CN105902993A - Combined medicament for treating female alopecia areata and preparation method thereof - Google Patents

Combined medicament for treating female alopecia areata and preparation method thereof Download PDF

Info

Publication number
CN105902993A
CN105902993A CN201610491981.3A CN201610491981A CN105902993A CN 105902993 A CN105902993 A CN 105902993A CN 201610491981 A CN201610491981 A CN 201610491981A CN 105902993 A CN105902993 A CN 105902993A
Authority
CN
China
Prior art keywords
parts
powder
alopecia areata
rascal
minute
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610491981.3A
Other languages
Chinese (zh)
Inventor
李肖
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201610491981.3A priority Critical patent/CN105902993A/en
Publication of CN105902993A publication Critical patent/CN105902993A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/28—Mercury; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605—Morus (mulberry)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/638—Ligustrum, e.g. Chinese privet
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738—Rosa (rose)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9068—Zingiber, e.g. garden ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/31—Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Inorganic Chemistry (AREA)
  • Insects & Arthropods (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a combined medicament for treating female alopecia areata, which is prepared from the following main raw materials in parts by weight: 5-10 parts of cutworms, 4-9 parts of ginseng, 10-20 parts of Chinese wax, 10-20 parts of prepared rehmannia root, 5-15 parts of aloe, 7-13 parts of ginger powder, 4-10 parts of dodders, 5-10 parts of green tangerine peel, 3-7 parts of glossy privet fruits, 2-4 parts of red pine, 5-10 parts of mulberry leaves, 3-8 parts of fleece-flower roots and 5-15 parts of rose hip seed oil. According to the combined medicament, the medicinal materials are easily available in medicine source and low in cost, and most of the selected medicinal materials are mild in property, so that the economical burden and physical burden of a user can not be increased after the combined medicament is used for a long time.

