CN105902760A - Traditional Chinese medicine for treating rabbit gastroenteritis - Google Patents

Traditional Chinese medicine for treating rabbit gastroenteritis Download PDF

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Publication number
CN105902760A
CN105902760A CN201610412587.6A CN201610412587A CN105902760A CN 105902760 A CN105902760 A CN 105902760A CN 201610412587 A CN201610412587 A CN 201610412587A CN 105902760 A CN105902760 A CN 105902760A
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parts
rabbit
chinese medicine
gastroenteritis
traditional chinese
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CN201610412587.6A
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CN105902760B (en
Inventor
邓凯伟
张丁华
王艳丰
尚马飞
酒雅丽
曹智高
陈海燕
刘守铉
庞歌
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Xinyang Agriculture and Forestry University
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Xinyang Agriculture and Forestry University
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Priority to CN201610412587.6A priority Critical patent/CN105902760B/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/15Pinaceae (Pine family), e.g. pine or cedar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/739Sanguisorba (burnet)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

Abstract

The invention discloses a traditional Chinese medicine for treating rabbit gastroenteritis, and belongs to the field of traditional Chinese medicines for animals. The traditional Chinese medicine is mainly prepared from, by weight, 30-40 parts of common andrographis herb, 50-70 parts of cortex fraxini, 35-50 parts of honeysuckle flowers, 30-50 parts of charred radix sanguisorbae, 50-70 parts of Chinese yam rhizomes and 30-50 parts of stir-fried hawthorn fruit. The traditional Chinese medicine is low in cost and high in cure rate when the traditional Chinese medicine is used for treating the rabbit gastroenteritis, and due to the fact that pure traditional Chinese medicine raw materials are adopted, medicine resistance of rabbits can not occur.

