CN105943033A - A wearable experimental animal electroencephalogram collection device - Google Patents
A wearable experimental animal electroencephalogram collection device Download PDFInfo
- Publication number
- CN105943033A CN105943033A CN201610361660.1A CN201610361660A CN105943033A CN 105943033 A CN105943033 A CN 105943033A CN 201610361660 A CN201610361660 A CN 201610361660A CN 105943033 A CN105943033 A CN 105943033A
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- CN
- China
- Prior art keywords
- waistcoat
- acquisition device
- brain wave
- wave acquisition
- laboratory animal
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/369—Electroencephalography [EEG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6802—Sensor mounted on worn items
- A61B5/6804—Garments; Clothes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2503/00—Evaluating a particular growth phase or type of persons or animals
- A61B2503/40—Animals
Abstract
The invention provides a wearable experimental animal electroencephalogram collection device comprising an electroencephalogram recording electrode connected to a head; the electroencephalogram recording electrode establishes connection with a signal collector via a transmission line; the signal collector is fixed on a waistcoat worn by an experimental animal; the other end of the signal collector establishes connection with a signal receiver; the waistcoat is provided with a first upper limb passing hole and a second upper limb passing hole; the inner surface of one end of the waistcoat is provided with a hook-and-loop fastener hook component and the outer surface of the other end of the waistcoat is provided with a hook-and-loop fastener loop component; the hook-and-loop fastener hook component is fastened to the hook-and-loop fastener loop component; the waistcoat is provided with a positive V-shaped circular arc section and an inverse V-shaped circular arc section. The wearable experimental animal electroencephalogram collection device is small in size and light in weight, reduces stress on the head of an experimental animal and is conducive to wound healing; detection workers can control the device conveniently; an electroencephalogram signal collection process is not liable to be disturbed by external environment, so that the collection of electroencephalogram signals of an experimental animal can last for a long time.
Description
Technical field
The present invention relates to technical field of medical instruments, specifically, be a kind of wearable laboratory animal brain wave acquisition device.
Background technology
In the laboratory animal experimentation of life science, the element that the collection of laboratory animal EEG signals and monitoring are studied as laboratory animal Electrophysiology, always one highly important technology.There is electrical phenomena at cerebral cortex or scalp surface in the bioelectrical activity of cranial nerve cell, contains a large amount of physiology and disease information in EEG signals, and medical experiment usually carries out eeg signal acquisition to animal, in order to analysis of disease provides diagnosis basis.
At present, the brain wave acquisition device of laboratory animal is all that recording electrode, signal receiver are fixed on skull together with emitter.So have the following disadvantages and defect in animal brain wave acquisition.
First, recording electrode, signal receiver and emitter are also secured on animal skull by animal brain electricity harvester, the open wound that animal head cannot heal can be caused, wound cannot heal, then can cause infection, even dead, this is unfavorable for testing staff's collection to animal brain electricity, can cause iatrogenic loss and waste simultaneously.
Secondly, being fixed on skull harvester on animal head, volume is big, heavy.It is only the decline bringing inconvenience and comfort level in the action for the animal that the build such as rat, Cavia porcellus is bigger, the laboratory animal that the builds such as mice are less is even affected to the main activitys such as its feed drinking-water and bring bigger pressure to its head.
Additionally, brain wave acquisition device is easily by external environmental interference, during to animal brain wave acquisition, usually because of external interference, cause the failure of animal brain electrical signal collection, and the animal such as laboratory animal such as rat or mice, all there is active habit, when the brain electric installation used in prior art is arranged on rat or mice skull, rat or mice are because liking movable, the associated components making brain electric installation easily comes off, eeg signal acquisition is disturbed, and rat or mice belong to responsive type animal, when feeling that head is uncomfortable, brain wave acquisition device can be ceaselessly perturbed with cat's paw, brain wave acquisition device was not in being perturbed by cat's paw, interference effect is big, it is unfavorable for the collection of EEG signals.
