CN105929147B - One kind is i.e. with i.e. with toxicity test equipment - Google Patents
One kind is i.e. with i.e. with toxicity test equipment Download PDFInfo
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- CN105929147B CN105929147B CN201610273685.6A CN201610273685A CN105929147B CN 105929147 B CN105929147 B CN 105929147B CN 201610273685 A CN201610273685 A CN 201610273685A CN 105929147 B CN105929147 B CN 105929147B
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
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Abstract
The invention discloses one kind i.e. with i.e. with toxicity test equipment, including test flume, liquid-feeding tube, liquid dispensing device and Water injection tap, liquid dispensing device includes spiral arm, pallet, top is equipped with the water injection container of opening, Agitation Tank, dosing pump and drug reservoir, pallet is arranged on spiral arm end, water injection container is placed on pallet, pallet is equipped with weighing device, spiral arm and a rotating driving device are sequentially connected, at least there are two halts in the surfaces of revolution for pallet, one of halt position is corresponding with Water injection tap, also a halt position is corresponding with Agitation Tank, liquid-feeding tube is connected on Agitation Tank and passes in test flume, dosing pump, rotating driving device and weighing device are electrically connected with a control device.Matching somebody with somebody for the achievable testing liquid of the present invention is used, and provides running water experimental enviroment, overcomes the problems, such as that solvent volatilization causes test solution concentration inaccurate, it is ensured that test accuracy, and high degree of automation, it is easy to operate.
Description
Technical field
The present invention relates to a kind of testing equipment, more specifically, it relates to a kind of i.e. with i.e. with toxicity test equipment.
Background technology
In order to study chemical substance to the toxic effect of aquatile, it is necessary to carry out toxicity contrast test in laboratory.
The basic principle of toxicity contrast test is the advance testing liquid for preparing different experiments concentration, generally sets concentration by log-rank
Group, biological subject are placed in solution, in the case where ensureing that remaining condition is identical, by observing feelings biological in various concentration group
Condition analyzes toxic effect of the chemical substance to aquatile.For volatile substance to be tested, since volatilization causes
Solution concentration changes, and easily result of the test is interfered, therefore generally use continuous-flow type Toxicity test Methods.Continuous-flow type toxicity is tried
Testing needs guarantee test solution constantly to be flowed out from test flume, and has new testing liquid constantly to be supplemented into test flume, to keep
Test solution concentration in test flume.And the volatile property of testing liquid so that the testing liquid for flowing into supplement is preferably existing with existing
With, cause test operation inconvenience, add experiment difficulty.Lack the standard for being exclusively used in continuous-flow type toxicity test in the prior art
Experimental rig, each laboratory can only self manufacture equipment with realize testing liquid i.e. with i.e. use, due to by equipment making equipment
And the factors such as relevant knowledge restrict, and make the operating accuracy of testing equipment by oneself and operation stability is often difficult to reach expected, cause
Time-consuming for experiment, and accuracy is low.The invention of Publication No. CN104196514A disclosed a kind of acidifying on December 10th, 2014
Fracturing fluid is i.e. with i.e. with device, including blending tank, the arrival end of blending tank is parallel with additive unit, thickening agent unit, acid solution
Unit, the port of export are in series with the first centrifugal pump, the first surge tank, the second centrifugal pump, the 3rd pneumatic gate valve, the second surge tank,
Five pneumatic gate valves and excavationg pump；The first pneumatic gate valve is in series between the port of export of acid solution unit and blending tank arrival end；Acid solution
The second pneumatic gate valve is parallel between the port of export of unit and the arrival end of excavationg pump；The port of export and excavationg pump of first surge tank
Arrival end between be parallel with the 4th pneumatic gate valve；Four functional areas are respectively arranged in two surge tanks, are set in functional areas
There are the first blender and snakelike baffle.The arrangement achieves acid solution i.e. with using, the acid solution of preparation without layering, caking phenomenon,
Improve complex acid quality.Meanwhile the device can save unloaded in acidization acid, the link with liquid, improve acidifying correctional effect and
Operating efficiency reduces production cost.The device be production equipment, it is necessary to very big fabricating yard and public work is mating, it is uncomfortable
It shares and is tested equipment.