Description

A kind of combination medicament treating women alopecia areata and preparation method
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of combination medicament treating women alopecia areata and preparation side Method.
Background technology
On sensitive hair follicle, protona is combined with androgen receptor, this hormone receptor complex activated gene, makes Big terminal hair capsule gradates as miniaturization hair follicle.The various hairs that the length thickness that grows little hair follicle differs, these hairs are these The feature of one disease.At women patients with alopecia areata, this tiny hair ratio is relatively decentralized, but the most obvious at forehead and top scalp. Women generally retains a circle hair along the hairline of forehead.Tiny hair, sparse hairdo and disease time are relatively early supported this The diagnosis of one disease.Women serious alopecia areata situation women serious alopecia areata situation.The eumenorrhea of most of women patients with alopecia areatas, energy Normal pregnancy.Unless patient has a sings and symptoms of the Hyperandrogenisms such as crinosity, serious folliculitis, manlike feature, galactorrhea, one As need not do comprehensive hormone test.By measuring stosterone, dehydroepiandrosterone sulfate and prolactin total or free in serum Level judge that androgen is whether too much, getting rid of other by the method measuring serum thyroid hormones, iron and ferritin may Cause the reason of women alopecia areata.
Cause reason: the case of women alopecia areata heredity allergy about 10%～20% has family history.There is report enzygotic twins person same Time same position occur alopecia areata, also have report one 4 generation all have alopecia areata, it is believed that be genetic defect disease.Accumulate from clinic Data just find out there is the people of Atopic physique and easily occur together alopecia areata.In the child patient that U.S.'s statistics suffers from alopecia areata, 18% has Eczema or asthma, or both have concurrently；Adult's patients with alopecia areata accounts for 9%；The child patient ratio of whole alopecia is the highest, accounts for 23%.Japan The patients with alopecia areata of statistics has hereditary allergic constitution person to account for 10%, and Holland is then up to 52.4%.But Holland establishes heredity allergic constitution Foundation, be positive skin test and heredity family history person also include carrying out.Therefore various countries and area are to heredity The diagnostic criteria of allergic constitution is different, and data also cannot be carried out comparing.One alopecia areata and the correlative study table of human leucocyte antigen (HLA) Bright: HLA-A9 antigen frequency (16.67%) the calibration ordinary person (32.65%) of alopecia areata patient significantly reduces, prove from the angle of experiment It is to have certain hereditary intolerance factors to cause that the disease of alopecia areata is sent out.Women alopecia areata autoimmunity: the bald patient of class is with some self The ratio of immunity disease is higher than normal population.As accompanied thyroid disease, person accounts for 0～8%；Companion leucoderma person only accounts for 4%(normal person 1%).And research report about autoantibody differs in alopecia areata patient, with the presence of say, also have and do not find.Domestic letter One of river also exists the disorder of T cell network and body about prompting patients with alopecia areata in the research of T cell subgroup and β2-microglobulin Liquid immune disorder.Women alopecia areata other: 1, having some alopecia areatas is that the one of other diseases occurs together performance, such as hypothyroidism Or there are the several of alopecia areata in the patient such as hyperfunction, hypoparathyroidism, anaemia, lupus erythematosus, leucoderma, intestinal parasitism Rate is higher than normal person.It is the baldness which kind of reason causes as child, then needs to be investigated thoroughly.Cure.2, spot in Down syndrome Bald incidence increases, and is often whole alopecia or general alopecia.The existence of autoantibody showed increased in these patients.Still can not affirm alopecia areata Be exactly autoimmune disease, the autoimmune disease but it can occur together, the most effective etc. to cortin, prompting tend to from Body immunological theory.
In the Chinese medicine of existing treatment women alopecia areata, Authorization Notice No. CN 103565752 B(application number 201310491268.5) patent document discloses a kind of alopecia areata micropill, it is characterised in that the bulk drug of described alopecia areata micropill For: glutinous rehmannia 108-148 weight portion, prepared rhizome of rehmannia 108-148 weight portion, prepared fleece flower root 108-148 weight portion, Radix Angelicae Sinensis 60-98 Weight portion, red sage root 60-98 weight portion, root of herbaceous peony 60-98 weight portion, fruit of Chinese magnoliavine 60-98 weight portion, notopterygium root 30-50 weight portion, Pawpaw 30-50 weight portion；Containing pharmaceutic adjuvant 10-1000 weight portion in described alopecia areata micropill.Authorization Notice No. CN 102908429 B(application numbers 201210368556.7) patent document disclose a kind of Chinese medicine treating alopecia areata, its feature exists In: the weight proportion of its each raw material components is: pine needle 110-130, red ginseng 13-17, Psoralea corylifolia 13-17, safflower 13-17, leaflet Poplar 3-7, Rose Mallow Root 1-5.
As can be seen here, Chinese medicine occupies very important status in terms for the treatment of women alopecia areata, but in patent document, prescription Single, therapeutic domain is single, and effect is unsatisfactory, does not most importantly have the medicine of special for treating women alopecia areata, adds wound The psychological burden of person, and medical expense is high, adds the financial burden of patient.
Summary of the invention
For the deficiencies in the prior art, an object of the present invention is to provide the combination medicament for the treatment of women alopecia areata, this Invention medicinal material medicine source is easy to get, and with low cost, selected medicinal material mostly is the thing of mild in medicine property sum, and Long-Time Service also will not increase to user Burden in economy and health.
Another object of the present invention is just to provide the preparation method of combinations thereof medicament.
The technical scheme is that
The combination medicament for the treatment of women alopecia areata, takes off and states the primary raw material of weight proportion and be prepared from: cutworm 5-10 part, ginseng 4- 9 parts, insect wax 10-20 part, cultivated land 10-20 part, aloe 5-15 part, ginger powder 7-13 part, seed of Chinese dodder 4-10 part, rascal 5-10 Part, fruit of glossy privet 3-7 part, rouge and powder 2-4 part, mulberry leaf 5-10 part, fleece-flower root 3-8 part, rose hip oil 5-15 part.
The combination medicament for the treatment of women alopecia areata, preferred scheme is, takes off and states the primary raw material of weight proportion and be prepared from: Cutworm 6-9 part, ginseng 5-8 part, insect wax 13-18 part, cultivated land 13-18 part, aloe 8-13 part, ginger powder 9-11 part, the seed of Chinese dodder 6-8 part, rascal 6-9 part, fruit of glossy privet 4-6 part, rouge and powder 2.5-3.5 part, mulberry leaf 6-9 part, fleece-flower root 4-7 part, rose hip oil 8-13 Part.
