CN105929147A - Ready-to-use toxicity test device - Google Patents
Ready-to-use toxicity test device Download PDFInfo
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- CN105929147A CN105929147A CN201610273685.6A CN201610273685A CN105929147A CN 105929147 A CN105929147 A CN 105929147A CN 201610273685 A CN201610273685 A CN 201610273685A CN 105929147 A CN105929147 A CN 105929147A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
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Abstract
The invention discloses a ready-to-use toxicity test device. The device comprises a test tank, a liquid feeding pipe, a liquid preparation device and a water flooding faucet. The liquid preparation device comprises a rotation arm, a tray, a water flooding container with a top opening, a liquid preparation tank, a dosing pump and a regent storage container. The tray is arranged at the end of the rotation arm. The water flooding container is arranged on the tray. The tray is provided with a weighing device. The rotation arm is transmission-connected to a rotation driving device. The tray in the rotation surface is provided with at least two stopping points. The position of one of the stopping points is corresponding to that of the water flooding faucet and the position of the other one of the stopping points is corresponding to that of the liquid preparation tank. The liquid feeding pipe is connected to the liquid preparation tank and is stretched into the test tank. The dosing pump, the rotation driving device and the weighing device are electrically connected to a controller. The device realizes ready-to-use of a test solution, provides a water test environment, solves the problem of test solution concentration inaccuracy caused by solvent evaporation, ensures test accuracy, has a high automation degree and is convenient for operation.
Description
Technical field
The present invention relates to a kind of testing equipment, more specifically, it relates to one is i.e. joined i.e. uses toxicity test equipment.
Background technology
In order to study chemical substance, hydrobiological toxic effect, needs are carried out toxicity contrast test in laboratory.The ultimate principle of toxicity contrast test is to prepare the testing liquid of different experiments concentration in advance, typically concentration group is set by log-rank, biological subject is placed in solution, in the case of ensureing that remaining condition is identical, by observing situation biological in variable concentrations group, analyze this chemical substance to hydrobiological toxic effect.For volatile material to be tested, owing to volatilization causes solution concentration to change, easily result of the test is interfered, the most generally use continuous-flow type Toxicity test Methods.Continuous-flow type toxicity test needs guarantee test solution constantly to flow out from test flume, and has new testing liquid constantly to supplement in test flume, to keep test solution concentration in test flume.And the volatile character of testing liquid so that flow into the testing liquid supplemented the most now with the current, cause test operation inconvenience, add test difficulty.Prior art lacks the standard assay device being exclusively used in continuous-flow type toxicity test, each laboratory can only i.e. be used to realize i.e. joining of testing liquid by self manufacture equipment, owing to being restricted by factors such as equipment making equipment and relevant knowledges, the operating accuracy of self-control testing equipment and operation stability are often difficult to reach expection, causing testing time-consuming length, accuracy is low.The invention of Publication No. CN104196514A discloses a kind of acidizing and fracturing fluid on the 10th in December in 2014 and i.e. joins i.e. with device, including blending tank, the arrival end of blending tank is parallel with additive unit, thickening agent unit, acid solution unit, and the port of export is in series with the first centrifugal pump, the first surge tank, the second centrifugal pump, the 3rd pneumatic gate valve, the second surge tank, the 5th pneumatic gate valve and excavationg pump；It is in series with the first pneumatic gate valve between the port of export and the blending tank arrival end of acid solution unit；It is parallel with the second pneumatic gate valve between the port of export and the arrival end of excavationg pump of acid solution unit；It is parallel with the 4th pneumatic gate valve between the port of export and the arrival end of excavationg pump of the first surge tank；It is respectively arranged with four functional areas in two surge tanks, in functional areas, is provided with the first agitator and snakelike baffle plate.The arrangement achieves acid solution i.e. joins i.e. use, and the acid solution of preparation, without layering, caking phenomenon, improves complex acid quality.Meanwhile, this device can save in acidization the link unloading acid, dosing, improves acidifying correctional effect and working performance, reduces production cost.This device is production equipment, needs the biggest fabricating yard and public work supporting, is not suitable for use in testing equipment.