Description

A kind of Chinese medicine treating rabbit gastroenteritis
Technical field
The invention belongs to Animal Medicine field, be specifically related to a kind of Chinese medicine treating rabbit gastroenteritis.
Background technology
The inflammation that rabbit gastroenteritis is caused by long-term abnormal stimulation mainly due to gastrointestinal mucosa, feed collocation is uncomfortable The reasons such as preferably, feeding quality is the best, freshness is bad, daily ration ratio is improper, modulator approach is unreasonable, sanitary condition is poor all can be drawn Play gastroenteritis.The change of food during weather reason can aggravate rabbit gastrointestinal in addition harmful microorganism the destruction of rabbit gastrointestinal is made With, and the mild diarrhea of long period can be caused, thus cause, inflammation disease as principal character abnormal with gastrointestinal mucosa layer. Rabbit gastroenteritis is a kind of commonly encountered diseases of rabbit, frequently-occurring disease, the biggest to rabbit harm.The particularly young rabbit after wean, rabbit gastroenteritis Fatality rate be up to more than 70%.Antibiotic and chemicals is generally used to treat at present in the treatment of rabbit gastroenteritis, but Being to damage the beneficial microbe colony in rabbit gastrointestinal, the Drug resistance of antibiotic also can be strengthened by rabbit simultaneously, improves Treatment difficulty, adds production cost.
Summary of the invention
It is an object of the invention to provide the Chinese medicine of the high treatment rabbit gastroenteritis of a kind of cure rate.
Based on above-mentioned purpose, the present invention by the following technical solutions: a kind of Chinese medicine treating rabbit gastroenteritis, mainly by following The crude drug of weight portion is prepared from: Herba Andrographis 30 ~ 40 parts, Cortex Fraxini 50 ~ 70 parts, Flos Lonicerae 35 ~ 50 parts, charred Radix Sanguisorbae 30 ~ 50 Part, Rhizoma Dioscoreae 50 ~ 70 parts, Fructus Crataegi (parched) 30 ~ 50 parts.
Preferably, Herba Andrographis 30 parts, Cortex Fraxini 60 parts, Flos Lonicerae 45 parts, charred Radix Sanguisorbae 30 parts, Rhizoma Dioscoreae 60 parts, Fructus Crataegi (parched) 30 parts.
Preferably, described crude drug also includes pine needle powder 70 ~ 80 parts, carrot tops 100 ~ 120 parts.
Preferably, described Chinese medicine is the decocting liquid of each crude drug.
The Chinese medicine of above-mentioned treatment rabbit gastroenteritis uses following methods to prepare: by Herba Andrographis, Cortex Fraxini, Flos Lonicerae, charred Radix Sanguisorbae, mountain Medicine, Fructus Crataegi (parched), pine needle powder, carrot tops are mixed in proportion, pulverize, and add 3 ~ 4 times of water, fried 60 ~ 80 minutes;Leaching is crossed after fried Decocting liquid;Residual drug add water repeat fried, filter twice;Use after three decocting liquid mixing.
Consumption: once, depending on the body weight of how many foundation rabbits of each dosage, body weight is more than 4 kilograms in medication every day Rabbit take decocting liquid 15ml;The rabbit that body weight is 2 kilograms ~ 4 kilograms takes decocting liquid 12ml;The rabbit that body weight is 1 kilogram ~ 2 kilograms takes Decocting liquid 8ml;1 kilogram of rabbit once of body weight takes decocting liquid 5ml.
Wherein, Herba Andrographis: bitter in the mouth, cold in nature, GUIXIN, lung, large intestine, bladder warp;Having heat-clearing and toxic substances removing, removing heat from blood is subsided a swelling, antibacterial Antiinflammatory, antiviral, anti-liver injury, strengthen effect of immunity;Cure mainly acute bacillary dysentery, gastroenteritis, flu, epidemic encephalitis, tracheitis, lung Inflammation, pertussis, pulmonary tuberculosis, lung abscess, cholecystitis, hypertension, oropharynx swell and ache, furuncle carbuncle, burn due to hot liquid or fire.Medical science is thought now The andrographolide contained in Herba Andrographis has good curative effect to bacillary dysentery and enteritis.
Cortex Fraxini: bitter in the mouth, cold in nature, enter Liver Channel, gallbladder meridian, large intestine channel;There is heat clearing and damp drying, liver heat removing and eyesight improving, the merit of astringent therapy dysentery relieving Effect;There is resisting pathogenic microbes effect, to staphylococcus aureus, escherichia coli, shigella flexneri, bacterium sonnei, Micrococcus catarrhalis, streptococcus, neisser's diplococcus all have inhibitory action.It is used for damp-heat dysentery, tenesmus, bacillary dysentery clinically The treatment of disease.
Flos Lonicerae: sweet in the mouth, cold in nature, enter lung, the heart, stomach warp;There is heat-clearing and toxic substances removing, antiinflammatory, effect of qi-restoratives treatment wind, cure mainly swollen Disease, epidemic febrile disease is completely descended to generate heat, the disease such as pyretic toxicity carbuncle and ulcer and tumor.Modern study proves, Flos Lonicerae contains chlorogenic acid, luteolin glycosides etc. Pharmacological component, to the various pathogens such as Hemolytic streptococcus, staphylococcus aureus and upper respiratory tract infection Causative virus etc. There is stronger restraint.Be used for clinically, enteritis, bacillary dysentery, measles, pneumonia, encephalitis b, epidemic encephalitis, acute mastitis, septicemia, door screen Tail inflammation, skin infection, carbuncle furuncle, erysipelas, parotitis, the treatment of suppurative tonsillitis.
Charred Radix Sanguisorbae: property is bitter, sour in the mouth is cool, enters liver, stomach, large intestine channel;Charred Radix Sanguisorbae belongs to hemorrhage, has cooling blood for hemostasis, removing toxic substances Sore effect, is the treatment various hemorrhage common drug of heat in blood.
Fructus Crataegi (parched): sour in the mouth is sweet, enters spleen, stomach, Liver Channel;There are promoting digestion and invigorating the stomach, activating blood circulation to dissipate blood stasis, the function of convergence dysentery relieving;Meat is amassed Phlegm retention, feeling of fullness acid regurgitation, dysentery hemorrhoidal hamorrhage, lumbago hernia, the most effective in cure.
Contained by Rhizoma Dioscoreae can diastatic diastase, be 3 times of content in Radix Raphani, edible during flatulence, have promotion The effect of digestion, can remove malaise symptoms, be conducive to improving taste and digest and assimilate merit.
Pine needle powder: bitter in the mouth, puckery, warm in nature;There is expelling wind and activating blood circulation, improving eyesight, calm the nerves, removing toxic substances, antipruritic, antihalitosis, removes xerostomia tongue Effect that is dry, that treat constipation.For influenza, rheumatic arthritis, treating swelling and pain by traumatic injury, nyctalopia, hypertension, neurasthenia; External treating chilblain;Rich in aminoacid, vitamin and various trace elements necessary to animal growth, to promoting growth of animals or poultry Growth, enhancing premunition and raising reproductive function etc. have obvious facilitation.
