present invention with concrete condition Concrete meaning.
In the description of the present invention, it should be noted that term "center", "upper", "lower", "left", "right", "vertical", The orientation or positional relationship of the instructions such as "horizontal", "inner", "outside" be based on the orientation or positional relationship shown in the drawings, merely to Convenient for the description present invention and simplify description, do not indicate or imply the indicated device or element must have a particular orientation, With specific azimuth configuration and operation, therefore it is not considered as limiting the invention.
Finally it should be noted that:Embodiment described above, only specific implementation mode of the invention, to illustrate the present invention Technical solution, rather than its limitations, scope of protection of the present invention is not limited thereto, although with reference to the foregoing embodiments to this hair It is bright to be described in detail, it will be understood by those of ordinary skill in the art that:Any one skilled in the art In the technical scope disclosed by the present invention, it can still modify to the technical solution recorded in previous embodiment or can be light It is readily conceivable that variation or equivalent replacement of some of the technical features;And these modifications, variation or replacement, do not make The essence of corresponding technical solution is detached from the spirit and scope of technical solution of the embodiment of the present invention, should all cover the protection in the present invention Within the scope of.Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.

Claims (10)

1. a kind of multichannel electrical impedance tomography circuit, which is characterized in that including:Central processing unit, swashs at current excitation module Encourage assurance module, measurement module and back end processing module, wherein the number of the back end processing module is multiple;
The central processing unit, the excitation assurance module, the current excitation module, the measurement module and it is each it is described after End processing module is sequentially connected, and, each back end processing module is connected with the central processing unit, wherein the survey It includes multiple test electrodes to measure module, and multiple test electrodes are evenly spaced in a plane, and, each test electricity Extremely it is connected with a back end processing module;
The current excitation module, for after receiving the detectable signal that the central processing unit is sent out, to the measurement mould Electrode is tested described in any two in the block and sends out current signal, until all test electrodes all receive the electric current Until signal;
The excitation assurance module generates excitation electricity for the current signal to be adjusted to steady state value according to the steady state value Flow signal;
Remaining described test electrode, for generating multichannel driving voltage signal under the action of the exciting current signal;
Each back end processing module, the driving voltage signal for being generated to the test electrode being attached thereto into Conversion results signal is generated after row amplification and conversion, is imaged with sending the central processing unit to.
2. multichannel electrical impedance tomography circuit according to claim 1, which is characterized in that each back-end processing In module switch, preamplifier, bandpass filter, logafier and A/D numbers are detected and selected including what is be sequentially connected Converter;
It is described to detect and select switch, for being connected to the preamplifier being connected with the test electrode;
The preamplifier obtains the first amplification voltage signal for carrying out Linear Amplifer to the driving voltage signal;
The bandpass filter obtains band logical voltage signal for being filtered to the first amplification voltage signal;
The logafier obtains the second amplification voltage signal for carrying out logarithmic amplification to the band logical voltage signal;
The A/D digital quantizers obtain digital voltage letter for carrying out analog-to-digital conversion to the second amplification voltage signal Number.
3. multichannel electrical impedance tomography circuit according to claim 2, which is characterized in that detected and selected described in multiple Switch is connected with the central processing unit;
Switch is detected and selected described in multiple, is used to be connected to described in remaining after the return path signal for receiving the central processing unit Test the connection between electrode and the preamplifier.
4. multichannel electrical impedance tomography circuit according to claim 2, which is characterized in that each back-end processing It further include the first calibrating resistance in module;
One end of first calibrating resistance is connected with first calibrating resistance in the adjacent back end processing module, directly Be sequentially connected and circularize to first calibrating resistance in all back end processing modules, first calibrating resistance it is another One end is connected with the switch that detects and selects;
First calibrating resistance, for sending out the first calibration signal to the switch that detects and selects in the central processing unit Excitation is lower to generate first voltage;
The central processing unit, for the difference between the first voltage measured and the first normal voltage to be denoted as the first survey Measure error signal.
5. multichannel electrical impedance tomography circuit according to claim 4, which is characterized in that each back-end processing Further include the second calibrating resistance in module, wherein second calibrating resistance is different from the resistance value of the first calibrating resistance;
One end of second calibrating resistance is connected with second calibrating resistance in the adjacent back end processing module, directly Be sequentially connected and circularize to second calibrating resistance in all back end processing modules, second calibrating resistance it is another One end is connected with the switch that detects and selects;
Second calibrating resistance, for sending out the second calibration signal to the switch that detects and selects in the central processing unit Excitation is lower to generate second voltage;
The central processing unit, for the difference between the second voltage measured and the second normal voltage to be denoted as the second survey Measure error signal.
6. multichannel electrical impedance tomography circuit according to claim 1, which is characterized in that the current excitation module Including be sequentially connected current source generator, exciting amplifier and excitation selecting switch, and, the excitation selecting switch with it is described Central processing unit is connected;
The current source generator, for generating exciting current after receiving the detectable signal that the central processing unit is sent out;
The exciting amplifier obtains the exciting current signal for being amplified to the exciting current;
The excitation selecting switch, for being connected to test electrode and institute described in any two under the control of the central processing unit State the connection between exciting amplifier.
7. multichannel electrical impedance tomography circuit according to claim 6, which is characterized in that the excitation selecting switch Number be two, and, two excitation selecting switch series connection, one of them described excitation selecting switch is grounded;
The unearthed excitation selecting switch, in the mistake for sending out exciting current signal to test electrode described in any two Cheng Zhong carries out level-one isolation to remaining described described test electrode;
The excitation selecting switch of ground connection, in the process for sending out exciting current signal to test electrode described in any two In, two level isolation is carried out to remaining described described test electrode.
8. multichannel electrical impedance tomography circuit according to claim 6, which is characterized in that the excitation assurance module Including feedback detection resistance, feedback amplifier and feedback A/Ds;
The exciting amplifier and the excitation selecting switch are connected with the input terminal of the feedback amplifier, the feedback inspection Measuring resistance is connected in parallel on the input terminal of the feedback amplifier, and the feedback amplifier is connected with the feedback A/Ds, The feedback A/Ds are connected with the central processing unit;
The feedback detection resistance, for generating feedback pressure drop under the action of the exciting current signal;
The feedback amplifier, for being amplified to the feedback pressure drop;
The feedback A/Ds, for the amplified feedback pressure drop to be converted into digital pressure drop;
The central processing unit, for when judging that the digital pressure drop is less than preset steady state value, increasing the detectable signal, To increase the size of the exciting current.
9. multichannel electrical impedance tomography circuit according to claim 1, which is characterized in that of the test electrode Number is even number.
10. a kind of multichannel Electrical Impedance Tomography System, which is characterized in that including:Host computer and such as claim 1-9 are any Multichannel electrical impedance tomography circuit described in;
The host computer is connected or is wirelessly connected by USB line with the multichannel electrical impedance tomography circuit;
The host computer is monitored in real time for the working condition to the multichannel electrical impedance tomography circuit.
CN201810476960.3A 2018-05-17 2018-05-17 Multichannel electrical impedance tomography circuit and system Pending CN108577838A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114366068A (en) * 2021-12-29 2022-04-19 杭州永川科技有限公司 Modularized high-speed electrical impedance imaging device and using method

