CN1059095C - Medicine for treatment of infectious oral disease - Google Patents
Medicine for treatment of infectious oral disease Download PDFInfo
- Publication number
- CN1059095C CN1059095C CN95115926A CN95115926A CN1059095C CN 1059095 C CN1059095 C CN 1059095C CN 95115926 A CN95115926 A CN 95115926A CN 95115926 A CN95115926 A CN 95115926A CN 1059095 C CN1059095 C CN 1059095C
- Authority
- CN
- China
- Prior art keywords
- medicine
- treatment
- preparation
- periodontitis
- soak
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention belongs to a medicine for curing infective oral diseases, particularly to a Chinese herbal medicine preparation for curing oral diseases, such as gum tooth, periodontitis, pericoronitis, periodical periodontitis, etc. The preparation is prepared by the steps that four Chinese herbal medicines, such as alum, pomegranate rind, Chinese gall and licorice root are pulverized and mixed, and then the filter liquor of the soak liquor is placed in an ampoule bottle. The filter liquor is instilled or filled in afflicted parts after being dipped by a medicated thread so as to enalbe the filter liquor to take effect. The present invention has the characteristics of simple preparation method, convenient use, less medicine raw materials, short course of treatment, conspicuous curative effect, etc.
Description
The invention belongs to the Chinese herbal and crude drugs preparations of treatment oral pathology, is a kind of medicine that is particularly suitable for treating infectious oral diseases such as gingivitis, periodontitis, pericoronitis and periapical periodontitis.
The pathogenic bacterium of present many oral cavity infection diseases all are the mixed infection based on anaerobe, as the gingiva bacteroid is the main pathogenic bacterium of periodontitis, infection and bacteroides melanogenicus group that the acute and chronic periapical periodontitis is suffered from the root canal have substantial connection, in addition except that the antibacterial class cause of disease, result of study shows that gingivitis, periodontitis, the intraoral oral cavity of pericoronitis patient protozoon are that the infection rate of gums ameba and buccalis is apparently higher than the oral health person.At the above-mentioned cause of disease, clinical treatment periodontal disease, pericoronitis are used metronidazole (metronidazole) more, and the periapical periodontitis patient is used always formaldehyde cresol formocresol (FC) as the root canal disinfection agent.It is low that these Western medicine class preparations comprise that its improvement dosage form (as metronidazole controlled release medicine film and metronidazole rod etc.) all exists local drug concentration to some extent, curative effect is relatively poor and the course of treatment is long, the effect of paying of certain poison is arranged as FC root canal disinfection agent, though curative effect certainly, has stronger cytotoxicity and deficiencies such as zest, antigenicity.Utilize that the type of preparation of Chinese herbal medicine compatibility treatment oral disease is also more sees, but because the pathogenesis of oral disease is very complicated, often a kind of preparation is difficult to that above-mentioned four kinds of sufferers are all had significant curative effect, and its preparation technology is also more numerous and diverse.
The object of the present invention is to provide a kind of medicine for the treatment of infectious oral disease.This medicine is pressed certain weight ratio compatibility with four flavor Chinese herbal medicine such as Alumen, Galla Chinensis, Pericarpium Granati, Radix Glycyrrhizae, and after being ground into powder-mixed, soaks effective time in the distilled water of effective dose, is this medicinal liquid with getting its supernatant behind the soaked medical filtration.Medicinal liquid is contained in the ampoule shape flexible container with crooked syringe needle during use, by squeeze receptacle medicinal liquid is instiled in the affected part.Odontopathy illness such as gingivitis, periodontitis, pericoronitis, periapical periodontitis there is obvious curative effects, also is convenient to patient's medication voluntarily, to overcome the existing in prior technology deficiency.
Drug ratio of the present invention and preparation method are:
A kind of medicine for the treatment of infectious oral disease, by 1: 1.2-2.5: 1.2-5: the weight ratio of 0.6-1.5 is got Alumen, Galla Chinensis, Pericarpium Granati, Radix Glycyrrhizae four flavor Chinese herbal medicine, a certain amount of distilled water and a small amount of ethanol are added in the powdered mixing of pulverize separately back, soak after the effective time and to preserve the medicinal liquid that is this medicine with getting the sealing of packing in the container after the sterilization of its supernatant behind the soaked medical filtration; Medicinal liquid can be contained into directly pushing drop in the soft ampoule formula container with crooked syringe needle in the affected part during use, and the cotton sth. made by twisting that maybe will be soaked with medicinal liquid is inserted in the trouble root canal, with zinc oxide cement capping certain hour.