Furthermore, because rat or mouse head are less, and structure is special, similar taper, and when testing staff just installs brain electric installation of the prior art, operation inconvenience, wastes time and energy.
In sum, need that a kind of volume is little badly, alleviate head pressure, fixed effect is definite, prevent wearable laboratory animal brain wave acquisition device crawled, that external interference is little.And yet there are no report about this brain wave acquisition device.
Summary of the invention
It is an object of the invention to for deficiency of the prior art, it is provided that a kind of volume is little, alleviate head pressure, fixed effect is definite, prevent wearable laboratory animal brain wave acquisition device crawled, that external interference is little, easy to operate.
For achieving the above object, the present invention adopts the technical scheme that:
A kind of wearable laboratory animal brain wave acquisition device, described brain wave acquisition device includes the eeg recording electrode being connected to head, and described eeg recording electrode is connected with signal picker foundation by transmission line；Described signal picker is fixed on the waistcoat that laboratory animal is dressed；The described signal picker other end is set up with signal receiver and is connected；Described waistcoat is provided with the first upper limb perforation and the perforation of the second upper limb；Described waistcoat one end inner surface is provided with sub-VELCRO；Described waistcoat other end outer surface is provided with female VELCRO；The described female VELCRO of sub-magic laminating is bonded to each other；Described waistcoat is provided with positive V-arrangement arc section and inverted v-shape arc section.
Further, the first described upper limb perforation is consistent with the second upper limb perforation shape.
Further, the first described upper limb perforation and the perforation of the second upper limb are symmetric.
Further, described waistcoat is splayed.
Further, the throat position of laboratory animal it is positioned under described positive V-arrangement arc section wearing state.
Further, it is positioned under described inverted v-shape arc section wearing state at the abdominal part top position of laboratory animal.
Further, described waistcoat outer surface is provided with signal picker fixing band and signal receiver fixing band.
Further, described signal picker fixing band and signal receiver fixing band are Integratively formed with waistcoat.
Further, the elastomeric material of the material of described waistcoat.
Further, described waistcoat outer surface is additionally provided with signal picker fixed body and signal receiver fixed body.
The invention has the advantages that:
1, a kind of Wearable brain electricity laboratory animal harvester of the present invention, volume is little, lightweight, alleviate the pressure of laboratory animal head, being conducive to wound healing, testing staff is easy to control, simultaneously during eeg signal acquisition, it is susceptible to external environmental interference, it is possible to for a long time laboratory animal is gathered EEG signals；
2, only having eeg recording electrode to be fixed on animal head, signal picker is not mounted to animal head, is not the most embedded in back part of animal subcutaneous, but is worn on animal with waistcoat, had the most both reduced the injury to animal and stimulation, and had facilitated again testing staff to operate；
3, signal picker and signal receiver are each attached on the waistcoat at corresponding laboratory animal back, so laboratory animal is in active procedure, the signal picker being fixed on the waistcoat of back and signal receiver can not be perturbed by its extremity, it is to avoid eeg signal acquisition failure；
4, being provided with waistcoat, material preferred elastomeric material, such elasticity is adjustable so that waistcoat is fixing definite in laboratory animal, decreases the external environment interference to EEG signals, the beneficially collection of EEG signals；
5, waistcoat is provided with positive V-arrangement arc section, with inverted v-shape arc section, this design is to be designed according to the body structure of laboratory animal, position near the throat of laboratory animal it is positioned under positive V-arrangement arc section wearing state, it can be avoided that laboratory animal is strangled to obtain tension, affect breathing and the feed etc. of laboratory animal, be positioned at the abdominal part top position of laboratory animal under inverted v-shape arc section wearing state, the abdominal part that can avoid laboratory animal is strangled to obtain tension, affects it and digests normally；
6, described waistcoat outer surface is additionally provided with signal picker fixing band and signal receiver fixing band, can be fixed signal picker and signal receiver by fixing band；
7, being provided with signal picker fixed body and signal receiver fixed body, be difficult to slip, the interface of each parts is completely embedded.
