CN105907629B - Cell collects scraper - Google Patents

Cell collects scraper Download PDF

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Publication number
CN105907629B
CN105907629B CN201610500993.8A CN201610500993A CN105907629B CN 105907629 B CN105907629 B CN 105907629B CN 201610500993 A CN201610500993 A CN 201610500993A CN 105907629 B CN105907629 B CN 105907629B
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CN
China
Prior art keywords
main body
body bar
operating
base
bar
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Active
Application number
CN201610500993.8A
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Chinese (zh)
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CN105907629A (en
Inventor
蒋峥嵘
谢小良
孙晓晓
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zhejiang Sorfa Life Science Research Co Ltd
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Zhejiang Sorfa Life Science Research Co Ltd
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Priority to CN201610500993.8A priority Critical patent/CN105907629B/en
Publication of CN105907629A publication Critical patent/CN105907629A/en
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/04Cell isolation or sorting
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus

Abstract

The invention belongs to biomedical devices field, it is related to a kind of cell and collects scraper, including main body bar and the blade construction for being arranged on the main body bar front end, the blade construction includes the base being hinged with the main body bar and the scraping blade for being arranged on the pan frontward end, operating walk way is provided with the main body bar, two operating ropes are provided with the operating walk way, both sides of the one end of two operating ropes respectively with the base are fixed, and the other end of the operating rope stretches out from the operating walk way to be fixed with the manipulation part being arranged on outside the operating walk way.The present invention can be directed to the collection of cell in the case of any angle, and use range is wide, and angular adjustment is easy to operate, and the cell being collected into can be largely focused on and collect on scraping blade, and collecting effect is more preferable.