The content of the invention
Existing toxicity test device is difficult to smoothly be reliably achieved and use matching somebody with somebody for testing liquid, and efficiently and accurately complete
It is easy to operate the present invention provides a kind of high degree of automation to overcome this defect into continuous-flow type toxicity test, experiment knot
Fruit is accurately i.e. with i.e. with toxicity test equipment.
The technical scheme is that：One kind with toxicity test equipment is used, is filled including test flume, liquid-feeding tube, with liquid
It puts and Water injection tap, liquid dispensing device includes spiral arm, pallet, top water injection container, Agitation Tank, dosing pump and drug storage equipped with opening
Container, pallet are arranged on spiral arm end, and water injection container is placed on pallet, and pallet is equipped with weighing device, spiral arm and a rotation driving
Device is sequentially connected, and for pallet at least there are two halt in the surfaces of revolution, one of halt position is corresponding with Water injection tap,
Also a halt position is corresponding with Agitation Tank, and liquid-feeding tube is connected on Agitation Tank and passes in test flume, and dosing pump, rotation are driven
Dynamic device and weighing device are electrically connected with a control device.Under control of the control means, spiral arm can carry water injection container and note
At tap fill water, can be perceived when water reaches predetermined amount by weighing device, at this time spiral arm rotate, by water injection container send to
At Agitation Tank, the water in water injection container is injected in Agitation Tank, while dosing pump startup, preset dose is added in into Agitation Tank
Substance to be tried mixes merga pass liquid-feeding tube with water and flows into test flume, setting dosing pump bolus injection band examination dosages of substance, with regard to energy
The ratio of water is loaded according to the dosage and water injection container, configures the testing liquid for needing concentration.It is continuous by above procedure
Xun Huan, the testing liquid now matched somebody with somebody constantly is injected into test flume, and during experiment, the solution in test flume can as needed outwards
Discharge is consumed for experiment, so as to which the test solution concentration inside guarantee test slot is stablized, and realizes the experimental condition of running water,
So as to meet the requirement of continuous-flow type toxicity test.
Preferably, being fixedly provided with lifting sliding rail on pallet, water funnel, water funnel are slidably connected on lifting sliding rail
It is driven by a lifting cylinder, lifting cylinder is connected on pallet, and in the sliding scale of water funnel, water funnel bottom is always
It stretches into inside water injection container.Water funnel can lift under the driving of lifting cylinder along lifting sliding rail, change height.From note
During tap water receiving, water funnel rises, and bell mouth is close to Water injection tap, with larger water receiving face water receiving, it is ensured that level is really noted
Enter water injection container, while by the drainage and deceleration of water funnel, make the more soft slow entrance water injection container of water, avoid Water injection tap
It directly pours water in higher position into water injection container and causes water impact, cause the splashing of water, so as to avoid water waste and experiment
Contaminated sites；After institute's water receiving amount reaches preset value, water funnel is fallen, and the conical surface of water funnel can cover opening for water injection container
Mouthful, so during next cantilever drives water injection container conversion position, water funnel can not only avoid water filling dragon
Head, moreover it is possible to cover water injection container and water injection container is avoided to escape bottleneck when rocking.
Preferably, the male cone (strobilus masculinus) of water funnel is equipped with gasket, male cone (strobilus masculinus) is pressed in water filling appearance when water funnel declines
In the opening of device.In cantilever rotation process, there are velocity variations when dynamic, stalling is changed, the water in water injection container can rock, water filling leakage
The male cone (strobilus masculinus) of bucket is equipped with gasket, and when such water funnel is fallen, the conical surface of water funnel can tightly cover water injection container
Opening prevents water from escaping bottleneck.