Carrot tops: sweet in the mouth, property is put down;There is spleen invigorating and support spleen, nourishing the stomach stomach invigorating, blood-supplementing blood-nourishing, invigorating vital QI, raising immunity Effect;It is applicable to the disease such as hypertension and dyspepsia, chronic dysentery, nyctalopia, malnutrition.
The Chinese medicine low cost that the present invention provides, has anti-inflammation, antidiarrheal, nourishing the stomach stomach invigorating, enhancing body resistivity Effect, it is possible to the disease for the treatment of rabbit gastroenteritis, the generation of prevention rabbit gastroenteritis, cure rate is high, and owing to using pure raw material of Chinese medicine, Rabbit will not produce drug resistance.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in detail.
Embodiment 1
A kind of Chinese medicine treating rabbit gastroenteritis, is prepared from by the crude drug of following weight parts: Herba Andrographis 30g, Cortex Fraxini 60g, gold Flos Lonicerae 45g, charred Radix Sanguisorbae 30g, Rhizoma Dioscoreae 60 g, Fructus Crataegi (parched) 30g, pine needle powder 70g, carrot tops 100g.
The Chinese medicine of above-mentioned treatment rabbit gastroenteritis uses following methods to prepare: by Herba Andrographis, Cortex Fraxini, Flos Lonicerae, charred Radix Sanguisorbae, mountain Medicine, Fructus Crataegi (parched), pine needle powder, carrot tops are mixed in proportion, pulverize, and add 1000ml water, fried 60 ~ 80 minutes;Leaching is crossed after fried Decocting liquid;Residue medicinal residues add water and repeat fried, filter process twice;Use after three decocting liquid mixing.
Embodiment 2
A kind of Chinese medicine treating rabbit gastroenteritis, is prepared from by the crude drug of following weight parts: Herba Andrographis 35g, Cortex Fraxini 60g, gold Flos Lonicerae 40g, charred Radix Sanguisorbae 40g, Rhizoma Dioscoreae 60g, Fructus Crataegi (parched) 40g, pine needle powder 75g, carrot tops 110g.
Its preparation method is same as in Example 1.
Embodiment 3
A kind of Chinese medicine treating rabbit gastroenteritis, is prepared from by the crude drug of following weight parts: Herba Andrographis 40g, Cortex Fraxini 50g, Flos Lonicerae 35g, charred Radix Sanguisorbae 50g, Rhizoma Dioscoreae 70g, Fructus Crataegi (parched) 50g, pine needle powder 70g, carrot tops 120g.
Its preparation method is same as in Example 1.
Embodiment 4
A kind of Chinese medicine treating rabbit gastroenteritis, is prepared from by the crude drug of following weight parts: Herba Andrographis 30 g, Cortex Fraxini 70 g, Flos Lonicerae 50 g, charred Radix Sanguisorbae 30g, Rhizoma Dioscoreae 50g, Fructus Crataegi (parched) 30g, pine needle powder 80g, carrot tops 100g.
Its preparation method is same as in Example 1.
Effect experimental
Test 1
Subjects: certain rabbit warren is grown up rex rabbit 200.
Symptom and analysis: find loss of appetite, dyspepsia and mucus in stool.Then occur having loose bowels, arrange scattered paste shape Or water sample excrement, feces distributes stench, and be mixed with mucus, the mucosa that comes off and do not digest forage completely.Find after dissecting, intestinal Edema under mucosa, hemorrhage or downright bad, after peeling off slough, it is seen that the speck left over or ulcer.According to field investigation, the cause of disease Analysis, cardinal symptom and pathological change, it is judged that be owing to feeding the rabbit gastroenteritis that the rabbit grain gone mouldy occurs.
Process of the test: 200 rex rabbit stochastic averagina are divided into 2 groups, often group 100, be designated as testing 1 group and test 2 respectively Group, tests 1 group of traditional Chinese medicine decoction taking embodiment 1 preparation, tests 2 groups of traditional Chinese medicine decoctions taking embodiment 2 preparation.Medication every day Once, each consumption is: body weight rabbit more than 4 kilograms takes decocting liquid 15ml;The rabbit that body weight is 2 kilograms ~ 4 kilograms takes pan-fried Liquid 12ml;The rabbit that body weight is 1 kilogram ~ 2 kilograms takes decocting liquid 8ml;1 kilogram of rabbit once of body weight takes decocting liquid 5ml.Record is controlled respectively Treating the healing number of lazy rabbit after 3d, 5d and final death toll, concrete outcome is shown in Table 1.
From the data of table 1, the Chinese medicine that the present invention provides has obvious curative effect, and embodiment to treatment rabbit gastroenteritis The curative effect of the Chinese medicine that the curative effect of 1 is prepared apparently higher than embodiment 2.
Test 2
Subjects: 120 Pili in Fetus of Haired Rabbits that certain raiser raises.
Symptom and analysis: feces, with bubble, is mingled with the mucus of red white nasal mucus sample.Sick rabbit often with formula bowel movement of squatting, and Times of defecation is many and Fecal wastes is few.Edema under intestinal mucosa, hemorrhage.According to cardinal symptom and pathological change and test in laboratory, Make a definite diagnosis is owing to feeding the rabbit gastroenteritis that the rabbit grain of e. coli contamination occurs.
Process of the test: 120 Pili in Fetus of Haired Rabbit stochastic averagina are divided into 2 groups, often group 60, be designated as testing A group and test B group, Test A group takes the traditional Chinese medicine decoction of embodiment 1 preparation, and test B group takes the traditional Chinese medicine decoction of embodiment 2 preparation..Medication one every day Secondary, each consumption is: body weight rabbit more than 4 kilograms takes decocting liquid 15ml;The rabbit that body weight is 2 kilograms ~ 4 kilograms takes decocting liquid 12ml;The rabbit that body weight is 1 kilogram ~ 2 kilograms takes decocting liquid 8ml;1 kilogram of rabbit once of body weight takes decocting liquid 5ml.Record treatment respectively The healing number of Pili in Fetus of Haired Rabbit rabbit and final death toll after 3d, 5d, concrete outcome is shown in Table 2.
From the data of table 1, the Chinese medicine that the present invention provides has obvious curative effect, and embodiment to treatment rabbit gastroenteritis The curative effect of the Chinese medicine that the curative effect of 1 is prepared apparently higher than embodiment 2.
Test 3
Subjects: certain foster rex rabbit field rabbit 100, uses rabbit grain to feed after wean.
Symptom and analysis: due to the transition period not having rabbit grain to feed, cause rabbit and get rid of wet rotten feces and have evil Stink, belly tympanites.But children rabbit still has appetite, is due to dyspeptic rabbit stomach according to etiological analysis, cardinal symptom and judgement Enteritis.
Process of the test: every young rabbit takes the decocting liquid 5ml of embodiment 1 every day.The healing of children rabbit after record treatment 3d, 5d Number and final death toll, concrete outcome is shown in Table 3.

