CN105919913A - Skin care composition and paste-form firming cream prepared from skin care composition - Google Patents

Skin care composition and paste-form firming cream prepared from skin care composition Download PDF

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CN105919913A
CN105919913A CN201610304119.7A CN201610304119A CN105919913A CN 105919913 A CN105919913 A CN 105919913A CN 201610304119 A CN201610304119 A CN 201610304119A CN 105919913 A CN105919913 A CN 105919913A
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acid
ester
skin care
skin
extract
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CN105919913B (en
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段慧珍
萧贺左
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Zhao Xianliang
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A61K8/988Honey; Royal jelly, Propolis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
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  • Cosmetics (AREA)

Abstract

The invention provides a skin care composition, which consists of the following materials inparts by weight: 0.03-0.05 parts of hydrolyzed protein, 0.2-0.5 parts of glucan, 0.1-0.3 parts of trehalose, 0.1-0.2 parts of radix puerariae and wild yam extracts, 0.1-0.3 parts of evening primrose oil, 0.1-0.3 parts of borage oil, 0.05-0.1 parts of a royal jelly extract and 0.1-0.2 parts of a flos rosae rugosae extract. The invention also provides an application of the skin care composition in producing cosmetics. The invention also provides a cosmetic, which comprises the skin care composition. The invention also provides a method for preparing a paste-form firming cream.

Description

A kind of skin care compositions and paste prepared therefrom compact frost
Technical field
The present invention relates to cosmetic field, compact frost particularly to a kind of skin care compositions and paste prepared therefrom.
Background technology
Skin aging is a kind of lasting gradual physiological process, directly affects outward appearance and the function of skin.Wrinkle is then A kind of mark of skin aging performance, is referred to as " annual ring of life ".Along with the raising of people's quality of life, anti-aging compact Skin removed wrinkle, returns to the topic that the youth become consumers in general to pay close attention to.In recent years, natural physiological active material is used to improve Because of lax, skin occurs that the anti-aging anti-wrinkle cosmetic that compacts of wrinkle is increasingly valued by the people, its safety and both effectiveness The most naturally consumer is become and emphasis that producer is paid close attention to.
Skin aging is in addition to the factor that its body aged skin cells is bred, metabolism slows down, and the impact of environmental factors is also The biggest.Skin is the natural cover for defense resisting external environment infringement.But it is exposed to the external environment for a long time, inevitably it is subject to To damage, the most nocuous factor is ultraviolet, infrared ray, pollution and flue dust.When skin is exposed to external environment, carefully Born of the same parents can be constantly be generated free radical, these free radicals can injure epidermis and corium (damage of oxidisability include oil peroxidation and Weaken skin defense function), cause premature skin ageing (skin wrinkle occurs and becomes lax), be exposed to sun for a long time The position that light and reaction reduce.Ultraviolet radiation can make free-radical contents in skin increase, and also can cause elastin laminin and collagen Degraded so that skin is roughening, lacks flexibility, lax, form wrinkle.
Skin aging is generally embodied in skin elasticity, wrinkle of skin and roughness, moistens the several respects such as intensity.Daily life In simple use moisturizer skin protection prevention skin aging is clearly inadequate.The factors such as environment, sunlight and pressure can make Obtain free radical and greatly injure skin, promote skin ageing to accelerate.
Chinese patent CN102834088A provides cosmetics base material and the cosmetics containing this cosmetics base material;China Patent CN1313073C provides the topical dermatological and/or hair composition comprising aminosal;Chinese patent CN105188660A provides cosmetic composition;Chinese patent CN101816620B provides a kind of skin-lightening cosmetic and system thereof Preparation Method and application.
Present inventor finds that during completing the present invention hydrolyzed protein and glucosan have looks improving and the skin nourishing Effect, but simultaneously in the presence of can easily produce variable color and go bad, stability declines, and has influence on effect of skin protection, particularly affects Effect of firm skin.
Summary of the invention
For prior art problem, the first aspect of the invention provides a kind of skin care compositions, in parts by weight, by water Solve albumen 0.03-0.05 part, glucosan 0.2-0.5 part, trehalose 0.1-0.3 part, Radix Puerariae and Rhizoma Dioscoreae root extract 0.1-0.2 Part, Radix Oenotherae erythrosepalae oil 0.1-0.3 part, borage oil 0.1-0.3 part, Lac regis apis extract 0.05-0.1 part, rose extract 0.1- 0.2 part of composition.
In some embodiments, the mean molecule quantity of described hydrolyzed protein is 5000-15000Da, described hydrolyzed protein In containing the acidic amino acid of 20 weight %-50 weight %.
In some embodiments, the extracting method of described Radix Puerariae and Rhizoma Dioscoreae root extract is, Radix Puerariae and Rhizoma Dioscoreae root is washed Only, pulverize last by Radix Puerariae and weight ratio 1:(0.5-2 of Rhizoma Dioscoreae root) mix homogeneously, use alcohol reflux 2-3h, carry Taking 3-4 time, cold preservation 10-15h, filter, filtrate, through being evaporated to without ethanol, to obtain final product.
In some embodiments, the extracting method of described rose extract is, weighs Flos Rosae Rugosae powder, adds ethanol, leaching Using extracting through microwave heating 2-3 time after bubble 2-3h, filter, filtrate, through being evaporated to without ethanol, to obtain final product.
The second aspect of the invention provides the application in producing cosmetics of a kind of skin care compositions as above.
The third aspect of the invention provides a kind of cosmetics, wherein contains skin care compositions as above.
In some embodiments, the skin care compositions described above weight content in these cosmetics is 0.5%-20%.
In some embodiments, cosmetics as above, it compacts frost for paste.
In some embodiments, paste as above a kind of compacts frost, wherein, containing above-mentioned skin care compositions, Oil-soluble ingredients, emulsifying agent, polyhydric alcohol, thickening agent, pH adjusting agent, water.
The fourth aspect of the invention provide a kind of prepare a kind of paste as above compact frost method, including following Step:
(1) adding oil-soluble ingredients, emulsifying agent, Radix Oenotherae erythrosepalae oil, borage oil, be heated to 80-90 DEG C, dissolve completely, stirring is all As A phase after even.
(2) by pH adjusting agent water dissolution, standby as B phase.
(3) add thickening agent, water, until completely dissolved, add polyhydric alcohol, glucosan, trehalose, be heated to 80-90 DEG C, Dissolve completely, as C phase after stirring.
(4) A is added to C phase, vacuum homogenizing 3-10min, start cooling.
(5) treat that temperature is down to 40-50 DEG C, add Radix Puerariae and Rhizoma Dioscoreae root extract, hydrolyzed protein, Lac regis apis extract, rose Rare extract, is stirring evenly and then adding into B phase, stirs, cooling.
(6) treat that temperature is down to 30-40 DEG C, discharging, to obtain final product.
The present invention uses specific Radix Puerariae and the extracting method of Rhizoma Dioscoreae root extract, improves stablizing of skin care compositions Property, make hydrolyzed protein and glucosan will not produce variable color denaturalization phenomenon in the presence of simultaneously, also further increase skin care compositions The effect of firm skin.
Detailed description of the invention
Unless otherwise defined, all technology used herein and scientific terminology have skill common with art of the present invention The identical implication that art personnel are generally understood that.When there is contradiction, it is as the criterion with the definition in this specification.
" quality, concentration, temperature, time or other value or parameter are preferred with scope, preferred scope or a series of upper limit During the Range Representation that value and lower preferable values limit, this is appreciated that and specifically discloses by any range limit or preferred value All scopes that arbitrary pairing with any range lower limit or preferred value is formed, regardless of whether whether this scope separately discloses. Such as, the scope of 1-50 be understood to include selected from 1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18, 19、20、21、22、23、24、25、26、27、28、29、30、31、32、33、34、35、36、37、38、39、40、41、42、43、 44, any numeral, number combinatorics on words or the subrange and all between above-mentioned integer of 45,46,47,48,49 or 50 Fractional value, such as, 1.1,1.2,1.3,1.4,1.5,1.6,1.7,1.8 and 1.9.About subrange, specifically consider from scope Interior any end points starts " the nested subrange " extended.Such as, the nested subrange of exemplary range 1-50 can include 1-10,1-20,1-30 and 1-40 on one direction, or 50-40,50-30,50-20 and the 50-10 on other direction.”