The combination medicament for the treatment of women alopecia areata, the scheme being more highly preferred to is, takes off and states the primary raw material of weight proportion and prepare Form: cutworm 7.5 parts, ginseng 6.5 parts, insect wax 15 parts, 15 parts of cultivated land, aloe 10 parts, ginger powder 10 parts, the seed of Chinese dodder 7 parts, blue or green Skin 7.5 parts, the fruit of glossy privet 5 parts, 3 parts of rouge and powder, 8 parts of mulberry leaf, the fleece-flower root 5.5 parts, rose hip oil 10 parts.
The preparation method of combinations thereof medicament, step is as follows:
(1) aloe brush is cleaned down, remove thorn, then skin upper and lower for Chinese aloe leaf is also removed, rinse gel with water, will Gel is put in juice extractor 2-6 minute (preferably 4 minutes) of squeezing, filters off residue, obtains asparagus juice stand-by；
(2) insect wax, ginger powder and rouge and powder are gone the removal of impurity, tight with fresh lotus leaf parcel, it is placed on steaming tray and steams 20-40 Minute, take out dry in the air cool, by step (1) gained asparagus juice and rose hip oil together with the insect wax steamed, ginger powder and rouge and powder Mixing, constantly stir with waddy, the high-temperature sterilization 10-30 second, bottle medicine is smeared in external application；
(3) repeatedly stir-frying cutworm, cultivated land and the seed of Chinese dodder to crisp, grinding to form smalls, to cross 80-120 mesh sieve stand-by；
(4) ginseng, the fruit of glossy privet, mulberry leaf and the fleece-flower root are together placed in transparent container, add the warm water of 30-40 DEG C, clean Totally, chopping, with yellow rice wine, the bulk drug of chopping to be mixed thoroughly, be placed in tinfoil, upper baking box is baked 3-7 minute, takes out, and the 10-30 that dries in the air divides Clock, is laid on clean tile, and little fire dries 3-8 minute slowly, dries in the air to crisp, grinds to form smalls stand-by；
(5) being placed in marmite by rascal, add the clear water of rascal weight 4-10 times, big fire is boiled, and turns slow fire boiling 18-28 minute (preferably turning slow fire boiling 23 minutes), filters, and filtrate is stand-by；
(6) step (3) and (4) gained smalls are mixed, add in step (5) gained filtrate, be placed on electromagnetic oven heating While stirring, after mixing thoroughly completely, add dextrin, after dextrin melts completely, obtain mixed liquor cross 180-220 mesh screen pack, filtrate It it is oral liquid medicine.
The preparation method of combinations thereof medicament, step (2) is tight with fresh lotus leaf parcel, is placed on steaming tray and steams 25- 35 minutes (preferably, tight with fresh lotus leaf parcel, to be placed on steaming tray and steam 30 minutes).
The preparation method of combinations thereof medicament, step (3) grinds to form smalls and crosses stand-by (preferably, the grinding of 90-110 mesh sieve Smalls is become to cross 100 mesh sieves stand-by).
The preparation method of combinations thereof medicament, the consumption of step (4) yellow rice wine is to mix 0.3-0.7 times of bulk drug (preferably , the consumption of yellow rice wine is 0.4-0.6 times of mixing bulk drug, and more preferably, the consumption of yellow rice wine is the 0.5 of mixing bulk drug Times).
The preparation method of combinations thereof medicament, step (4) is dried in the air 15-25 minute, is laid on clean tile, and little fire dries slowly 4-7 minute (preferably, dry in the air 20 minutes, be laid on clean tile, little fire dries 5 minutes slowly).
The preparation method of combinations thereof medicament, step (5) adds the clear water of rascal weight 6-8 times and (preferably, adds rascal The clear water that weight is 7 times).
The preparation method of combinations thereof medicament, step (6) obtains mixed liquor after dextrin melts completely and crosses the filtration of 190-210 mesh Net (preferably obtains mixed liquor after dextrin melts completely and crosses 200 mesh screen packs).
The pharmacological effect of each bulk drug is respectively as follows:
Cutworm: for the stem tuber of Labiatae betony cutworm Stachys geobombycis C. Y. Wu.Be distributed in Zhejiang, The ground such as Fujian, Hunan, Jiangxi, Guangdong and Guangxi.There is kidney-nourishing moistening lung, nourishing yin and supplementing blood, effect of clearing heat and relieving fidgetness.It is usually used in lung knot Core is coughed, and the deficiency syndrome of the lung is panted, and spits blood, night sweat, anaemia, infantile malnutrition.
Ginseng: the superfine product of " kings of hundred grass " " enriching yin is mended raw, strengthens the body resistance to consolidate the constitution " is described as by ginseng from ancient times, containing multiple saponin and polysaccharide Constituents, leachate can slowly be absorbed by skin and without pessimal stimulation, energy skin expansion capillary, promote that skin blood follows Ring, increases skin-nourishing, the water and oil balance of regulation of skin, prevents skin dehydration, hardening, wrinkling, and the suppression of ginseng active material is black The reducing property of pigment, makes skin pure white smooth, can strengthen skin elasticity, makes cell obtain new life, is the superfine product improved looks. Ginseng is directly immersed in 50% glycerine, and after 10 days, face rubbed with the hands by glycerine, or ginseng is decocted into extract, every day toward face washing water a bit, with containing The glycerine of ginseng rubs face or ginseng water face-washing with the hands, and skin can be allowed the most moist.
Insect wax: have another name called Chinese wax, insect wax, haze tallow, vegetable wax, belongs to for a red-spotted lizard section wax insect secreted by the male worm of animal white wax insect Wax is refined to be formed.The property of medicine: this product, in irregular bulk, white or off-white color, has waxy gloss, and body is light, and matter is firmly and slightly crisp, taste Sweet, light, property is put down.Finding according to modern pharmacological research, this medical instrument has effect of hemostasis, myogenic, analgesic therapy, qi-restoratives, goes out for metal-inflicted wound Blood, hematuria, to have blood in stool, ulcer is burst for a long time and is not held back.
Cultivated land: Clinical practice has fresh, raw, ripe three kinds.All there is the merit of nourishing Yin and promoting production of body fluid, and control all cards of Yin and fluid deficiency.Fresh rehmannia root Sweetness and bitterness Great Cold, though the power of enriching yin is weak, but it is longer than clearing heat and cooling blood, purging intense heat relieving restlessness, it is used for blood-head heresy and contains, syndrome of yin deficiency and depletion of fluid；Raw The power that the sweet cold matter of (doing) glutinous rehmannia moistens cool blood is the most inferior but be longer than the moon of the kidney that nourishes heart, Gu Xuereyin injure fever due to yin deficiency person preferably it；Cultivated land Yellow sweet in flavor and warm in property, enter liver kidney and the special nourishing the blood and yin of merit, life essence-filling, marrow-benefitting, all kidney-KIN being deficients, marrow virtual loss person, all can use it.
