CN105901723A - 一种降血糖南极磷虾油保健胶囊 - Google Patents
一种降血糖南极磷虾油保健胶囊 Download PDFInfo
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Abstract
本发明公开了一种降血糖南极磷虾油保健胶囊，是由南极磷虾油和中草药原料科学配伍，优选得南极磷虾油30～40份、海藻15～20份、枸杞15～18份、葛根10～14份、桑椹8～10份、甘草8～10份、生地6～10份、白术4～8份、丹参5～8份、当归4～6份、知母4～6份、玉米须4～6份、赤芍3～5份、天冬2～3份配方，然后按调配、混合、灭菌、灌装胶囊工艺制备。该产品优势在于通过南极磷虾油和中草药之间的协同作用具有显著的降血糖、补气补益、扶正固本，抗疲劳、延年益寿等功效，安全无副作用，食用方便，具有较好的市场应用前景。
Description
技术领域
本发明涉及一种降血糖南极磷虾油保健胶囊，特别是一种以南极磷虾油和植物中草药为原料制成的保健胶囊，属保健食品领域。
背景技术
南极洲是地球上唯一没有受到污染的大陆，曾被誉为“洁白无瑕”的世界，是地球上的最后一块“净土”。南极大陆周围的海洋被称为富饶、洁净的“海上牧场”，海洋里充满了生机，那里有海藻、珊瑚、海星和海绵，大海里还有许许多多叫做磷虾的微小生物，它是南极洲众多的鱼类、海鸟、海豹、企鹅以及鲸类赖以生存的食物，它在南大洋食物链中起着十分重要的作用。南极磷虾是继粮食、石油、煤炭之后的地区第四大资源。南极磷虾的蕴藏量十分惊人， 而且营养价值极高。它是人们今天已经发现的含蛋白质最高的生物，蛋白质含量达百分之五十以上，而且还含有极为丰富的人体组织所必需的氨基酸和维生素A。南极磷虾油取自纯正野生南极磷虾，利用专利超低温萃取的方式提取，是大自然馈赠给人类的天然健康食品，含有其他食品不能替代的功效。美国临床证实，磷虾油具有超强的降血脂，降血糖，降血压，穿越血脑屏障营养及活化脑部细胞和神经，起到预防和治疗脑血管疾病；同时，预防和治疗冠状动脉粥样硬化，冠心病，预防发生心梗、支架、搭桥及二次复发等心血管疾病；此外，南极磷虾油还可以起到抗菌消炎，预防癌症的发生发展，延缓疲劳，调节内分泌等多重功效。
糖尿病（diadetes mellitus）是一组以长期高血糖为主要特征的代谢综合征,它是由于胰岛素缺乏和、或胰岛素生物作用障碍导致糖代谢紊乱，同时伴随脂肪、蛋白质、水和电解质代谢障碍，可并发眼、肾、神经、心血管等多器官的慢性损伤。其患病率正随着人民生活水平的提高，人口老化，生活方式的改变而迅速增加，已成为继心血管病和肿瘤之后的第三大非传染性疾病，对社会和经济带来沉重的负担。由于对糖尿病的病因和发病机制尚未充分明了，目前还没有一种药物能治愈糖尿病，患者需终身服药维持血糖平衡。近二十年来，保健食品发展非常迅猛，逐渐被人们所重视。具有辅助降血糖功能的保健食品对糖尿病患者生活质量的改善十分有益，受到越来越多患者的青睐。
中草药资源是我国传统文化的瑰宝，因其功效显著、绿色、安全、无副作用，在保健食品领域中的应用愈加广泛。研究结果表明，利用中草药研制的保健品含有丰富的营养成分，不但保留了中草药中原有的多糖、黄酮、氨基酸、钾钙等微量元素、维生素等活性营养成分，而且在生产过程中产生了大量的糖、蛋白质、人体必需氨基酸等营养成分，长期合理食用能够调节人体机能，增强免疫力、滋补强身、延年益寿等功效。近年来中草药被越来越多的用于预防和治疗糖尿病，但其应用效果亟需进一步提升。
目前，中草药在保健食品领域中的应用还存在较多的弊端，难以真正发挥中草药的保健功效。本发明针对上述问题，开发一种利用南极磷虾油和复合中草药的具有降血糖功效的保健胶囊，满足市场对南极磷虾油和中草药保健食品的需求。