The first aspect of the invention provides a kind of skin care compositions, in parts by weight, by hydrolyzed protein 0.03-0.05 part, Portugal Polysaccharide 0.2-0.5 part, trehalose 0.1-0.3 part, Radix Puerariae and Rhizoma Dioscoreae root extract 0.1-0.2 part, Radix Oenotherae erythrosepalae oil 0.1-0.3 part, Borage oil 0.1-0.3 part, Lac regis apis extract 0.05-0.1 part, rose extract 0.1-0.2 part composition.
Hydrolyzed protein
Term " hydrolyzed protein " refers to the protein hydrolysate obtained by being hydrolyzed protein.Including homogenizing or Heterogeneous proteins or the hydrolyzate of its each component, derivant or its mixture.Described hydrolyzed protein, by with acid, alkali, Enzyme or combinations thereof use and are obtained by partial proteolysis, as its protein source, can enumerate animal protein, Vegetable protein, it is derived from the protein etc. of microorganism.As animal protein, such as, can enumerate collagen and (also include making Collagen for its modifier), keratin, fibroin, sericin, casein, conchiolin, elastin laminin, protamine, chicken Deng egg yolk protein, albumen protein;As vegetable protein, such as, can enumerate Semen sojae atricolor, Semen Tritici aestivi, rice (Testa oryzae), sesame The protein that fiber crops, Semen Pisi sativi, Semen Maydis, potato class etc. are contained;As being derived from the protein of microorganism, such as, can enumerate from referred to as yeast Pseudomonas, Candida, the yeast of plan Endosporus, beer yeast, saccharomyces sake yeast in separate yeast protein, The protein separated from Mycophyta (basidiomycetes), chlorella, the hydrolysis of protein spirulina etc. being derived from Sargassum.
Hydrolyzed protein of the present invention, except industrial acquisition easy degree, coordinate in cosmetics time peace Outside the height of full property, if the impact on skin-tightening degree when considering to act on skin, preferably phytoprotein hydrolysis Thing, keratin hydrolyzate, casein hydrolysate, wherein, particularly preferred phytoprotein hydrolysate.
The method being prepared hydrolyzed protein by above-mentioned protein source includes, but are not limited to 1) acid hydrolysis;2) basic hydrolysis;With 3) use Suitably protease carries out enzyme hydrolysis.These and other some method preparing hydrolyzed protein is well-known in the art 's.It addition, the hydrolyzed protein being applicable to the present composition is also commercially available.
Character and/or the hydrolysis degree of the mean molecule quantity general opsin matter of hydrolyzed protein are about 2 hundred to hundreds of thousands roads Er Dun.Although the hydrolyzed protein of low-molecular-weight is conducive to absorbing, but storage effect is poor, apt to deteriorate.On the contrary, very high molecular The permeability of protein be not fine, in general, in the present invention, the suitable mean molecule quantity of hydrolyzed protein used is 50000 Dalton or less.
Some preferred embodiment in, the mean molecule quantity of described hydrolyzed protein is 5000-15000Da.
Each protein molecule is regarded as amino acid whose polymer.Existing 20 kinds of natural amino acids.Each have with The shared skeleton that 20 kinds of variable side chains connect.Aminoacid is divided into neutrality, basic amino acid, acid generally according to the electric charge of variable side chain Acidic amino acid.
Belong to acidic amino acid has aspartic acid and glutamic acid.Both aminoacid is at the variable side chain of each of which End has a carboxyl.
Belong to basic amino acid has lysine, arginine and histidine.All these aminoacid in each of which can Become in side chain containing amino.
Relative to basic amino acid, the protein that acidic amino acid occupies the majority may carry in the range of the pH that cosmetics are commonly used Negative charge.On the contrary, the protein containing more basic amino acid may be positively charged under condition of similarity.
In some embodiments, described hydrolyzed protein contains the acidic amino acid of 20 weight %-50 weight %.
Total amino acids composition according to hydrolyzed protein or hydrolyzed protein mixture, easily calculates acidic amino acid in hydrolysis Percentage by weight in albumen.These compositions are the most commonly known.Or ordinary skill people in available this area The aminoacid composition of the known commercial measurement protein of member.These technology include, but are not limited to (1) automatization amino acid analysis and (2) high pressure liquid chromatography.These technology separate each aminoacid, and can measure the percentage by weight of acidic amino acid.
In some embodiments, the mean molecule quantity of described hydrolyzed protein is 5000-15000Da, described hydrolyzed protein In containing the acidic amino acid of 20 weight %-50 weight %.
Some preferred embodiment in, the mean molecule quantity of described hydrolyzed protein is 5000-15000Da, described water Solve the acidic amino acid containing 30 weight %-40 weight % in albumen.
In the skin care compositions that the present invention provides, in parts by weight, containing hydrolyzed protein 0.03-0.05 part.
Glucosan
Glucosan, also known as dextran.For a kind of polysaccharide.It is present in the mucus that certain micro-organisms is secreted in growth course. Glucosan has higher molecular weight, and mainly by D-glucopyanosyl with α, 1 → 6 is bonded, and side chain point has 1 → 2,1 → 3,1 → 4 connections.Along with microbe species and the difference of growth conditions, its structure also has difference.
Glucosan is with beta glucan most physiologically active.The poly that beta glucan active structure is made up of glucose unit Sugar, they great majority are by β-1, and 3 combine, and this is Fructus Vitis viniferae sugar chain connected mode.It can activated macrophage and neutrophilia Leukocytes etc., therefore can improve leukin, the basic element of cell division and distinct antibodies content, stimulate body immune system comprehensively.That , body just has more being ready to resist the disease that microorganism causes.It is thin that beta glucan can make injured body lymphocyte produce The ability of intracellular cytokine (IL-1) recovers rapidly normal, effectively regulates human body immune function.Great many of experiments shows, beta glucan can promote Enter internal IgM antibody to produce, to improve humoral immunization ability.This glucosan activating cell can excite the non-specific defence of host Mechanism, therefore apply and deeply attract attention in terms for the treatment of wound in tumor, infection disease.Through specific step extraction and without endotoxin β-1, 3-glucosan has assert it is the material of kind of safety at U.S. FDA, can make an addition to normal food, and many report display mouse are administered orally ferment Female β-1,3-glucosan, the antibacterial phagocytosis of strong peritoneal cell can be increased.
Glucosan can stimulate Skin Cell activity, strengthens the immunity protection function of skin self, efficient repairing sheath skin, reduces Wrinkle of skin produces, delay skin aging, but inventor finds easily to become when glucosan and hydrolyzed protein coexist under study for action Complexion changed matter, affects the stability of skin care compositions, makes the function of firm skin reduce.
In the skin care compositions that the present invention provides, in parts by weight, containing glucosan 0.2-0.5 part.
Trehalose
Term " trehalose " is with 1 by two glucose molecules, the nonreducing sugar that 1-glycosidic bond is constituted, and has 3 kinds of isomers i.e. Trehalose (α, α), isotrehalose (β, β) and neotrehalose (α, β), and various bioactivators is had non-specific protection Effect, is a kind of safe and reliable natural saccharide.Trehalose in nature in many edible animals and plants and microbial body all It is widely present, such as mushroom class, seaweeds, beans, shrimp, bread, medicated beer and culture propagation food edible in people's daily life In have the trehalose that content is higher.
Trehalose has the protective effect of mystery to organism, is because trehalose and at high temperature, high and cold, hyperosmosis and does The protecting film of uniqueness, protected protein matter molecule invariance effectively can be formed at cell surface under the severe environmental conditions such as dry dehydration Inactivation, thus the life process of the body that sustains life and biological characteristic.Many adverse circumstances to external world show outstanding degeneration-resistant tolerance , all internal substantial amounts of trehalose there is and has direct relation in the species of power with them.And in nature as sucrose, glucose etc. its Its saccharide, does not the most possess this function.The functional characteristic of this uniqueness so that trehalose except can as pharmaceutical grade protein, Beyond the excellent activity protective agent of enzyme, vaccine and other biological goods, be also to maintain cytoactive, moisturizing class cosmetics important Composition.