Summary of the invention
Existing toxicity test device is difficult to be reliably achieved smoothly i.e. to be used i.e. joining of testing liquid, and complete continuous-flow type toxicity test efficiently and accurately, for overcoming this defect, the invention provides a kind of automaticity high, easy to operate, result of the test is the most i.e. joined and is i.e. used toxicity test equipment.
The technical scheme is that one is i.e. joined and i.e. use toxicity test equipment, including test flume, liquid-feeding tube, liquid dispensing device and Water injection tap, liquid dispensing device includes spiral arm, pallet, top is provided with the water filling container of opening, Agitation Tank, dosing pump and drug reservoir, spiral arm end is located at by pallet, water filling container is placed on pallet, pallet is provided with weighing device, spiral arm and a rotating driving device are in transmission connection, pallet at least two halts in the surfaces of revolution, one of them halt position is corresponding with Water injection tap, also have a halt position corresponding with Agitation Tank, liquid-feeding tube is connected on Agitation Tank and passes in test flume, dosing pump, rotating driving device and weighing device and control device electrical connection.Under control of the control means, spiral arm portability water filling container fills water at Water injection tap, weighing device perception can be passed through when the water yield reaches predetermined amount, now spiral arm rotates, water filling container is delivered at Agitation Tank, water in water filling container is injected in Agitation Tank, dosing pump starts simultaneously, the material to be tried of preset dose is added in Agitation Tank, mix merga pass liquid-feeding tube with water and flow in test flume, set dosing pump bolus injection band examination dosages of substance, just can load the ratio of the water yield according to this dosage and water filling container, configure the testing liquid needing concentration.Constantly circulated by above procedure, the testing liquid that continuous injection is now joined in test flume, in process of the test, solution in test flume can discharge as required, consume for test, thus the test solution concentration within guarantee test groove is stablized, and realize the experimental condition of running water, thus meet the requirement of continuous-flow type toxicity test.
As preferably, pallet is fixedly provided with lifting sliding rail, lifting sliding rail slidably connects water funnel, water funnel is driven by a lift cylinder, lift cylinder is connected on pallet, and in the sliding scale of water funnel, water funnel bottom is stretched into inside water filling container all the time.Water funnel can lift along lifting sliding rail under the driving of lift cylinder, changes height.When from Water injection tap water receiving, water funnel rises, bell mouth is near Water injection tap, with bigger water receiving face water receiving, it is ensured that level really injects water filling container, simultaneously by drain and the deceleration of water funnel, make the more soft slow entrance water filling container of water, avoid Water injection tap directly to pour water in water filling container at higher position and cause water impact, cause the splashing of water, thus avoid water waste and test site to pollute；After institute's water receiving amount reaches preset value, water funnel is fallen, the conical surface of water funnel can cover the opening of water filling container, so during ensuing cantilever drives water filling container dislocation, water funnel is possible not only to avoid Water injection tap, moreover it is possible to capping water filling container avoids water filling container to escape bottleneck because rocking.
As preferably, the male cone (strobilus masculinus) of water funnel is provided with sealing gasket, and when water funnel declines, male cone (strobilus masculinus) is pressed on the opening of water filling container.In cantilever rotation process, there is velocity variations in dynamic, stall, the water in water filling container can rock when changing, the male cone (strobilus masculinus) of water funnel is provided with sealing gasket, when so water funnel is fallen, the conical surface of water funnel can tightly cover the opening of water filling container, prevents water from escaping bottleneck.
As preferably, lifting sliding rail is slidably connected an overhanging frame, and the end that is slidably connected of overhanging frame is connected with the piston rod of lift cylinder, and water funnel is fixed on overhanging frame end portion.By this structure, can facilitate, be reliably achieved the water funnel the being slidably connected path lifting that also edge is fixing with lifting sliding rail.