发明内容
为克服现有技术的不足，本发明的目的在于提供一种降血糖南极磷虾油保健胶囊，该保健胶囊具有降血糖、补气补益、扶正固本，抗疲劳、延年益寿等功效，满足日益增多的糖尿病患者对高效、安全、无害降血糖保健品的需求。
本发明上述目的是通过以下技术方案予以实现的：
本发明提供一种降血糖南极磷虾油保健胶囊，其特征在于保健胶囊原料组成及质量配比为：南极磷虾油30～40份、海藻15～20份、枸杞15～18份、葛根10～14份、桑椹8～10份、甘草8～10份、生地6～10份、白术4～8份、丹参5～8份、当归4～6份、知母4～6份、玉米须4～6份、赤芍3～5份、天冬2～3份。
本发明的优选技术方案是：一种降血糖南极磷虾油保健胶囊，其特征在于：其特征在于保健胶囊原料组成及质量配比为：南极磷虾油35份、海藻18份、枸杞16份、葛根12份、桑椹9份、甘草9份、生地8份、白术6份、丹参6份、当归5份、知母5份、玉米须5份、赤芍4份、天冬2.5份。
本发明提供一种降血糖南极磷虾油保健胶囊，其特征在于通过以下步骤制备：
（1）原料预处理：将所用中草药分拣，去除杂质、霉变和有病虫害的原料等；
（2）干燥：将原料分别在微波真空干燥机中干燥至恒重；
（3）粉碎：分别将南极磷虾油和中草药原料用超微型粉碎机粉碎，过2000目筛；
（4）称量调配：将粉碎后的原料按照上述比例调配；
（5）混合：将调配好的原料用高速混合搅拌机充分混合均匀；
（6）灭菌：用钴-60灭菌；
（7）灌装胶囊：在洁净室内用0号胶囊灌装；
（8）成型产品：将灌装后的胶囊装瓶，贴标，喷码即得具有降血糖功效的南极磷虾油保健胶囊。
本发明提供一种降血糖南极磷虾油保健胶囊，通过动物试验进行保健胶囊的毒理学试验及安全性评价。小鼠急性经口毒性试验结果表明，本保健胶囊对小鼠急性经口最大耐受剂量大于高剂量组75mg/kg·bw； 遗传毒性试验小鼠骨髓细胞微核试验和小鼠精子畸形试验两项试验结果均为阴性，表明该保健胶囊无致突变作用；由大鼠30d喂养试验可知，大鼠体征行为正常、体态健康、血液及血液生化指标也无异常变化，因此75mg/kg·bw的剂量（人体推荐量的150倍）属于安全剂量；遗传毒性试验和大鼠30d喂养试验结果均为阴性，因此确定本保健胶囊属无毒类食品，人可以安全放心食用。
本发明提供一种降血糖南极磷虾油保健胶囊，其优势在于科学配伍南极磷虾油和多种中草药，通过南极磷虾油和中草药之间的协同作用能有效降血糖、补气补益、扶正固本，抗疲劳、延年益寿等功效，安全无副作用，食用方便。不同的中草药性味各异，功效存在着巨大的差异，不同的中草药组合后存在复杂的相互作用关系，且中草药之间的配比比较密切，不同配比也将使君臣佐使关系发生实质性的变化，从而使复合中草药的关系发生实质性改变。本申请通过南极磷虾油与海藻、枸杞、葛根、桑椹、甘草、生地、白术、丹参、当归、知母、玉米须、赤芍、天冬等中草药彼此间存在复杂的相互作用关系，合理配比，取得了预料不到的技术效果，使保健胶囊的关系发生实质性改变，饲喂本胶囊三周后的造模试验组与对照组相比血糖含量下降43.52%，说明产品具有较好的降血糖活性；且试验结果表明改变保健胶囊原料组成或配比会降低保健胶囊的降血糖能力（P<0.01），说明南极磷虾油和中草药之间的协同作用起到了显著提升保健胶囊功能活性的作用。
具体实施方式
下面结合实施例对本发明做进一步说明。
实施例
1
：
一种降血糖南极磷虾油保健胶囊，通过以下步骤制备：
（1）原料预处理：将所用中草药分拣，去除杂质、霉变和有病虫害的原料等；
（2）干燥：将原料分别在微波真空干燥机中干燥至恒重；