Trehalose application on cosmetics is the holding cell viability having excellence based on it and biomacromolecule activity Characteristic.Skin Cell, especially epidermis cell, under the environment such as high temperature, high and cold, dry, intensive ultraviolet radiation, easily lose Moisture generation keratinization, even death come off and make skin damage.Trehalose can form one at cell surface layer in this case The protecting film that layer is special, the mucus separated out from film is not only moistened Skin Cell, is also had and radiate by external heat Function, thus protect the skin will not be impaired.Substantial amounts of research with practice have shown that, trehalose can protect epidermis cell film effectively Structure, activating cell, nurse one's health skin, make skin health natural, flexible.Epidermis cell is in high temperature, ultraviolet high and cold, dry, strong Under the environment such as beta radiation, easily drying out and make skin damage, trehalose can be formed at cell surface layer in this case One layer of special protecting film, keeps the original nutrition of skin and moisture, it is to avoid skin sunburn and melanin deposition, is effective against skin Catabiosis;The mucus separated out from film can gentle Glycerin, make that skin jade-like stone is bright, gloss, tender.
In the skin care compositions that the present invention provides, in parts by weight, containing trehalose 0.1-0.3 part.
Radix Puerariae and Rhizoma Dioscoreae root extract
Radix Puerariae, for the dry root of legume pueraria lobata.Cool in nature, sweet in the mouth, pungent, attach to the lung and stomach meridians.There is expelling pathogenic factors from muscles for reducing heat, rash, promote the production of body fluid Quench the thirst, effect of yang invigorating antidiarrheal.Compendium of Material Medica is recorded: " ten doses of clouds of book on Chinese herbal medicine, expelling the excess with mild diaphoretic, Herba Ephedrae, the genus of Radix Puerariae.Lid Herba Ephedrae Be Taiyang channel medicine, double enter lung meridian, lung governing skin and hair;Radix Puerariae is Yangming Channel medicine, double enter spleen channel, spleen governing muscles.So two taste medicines are the lightest Raise and dissipate, and entered far different also." " Bencao Jingshu " record: " Radix Puerariae, dismisses the positive bright main medicine of epidemic febrile disease pathogenic heat also, therefore master disappears Yearningly, high fever of the body, heat is stopped up chest and diaphragm and is vomitted.Dissipating and rise, the property of wind medicine also, therefore leads all numbness." " cold headache is held concurrently stiffness of the nape pain along the spinal column, And bone pain person all over, it is bright that heresy does not still enter sun to the foot sun yet, therefore without thirsty card, should not take." " book on Chinese herbal medicine converges and says " record: " Radix Puerariae, fresh breeze Cold, clean pathogenic factor in the exterior, expelling pathogenic factors from muscles heat, only excessive thirst.Rush down the medicine of stomach-fire also.Tasting sight and deliver the medicine dissipating heresy, its product are the most, as Herba Ephedrae pulls out sun battalion / cold, the wind that Ramulus Cinnamomi Xie Taiyangwei divides, Radix Saposhnikoviae, Folium Perillae dissipate the sun wind and cold at table, and it is cold at table that Rhizoma Ligustici, Rhizoma Et Radix Notopterygii dissipate the sun Wet, all claim to dissipate medicine also, and dissipating of Radix Puerariae, also enter the sun, also dispersing wind and cold, different again, if non-numb, osmanthus, revive, anti-, Xin Xiang Warm-dryness syndrome, dissipates and damages the mistake of middle gas also;If non-Rhizoma Ligustici, Rhizoma Et Radix Notopterygii, dissipate and have the anxiety of consumption nutrient blood also." " legendary god of farming's book on Chinese herbal medicine Warp " record: " quench one's thirst, high fever of the body, vomiting, all numbness, plays cloudy gas, solves all poison." " Mingyi Bielu " record: " excessive cold invading middle-JIAO(the spleen and stomach) wind headache of curing the wound, Expelling pathogenic factors from muscles delivers perspiration, loosing the interspaces of skin and muscles, treats incised wound, only side of body wind pain.”
The main chemical composition of Radix Puerariae is flavone compound, volatile oil compound, saponins compound, aminoacid, biology Alkali, phytosterin compound etc., wherein flavonoid content is most.
Flavonoid: based on isoflavone, other for tectorigenin, irisolidon, formononetin, Glycitein, Daidezin, Quercetin, genistein, acacetin, iridin, kakkalide, glycitin, nicotiflorin, sissoo glycosides, olecranon Legumin first, 6 "-O-xylose iridin, 6 "-O-xylose daidzin.
Volatile oil: n-docosane, thujopsene, Trans-caryophyllene, oxalene, hexadecylic acid, aldehyde C-9, the joyous base of hexahydro alloy third Ketone, 2,6-diisobutyl paracresol, acetic acid terpin fat, methyl palmitate, dibutyl phthalate, Camphora.
Saponins: soybean saponin I, soybean saponin A b, soybean saponin β g, kaikasaponin I, kaikasaponin III, glycyrrhizin.
Other: cupreol-3-O-β-D-Glucose glycosides, cupreol, N-caproyl-N1-glucose-tryptophan, stone Wax, p-coumaric acid, stigmasterol glycosides, daucosterol, trace element, protein, polysaccharide.
Rhizoma Dioscoreae root is the dry rhizome for Dioscoreaceae plant Rhizoma Dioscoreae DioscoreaoppositaThunb..Property flat, sweet in the mouth. There is strengthening the spleen and stomach, effect that lung benefiting kidney, qi-restoratives are won.Cure mainly anorexia and loose stool, asthenia, breath with cough, frequent micturition, leukorrhagia, quench one's thirst.Rhizoma Dioscoreae root contains Diosgenin (diosgenin) 0.012%, dopamine (dopamine), hydrochloric acid Rhizoma Dioscoreae alkali (batatasinehydrochloride), polyphenol oxidase (polyphenoloxidase), allantoin (allantoin) stops wooden fork Element (abscisin) II.(glucoprotein) Han glycoprotein again, hydrolyzes: lysine (lysine), histidine (histidine), arginine (arginine), aspartic acid (asparticacid), threonine (threonine), serine (serine), glutamic acid (glutamicacid), proline (proline), glycine (glycine), alanine (alanine), valine (valine), leucine (leucine), isoleucine (isoleucine), cruel propylhomoserin (tyrosine), phenylalanine (phenylalanine) and methionine (methionine).Also containing including above-mentioned aminoacid and Guang Propylhomoserin (cystine), γ-aminobutyric acid (γ-aminobutyricacid) is at interior free amino acid, another containing having blood sugar lowering The polysaccharide of effect, and containing by mannose (mannose), glucose (glucose) and galactose (galactose) in molar ratio 6.45:1:1.26 constitute Chinese yam polysaccharide, again baric, beryllium, cerium, cobalt, chromium, copper, gallium, lanthanum, lithium, manganese, niobium, nickel, phosphorus, strontium, thorium, Titanium, vanadium, yttrium, ytterbium, zinc, zirconium and sodium oxide, potassium oxide, aluminium oxide, ferrum oxide, calcium oxide, magnesium oxide etc..Possibly together with catechol Amine (catecholamine), and cholesterol (cholesterol), ergosterol (ergosterol), campesterol (campesterol), stigmasterol (stigmasterol), cupreol (β-sitosterol).Containing phytic acid in mucus (phyticacid), mannocarolose (mannan) Ia, Ib and Ic.
In some embodiments, the extracting method of described Radix Puerariae and Rhizoma Dioscoreae root extract is, Radix Puerariae and Rhizoma Dioscoreae root is washed Only, pulverize last by Radix Puerariae and weight ratio 1:(0.5-2 of Rhizoma Dioscoreae root) mix homogeneously, use alcohol reflux 2-3h, carry Taking 3-4 time, cold preservation 10-15h, filter, filtrate, through being evaporated to without ethanol, to obtain final product.
During the extraction of Radix Puerariae and Rhizoma Dioscoreae root extract, the ethanol of employing is the ethanol of mass fraction 95%.
Inventor, during completing the present invention, is found surprisingly that Radix Puerariae and Rhizoma Dioscoreae root extract can not only improve hydrolysis Albumen and the glucosan tightening effect to skin, additionally it is possible to improve the stability of compositions, prevent compositions from producing variable color and go bad. Particularly this effect, Radix Puerariae and Rhizoma Dioscoreae root is just had separately to use ethanol extraction with ethanol extraction after Radix Puerariae and Rhizoma Dioscoreae root mix homogeneously, Or mixing after be soaked in water after again with ethanol extraction all without this effect.Inventor speculates that its possible reason is Radix Puerariae and Rhizoma Dioscoreae root When jointly extracting with ethanol after mix homogeneously, it is possible to promote the dissolution of effective ingredient, serve the effect that suppression variable color is rotten.