Preferably, the overhanging frame that is slidably connected on lifting sliding rail, the work of be slidably connected end and the lifting cylinder of overhanging frame
Stopper rod connects, and water funnel is fixed on overhanging frame end portion.With this configuration, it can facilitate, be reliably achieved water funnel with rising
Drop slide being slidably connected and being lifted along fixed path.
Preferably, water injection container bottom is equipped with water outlet, water outlet is equipped with electromagnetic water valve, electromagnetic water valve and the control
Device electrical connection processed.Control device switchs electromagnetic water valve by pre-set programs on suitable opportunity, without manually moving water injection container,
It can carry out adding water with liquid even without human attendance, so as to which liquid of matching somebody with somebody that is accurate, continuous, being readily achieved experiment operates.
Preferably, the main body of water injection container be cylindricality, water injection container be equipped with elongated bottleneck, the main body of water injection container with
Elongated bottleneck engaging portion is arranged with a retainer plate, and retainer plate is connected on pallet.The main body of water injection container is combined with elongated bottleneck
There are diameter mutation, retainer plates in portion can easily block water injection container herein, not only forms radial positioning, but also is formed in the axial direction
Unidirectional positioning, can take up water injection container when the water funnel being pressed in water injection container opening being avoided to rise, make water injection container
Position offset influences test accuracy.Water injection container is designed to that the structure that mouthful underbelly is big and bottleneck is elongated is not only convenient for water filling appearance
Device is fixed, and is more conducive to prevent the water in water injection container from rocking effusion.
Preferably, rotating driving device is motor or oscillating cylinder.In this equipment, spiral arm carries water injection container in water filling
Tap, Agitation Tank move back and forth between two positions, and spiral arm is by the rotation of fixed rotation angle, no matter with motor or oscillating cylinder
The function of spiral arm can be more easily realized as rotating driving device.
Preferably, Water injection tap is equipped with Fill control valves, Fill control valves are electrically connected with the control device.Note
Water control valve can rapidly and accurately control water injection time and water from water filling in trend water injection container under control of the control means
Amount.Fill control valves are connected on control device, make Water injection tap by access one controllable system in, preferably with this equipment
In other device cooperations, accurately and accurately tested.
Preferably, the weighing device is pressure sensor.Pressure sensor volume is small, is easily installed on pallet,
Access control apparatus is also easy to, action triggers instruction is provided for other relevant apparatus in this equipment, makes the water injection container of this equipment
The operating procedures energy quick responses such as water filling, water injection container transposition, link up and perform, accurately and accurately tested.
Preferably, this equipment further includes rack, rack is equipped with multilayer mounting bracket, Water injection tap, liquid dispensing device and examination
Check of foundation subsoil is straggly to be arranged on mounting bracket.Rack can provide a mounting platform, and each component, device are become one, are integral
Equipment easily carries out movement, installs.
The beneficial effects of the invention are as follows：
Running water experimental enviroment is provided, guarantee test solution concentration is accurate.The present invention is matched somebody with somebody by the coordination between each component
Close, realize testing liquid i.e. with i.e. with it is without interruption, provide running water experimental enviroment so that this equipment is available for carrying out flowing water
Formula toxicity test overcomes the problems, such as that solvent volatilization causes test solution concentration inaccurate, it is ensured that test accuracy.
High degree of automation, it is easy to operate.The present invention under control of the control means, makes each composition Partial coordination work,
Each action command quick response, each operating procedure link up execution, greatly improve test efficiency, mitigate artificial burden.
Description of the drawings
Fig. 1 is a kind of structure diagram of the present invention；
Fig. 2 is a kind of side structure schematic view of the present invention.
In figure, 1- test flumes, 2- liquid-feeding tubes, 3- spiral arms, 4- pallets, 5- water injection containers, 6- Agitation Tanks, 7- dosing pumps, 8-
Drug reservoir, 9- Water injection taps, 10- rotating driving devices, 11- water funnels, 12- lifting cylinders, 13- lifting sliding rails, 14- hang
Stretch frame, 15- racks, the elongated bottlenecks of 16-, 17- electromagnetic water valves, 18- drain pipes, 19- blenders, 20- dynamic sealing gas distributors,
21- air pressure pumps.