（3）粉碎：分别将南极磷虾油和中草药原料用超微型粉碎机粉碎，过2000目筛；
（4）称量调配：将粉碎后的原料按照南极磷虾油35份、海藻18份、枸杞16份、葛根12份、桑椹9份、甘草9份、生地8份、白术6份、丹参6份、当归5份、知母5份、玉米须5份、赤芍4份、天冬2.5份比例调配；
（5）混合：将调配好的原料用高速混合搅拌机充分混合均匀；
（6）灭菌：用钴-60灭菌；
（7）灌装胶囊：在洁净室内用0号胶囊灌装；
（8）成型产品：将灌装后的胶囊装瓶，贴标，喷码即得具有降血糖功效的南极磷虾油保健胶囊。
实施例
2
：
一种降血糖南极磷虾油保健胶囊，通过以下步骤制备：
（1）原料预处理：将所用中草药分拣，去除杂质、霉变和有病虫害的原料等；
（2）干燥：将原料分别在微波真空干燥机中干燥至恒重；
（3）粉碎：分别将南极磷虾油和中草药原料用超微型粉碎机粉碎，过2000目筛；
（4）称量调配：将粉碎后的原料按照南极磷虾油40份、海藻15份、枸杞18份、葛根10份、桑椹10份、甘草8份、生地10份、白术4份、丹参8份、当归4份、知母6份、玉米须4份、赤芍5份、天冬2份比例调配；
（5）混合：将调配好的原料用高速混合搅拌机充分混合均匀；
（6）灭菌：用钴-60灭菌；
（7）灌装胶囊：在洁净室内用0号胶囊灌装；
（8）成型产品：将灌装后的胶囊装瓶，贴标，喷码即得具有降血糖功效的南极磷虾油保健胶囊。
实施例
3
：
一种降血糖南极磷虾油保健胶囊，通过以下步骤制备：
（1）原料预处理：将所用中草药分拣，去除杂质、霉变和有病虫害的原料等；
（2）干燥：将原料分别在微波真空干燥机中干燥至恒重；
（3）粉碎：分别将南极磷虾油和中草药原料用超微型粉碎机粉碎，过2000目筛；
（4）称量调配：将粉碎后的原料按照南极磷虾油30份、海藻20份、枸杞15份、葛根14份、桑椹8份、甘草10份、生地6份、白术8份、丹参5份、当归6份、知母4份、玉米须6份、赤芍3份、天冬3份比例调配；
（5）混合：将调配好的原料用高速混合搅拌机充分混合均匀；
（6）灭菌：用钴-60灭菌；
（7）灌装胶囊：在洁净室内用0号胶囊灌装；
（8）成型产品：将灌装后的胶囊装瓶，贴标，喷码即得具有降血糖功效的南极磷虾油保健胶囊。
以上实施例仅用于说明本发明的技术方案，而非对其进行限制；尽管参照前述实施例对被发明进行了详细的说明，但对于本领域的普通技术人员来说，依然可以对前述实施例所记载的技术方案进行修改，或者对其中部分技术特征进行等同替换；而对这些修改或者替换，并不使相应技术方案的本质脱离本发明所要求保护的技术方案的精神和范围。
Claims (1)
1.一种降血糖南极磷虾油保健胶囊，其特征在于通过以下步骤制备：
（1）原料预处理：将所用中草药分拣，去除杂质、霉变和有病虫害的原料等；
（2）干燥：将原料分别在微波真空干燥机中干燥至恒重；
（3）粉碎：分别将南极磷虾油和中草药原料用超微型粉碎机粉碎，过2000目筛；
（4）称量调配：将粉碎后的原料按照南极磷虾油30～40份、海藻15～20份、枸杞15～18份、葛根10～14份、桑椹8～10份、甘草8～10份、生地6～10份、白术4～8份、丹参5～8份、当归4～6份、知母4～6份、玉米须4～6份、赤芍3～5份、天冬2～3份比例调配；
（5）混合：将调配好的原料用高速混合搅拌机充分混合均匀；
（6）灭菌：用钴-60灭菌；
（7）灌装胶囊：在洁净室内用0号胶囊灌装；
（8）成型产品：将灌装后的胶囊装瓶，贴标，喷码即得具有降血糖功效的南极磷虾油保健胶囊。
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Application publication date: 20160831 |