In the skin care compositions that the present invention provides, in parts by weight, containing Radix Puerariae and Rhizoma Dioscoreae root extract 0.1-0.2 Part.
Radix Oenotherae erythrosepalae oil
No. CAS of Radix Oenotherae erythrosepalae oil is 90028-66-3, and its main component includes gamma-Linolenic acid, magnesium, zinc, copper, injection Vitamin B_6, B6, B5, have multinomial treatment, whitening function, makes that capsule is for oral administration can treat cardiovascular disease, premenstrual syndrome, climacteric Syndrome, is used in aromatotherapy, can be in harmonious proportion emulsion, cream, improves eczema, psoriasis, helps wound healing, and fingernail is sent out Educate, solve hair problem.
In the skin care compositions that the present invention provides, in parts by weight, containing Radix Oenotherae erythrosepalae oil 0.1-0.3 part.
Borage oil
Borage oil, rich in abundant natural gamma linolenic acid, is suitable for the skin of all of skin, especially adult form, is very Good skin renewal agent.
Borage oil can be effectively improved coarse dry and astringent, prevent cell water loss, increase the whitest sense of skin.Can repair Damaged cell, improves the self-maintenance ability of cell, and jointly acts on cellular matrix, be built into holomyarian skin barrier, make skin Present full, compact, healthy.
In the skin care compositions that the present invention provides, in parts by weight, containing borage oil 0.1-0.3 part.
Radix Oenotherae erythrosepalae oil and borage oil contain the unsaturated fatty acids such as abundant gamma-Linolenic acid, oleic acid, linoleic acid, are used for In cosmetics, there is nourishing and moistening skin, delay skin aging etc. act on.
Lac regis apis extract
Lac regis apis, has another name called Lac regis apis, Lac regis apis breast, queen bee breast, Lac regis apis, is the young worker bee pharynx gland cultivating larva in honeycomb Secretions, is supplied with becoming the food of the larva of queen bee, is also the lifelong food of queen bee.
Lac regis apis contains a certain amount of acetylcholine, can make to play a role in health care the nervous system of human body;Lac regis apis rich in Vitamin B and high quality protein, particularly containing the royal jelly acid that sterilizing power is strong, thus be good medicine for cancer;Lac regis apis has promotion hemopoietic Function, can increase hemoglobin, promotes growth, improves premunition;Lac regis apis is contained within pantothenic acid, can improve rheumatism and pass Joint symptom.Lac regis apis sample peptides Han para-insulin, its molecular weight is identical with bovine insulin, has the islet function of diabetics Preferably regulatory function;Lac regis apis can strengthen adrenal cortex function, regulates human hormone, brain cell between activation, is conducive to treatment Climacteric disfunction and chronic prostatitis syndrome.Lac regis apis can strengthen the basis muscle power of people, makes human senility tissue activate, after clothes Appetite is good, and long spirit, complexion is good.Peptide contained by Lac regis apis and protein-based healthy ingredient, can promote intelligent development, thus take can Improve memory.Lac regis apis contains proteohormone and natural antibiotics, can play and prevent infection, promotion thin when smearing treatment scald Born of the same parents generate, the effect of rear preventing from scar;Lac regis apis contains plurality of inorganic salt, can promote that glycogen discharges, and promotes metabolism, thus permissible Beauty treatment, eliminates speckle.Lac regis apis has effect of good regulation blood fat.
Lac regis apis extract for the present invention can be that Lac regis apis passes through extraction side well-known to those skilled in the art Method obtains.Can also be to buy from market.
In the skin care compositions that the present invention provides, in parts by weight, containing Lac regis apis extract 0.05-0.1 part.
Rose extract
Rose extract is the dry flower extract of Se Bi section plant Flos Rosae Rugosae.Its character is gentle, can chill out, balance in Secretion, replenishing blood and vital energy, U.S. face skin protection, liver and stomach are had conditioning effect and can allaying tiredness, improve body constitution, the taste of rose tea Road delicate fragrance is quiet and tastefully laid out, can make us chilling out, relieving depression, can improve endocrine disturbance, releases sore waist and aching in the waist and the back, to allaying tiredness and Wound healing, moistens skin care, improves looks, invigorates blood circulation, the liver protecting, stomach function regulating nourishing the liver, allaying tiredness, the merit of blood circulation promoting Energy.Adjustable treating blood disorders gas, blood circulation promoting, energy blood circulation promoting and blood stasis dispelling, can chill out, adjust endocrine.
In some embodiments, the extracting method of described rose extract is, weighs Flos Rosae Rugosae powder, adds ethanol, leaching Using extracting through microwave heating 2-3 time after bubble 2-3h, filter, filtrate, through being evaporated to without ethanol, to obtain final product.
In the skin care compositions that the present invention provides, in parts by weight, containing rose extract 0.1-0.2 part.
The second aspect of the invention provides the application in producing cosmetics of a kind of skin care compositions as above.
The third aspect of the invention provides a kind of cosmetics, wherein contains skin care compositions as above.
Term " cosmetics " refers to smear, spray or other similar approach, intersperses among any position of human body surface, Such as skin, hair, refer to toenail, lips and teeth etc., to reach to clean, maintain, improve looks, modify and change outward appearance, or revise people's bromhidrosis Taste, the chemical industrial product for the purpose of maintaining a good state or fine chemical product.
Cosmetics are divided into liquid, emulsion, cream kind, powder class, bulk, oily according to dosage form.The example of liquid include but not It is limited to Cleansing Foam, body lotion, shampoo, astringent, perfume, clarifying lotion, makeup removing liquid, essence, stock solution etc.;The example of emulsion includes But it is not limited to mel, milk, hair care breast, elite breast;The example of cream kind include but not limited to moisten facial cream, vanishing cream, hair cream, Frost before concealer, hair cream, essence cream, adornment;The example of powder class includes but not limited to XIANGFEN, talcum powder, loose powder, clean skin powder, honey Powder;Block example includes but not limited to muffin, cosmetic container, lipstick, pomade;The example of oily include but not limited to makeup remover, Soothing oil, brilliantine, essential oils.
In some embodiments, the skin care compositions described above weight content in these cosmetics is 0.5%-20%.
In some embodiments, cosmetics as above, it compacts frost for paste.
In some embodiments, paste as above a kind of compacts frost, wherein, containing above-mentioned skin care compositions, Oil-soluble ingredients, emulsifying agent, polyhydric alcohol, thickening agent, pH adjusting agent, water.
Oil-soluble ingredients
As oil-soluble ingredients used in the present invention, can enumerate: synthesis ester oil, silicone oil, higher fatty acids etc., it is possible to use More than any one in these.Above material state at normal temperatures can be aqueous, semi-solid and any one in solid, It is not particularly limited.