Aloe: effect: purging intense heat；Removing toxic substances；Stagnation resolvation；Desinsection.Argument is red；Constipation；Gonorrhoea；Hematuria；Pediatric epilepsy scared；Infantile malnutrition due to digestive disturbances or intestinalparasites；Burn Scald；Women's amenorrhoea；Hemorrhoid；Scabies；Carbuncle furuncle poison；Traumatic injury.Bactericidal action, antiinflammatory action, moistening beautification function, stomach invigorating Under let out effect, the cardiac stimulant effect of invigorating blood circulation, immunity and palingenesis, immunity and antitumor action, detoxication, anti-aging effects, town Bitterly, sedation, anti-sunlight function.
Ginger powder: ginger powder nature and flavor: pungent, tepor, returns lung taste warp, ginger powder effect: inducing sweat and dispelling exogenous evils, warming middle energizer to arrest vomiting, Temperature lung cough-relieving, solving toxin of fish and crab, antidote poison.Ginger powder composition: containing pungent and fragrance ingredient.Piquancy component is waved for a kind of armaticity " zingerone " in hair oil fat.Wherein it is mainly ginger oil terpene, phellandium, CAM, gingerol, folium eucalypti olein, starch, mucus etc.. Ginger powder function: for the pungent stomachic tonic of armaticity, has the effects such as warm, excited, sweating, preventing or arresting vomiting, removing toxic substances, temperature lung cough-relieving, especially For fish crab poison, the drug poisoning such as the tuber of pinellia, rhizoma arisaematis has detoxication.Be applicable to catch cold, have a headache, phlegm and retained fluid, cough, stomach cold Vomiting;After suffering the invasion and attack wet, cold of ice and snow, water, suddenly drink it with ginger decoction, blood can be promoted, disperse cold-evil.
The seed of Chinese dodder: for the herb of the Convolvulaceae Hellweed seed of Chinese dodder.Composition: the seed of Chinese dodder contains alkaloid, anthraquinone, tonka-bean Element, flavones, glucoside, sterol, tannic acid, carbohydrate etc..Flavonoids has: Quercetin, astragalin, hyperin；Sterols has: cholesteric Alcohol, campesterol, cupreol, stigmasterol, β-amyrin.Also containing trace element such as strontium, molybdenum, calcium, magnesium, iron, manganese, zinc, copper Deng and several amino acids (free amino acid in seed and the total amino acid after hydrolysis are 5.3%, wherein essential amino acid Content accounts for 42.8%).The property of medicine: micro-pungent, sweet, flat, nontoxic.Function cures mainly: tonifying kidney and benefiting sperm, nourishes the liver to improve visual acuity.It is applicable to kidney deficiency and liver Waist knee muscles and bones is ached, legs and feet are weak and feeble, impotence and seminal emission, crazy talk, frequent urination, dripping urination, dizzy, blurring of vision, The diseases such as Hiccough and deaf and women carry down, habitual abortion.
Rascal: bitter, pungent, warm in nature.Gui Jing: return liver, courage, stomach warp.Function: have soothing the liver relieving stagnant Qi, effect that long-pendingization that disappear is stagnant.Main Control: for distending pain in the chest and hypochondrium, hernia pain, breast addiction, acute mastitis, stagnation of QI due to dyspepsia, abdominal distention.
The fruit of glossy privet: for the fruit of Oleaceae Ligustrum plant glossy privet.Composition: fruit contains triterpenes: oleanolic acid, acetyl is neat Pier tartaric acid, ursolic acid, acetyl ursolic acid；Phenolic glycoside class: p-hydroxyphenylethanol, Hydroxytyrosol, nuzhenide, olive is bitter Glycosides, glossy privet fruit glycosides, glossy privet acid, glossy privet thuja acid etc..The property of medicine: sweet, bitter, cold.Return liver, warp.Function cures mainly: tonify the liver and kidney, clearind deficient heat You, improving eyesight.Curing mainly Light-headedness, soreness and weakness of waist and knees, seminal emission, tinnitus, poliosis, osteopyrexia and fever, mesh is secretly failed to understand.
Rouge and powder: 1. antibacterial action: rouge and powder concentration 6 × l0 (-5) is in vitro to common suppurative bacterium, such as golden yellow grape Coccus, Escherichia coli have the strongest bactericidal action, its fungicidal effectiveness big more than 100 times than carbolic acid.But the compatibility due to rouge and powder And method for refining is incomplete same, therefore, drug ingedient, sterilizing power and curative effect also have difference.2. promotion Wound healing: art Rear infection of incisional wound, surface of a wound physiological saline cotton balls is wiped clearly totally, is sprinkled the rouge and powder of thin layer, covers with sterilized dressing.Treat purulence Liquid reduces, and during granulation new life, uses physiological saline sliver instead.Make to compare with the simple surgery cut infection case using rivanol sliver Relatively, wound heals in advance, and there were significant differences for curative effect.Ulcer furunculosis；Syphilitic chancre；Goiter and tumor scrofula；It is dark violet black that all dislike sore meat；Sore Mouth is hard；Slough does not goes；Sinus fistula；Pus drenches flood；Do not close up for a long time；Wet sore；Mange.
Mulberry leaf: these product are evacuated the most clearly, external enwergy dispelling wind and heat from the body, interior can clearing lung-heat, flat liver, improving eyesight, the conventional anemopyretic cold, scorching controlled The impariment of the lung, liver-yang hyperactivity and wind-heat or irascibility hot eyes flu, dry-heat impairing lung, liver-yang hyperactivity and wind-heat or irascibility red eye, swell pain, liver-yin The eyes of deficiency is dim-sighted.Additionally, again can cooling blood and hemostasis.
The fleece-flower root: primary efficacy: nourishing the blood and yin；Relax bowel；Preventing malaria；Dispel the wind；Removing toxic substances.Main deficiency of blood Light-headedness；Palpitaition； Insomnia；The soreness and weakness of waist and knees of the deficiency of liver-yin and kidney-yin；Poliosis；Tinnitus；Seminal emission；The dry constipation of intestines；Chronic malaria body is empty；Rubella itch；Sore carbuncle；Scrofula Scrofula；Hemorrhoid.
Rose hip oil: daily effect: deep layer Glycerin, offer nutrient, makes skin soft, soft, moistening, prevents ultraviolet Skin is damaged by line, skin whitening；Increase vigor of skin tissue, keep skin high resilience, shrink coarse pore, can make It is naturally honorable that dry cracked skin recovers it；Special treatment: new and old scar after improving and eliminating wound, as whelk, dark sore stay Concavo-convex hole, tan severely, scar that scar of burning, Post operation stay.Eliminate the blackout after changing skin and red and swollen phenomenon.Prevent and eliminate gestation Line；Preventing pigementation, Kohakuhi, the blackspot that disappears, freckle, age mark, chloasma, eye-care can eliminate livid ring around eye, eye Fat granule, granulation, flat wart.