Specific embodiment
The invention will be further described for specific embodiment below in conjunction with the accompanying drawings.
Embodiment 1：
As shown in Figure 1 and Figure 2, it is a kind of i.e. with i.e. with toxicity test equipment, including test flume 1, liquid-feeding tube 2, liquid dispensing device and
Water injection tap 9, liquid dispensing device include the water injection container 5 of spiral arm 3, pallet 4, top equipped with opening, Agitation Tank 6, dosing pump 7, storage
Medicine container 8 and rack 15, rack 15 are equipped with multilayer mounting bracket, and Water injection tap 9, liquid dispensing device and test flume 1 are straggly arranged on not
With on layer mounting bracket, Water injection tap 9 is located at highest point and passes through hose access public water supply pipeline.Spiral arm 3 is in kidney ellipsoid plate
Shape, there are two pallets 4, is respectively arranged on 3 both ends of spiral arm, and water injection container 5 also for two and is respectively placed on two pallets 4, two pallets 4
On be respectively provided with a weighing device, the weighing device be pressure sensor.3 center of spiral arm connects with a rotating driving device 10 transmission
It connects, rotating driving device 5 is the output shaft key connection of motor, spiral arm 3 and the motor.The motor output shaft interrupted output torque,
It pauses after 180 ° every turn, therefore there are two halt, one of halt position and Water injection taps 9 in the surfaces of revolution for pallet 4
Corresponding, another halt position is corresponding with Agitation Tank 6, and liquid-feeding tube 2 is connected on Agitation Tank 6 and passes in test flume 1, dosing pump
7th, rotating driving device 10 and weighing device are electrically connected with a control device, which is microcontroller.Middle part in Agitation Tank 6
A blender 19 is additionally provided with, the abundant mixing of solution in Agitation Tank 6, liquid-feeding tube 2 can be equipped with solenoid valve with 6 junction of Agitation Tank
Door.The main body of water injection container 5 is cylinder, and water injection container 5 is equipped with elongated bottleneck 16, and the opening of water injection container 5 is positioned at elongated
16 top of bottleneck, the main body of water injection container 5 are arranged with retainer plate of the band there are four fixed feet with elongated 16 engaging portion of bottleneck, Gu
Fixed circle is connected in by the bolt on corner on pallet 4, is allowed to take from pallet 4 so as to push down water injection container 5.On pallet 4
Lifting sliding rail 13 is also vertically installed with, water funnel 11 is slidably connected on lifting sliding rail 13, water funnel 11 is by a lifting air
Cylinder 12 drives, and 12 bottom of lifting cylinder is hingedly connected on pallet 4, in the sliding scale of water funnel 11,11 bottom of water funnel
End is stretched into always inside water injection container 5.Be slidably connected an overhanging frame 14 on lifting sliding rail 13, and water funnel 11 is fixed on.Lifting
Slide 13 is made of two parallel cylindrical guide bars, and overhanging frame 14 is T-shaped, including being slidably connected bar and water funnel is fixed
Bar, the bar that is slidably connected form the end that is slidably connected of overhanging frame 14, and the free end of water funnel fixed link is then the another of overhanging frame 14
One end, the bar center that is slidably connected are hinged with the piston rod of lifting cylinder 12, and the bar both ends that are slidably connected are then each via slip ring set
It corresponds and is socketed with two guide rods, water funnel fixed link is vertically welded in the bar center that is slidably connected, and water funnel 11 is logical
Cross the free end that a retainer ring is fixed on water funnel fixed link.The male cone (strobilus masculinus) of water funnel 11 is equipped with sealing made of silica gel
Pad, male cone (strobilus masculinus) is pressed in the opening of water injection container 5 when water funnel 11 declines.5 bottom center of water injection container is equipped with water outlet, phase
Ying Di, 4 center of pallet can hold 5 water outlet of water injection container equipped with through hole and be pierced by.5 water outlet of water injection container is equipped with electromagnetic water valve
17, electromagnetic water valve 17 is electrically connected with the control device.Water injection tap 9 be equipped with Fill control valves, Fill control valves with it is described
Control device electrical connection.One end is vertically arranged a drain pipe 18 in test flume 1, and 18 lower end of drain pipe passes through 1 bottom of test flume.