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101199418A (en) * 2006-12-12 2008-06-18 深圳迈瑞生物医疗电子股份有限公司 Brain impedance detection circuitry and EEG checking device
CN104007322A (en) * 2014-06-12 2014-08-27 中国人民解放军第四军医大学 High-precision data acquisition system for electrical impedance imaging
CN204188204U (en) * 2014-11-14 2015-03-04 成都汉康信息产业有限公司 Based on the Urban Data harvester of double copies
CN104605851A (en) * 2015-02-16 2015-05-13 天津大学 Electrical impedance tomography (EIT) system data acquisition method
CN104983422A (en) * 2015-07-17 2015-10-21 南京邮电大学 Electrical impedance tomography device of electrodes 32
CN105652756A (en) * 2016-03-21 2016-06-08 成都爆米花信息技术有限公司 Safe multichannel data collection system
CN105652755A (en) * 2016-03-21 2016-06-08 成都爆米花信息技术有限公司 Safe and improved multichannel data collection system
CN105943045A (en) * 2016-05-18 2016-09-21 上海交通大学 High-precision bio-electrical impedance measuring system and method for body composition analysis
CN105976411A (en) * 2016-05-18 2016-09-28 中国人民解放军第四军医大学 Prepositioned measuring module for electrical impedance tomography imaging data acquisition system and alignment and calibration method
CN106526499A (en) * 2016-11-04 2017-03-22 北京无线电计量测试研究所 Highly-stable current source examination method and system
CN107320101A (en) * 2017-06-20 2017-11-07 南京邮电大学 A kind of multifrequency electric impedance imaging system

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101199418A (en) * 2006-12-12 2008-06-18 深圳迈瑞生物医疗电子股份有限公司 Brain impedance detection circuitry and EEG checking device
CN104007322A (en) * 2014-06-12 2014-08-27 中国人民解放军第四军医大学 High-precision data acquisition system for electrical impedance imaging
CN204188204U (en) * 2014-11-14 2015-03-04 成都汉康信息产业有限公司 Based on the Urban Data harvester of double copies
CN104605851A (en) * 2015-02-16 2015-05-13 天津大学 Electrical impedance tomography (EIT) system data acquisition method
CN104983422A (en) * 2015-07-17 2015-10-21 南京邮电大学 Electrical impedance tomography device of electrodes 32
CN105652756A (en) * 2016-03-21 2016-06-08 成都爆米花信息技术有限公司 Safe multichannel data collection system
CN105652755A (en) * 2016-03-21 2016-06-08 成都爆米花信息技术有限公司 Safe and improved multichannel data collection system
CN105943045A (en) * 2016-05-18 2016-09-21 上海交通大学 High-precision bio-electrical impedance measuring system and method for body composition analysis
CN105976411A (en) * 2016-05-18 2016-09-28 中国人民解放军第四军医大学 Prepositioned measuring module for electrical impedance tomography imaging data acquisition system and alignment and calibration method
CN106526499A (en) * 2016-11-04 2017-03-22 北京无线电计量测试研究所 Highly-stable current source examination method and system
CN107320101A (en) * 2017-06-20 2017-11-07 南京邮电大学 A kind of multifrequency electric impedance imaging system

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
尤富生: "电阻抗断层成像硬件系统", 《国外医学生物医学工程分册》 *
徐佳芝, 李颖: "《生物医学电阻抗成像技术》", 30 June 2010, 机械工业出版社 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114366068A (en) * 2021-12-29 2022-04-19 杭州永川科技有限公司 Modularized high-speed electrical impedance imaging device and using method
CN114366068B (en) * 2021-12-29 2022-08-09 杭州永川科技有限公司 Modularized high-speed electrical impedance imaging device and using method

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Application publication date: 20180928