Accompanying drawing explanation
Accompanying drawing 1 is the one wearable laboratory animal brain wave acquisition device block diagram of the present invention.
Accompanying drawing 2 is that the one wearable laboratory animal brain wave acquisition device of the present invention uses status architecture schematic diagram.
Accompanying drawing 3 is waistcoat inner surface structure schematic diagram.
Accompanying drawing 4 is waistcoat outer surface structure schematic diagram.
Accompanying drawing 5 is another waistcoat outer surface structure schematic diagram of the present invention.
Detailed description of the invention
The detailed description of the invention provided the present invention below in conjunction with the accompanying drawings elaborates.
The reference and the ingredient that relate in accompanying drawing are as follows:
1. laboratory animal 11. head
12. back 13. eeg recording electrodes
14. signal picker 15. signal receivers
16. transmission line 2. waistcoats
21. first upper limb perforation 22. second upper limb perforation
23. positive V-arrangement arc section 24. inverted v-shape arc sections
The female VELCRO of 25. sub-VELCRO 26.
27. signal picker fixing band 28. signal receiver fixing bands
29. signal picker fixed body 291. signal receiver fixed bodies
Embodiment 1
Refer to the one wearable laboratory animal 1 brain wave acquisition device block diagram that Fig. 1 and Fig. 2, Fig. 1 are the present invention.Fig. 2 is that the one wearable laboratory animal 1 brain wave acquisition device of the present invention uses status architecture schematic diagram.A kind of wearable laboratory animal 1 brain wave acquisition device.Described brain wave acquisition device includes that the eeg recording electrode 13 being connected to head 11, described eeg recording electrode 13 are connected with signal picker 14 foundation by transmission line 16；Described signal picker 14 is fixed on the waistcoat 2 that laboratory animal 1 is dressed；Described signal picker 14 other end is set up with signal receiver 15 and is connected.
Refer to Fig. 3 and Fig. 4, Fig. 3 is waistcoat 2 inner surface structure schematic diagram.Fig. 4 is waistcoat 2 outer surface structure schematic diagram.Described waistcoat 2 is in splayed；Described waistcoat 2 is provided with the first upper limb perforation 21 and the second upper limb perforation 22；Described first upper limb perforation 21 22 shapes of boring a hole with the second upper limb are consistent, and the first upper limb perforation 21 and the second upper limb are bored a hole and 22 be symmetric；Described waistcoat 2 one end inner surface is provided with sub-VELCRO 25；Described waistcoat 2 other end outer surface is provided with female VELCRO 26；It is bonded to each other that described sub-VELCRO 25 closes female VELCRO 26；Described waistcoat 2 is provided with positive V-arrangement arc section 23 and inverted v-shape arc section 24；Described waistcoat 2 outer surface is additionally provided with signal picker fixing band 27 and signal receiver fixing band 28；Described signal picker fixing band 27 and signal receiver fixing band 28 are Integratively formed with waistcoat 2.
It should be understood that described eeg recording electrode 13 is fixed on the head 11 of laboratory animal 1, signal picker 14 and accepter are then positioned on the waistcoat 2 being worn on laboratory animal 1, volumetric spaces is little, alleviate head 11 pressure of laboratory animal 1, laboratory animal 1 can carry out activity freely, does not affect diet and the water inlet of laboratory animal 1.Additionally, owing to eeg recording electrode 13 is fixed by implantation, therefore mouse head 11 has wound, laboratory animal 1 head 11 of the present invention is only fixed with eeg recording electrode 13, alleviate the pressure that head 11 undertakes, avoid wound to heal, cause laboratory animal 1 to infect even dead, beneficially testing staff's collection to laboratory animal 1.