3 bottom center of spiral arm is equipped with the dynamic sealing gas distributor 20 of an annular, and dynamic sealing gas distributor 20 is looped around rotation with one heart
Outside rotary driving device 10, the tracheae of lifting cylinder 12 is connected on dynamic sealing gas distributor 20.On 15 bottom mounting bracket of rack
Equipped with an air tower, inside there is a small-sized air pressure pump 21, all pneumatic members are supplied with gas by air pressure pump 21 in this equipment, this
Each solenoid valve in equipment gas circuit is also installed in the air tower.
Under control of the control means, spiral arm 3 can carry a wherein water injection container 5 and water is filled at Water injection tap 9, work as water
It can be perceived when reaching predetermined amount by weighing device, Water injection tap 9 stops water filling at this time, while receives spiral arm 3 and rotate, this is noted
Water container 5 is sent to Agitation Tank 6, empty with another water injection container 5 location swap that has drained water of the original place above Agitation Tank 6
Water injection container 5 starts 9 water filling of Water injection tap.The water injection container 5 for reaching 6 top of Agitation Tank opens electricity under control of the control means
Magnetic water valve 17 injects water in Agitation Tank 6 with appropriate flow velocity, while dosing pump 7 starts, and preset dose is added in into Agitation Tank 6
Substance to be tried, setting dosing pump 7 bolus injection band examination dosages of substance just can load water according to the dosage and water injection container 5
Ratio, configure the testing liquid for needing concentration.Substance to be tried device 19 agitated with water mixes after a certain period of time, Agitation Tank 6
On electromagnetic valve open, the testing liquid being made by liquid-feeding tube 2 flow into test flume 1 in, constantly cycled by above procedure,
The testing liquid now matched somebody with somebody constantly is injected into test flume 1, during experiment, liquid level raises and is more than drain pipe 18 in test flume 1
During upper end, extra solution is discharged from drain pipe 18, is consumed for experiment, so as to the test solution concentration inside guarantee test slot 1
Stablize.
Embodiment 2：
Rotating driving device 5 is oscillating cylinder, and the hunting range of oscillating cylinder is 180 °.Remaining is the same as embodiment 1.
Embodiment 3：
Spiral arm 3 is in cross, and pallet 4, water injection container 5 are respectively four, is arranged at four ends of spiral arm 3 correspondingly
Head.The motor is rotated by 90 ° every time of indexing, and there are four halts for each pallet 4.When spiral arm 3 pauses every time, there is one
Water injection container 5 is located at 9 lower section of Water injection tap, and water injection container 5 is located at 6 top of Agitation Tank on the other hand, remaining is filled with the note of water
Water container 5 and the water injection container 5 each one emptied, wait between Water injection tap 9 and Agitation Tank 6 on position.Remaining is the same as real
Apply example 1.
Embodiment 4：
Pallet 4 only there are one, pallet 4 and rotating driving device 10 are located at 3 both ends of spiral arm respectively, and rotating driving device 10 is
One hunting range is 90 ° of oscillating cylinder.Remaining is the same as embodiment 1.