1, combination medicament of the present invention " focus on entirety ", both can treat women alopecia areata, again can kidney tonifying, treat deficiency of qi and blood, Importantly being combined with Chinese medicine by plant, this is the big feature being different from drug therapy, and this combination medicament is complete It is prepared from according to traditional Chinese medicine principle, more safe and reliable, without any side effects, to matrix without any stimulation.
2, combination medicament of the present invention has effect of hair tonic, myogenic, can more fully treat women alopecia areata, general alopecia areata, The symptoms such as alopecia also prevent it from recurring.
3, medicinal material compatibility selected by combination medicament of the present invention is suitable, uses modern advanced pharmaceutical technology to make, evident in efficacy, Safe without toxic side effect, treats both principal and secondary aspect of disease, and should be widely promoted application.
Detailed description of the invention
Describe technical scheme in detail below in conjunction with embodiment and experimental example, but protection domain is not limited by this.
Embodiment 1 treats the combination medicament of women alopecia areata, takes off and states the primary raw material of weight proportion and be prepared from that (every part takes 10g): cutworm 5 parts, ginseng 4 parts, insect wax 10 parts, 10 parts of cultivated land, aloe 5 parts, ginger powder 7 parts, the seed of Chinese dodder 4 parts, 5 parts of rascal, The fruit of glossy privet 3 parts, 2 parts of rouge and powder, 5 parts of mulberry leaf, the fleece-flower root 3 parts, rose hip oil 5 parts.
The preparation method of combinations thereof medicament, step is as follows:
(1) aloe brush is cleaned down, remove thorn, then skin upper and lower for Chinese aloe leaf is also removed, rinse gel with water, will Gel is put in juice extractor squeezing 2 minutes, filters off residue, obtains asparagus juice stand-by；
(2) insect wax, ginger powder and rouge and powder are gone the removal of impurity, tight with fresh lotus leaf parcel, it is placed on steaming tray and steams 20 points Clock, taking-up is dried in the air cool, and step (1) gained asparagus juice is together mixed with the insect wax steamed, ginger powder and rouge and powder with rose hip oil Close, constantly stir with waddy, high-temperature sterilization 10 seconds, bottle medicine is smeared in external application；
(3) repeatedly stir-frying cutworm, cultivated land and the seed of Chinese dodder to crisp, grinding to form smalls, to cross 80 mesh sieves stand-by；
(4) ginseng, the fruit of glossy privet, mulberry leaf and the fleece-flower root are together placed in transparent container, add the warm water of 30 DEG C, clean dry Only, chopping, with yellow rice wine, the bulk drug of chopping to be mixed thoroughly, be placed in tinfoil, upper baking box is baked 3 minutes, takes out, dries in the air 10 minutes, lays On clean tile, little fire dries 3 minutes slowly, dries in the air to crisp, grinds to form smalls stand-by；
(5) being placed in marmite by rascal, add the clear water of rascal weight 4 times, big fire is boiled, and turns slow fire boiling 18 minutes, filters, Filtrate is stand-by；
(6) step (3) and (4) gained smalls are mixed, add in step (5) gained filtrate, be placed on electromagnetic oven heating While stirring, adding dextrin after mixing thoroughly completely, obtain mixed liquor and cross 180 mesh screen packs after dextrin melts completely, filtrate is Oral liquid medicine.
Embodiment 2 treats the combination medicament of women alopecia areata, takes off and states the primary raw material of weight proportion and be prepared from (every part Take 5g): cutworm 10 parts, ginseng 9 parts, insect wax 20 parts, 20 parts of cultivated land, aloe 15 parts, ginger powder 13 parts, the seed of Chinese dodder 10 parts, blue or green Skin 10 parts, the fruit of glossy privet 7 parts, 4 parts of rouge and powder, 10 parts of mulberry leaf, the fleece-flower root 8 parts, rose hip oil 15 parts.
The preparation method of combinations thereof medicament, step is as follows:
(1) aloe brush is cleaned down, remove thorn, then skin upper and lower for Chinese aloe leaf is also removed, rinse gel with water, will Gel is put in juice extractor squeezing 6 minutes, filters off residue, obtains asparagus juice stand-by；
(2) insect wax, ginger powder and rouge and powder are gone the removal of impurity, tight with fresh lotus leaf parcel, it is placed on steaming tray and steams 40 points Clock, taking-up is dried in the air cool, and step (1) gained asparagus juice is together mixed with the insect wax steamed, ginger powder and rouge and powder with rose hip oil Close, constantly stir with waddy, high-temperature sterilization 30 seconds, bottle medicine is smeared in external application；
(3) repeatedly stir-frying cutworm, cultivated land and the seed of Chinese dodder to crisp, grinding to form smalls, to cross 120 mesh sieves stand-by；
(4) ginseng, the fruit of glossy privet, mulberry leaf and the fleece-flower root are together placed in transparent container, add the warm water of 40 DEG C, clean dry Only, chopping, with yellow rice wine, the bulk drug of chopping to be mixed thoroughly, be placed in tinfoil, upper baking box is baked 7 minutes, takes out, dries in the air 30 minutes, lays On clean tile, little fire dries 8 minutes slowly, dries in the air to crisp, grinds to form smalls stand-by；
(5) being placed in marmite by rascal, add the clear water of rascal weight 10 times, big fire is boiled, and turns slow fire boiling 18 minutes, mistake Filter, filtrate is stand-by；
(6) step (3) and (4) gained smalls are mixed, add in step (5) gained filtrate, be placed on electromagnetic oven heating While stirring, adding dextrin after mixing thoroughly completely, obtain mixed liquor and cross 180 mesh screen packs after dextrin melts completely, filtrate is Oral liquid medicine.
Embodiment 3 treats the combination medicament of women alopecia areata, takes off and states the primary raw material of weight proportion and be prepared from (every part Take 15g): cutworm 6 parts, ginseng 5 parts, insect wax 13 parts, 13 parts of cultivated land, aloe 8 parts, ginger powder 9 parts, the seed of Chinese dodder 6 parts, rascal 6 Part, the fruit of glossy privet 4 parts, 2.5 parts of rouge and powder, 6 parts of mulberry leaf, the fleece-flower root 4 parts, rose hip oil 8 parts.
Stating the preparation method of combination medicament, step is as follows:
(1) aloe brush is cleaned down, remove thorn, then skin upper and lower for Chinese aloe leaf is also removed, rinse gel with water, will Gel is put in juice extractor squeezing 3 minutes, filters off residue, obtains asparagus juice stand-by；
(2) insect wax, ginger powder and rouge and powder are gone the removal of impurity, tight with fresh lotus leaf parcel, it is placed on steaming tray and steams 25 points Clock, taking-up is dried in the air cool, and step (1) gained asparagus juice is together mixed with the insect wax steamed, ginger powder and rouge and powder with rose hip oil Close, constantly stir with waddy, high-temperature sterilization 15 seconds, bottle medicine is smeared in external application；