As synthesis ester oil, such as, can enumerate: caproic acid 2-amyl group nonyl ester, caproic acid 2-hexyl ester in the last of the ten Heavenly stems, caproic acid 2-heptyl ten One Arrcostab, caproic acid 2-octyldodecyl, caproic acid isooctadecane base ester, octanoic acid 2-butyl monooctyl ester, octanoic acid isotridecyl Ester, octanoic acid 2-amyl group nonyl ester, octanoic acid 2-hexyl ester in the last of the ten Heavenly stems, octanoic acid 2-heptylundecanoic base ester, octanoic acid 2-octyldodecyl, pungent Sour isooctadecane base, capric acid 2-Propylheptyl, capric acid 2-butyl monooctyl ester, capric acid isotridecyl ester, capric acid 2-amyl group nonyl ester, the last of the ten Heavenly stems Acid 2-hexyl ester in the last of the ten Heavenly stems, capric acid 2-heptylundecanoic base ester, capric acid 2-octyldodecyl, capric acid isooctadecane base ester, Laurel Acid 2-Propylheptyl, lauric acid different nonyl ester, lauric acid 2-butyl monooctyl ester, lauric acid isotridecyl ester, the different tridecane of lauric acid Base ester, lauric acid 2-amyl group nonyl ester, lauric acid 2-hexyl ester in the last of the ten Heavenly stems, lauric acid 2-heptylundecanoic base ester, lauric acid 2-octyl group ten Dialkyl, lauric acid isotridecyl ester, lauric acid isooctadecane base ester, isopropyl myristate, myristic acid 2-ethyl Own ester, myristic acid different nonyl ester, myristic acid 2-Propylheptyl, myristic acid 2-butyl monooctyl ester, myristic acid isotridecyl Ester, myristic acid 2-amyl group nonyl ester, myristic acid 2-hexyl ester in the last of the ten Heavenly stems, myristic acid 2-heptylundecanoic base ester, myristic acid 2- Octyldodecyl, myristic acid isooctadecane base ester, isobutyl palmitate, Palmic acid 2-Octyl Nitrite, the different nonyl of Palmic acid Ester, Palmic acid 2-Propylheptyl, Palmic acid 2-butyl monooctyl ester, Palmic acid isotridecyl ester, Palmic acid 2-amyl group nonyl ester, Petiolus Trachycarpi Acid 2-hexyl ester in the last of the ten Heavenly stems, Palmic acid 2-heptylundecanoic base ester, Palmic acid 2-octyldodecyl, Palmic acid isooctadecane base Ester, isopropyl stearate, isobutyl stearate, stearic acid 2-Octyl Nitrite, stearic acid different nonyl ester, stearic acid 2-Propylheptyl, Stearic acid 2-butyl monooctyl ester, stearic acid isotridecyl ester, stearic acid 2-amyl group nonyl ester, stearic acid 2-hexyl ester in the last of the ten Heavenly stems, stearic acid 2-heptylundecanoic base ester, stearic acid 2-octyldodecyl, stearic acid isooctadecane base ester, docosane isopropyl propionate, Behenic acid isobutyl ester, behenic acid 2-Octyl Nitrite, behenic acid different nonyl ester, behenic acid 2-Propylheptyl, Behenic acid 2-butyl monooctyl ester, behenic acid isotridecyl ester, behenic acid 2-amyl group nonyl ester, behenic acid 2- Hexyl ester in the last of the ten Heavenly stems, behenic acid 2-heptylundecanoic base ester, behenic acid 2-octyldodecyl, behenic acid different ten Eight Arrcostabs, 2 ethyl hexanoic acid dodecyl ester, 2 ethyl hexanoic acid myristyl ester, 2 ethyl hexanoic acid cetyl ester, 2-second Base caproic acid stearyl, 2 ethyl hexanoic acid 2-Propylheptyl, 2 ethyl hexanoic acid 2-butyl monooctyl ester, the different tridecane of 2 ethyl hexanoic acid Base ester, 2 ethyl hexanoic acid 2-amyl group nonyl ester, 2 ethyl hexanoic acid 2-hexyl ester in the last of the ten Heavenly stems, 2 ethyl hexanoic acid 2-heptylundecanoic ester, 2-second Base caproic acid 2-octyldodecyl ester, 2 ethyl hexanoic acid isooctadecane base ester, isononyl isononanoate, different n-nonanoic acid dodecyl ester, different N-nonanoic acid myristyl ester, different n-nonanoic acid cetyl ester, different n-nonanoic acid stearyl, different n-nonanoic acid docosyl ester, different n-nonanoic acid 2- Butyl monooctyl ester, different n-nonanoic acid isotridecyl ester, different n-nonanoic acid 2-amyl group nonyl ester, different n-nonanoic acid 2-hexyl ester in the last of the ten Heavenly stems, different n-nonanoic acid 2-heptyl ten One Arrcostab, different n-nonanoic acid 2-octyldodecyl, different n-nonanoic acid isooctadecane base ester, different decyl decylate, isodecyl acid undecyl The acid of ester, isodecyl acid dodecyl ester, isodecyl acid myristyl ester, isodecyl acid cetyl ester, isodecyl acid stearyl, isodecyl 2-Propylheptyl, isodecyl acid 2-butyl monooctyl ester, isodecyl acid isotridecyl ester, isodecyl acid 2-amyl group nonyl ester, isodecyl acid 2-hexyl The last of the ten Heavenly stems ester, isodecyl acid 2-heptylundecanoic base, isodecyl acid 2-octyldodecyl, isodecyl acid isooctadecane base ester, different tridecane The misery ester of base heptyl heptylate, isotridecyl, isotridecyl acid nonyl ester, isotridecyl acid ester in the last of the ten Heavenly stems, isotridecyl acid 11 Arrcostab, isotridecyl acid dodecyl ester, isotridecyl acid myristyl ester, isotridecyl acid cetyl ester, Isotridecyl acid stearyl, isotridecyl isopropyl propionate, isotridecyl acid isobutyl ester, isotridecyl acid 2-second The own ester of base, isotridecyl acid 2-Propylheptyl, isotridecyl acid 2-butyl monooctyl ester, isotridecyl acid isotridecyl Ester, isotridecyl acid 2-amyl group nonyl ester, isotridecyl acid 2-hexyl ester in the last of the ten Heavenly stems, isotridecyl acid 2-heptylundecanoic base Ester, isotridecyl acid 2-octyldodecyl, isotridecyl acid isooctadecane base ester, isostearic acid propyl ester, different tristearin Acid butyl ester, isostearic acid pentyl ester, the own ester of isostearic acid, isostearic acid heptyl ester, isostearic acid monooctyl ester, isostearic acid nonyl ester, different firmly Fat acid ester in the last of the ten Heavenly stems, isostearic acid undecyl ester, isostearic acid dodecyl ester, isostearic acid myristyl ester, isostearic acid ten Six Arrcostabs, isostearic acid stearyl, isopropyl isostearate, isostearic acid isobutyl ester, isostearic acid 2-Octyl Nitrite, Isostearic acid 2-Propylheptyl, isostearic acid 2-butyl monooctyl ester, isostearic acid isotridecyl ester, isostearic acid 2-amyl group nonyl Ester, isostearic acid 2-hexyl ester in the last of the ten Heavenly stems, isostearic acid 2-heptylundecanoic base ester, isostearic acid 2-octyldodecyl, different firmly Fat acid isooctadecane base ester, oleic acid propyl ester, butyl oleate, amyl oleate, hexyl oleate, oleic acid heptyl ester, oleic acid monooctyl ester, oleic acid nonyl Ester, decyl oleate, oleic acid undecyl ester, oleic acid dodecyl ester, oleic acid myristyl ester, oleic acid cetyl ester, oleic acid Stearyl, acid isopropyl, tebelon, oleic acid 2-Octyl Nitrite, oleic acid 2-Propylheptyl, oleic acid 2-butyl are pungent Ester, oleic acid isotridecyl ester, oleic acid 2-amyl group nonyl ester, oleic acid 2-hexyl ester in the last of the ten Heavenly stems, oleic acid 2-heptylundecanoic base ester, oleic acid 2- Octyldodecyl, oleic acid isooctadecane base ester, isononyl isononanoate, different isodecyl pelargonate, isopropyl myristate, Petiolus Trachycarpi Isopropyl propionate, butyl stearate, lauric acid hexyl ester, myristyl myristate base ester, dimethyl octanoic acid hexyl ester in the last of the ten Heavenly stems, lactic acid 16 Arrcostab, lactic acid myristyl ester, lactic acid octyldodecyl, acetic acid lanoline, 12-hydroxy stearic acid cholesteryl ester, 12- Hydroxy stearic acid plant sterol ester, oleic acid plant sterol ester, two-2 ethyl hexanoic acid glycol ester, dipentaerythritol fatty acid ester, Single isostearic acid alkyl diol ester, diethyl caproic acid DOPCP, two capric acid DOPCP, two-2-heptyl undecanoic acids are sweet Grease, four-2 ethyl hexanoic acid pentaerythritol ester, four isostearic acid pentaerythritol esters, three-2 ethyl hexanoic acid glyceride, three (pungent Acid/capric acid) glyceride, three glyceryl isostearates, three (caprylic/capric/myristic acid/stearic acid) glyceride, three Semen Myristicaes Acid glyceride, tricaprylin, decanoin, three-2-heptyl undecanoic acid glyceride, three isostearic acid trihydroxy methyls third Alkane, three-2 ethyl hexanoic acid trimethylolpropane, (isostearic acid/decanedioic acid) double trimethylolpropane oligoester, erithritol three second Base alkyl caproate, dipentaerythritol trimerization hydroxy stearic acid ester, isostearic acid Sargassum sugar ester, dipentaerythritol five isostearate, Three isostearic acid two glyceride, four isostearic acid two glyceride, malic acid two isooctadecane base ester, Castor Oil Fatty Acid methyl ester, Lanolin fatty isopropyl propionate, aceto-glyceride, diisobutyl adipate, (thylhexoic acid/stearic acid/adipic acid) glyceride, (hexyldecanoic acid/decanedioic acid) two glycerol oligoester, N-lauroyl-Pidolidone-2-octyldodecyl, adipic acid two- 2-heptylundecanoic base ester, lauric acid hexyl ester, ethyl laurate, Diisooctyl Sebacate, myristic acid 2-hexyl last of the ten Heavenly stems Ester, Palmic acid 2-hexyl ester in the last of the ten Heavenly stems, adipic acid 2-hexyl ester in the last of the ten Heavenly stems, Dermol DIPS, succinic acid 2-Octyl Nitrite, three different Petiolus Trachycarpis Acid glyceride, ethyl acetate, butyl acetate, triethyl citrate, three (behenic acid/isostearic acid/eicosane diacids) are sweet Grease, (behenic acid/eicosane diacid) glyceride and (behenic acid/eicosane diacid) polyglycerin ester etc..