As preferably, water filling container bottom is provided with outlet, and outlet is provided with electromagnetic water valve, and electromagnetic water valve electrically connects with described control device.Control device and switch electromagnetic water valve by pre-set programs on suitable opportunity, it is not necessary to artificial mobile water filling container, dosing can be carried out even without human attendance and add water, thus accurately, continuously, be readily achieved the dosing operation of test.
As preferably, the main body of water filling container is cylindricality, and water filling container is provided with elongated bottleneck, and the main body of water filling container and elongated bottleneck joint portion are arranged with a ring for fixing, and ring for fixing is connected on pallet.There is diameter sudden change in the main body of water filling container and elongated bottleneck joint portion, ring for fixing can block water filling container easily at this, both radially location had been formed, form unidirectional location the most in the axial direction, avoid the water funnel being pressed in water filling vessel port can take up water filling container when rising, make water filling container that position skew, impact test accuracy to occur.Water filling Vessel Design becomes the little enlarged abdomen of mouth and the elongated structure of bottleneck to be not only convenient for water filling container and fix, and is more conducive to prevent the water in water filling container from rocking effusion.
As preferably, rotating driving device is motor or oscillating cylinder.In this equipment, spiral arm carries water filling container and moves back and forth between Water injection tap, two positions of Agitation Tank, and spiral arm is rotated by the fixing anglec of rotation, no matter can more easily realize the function of spiral arm with motor or oscillating cylinder as rotating driving device.
As preferably, Water injection tap is provided with Fill control valves, and Fill control valves electrically connects with described control device.Fill control valves under control of the control means can water filling in trend water filling container, rapidly and accurately control water injection time and the water yield.Fill control valves is connected to control, on device, to make Water injection tap be access in a controlled system, preferably with other device cooperation in this equipment, efficiently, accurately test.
As preferably, described weighing device is pressure transducer.Pressure transducer volume is little, easily installs on pallet, is also easy to access control apparatus, action triggers instruction is provided for other relevant apparatus in this equipment, the operating procedures such as the water filling container water filling of this equipment, water filling container transposition are made quickly to respond, coherent execution, efficiently, accurately test.
As preferably, this equipment also includes frame, and frame is provided with multilamellar installing rack, and Water injection tap, liquid dispensing device and test flume are straggly to be located on installing rack.Frame can provide a mounting platform, each parts, device is become one, and moves easily as an integral device, installs.
The invention has the beneficial effects as follows:
There is provided running water experimental enviroment, it is ensured that test solution concentration is accurate.The present invention is by the cooperation between each ingredient, realize i.e. using and without interruption i.e. joining of testing liquid, it is provided that running water experimental enviroment so that this equipment can be used for carrying out continuous-flow type toxicity test, solvent volatilization is overcome to cause the inaccurate problem of test solution concentration, it is ensured that test accuracy.
Automaticity is high, easy to operate.The present invention under control of the control means, makes each ingredient co-ordination, and each action command quickly responds, and each operating procedure is coherent to be performed, and is greatly improved test efficiency, alleviates artificial burden.
Accompanying drawing explanation
Fig. 1 is a kind of structural representation of the present invention；
Fig. 2 is a kind of side-looking structural representation of the present invention.
In figure, 1-test flume, 2-liquid-feeding tube, 3-spiral arm, 4-pallet, 5-water filling container, 6-Agitation Tank, 7-dosing pump, 8-drug reservoir, 9-Water injection tap, 10-rotating driving device, 11-water funnel, 12-lift cylinder, 13-lifting sliding rail, 14-overhanging frame, 15-frame, the elongated bottleneck of 16-, 17-electromagnetic water valve, 18-discharging tube, 19-agitator, 20-movable sealing gas distributor, 21-air pressure pump.