(3) repeatedly stir-frying cutworm, cultivated land and the seed of Chinese dodder to crisp, grinding to form smalls, to cross 90 mesh sieves stand-by；
(4) ginseng, the fruit of glossy privet, mulberry leaf and the fleece-flower root are together placed in transparent container, add the warm water of 33 DEG C, clean dry Only, chopping, with yellow rice wine, the bulk drug of chopping to be mixed thoroughly, be placed in tinfoil, upper baking box is baked 4 minutes, takes out, dries in the air 15 minutes, lays On clean tile, little fire dries 4 minutes slowly, dries in the air to crisp, grinds to form smalls stand-by；
(5) being placed in marmite by rascal, add the clear water of rascal weight 6 times, big fire is boiled, and turns slow fire boiling 20 minutes, filters, Filtrate is stand-by；
(6) step (3) and (4) gained smalls are mixed, add in step (5) gained filtrate, be placed on electromagnetic oven heating While stirring, adding dextrin after mixing thoroughly completely, obtain mixed liquor and cross 190 mesh screen packs after dextrin melts completely, filtrate is Oral liquid medicine.
Embodiment 4 treats the combination medicament of women alopecia areata, takes off and states the primary raw material of weight proportion and be prepared from (every part Take 20g): cutworm 9 parts, ginseng 8 parts, insect wax 18 parts, 18 parts of cultivated land, aloe 13 parts, ginger powder 11 parts, the seed of Chinese dodder 8 parts, rascal 9 parts, the fruit of glossy privet 6 parts, 3.5 parts of rouge and powder, 9 parts of mulberry leaf, the fleece-flower root 7 parts, rose hip oil 13 parts.
The preparation method of combinations thereof medicament, step is as follows:
(1) aloe brush is cleaned down, remove thorn, then skin upper and lower for Chinese aloe leaf is also removed, rinse gel with water, will Gel is put in juice extractor squeezing 5 minutes, filters off residue, obtains asparagus juice stand-by；
(2) insect wax, ginger powder and rouge and powder are gone the removal of impurity, tight with fresh lotus leaf parcel, it is placed on steaming tray and steams 35 points Clock, taking-up is dried in the air cool, and step (1) gained asparagus juice is together mixed with the insect wax steamed, ginger powder and rouge and powder with rose hip oil Close, constantly stir with waddy, high-temperature sterilization 25 seconds, bottle medicine is smeared in external application；
(3) repeatedly stir-frying cutworm, cultivated land and the seed of Chinese dodder to crisp, grinding to form smalls, to cross 110 mesh sieves stand-by；
(4) ginseng, the fruit of glossy privet, mulberry leaf and the fleece-flower root are together placed in transparent container, add the warm water of 38 DEG C, clean dry Only, chopping, with yellow rice wine, the bulk drug of chopping to be mixed thoroughly, be placed in tinfoil, upper baking box is baked 6 minutes, takes out, dries in the air 10-30 minute, paving Being located on clean tile, little fire dries 8 minutes slowly, dries in the air to crisp, grinds to form smalls stand-by；
(5) being placed in marmite by rascal, add the clear water of rascal weight 8 times, big fire boils, and turns slow fire boiling 25 minutes (preferably Turn slow fire boiling 23 minutes), filter, filtrate is stand-by；
(6) step (3) and (4) gained smalls are mixed, add in step (5) gained filtrate, be placed on electromagnetic oven heating While stirring, adding dextrin after mixing thoroughly completely, obtain mixed liquor and cross 210 mesh screen packs after dextrin melts completely, filtrate is Oral liquid medicine.
Embodiment 5 treats the combination medicament of women alopecia areata, takes off and states the primary raw material of weight proportion and be prepared from (every part Take 30g): cutworm 7.5 parts, ginseng 6.5 parts, insect wax 15 parts, 15 parts of cultivated land, aloe 10 parts, ginger powder 10 parts, the seed of Chinese dodder 7 parts, 7.5 parts of rascal, the fruit of glossy privet 5 parts, 3 parts of rouge and powder, 8 parts of mulberry leaf, the fleece-flower root 5.5 parts, rose hip oil 10 parts.
The preparation method of combinations thereof medicament, step is as follows:
(1) aloe brush is cleaned down, remove thorn, then skin upper and lower for Chinese aloe leaf is also removed, rinse gel with water, will Gel is put in juice extractor squeezing 4 minutes, filters off residue, obtains asparagus juice stand-by；
(2) insect wax, ginger powder and rouge and powder are gone the removal of impurity, tight with fresh lotus leaf parcel, it is placed on steaming tray and steams 30 points Clock, taking-up is dried in the air cool, and step (1) gained asparagus juice is together mixed with the insect wax steamed, ginger powder and rouge and powder with rose hip oil Close, constantly stir with waddy, high-temperature sterilization 20 seconds, bottle medicine is smeared in external application；
(3) repeatedly stir-frying cutworm, cultivated land and the seed of Chinese dodder to crisp, grinding to form smalls, to cross 100 mesh sieves stand-by；
(4) ginseng, the fruit of glossy privet, mulberry leaf and the fleece-flower root are together placed in transparent container, add the warm water of 35 DEG C, clean dry Only, chopping, with yellow rice wine, the bulk drug of chopping to be mixed thoroughly, be placed in tinfoil, upper baking box is baked 5 minutes, takes out, dries in the air 20 minutes, lays On clean tile, little fire dries 6 minutes slowly, dries in the air to crisp, grinds to form smalls stand-by；
(5) being placed in marmite by rascal, add the clear water of rascal weight 7 times, big fire is boiled, and turns slow fire boiling 23 minutes, filters, Filtrate is stand-by；
(6) step (3) and (4) gained smalls are mixed, add in step (5) gained filtrate, be placed on electromagnetic oven heating While stirring, adding dextrin after mixing thoroughly completely, obtain mixed liquor and cross 200 mesh screen packs after dextrin melts completely, filtrate is Oral liquid medicine.
Test example 1: the clinical practice of the combination medicament of embodiment 5 gained treatment women alopecia areata: we have randomly drawed 400 Name patient tests (400 women patients with alopecia areatas), is divided into experimental group and control group, before test 1 week, enters this crowd Row Continuous Observation, record symptom and change, it is randomly divided into two groups, experimental group and control group, experimental group uses embodiment 5 gained to produce Product, control group takes the medicine of other treatment women alopecia areata.
Optimal using method: for making the present invention reach optimal result for the treatment of, the external application made is smeared medicine and smeared number every day Secondary, directly it is put on affected part, oral liquid medicine, takes effect more preferably with 3 of afternoon, within 5 days, be one for 10 of every morning The course for the treatment of.
Efficacy evaluation: cure: malaise symptoms all disappears, hair is slowly longer；Effective: clinical symptom relief；Nothing Effect: clinical symptoms are without significant change.
Specific experiment result such as following table:
Table 1:
Result for the treatment of: combination medicament result for the treatment of of the present invention is substantially better than control group, and during use, malaise symptoms occurs in no one Or side effect.