As silicone oil, such as, can enumerate: the poly-silicon of dimethyl polysiloxane, methyl phenyl silicone and methyl hydrogen The chain polysiloxanes such as oxygen alkane;Octamethylcy-clotetrasiloxane, decamethylcyclopentaandoxane, ten diformazan basic ring six siloxanes and tetrahydrochysenes The cyclic polysiloxanes such as tetramethyl-ring tetrasiloxane;And polyoxyethylene polyalkylsiloxane etc..
As higher fatty acids, such as, can enumerate: lauric acid, myristic acid, Palmic acid, stearic acid, behenic acid (20 Two alkanoic acids), oleic acid, 9-undecylenic acid, your acid, isostearic acid, linoleic acid, linolenic acid, eicosapentaenoic acid (EPA) and 20 appropriate Two carbon acids (DHA) etc..
Emulsifying agent
As emulsifying agent used in the present invention, can list such as: polyoxyethylene (POE)-sorbitan list oleic acid Ester, POE-sorbitan monostearate, POE-dehydrated sorbitol mono-fatty acid ester and POE-sorbitan four oil The POE-sorbitan fatty acid esters classes such as acid esters;POE-is sorbityl monododecanoate, POE-sorbitol monooleate, The POE-sorbitan fatty acid esters such as POE-Sorbitol five oleate and POE-sorbitan monostearate;POE-glycerol The POE-glycerine fatty acid esters such as monostearate, POE-glycerol monoisostearate and POE-glyceryl triisostearate; The POE-fatty acid esters such as POE-monoleate, POE-distearate, the mono-dioleate of POE-and diglycol stearate; POE-Laurel ether, POE-oil ether, POE-stearyl ether, POE-behenyl base ether, POE-2-octyldodecyl ether and POE-cholestane The POE-alkyl ethers such as alcohol ether;The Pluronic classes such as Pluronic;POE POP-cetyl ether, POE POP-2-decyl ten The POE POP-alkane such as tetraalkyl ether, POE POP-single-butyl ether, POE POP-hydrogenated lanolin and POE POP-glycerin ether Base ethers;Tetronic etc. four POE tetra-POP-ethylenediamine polymerization species;POE-castor oil hydrogenated, POE-castor oil hydrogenated list Isostearate, POE-castor oil hydrogenated three isostearate, POE-castor oil hydrogenated list pyroglutamic acid list isostearic acid diester With POE-Oleum Ricini castor oil hydrogenated derivants such as POE-castor oil hydrogenated maleic acids;The POE-honeybees such as POE-Sorbitol Cera Flava Wax lanolin derivative;Cocoanut fatty acid diethanolamide, lauric monoethanolamide and fatty acid isopropanol amide etc. Alkanolamide;POE-methyl glycol fatty acid ester;POE-alkylamine;POE-fatty acid amide;Sucrose fatty acid ester;POE-nonyl benzene Base yuban;Alkyl ethoxy dimethyl amine;And, three oleyl alcohol phosphate esters etc..
Can also be lauryl alcohol, spermol, stearyl alcohol, tadenan, myristyl alcohol, oleyl alcohol and cetearyl alcohol Deng straight chain alcohol;And single batiolum (batilol), 2-decyl tetradecanol, lanolin alcohol, cholesterol, pohytol, The branched-chain alcohos etc. such as hexyl dodecanol, isooctadecanol and octyldodecanol.
Polyhydric alcohol
In the present invention, polyhydric alcohol is not particularly limited, can enumerate: 1,3 butylene glycol, 3-methyl isophthalic acid, 3-butanediol, 1, Ammediol, dipropylene glycol, ethohexadiol, hexanediol, glycerol, two glycerol, erythritol, tetramethylolmethane, dipentaerythritol, Pyrusussuriensis Sugar alcohol, glucose, galactose, fructose, maltose and trehalose etc..Above-mentioned polyhydric alcohol can be used alone one, it is also possible to It is applied in combination two or more.
Thickening agent
As above-mentioned thickening agent, can list: can enumerate guar gum, tracasol, WENBO seed, carrageenan, galactan, Ah Draw primary glue, tara gum, tamarind, Furcellaran, karaya, Hibisci Mutabilis, Lignum Aquilariae Resinatum wood glue, Tragacanth, pectin, pectic acid and sodium Salt, the mannans such as the salt such as salt, alginic acid and sodium salt;The starch such as rice, Semen Maydis, Rhizoma Solani tuber osi, Semen Tritici aestivi;Xanthan gum, dextran, amber Amber acyl glucosan, curdlan, hyaluronic acid and salt, xanthan gum, amylopectin, gellan gum, chitin, chitosan, fine jade Fat, brown alga extract, chondroitin sulfate, casein, collagen protein, gelatin, albumin;Methylcellulose, ethyl cellulose, hydroxyl second Salt, methylhydroxypropylcellulose, the cellulose sulfates such as base cellulose, hydroxy propyl cellulose, carboxymethyl cellulose and sodium thereof The cellulose and its derivates such as sodium, dialkyl dimethyl ammonium sulfate cellulose, crystalline cellulose, cellulose end;Soluble starch, The starch-series macromolecules such as carboxymethyl starch, methylhydroxy propyl group starch, methyl starch, trimethyl ammonium chloride starch, The starch derivatives such as ocentyl succinic corn starch aluminum;The alginic acid derivatives such as sodium alginate, alginic acid propylene glycol ester;Poly-second Vinyl pyrrolidone (PVP), polyvinyl alcohol (PVA), vinyl pyrrolidone ethenol copolymer, polyvinyl methyl ether; Polyethylene Glycol, polypropylene glycol, poloxalkol;(methylacryoyloxyethyl carboxybetaine/methyl-prop Olefin(e) acid Arrcostab) both sexes such as copolymer, (acrylate/stearyl acrylate ester/methacrylic acid ethylamine oxide) copolymer Methacrylate copolymer;(dimethicone/vinyl dimethicone) cross linked polymer, (alkyl acrylate/ Diacetone acrylamide) copolymer, (alkyl acrylate/diacetone acrylamide) copolymer A MP;Polyvinyl acetate base section Saponified, maleic acid;Vinyl pyrrolidone methacrylates copolymer;Acrylic acid tree Fat alkanolamine;Polyester, water-dispersible polyester;Polyacrylamide;Acrylate copolymer, the carboxy vinyl such as polyacrylic acid ethyl Salt, the acrylate methacrylate copolymers such as based polyalcohol, polyacrylic acid and sodium salt thereof;Acrylic arid methacrylic acid alkane Base ester copolymer;The diallyldimethylammonium chloride propylene such as Poise C-80M, polyquaternary ammonium salt-7 such as Polyquaternium-10 The propylene such as the acrylic acid diallyldimethylammonium chloride copolymer such as amide copolymer, Merquat 280, polyquaternary ammonium salt-39 Diene acid diallyidimethylammonium chloride acrylamide copolymer, acrylic acid cationization methacrylate copolymer, The acrylic methyl ester chlorination first such as acrylic acid cationization methacrylic copolymer, polyquaternary ammonium salt-47 Base acrylamido propyl trimethyl ammonium copolymer, methacrylic acid chloride cholinester polymer;Cationization oligosaccharide, cationization The cationised polysaccharide classes such as dextran, guar gum trimethyl ammonium chloride;Polymine;Cationic polymer; The copolymerization such as the polymer of polyquaternary ammonium salt-51 2-methylacryoyloxyethyl Phosphorylcholine such as grade and butyl methacrylate copolymer Thing;Emulsion acrylic resin, polyethyl acrylate emulsion, polyalkyl acrylate emulsion, polyvinyl acetate base ester resin emulsion, The macromolecule emulsion such as natural rubber latex, synthetic latex;NC Nitroncellulose;Polyurethanes and various copolymer;Various silicones; The various copolymers of silicone-based such as acrylic compounds-silicone graft copolymer;Various fluorine systems macromolecule;12-hydroxy stearic acid and salt thereof; The dextrin fatty acid esters such as Dextrin palmitate, myristic acid dextrin;Silicic acid anhydride, aerosil (ultra micron silicic acid anhydride), silicic acid Magnalium, sodium silicate magnesium, metallic soap, Acidic phosphates slaine, bentonite, Strese Hofmann's hectorite., organo-clay mineral, Sucrose Fatty Acid Ester Fat acid esters, oligofructose fatty acid ester.