Detailed description of the invention
The invention will be further described for specific embodiment below in conjunction with the accompanying drawings.
Embodiment 1:
As shown in Figure 1 and Figure 2, one is i.e. joined and is i.e. used toxicity test equipment, including test flume 1, liquid-feeding tube 2, liquid dispensing device and Water injection tap 9, liquid dispensing device includes that spiral arm 3, pallet 4, top are provided with the water filling container 5 of opening, Agitation Tank 6, dosing pump 7, drug reservoir 8 and frame 15, frame 15 is provided with multilamellar installing rack, Water injection tap 9, liquid dispensing device and test flume 1 are straggly to be located on different layers installing rack, and Water injection tap 9 is positioned at highest point and accesses public water supply pipeline by a flexible pipe.Spiral arm 3 is in kidney ellipsoid tabular, and pallet 4 has two, is respectively arranged on spiral arm 3 two ends, and water filling container 5 is also two and is respectively placed on two pallets 4, and two pallets 4 are respectively provided with a weighing device, and this weighing device is pressure transducer.Spiral arm 3 central authorities are in transmission connection with a rotating driving device 10, and rotating driving device 5 is motor, and spiral arm 3 is bonded with the output shaft of this motor.This motor output shaft interrupted output torque, pause after 180 ° every turn, therefore pallet 4 has two halts in the surfaces of revolution, one of them halt position is corresponding with Water injection tap 9, another halt position is corresponding with Agitation Tank 6, liquid-feeding tube 2 is connected on Agitation Tank 6 and passes in test flume 1, and dosing pump 7, rotating driving device 10 and weighing device and one control device electrical connection, and this control device is single-chip microcomputer.In Agitation Tank 6, middle part is additionally provided with an agitator 19, can fully be mixed by solution in Agitation Tank 6, and liquid-feeding tube 2 and Agitation Tank 6 junction are provided with electromagnetic valve.The main body of water filling container 5 is cylindrical, water filling container 5 is provided with elongated bottleneck 16, the opening of water filling container 5 is positioned at elongated bottleneck 16 top, the main body of water filling container 5 and elongated bottleneck 16 joint portion are arranged with one with the ring for fixing of four fixing feet, ring for fixing is connected on pallet 4 by the bolt on corner, thus pushes down water filling container 5 and be allowed to take from pallet 4.Lifting sliding rail 13 the most vertically it is installed with on pallet 4, water funnel 11 is slidably connected on lifting sliding rail 13, water funnel 11 is driven by a lift cylinder 12, lift cylinder 12 bottom is hinged to be connected on pallet 4, in the sliding scale of water funnel 11, it is internal that water funnel 11 bottom stretches into water filling container 5 all the time.Be slidably connected on lifting sliding rail 13 an overhanging frame 14, and water funnel 11 is fixed on.Lifting sliding rail 13 is made up of two parallel cylindrical guide bars, overhanging frame 14 is T-shaped, including being slidably connected bar and water funnel fixes bar, the bar that is slidably connected constitutes the end that is slidably connected of overhanging frame 14, water funnel fixes the free end of bar then for the other end of overhanging frame 14, the bar that is slidably connected is central hinged with the piston rod of lift cylinder 12, be slidably connected bar two ends then each via slip ring set and two guide post one_to_one corresponding sockets, water funnel is fixed bar and is vertically welded in the bar central authorities that are slidably connected, water funnel 11 is fixed on water funnel by a retainer ring and fixes the free end of bar.The male cone (strobilus masculinus) of water funnel 11 is provided with the sealing gasket that silica gel is made, and when water funnel 11 declines, male cone (strobilus masculinus) is pressed on the opening of water filling container 5.Water filling container 5 bottom center is provided with outlet, and correspondingly, pallet 4 center is provided with through hole and can hold water filling container 5 outlet and pass.Water filling container 5 outlet is provided with electromagnetic water valve 17, and electromagnetic water valve 17 electrically connects with described control device.Water injection tap 9 is provided with Fill control valves, and Fill control valves electrically connects with described control device.In test flume 1, one end is vertically arranged a discharging tube 18, and discharging tube 18 lower end passes bottom test flume 1.Spiral arm 3 bottom center is provided with the movable sealing gas distributor 20 of an annular, and movable sealing gas distributor 20 concentric ring is wound on outside rotating driving device 10, and the trachea of lift cylinder 12 is connected on movable sealing gas distributor 20.Frame 15 bottom installing rack is provided with an air tower, inside has a small-sized air pressure pump 21, and being supplied by air pressure pump 21 with gas of all pneumatic members on this equipment, each electromagnetic valve in this equipment gas circuit is also installed in this air tower.