Claims (10)

1. treat the combination medicament of women alopecia areata, it is characterised in that: take off and state the primary raw material of weight proportion and be prepared from: cutworm 5-10 part, ginseng 4-9 part, insect wax 10-20 part, cultivated land 10-20 part, aloe 5-15 part, ginger powder 7-13 part, seed of Chinese dodder 4-10 Part, rascal 5-10 part, fruit of glossy privet 3-7 part, rouge and powder 2-4 part, mulberry leaf 5-10 part, fleece-flower root 3-8 part, rose hip oil 5-15 part.
The combination medicament for the treatment of women alopecia areata the most according to claim 1, it is characterised in that: take off the master stating weight proportion Raw material is wanted to be prepared from: cutworm 6-9 part, ginseng 5-8 part, insect wax 13-18 part, cultivated land 13-18 part, aloe 8-13 part, ginger Powder 9-11 part, seed of Chinese dodder 6-8 part, rascal 6-9 part, fruit of glossy privet 4-6 part, rouge and powder 2.5-3.5 part, mulberry leaf 6-9 part, fleece-flower root 4-7 Part, rose hip oil 8-13 part.
The combination medicament for the treatment of women alopecia areata the most according to claim 1, it is characterised in that: take off and state weight proportion Primary raw material is prepared from: cutworm 7.5 parts, ginseng 6.5 parts, insect wax 15 parts, 15 parts of cultivated land, aloe 10 parts, ginger powder 10 parts, The seed of Chinese dodder 7 parts, 7.5 parts of rascal, the fruit of glossy privet 5 parts, 3 parts of rouge and powder, 8 parts of mulberry leaf, the fleece-flower root 5.5 parts, rose hip oil 10 parts.
4. according to the preparation method of the combination medicament of the treatment women alopecia areata described in any one of claim 1-3, it is characterised in that: Step is as follows:
(1) aloe brush is cleaned down, remove thorn, then skin upper and lower for Chinese aloe leaf is also removed, rinse gel with water, will Gel is put in juice extractor 2-6 minute (preferably 4 minutes) of squeezing, filters off residue, obtains asparagus juice stand-by；
(2) insect wax, ginger powder and rouge and powder are gone the removal of impurity, tight with fresh lotus leaf parcel, it is placed on steaming tray and steams 20-40 Minute, take out dry in the air cool, by step (1) gained asparagus juice and rose hip oil together with the insect wax steamed, ginger powder and rouge and powder Mixing, constantly stir with waddy, the high-temperature sterilization 10-30 second, bottle medicine is smeared in external application；
(3) repeatedly stir-frying cutworm, cultivated land and the seed of Chinese dodder to crisp, grinding to form smalls, to cross 80-120 mesh sieve stand-by；
(4) ginseng, the fruit of glossy privet, mulberry leaf and the fleece-flower root are together placed in transparent container, add the warm water of 30-40 DEG C, clean Totally, chopping, with yellow rice wine, the bulk drug of chopping to be mixed thoroughly, be placed in tinfoil, upper baking box is baked 3-7 minute, takes out, and the 10-30 that dries in the air divides Clock, is laid on clean tile, and little fire dries 3-8 minute slowly, dries in the air to crisp, grinds to form smalls stand-by；
(5) being placed in marmite by rascal, add the clear water of rascal weight 4-10 times, big fire is boiled, and turns slow fire boiling 18-28 minute (preferably turning slow fire boiling 23 minutes), filters, and filtrate is stand-by；
(6) step (3) and (4) gained smalls are mixed, add in step (5) gained filtrate, be placed on electromagnetic oven heating While stirring, after mixing thoroughly completely, add dextrin, after dextrin melts completely, obtain mixed liquor cross 180-220 mesh screen pack, filtrate It it is oral liquid medicine.
The preparation method of combination medicament the most according to claim 4, it is characterised in that: step (2) is with fresh lotus leaf bag Wrap up in tight, be placed on steaming tray to steam 25-35 minute and (preferably, wrap up tight with fresh lotus leaf, be placed on steaming tray and steam 30 points Clock).
The preparation method of combination medicament the most according to claim 4, it is characterised in that: step (3) grinds to form smalls and crosses 90- 110 mesh sieves stand-by (preferably, grind to form smalls cross 100 mesh sieves stand-by).
The preparation method of combination medicament the most according to claim 4, it is characterised in that: the consumption of step (4) yellow rice wine is mixed (preferably, the consumption of yellow rice wine is 0.4-0.6 times of mixing bulk drug, more preferably, yellow rice wine to 0.3-0.7 times of conjunction bulk drug Consumption be mixing 0.5 times of bulk drug).
The preparation method of combination medicament the most according to claim 4, it is characterised in that: step (4) is dried in the air 15-25 minute, paving Being located on clean tile, little fire dries 4-7 minute slowly, and (preferably, drying in the air 20 minutes, be laid on clean tile, little fire dries 5 slowly Minute).
The preparation method of combination medicament the most according to claim 4, it is characterised in that: step (5) adds rascal weight 6-8 Clear water again (preferably, adds the clear water of rascal weight 7 times).
The preparation method of combination medicament the most according to claim 4, it is characterised in that: step (6) treats that dextrin melts completely After 190-210 mesh screen pack (preferably after dextrin melts completely mixed liquor cross 200 mesh screen packs) crossed by mixed liquor.
CN201610491981.3A 2016-06-29 2016-06-29 Combined medicament for treating female alopecia areata and preparation method thereof Pending CN105902993A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610491981.3A CN105902993A (en) 2016-06-29 2016-06-29 Combined medicament for treating female alopecia areata and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610491981.3A CN105902993A (en) 2016-06-29 2016-06-29 Combined medicament for treating female alopecia areata and preparation method thereof