Description

Cell collects scraper
Technical field
The invention belongs to biomedical devices field, is related to a kind of cell and collects scraper.
Background technology
An essential process during many biomedicine experiments of cell culture technology are examined, generally use blake bottle enter Row culture, in harvesting, it is necessary to by such as scraper etc assistive device, such as Patent No. CN204111739 in A kind of special cell scraper of medical science disclosed in 21 days January in 2015, including:Blade, harvesting during for cell culture are described Blade includes knife rest and the edge of a knife, and the edge of a knife is in yi word pattern, and the bottom of the knife rest is fixed on the top of the edge of a knife;Knife Handle, the handle of a knife is in shaft-like, the front end of the handle of a knife and knife rest flexible connection.The present invention is simply, conveniently, easily operated, It is essential that the present invention be used for harvesting during cell culture, it is small to cell damage, and can as far as possible exposing cell grow All surface.But when actually using, there is also some defects, such as:Inconvenient during angular adjustment, influence collecting effect;Angle Excursion it is limited etc..
The content of the invention
The purpose of the present invention is that a kind of cell collects scraper, and not only angular adjustment is convenient, moreover it is possible to comprehensive no dead angle is collected, The change of any angle is adapted to, and collecting effect is good, it is easy to operate.
In order to achieve the above object, the present invention adopts the following technical scheme that:Cell collects scraper, including main body bar and sets The blade construction in the main body bar front end is put, the blade construction includes the base being hinged with the main body bar and is arranged on institute The scraping blade of pan frontward end is stated, operating walk way is provided with the main body bar, is provided with two operating ropes in the operating walk way, two Both sides of the one end of operating rope described in root respectively with the base are fixed, and the other end of the operating rope is stretched from the operating walk way The manipulation part for going out and being arranged on outside the operating walk way is fixed.
Preferably, being provided with operation interior bar in the main body bar, formed between the operation interior bar and the main body bar The operating walk way, it is fixedly connected between the operation interior bar and the base, can phase between the main body bar and the base To rotating.
Preferably, the front end of the main body bar sets the connecting portion with spherical inner groovy, tool is set on the base There is the auxiliary section of orbicule, coordinated between the main body bar and the base by the spherical inner groovy and the orbicule and connected Connect.
Preferably, two operating grooves being oppositely arranged are provided with the operating walk way on the inwall of the main body bar, The operating rope is arranged in the operating groove.
Preferably, the middle part of the main body bar has bellows segment.
Preferably, the 1/4-1/2 of a diameter of main body bar internal diameter of the operation interior bar.
Preferably, the scraping blade includes the basal part being connected with the base and the receipts positioned at the basal part front end are scraped Portion, the thickness for receiving portion of scraping are less than the thickness of the basal part.
Preferably, receipts for receiving the portion of scraping including front end scrape end, the guide portion at end rear is scraped positioned at the receipts with And the collection portion positioned at the guide portion rear.
Preferably, the width of the guide portion is more than the width received and scrape end.
Preferably, the guide portion is provided with the guiding groove set along guide portion width, the collection portion is set The collecting tank for having perpendicular to guiding groove and being communicated with the guiding groove.
By implementing above-mentioned technical proposal, the present invention has following beneficial effect:The present invention can be directed to any angle In the case of cell collection, use range is wide, and angular adjustment is easy to operate, and the cell being collected into can be largely focused on receipts Collect on scraping blade, collecting effect is more preferable.
Brief description of the drawings
Accompanying drawing 1 is the structural representation of one embodiment of the invention;
Accompanying drawing 2 is the sectional view of accompanying drawing 1;
Accompanying drawing 3 is blade construction schematic diagram in one embodiment of the invention.
Embodiment
Below in conjunction with the accompanying drawings and specific embodiment, the present invention is described in further detail.
Embodiment 1:
As shown in accompanying drawing 1,2, a kind of cell collects scraper, including interior empty main body bar 10 and the scraper of the front end of main body bar 10 Structure, wherein, blade construction includes base 20 and is arranged on the scraping blade 21 of the front end of base 20, and the base includes and main body bar 10 The auxiliary section 201 of connection and the main part being hinged with auxiliary section 201.Operation interior bar 60, main body bar 10 are provided with main body bar 10 Operating walk way 30 is formed between operation interior bar 60, two is provided with operating walk way 30 on the inwall of main body bar 10 and is oppositely arranged Operating groove 102, is provided with two operating ropes 40 in operating groove 102, one end of two operating ropes 40 respectively with base 20 The both sides of main part are fixed, and the other end stretches out the manipulation part 50 with being arranged on outside the operating walk way 30 from the operating walk way 30 It is fixed, main part is driven by manipulating the control operation rope 40 of part 50, the change of angle between scraping blade 21 and main body bar 10 is realized, grasps Facilitate.
Embodiment 2:
A kind of cell collects scraper, including main body bar 10 and the blade construction for being arranged on the front end of main body bar 1, and blade construction is such as Shown in accompanying drawing 3, including the base 20 that is connected with main body bar 10 and the scraping blade 21 for being arranged on the front end of base 20, scraping blade 21 includes and bottom The basal part 211 of the connection of seat 20 and the receipts positioned at the front end of basal part 211 scrape portion 212, and the thickness that receipts scrape portion 212 is less than basal part 211 thickness;Wherein, the receipts for scraping portion 212 and including front end are received to scrape end 2121, receive the guide portion 2122 for scraping the rear of end 2121 And the collection portion 2123 positioned at the rear of guide portion 2122, the width of guide portion 2122 are more than the width received and scrape end 2121 Degree;Guide portion 2122 is provided with the guiding groove 2124 set along the width of guide portion 2122, and the collection portion 2123 is set There is the collecting tank 2125 vertical with guiding groove 2124, and communicated between guiding groove 2124 and collecting tank 2125, because guiding groove Cell is mainly led into collecting tank 2125 by 2124, and after cell reaches collecting tank 2125, it is therefore desirable to all it is deposited in receipts Collect groove 2125, no longer back into base 20.
The base includes the auxiliary section 201 being connected with main body bar 10 and the main part being hinged with auxiliary section 201.Main body bar Operation interior bar 60 is provided with 10, operating walk way 30 is formed between main body bar 10 and operation interior bar 60, is set in operating walk way 30 Have two operating ropes 40, the both sides of one end of two operating ropes 40 respectively with the main part of base 20 are fixed, the other end from The operating walk way 30 stretches out to be fixed with the manipulation part 50 being arranged on outside the operating walk way 30, by manipulating the control operation of part 50 Rope 40 drives main part, realizes the change of angle between scraping blade 21 and main body bar 10, easy to operate.
The front end of main body bar 10 sets connecting portion 101, is spherical inner groovy, and the auxiliary section 201 of base 20 is spherical with one Body structure, coordinated between main body bar 10 and base 20 by the connecting portion 101 of ball recess and the auxiliary section 201 of orbicule and connected Connect, under this connected mode, can be relatively rotated between main body bar 10 and base 20, the end and orbicule for operating interior bar 60 connect Connect, drive base 20 to be rotated relative to main body bar 10 by operation interior bar 60, to change the angle of scraping blade 21.With reference to above-mentioned base 20 It is hinged between main part and auxiliary section 201, on the one hand can changes scraping blade 21 and auxiliary section 201 in base body portion by be hinged Between angle, on the other hand can utilize and operate interior bar 60 and change angle between base 20 and main body bar 10, realize dual Angulation change, it is wider to change scope.The 1/4-1/2 of a diameter of internal diameter of main body bar 10 of operation interior bar 60, the present embodiment 1/3, Also, the middle part of main body bar 10 has bellows segment, the design, angle and curved can be carried out to main body bar 10, realize the suitable of angle Should, when operating the diameter of interior bar 60 in the 1/4-1/2 of the internal diameter of main body bar 10, the angle change compounding practice that can bend to The angle of scraper, can be transferred to any by the operation regulation of interior bar 60 and the angular adjustment between base body portion and auxiliary section What angle, no matter under angle, cell can be all collected.