Claims (9)
1. one kind is i.e. with toxicity test equipment is used, including test flume（1）, liquid-feeding tube（2）, liquid dispensing device and Water injection tap（9）,
It is characterized in that liquid dispensing device includes spiral arm（3）, pallet（4）, top be equipped with opening water injection container（5）, Agitation Tank（6）, dosing
Pump（7）And drug reservoir（8）, pallet（4）Arranged on spiral arm（3）End, water injection container（5）It is placed in pallet（4）On, pallet（4）On
Equipped with weighing device, spiral arm（3）With a rotating driving device（10）It is sequentially connected, pallet（4）In the surfaces of revolution at least there are two
Halt, one of halt position and Water injection tap（9）It is corresponding, there are a halt position and Agitation Tank（6）It is corresponding, add
Liquid pipe（2）It is connected to Agitation Tank（6）It goes up and passes to test flume（1）In, dosing pump（7）, rotating driving device（10）With dress of weighing
It puts and is electrically connected with a control device, pallet（4）On be fixedly provided with lifting sliding rail（13）, lifting sliding rail（13）On slidably connect note
Hyponome（11）, water funnel（11）By a lifting cylinder（12）Driving, lifting cylinder（12）It is connected to pallet（4）On, it is noting
Hyponome（11）Sliding scale in, water funnel（11）Water injection container is stretched into bottom always（5）It is internal.
2. it is according to claim 1 i.e. with toxicity test equipment is used, it is characterized in that water funnel（11）Male cone (strobilus masculinus) on
Equipped with gasket, water funnel（11）Male cone (strobilus masculinus) is pressed in water injection container during decline（5）Opening on.
3. it is according to claim 1 i.e. with toxicity test equipment is used, it is characterized in that lifting sliding rail（13）On be slidably connected
One overhanging frame（14）, overhanging frame（14）Be slidably connected end and lifting cylinder（12）Piston rod connection, water funnel（11）Gu
It is scheduled on overhanging frame（14）End.
4. it is according to claim 1 i.e. with toxicity test equipment is used, it is characterized in that water injection container（5）Bottom is equipped with water outlet
Mouthful, water outlet is equipped with electromagnetic water valve, and electromagnetic water valve is electrically connected with the control device.
5. it is according to claim 1 i.e. with toxicity test equipment is used, it is characterized in that water injection container（5）Main body be column
Shape, water injection container（5）It is equipped with elongated bottleneck, water injection container（5）Main body and elongated bottleneck engaging portion be arranged with a retainer plate,
Retainer plate is connected in pallet（4）On.
6. it is according to claim 1 i.e. with toxicity test equipment is used, it is characterized in that rotating driving device（5）For motor or
Oscillating cylinder.
7. it is according to claim 1 i.e. with toxicity test equipment is used, it is characterized in that Water injection tap（9）It is equipped with water filling control
Valve processed, Fill control valves are electrically connected with the control device.
8. it is according to any one of claim 1 to 7 i.e. with toxicity test equipment is used, it is characterized in that the weighing device
For pressure sensor.
9. it is according to any one of claim 1 to 7 i.e. with toxicity test equipment is used, it is characterized in that further including rack
（15）, rack（15）It is equipped with multilayer mounting bracket, Water injection tap（9）, liquid dispensing device and test flume（1）It is straggly to be arranged on mounting bracket
On.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610273685.6A CN105929147B (en) | 2016-04-27 | 2016-04-27 | One kind is i.e. with i.e. with toxicity test equipment |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610273685.6A CN105929147B (en) | 2016-04-27 | 2016-04-27 | One kind is i.e. with i.e. with toxicity test equipment |
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| CN105929147B true CN105929147B (en) | 2018-05-18 |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106442959B (en) * | 2016-10-10 | 2018-09-07 | 环境保护部南京环境科学研究所 | Daphnia magna continuous-flow type toxicity test device |
| CN108392998B (en) * | 2018-05-26 | 2023-11-14 | 维尼健康（深圳）股份有限公司 | Intelligent liquid preparation system |
| CN110643479A (en) * | 2018-06-26 | 2020-01-03 | 深圳市北科生物科技有限公司 | Liquid distribution station |
| CN112526063B (en) * | 2020-10-20 | 2022-06-17 | 浙江省海洋水产研究所 | Device for detecting toxicity of organic matters |
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| CN105929147A (en) | 2016-09-07 |
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