Publications (1)

Publication Number Publication Date
CN105902993A true CN105902993A (en) 2016-08-31

Family

ID=56759933

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610491981.3A Pending CN105902993A (en) 2016-06-29 2016-06-29 Combined medicament for treating female alopecia areata and preparation method thereof

Country Status (1)

Country Link
CN (1) CN105902993A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109793918A (en) * 2018-12-29 2019-05-24 中国人民解放军总医院 It can promote the plant society dressing of extensive wound hair follicle regeneration

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101371904A (en) * 2007-08-20 2009-02-25 石家庄市神露保健品有限公司 Chinese herbal medicine for treating alopecia and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101371904A (en) * 2007-08-20 2009-02-25 石家庄市神露保健品有限公司 Chinese herbal medicine for treating alopecia and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
国家药典委员会: "《中华人民共和国药典 2015年版 一部》", 30 June 2015, 中国医药科技出版社 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109793918A (en) * 2018-12-29 2019-05-24 中国人民解放军总医院 It can promote the plant society dressing of extensive wound hair follicle regeneration
CN109793918B (en) * 2018-12-29 2021-02-12 中国人民解放军总医院 Plant composite dressing capable of promoting large-area wound hair follicle regeneration

Similar Documents

Publication Publication Date Title
JP5646117B2 (en) Hair growth promoter and production method
CN103735835B (en) A kind of Chinese medicine preparation for the treatment of young person with greying hair and preparation method thereof
CN103931957B (en) Chicken feed and traditional Chinese medicine composition for preventing and treating chicken infectious anemia
CN104547584A (en) Traditional Chinese medicine spray capable of promoting healing of incision after cesarean section surgery and preparation method of traditional Chinese medicine spray
CN102526694B (en) Lotion beneficial to health of anus and preparation method thereof
CN107661270A (en) A kind of shampoo for promoting dark hair to grow and its preparation and application
CN105902993A (en) Combined medicament for treating female alopecia areata and preparation method thereof
CN105943799A (en) Compound preparation for treating contact dermatitis and preparation method thereof
CN105362663A (en) Traditional Chinese medicine preparation for treating juvenile poliosis
CN105343502A (en) Health-care oral liquid capable of improving immunity
CN105055931A (en) Traditional Chinese medicine preparation for treating chronic obstructive pulmonary disease
CN104689283A (en) Medicine for treatment of spleen insufficiency damp-aggregating type chloasma and preparation method thereof
CN104645063A (en) Pills for treating hyperplasia of mammary glands and preparation method thereof
CN104498298B (en) A kind of jowar wine and preparation method thereof
CN103845678A (en) Pharmaceutical composition for treating infantile dermatitis
CN105343525A (en) Traditional Chinese medicine preparation capable of promoting hair regeneration and blacking and brightening hairs
CN105942397A (en) Broth for treating insomnia and dysphoria and preparation method thereof
CN106689490A (en) Crneate Lespedeza tea capable of tonifying kidney and arresting seminal emission, and preparation method thereof
CN105194518A (en) Traditional Chinese medicine for treating neurogenic endocrine dysfunction
CN105106799A (en) Prescription for treating ovarian cancer and preparation method
CN104800687A (en) Traditional Chinese medicine preparation for treating infantile malnutrition and preparation method thereof
CN104491403A (en) Medicine for treating central retinochoroiditis and preparation method
CN104524035A (en) Traditional Chinese medicine for treating prosopospasm and preparation method thereof
CN105106670A (en) Composition for relieving hand and foot numbness caused by cerebral hemorrhage and preparing method thereof
CN104147433A (en) Traditional Chinese medicine used for treating hyperthyroidism

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20160831

RJ01 Rejection of invention patent application after publication