Preparing required each the Chinese herbal medicine weight of this medicinal liquid is:
The weight of four of required interpolation flavor herbal powders is respectively in every 100ml distilled water: Alumen 4-5 gram, and Pericarpium Granati 5-20 gram, Galla Chinensis 5-10 gram, Radix Glycyrrhizae 3-6 gram, soak time is 15-25 days.
Usage, the consumption of medicinal liquid are:
The capacity that instils with ampoule formula medicine bottle is 5-10ml, and crooked syringe needle is installed during use, and every day 1-2 time is at an amount of medicinal liquid of affected part drop.
When using this medicinal liquid treatment periapical periodontitis, soak full medicinal liquid with cotton sth. made by twisting and be placed in the trouble root canal, with zinc oxide cement capping further consultation after 3-4 days.
Embodiments of the invention are as follows:
1, get Alumen 4 gram, Pericarpium Granati 5 grams, Galla Chinensis 5 grams, Radix Glycyrrhizae 3 gram pulverize separately powdereds and mix the back and add 100ml distilled water and micro-ethanol, soaked 20 days, the supernatant after the filtration soak is this medicinal liquid.
2, get Alumen 4 grams, Pericarpium Granati 10 grams, Galla Chinensis 10 grams, Radix Glycyrrhizae 6 grams, add distillation water yield 100ml, soak time is 25 days, and all the other preparation methoies as described above.
3, get Alumen 5 grams, Pericarpium Granati 20 grams, Galla Chinensis 10 grams, Radix Glycyrrhizae 6 grams, adding the distillation water yield is 100ml, and soak time is 25 days, and all the other preparation methoies as described above.
Because oral cavity infection illness majorities such as periodontal disease, pericoronitis have red swelling of gingiva, hemorrhage, dense, the clinical characters such as the gingival sulcus liquid measure increases of overflowing, should select the pharmaceutical formulation of removing dampness, hemostasis, removing toxic substances and promoting subsidence of swelling by theory of Chinese medical science for use, and be the mixed infection cause of disease based on anaerobe at periodontitis, pericoronitis and periapical periodontitis, should screen particularly has inhibiting medicine to carry out assembly to anaerobe to various bacteria.Alumen has removing toxic substances and promoting subsidence of swelling in the selected prescription, removing dampness hemostatic effect, particularly Alumen have high susceptibility to oral cavity aerobe and anaerobe, and obvious anti-trichomonal effect is arranged.It is wet mashed that gallic astringing to arrest bleeding effect can be treated pus, and the Galla Chinensis soak also has obvious inhibition and killing action to staphylococcus aureus, streptococcus, bacillus pyocyaneus etc. in addition.The Pericarpium Granati soak has the astringing to arrest bleeding insecticidal action, remove effective to amebic dysentery, also to staphylococcus aureus, mycetozoan and collude Leptospiral etc. inhibitory action is all arranged.In a word, because Pericarpium Granati, Galla Chinensis all contain a large amount of tannins, Alumen is alkaline potassium aluminum sulfate, so this three distinguish the flavor of astriction of medicine is stronger, can make protein coagulating, little vasoconstriction, blood coagulation and stopping blooding.Radix Glycyrrhizae has detoxifcation, is in harmonious proportion property of medicine effect in addition, and glycyrrhizin wherein has the glucocorticoid effect, and enoxolone has antiinflammatory action, has certain antibiotic, a protozoacide effect external.The synergistic result of the mutual compatibility of soak of this four flavors Chinese herbal medicine observes according to a large amount of clinical cases and shows that for the mixed infection oral pathology based on anaerobe good efficacy is all arranged.
The substantive distinguishing features that the present invention has and obtained remarkable technological progress are:
This Chinese medicine preparation only with four the flavor Chinese herbal medicines the immersion filtered fluid as the treatment infectious oral cavity The medicine of disease has special efficacy to gingivitis, periodontitis, pericoronitis and periapicitis. Can with Its soup is packaged in the plastic material bottle of 10ml capacity (similar eye drop container), Install crooked syringe needle additional at its neck mouth place during use, extrusion bottle drips profit in the sufferer place, and is flat All three to four symptoms of medication can obviously be improved or substantially disappear. This soup is for four kinds The pathogenesis of infectious oral disease, and according to the property of medicine etc. to adopt four flavor Chinese herbal medicines Physiological pathology is analyzed the Chinese herbal and crude drugs preparations of reasonable preparation, and it is less to have used drug kinds, preparation The characteristics such as method is simple and easy to use, and short treating period is evident in efficacy.