Claims (1)

1. cell collects scraper, including main body bar(10)Be arranged on the main body bar(10)The blade construction of front end, it is described to scrape Knife structure includes base(20)Be arranged on the base(20)The scraping blade of front end(21), it is characterised in that the base includes With the main body bar(10)The auxiliary section of connection(201)With with the auxiliary section(201)Be hinged main part, the main body bar (10)Inside it is provided with operating walk way(30), the operating walk way(30)Inside it is provided with two operating ropes(40), two operations Rope(40)One end respectively with the base(20)Both sides fix, the operating rope(40)The other end from the operating walk way (30)Stretch out and be arranged on the operating walk way(30)Outer manipulation part(50)It is fixed;
The main body bar(10)Inside it is provided with operation interior bar(60), the operation interior bar(60)With the main body bar(10)Between shape Into the operating walk way(30), the operation interior bar(60)With the base(20)Between be fixedly connected, the main body bar(10) With the base(20)Between can relatively rotate;
The main body bar(10)Front end set with spherical inner groovy connecting portion(101), the base(20)Auxiliary section (201)The upper structure with orbicule, the main body bar(10)With the base(20)Between by the spherical inner groovy and The orbicule is connected;
The operating walk way(30)The interior main body bar(10)Inwall on be provided with two operating grooves being oppositely arranged(102), The operating rope(40)Installed in the operating groove(102)It is interior;
The main body bar(10)Middle part there is bellows segment;
The operation interior bar(60)A diameter of main body bar(10)The 1/4-1/2 of internal diameter;
The scraping blade(21)Including with the base(20)The basal part of connection(211)With positioned at the basal part(211)Front end Receipts scrape portion(212), the receipts scrape portion(212)Thickness be less than the basal part(211)Thickness;
The receipts scrape portion(212)Receipts including front end scrape end(2121), positioned at it is described receipts scrape end(2121)The guiding at rear Portion(2122)And positioned at the guide portion(2122)The collection portion at rear(2123);
The guide portion(2122)Width be more than it is described receipts scrape end(2121)Width;
The guide portion(2122)Provided with along guide portion(2122)The guiding groove that width is set(2124), the collection portion (2123)It is provided perpendicular to guiding groove(2124)And with the guiding groove(2124)The collecting tank communicated(2125).
CN201610500993.8A 2016-06-30 2016-06-30 Cell collects scraper Active CN105907629B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610500993.8A CN105907629B (en) 2016-06-30 2016-06-30 Cell collects scraper

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CN201610500993.8A CN105907629B (en) 2016-06-30 2016-06-30 Cell collects scraper

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CN105907629B true CN105907629B (en) 2018-03-23

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Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112239712B (en) * 2020-09-18 2023-07-21 宁波海关技术中心 Scraper for cell adhesion

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6194199B1 (en) * 1998-09-17 2001-02-27 Michael Hoffman Cell scraper device having blade on handles with pivotal joints
CN102839114A (en) * 2012-09-26 2012-12-26 无锡耐思生物科技有限公司 Cell scraper structure
CN103725594A (en) * 2013-12-25 2014-04-16 广州洁特生物过滤制品有限公司 Cell scraper
CN204111739U (en) * 2014-09-22 2015-01-21 浙江拱东医疗科技有限公司 The special cell scraper of medical science
CN205275592U (en) * 2015-11-26 2016-06-01 华东师范大学 Cell scraper
CN205741027U (en) * 2016-06-30 2016-11-30 浙江硕华生命科学研究股份有限公司 Cell collects scraper

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6194199B1 (en) * 1998-09-17 2001-02-27 Michael Hoffman Cell scraper device having blade on handles with pivotal joints
CN102839114A (en) * 2012-09-26 2012-12-26 无锡耐思生物科技有限公司 Cell scraper structure
CN103725594A (en) * 2013-12-25 2014-04-16 广州洁特生物过滤制品有限公司 Cell scraper
CN204111739U (en) * 2014-09-22 2015-01-21 浙江拱东医疗科技有限公司 The special cell scraper of medical science
CN205275592U (en) * 2015-11-26 2016-06-01 华东师范大学 Cell scraper
CN205741027U (en) * 2016-06-30 2016-11-30 浙江硕华生命科学研究股份有限公司 Cell collects scraper

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