Claims (4)

1. the Chinese medicine treating rabbit gastroenteritis, it is characterised in that be mainly prepared from by the crude drug of following weight parts: punching 30 ~ 40 parts of lotus, Cortex Fraxini 50 ~ 70 parts, Flos Lonicerae 35 ~ 50 parts, charred Radix Sanguisorbae 30 ~ 50 parts, Rhizoma Dioscoreae 50 ~ 70 parts, Fructus Crataegi (parched) 30 ~ 50 parts.
The Chinese medicine for the treatment of rabbit gastroenteritis the most according to claim 1, it is characterised in that Herba Andrographis 30 parts, Cortex Fraxini 60 parts, gold Flos Lonicerae 45 parts, charred Radix Sanguisorbae 30 parts, Rhizoma Dioscoreae 60 parts, Fructus Crataegi (parched) 30 parts.
The Chinese medicine for the treatment of rabbit gastroenteritis the most according to claim 1 and 2, it is characterised in that described crude drug also includes pine 70 ~ 80 parts of pin powder, carrot tops 100 ~ 120 parts.
The Chinese medicine for the treatment of rabbit gastroenteritis the most according to claim 3, it is characterised in that described Chinese medicine is decocting of each crude drug Liquid.
CN201610412587.6A 2016-06-14 2016-06-14 A kind of Chinese medicine for treating rabbit stomach enteritis Expired - Fee Related CN105902760B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106177380A (en) * 2016-08-31 2016-12-07 梁小荣 The Chinese medicine preparation of preventing and treating Holland dwarf's rabbit gastroenteritis disease and preparation method

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104147097A (en) * 2014-09-02 2014-11-19 扬中牧乐药业有限公司 Traditional Chinese medicinal granule for treating gastroenteritis of rex rabbit
CN105250825A (en) * 2015-11-09 2016-01-20 陈鹏举 Traditional Chinese medicine composition for treating and preventing livestock, poultry and fur-bearing animal gastroenteritis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104147097A (en) * 2014-09-02 2014-11-19 扬中牧乐药业有限公司 Traditional Chinese medicinal granule for treating gastroenteritis of rex rabbit
CN105250825A (en) * 2015-11-09 2016-01-20 陈鹏举 Traditional Chinese medicine composition for treating and preventing livestock, poultry and fur-bearing animal gastroenteritis

Non-Patent Citations (1)

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傅春贵: "治兔胃肠炎八验方", 《河北畜牧兽医》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106177380A (en) * 2016-08-31 2016-12-07 梁小荣 The Chinese medicine preparation of preventing and treating Holland dwarf's rabbit gastroenteritis disease and preparation method

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