Claims (2)
1, a kind of medicine for the treatment of infectious oral disease, the weight ratio that it is characterized in that each crude drug is: Alumen: Galla Chinensis: Pericarpium Granati: Radix Glycyrrhizae=1: 1.2-2.5: 1.2-5: 0.6-1.5, its method for making is: each medicine pulverize separately is powdered, the ratio that restrains corresponding 100ml distilled water in Alumen 4-5 gram, Pericarpium Granati 5-20 gram, Galla Chinensis 5-10, Radix Glycyrrhizae 3-6 adds distilled water, soak the effective time after-filtration and get supernatant, sealing is preserved and is this medicine in the container after the sterilization of packing into
2, medicine according to claim 1, it is characterized by soak time is 15-25 days, can also add a small amount of ethanol in immersion process
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN95115926A CN1059095C (en) | 1995-09-21 | 1995-09-21 | Medicine for treatment of infectious oral disease |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN95115926A CN1059095C (en) | 1995-09-21 | 1995-09-21 | Medicine for treatment of infectious oral disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1145793A CN1145793A (en) | 1997-03-26 |
| CN1059095C true CN1059095C (en) | 2000-12-06 |
Family
ID=5080695
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN95115926A Expired - Fee Related CN1059095C (en) | 1995-09-21 | 1995-09-21 | Medicine for treatment of infectious oral disease |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1059095C (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1330337C (en) * | 2004-08-30 | 2007-08-08 | 纪险峰 | Pure Chinese medicine for treating protrasion of lumbar intervertebral disc and osteoporosis and preparation method |
| CN102940595A (en) * | 2012-12-04 | 2013-02-27 | 中国科学院新疆理化技术研究所 | Mouthwash with functions of antibiosis, antiphlogosis and deodorization, and preparation method and use thereof |
| CN107412131B (en) * | 2017-08-14 | 2020-09-01 | 武汉美一棠口腔有限公司 | Oral care liquid |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1098299A (en) * | 1993-08-04 | 1995-02-08 | 赵世平 | The sweet cool Kouchuang powder for curing aphthosis and the compound method thereof that are used for recurrent aphtha and all kinds of aphthas |
-
1995
- 1995-09-21 CN CN95115926A patent/CN1059095C/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1098299A (en) * | 1993-08-04 | 1995-02-08 | 赵世平 | The sweet cool Kouchuang powder for curing aphthosis and the compound method thereof that are used for recurrent aphtha and all kinds of aphthas |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1145793A (en) | 1997-03-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN100420432C (en) | Gargle and its preparing process | |
| CN105310960B (en) | A kind of novel polysaccharide antimicrobial mouthwash and preparation method thereof | |
| CN101007088A (en) | A traditional Chinese medicine composition for treating periodontal diseases and its preparation method | |
| CN108420768A (en) | A kind of shield gum toothpaste of anti-inflammation hemostasia and preparation method thereof | |
| CN1059095C (en) | Medicine for treatment of infectious oral disease | |
| CN105326901B (en) | A kind of Chinese medicine composition treated and/or prevent mouth disease and preparation method thereof | |
| CN106974866A (en) | A kind of folium artemisiae argyi formula toothpaste and preparation method thereof | |
| CN103599182A (en) | Traditional Chinese medicine composition and preparation method thereof, and oral cavity cleaning and nursing product and preparation method thereof | |
| CN1311840C (en) | Quick-acting liquid preparation for toothache | |
| CN101744871B (en) | Propolis Chinese medicinal preparation for treating toothaches and preparation method thereof | |
| CN105213216B (en) | A kind of natural disaccharide antibacterial shield tooth gargle and preparation method thereof | |
| CN102824511B (en) | Miao medicine used for oralcavity and preparation technology | |
| CN102552086B (en) | Tooth-fixing and pain-eliminating gargle | |
| CN103169808B (en) | A kind of Chinese medicine preparation treated cult poison and invade the acute alveolar bone osteomyelitis disease of marrow type | |
| CN1079031C (en) | Chinese medicine composition for treating toothache | |
| CN1336169A (en) | Medicated toothpaste | |
| CN103933274A (en) | Traditional Chinese medicine preparation for treating periodontitis | |
| CN1035037C (en) | Tooth strengthening agent (Guchiling) | |
| CN107320385A (en) | A kind of compound Chinese herb children's toothpaste | |
| CN106474270A (en) | A kind of oral cavity cleaning water | |
| CN1219529C (en) | Medicine for treating toothache | |
| CN1164283C (en) | Pulmonotis treating Chinese medicine powder | |
| CN1322533A (en) | Chinese medicine composition preparation for treating alveolysis | |
| CN104800284A (en) | Miao medicine for treating stomatitis | |
| CN101081200A (en) | Novel oral health collutory |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |