CN105907629A - Cell collection scraping knife - Google Patents
Cell collection scraping knife Download PDFInfo
- Publication number
- CN105907629A CN105907629A CN201610500993.8A CN201610500993A CN105907629A CN 105907629 A CN105907629 A CN 105907629A CN 201610500993 A CN201610500993 A CN 201610500993A CN 105907629 A CN105907629 A CN 105907629A
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- Prior art keywords
- main body
- body bar
- bar
- base
- operating
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/04—Cell isolation or sorting
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Cleaning In General (AREA)
Abstract
The invention belongs to the field of biological medical equipment and relates to a cell collection scraping knife. The cell collection scraping knife comprises a main body rod and a scraping knife structure arranged at the front end of the main body rod, wherein the scraping knife structure comprises a base hinged to the main body rod and a scraping sheet arranged at the front end of the base; the main body rod is internally provided with an operation channel; the operation channel is internally provided with two operation ropes; one end of each of the two operation ropes is fixed with the two sides of the base; and the other ends of the operation ropes stretch out from the operation channel and are fixed with a manipulation part outside of the operation channel. The cell collection scraping knife can be used for collecting cells at any angle so that the cell collection scraping knife has a wide application range and the angle adjustment operation is convenient; and almost collected cells are centralized on the collection scraping sheet and the collection effect is relatively good.
Description
Technical field
The invention belongs to biomedical devices field, relate to a kind of cell and collect scraper.
Background technology
A requisite process in the inspection of cell culture technology a lot of biomedicine experiment, culture bottle is generally used to cultivate, when harvesting, needing by the assistive device of such as scraper etc, such as Patent No. CN204111739 is in the special cell scraper of medical science a kind of disclosed in 21 days January in 2015, including blade, harvesting when cell is cultivated, described blade includes that knife rest and the edge of a knife, the described edge of a knife are yi word pattern, and the bottom of described knife rest is fixed on the top of the described edge of a knife;Handle of a knife, described handle of a knife is shaft-like, and the front end of described handle of a knife and described knife rest are flexibly connected.The present invention is simple, convenient, it is easy to operation, it is critical that, the present invention is harvesting when cell is cultivated, little to cell damage, it is possible to all surface of exposing cell growth as far as possible.But time actually used, there is also some defects, such as: inconvenient during angular adjustment, affect collecting effect;The excursion of angle is limited etc..
Summary of the invention
It is an object of the invention to a kind of cell and collect scraper, not only angular adjustment is convenient, moreover it is possible to comprehensive adapt to the change of any angle without dead angle collection, and collecting effect is good, easy to operate.
In order to achieve the above object, the present invention adopts the following technical scheme that: cell collects scraper, including main body bar and the blade construction being arranged on described main body bar front end, described blade construction includes the base hinged with described main body bar and is arranged on the scraping blade of described pan frontward end, it is provided with operating walk way in described main body bar, two operating ropes it are provided with in described operating walk way, both sides with described base respectively, one end of two described operating ropes are fixed, and the other end of described operating rope stretches out from described operating walk way to be fixed with the manipulation part being arranged on described operating walk way.
As preferably, it is provided with bar in operation in described main body bar, in described operation, between bar and described main body bar, forms described operating walk way, fix between bar with described base in described operation and be connected, can relatively rotate between described main body bar and described base.
As preferably, the front end of described main body bar arranges the connecting portion with spherical inner groovy, described base arranges the auxiliary section with spheroid, is connected by described spherical inner groovy and described spheroid between described main body bar and described base.
As preferably, being provided with two operating grooves being oppositely arranged in described operating walk way on the inwall of described main body bar, described operating rope is arranged in described operating groove.
As preferably, the middle part of described main body bar has bellows segment.
As preferably, the 1/4-1/2 of a diameter of described main body bar internal diameter of bar in described operation.
As preferably, described scraping blade includes the basilar part being connected with described base and is positioned at the receipts of described basilar part front end and scrapes portion, and described receipts scrape the thickness thickness less than described basilar part in portion.
As preferably, the described receipts portion of scraping includes that the receipts of front end are scraped end, are positioned at described receipts and scrape the guide portion at rear, end and be positioned at the collection portion at described guide portion rear.
As preferably, the width of described guide portion scrapes the width of end more than described receipts.
As preferably, described guide portion is provided with the guiding groove arranged along guide portion width, and described collection portion is provided perpendicular to guiding groove the collecting tank communicated with described guiding groove.
By implementing technique scheme, the present invention has a following beneficial effect: the present invention can be for the collection of cell in the case of arbitrarily angled, and range is wide, and angular adjustment is easy to operate, and the cell collected can be largely focused on collection scraping blade, and collecting effect is more preferable.
Accompanying drawing explanation
Accompanying drawing 1 is the structural representation of one embodiment of the invention;
Accompanying drawing 2 is the sectional view of accompanying drawing 1;
Accompanying drawing 3 is blade construction schematic diagram in one embodiment of the invention.
Detailed description of the invention
Below in conjunction with the accompanying drawings and specific embodiment, the present invention is described in further detail.
Embodiment 1:
As shown in accompanying drawing 1,2, a kind of cell collects scraper, main body bar 10 and the blade construction of main body bar 10 front end including interior sky, wherein, blade construction includes base 20 and is arranged on the scraping blade 21 of base 20 front end, and described base includes the auxiliary section 201 that is connected with main body bar 10 and the main part hinged with auxiliary section 201.Bar 60 in operation it is provided with in main body bar 10, operating walk way 30 is formed between bar 60 in main body bar 10 and operation, two operating grooves being oppositely arranged 102 it are provided with on main body bar 10 inwall in operating walk way 30, two operating ropes 40 it are provided with in operating groove 102, both sides with the main part of base 20 respectively, one end of two described operating ropes 40 are fixed, the other end stretches out from described operating walk way 30 to be fixed with the manipulation part 50 being arranged on described operating walk way 30, control operating rope 40 by manipulation part 50 and drive main part, realize the change of angle between scraping blade 21 and main body bar 10, easy to operate.
Embodiment 2:
A kind of cell collects scraper, including main body bar 10 and the blade construction being arranged on main body bar 1 front end, blade construction is as shown in Figure 3, including the base 20 being connected with main body bar 10 and the scraping blade 21 being arranged on base 20 front end, scraping blade 21 includes the basilar part 211 being connected with base 20 and is positioned at the receipts of basilar part 211 front end and scrapes portion 212, receives the thickness scraping portion 212 less than the thickness of basilar part 211;Wherein, receipts are scraped portion 212 and are included that again the receipts of front end are scraped end 2121, received and scrape the guide portion 2122 at rear, end 2121 and be positioned at the collection portion 2123 at guide portion 2122 rear, and the width of guide portion 2122 scrapes the width of end 2121 more than described receipts;Guide portion 2122 is provided with the guiding groove 2124 arranged along guide portion 2122 width, described collection portion 2123 is provided with the collecting tank 2125 vertical with guiding groove 2124, and communicate between guiding groove 2124 with collecting tank 2125, because cell is mainly led into collecting tank 2125 by guiding groove 2124, and after cell arrives collecting tank 2125, the most all it is deposited in collecting tank 2125, no longer back into base 20.
Described base includes the auxiliary section 201 that is connected with main body bar 10 and the main part hinged with auxiliary section 201.Bar 60 in operation it is provided with in main body bar 10, operating walk way 30 is formed between bar 60 in main body bar 10 and operation, two operating ropes 40 it are provided with in operating walk way 30, both sides with the main part of base 20 respectively, one end of two described operating ropes 40 are fixed, the other end stretches out from described operating walk way 30 to be fixed with the manipulation part 50 being arranged on described operating walk way 30, control operating rope 40 by manipulation part 50 and drive main part, it is achieved the change of angle between scraping blade 21 and main body bar 10, easy to operate.
The front end of main body bar 10 arranges connecting portion 101, for spherical inner groovy, the auxiliary section 201 of base 20 has a spheroid structure, it is connected by the connecting portion 101 of ball recess and the auxiliary section 201 of spheroid between main body bar 10 and base 20, under this connected mode, can relatively rotate between main body bar 10 and base 20, in operation, the end of bar 60 is connected with spheroid, base 20 is driven to rotate relative to main body bar 10, to change the angle of scraping blade 21 by bar 60 in operation.In conjunction with hinged between main part and the auxiliary section 201 of above-mentioned base 20, on the one hand can be by angle between scraping blade 21 and auxiliary section 201 in hinged change base body portion, on the other hand in can utilizing operation, bar 60 changes the angle between base 20 and main body bar 10, realize double angle to change, change wider.The 1/4-1/2 of a diameter of main body bar 10 internal diameter of bar 60 in operation, the present embodiment is 1/3, and, the middle part of main body bar 10 has bellows segment, this design, main body bar 10 can be carried out angle and curved, realize the adaptation of angle, when in operation, the diameter of bar 60 is at the 1/4-1/2 of main body bar 10 internal diameter, the angular adjustment operated between regulation and base body portion and auxiliary section of bar 60 in the angle change compounding practice that can bend to, the angle of scraper can be transferred to any angle, no matter under what angle, all cell can be collected.
Claims (10)
1. cell collects scraper, including main body bar (10) and the blade construction that is arranged on described main body bar (10) front end, described blade construction includes base (20) and is arranged on the scraping blade (21) of described base (20) front end, it is characterized in that, described base includes the auxiliary section (201) that is connected with described main body bar (10) and the main part hinged with described auxiliary section (201), it is provided with operating walk way (30) in described main body bar (10), two operating ropes (40) it are provided with in described operating walk way (30), both sides with described base (20) respectively, one end of two described operating ropes (40) are fixed, the other end of described operating rope (40) stretches out from described operating walk way (30) to be fixed with the manipulation part (50) being arranged on described operating walk way (30).
The most according to claim 1, cell collects scraper, it is characterized in that, bar (60) in operation it is provided with in described main body bar (10), described operating walk way (30) is formed between bar (60) and described main body bar (10) in described operation, fix between bar (60) with described base (20) in described operation and be connected, can relatively rotate between described main body bar (10) and described base (20).
The most according to claim 2, cell collects scraper, it is characterized in that, the front end of described main body bar (10) arranges the connecting portion (101) with spherical inner groovy, there is on described base (20) auxiliary section (201) structure of spheroid, be connected by described spherical inner groovy and described spheroid between described main body bar (10) and described base (20).
The most according to claim 2, cell collects scraper, it is characterized in that, being provided with two operating grooves being oppositely arranged (102) in described operating walk way (30) on the inwall of described main body bar (10), described operating rope (40) is arranged in described operating groove (102).
The most according to claim 3, cell collects scraper, it is characterised in that the middle part of described main body bar (10) has bellows segment.
The most according to claim 5, cell collects scraper, it is characterised in that the 1/4-1/2 of a diameter of described main body bar (10) internal diameter of bar (60) in described operation.
The most according to claim 1, cell collects scraper, it is characterized in that, described scraping blade (21) includes that the basilar part (211) being connected with described base (20) and the receipts being positioned at described basilar part (211) front end scrape portion (212), and described receipts scrape the thickness thickness less than described basilar part (211) in portion (212).
The most according to claim 7, cell collects scraper, it is characterized in that, described receipts are scraped portion (212) and are included that the receipts of front end are scraped end (2121), are positioned at described receipts and scrape the guide portion (2122) at end (2121) rear and be positioned at the collection portion (2123) at described guide portion (2122) rear.
The most according to claim 8, cell collects scraper, it is characterised in that the width of described guide portion (2122) scrapes the width of end (2121) more than described receipts.
The most according to claim 8 or claim 9, cell collects scraper, it is characterized in that, described guide portion (2122) is provided with the guiding groove (2124) arranged along guide portion (2122) width, and described collection portion (2123) is provided perpendicular to guiding groove (2124) the collecting tank (2125) communicated with described guiding groove (2124).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201610500993.8A CN105907629B (en) | 2016-06-30 | 2016-06-30 | Cell collects scraper |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN201610500993.8A CN105907629B (en) | 2016-06-30 | 2016-06-30 | Cell collects scraper |
Publications (2)
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CN105907629A true CN105907629A (en) | 2016-08-31 |
CN105907629B CN105907629B (en) | 2018-03-23 |
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CN201610500993.8A Active CN105907629B (en) | 2016-06-30 | 2016-06-30 | Cell collects scraper |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112239712A (en) * | 2020-09-18 | 2021-01-19 | 宁波海关技术中心 | Scraper blade ware that uses when supplying cell adherence |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6194199B1 (en) * | 1998-09-17 | 2001-02-27 | Michael Hoffman | Cell scraper device having blade on handles with pivotal joints |
CN102839114A (en) * | 2012-09-26 | 2012-12-26 | 无锡耐思生物科技有限公司 | Cell scraper structure |
CN103725594A (en) * | 2013-12-25 | 2014-04-16 | 广州洁特生物过滤制品有限公司 | Cell scraper |
CN204111739U (en) * | 2014-09-22 | 2015-01-21 | 浙江拱东医疗科技有限公司 | The special cell scraper of medical science |
CN205275592U (en) * | 2015-11-26 | 2016-06-01 | 华东师范大学 | Cell scraper |
CN205741027U (en) * | 2016-06-30 | 2016-11-30 | 浙江硕华生命科学研究股份有限公司 | Cell collects scraper |
-
2016
- 2016-06-30 CN CN201610500993.8A patent/CN105907629B/en active Active
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6194199B1 (en) * | 1998-09-17 | 2001-02-27 | Michael Hoffman | Cell scraper device having blade on handles with pivotal joints |
CN102839114A (en) * | 2012-09-26 | 2012-12-26 | 无锡耐思生物科技有限公司 | Cell scraper structure |
CN103725594A (en) * | 2013-12-25 | 2014-04-16 | 广州洁特生物过滤制品有限公司 | Cell scraper |
CN204111739U (en) * | 2014-09-22 | 2015-01-21 | 浙江拱东医疗科技有限公司 | The special cell scraper of medical science |
CN205275592U (en) * | 2015-11-26 | 2016-06-01 | 华东师范大学 | Cell scraper |
CN205741027U (en) * | 2016-06-30 | 2016-11-30 | 浙江硕华生命科学研究股份有限公司 | Cell collects scraper |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112239712A (en) * | 2020-09-18 | 2021-01-19 | 宁波海关技术中心 | Scraper blade ware that uses when supplying cell adherence |
CN112239712B (en) * | 2020-09-18 | 2023-07-21 | 宁波海关技术中心 | Scraper for cell adhesion |
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CN105907629B (en) | 2018-03-23 |
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