PH adjusting agent
As above-mentioned pH adjusting agent, can list: edetic acid, disodium edetate, citric acid, sodium citrate, sodium hydroxide, hydrogen Potassium oxide and triethanolamine etc..PH adjusting agent can be used alone, and maybe can be applied in combination two or more.
The fourth aspect of the invention provide a kind of prepare a kind of paste as above compact frost method, including following Step:
(1) adding oil-soluble ingredients, emulsifying agent, Radix Oenotherae erythrosepalae oil, borage oil, be heated to 80-90 DEG C, dissolve completely, stirring is all As A phase after even.
(2) by pH adjusting agent water dissolution, standby as B phase.
(3) add thickening agent, water, until completely dissolved, add polyhydric alcohol, glucosan, trehalose, be heated to 80-90 DEG C, Dissolve completely, as C phase after stirring.
(4) A is added to C phase, vacuum homogenizing 3-10min, start cooling.
(5) treat that temperature is down to 40-50 DEG C, add Radix Puerariae and Rhizoma Dioscoreae root extract, hydrolyzed protein, Lac regis apis extract, rose Rare extract, is stirring evenly and then adding into B phase, stirs, cooling.
(6) treat that temperature is down to 30-40 DEG C, discharging, to obtain final product.
Embodiment
A1 hydrolyzed protein, mean molecule quantity 10000Da, containing the acidic amino acid of 33 weight %, Wuxi star marine growth section Skill company limited
A2 hydrolyzed protein, mean molecule quantity 10000Da, containing the acidic amino acid of 20 weight %, Wuxi star marine growth science and technology has Limit company
A3 hydrolyzed protein, mean molecule quantity 10000Da, containing the acidic amino acid of 50 weight %, Wuxi star marine growth science and technology has Limit company
A4 hydrolyzed protein, mean molecule quantity 10000Da, containing the acidic amino acid of 10 weight %, Wuxi star marine growth science and technology has Limit company
A5 hydrolyzed protein, mean molecule quantity 10000Da, containing the acidic amino acid of 70 weight %, Wuxi star marine growth science and technology has Limit company
B glucosan, Yu Xin bio tech ltd, Guangzhou
C trehalose, Ai Nuosen bio tech ltd, Wuhan
D1 Radix Puerariae and Rhizoma Dioscoreae root extract
Extracting method is: Radix Puerariae and Rhizoma Dioscoreae root are cleaned, and pulverizes last equal by the weight ratio 1:1 mixing of Radix Puerariae and Rhizoma Dioscoreae root Even, to use alcohol reflux 2.5h, extract 3 times, cold preservation 12h, filter, filtrate, through being evaporated to without ethanol, to obtain final product.
D2 Radix Puerariae and Rhizoma Dioscoreae root extract
Extracting method is: Radix Puerariae and Rhizoma Dioscoreae root are cleaned, and pulverizes last by the weight ratio 1:0.5 mixing of Radix Puerariae and Rhizoma Dioscoreae root Uniformly, using alcohol reflux 2.5h, extract 3 times, cold preservation 12h, filter, filtrate, through being evaporated to without ethanol, to obtain final product.
D3 Radix Puerariae and Rhizoma Dioscoreae root extract
Extracting method is: Radix Puerariae and Rhizoma Dioscoreae root are cleaned, and pulverizes last equal by the weight ratio 1:2 mixing of Radix Puerariae and Rhizoma Dioscoreae root Even, to use alcohol reflux 2.5h, extract 3 times, cold preservation 12h, filter, filtrate, through being evaporated to without ethanol, to obtain final product.
D4 Radix Puerariae and Rhizoma Dioscoreae root extract
Extracting method is: Radix Puerariae and Rhizoma Dioscoreae root are cleaned, and pulverizes last by the weight ratio 1:0.1 mixing of Radix Puerariae and Rhizoma Dioscoreae root Uniformly, using alcohol reflux 2.5h, extract 3 times, cold preservation 12h, filter, filtrate, through being evaporated to without ethanol, to obtain final product.
D5 Radix Puerariae and Rhizoma Dioscoreae root extract
Extracting method is: Radix Puerariae and Rhizoma Dioscoreae root are cleaned, and pulverizes last equal by the weight ratio 1:5 mixing of Radix Puerariae and Rhizoma Dioscoreae root Even, to use alcohol reflux 2.5h, extract 3 times, cold preservation 12h, filter, filtrate, through being evaporated to without ethanol, to obtain final product.
D6 Radix Puerariae and Rhizoma Dioscoreae root extract
Extracting method is: Radix Puerariae and Rhizoma Dioscoreae root are cleaned, and pulverizing last is claimed respectively by weight ratio 1:1 of Radix Puerariae and Rhizoma Dioscoreae root Amount, uses alcohol reflux 2.5h respectively, extracts 3 times, cold preservation 12h, filters, and filtrate, through being evaporated to without ethanol, obtains Pueraria lobota Root extract and Rhizoma Dioscoreae root extract, then Radix Puerariae extract and Rhizoma Dioscoreae root extract are mixed, obtain Radix Puerariae and Rhizoma Dioscoreae root extracts Thing.
D7 Radix Puerariae and Rhizoma Dioscoreae root extract
Extracting method is: Radix Puerariae and Rhizoma Dioscoreae root are cleaned, and pulverizes last equal by the weight ratio 1:1 mixing of Radix Puerariae and Rhizoma Dioscoreae root Even, at room temperature soak 10h with clear water, then filter, powder is used alcohol reflux 2.5h, extract 3 times, cold preservation 12h, mistake Filter, filtrate, through being evaporated to without ethanol, to obtain final product.
D8 Radix Puerariae extract
Extracting method is: cleaned by Radix Puerariae, and pulverize last alcohol reflux 2.5h, extracts 3 times, cold preservation 12h, mistake Filter, filtrate, through being evaporated to without ethanol, to obtain final product.
D9 Rhizoma Dioscoreae root extract
Extracting method is: cleaned by Rhizoma Dioscoreae root, and pulverize last alcohol reflux 2.5h, extracts 3 times, cold preservation 12h, mistake Filter, filtrate, through being evaporated to without ethanol, to obtain final product.
E Radix Oenotherae erythrosepalae oil, the Guangzhou Chinese one hundred this daily use chemicals developments in science and technology company limited
F borage oil, the Guangzhou Chinese one hundred this daily use chemicals developments in science and technology company limited
G Lac regis apis extract, Herba Asparagi Setacei bio tech ltd, Xi'an
H rose extract
Extracting method is: weigh Flos Rosae Rugosae powder, adds ethanol, uses extracting through microwave heating 3 times, filter, filtrate after soaking 2.5h Through being evaporated to without ethanol, to obtain final product.
In embodiment 1-5, the parts by weight of each component are shown in Table 1.
Table 1
In comparative example 1-9, the parts by weight of each component are shown in Table 2.
Table 2
Embodiment 6-10 or comparative example 10-18 are respectively the paste containing embodiment 1-5 or comparative example 1-9 and compact cream cosmetic. Wherein, oil-soluble ingredients be 15 weight portion cetearyl alcohol ethylhexoates (France enlightening win DUB LIQUIDE 85 DOB) and 4.5 weight portion polydimethylsiloxane (DOW CORNING DC200/100);Emulsifying agent is that (Fanyu, Guangzhou joins 2 weight portion stereth Close Persil Chemical Co., Ltd.), 2 weight portion PEG-100 stearates (Shanghai Bei Ke Chemical Co., Ltd.) and 3 weight portion spermaceti Stearyl alcohol (Guangzhou Shi Ming Chemical Co., Ltd.);Polyhydric alcohol is that (it is limited that glad chemical science and technology is won in Guangzhou to 1.8 weight portion 1,3 butylene glycols Company), (the Guangzhou prosperous chemical industry of brocade has for 2.8 parts by weight of propylene glycol (Guangzhou Jin Wang Chemical Co., Ltd.) and 0.8 parts by weight of glycerin Limit company);Thickening agent is 0.4 weight portion carbomer (Guangzhou Heng Chuan Chemical Co., Ltd.);PH adjusting agent is 0.35 weight portion Triethanolamine (Guangzhou Yin Lin Chemical Co., Ltd.);65 weight parts waters.