Described signal picker 14 and signal receiver 15 are each attached on the waistcoat 2 at corresponding laboratory animal 1 back 12, so laboratory animal 1 is in active procedure, the signal picker 14 being fixed on back 12 waistcoat 2 and signal receiver 15 can not be perturbed by its extremity, because laboratory animal 1 is very sensitive, and it is the most flexible, and in prior art, when signal picker 14 and signal receiver 15 are fixed on head 11, owing to laboratory animal 1 is according to self special physiological structure, rear portion extremity can be relied on to perturb signal picker 14 and the signal receiver 15 being fixed on head 11, cause and eeg signal acquisition is brought external interference, cause the failure of animal brain electrical signal collection.
Described waistcoat 2 is provided with the first upper limb perforation 21 and the second upper limb perforation 22, under use state, first upper limb perforation 21 and the second upper limb perforation 22 are respectively used to wear two upper limb of laboratory animal 1, then fixing with female VELCRO 26 laminating by the sub-VELCRO 25 at waistcoat 2 two ends, thus waistcoat 2 is worn in laboratory animal 1, the material preferred elastomeric material of waistcoat 2, so elasticity is adjustable, make waistcoat 2 fixing definite in laboratory animal 1, decrease the external environment interference to EEG signals, the beneficially collection of EEG signals；Waistcoat 2 is provided with positive V-arrangement arc section 23 and inverted v-shape arc section 24, this design is to be designed according to the body structure of laboratory animal 1, position near the throat of laboratory animal 1 it is positioned under positive V-arrangement arc section 23 wearing state, it can be avoided that laboratory animal 1 is strangled to obtain tension, affect breathing and the feed etc. of laboratory animal 1, it is positioned under inverted v-shape arc section 24 wearing state at the abdominal part top position of laboratory animal 1, the abdominal part of laboratory animal 1 can be avoided to be strangled to obtain tension, affect it and digest normally.Described waistcoat 2 outer surface is additionally provided with signal picker fixing band 27 and signal receiver fixing band 28, can be fixed signal picker 14 and signal receiver 15 by fixing band, preferred signals harvester fixing band 27 and signal receiver fixing band 28 are 2.
Embodiment 2
The present embodiment is substantially the same manner as Example 1, and its difference is: refer to another waistcoat 2 outer surface structure schematic diagram that Fig. 5, Fig. 5 are the present invention.Described waistcoat 2 formation outside schematic diagram.Described waistcoat 2 outer surface is additionally provided with signal picker fixed body 29 and signal receiver fixed body 291；Described signal picker fixed body 29 is for fixed signal harvester 14, and described signal receives fixed body for fixed signal receptor 15.
In the present embodiment, by signal picker fixed body 29 and signal receiver fixed body 291, fixed effect is definite, fix signal picker 14 and signal receiver 15 with the employing fixing band in embodiment compared with, be difficult to slip, the interface of each parts is completely embedded.
A kind of Wearable brain electricity laboratory animal 1 harvester of the present invention, volume is little, lightweight, alleviate the pressure of laboratory animal 1 head 11, being conducive to wound healing, testing staff is easy to control, simultaneously during eeg signal acquisition, it is susceptible to external environmental interference, it is possible to for a long time laboratory animal 1 is gathered EEG signals；Only eeg recording electrode 13 is fixed on animal head 11, signal picker 14 is not mounted to animal head 11, is not the most embedded in back part of animal 12 subcutaneous, but is worn on animal with waistcoat 2, the most both reduce the injury to animal and stimulation, and facilitate again testing staff to operate；Signal picker 14 and signal receiver 15 are each attached on the waistcoat 2 at corresponding laboratory animal 1 back 12, and such laboratory animal 1 is in active procedure, and the signal picker 14 being fixed on back 12 waistcoat 2 and signal receiver 15 can not be perturbed by its extremity.Avoid eeg signal acquisition failure；Being provided with waistcoat 2, material preferred elastomeric material, such elasticity is adjustable so that waistcoat 2 is fixing definite in laboratory animal 1, decreases the external environment interference to EEG signals, the beneficially collection of EEG signals；Waistcoat 2 is provided with positive V-arrangement arc section 23, with inverted v-shape arc section 24, this design is to be designed according to the body structure of laboratory animal 1, position near the throat of laboratory animal 1 it is positioned under positive V-arrangement arc section 23 wearing state, it can be avoided that laboratory animal 1 is strangled to obtain tension, affect breathing and the feed etc. of laboratory animal 1, be positioned at the abdominal part top position of laboratory animal 1 under inverted v-shape arc section 24 wearing state, the abdominal part that can avoid laboratory animal 1 is strangled to obtain tension, affects it and digests normally.Described waistcoat 2 outer surface is additionally provided with signal picker fixing band 27 and signal receiver fixing band 28, can be fixed signal picker 14 and signal receiver 15 by fixing band；Being provided with signal picker fixed body 29 and signal receiver fixed body 291, be difficult to slip, the interface of each parts is completely embedded.
The above is only the preferred embodiment of the present invention; it should be pointed out that, for those skilled in the art, on the premise of without departing from the inventive method; can also make some improvement and supplement, these improve and supplement and also should be regarded as protection scope of the present invention.
Claims (10)
1. a wearable laboratory animal brain wave acquisition device, it is characterised in that described brain wave acquisition
Device includes the eeg recording electrode being connected to head, and described eeg recording electrode passes through transmission line and signal
Harvester is set up and is connected；Described signal picker is fixed on the waistcoat that laboratory animal is dressed；Described letter
Number harvester other end is set up with signal receiver and is connected；Described waistcoat is provided with the first upper limb perforation and second
Upper limb is bored a hole；Described waistcoat one end inner surface is provided with sub-VELCRO；Described waistcoat other end outer surface sets
There is female VELCRO；The described female VELCRO of sub-magic laminating is bonded to each other；Described waistcoat is provided with positive V-arrangement
Arc section and inverted v-shape arc section.
Brain wave acquisition device the most according to claim 1, it is characterised in that the first described upper limb is worn
Hole is consistent with the second upper limb perforation shape.
Brain wave acquisition device the most according to claim 1, it is characterised in that the first described upper limb is worn
Hole and the perforation of the second upper limb are symmetric.
Brain wave acquisition device the most according to claim 1, it is characterised in that described waistcoat is splayed.
Brain wave acquisition device the most according to claim 1, it is characterised in that described positive V-arrangement circular arc
The throat position of laboratory animal it is positioned under section wearing state.
Brain wave acquisition device the most according to claim 1, it is characterised in that described inverted v-shape circular arc
It is positioned under section wearing state at the abdominal part top position of laboratory animal.
Brain wave acquisition device the most according to claim 1, it is characterised in that described waistcoat outer surface
It is provided with signal picker fixing band and signal receiver fixing band.
Brain wave acquisition device the most according to claim 7, it is characterised in that described signal picker
Fixing band and signal receiver fixing band are Integratively formed with waistcoat.
Brain wave acquisition device the most according to claim 7, it is characterised in that the material of described waistcoat
Elastomeric material.
Brain wave acquisition device the most according to claim 1, it is characterised in that described waistcoat appearance
Face is additionally provided with signal picker fixed body and signal receiver fixed body.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610361660.1A CN105943033A (en) | 2016-05-26 | 2016-05-26 | A wearable experimental animal electroencephalogram collection device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610361660.1A CN105943033A (en) | 2016-05-26 | 2016-05-26 | A wearable experimental animal electroencephalogram collection device |
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| CN105943033A true CN105943033A (en) | 2016-09-21 |
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| CN201610361660.1A Pending CN105943033A (en) | 2016-05-26 | 2016-05-26 | A wearable experimental animal electroencephalogram collection device |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US11045130B2 (en) | 2017-05-12 | 2021-06-29 | Daegu Gyeongbuk Institute Of Science & Technology | Apparatus for monitoring biosignals of fish while resuscitating the fish at the same time, and method for operating thereof |
| CN114366125A (en) * | 2022-01-27 | 2022-04-19 | 中国人民解放军陆军特色医学中心 | Wearable electroencephalogram system for mammals |
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