Under control of the control means, a spiral arm 3 portability wherein water filling container 5 fills water at Water injection tap 9, weighing device perception can be passed through when the water yield reaches predetermined amount, now Water injection tap 9 stops water filling, accept spiral arm 3 to rotate simultaneously, delivering at Agitation Tank 6 by this water filling container 5, with water filling container 5 location swap that another above Agitation Tank 6 of original place has drained water, empty water filling container 5 starts Water injection tap 9 water filling.Arrive the water filling container 5 above Agitation Tank 6 and open electromagnetic water valve 17 under control of the control means, water is injected in Agitation Tank 6 with suitable flow velocity, dosing pump 7 starts simultaneously, the material to be tried of preset dose is added in Agitation Tank 6, set dosing pump 7 bolus injection band examination dosages of substance, just can load the ratio of the water yield according to this dosage and water filling container 5, configure the testing liquid needing concentration.After examination material device agitated with water 19 mixes certain time, electromagnetic valve on Agitation Tank 6 is opened, the testing liquid being made into flows in test flume 1 by liquid-feeding tube 2, constantly being circulated by above procedure, the testing liquid that continuous injection is now joined in test flume 1, in process of the test, when in test flume 1, liquid level raises and exceedes discharging tube 18 upper end, unnecessary solution is discharged from discharging tube 18, consumes for test, thus the test solution concentration within guarantee test groove 1 is stable.
Embodiment 2:
Rotating driving device 5 is oscillating cylinder, and the hunting range of oscillating cylinder is 180 °.Remaining is with embodiment 1.
Embodiment 3:
Spiral arm 3 is in cross, and pallet 4, water filling container 5 are respectively four, is arranged at four terminations of spiral arm 3 correspondingly.Described motor is rotated by the indexing of each 90 °, and each pallet 4 all has four halts.When spiral arm 3 pauses every time, a water filling container 5 is had to be positioned at below Water injection tap 9, water filling container 5 is positioned at above Agitation Tank 6 on the other hand, remaining water filling container 5 being filled with water and the water filling container 5 each emptied, and is between Water injection tap 9 and Agitation Tank 6 and waits on position.Remaining is with embodiment 1.
Embodiment 4:
Pallet 4 only has one, and pallet 4 and rotating driving device 10 lay respectively at spiral arm 3 two ends, rotating driving device 10 be a hunting range be the oscillating cylinder of 90 °.Remaining is with embodiment 1.
Claims (10)
- null1. i.e. join and i.e. use toxicity test equipment for one kind，Including test flume (1)、Liquid-feeding tube (2)、Liquid dispensing device and Water injection tap (9)，It is characterized in that liquid dispensing device includes spiral arm (3)、Pallet (4)、Top is provided with the water filling container (5) of opening、Agitation Tank (6)、Dosing pump (7) and drug reservoir (8)，Spiral arm (3) end is located at by pallet (4)，Water filling container (5) is placed on pallet (4)，Pallet (4) is provided with weighing device，Spiral arm (3) is in transmission connection with a rotating driving device (10)，Pallet (4) at least two halts in the surfaces of revolution，One of them halt position is corresponding with Water injection tap (9)，Also have a halt position corresponding with Agitation Tank (6)，Liquid-feeding tube (2) is connected to Agitation Tank (6) and above and passes in test flume (1)，Dosing pump (7)、Rotating driving device (10) and weighing device and control device electrical connection.