The preparation method of embodiment 6-10 and comparative example 10-18 is:
(1) add oil-soluble ingredients, emulsifying agent, Radix Oenotherae erythrosepalae oil, borage oil, be heated to 85 DEG C, dissolve completely, after stirring As A phase.
(2) pH adjusting agent is used a small amount of water dissolution, standby as B phase.
(3) add thickening agent, water, until completely dissolved, add polyhydric alcohol, glucosan, trehalose, be heated to 80-90 DEG C, Dissolve completely, as C phase after stirring.
(4) A is added to C phase, vacuum homogenizing 5min, start cooling.
(5) treat that temperature is down to 45 DEG C, add Radix Puerariae and Rhizoma Dioscoreae root extract, hydrolyzed protein, Lac regis apis extract, Flos Rosae Rugosae carry Take thing, be stirring evenly and then adding into B phase, stir, cooling.
(6) treat that temperature is down to 35 DEG C, discharging, to obtain final product.
In the preparation process of embodiment 6-10 and comparative example 10-18, the selection of each component and parts by weight are according to table 1 He Component in table 2 and parts by weight respective change.
One, stability test
Embodiment 6-10 and comparative example 10-18 are at room temperature stood 6 months, observes color change.
Observed result: embodiment 6-10 color keeps constant;Comparative example 10-18 becomes brown from pink colour.
Two, efficacy test
1. volunteer chooses
Select 168 ages volunteer between 21-50 year, wherein each 28 of the masculinity and femininity in 21-30 year;31-40 year Each 28 of masculinity and femininity;Each 28 of the masculinity and femininity in 41-50 year.Volunteer is divided into 14 groups, often organizes 12 people, wherein Each 2 of the masculinity and femininity in 21-30 year;Each 2 of the masculinity and femininity in 31-40 year;Each 2 of the masculinity and femininity in 41-50 year.Will Group is designated as 1-14 group.
2. using method
1-5 group uses embodiment 6-10 respectively, and 6-14 group uses comparative example 10-18 respectively.After conventional face cleaning, smear Semen Glycines The consumption of size in face, is as the criterion forming thin layer, the most each uses once, uses 6 months continuously.
3. sensory evaluation
Wrinkle: substantially desalination is 10 points, is 0 point without significant change, according to desalination degree difference be designated as 0-10/, record is often Organize the meansigma methods taken after 6 people give a mark respectively.
Compacting: skin-tightening feels to be evident as 10 points, skin-tightening sensation is 0 point without significant change, according to sensation of compacting Degree difference be designated as 0-10/, record meansigma methods of taking after often 6 people of group give a mark respectively.
Evaluation result is listed in table 3
4. skin elasticity test
Use Derma-Expert MC760 skinanalysis apparatus to measure and use 1 month, 3 months, volunteer both sides cheek after 6 months The increments of skin elasticity value, often 6 people of group average rank rear in table 3.
Table 3
It can be seen that the 1st group of best results of embodiment 6 used, i.e. the skin care compositions energy of embodiment 1 from test result Enough make skin more compact flexible, and effectively desalinate wrinkle, simultaneously contained by Radix Puerariae and Rhizoma Dioscoreae root extract stably protecting While skin compositions, it is effectively improved skin effect.
The above, only presently preferred embodiments of the present invention, it is not intended to limit protection scope of the present invention.Every The impartial change done according to present invention and modification, be encompassed by the scope of the claims of the present invention.

Claims (10)

1. a skin care compositions, in parts by weight, by hydrolyzed protein 0.03-0.05 part, glucosan 0.2-0.5 part, trehalose 0.1-0.3 part, Radix Puerariae and Rhizoma Dioscoreae root extract 0.1-0.2 part, Radix Oenotherae erythrosepalae oil 0.1-0.3 part, borage oil 0.1-0.3 part, honeybee Royal jelly extract 0.05-0.1 part, rose extract 0.1-0.2 part composition.
2. skin care compositions as claimed in claim 1, it is characterised in that the mean molecule quantity of described hydrolyzed protein is 5000- 15000Da, contains the acidic amino acid of 20 weight %-50 weight % in described hydrolyzed protein.
3. skin care compositions as claimed in claim 1, it is characterised in that described Radix Puerariae and the extracting method of Rhizoma Dioscoreae root extract For, Radix Puerariae and Rhizoma Dioscoreae root are cleaned, pulverize last by Radix Puerariae and weight ratio 1:(0.5-2 of Rhizoma Dioscoreae root) mix homogeneously, use Alcohol reflux 2-3h, extracts 3-4 time, cold preservation 10-15h, filters, and filtrate, through being evaporated to without ethanol, to obtain final product.
4. skin care compositions as claimed in claim 1, it is characterised in that the extracting method of described rose extract is, weighs Flos Rosae Rugosae powder, adds ethanol, uses extracting through microwave heating 2-3 time, filter after soaking 2-3h, and filtrate is through being evaporated to without second Alcohol, to obtain final product.
5. the application in producing cosmetics of the skin care compositions as described in claim any one of claim 1-4.
6. cosmetics, wherein contain the skin care compositions as described in claim any one of claim 1-4.
7. cosmetics as claimed in claim 6, it is characterised in that described skin care compositions weight content in these cosmetics For 0.5%-20%.
Cosmetics the most as claimed in claims 6 or 7, it compacts frost for paste.
9. paste as claimed in claim 8 a kind of compacts frost, it is characterised in that containing power as any one of claim 1-4 Skin care compositions described in profit requirement, oil-soluble ingredients, emulsifying agent, polyhydric alcohol, thickening agent, pH adjusting agent, water.
10. one kind prepare a kind of paste as claimed in claim 8 or 9 compact frost method, it is characterised in that include following step Rapid:
(1) adding oil-soluble ingredients, emulsifying agent, Radix Oenotherae erythrosepalae oil, borage oil, be heated to 80-90 DEG C, dissolve completely, stirring is all As A phase after even.
(2) by pH adjusting agent water dissolution, standby as B phase.
(3) add thickening agent, water, until completely dissolved, add polyhydric alcohol, glucosan, trehalose, be heated to 80-90 DEG C, dissolve Completely, as C phase after stirring.
(4) A is added to C phase, vacuum homogenizing 3-10min, start cooling.
(5) treat that temperature is down to 40-50 DEG C, add Radix Puerariae and Rhizoma Dioscoreae root extract, hydrolyzed protein, Lac regis apis extract, Flos Rosae Rugosae carry Take thing, be stirring evenly and then adding into B phase, stir, cooling.
(6) treat that temperature is down to 30-40 DEG C, discharging, to obtain final product.
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CN108721186A (en) * 2018-08-02 2018-11-02 江西登云健康美业互联有限公司 A kind of anti-ageing face cream and preparation method thereof
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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108283603A (en) * 2018-04-02 2018-07-17 吴伟华 A kind of preparation method of labour protection cold cream
CN108721186A (en) * 2018-08-02 2018-11-02 江西登云健康美业互联有限公司 A kind of anti-ageing face cream and preparation method thereof
CN108721186B (en) * 2018-08-02 2021-04-20 江西登云健康美业互联有限公司 Anti-aging face cream and preparation method thereof
CN114177126A (en) * 2020-09-14 2022-03-15 广州壹美生物科技有限公司 Hibiscus makinoi youth reversed-age balancing cream
CN113413350A (en) * 2021-07-13 2021-09-21 广州芳利医药科技有限公司 Composition for improving female hormone level and preparation method and application thereof
CN116725927A (en) * 2023-08-09 2023-09-12 美出莱(杭州)化妆品有限责任公司 Spatial structure composition containing peony active ingredient and preparation method and application thereof
CN116725927B (en) * 2023-08-09 2023-11-17 美出莱(杭州)化妆品有限责任公司 Spatial structure composition containing peony active ingredient and preparation method and application thereof

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