- The most according to claim 1 i.e. joining i.e. uses toxicity test equipment, it is characterized in that being fixedly provided with on pallet (4) lifting sliding rail (13), water funnel (11) is slidably connected on lifting sliding rail (13), water funnel (11) is driven by a lift cylinder (12), lift cylinder (12) is connected on pallet (4), in the sliding scale of water funnel (11), it is internal that water funnel (11) bottom stretches into water filling container (5) all the time.
- The most according to claim 2 i.e. joining i.e. uses toxicity test equipment, it is characterized in that the male cone (strobilus masculinus) of water funnel (11) is provided with sealing gasket, and when water funnel (11) declines, male cone (strobilus masculinus) is pressed on the opening of water filling container (5).
- The most according to claim 2 i.e. joining i.e. uses toxicity test equipment, it is characterized in that the overhanging frame (14) that is slidably connected on lifting sliding rail (13), the end that is slidably connected of overhanging frame (14) is connected with the piston rod of lift cylinder (12), and water funnel (11) is fixed on overhanging frame (14) end.
- The most according to claim 1 i.e. joining i.e. uses toxicity test equipment, it is characterized in that water filling container (5) bottom is provided with outlet, and outlet is provided with electromagnetic water valve, and electromagnetic water valve electrically connects with described control device.
- The most according to claim 1 i.e. joining i.e. uses toxicity test equipment, the main body that it is characterized in that water filling container (5) is cylindricality, water filling container (5) is provided with elongated bottleneck, and the main body of water filling container (5) and elongated bottleneck joint portion are arranged with a ring for fixing, and ring for fixing is connected on pallet (4).
- The most according to claim 1 i.e. joining i.e. uses toxicity test equipment, it is characterized in that rotating driving device (5) is motor or oscillating cylinder.
- The most according to claim 1 i.e. joining i.e. uses toxicity test equipment, it is characterized in that Water injection tap (9) is provided with Fill control valves, and Fill control valves electrically connects with described control device.
- The most according to any one of claim 1 to 8 i.e. joining i.e. uses toxicity test equipment, it is characterized in that described weighing device is pressure transducer.
- The most according to any one of claim 1 to 8 i.e. joining i.e. uses toxicity test equipment, it is characterized in that also including frame (15), and frame (15) is provided with multilamellar installing rack, Water injection tap (9), liquid dispensing device and test flume (1) is straggly is located on installing rack.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610273685.6A CN105929147B (en) | 2016-04-27 | 2016-04-27 | One kind is i.e. with i.e. with toxicity test equipment |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610273685.6A CN105929147B (en) | 2016-04-27 | 2016-04-27 | One kind is i.e. with i.e. with toxicity test equipment |
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| CN105929147A true CN105929147A (en) | 2016-09-07 |
| CN105929147B CN105929147B (en) | 2018-05-18 |
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| CN112526063A (en) * | 2020-10-20 | 2021-03-19 | 浙江省海洋水产研究所 | Device for detecting toxicity of organic matters |
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| CN108392998B (en) * | 2018-05-26 | 2023-11-14 | 维尼健康（深圳）股份有限公司 | Intelligent liquid preparation system |
| CN110643479A (en) * | 2018-06-26 | 2020-01-03 | 深圳市北科生物科技有限公司 | Liquid distribution station |
| CN112526063A (en) * | 2020-10-20 | 2021-03-19 | 浙江省海洋水产研究所 | Device for detecting toxicity of organic matters |
| CN112526063B (en) * | 2020-10-20 | 2022-06-17 | 浙江省海洋水产研究所 | Device for detecting toxicity of organic matters |
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| CN105929147B (en) | 2018-05-18 |
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